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Wainberg MA

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Publications:

Title Authors Year Journal
Cotransfection of mutated forms of human immunodeficiency virus type 1 Gag-Pol with wild-type constructs can interfere with processing and viral replication. Wainberg MA Journal of human virology
Antiviral activity and resistance profile of phosphazid--a novel prodrug of AZT. Wainberg MA Nucleosides & nucleotides
Interactions between human immunodeficiency virus type 1 reverse transcriptase, tRNA primer, and nucleocapsid protein during reverse transcription. Wainberg MA Journal of human virology
The role of Tat in HIV-1 replication: an activator and/or a suppressor? Wainberg MA AIDS reviews
[Antiviral strategies in the replication of human immunodeficiency virus]. Wainberg MA L'unión médicale du Canada
Role of genetic diversity amongst HIV-1 non-B subtypes in drug resistance: a systematic review of virologic and biochemical evidence. Wainberg MA AIDS reviews
The Effect of Mutations at Position E138 in HIV-1 Reverse Transcriptase and their Interactions with the M184I Mutation in Defining Patterns of Resistance to the Non-Nucleoside Reverse Transcriptase Inhibitors Rilpivirine and Etravirine. Wainberg MA 2013 Antimicrobial agents and chemotherapy
Basis for the Early and Preferential Selection of the E138K Substitution in HIV-1 Reverse Transcriptase with Etravirine. Wainberg MA 2013 Antimicrobial agents and chemotherapy
The preferential selection of K65R in HIV-1 subtype C is attenuated by nucleotide polymorphisms at thymidine analogue mutation sites. Wainberg MA 2013 The Journal of antimicrobial chemotherapy
Evolution of HIV integrase resistance mutations. Wainberg MA 2013 Current opinion in infectious diseases
Biochemical Mechanism of HIV-1 Resistance to Rilpivirine. Wainberg MA 2012 The Journal of biological chemistry
Maraviroc and other HIV-1 entry inhibitors exhibit a class-specific redistribution effect that results in increased extracellular viral load. Wainberg MA 2012 Antimicrobial agents and chemotherapy
Transmission dynamics of the M184V drug resistance mutation in primary HIV infection. Wainberg MA 2011 The Journal of antimicrobial chemotherapy
Characterization of the E138K resistance mutation in HIV-1 reverse transcriptase conferring susceptibility to etravirine in B and non-B HIV-1 subtypes. Wainberg MA 2011 Antimicrobial agents and chemotherapy
Subtype diversity associated with the development of HIV-1 resistance to integrase inhibitors. Wainberg MA 2011 Journal of medical virology
A template-dependent dislocation mechanism potentiates K65R reverse transcriptase mutation development in subtype C variants of HIV-1. Wainberg MA 2011 PloS one
Compensation by the E138K mutation in HIV-1 reverse transcriptase for deficits in viral replication capacity and enzyme processivity associated with the M184I/V mutations. Wainberg MA 2011 Journal of virology
Higher levels of Zidovudine resistant HIV in the colon compared to blood and other gastrointestinal compartments in HIV infection. Wainberg MA 2010 Retrovirology
Differential impact of the HIV-1 non-nucleoside reverse transcriptase inhibitor mutations K103N and M230L on viral replication and enzyme function. Wainberg MA 2010 The Journal of antimicrobial chemotherapy
Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV-1 subtype B and subtype C. Wainberg MA 2010 Retrovirology
Stage-dependent inhibition of HIV-1 replication by antiretroviral drugs in cell culture. Wainberg MA 2010 Antimicrobial agents and chemotherapy
Factors affecting template usage in the development of K65R resistance in subtype C variants of HIV type-1. Wainberg MA 2010 Antiviral chemistry & chemotherapy
Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance. Wainberg MA 2009 Retrovirology
Template usage is responsible for the preferential acquisition of the K65R reverse transcriptase mutation in subtype C variants of human immunodeficiency virus type 1. Wainberg MA 2009 Journal of virology
Apricitabine does not select additional drug resistance mutations in tissue culture in human immunodeficiency virus type 1 variants containing K65R, M184V, or M184V plus thymidine analogue mutations. Wainberg MA 2009 Antimicrobial agents and chemotherapy
Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C. Wainberg MA 2009 The Journal of infectious diseases
Prevalence of the K65R resistance reverse transcriptase mutation in different HIV-1 subtypes in Israel. Wainberg MA 2009 Journal of medical virology
Human immunodeficiency virus type 1 recombinant reverse transcriptase enzymes containing the G190A and Y181C resistance mutations remain sensitive to etravirine. Wainberg MA 2009 Antimicrobial agents and chemotherapy
HIV inactivation by cross-linking of photo-labeled anti-retroviral compounds with HIV reverse transcriptase. Wainberg MA 2009 Vaccine
Multidrug-resistant variants of HIV type 1 (HIV-1) can exist in cells as defective quasispecies and be rescued by superinfection with other defective HIV-1 variants. Wainberg MA 2009 The Journal of infectious diseases
Near full-length genomic analysis of a novel subtype A1/C recombinant HIV type 1 isolate from Canada. Wainberg MA 2008 AIDS research and human retroviruses
Transmission networks of drug resistance acquired in primary/early stage HIV infection. Wainberg MA 2008 AIDS (London, England)
Kinetics of inhibition of HIV type 1 reverse transcriptase-bearing NRTI-associated mutations by apricitabine triphosphate. Wainberg MA 2007 Antiviral chemistry & chemotherapy
Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine. Wainberg MA 2007 Antimicrobial agents and chemotherapy
Diminished efficiency of HIV-1 reverse transcriptase containing the K65R and M184V drug resistance mutations. Wainberg MA 2007 AIDS (London, England)
High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. Wainberg MA 2006 Antimicrobial agents and chemotherapy
HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture. Wainberg MA 2006 AIDS (London, England)
Effects of drug resistance on viral load in patients failing antiretroviral therapy. Wainberg MA 2006 Journal of medical virology
Changing patterns in the selection of viral mutations among patients receiving nucleoside and nucleotide drug combinations directed against human immunodeficiency virus type 1 reverse transcriptase. Wainberg MA 2005 Antimicrobial agents and chemotherapy
Accuracy, precision, and consistency of expert HIV type 1 genotype interpretation: an international comparison (The GUESS Study). Wainberg MA 2005 Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Challenges for the clinical development of new nucleoside reverse transcriptase inhibitors for HIV infection. Wainberg MA 2005 Antiviral therapy
Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs. Wainberg MA 2005 Journal of the International AIDS Society
Substitutions in the reverse transcriptase and protease genes of HIV-1 subtype B in untreated individuals and patients treated with antiretroviral drugs. Wainberg MA 2005 MedGenMed : Medscape general medicine
A HIV-1 minimal gag protein is superior to nucleocapsid at in vitro annealing and exhibits multimerization-induced inhibition of reverse transcription. Wainberg MA 2005 The Journal of biological chemistry
Impaired rescue of chain-terminated DNA synthesis associated with the L74V mutation in human immunodeficiency virus type 1 reverse transcriptase. Wainberg MA 2005 Antimicrob Agents Chemother
Persistence of multidrug-resistant HIV-1 in primary infection leading to superinfection. Wainberg MA 2004 AIDS (London, England)
Variability in the PR and RT genes of HIV-1 isolated from recently infected subjects. Wainberg MA 2004 Antiviral chemistry & chemotherapy
Diminished representation of HIV-1 variants containing select drug resistance-conferring mutations in primary HIV-1 infection. Wainberg MA 2004 Journal of acquired immune deficiency syndromes
Rationale for maintenance of the M184v resistance mutation in human immunodeficiency virus type 1 reverse transcriptase in treatment experienced patients. Wainberg MA 2004 The new microbiologica
The impact of the M184V substitution on drug resistance and viral fitness. Wainberg MA 2004 Expert review of anti-infective therapy
Mutations and polymorphisms associated with antiretroviral drugs in HIV-1C-infected African patients. Wainberg MA 2004 Antiviral chemistry & chemotherapy
Differential maintenance of the M184V substitution in the reverse transcriptase of human immunodeficiency virus type 1 by various nucleoside antiretroviral agents in tissue culture. Wainberg MA 2004 Antimicrobial agents and chemotherapy
Nucleotide and amino acid polymorphisms at drug resistance sites in non-B-subtype variants of human immunodeficiency virus type 1. Wainberg MA 2004 Antimicrobial agents and chemotherapy
Relationships among various nucleoside resistance-conferring mutations in the reverse transcriptase of HIV-1. Wainberg MA 2004 The Journal of antimicrobial chemotherapy
Resistance issues with new nucleoside/nucleotide backbone options. Wainberg MA 2004 Journal of acquired immune deficiency syndromes
Nucleoside and nucleotide analogue reverse transcriptase inhibitors: a clinical review of antiretroviral resistance. Wainberg MA 2003 Antivir Ther
Lamivudine can exert a modest antiviral effect against human immunodeficiency virus type 1 containing the M184V mutation. Wainberg MA 2003 Antimicrobial agents and chemotherapy
Didanosine, interferon-alfa and ribavirin: a highly synergistic combination with potential activity against HIV-1 and hepatitis C virus. Wainberg MA 2003 AIDS (London, England)
Drug resistance profiles of recombinant reverse transcriptases from human immunodeficiency virus type 1 subtypes A/E, B, and C. Wainberg MA 2003 AIDS research and human retroviruses
Multiple effects of the M184V resistance mutation in the reverse transcriptase of human immunodeficiency virus type 1. Wainberg MA 2003 Clinical and diagnostic laboratory immunology
Negative effect of the M184V mutation in HIV-1 reverse transcriptase on initiation of viral DNA synthesis. Wainberg MA 2003 Virology
A V106M mutation in HIV-1 clade C viruses exposed to efavirenz confers cross-resistance to non-nucleoside reverse transcriptase inhibitors. Wainberg MA 2003 AIDS (London, England)
Molecular impact of the M184V mutation in human immunodeficiency virus type 1 reverse transcriptase. Wainberg MA 2003 Antimicrobial agents and chemotherapy
Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity. Wainberg MA 2003 Journal of virology
The M184V substitution in human immunodeficiency virus type 1 reverse transcriptase delays the development of resistance to amprenavir and efavirenz in subtype B and C clinical isolates. Wainberg MA 2003 Antimicrobial agents and chemotherapy
The Tat protein of human immunodeficiency virus type 1 (HIV-1) can promote placement of tRNA primer onto viral RNA and suppress later DNA polymerization in HIV-1 reverse transcription. Wainberg MA 2002 Journal of virology
The M184V mutation in HIV-1 reverse transcriptase reduces the restoration of wild-type replication by attenuated viruses. Wainberg MA 2002 AIDS (London, England)
Nonradioactive detection of retroviral-associated RNase H activity in a microplate-based, high-throughput format. Wainberg MA 2002 BioTechniques
Pressure of zidovudine accelerates the reversion of lamivudine resistance-conferring M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1. Wainberg MA 2002 Antimicrobial agents and chemotherapy
HIV-1 drug resistance: can we overcome? Wainberg MA 2002 Expert opinion on biological therapy
Polymorphisms of cytotoxic T-lymphocyte (CTL) and T-helper epitopes within reverse transcriptase (RT) of HIV-1 subtype C from Ethiopia and Botswana following selection of antiretroviral drug resistance. Wainberg MA 2002 Antiviral research
Co-receptor usage and HIV-1 intra-clade C polymorphisms in the protease and reverse transcriptase genes of HIV-1 isolates from Ethiopia and Botswana. Wainberg MA 2002 Antiviral therapy
The M184V mutation in reverse transcriptase can delay reversion of attenuated variants of simian immunodeficiency virus. Wainberg MA 2002 Journal of virology
Genetic divergence of human immunodeficiency virus type 1 Ethiopian clade C reverse transcriptase (RT) and rapid development of resistance against nonnucleoside inhibitors of RT. Wainberg MA 2002 Antimicrobial agents and chemotherapy
Virulence and reduced fitness of simian immunodeficiency virus with the M184V mutation in reverse transcriptase. Wainberg MA 2002 Journal of virology
Structural and functional properties of the HIV-1 RNA-tRNA(Lys)3 primer complex annealed by the nucleocapsid protein: comparison with the heat-annealed complex. Wainberg MA 2002 RNA (New York, N.Y.)
Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection. Wainberg MA 2002 Journal of virology
Resistance profiles to antiretroviral drugs in HIV-1 drug-naive patients in Argentina. Wainberg MA 2001 Antiviral therapy
HIV-1 nucleocapsid protein and the secondary structure of the binary complex formed between tRNA(Lys.3) and viral RNA template play different roles during initiation of (-) strand DNA reverse transcription. Wainberg MA 2001 The Journal of biological chemistry
Role for human immunodeficiency virus type 1 Tat protein in suppression of viral reverse transcriptase activity during late stages of viral replication. Wainberg MA 2001 Journal of virology
Analysis of efficiency and fidelity of HIV-1 (+)-strand DNA synthesis reveals a novel rate-limiting step during retroviral reverse transcription. Wainberg MA 2001 The Journal of biological chemistry
Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use. Investigators of the Quebec Primary Infection Study. Wainberg MA 2000 AIDS (London, England)
Selection and characterization of human immunodeficiency virus type 1 variants resistant to the (+) and (-) enantiomers of 2'-deoxy-3'-oxa-4'-thio-5-fluorocytidine. Wainberg MA 2000 Antimicrobial agents and chemotherapy
The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis. Wainberg MA 2000 J Virol
Biochemical mechanisms involved in overcoming HIV resistance to nucleoside inhibitors of reverse transcriptase. Wainberg MA 2000 Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Human immunodeficiency virus type-1 reverse transcription can be inhibited in vitro by oligonucleotides that target both natural and synthetic tRNA primers. Wainberg MA 2000 Nucleic acids research
The effect of mutations in the HIV-1 nucleocapsid protein on strand transfer in cell-free reverse transcription reactions. Wainberg MA 2000 Nucleic acids research
Sequences within Pr160gag-pol affecting the selective packaging of primer tRNA(Lys3) into HIV-1. Wainberg MA 2000 Journal of molecular biology
Resistance to antiretroviral drugs in patients with primary HIV-1 infection. Investigators of the Quebec Primary Infection Study. Wainberg MA 2000 International journal of antimicrobial agents
Selection of resistance-conferring mutations in HIV-1 by the nucleoside reverse transcriptase inhibitors (+/-)dOTC and (+/-)dOTFC. Wainberg MA 2000 Antiviral chemistry & chemotherapy
Stavudine resistance: an update on susceptibility following prolonged therapy. Wainberg MA 1999 Antiviral therapy
Selection and characterization of HIV-1 variants resistant to the (+) and (-) enantiomers of 2'-deoxy-3'-oxa-4'-thiocytidine (dOTC). Wainberg MA 1999 Antiviral therapy
HIV-1 reverse transcription: a brief overview focused on structure-function relationships among molecules involved in initiation of the reaction. Wainberg MA 1999 Archives of biochemistry and biophysics
Temporal coordination between initiation of HIV (+)-strand DNA synthesis and primer removal. Wainberg MA 1999 The Journal of biological chemistry
In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA. Wainberg MA 1999 Antivir Ther
Sensitivity and resistance to (+)-calanolide A of wild-type and mutated forms of HIV-1 reverse transcriptase. Wainberg MA 1999 Antiviral therapy
Mechanism of action and in vitro activity of 1',3'-dioxolanylpurine nucleoside analogues against sensitive and drug-resistant human immunodeficiency virus type 1 variants. Wainberg MA 1999 Antimicrobial agents and chemotherapy
Anti-human immunodeficiency virus type 1 activity, intracellular metabolism, and pharmacokinetic evaluation of 2'-deoxy-3'-oxa-4'-thiocytidine. Wainberg MA 1999 Antimicrobial agents and chemotherapy
Reverse transcriptase inhibitors can selectively block the synthesis of differently sized viral DNA transcripts in cells acutely infected with human immunodeficiency virus type 1. Wainberg MA 1999 Journal of virology
Resistance mutations selected in vivo under therapy with anti-HIV drug HBY 097 differ from resistance pattern selected in vitro. Wainberg MA 1999 Antiviral research
The role of Pr55(gag) in the annealing of tRNA3Lys to human immunodeficiency virus type 1 genomic RNA. Wainberg MA 1999 Journal of virology
The thiocarboxanilide nonnucleoside inhibitor UC781 restores antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus type 1. Wainberg MA 1999 Antimicrobial agents and chemotherapy
Dominance of the E89G substitution in HIV-1 reverse transcriptase in regard to increased polymerase processivity and patterns of pausing. Wainberg MA 1998 The Journal of biological chemistry
Inducible expression of IkappaBalpha repressor mutants interferes with NF-kappaB activity and HIV-1 replication in Jurkat T cells. Wainberg MA 1998 The Journal of biological chemistry
Enhanced impairment of chain elongation by inhibitors of HIV reverse transcriptase in cell-free reactions yielding longer DNA products. Wainberg MA 1998 Nucleic acids research
HIV-specific cytotoxic T-lymphocyte activity in immunologically normal HIV-infected persons. Wainberg MA 1998 AIDS (London, England)
Characterization of human immunodeficiency virus type-1 (HIV-1) particles that express protease-reverse transcriptase fusion proteins. Wainberg MA 1998 Journal of molecular biology
Virtues of being faithful: can we limit the genetic variation in human immunodeficiency virus? Wainberg MA 1998 Journal of molecular medicine (Berlin, Germany)
Effect of HIV constructs containing protease-reverse transcriptase fusion proteins on viral replication. Wainberg MA 1998 AIDS (London, England)
Mechanistic studies of early pausing events during initiation of HIV-1 reverse transcription. Wainberg MA 1998 The Journal of biological chemistry
Efficient gap repair catalyzed in vitro by an intrinsic DNA polymerase activity of human immunodeficiency virus type 1 integrase. Wainberg MA 1998 J Virol
Neutralizing antibodies directed against the V3 loop select for different escape variants in a virus with mutated reverse transcriptase (M184V) than in wild-type human immunodeficiency virus type 1. Wainberg MA 1998 AIDS research and human retroviruses
Endogenous reverse transcriptase assays reveal synergy between combinations of the M184V and other drug resistance-conferring mutations in interactions with nucleoside analog triphosphates. Wainberg MA 1998 Journal of molecular biology
Diminished HIV-1 sensitivity to stavudine in patients on prolonged therapy occurs only at low levels and cannot be attributed to any single amino acid substitution in reverse transcriptase. Wainberg MA 1998 Antiviral therapy
The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity. Wainberg MA 1997 Journal of virology
Increased fidelity of drug-selected M184V mutated HIV-1 reverse transcriptase as the basis for the effectiveness of 3TC in HIV clinical trials. Wainberg MA 1997 Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K
Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase. Wainberg MA 1997 J Virol
Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1. Wainberg MA 1997 Nucleic acids research
Mutations at codon 184 in simian immunodeficiency virus reverse transcriptase confer resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine. Wainberg MA 1997 Antimicrobial agents and chemotherapy
The roles of the human immunodeficiency virus type 1 Pol protein and the primer binding site in the placement of primer tRNA(3Lys) onto viral genomic RNA. Wainberg MA 1997 Journal of virology
Combination of a drug targeting the cell with a drug targeting the virus controls human immunodeficiency virus type 1 resistance. Wainberg MA 1997 AIDS research and human retroviruses
Effects of mutations in Pr160gag-pol upon tRNA(Lys3) and Pr160gag-plo incorporation into HIV-1. Wainberg MA 1997 Journal of molecular biology
The K65R mutation confers increased DNA polymerase processivity to HIV-1 reverse transcriptase. Wainberg MA 1996 The Journal of biological chemistry
Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2'-dideoxy-3'-thiacytidine by mutated M184V human immunodeficiency virus type 1. Wainberg MA 1996 J Virol
Effects of modifying the tRNA(3Lys) anticodon on the initiation of human immunodeficiency virus type 1 reverse transcription. Wainberg MA 1996 Journal of virology
Effectiveness of 3TC in HIV clinical trials may be due in part to the M184V substitution in 3TC-resistant HIV-1 reverse transcriptase. Wainberg MA 1996 AIDS (London, England)
Multiple forms of tRNA(Lys3) in HIV-1. Wainberg MA 1996 Biochemical and biophysical research communications
HIV-1 reverse transcriptase shows no specificity for the binding of primer tRNA(Lys3). Wainberg MA 1996 Biochemical and biophysical research communications
Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minus-strand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site. Wainberg MA 1996 Journal of virology
The nucleoside analog-resistant E89G mutant of human immunodeficiency virus type 1 reverse transcriptase displays a broader cross-resistance that extends to nonnucleoside inhibitors. Wainberg MA 1996 Antimicrobial agents and chemotherapy
Resistance to (-)-2',3'-dideoxy-3'-thiacytidine (3TC) in HIV-1 isolated from paediatric patients. Wainberg MA 1996 Antiviral therapy
Studies of neutralizing monoclonal antibody to human immunodeficiency virus type 1 reverse transcriptase: antagonistic and synergistic effects in reactions performed in the presence of nucleoside and nonnucleoside inhibitors, respectively. Wainberg MA 1996 Journal of virology
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase. Wainberg MA 1996 Science (New York, N.Y.)
Single-step purification of recombinant wild-type and mutant HIV-1 reverse transcriptase. Wainberg MA 1996 Protein expression and purification
Effects of 3'-deoxynucleoside 5'-triphosphate concentrations on chain termination by nucleoside analogs during human immunodeficiency virus type 1 reverse transcription of minus-strand strong-stop DNA. Wainberg MA 1996 Journal of virology
Human immunodeficiency virus type 1 reverse transcriptase and early events in reverse transcription. Wainberg MA 1996 Advances in virus research
In vitro selection and molecular characterization of human immunodeficiency virus type 1 with reduced sensitivity to 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). Wainberg MA 1996 Antiviral research
Effects of non-nucleoside inhibitors of human immunodeficiency virus type 1 in cell-free recombinant reverse transcriptase assays. Wainberg MA 1995 The Journal of biological chemistry
K65R mutation of human immunodeficiency virus type 1 reverse transcriptase encodes cross-resistance to 9-(2-phosphonylmethoxyethyl)adenine. Wainberg MA 1995 Antimicrobial agents and chemotherapy
Targeting HIV reverse transcriptase in novel ways. Wainberg MA 1995 Nature medicine
Insulin-like growth factor 1 and insulin inhibit HIV type 1 replication in cultured cells. Wainberg MA 1995 AIDS research and human retroviruses
Development of HIV-1 resistance to (-)2'-deoxy-3'-thiacytidine in patients with AIDS or advanced AIDS-related complex. Wainberg MA 1995 AIDS (London, England)
Analysis of Primer Extension and the First Template Switch during Human Immunodeficiency Virus Reverse Transcription. Wainberg MA 1995 Journal of biomedical science
Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs. Wainberg MA 1995 Proceedings of the National Academy of Sciences of the United States of America
Antiviral activity and protection of cells against human immunodeficiency virus type-1 using an antisense oligodeoxyribonucleotide phosphorothioate complementary to the 5'-LTR region of the viral genome. Wainberg MA 1995 Gene
Sequence-specific inhibition of gene expression by a novel antisense oligodeoxynucleotide phosphorothioate directed against a nonregulatory region of the human immunodeficiency virus type 1 genome. Wainberg MA 1995 Journal of virology
[Molecular basis and clinical significance of HIV-1 resistance to nucleoside compounds]. Wainberg MA 1995 Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie
Inhibition of human immunodeficiency virus type 1 multiplication by transforming growth factor beta 1 and AZT in HIV-1-infected myeloid cells. Wainberg MA 1995 Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Synergistic inhibition of HIV-1 reverse transcriptase DNA polymerase activity and virus replication in vitro by combinations of carboxanilide nonnucleoside compounds. Wainberg MA 1995 Biochemistry
Comparison of cord blood and peripheral blood mononuclear cells as targets for viral isolation and drug sensitivity studies involving human immunodeficiency virus type 1. Wainberg MA 1994 Journal of clinical microbiology
DNA found in human immunodeficiency virus type 1 particles may not be required for infectivity. Wainberg MA 1994 The Journal of general virology
Development and significance of nucleoside drug resistance in infection caused by the human immunodeficiency virus type 1. Wainberg MA 1994 Clinical and investigative medicine. Médecine clinique et experimentale
Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction. Wainberg MA 1994 The Journal of biological chemistry
Effect of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine on establishment of human immunodeficiency virus type 1 infection in cultured CD8+ lymphocytes. Wainberg MA 1994 Antimicrobial agents and chemotherapy
Mature reverse transcriptase (p66/p51) is responsible for low levels of viral DNA found in human immunodeficiency virus type 1 (HIV-1). Wainberg MA 1994 Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K
Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine. Wainberg MA 1994 Antimicrobial agents and chemotherapy
Identification of novel mutations that confer drug resistance in the human immunodeficiency virus polymerase gene. Wainberg MA 1994 Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K
Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particles. Wainberg MA 1994 Journal of virology
The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2', 3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro. Wainberg MA 1994 The Journal of biological chemistry
Clinical correlates and molecular basis of HIV drug resistance. Wainberg MA 1993 Journal of acquired immune deficiency syndromes
High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase. Wainberg MA 1993 Antimicrobial agents and chemotherapy
Infection of human monocyte-derived macrophages by human immunodeficiency virus mediated by cell-to-cell transmission. Wainberg MA 1993 Journal of medical virology
Generation and characterization of murine monoclonal antibodies reactive against N-terminal and other regions of HIV-1 reverse transcriptase. Wainberg MA 1993 Journal of medical virology
HIV resistance to anti-viral drugs. Wainberg MA 1993 Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.]
The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine. Wainberg MA 1993 Antimicrob Agents Chemother
Variable tRNA content in HIV-1IIIB. Wainberg MA 1992 Biochemical and biophysical research communications
Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine. Wainberg MA 1992 J Virol
In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine. Wainberg MA 1992 Journal of virology
Differential susceptibilities of U-937 cell clones to infection by human immunodeficiency virus type 1. Wainberg MA 1992 Journal of virology
Strategies in the treatment of AIDS and related diseases: the lessons of cancer chemotherapy. Wainberg MA 1992 Cancer investigation
Clinical significance and characterization of AZT-resistant strains of HIV-1. Wainberg MA 1991 The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses
Recovery of infectious human immunodeficiency virus type 1 after fusion of defectively infected clones of U-937 cells. Wainberg MA 1991 Journal of virology
High frequency of isolation of defective human immunodeficiency virus type 1 and heterogeneity of viral gene expression in clones of infected U-937 cells. Wainberg MA 1990 Journal of virology
Characterization of reverse transcriptase activity and susceptibility to other nucleosides of AZT-resistant variants of HIV-1. Results from the Canadian AZT Multicentre Study. Wainberg MA 1990 Annals of the New York Academy of Sciences
Resistance to infection by HIV-1 of peripheral blood mononuclear cells from HIV-1-infected patients is probably mediated by neutralizing antibodies. Wainberg MA 1990 Journal of immunology (Baltimore, Md. : 1950)
AZT (zidovudine) may act postintegrationally to inhibit generation of HIV-1 progeny virus in chronically infected cells. Wainberg MA 1990 Virology
Inhibition by AZT of HIV-1 replication in acutely infected U-937 cells. Wainberg MA 1990 Journal of leukocyte biology
Inactivation of human immunodeficiency virus type 1 in tissue culture fluid and in genital secretions by the spermicide benzalkonium chloride. Wainberg MA 1990 Journal of clinical microbiology
Infection of human thymic lymphocytes by HIV-1. Wainberg MA 1990 Journal of acquired immune deficiency syndromes
Active replication of human immunodeficiency virus type 1 by peripheral blood mononuclear cells following coincubation with herpes viruses. Wainberg MA 1989 Journal of medical virology
Infection of cultured human thymic epithelial cells by human immunodeficiency virus. Wainberg MA 1989 Clinical immunology and immunopathology
Susceptibility of EBV-carrying B cell lines to infection by HIV-1: variability of production of progeny virus and expression of viral antigens. Wainberg MA 1989 Cancer letters
Infection of human monocytes/macrophages by HIV-1: effect on secretion of IL-1 activity. Wainberg MA 1988 Immunology
Heterogeneity of HIV-1 replication and antigen expression in EBV-transformed B cell lines. Wainberg MA 1988 Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K
Decreased production of transforming virus and altered antigenic behaviour in cultured avian sarcoma cells. Wainberg MA 1979 The Journal of general virology
Effect of glucosamine on virus production and antigen expression in avian sarcoma virus-transformed cells. Wainberg MA 1978 Canadian journal of microbiology
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