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Washington MT

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Publications:

Title Authors Year Journal
PCNA trimer instability inhibits translesion synthesis by DNA polymerase η and by DNA polymerase δ. Washington MT 2013 DNA repair
Structure and functional analysis of the BRCT domain of translesion synthesis DNA polymerase Rev1. Washington MT 2013 Biochemistry
Crystal structure of SUMO-modified proliferating cell nuclear antigen. Washington MT 2011 Journal of molecular biology
Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Washington MT 2010 Nature structural & molecular biology
Pre-steady state kinetic studies of the fidelity of nucleotide incorporation by yeast DNA polymerase delta. Washington MT 2010 Biochemistry
Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis. Washington MT 2008 Biochemistry
Substitution of a residue contacting the triphosphate moiety of the incoming nucleotide increases the fidelity of yeast DNA polymerase zeta. Washington MT 2008 Nucleic acids research
Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini. Washington MT 2006 Proceedings of the National Academy of Sciences of the United States of America
Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa. Washington MT 2005 Molecular and cellular biology
Mechanism of efficient and accurate nucleotide incorporation opposite 7,8-dihydro-8-oxoguanine by Saccharomyces cerevisiae DNA polymerase eta. Washington MT 2005 Molecular and cellular biology
Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa. Washington MT 2004 Molecular and cellular biology
Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta. Washington MT 2004 Molecular and cellular biology
Human DNA polymerase iota utilizes different nucleotide incorporation mechanisms dependent upon the template base. Washington MT 2004 Molecular and cellular biology
Yeast DNA polymerase eta makes functional contacts with the DNA minor groove only at the incoming nucleoside triphosphate. Washington MT 2003 Proceedings of the National Academy of Sciences of the United States of America
Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase eta. Washington MT 2003 Proceedings of the National Academy of Sciences of the United States of America
Requirement of Watson-Crick hydrogen bonding for DNA synthesis by yeast DNA polymerase eta. Washington MT 2003 Molecular and cellular biology
The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme. Washington MT 2003 Molecular and cellular biology
Human DNA polymerase kappa uses template-primer misalignment as a novel means for extending mispaired termini and for generating single-base deletions. Washington MT 2003 Genes Dev
Translesion synthesis past acrolein-derived DNA adduct, gamma -hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta. Washington MT 2003 The Journal of biological chemistry
Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini. Washington MT 2002 Proceedings of the National Academy of Sciences of the United States of America
Accuracy of lesion bypass by yeast and human DNA polymerase eta. Washington MT 2001 Proceedings of the National Academy of Sciences of the United States of America
Yeast DNA polymerase eta utilizes an induced-fit mechanism of nucleotide incorporation. Washington MT 2001 Cell
Inefficient bypass of an abasic site by DNA polymerase eta. Washington MT 2001 The Journal of biological chemistry
Acidic residues critical for the activity and biological function of yeast DNA polymerase eta. Washington MT 2001 Molecular and cellular biology
Mismatch extension ability of yeast and human DNA polymerase eta. Washington MT 2001 The Journal of biological chemistry
Fidelity and damage bypass ability of Schizosaccharomyces pombe Eso1 protein, comprised of DNA polymerase eta and sister chromatid cohesion protein Ctf7. Washington MT 2001 The Journal of biological chemistry
Translesion DNA synthesis by yeast DNA polymerase eta on templates containing N2-guanine adducts of 1,3-butadiene metabolites. Washington MT 2001 The Journal of biological chemistry
Role of yeast and human DNA polymerase eta in error-free replication of damaged DNA. Washington MT 2000 Cold Spring Harbor symposia on quantitative biology
Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions. Washington MT 2000 Nature
Fidelity of human DNA polymerase eta. Washington MT 2000 The Journal of biological chemistry
Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase eta. Washington MT 2000 Proceedings of the National Academy of Sciences of the United States of America
Bridging the gap: a family of novel DNA polymerases that replicate faulty DNA. Washington MT 1999 Proceedings of the National Academy of Sciences of the United States of America
Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase eta. Washington MT 1999 The Journal of biological chemistry

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