Brown NC

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Title	Authors	Year	Journal
7-Alkyl-N(2)-substituted-3-deazaguanines. Synthesis, DNA polymerase III inhibition and antibacterial activity.	Brown NC	2011	Bioorganic & medicinal chemistry letters
Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors.	Brown NC	2006	J Med Chem
Synthesis of substituted 6-anilinouracils and their inhibition of DNA polymerase IIIC and Gram-positive bacterial growth.	Brown NC	2003	J Med Chem
DNA polymerase III of Enterococcus faecalis: expression and characterization of recombinant enzymes encoded by the polC and dnaE genes.	Brown NC	2003	Protein Expr Purif
In vitro antimicrobial activities of novel anilinouracils which selectively inhibit DNA polymerase III of gram-positive bacteria.	Brown NC	2000	Antimicrob Agents Chemother
6-Anilinouracil-based inhibitors of Bacillus subtilis DNA polymerase III: antipolymerase and antimicrobial structure-activity relationships based on substitution at uracil N3.	Brown NC	1999	J Med Chem
Inhibitors of DNA polymerase III as novel antimicrobial agents against gram-positive eubacteria.	Brown NC	1999	Antimicrob Agents Chemother
DNA polymerase III of Gram-positive eubacteria is a zinc metalloprotein conserving an essential finger-like domain.	Brown NC	1998	Biochemistry
The 3'-5' exonuclease site of DNA polymerase III from gram-positive bacteria: definition of a novel motif structure.	Brown NC	1995	Gene
Purification of DNA polymerase III of gram-positive bacteria.	Brown NC	1995	Methods in enzymology
DNA polymerase III of Mycoplasma pulmonis: isolation and characterization of the enzyme and its structural gene, polC.	Brown NC	1994	Molecular microbiology
Localization of the exonuclease and polymerase domains of Bacillus subtilis DNA polymerase III.	Brown NC	1992	Gene
Overproduction and purification of Bacillus subtilis DNA polymerase III.	Brown NC	1992	Protein Expr Purif
The molecular mechanism of inhibition of alpha-type DNA polymerases by N2-(butylphenyl)dGTP and 2-(butylanilino)dATP: variation in susceptibility to polymerization.	Brown NC	1991	Nucleic acids research
Bacillus subtilis DNA polymerase III: complete sequence, overexpression, and characterization of the polC gene.	Brown NC	1991	Gene
Development of novel inhibitor probes of DNA polymerase III based on dGTP analogs of the HPUra type: base, nucleoside and nucleotide derivatives of N2-(3,4-dichlorobenzyl)guanine.	Brown NC	1990	Nucleic acids research
Carbonyldiphosphonate, a selective inhibitor of mammalian DNA polymerase delta.	Brown NC	1989	Biochemistry
The cloned polC gene of Bacillus subtilis: characterization of the azp12 mutation and controlled in vitro synthesis of active DNA polymerase III.	Brown NC	1989	Gene
Calcium-dependent calmodulin-binding proteins associated with mammalian DNA polymerase alpha.	Brown NC	1988	Biochimica et biophysica acta
Mammalian DNA polymerase alpha: a replication-competent holoenzyme form from calf thymus.	Brown NC	1987	Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Inhibitors of Bacillus subtilis DNA polymerase III. Influence of modifications in the pyrimidine ring of anilino- and (benzylamino)pyrimidines.	Brown NC	1986	J Med Chem
Purification and characterization of DNA polymerase alpha of Chinese hamster ovary cells.	Brown NC	1985	Mol Cell Biochem
Elucidation of the mechanism of selective inhibition of mammalian DNA polymerase alpha by 2-butylanilinopurines: development and characterization of 2-(p-n-butylanilino)adenine and its deoxyribonucleotides.	Brown NC	1985	Nucleic acids research
Butylphenyl dGTP: a selective and potent inhibitor of mammalian DNA polymerase alpha.	Brown NC	1984	Nucleic acids research
Design and characterization of N2-arylaminopurines which selectively inhibit replicative DNA synthesis and replication-specific DNA polymerases: guanine derivatives active on mammalian DNA polymerase alpha and bacterial DNA polymerase III.	Brown NC	1982	Nucleic acids research
Butylanilinouracil: a selective inhibitor of HeLa cell DNA synthesis and HeLa cell DNA polymerase alpha.	Brown NC	1980	Nucleic acids research
Inhibitors of Bacillus subtilis DNA polymerase III. 6-Anilinouracils and 6-(alkylamino)uracils.	Brown NC	1980	J Med Chem
Antibody to B. subtilis DNA polymerase III: use in enzyme purification and examination of homology among replication-specific DNA polymerases.	Brown NC	1979	Nucleic acids research
Bacillus subtilis dnaF: a mutation of the gene specifying the structure of DNA polymerase III.	Brown NC	1978	Mol Gen Genet
Inhibitors of Bacillus subtilis DNA polymerase III. 6-(arylalkylamino)uracils and 6-anilinouracils.	Brown NC	1977	J Med Chem
Inhibitors of Bacillus subtilis DNA polymerase III. Structure-activity relationships of 6-(phenylhydrazino)uracils.	Brown NC	1977	J Med Chem
Bacillus subtilis DNA polymerase III is required for the replication of DNA of bacteriophages SPP-1 and phi 105.	Brown NC	1977	J Virol

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Brown NC

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