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Cazaux C

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Publications:

Title Authors Year Journal
DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation. Cazaux C 2013 The EMBO journal
DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis. Cazaux C 2013 The Journal of cell biology
DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions. Cazaux C 2012 Molecular and biochemical parasitology
A 'DNA replication' signature of progression and negative outcome in colorectal cancer. Cazaux C 2010 Oncogene
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Cazaux C 2010 Proceedings of the National Academy of Sciences of the United States of America
The R438W polymorphism of human DNA polymerase lambda triggers cellular sensitivity to camptothecin by compromising the homologous recombination repair pathway. Cazaux C 2010 Carcinogenesis
Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication. Cazaux C 2009 Molecular and cellular biology
Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ. Cazaux C 2009 PloS one
Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells. Cazaux C 2009 Molecular carcinogenesis
Regulation of DNA polymerase beta by the LMP1 oncoprotein of EBV through the nuclear factor-kappaB pathway. Cazaux C 2009 Cancer research
Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta. Cazaux C 2008 Oncogene
Biochemical studies with DNA polymerase beta and DNA polymerase beta-PAK of Trypanosoma cruzi suggest the involvement of these proteins in mitochondrial DNA maintenance. Cazaux C 2008 DNA repair
Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors. Cazaux C 2008 BMC Struct Biol
Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint. Cazaux C 2007 Cell Cycle
Analysis of DNA polymerase activity in vitro using non-radioactive primer extension assay in an automated DNA sequencer. Cazaux C 2007 Genet Mol Res
Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells. Cazaux C 2007 Nucleic acids research
Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase kappa in colorectal cancer. Cazaux C 2007 Oncogene
Enhanced expression and activity of DNA polymerase beta in chronic myelogenous leukemia. Cazaux C 2006 Anticancer Res
The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells. Cazaux C 2006 Nucleic acids research
Modulation of cellular response to cisplatin by a novel inhibitor of DNA polymerase beta. Cazaux C 2005 Mol Pharmacol
Acylphloroglucinol derivatives from Mahurea palustris. Cazaux C 2005 Journal of natural products
Adaptation to DNA damage and stimulation of genetic instability: the double-edged sword mammalian DNA polymerase kappa. Cazaux C 2005 Biochimie
Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. Cazaux C 2005 Cancer research
Evidence of finely tuned expression of DNA polymerase beta in vivo using transgenic mice. Cazaux C 2004 FEBS letters
DNA polymerase beta overexpression stimulates the Rad51-dependent homologous recombination in mammalian cells. Cazaux C 2004 Nucleic acids research
DNA polymerase beta can incorporate ribonucleotides during DNA synthesis of undamaged and CPD-damaged DNA. Cazaux C 2003 Journal of molecular biology
Deregulated DNA polymerase beta induces chromosome instability and tumorigenesis. Cazaux C 2002 Cancer research
Localisation of human DNA polymerase kappa to replication foci. Cazaux C 2002 J Cell Sci
A role for DNA polymerase beta in mutagenic UV lesion bypass. Cazaux C 2002 The Journal of biological chemistry
Deregulated DNA polymerase beta strengthens ionizing radiation-induced nucleotidic and chromosomal instabilities. Cazaux C 2002 Oncogene
Involvement of DNA polymerase beta in DNA replication and mutagenic consequences. Cazaux C 2002 Journal of molecular biology
Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents. Cazaux C 2001 Oncogene
DNA polymerase beta imbalance increases apoptosis and mutagenesis induced by oxidative stress. Cazaux C 2001 FEBS letters
Antitumor activity of 2',3'-dideoxycytidine nucleotide analog against tumors up-regulating DNA polymerase beta. Cazaux C 2001 Mol Pharmacol
Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells. Cazaux C 2000 The FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Mutator phenotype of BCR--ABL transfected Ba/F3 cell lines and its association with enhanced expression of DNA polymerase beta. Cazaux C 1999 Oncogene
Overexpression of DNA polymerase beta: a genomic instability enhancer process. Cazaux C 1999 FASEB J
Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs. Cazaux C 1998 Proceedings of the National Academy of Sciences of the United States of America
Overexpression of DNA polymerase beta sensitizes mammalian cells to 2',3'-deoxycytidine and 3'-azido-3'-deoxythymidine. Cazaux C 1997 Cancer research
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