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Cazaux C

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Publications:

Title Authors Year Journal
DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis. Cazaux C 2013 The Journal of cell biology
DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation. Cazaux C 2013 The EMBO journal
DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions. Cazaux C 2012 Molecular and biochemical parasitology
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Cazaux C 2010 Proceedings of the National Academy of Sciences of the United States of America
A 'DNA replication' signature of progression and negative outcome in colorectal cancer. Cazaux C 2010 Oncogene
The R438W polymorphism of human DNA polymerase lambda triggers cellular sensitivity to camptothecin by compromising the homologous recombination repair pathway. Cazaux C 2010 Carcinogenesis
Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells. Cazaux C 2009 Molecular carcinogenesis
Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ. Cazaux C 2009 PloS one
Regulation of DNA polymerase beta by the LMP1 oncoprotein of EBV through the nuclear factor-kappaB pathway. Cazaux C 2009 Cancer research
Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication. Cazaux C 2009 Molecular and cellular biology
Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors. Cazaux C 2008 BMC Struct Biol
Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta. Cazaux C 2008 Oncogene
Biochemical studies with DNA polymerase beta and DNA polymerase beta-PAK of Trypanosoma cruzi suggest the involvement of these proteins in mitochondrial DNA maintenance. Cazaux C 2008 DNA repair
Analysis of DNA polymerase activity in vitro using non-radioactive primer extension assay in an automated DNA sequencer. Cazaux C 2007 Genet Mol Res
Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells. Cazaux C 2007 Nucleic acids research
Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase kappa in colorectal cancer. Cazaux C 2007 Oncogene
Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint. Cazaux C 2007 Cell Cycle
The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells. Cazaux C 2006 Nucleic acids research
Enhanced expression and activity of DNA polymerase beta in chronic myelogenous leukemia. Cazaux C 2006 Anticancer Res
Acylphloroglucinol derivatives from Mahurea palustris. Cazaux C 2005 Journal of natural products
Adaptation to DNA damage and stimulation of genetic instability: the double-edged sword mammalian DNA polymerase kappa. Cazaux C 2005 Biochimie
Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. Cazaux C 2005 Cancer research
Modulation of cellular response to cisplatin by a novel inhibitor of DNA polymerase beta. Cazaux C 2005 Mol Pharmacol
Evidence of finely tuned expression of DNA polymerase beta in vivo using transgenic mice. Cazaux C 2004 FEBS letters
DNA polymerase beta overexpression stimulates the Rad51-dependent homologous recombination in mammalian cells. Cazaux C 2004 Nucleic acids research
DNA polymerase beta can incorporate ribonucleotides during DNA synthesis of undamaged and CPD-damaged DNA. Cazaux C 2003 Journal of molecular biology
Localisation of human DNA polymerase kappa to replication foci. Cazaux C 2002 J Cell Sci
Deregulated DNA polymerase beta strengthens ionizing radiation-induced nucleotidic and chromosomal instabilities. Cazaux C 2002 Oncogene
Deregulated DNA polymerase beta induces chromosome instability and tumorigenesis. Cazaux C 2002 Cancer research
Involvement of DNA polymerase beta in DNA replication and mutagenic consequences. Cazaux C 2002 Journal of molecular biology
A role for DNA polymerase beta in mutagenic UV lesion bypass. Cazaux C 2002 The Journal of biological chemistry
Antitumor activity of 2',3'-dideoxycytidine nucleotide analog against tumors up-regulating DNA polymerase beta. Cazaux C 2001 Mol Pharmacol
Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents. Cazaux C 2001 Oncogene
DNA polymerase beta imbalance increases apoptosis and mutagenesis induced by oxidative stress. Cazaux C 2001 FEBS letters
Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells. Cazaux C 2000 The FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Mutator phenotype of BCR--ABL transfected Ba/F3 cell lines and its association with enhanced expression of DNA polymerase beta. Cazaux C 1999 Oncogene
Overexpression of DNA polymerase beta: a genomic instability enhancer process. Cazaux C 1999 FASEB J
Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs. Cazaux C 1998 Proceedings of the National Academy of Sciences of the United States of America
Overexpression of DNA polymerase beta sensitizes mammalian cells to 2',3'-deoxycytidine and 3'-azido-3'-deoxythymidine. Cazaux C 1997 Cancer research

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