Wang J

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Title	Authors	Year	Journal
Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase.	Wang J	2012	Biochemistry
Bidendate and tridendate metal-ion coordination states within ternary complexes of RB69 DNA polymerase.	Wang J	2012	Protein science : a publication of the Protein Society
Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue.	Wang J	2012	Biochemistry
DNA Mismatch Synthesis Complexes Provide Insights into Base Selectivity of a B Family DNA Polymerase.	Wang J	2012	Journal of the American Chemical Society
Contribution of Partial Charge Interactions and Base-Stacking to the Efficiency of Primer-Extension at and beyond Abasic Sites in DNA.	Wang J	2012	Biochemistry
Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.	Wang J	2011	Biochemistry
Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex.	Wang J	2011	Journal of the American Chemical Society
Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.	Wang J	2011	Journal of molecular biology
Insights into Base Selectivity from the 1.8 A Resolution Structure of an RB69 DNA Polymerase Ternary Complex.	Wang J	2011	Biochemistry
N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.	Wang J	2010	Bioorganic & medicinal chemistry letters
N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.	Wang J	2010	Bioorganic & medicinal chemistry letters
Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin .	Wang J	2010	Biochemistry
Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .	Wang J	2010	Biochemistry
RB69 DNA polymerase mutants with expanded nascent base-pair-binding pockets are highly efficient but have reduced base selectivity.	Wang J	2009	Biochemistry
Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile.	Wang J	2009	Antimicrobial agents and chemotherapy
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate.	Wang J	2008	Antimicrobial agents and chemotherapy
DNA polymerase-catalyzed DNA network growth.	Wang J	2008	Journal of the American Chemical Society
Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells.	Wang J	2006	Nucleic acids research
The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition.	Wang J	2006	The EMBO journal
The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination.	Wang J	2006	Biochemistry
A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity.	Wang J	2005	Proceedings of the National Academy of Sciences of the United States of America
Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site.	Wang J	2005	Biochemistry
Correction of X-ray intensities from single crystals containing lattice-translocation defects.	Wang J	2005	Acta Crystallogr D Biol Crystallogr
The activity of selected RB69 DNA polymerase mutants can be restored by manganese ions: the existence of alternative metal ion ligands used during the polymerization cycle.	Wang J	2004	Biochemistry
Pre-steady-state kinetics of RB69 DNA polymerase and its exo domain mutants: effect of pH and thiophosphoryl linkages on 3'-5' exonuclease activity.	Wang J	2004	Biochemistry
Insights into strand displacement and processivity from the crystal structure of the protein-primed DNA polymerase of bacteriophage phi29.	Wang J	2004	Molecular cell
Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP.	Wang J	2002	Cell
Structure of the replicating complex of a pol alpha family DNA polymerase.	Wang J	2001	Cell
Inhibition of HIV-1 replication by a Tat RNA-binding domain peptide analog.	Wang J	1998	Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association
Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69.	Wang J	1997	Cell
Structure of Taq polymerase with DNA at the polymerase active site.	Wang J	1996	Nature
Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions.	Wang J	1996	Biochemistry
Crystal structure of Thermus aquaticus DNA polymerase.	Wang J	1995	Nature
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.	Wang J	1994	Proceedings of the National Academy of Sciences of the United States of America
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer.	Wang J	1994	Proceedings of the National Academy of Sciences of the United States of America
Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion.	Wang J	1994	Structure (London, England : 1993)
Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I.	Wang J	1993	Cold Spring Harbor symposia on quantitative biology
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor.	Wang J	1992	Science
Role of DNA polymerase 3'----5' exonuclease activity in the bypass of aminofluorene lesions in DNA.	Wang J	1990	Carcinogenesis

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Wang J

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