N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Mitchell ML, Son JC, Lee IY, Lee CK, Kim HS, Guo H, Wang J, Hayes J, Wang M, Paul A, Lansdon EB, Chen JM, Eisenberg G, Geleziunas R, Xu L, Kim CU
Bioorganic & medicinal chemistry letters (2010), Volume 20, Page 1585
Abstract:
Polymerases:
Topics:
Structure and Structure/Function, Reverse Transcriptase
Status:
| new | topics/pols set | partial results | complete | validated |
Results:
| Polymerase | Reference | Property | Result | Context |
|---|---|---|---|---|
| HIV RT K103N | N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. | Reverse Transcriptase Activity | Yes | |
| HIV RT | N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. | Reverse Transcriptase Activity | Yes |
Entry validated by:
Structures:
