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Wood RD

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Publications:

Title Authors Year Journal
Dual role for mammalian DNA polymerase ΞΆ in maintaining genome stability and proliferative responses. Wood RD 2013 Proceedings of the National Academy of Sciences of the United States of America
Lesion bypass activity of DNA polymerase theta (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts. Wood RD 2011 Journal of molecular biology
Loss of DNA polymerase zeta enhances spontaneous tumorigenesis. Wood RD 2010 Cancer research
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Wood RD 2010 Proceedings of the National Academy of Sciences of the United States of America
Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links. Wood RD 2010 Chemical research in toxicology
Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity. Wood RD 2010 Nucleic acids research
Lack of DNA polymerase theta (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation. Wood RD 2009 Radiat Res
Low-fidelity DNA synthesis by human DNA polymerase theta. Wood RD 2008 Nucleic acids research
DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct. Wood RD 2008 DNA repair
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes. Wood RD 2007 The Journal of biological chemistry
A unique error signature for human DNA polymerase nu. Wood RD 2007 DNA repair
Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Wood RD 2006 Molecular cell
Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. Wood RD 2006 The Journal of biological chemistry
Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells. Wood RD 2006 Cancer research
High-efficiency bypass of DNA damage by human DNA polymerase Q. Wood RD 2004 The EMBO journal
POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308. Wood RD 2003 The Journal of biological chemistry
POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. Wood RD 2003 Nucleic acids research
Oxygen free radical damage to DNA. Translesion synthesis by human DNA polymerase eta and resistance to exonuclease action at cyclopurine deoxynucleoside residues. Wood RD 2001 The Journal of biological chemistry
Emerging links between hypermutation of antibody genes and DNA polymerases. Wood RD 2001 Nature reviews. Immunology
Disruption of the developmentally regulated Rev3l gene causes embryonic lethality. Wood RD 2000 Current biology : CB
Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK. Wood RD 2000 Genes & development
Differential expression of DNA polymerase epsilon in resting and activated B lymphocytes is consistent with an in vivo role in replication and not repair. Wood RD 2000 Mol Immunol
Resistance of human nucleotide excision repair synthesis in vitro to p21Cdn1. Wood RD 1998 Oncogene
Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Wood RD 1995 Cell
Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA. Wood RD 1995 Biochemistry
Structural and functional homology between mammalian DNase IV and the 5'-nuclease domain of Escherichia coli DNA polymerase I. Wood RD 1994 The Journal of biological chemistry
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