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Debyser Z

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Publications:

Title Authors Year Journal
Novel inhibitors of HIV-1 integration. Debyser Z 2004 Current drug metabolism
N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action. Debyser Z 2003 Journal of medicinal chemistry
Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives. Debyser Z 2002 Antimicrobial agents and chemotherapy
New class of HIV integrase inhibitors that block viral replication in cell culture. Debyser Z 2002 Current biology : CB
In search of authentic inhibitors of HIV-1 integration. Debyser Z 2002 Antiviral chemistry & chemotherapy
HIV-1 integration as a target for antiretroviral therapy: a review. Debyser Z 2001 Current drug targets. Infectious disorders
Polyanionic (i.e., polysulfonate) dendrimers can inhibit the replication of human immunodeficiency virus by interfering with both virus adsorption and later steps (reverse transcriptase/integrase) in the virus replicative cycle. Debyser Z 2000 Molecular pharmacology
Formation of a DNA loop at the replication fork generated by bacteriophage T7 replication proteins. Debyser Z 1998 The Journal of biological chemistry
SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus. Debyser Z 1997 Antimicrobial agents and chemotherapy
A two plasmid co-expression system in Escherichia coli for the production of virion-like reverse transcriptase of the human immunodeficiency virus type 1. Debyser Z 1996 Journal of virological methods
Chemical crosslinking of the subunits of HIV-1 reverse transcriptase. Debyser Z 1996 Protein science : a publication of the Protein Society
Characterization of HIV-1 strains isolated from patients treated with TIBO R82913. Debyser Z 1994 AIDS research and human retroviruses
New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs. Debyser Z 1994 Antimicrobial agents and chemotherapy
Coordination of leading and lagging strand DNA synthesis at the replication fork of bacteriophage T7. Debyser Z 1994 Cell
Kinetics of different human immunodeficiency virus type 1 reverse transcriptases resistant to human immunodeficiency virus type 1-specific reverse transcriptase inhibitors. Debyser Z 1993 Molecular pharmacology
Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs. Debyser Z 1993 Antimicrobial agents and chemotherapy
Specific HIV-1 reverse transcriptase inhibitors. Debyser Z 1992 Journal of enzyme inhibition
Mechanism of anti-human immunodeficiency virus action of polyoxometalates, a class of broad-spectrum antiviral agents. Debyser Z 1992 Molecular pharmacology
Allosteric inhibition of human immunodeficiency virus type 1 reverse transcriptase by tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione compounds. Debyser Z 1992 Molecular pharmacology
Differential inhibitory effects of TIBO derivatives on different strains of simian immunodeficiency virus. Debyser Z 1992 The Journal of general virology
Kinetics of inhibition of endogenous human immunodeficiency virus type 1 reverse transcription by 2',3'-dideoxynucleoside 5'-triphosphate, tetrahydroimidazo-[4,5,1-jk][1,4]-benzodiazepin-2(1H)-thion e, and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives. Debyser Z 1992 The Journal of biological chemistry
Resistance of human immunodeficiency virus type 1 reverse transcriptase to TIBO derivatives induced by site-directed mutagenesis. Debyser Z 1992 Virology
Common features in the interaction of tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives with the human immunodeficiency virus type 1 reverse transcriptase. Debyser Z 1992 Molecular pharmacology
An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives. Debyser Z 1991 Proceedings of the National Academy of Sciences of the United States of America
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