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Yan Y

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Publications:

Title Authors Year Journal
Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. Yan Y 2010 J Virol
Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants. Yan Y 2009 Bioorganic & medicinal chemistry letters
Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs). Yan Y 2008 Bioorganic & medicinal chemistry letters
The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations. Yan Y 2008 Bioorganic & medicinal chemistry letters
Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5 -chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses. Yan Y 2008 J Med Chem

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