Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors.

Abstract:

HIV/AIDS continues to be a menace to public health. Several drugs ...

Polymerases:

Topics:

Structure and Structure/Function, RNase H Activity, Reverse Transcriptase

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
HIV RT Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. Reverse Transcriptase Activity Yes
HIV RT Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. RNase H Yes

Entry validated by:

Structures:

3LP2 3LP1 3LP0