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Ohrui H

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Publications:

Title Authors Year Journal
2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine: a nucleoside reverse transcriptase inhibitor with highly potent activity against all HIV-1 strains, favorable toxic profiles and stability in plasma. Ohrui H 2006 Nucleic Acids Symp Ser (Oxf)
Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides. Ohrui H 2004 Nucleosides, nucleotides & nucleic acids
Attempt to reduce cytotoxicity by synthesizing the L-enantiomer of 4'-C-ethynyl-2'-deoxypurine nucleosides as antiviral agents against HIV and HBV. Ohrui H 2004 Antivir Chem Chemother
4'-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitro. Ohrui H 2001 Antimicrob Agents Chemother
4'-C-substituted-2'-deoxynucleosides: a family of antiretroviral agents which are potent against drug-resistant HIV variants. Ohrui H 2001 Curr Drug Targets Infect Disord
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