Ohrui H
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Publications:
Title | Authors | Year | Journal |
---|---|---|---|
2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine: a nucleoside reverse transcriptase inhibitor with highly potent activity against all HIV-1 strains, favorable toxic profiles and stability in plasma. | Ohrui H | 2006 | Nucleic Acids Symp Ser (Oxf) |
Attempt to reduce cytotoxicity by synthesizing the L-enantiomer of 4'-C-ethynyl-2'-deoxypurine nucleosides as antiviral agents against HIV and HBV. | Ohrui H | 2004 | Antivir Chem Chemother |
Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides. | Ohrui H | 2004 | Nucleosides, nucleotides & nucleic acids |
4'-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitro. | Ohrui H | 2001 | Antimicrob Agents Chemother |
4'-C-substituted-2'-deoxynucleosides: a family of antiretroviral agents which are potent against drug-resistant HIV variants. | Ohrui H | 2001 | Curr Drug Targets Infect Disord |