A Triad Interaction in the Fingers Subdomain of DNA Polymerase Beta Controls Polymerase Activity |
Sweasy JB, Jaeger J, Murphy DL |
2011 |
Determination of lysine pK values using [5-13C]lysine: application to the lyase domain of DNA Pol beta. |
Gao G, Prasad R, Lodwig SN, Unkefer CJ, Beard WA, Wilson SH, London RE |
2006 |
Quantum mechanics/molecular mechanics investigation of the chemical reaction in Dpo4 reveals water-dependent pathways and requirements for active site reorganization. |
Wang Y, Schlick T |
2008 |
Computer simulation of the chemical catalysis of DNA polymerases: discriminating between alternative nucleotide insertion mechanisms for T7 DNA polymerase. |
Florián J, Goodman MF, Warshel A |
2003 |
A DNA polymerase with specificity for five base pairs. |
Showalter AK, Tsai MD |
2001 |
A water-mediated and substrate-assisted catalytic mechanism for Sulfolobus solfataricus DNA polymerase IV. |
Wang L, Yu X, Hu P, Broyde S, Zhang Y |
2007 |
(+)-Myristinin A, a naturally occurring DNA polymerase beta inhibitor and potent DNA-damaging agent. |
Maloney DJ, Deng JZ, Starck SR, Gao Z, Hecht SM |
2005 |
Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase. |
Huang H, Stivers JT, Greenberg MM |
2009 |
A pre-RNA candidate revisited: both enantiomers of flexible nucleoside triphosphates are DNA polymerase substrates. |
Heuberger BD, Switzer C |
2008 |
Attomole detection of mesophilic DNA polymerase products by nanoparticle-enhanced surface plasmon resonance imaging on glassified gold surfaces. |
Gifford LK, Sendroiu IE, Corn RM, Lupták A |
2010 |
A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine. |
Goodwin KD, Lewis MA, Tanious FA, Tidwell RR, Wilson WD, Georgiadis MM, Long EC |
2006 |
Fidelity discrimination in DNA polymerase beta: differing closing profiles for a mismatched (G:A) versus matched (G:C) base pair. |
Radhakrishnan R, Schlick T |
2005 |
Expanding the substrate repertoire of a DNA polymerase by directed evolution. |
Fa M, Radeghieri A, Henry AA, Romesberg FE |
2004 |
Opposed steric constraints in human DNA polymerase beta and E. coli DNA polymerase I. |
Di Pasquale F, Fischer D, Grohmann D, Restle T, Geyer A, Marx A |
2008 |
Differential minor groove interactions between DNA polymerase and sugar backbone of primer and template strands. |
Summerer D, Marx A |
2002 |
Irreversible inhibition of DNA polymerase beta by an oxidized abasic lesion. |
Guan L, Greenberg MM |
2010 |
Replacing 32 proline residues by a noncanonical amino acid results in a highly active DNA polymerase. |
Holzberger B, Marx A |
2010 |
Halogenated beta,gamma-methylene- and ethylidene-dGTP-DNA ternary complexes with DNA polymerase beta: structural evidence for stereospecific binding of the fluoromethylene analogues. |
Batra VK, Pedersen LC, Beard WA, Wilson SH, Kashemirov BA, Upton TG, Goodman MF, McKenna CE |
2010 |
Selective recognition of unnatural imidazopyridopyrimidine:naphthyridine base pairs consisting of four hydrogen bonds by the Klenow fragment. |
Minakawa N, Ogata S, Takahashi M, Matsuda A |
2009 |
Reaction mechanism of the epsilon subunit of E. coli DNA polymerase III: insights into active site metal coordination and catalytically significant residues. |
Cisneros GA, Perera L, Schaaper RM, Pedersen LC, London RE, Pedersen LG, Darden TA |
2009 |
Implications of active site constraints on varied DNA polymerase selectivity. |
Strerath M, Cramer J, Restle T, Marx A |
2002 |
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly. |
Yang L, Arora K, Beard WA, Wilson SH, Schlick T |
2004 |
Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents. |
Wu T, Froeyen M, Kempeneers V, Pannecouque C, Wang J, Busson R, De Clercq E, Herdewijn P |
2005 |
Quantum dot FRET biosensors that respond to pH, to proteolytic or nucleolytic cleavage, to DNA synthesis, or to a multiplexing combination. |
Suzuki M, Husimi Y, Komatsu H, Suzuki K, Douglas KT |
2008 |
(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta. |
McKenna CE, Kashemirov BA, Upton TG, Batra VK, Goodman MF, Pedersen LC, Beard WA, Wilson SH |
2007 |
DNA polymerase-mediated DNA synthesis on a TNA template. |
Chaput JC, Ichida JK, Szostak JW |
2003 |
DNA polymerase-catalyzed DNA network growth. |
Keller S, Wang J, Chandra M, Berger R, Marx A |
2008 |
Enzymatic synthesis of phosphoroselenoate DNA using thymidine 5'-(alpha-P-seleno)triphosphate and DNA polymerase for X-ray crystallography via MAD. |
Carrasco N, Huang Z |
2004 |
A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution. |
Cockroft SL, Chu J, Amorin M, Ghadiri MR |
2008 |
DNA polymerase beta catalysis: are different mechanisms possible? |
Alberts IL, Wang Y, Schlick T |
2007 |
Synthesis, DNA polymerase incorporation, and enzymatic phosphate hydrolysis of formamidopyrimidine nucleoside triphosphates. |
Imoto S, Patro JN, Jiang YL, Oka N, Greenberg MM |
2006 |
Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker. |
Marquez VE, Ben-Kasus T, Barchi JJ, Green KM, Nicklaus MC, Agbaria R |
2004 |
Processive replication of single DNA molecules in a nanopore catalyzed by phi29 DNA polymerase. |
Lieberman KR, Cherf GM, Doody MJ, Olasagasti F, Kolodji Y, Akeson M |
2010 |
Specific nucleotide binding and rebinding to individual DNA polymerase complexes captured on a nanopore. |
Hurt N, Wang H, Akeson M, Lieberman KR |
2009 |
Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex. |
Xia S, Konigsberg WH, Wang J |
2011 |
A triad interaction in the fingers subdomain of DNA polymerase beta controls polymerase activity. |
Murphy DL, Jaeger J, Sweasy JB |
2011 |
Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV. |
Banerjee S, Brown KL, Egli M, Stone MP |
2011 |
β,γ-CHF- and β,γ-CHCl-dGTP diastereomers: synthesis, discrete 31P NMR signatures and absolute configurations of new stereochemical probes for DNA polymerases. |
Wu Y, Zakharova VM, Kashemirov BA, Goodman MF, Batra VK, Wilson SH, McKenna CE |
2012 |
Unfavorable electrostatic and steric interactions in DNA polymerase β E295K mutant interfere with the enzyme's pathway. |
Li Y, Gridley CL, Jaeger J, Sweasy JB, Schlick T |
2012 |
A nucleotide analogue induced gain of function corrects the error-prone nature of human DNA polymerase iota. |
Ketkar A, Zafar MK, Banerjee S, Marquez VE, Egli M, Eoff RL |
2012 |
Multi-domain Protein Solves the Folding Problem by Multi-funnel Combined Landscape: Theoretical Investigation of a Y-Family DNA Polymerase. |
Wang Y, Chu X, Suo Z, Wang E, Wang J |
2012 |
Single-molecule Förster resonance energy transfer reveals an innate fidelity checkpoint in DNA polymerase I. |
Berezhna SY, Gill JP, Lamichhane R, Millar DP |
2012 |
Structures of KlenTaq DNA polymerase caught while incorporating C5-modified pyrimidine and C7-modified 7-deazapurine nucleoside triphosphates. |
Bergen K, Steck AL, Strütt S, Baccaro A, Welte W, Diederichs K, Marx A |
2012 |
DNA Mismatch Synthesis Complexes Provide Insights into Base Selectivity of a B Family DNA Polymerase. |
Xia S, Wang J, Konigsberg WH |
2012 |
The molecular basis of resilience to the effect of the Lys103Asn mutation in non-nucleoside HIV-1 reverse transcriptase inhibitors studied by targeted molecular dynamics simulations. |
Rodríguez-Barrios F, Balzarini J, Gago F |
2005 |
Dynamics of the translocation step measured in individual DNA polymerase complexes. |
Lieberman KR, Dahl JM, Mai AH, Akeson M, Wang H |
2012 |
Amino acid substitution in the active site of DNA polymerase β explains the energy barrier of the nucleotidyl transfer reaction. |
Batra VK, Perera L, Lin P, Shock DD, Beard WA, Pedersen LC, Pedersen LG, Wilson SH |
2013 |
Dynamics of site switching in DNA polymerase. |
Lamichhane R, Berezhna SY, Gill JP, Van der Schans EJ, Millar DP |
2013 |
Snapshot of a DNA polymerase while incorporating two consecutive C5-modified nucleotides. |
Obeid S, Bußkamp H, Welte W, Diederichs K, Marx A |
2013 |