Touching the heart of HIV-1 drug resistance: the fingers close down on the dNTP at the polymerase active site. |
Sarafianos SG, Das K, Ding J, Boyer PL, Hughes SH, Arnold E |
1999 |
Structural elucidation of the binding and inhibitory properties of lanthanide (III) ions at the 3'-5' exonucleolytic active site of the Klenow fragment. |
Brautigam CA, Aschheim K, Steitz TA |
1999 |
Elucidation of the metal-binding properties of the Klenow fragment of Escherichia coli polymerase I and bacteriophage T4 DNA polymerase by lanthanide(III) luminescence spectroscopy. |
Frey MW, Frey ST, Horrocks WD, Kaboord BF, Benkovic SJ |
1996 |
Structural insights into DNA polymerase beta fidelity: hold tight if you want it right. |
Beard WA, Wilson SH |
1998 |
DNA polymerase template interactions probed by degenerate isosteric nucleobase analogs. |
Paul N, Nashine VC, Hoops G, Zhang P, Zhou J, Bergstrom DE, Davisson VJ |
2003 |
Identification of a small molecule that inhibits herpes simplex virus DNA Polymerase subunit interactions and viral replication. |
Pilger BD, Cui C, Coen DM |
2004 |
Hydrophobic amino acid and single-atom substitutions increase DNA polymerase selectivity. |
Rudinger NZ, Kranaster R, Marx A |
2007 |
Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase. |
Loregian A, Coen DM |
2006 |
Probing interactions between HIV-1 reverse transcriptase and its DNA substrate with backbone-modified nucleotides. |
Marx A, Spichty M, Amacker M, Schwitter U, Hübscher U, Bickle TA, Maga G, Giese B |
1999 |
A synthetic substrate of DNA polymerase deviating from the bases, sugar, and leaving group of canonical deoxynucleoside triphosphates. |
Jang MY, Song XP, Froeyen M, Marlière P, Lescrinier E, Rozenski J, Herdewijn P |
2013 |