Chemical research in toxicology

(Chem Res Toxicol) ISSNs: , 1520-5010

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Title	Authors	Year
Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links.	Yamanaka K, Minko IG, Takata K, Kolbanovskiy A, Kozekov ID, Wood RD, Rizzo CJ, Lloyd RS	2010
Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).	Christov PP, Petrova KV, Shanmugam G, Kozekov ID, Kozekova A, Guengerich FP, Stone MP, Rizzo CJ	2010
Polymerization past the N2-isopropylguanine and the N6-isopropyladenine DNA lesions with the translesion synthesis DNA polymerases eta and iota and the replicative DNA polymerase alpha.	Perrino FW, Harvey S, Blans P, Gelhaus SL, Lacourse WR, Fishbein JC	2005
The N2-ethylguanine and the O6-ethyl- and O6-methylguanine lesions in DNA: contrasting responses from the "bypass" DNA polymerase eta and the replicative DNA polymerase alpha.	Perrino FW, Blans P, Harvey S, Gelhaus SL, McGrath C, Akman SA, Jenkins GS, Lacourse WR, Fishbein JC	2003
Replication past the N5-methyl-formamidopyrimidine lesion of deoxyguanosine by DNA polymerases and an improved procedure for sequence analysis of in vitro bypass products by mass spectrometry.	Christov PP, Angel KC, Guengerich FP, Rizzo CJ	2009
Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations.	Wang L, Wu M, Yan SF, Patel DJ, Geacintov NE, Broyde S	2005
Molecular dynamics of a food carcinogen-DNA adduct in a replicative DNA polymerase suggest hindered nucleotide incorporation and extension.	Zhang L, Shapiro R, Broyde S	2005
Replication of a site-specific trans-8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B(1) adduct by the exonuclease deficient klenow fragment of DNA polymerase I.	Johnston DS, Stone MP	2000
Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the NarI recognition sequence by prokaryotic DNA polymerases.	Stover JS, Chowdhury G, Zang H, Guengerich FP, Rizzo CJ	2006
Translesion synthesis across polycyclic aromatic hydrocarbon diol epoxide adducts of deoxyadenosine by Sulfolobus solfataricus DNA polymerase Dpo4.	Zang H, Chowdhury G, Angel KC, Harris TM, Guengerich FP	2006
Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine.	Goodenough AK, Kozekov ID, Zang H, Choi JY, Guengerich FP, Harris TM, Rizzo CJ	2005
Kinetics of nucleotide incorporation opposite polycyclic aromatic hydrocarbon-DNA adducts by processive bacteriophage T7 DNA polymerase.	Zang H, Harris TM, Guengerich FP	2005
Kinetic Analysis of the Bypass of a Bulky DNA Lesion Catalyzed by Human Y-family DNA Polymerases.	Sherrer SM, Sanman LE, Xia CX, Bolin ER, Malik CK, Efthimiopoulos G, Basu AK, Suo Z	2012
Low fidelity bypass of O<sup>2</sup>-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model polymerases.	A S PG, Krishnegowda G, Suo Z, Amin SG, Spratt TE	2012
Species-specific, P450- and sulfotransferase-mediated novel ring contraction of a naphthyridine-N-oxide compound in cynomolgus monkey.	Daniels JS, Espina R, Cao K, Yuan H, Lin J, Diamond S, Johnson B, Rodgers J, Prakash S, Unger S, Christ D, Miwa G, Gan LS, Mutlib A	2007
Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family.	Minko IG, Yamanaka K, Kozekov ID, Kozekova A, Indiani C, O'Donnell ME, Jiang Q, Goodman MF, Rizzo CJ, Lloyd RS	2008
1,N2-Etheno-2'-deoxyguanosine adopts the syn conformation about the glycosyl bond when mismatched with deoxyadenosine.	Shanmugam G, Kozekov ID, Guengerich FP, Rizzo CJ, Stone MP	2011
The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro.	Christov PP, Chowdhury G, Garmendia CA, Wang F, Stover JS, Elmquist CE, Kozekova A, Angel KC, Turesky RJ, Stone MP, Guengerich FP, Rizzo CJ	2010
Polymerase blockage and misincorporation of dNTPs opposite the ethylene dibromide-derived DNA adducts S-[2-(N7-guanyl)ethyl]glutathione, S-[2-(N2-guanyl)ethyl]glutathione, and S-[2-(O6-guanyl)ethyl]glutathione.	Kim MS, Guengerich FP	1998
Identification of an Unfolding Intermediate for a DNA Lesion Bypass Polymerase.	Sherrer SM, Maxwell BA, Pack LR, Fiala KA, Fowler JD, Zhang J, Suo Z	2012
Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV.	Banerjee S, Christov PP, Kozekova A, Rizzo CJ, Egli M, Stone MP	2012
Accurate and Efficient Bypass of 8,5'-Cyclopurine-2'-Deoxynucleosides by Human and Yeast DNA Polymerase η	Swanson AL, Wang J, Wang Y	2012
Effects of N2-Alkylguanine, O6-Alkylguanine, and Abasic Lesions on DNA Binding and Bypass Synthesis by the Euryarchaeal B-family DNA Polymerase Vent (exo-).	Lim S, Song I, Guengerich FP, Choi JY	2012
DNA Polymerase β Gap-filling Translesion DNA Synthesis.	Chary P, Beard WA, Wilson SH, Lloyd RS	2012
Mutagenic bypass of 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) by DNA polymerase κ in human cells.	Kamiya H, Kurokawa M	2012
In-vitro replication studies on o(2)-methylthymidine and o(4)-methylthymidine.	Andersen N, Wang J, Wang P, Jiang Y, Wang Y	2012
Mutagenesis induced by oxidized DNA precursors: roles of Y family DNA polymerases in Escherichia coli.	Satou K, Yamada M, Nohmi T, Harashima H, Kamiya H	2005
Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity.	Ketkar A, Zafar MK, Maddukuri L, Yamanaka K, Banerjee S, Egli M, Choi JY, Lloyd RS, Eoff RL	2013
Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4.	Shanmugam G, Minko IG, Banerjee S, Christov PP, Kozekov ID, Rizzo CJ, Lloyd RS, Egli M, Stone MP	2013

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