Human Pol nu

From H. sapiens (aliases:POLN, POL4P) (genes: POLN)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Human Pol nu.


At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.


If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.


All references that refer to this Polymerase are listed with their topics and paper's title in the References table.


All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

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Human Pol nu is a family A enzyme from H. sapiens.

Selected Properties for Human Pol nu:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (2) no data no data 3.5e-03 errors/bp (1) no data
Year Authors Title Results by property
2011 Mercedes E Arana, Olga Potapova, Thomas A Kunkel, Catherine M Joyce Kinetic analysis of the unique error ...
2010 Kei-ichi Takata, Mercedes E Arana, Masayuki Seki, Thomas A Kunkel, Richard D Wood Evolutionary conservation of residues...
2010 Mercedes E Arana, Gary K Powell, Lori L Edwards, Thomas A Kunkel, Robert M Petrovich Refolding active human DNA polymerase...
2010 Mark D Sutton Coordinating DNA polymerase traffic d...
2009 Laura Zietlow, Leigh Anne Smith, Mika Bessho, Tadayoshi Bessho Evidence for the involvement of human...
2007 Mercedes E Arana, Kei-ichi Takata, Miguel Garcia-Diaz, Richard D Wood, Thomas A Kunkel A unique error signature for human DN... Cloned or native,Tagged,Tag Name,3-5' exo,Nucleotide Substitution Rate,All properties
2006 Kei-ichi Takata, Tatsuhiko Shimizu, Shigenori Iwai, Richard D Wood Human DNA polymerase N (POLN) is a lo... Processivity,Nick Extension,Strand Displacement,3-5' exo,Molecular Weight,Amino Acids Contacting NTP,Template lesions,All properties

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