Human Pol zeta

From H. sapiens (aliases:Rev3) (genes: REV3L)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Human Pol zeta.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Human Pol zeta is a family B enzyme from H. sapiens.

Selected Properties for Human Pol zeta:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data 5.0e-04 errors/bp (1)
Year Authors Title Results by property
S Sharma, CM Helchowski, CE Canman The roles of DNA polymerase ζ and the...
2013 Ting-Yan Shi, Li Yang, Gong Yang, Xiao-Yu Tu, Xiaohua Wu, Xi Cheng, Qingyi Wei DNA polymerase ζ as a potential bioma...
2012 Jundong Zhou, Shuyu Zhang, Ling Xie, Pengfei Liu, Fang Xie, Jinchang Wu, Jianping Cao, Wei-Qun Ding Overexpression of DNA polymerase iota...
2012 Sotaro Kikuchi, Kodai Hara, Toshiyuki Shimizu, Mamoru Sato, Hiroshi Hashimoto Structural basis of recruitment of DN...
2012 S Sharma, Nicholas A Shah, Ariell M Joiner, Katelyn H Roberts, CE Canman DNA polymerase ζ is a major determina...
2011 S Sharma, JK Hicks, CL Chute, JR Brennan, JY Ahn, TW Glover, CE Canman REV1 and polymerase {zeta} facilitate...
2010 Jung-Hoon Yoon, G Bhatia, Satya Prakash, Louise Prakash Error-free replicative bypass of thym...
2010 Mark D Sutton Coordinating DNA polymerase traffic d...
2010 TheVinh Ho, OrlandoD Schärer Translesion DNA synthesis polymerases...
2010 AbelCS Chun, Dong-Yan Jin Ubiquitin-dependent regulation of tra...
2009 Kazuya Satou, Mika Hori, Kazuaki Kawai, Hiroshi Kasai, Hideyoshi Harashima, Hiroyuki Kamiya Involvement of specialized DNA polyme...
2009 Cai-hua Xi, Jin Hu, Hui-bo Wang, Shu-yu Zhang, Da-lu Ru [Expression study of DNA translesion ...
2009 Kei-ichi Takata, RichardD Wood Bypass specialists operate together.
2009 Sigal Shachar, Omer Ziv, Sharon Avkin, Sheera Adar, John P Wittschieben, Thomas Reissner, Stephen Chaney, Errol C Friedberg, Zhengqiang Wang, Thomas Carell, Nicholas E Geacintov, Zvi Livneh Two-polymerase mechanisms dictate err...
2009 Lauren S Waters, Brenda K Minesinger, Mary Ellen Wiltrout, Sanjay D'Souza, Rachel V Woodruff, Graham C Walker Eukaryotic translesion polymerases an...
2008 J-M Brondello, Marie-Jeanne Pillaire, C Rodriguez, P-A Gourraud, Janick Selves, Christophe Cazaux, J Piette Novel evidences for a tumor suppresso...
2008 Quentin Gueranger, Anne Stary, Saïd Aoufouchi, Ahmad Faili, Alain Sarasin, Claude-Agnès Reynaud, Jean-Claude Weill Role of DNA polymerases eta, iota and...
2008 GregoryN Gan, JohnP Wittschieben, BirgitteØ Wittschieben, RichardD Wood DNA polymerase zeta (pol zeta) in hig...
2007 PriscillaH Fernandes, RStephen Lloyd Mutagenic bypass of the butadiene-der...
2006 Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Hoogsteen base pair formation promote...
2002 M Todd Washington, Robert E Johnson, Louise Prakash, Satya Prakash Human DINB1-encoded DNA polymerase ka...
2001 Patricia J Gearhart, Richard D Wood Emerging links between hypermutation ... Associated condition,Overall Error Rate,All properties
2001 Marilyn Diaz, M F Flajnik, N Klinman Evolution and the molecular basis of ...
2001 H Zan, A Komori, Zhongjie Li, A Cerutti, A Schaffer, M F Flajnik, Marilyn Diaz, P Casali The translesion DNA polymerase zeta p...
2001 Christopher W Lawrence, Veronica M Maher Mutagenesis in eukaryotes dependent o...
2001 Christopher W Lawrence, Veronica M Maher Eukaryotic mutagenesis and translesio...
2000 James E Cleaver Common pathways for ultraviolet skin ...
2000 Robert E Johnson, M Todd Washington, Lajos Haracska, Satya Prakash, Louise Prakash Eukaryotic polymerases iota and zeta ...
2000 John P Wittschieben, M K Shivji, E Lalani, M A Jacobs, Federica Marini, Patricia J Gearhart, I Rosewell, G Stamp, Richard D Wood Disruption of the developmentally reg...
1999 W Lin, Xiaoming Wu, Zhengqiang Wang A full-length cDNA of hREV3 is predic...
1998 Peter E M Gibbs, William Glenn McGregor, Veronica M Maher, P Nisson, Christopher W Lawrence A human homolog of the Saccharomyces ...

Using Polbase tables:

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