Human REV1
Welcome to the Polymerase Page
This page presents all the information in Polbase for Human REV1.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
REV1 is has polymerase activity in isolation, but complexes with REV7 to form pol zeta.
Selected Properties for Human REV1: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| no data | no data | no data | no data | no data |
- References (10)
- Structures (1)
- Sequences (0)
- Mutants (0)...
- Formulations (0)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| S Sharma, CM Helchowski, CE Canman | The roles of DNA polymerase ζ and the... | ||
| 2012 | S Sharma, Nicholas A Shah, Ariell M Joiner, Katelyn H Roberts, CE Canman | DNA polymerase ζ is a major determina... | |
| 2012 | Shanen M Sherrer, Laura E Sanman, Cynthia X Xia, Eric R Bolin, Chanchal K Malik, Georgia Efthimiopoulos, Ashis K Basu, Zucai Suo | Kinetic Analysis of the Bypass of a B... | |
| 2012 | Shanen M Sherrer, DJ Taggart, Lindsey R Pack, Chanchal K Malik, Ashis K Basu, Zucai Suo | Quantitative analysis of the mutageni... | |
| 2012 | Yulia Pustovalova, Irina Bezsonova, Dmitry M Korzhnev | The C-terminal domain of human Rev1 c... | |
| 2012 | Sotaro Kikuchi, Kodai Hara, Toshiyuki Shimizu, Mamoru Sato, Hiroshi Hashimoto | Structural basis of recruitment of DN... | |
| 2011 | S Sharma, JK Hicks, CL Chute, JR Brennan, JY Ahn, TW Glover, CE Canman | REV1 and polymerase {zeta} facilitate... | |
| 2010 | Mark D Sutton | Coordinating DNA polymerase traffic d... | |
| 2009 | Kazuya Satou, Mika Hori, Kazuaki Kawai, Hiroshi Kasai, Hideyoshi Harashima, Hiroyuki Kamiya | Involvement of specialized DNA polyme... | |
| 2008 | Jeong-Yun Choi, F Peter Guengerich | Kinetic analysis of translesion synth... |
Predicted Structure Model
This AlphaFold DB model is predicted and not an experimentally determined structure. View AlphaFold DB entry Download predicted model (.pdb)
Confidence legend (pLDDT)
AlphaFold DB colors residues by predicted confidence. Use high-confidence regions for structural context and treat low-confidence regions cautiously.
- Very high (pLDDT > 90) Backbone and side chains are usually reliable.
- Confident (pLDDT 70-90) Overall fold is usually reliable, but some local detail may shift.
- Low (pLDDT 50-70) Use with caution; this region may be flexible or uncertain.
- Very low (pLDDT < 50) Often disordered or not confidently placed.
Protein information: Uniprot Q9UBZ9 search for Human REV1 at UniProt
Sequence information: NCBI nucleotides European nucleotide archive
Predicted structure: AlphaFold DB entry AF-Q9UBZ9-F1