Human REV1

From H. sapiens
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Human REV1.


At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.


If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.


All references that refer to this Polymerase are listed with their topics and paper's title in the References table.


All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

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Human REV1 is a family Non Pol enzyme from H. sapiens.

REV1 is has polymerase activity in isolation, but complexes with REV7 to form pol zeta.

Selected Properties for Human REV1:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
S Sharma, CM Helchowski, CE Canman The roles of DNA polymerase ζ and the...
2012 S Sharma, Nicholas A Shah, Ariell M Joiner, Katelyn H Roberts, CE Canman DNA polymerase ζ is a major determina...
2012 Shanen M Sherrer, Laura E Sanman, Cynthia X Xia, Eric R Bolin, Chanchal K Malik, Georgia Efthimiopoulos, Ashis K Basu, Zucai Suo Kinetic Analysis of the Bypass of a B...
2012 Shanen M Sherrer, DJ Taggart, Lindsey R Pack, Chanchal K Malik, Ashis K Basu, Zucai Suo Quantitative analysis of the mutageni...
2012 Yulia Pustovalova, Irina Bezsonova, Dmitry M Korzhnev The C-terminal domain of human Rev1 c...
2012 Sotaro Kikuchi, Kodai Hara, Toshiyuki Shimizu, Mamoru Sato, Hiroshi Hashimoto Structural basis of recruitment of DN...
2011 S Sharma, JK Hicks, CL Chute, JR Brennan, JY Ahn, TW Glover, CE Canman REV1 and polymerase {zeta} facilitate...
2010 Mark D Sutton Coordinating DNA polymerase traffic d...
2009 Kazuya Satou, Mika Hori, Kazuaki Kawai, Hiroshi Kasai, Hideyoshi Harashima, Hiroyuki Kamiya Involvement of specialized DNA polyme...
2008 Jeong-Yun Choi, F Peter Guengerich Kinetic analysis of translesion synth...

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