RB69 D222AD327A

From Bacteriophage RB69 (aliases:RB69 exo-)
show help

Welcome to the Polymerase Page

This page presents all the information in Polbase for RB69 D222AD327A.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Mutant of: RB69 (D222A,D327A)

RB69 D222AD327A is a family B enzyme from Bacteriophage RB69.

Selected Properties for RB69 D222AD327A:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (1) no data 5.2e+02 Mutation frequency (relative to WT) (1) 4.9e+02-2.6e+03 Mutation frequency (relative to WT) (3) no data
Year Authors Title Results by property
2008 Usharani Subuddhi, Matthew Hogg, Linda J Reha-Krantz Use of 2-aminopurine fluorescence to ... 3-5' exo,All properties
2006 Haijiang Zhang, Chanu Rhee, Anna Bebenek, John W Drake, Jianhong Wang, William H Konigsberg The L561A substitution in the nascent...
2005 Guangwei Yang, Jianhong Wang, William H Konigsberg Base selectivity is impaired by mutan...
2005 John W Drake, Anna Bebenek, Grace E Kissling, Shyamal Peddada Clusters of mutations from transient ...
2003 Siyang Sun, Yousif Shamoo Biochemical characterization of inter... Kd,All properties
2002 Anna Bebenek, Geraldine T Carver, Holly Kloos Dressman, Farid A Kadyrov, Joseph K Haseman, Vasiliy M Petrov, William H Konigsberg, Jim D Karam, John W Drake Dissecting the fidelity of bacterioph...
2001 M C Franklin, Jianhong Wang, Thomas A Steitz Structure of the replicating complex ...
2001 Anna Bebenek, Holly Kloos Dressman, Geraldine T Carver, S Ng , Vasiliy M Petrov, Guangwei Yang, William H Konigsberg, Jim D Karam, John W Drake Interacting fidelity defects in the r... Frameshift Error Rate,Nucleotide Substitution Rate,All properties
1997 Holly Kloos Dressman, C C Wang, Jim D Karam, John W Drake Retention of replication fidelity by ... Nucleotide Substitution Rate,All properties

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.