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HIV RT K65R

From HIV
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Welcome to the Polymerase Page

This page presents all the information in Polbase for HIV RT K65R.

Mutants:

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Structures/Sequence:

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Mutant of: HIV RT (K65R)

HIV RT K65R is a family RT enzyme from HIV. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:288|codon:AAA>AGA|drugs:1592U89 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:289|codon:AAA>AGA|drugs:3TC "From the Los Alamos National Labs HIV Mutant database (now offline):|id:290|codon:AAA>AGA|drugs:dOTC "From the Los Alamos National Labs HIV Mutant database (now offline):|id:291|codon:AAA>AGA|drugs:d-d4FC "From the Los Alamos National Labs HIV Mutant database (now offline):|id:292|codon:AAA>AGA|drugs:d4T "From the Los Alamos National Labs HIV Mutant database (now offline):|id:293|codon:AAA>AGA|drugs:d4T "From the Los Alamos National Labs HIV Mutant database (now offline):|id:294|codon:AAA>AGA|drugs:ddC "From the Los Alamos National Labs HIV Mutant database (now offline):|id:295|codon:AAA>AGA|drugs:ddI From the Los Alamos National Labs HIV Mutant database (now offline):|id:296|codon:AAA>AGA|drugs:DXG|class:Nucleoside RT Inhibitor (NRTI)|notes:8.7-fold resistance "From the Los Alamos National Labs HIV Mutant database (now offline):|id:297|codon:AAA>AGA|drugs:PMEA "From the Los Alamos National Labs HIV Mutant database (now offline):|id:298|codon:AAA>AGA|drugs:PMPA

Selected Properties for HIV RT K65R:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2009 Kalyan Das, Rajiv P Bandwar, Kirsten L White, Joy Y Feng, Stefan G Sarafianos, Steven Tuske, Xiongying Tu, Arthur D Clark, Paul L Boyer, Xiaorong Hou, Barbara L Gaffney, Roger A Jones, Michael D Miller, Stephen H Hughes, Edward Arnold Structural basis for the role of the ... RT,All properties
2003 Romas Geleziunas, Karen Gallagher, Hangchun Zhang, Lee Bacheler, Sena Garber, Jing-Tao Wu, Guoen Shi, Michael J Otto, Raymond F Schinazi, Susan Erickson-Viitanen HIV-1 resistance profile of the novel...
2003 J Gerardo García-Lerma, Hamish MacInnes, Diane Bennett, Patrick Reid, Soumya Nidtha, Hillard Weinstock, Jonathan E Kaplan, Walid Heneine A novel genetic pathway of human immu...
2000 Holly Z Bazmi, J L Hammond, S C Cavalcanti, Chung K Chu, Raymond F Schinazi, John W Mellors In vitro selection of mutations in th...
2000 D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando Drug resistance and drug combination ...
1999 Mark A. Wainberg, Michael D Miller, Yudong Quan, H Salomon, A S Mulato, P D Lamy, Nicolas A Margot, K E Anton, J M Cherrington In vitro selection and characterizati...
1997 M Tisdale, T Alnadaf, D Cousens Combination of mutations in human imm...
1996 Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak The K65R mutation confers increased D... RT,Cloned or native,Full length or truncated,Extension from RNA primer,All properties
1996 A Foli, K M Sogocio, B Anderson, M Kavlick, M W Saville, Mark A. Wainberg, Z Gu, J M Cherrington, Hiroyuki Mitsuya, R Yarchoan In vitro selection and molecular char...
1994 Z Gu, Q Gao, H Fang, H Salomon, Michael A. Parniak, E Goldberg, J Cameron, Mark A. Wainberg Identification of a mutation at codon...
1994 D Zhang, A M Caliendo, J J Eron, K M DeVore, J C Kaplan, M S Hirsch, R T D'Aquila Resistance to 2',3'-dideoxycytidine c...

Version:20251120

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