ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID, XVI. OLIGONUCLEOTIDES AS TEMPLATES AND THE MECHANISM OF THEIR REPLICATION.

Polymerases:

Topics:

Kinetic Parameters, Enzyme Substrate Interactions, Modulators/Inhibitors, Structure and Structure/Function

Note:

Paper Discusses AT-rich DNA's priming of dAT synthesis and the kinetic components therein.

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
Eco Pol I Kornberg A1964 Other Important Residues deoxyadenylate and deoxythymidylate [(AT)3 to (AT)7]
Eco Pol I Kornberg A1964 Percent/Fold Effect 50 % decrease Reaction: Nucleotide incorporation; Substrate: dNTPs; Experimental conditions: Temp (20°C)

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