On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation.




Nucleotide Incorporation, Fidelity, Exonuclease Activity, Source / Purification

One line summary:

The tsL88 (G694S) DNA polymerase had reduced accuracy of nucleotide incorporation.


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Polymerase Reference Property Result Context
T4 Hershfield MS1973 3-5' Exonuclease (proofreading) Yes
T4 Hershfield MS1973 Cloned or native Native organism
T4 Hershfield MS1973 Tagged No
T4 Hershfield MS1973 Full length or truncated Full length

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