The Journal of biological chemistry

(J Biol Chem) ISSNs: , 1083-351X

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Title	Authors	Year
Nuclease activity in a fragment of bacteriophage T4 deoxyribonucleic acid polymerase induced by the amber mutant am B22.	Nossal NG, Hershfield MS	1971
The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an ajar intermediate conformation in the nucleotide selection mechanism	Wu E, Beese L	2011
Hydrolysis of template and newly synthesized deoxyribonucleic acid by the 3' to 5' exonuclease activity of the T4 deoxyribonucleic acid polymerase.	Hershfield MS, Nossal NG	1972
RNA primer handoff in bacteriophage T4 DNA replication: the role of single-stranded DNA-binding protein and polymerase accessory proteins.	Nelson SW, Kumar R, Benkovic SJ	2008
Comparative kinetics of nucleotide analog incorporation by vent DNA polymerase.	Gardner AF, Joyce CM, Jack WE	2004
Bypass of a nick by the replisome of bacteriophage T7.	Zhu B, Lee SJ, Richardson CC	2011
On the exonuclease activity of phage T4 deoxyribonucleic acid polymerase.	Huang WM, Lehman IR	1972
Functional analysis of HIV-1 reverse transcriptase amino acids involved in resistance to multiple nonnucleoside inhibitors.	Sardana VV, Emini EA, Gotlib L, Graham DJ, Lineberger DW, Long WJ, Schlabach AJ, Wolfgang JA, Condra JH	1992
Characterization of a DNA polymerase from the hyperthermophile archaea Thermococcus litoralis. Vent DNA polymerase, steady state kinetics, thermal stability, processivity, strand displacement, and exonuclease activities.	Kong H, Kucera RB, Jack WE	1993
Purification and properties of wild-type and exonuclease-deficient DNA polymerase II from Escherichia coli.	Cai H, Yu H, McEntee K, Kunkel TA, Goodman MF	1995
Homology between mammalian DNA polymerase beta and terminal deoxynucleotidyltransferase.	Matsukage A, Nishikawa K, Ooi T, Seto Y, Yamaguchi M	1987
Immunological comparison of purified DNA polymerase alpha from embryos of Drosophila melanogaster with forms of the enzyme present in vivo.	Sauer B, Lehman IR	1982
Effect of phosphorothioate homo-oligodeoxynucleotides on herpes simplex virus type 2-induced DNA polymerase.	Gao WY, Stein CA, Cohen JS, Dutschman GE, Cheng YC	1989
DNA polymerase III from Saccharomyces cerevisiae. II. Inhibitor studies and comparison with DNA polymerases I and II.	Burgers PM, Bauer GA	1988
Reactions at the polymerase active site that contribute to the fidelity of Escherichia coli DNA polymerase I (Klenow fragment).	Joyce CM, Sun XC, Grindley ND	1992
Biochemical properties of Saccharomyces cerevisiae DNA polymerase IV.	Bebenek K, Garcia-Diaz M, Patishall SR, Kunkel TA	2005
Thioredoxin reductase-dependent insulin disulfide reduction by phage T7 DNA polymerase reflects dissociation of the enzyme into subunits.	Slaby I, Holmgren A	1989
Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus.	Weiser T, Gassmann M, Thömmes P, Ferrari E, Hafkemeyer P, Hübscher U	1991
Specificity of DNA lesion bypass by the yeast DNA polymerase eta.	Yuan F, Zhang Y, Rajpal DK, Wu X, Guo D, Wang M, Taylor JS, Wang Z	2000
Catalytic subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, bacterial overexpression, and biochemical characterization.	Lewis DL, Farr CL, Wang Y, Lagina AT, Kaguni LS	1996
Replication of the simian virus 40 chromosome with purified proteins.	Ishimi Y, Sugasawa K, Hanaoka F, Kikuchi A	1991
Human DNA polymerase epsilon colocalizes with proliferating cell nuclear antigen and DNA replication late, but not early, in S phase.	Fuss J, Linn S	2002
Studies of deoxyribonucleic acid biosynthesis in embryonic tissues with thymidine-C14.	FRIEDKIN M, TILSON D, ROBERTS D	1956
Enzymatic synthesis of deoxyribonucleic acid. VII. Synthesis of a polymer of deoxyadenylate and deoxythymidylate.	SCHACHMAN HK, Adler J, RADDING CM, Lehman IR, Kornberg A	1960
Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli.	Xu Y, Grindley ND, Joyce CM	2000
Monoclonal antibodies specific for the alpha subunit of the Escherichia coli DNA polymerase III holoenzyme.	Wu YH, Franden MA, Hawker JR, McHenry CS	1984
Translesion synthesis of abasic sites by yeast DNA polymerase epsilon.	Sabouri N, Johansson E	2009
Reduced stimulation of recombinant Pol {gamma} and mtDNA helicase by variants of mitochondrial single-stranded DNA-binding protein (mtSSB) correlates with defects in mtDNA Replication in animal cells.	Oliveira MT, Kaguni LS	2011
Synthesis of DNA by DNA polymerase epsilon in vitro.	Lee SH, Pan ZQ, Kwong AD, Burgers PM, Hurwitz J	1991
Association of DNA primase with the beta/gamma subunits of DNA polymerase alpha from Drosophila melanogaster embryos.	Kaguni LS, Rossignol JM, Conaway RC, Banks GR, Lehman IR	1983
Initiation of DNA replication by simian virus 40 T antigen is inhibited by the p107 protein.	Amin AA, Murakami Y, Hurwitz J	1994
Deoxyribonucleic acid polymerase of bacteriophage T7. Purification and properties of the phage-encoded subunit, the gene 5 protein.	Hori K, Mark DF, Richardson CC	1979
Enzymatic synthesis of deoxyribonucleic acid. 36. A proofreading function for the 3' leads to 5' exonuclease activity in deoxyribonucleic acid polymerases.	Brutlag D, Kornberg A	1972
Nuclear DNA polymerases and the HeLa cell cycle.	Chiu RW, Baril EF	1975
Mode analysis of a fatty acid molecule binding to the N-terminal 8-kDa domain of DNA polymerase beta. A 1:1 complex and binding surface.	Mizushina Y, Ohkubo T, Date T, Yamaguchi T, Saneyoshi M, Sugawara F, Sakaguchi K	1999
Role of a GAG hinge in the nucleotide-induced conformational change governing nucleotide specificity by T7 DNA polymerase.	Jin Z, Johnson KA	2011
The interaction of DNA polymerase III and the product of the Escherichia coli mutator gene, mutD.	DiFrancesco R, Bhatnagar SK, Brown A, Bessman MJ	1984
Kinetic interaction of human immunodeficiency virus type 1 reverse transcriptase with the antiviral tetrahydroimidazo[4,5,1-jk]-[1,4]-benzodiazepine-2-(1H)-thione compound, R82150.	Frank KB, Noll GJ, Connell EV, Sim IS	1991
Kinetic analysis of Escherichia coli deoxyribonucleic acid polymerase I.	Travaglini EC, Mildvan AS, Loeb LA	1975
Purification of a DNA primase activity from the yeast Saccharomyces cerevisiae. Primase can be separated from DNA polymerase I.	Wilson FE, Sugino A	1985
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.	Ohashi E, Bebenek K, Matsuda T, Feaver WJ, Gerlach VL, Friedberg EC, Ohmori H, Kunkel TA	2000
Drosophila DNA polymerase zeta interacts with recombination repair protein 1, the Drosophila homologue of human abasic endonuclease 1.	Takeuchi R, Ruike T, Nakamura R, Shimanouchi K, Kanai Y, Abe Y, Ihara A, Sakaguchi K	2006
DNA damage control by novel DNA polymerases: translesion replication and mutagenesis.	Livneh Z	2001
The Y181C substitution in 3'-azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.	Selmi B, Deval J, Alvarez K, Boretto J, Sarfati S, Guerreiro C, Canard B	2003
Yeast Rev1 protein is a G template-specific DNA polymerase.	Haracska L, Prakash S, Prakash L	2002
Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5'-triphosphate and 3'-azido-3'-deoxythymidine 5'-triphosphate.	Reardon JE, Miller WH	1990
Localization of the active site of HIV-1 reverse transcriptase-associated RNase H domain on a DNA template using site-specific generated hydroxyl radicals.	Götte M, Maier G, Gross HJ, Heumann H	1998
A loss of viral replicative capacity correlates with altered DNA polymerization kinetics by the human immunodeficiency virus reverse transcriptase bearing the K65R and L74V dideoxynucleoside resistance substitutions.	Deval J, Navarro JM, Selmi B, Courcambeck J, Boretto J, Halfon P, Garrido-Urbani S, Sire J, Canard B	2004
Mutational analysis of Tyr-501 of HIV-1 reverse transcriptase. Effects on ribonuclease H activity and inhibition of this activity by N-acylhydrazones.	Arion D, Sluis-Cremer N, Min KL, Abram ME, Fletcher RS, Parniak MA	2002
Discovery of DNA polymerase.	Lehman IR	2003
Real-time kinetics of the interaction between the two subunits, Escherichia coli thioredoxin and gene 5 protein of phage T7 DNA polymerase.	Singha NC, Vlamis-Gardikas A, Holmgren A	2003
An antimutator deoxyribonucleic acid polymerase. I. Purification and properties of the enzyme.	Lo KY, Bessman MJ	1976
Characterization of herpes simplex virus-induced deoxyribonucleic acid polymerase.	Weissbach A, Hong SC, Aucker J, Muller R	1973
Mechanism of T5-induced DNA polymerase. I. Replication of short primer templates.	Das SK, Fujimura RK	1977
Temporal coordination between initiation of HIV (+)-strand DNA synthesis and primer removal.	Götte M, Maier G, Onori AM, Cellai L, Wainberg MA, Heumann H	1999
Kinetic mechanism of the DNA-dependent DNA polymerase activity of human immunodeficiency virus reverse transcriptase.	Hsieh JC, Zinnen S, Modrich P	1993
Species specificity of simian virus 40 DNA replication in vitro requires multiple functions of human DNA polymerase alpha.	Smith RW, Steffen C, Grosse F, Nasheuer HP	2002
Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene.	Gerlach VL, Feaver WJ, Fischhaber PL, Friedberg EC	2001
Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.	Bebenek A, Dressman HK, Carver GT, Ng S, Petrov VM, Yang G, Konigsberg WH, Karam JD, Drake JW	2001
O-helix mutant T664P of Thermus aquaticus DNA polymerase I: altered catalytic properties for incorporation of incorrect nucleotides but not correct nucleotides.	Tosaka A, Ogawa M, Yoshida S, Suzuki M	2001
The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit.	Longley MJ, Nguyen D, Kunkel TA, Copeland WC	2001
Mediation of proliferating cell nuclear antigen (PCNA)-dependent DNA replication through a conserved p21(Cip1)-like PCNA-binding motif present in the third subunit of human DNA polymerase delta.	Ducoux M, Urbach S, Baldacci G, Hübscher U, Koundrioukoff S, Christensen J, Hughes P	2001
Fidelity of DNA polymerases isolated from regenerating liver chromatin of aging Mus musculus.	Silber JR, Fry M, Martin GM, Loeb LA	1985
A model for Escherichia coli DNA polymerase III holoenzyme assembly at primer/template ends. DNA triggers a change in binding specificity of the gamma complex clamp loader.	Ason B, Bertram JG, Hingorani MM, Beechem JM, O'Donnell ME, Goodman MF, Bloom LB	2000
Photoaffinity labeling of DNA template-primer binding site in Escherichia coli DNA polymerase I. Identification of involved amino acids.	Pandey VN, Kaushik N, Modak MJ	1994
The putative coiled coil domain of the phi 29 terminal protein is a major determinant involved in recognition of the origin of replication.	Serna-Rico A, Illana B, Salas M, Meijer WJ	2000
Ferrate oxidation of Escherichia coli DNA polymerase-I. Identification of a methionine residue that is essential for DNA binding.	Basu A, Williams KR, Modak MJ	1987
The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity.	Harrigan JA, Opresko PL, von Kobbe C, Kedar PS, Prasad R, Wilson SH, Bohr VA	2003
Replication bypass of interstrand cross-link intermediates by Escherichia coli DNA polymerase IV.	Kumari A, Minko IG, Harbut MB, Finkel SE, Goodman MF, Lloyd RS	2008
5-Phosphoribosyl 1-pyrophosphate synthetase converts the acyclic nucleoside phosphonates 9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 9-(2-phosphonylmethoxyethyl)adenine directly to their antivirally active diphosphate derivatives.	Balzarini J, De Clercq E	1991
The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation.	Kunkel TA, Alexander PS	1986
Structural and enzymatic studies of the T4 DNA replication system. II. ATPase properties of the polymerase accessory protein complex.	Jarvis TC, Paul LS, Hockensmith JW, von Hippel PH	1989
Gap-filling DNA synthesis by HeLa DNA polymerase alpha in an in vitro base excision DNA repair scheme.	Mosbaugh DW, Linn S	1984
Analysis of a T4 DNA replication protein complex. Studies of the DNA recognition site for T4 gene 44/62 and 45 protein-catalyzed ATP hydrolysis.	Piperno JR, Kallen RG, Alberta BM	1978
Tight association of DNA primase with a subspecies of mouse DNA polymerase alpha.	Yagura T, Tanaka S, Kozu T, Seno T, Korn D	1983
The discovery of RNA polymerase.	Hurwitz J	2005
Immunological relationships between chick embryo polymerases.	Brun GM, Assairi LM, Chapeville F	1975
Photoaffinity labeling of the Klenow fragment with 8-azido-dATP.	Rush J, Konigsberg WH	1990
Purification of gene 41 protein of bacteriophage T4.	Morris CF, Moran LA, Alberts BM	1979
Biochemical characterization of interactions between DNA polymerase and single-stranded DNA-binding protein in bacteriophage RB69.	Sun S, Shamoo Y	2003
Lesion bypass of N2-ethylguanine by human DNA polymerase iota.	Pence MG, Blans P, Zink CN, Hollis T, Fishbein JC, Perrino FW	2009
The bacteriophage phi 29 DNA polymerase, a proofreading enzyme.	Garmendia C, Bernad A, Esteban JA, Blanco L, Salas M	1992
Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase.	Lechner RL, Engler MJ, Richardson CC	1983
Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an alpha-helix in the thumb subdomain.	Beard WA, Stahl SJ, Kim HR, Bebenek K, Kumar A, Strub MP, Becerra SP, Kunkel TA, Wilson SH	1994
Studies on the biochemical basis of spontaneous mutation. I. A comparison of the deoxyribonucleic acid polymerases of mutator, antimutator, and wild type strains of bacteriophage T4.	Muzyczka N, Poland RL, Bessman MJ	1972
Sloppy bypass of an abasic lesion catalyzed by a Y-family DNA polymerase.	Fiala KA, Suo Z	2007
Characterization and mapping of the pyrophosphorolytic activity of the phage phi 29 DNA polymerase. Involvement of amino acid motifs highly conserved in alpha-like DNA polymerases.	Blasco MA, Bernad A, Blanco L, Salas M	1991
Characterization of a large form of DNA polymerase delta from HeLa cells that is insensitive to proliferating cell nuclear antigen.	Syvaoja J, Linn S	1989
Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis.	Stith CM, Sterling JF, Resnick MA, Gordenin DA, Burgers PM	2008
Polymerase dynamics at the eukaryotic DNA replication fork.	Burgers PM	2009
Influence of neighboring bases on DNA polymerase insertion and proofreading fidelity.	Petruska J, Goodman MF	1985
trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases.	Rechkoblit O, Zhang Y, Guo D, Wang Z, Amin S, Krzeminsky J, Louneva N, Geacintov NE	2002
Inefficient bypass of an abasic site by DNA polymerase eta.	Haracska L, Washington MT, Prakash S, Prakash L	2001
Interactions of Escherichia coli thioredoxin, the processivity factor, with bacteriophage T7 DNA polymerase and helicase.	Ghosh S, Hamdan SM, Cook TE, Richardson CC	2008
Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase.	Eckert KA, Kunkel TA	1993
Alterations in the phosphorylation and activity of DNA polymerase alpha correlate with the change in replicative DNA synthesis as quiescent cells re-enter the cell cycle.	Cripps-Wolfman J, Henshaw EC, Bambara RA	1989
Saccharomyces cerevisiae replication factor C. II. Formation and activity of complexes with the proliferating cell nuclear antigen and with DNA polymerases delta and epsilon.	Burgers PM	1991
On the fidelity of DNA replication. Specificity of nucleotide substitution by intercalating agents.	Shearman CW, Loeb LA	1983
An ATP stimulation of T4 DNA polymerase mediated via T4 gene 44/62 and 45 proteins. The requirement for ATP hydrolysis.	Piperno JR, Alberts BM	1978
DNA polymerase beta substrate specificity: side chain modulation of the "A-rule".	Beard WA, Shock DD, Batra VK, Pedersen LC, Wilson SH	2009
Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase eta.	Washington MT, Johnson RE, Prakash S, Prakash L	1999
Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen.	Li X, Li J, Harrington J, Lieber MR, Burgers PM	1995
Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts.	Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP	2009
Interaction of mutant thioredoxins of Escherichia coli with the gene 5 protein of phage T7. The redox capacity of thioredoxin is not required for stimulation of DNA polymerase activity.	Huber HE, Russel M, Model P, Richardson CC	1986
Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7.	Tabor S, Huber HE, Richardson CC	1987
A simple and rapid purification method for Escherichia coli DNA polymerase I.	Rhodes G, Jentsch KD, Jovin TM	1979
Structure of DNA polymerase delta from Saccharomyces cerevisiae.	Johansson E, Majka J, Burgers PM	2001
Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli.	Polesky AH, Dahlberg ME, Benkovic SJ, Grindley ND, Joyce CM	1992
In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells.	Spelbrink JN, Toivonen JM, Hakkaart GA, Kurkela JM, Cooper HM, Lehtinen SK, Lecrenier N, Back JW, Speijer D, Foury F, Jacobs HT	2000
Low fidelity mutants in the O-helix of Thermus aquaticus DNA polymerase I.	Suzuki M, Avicola AK, Hood L, Loeb LA	1997
Baculovirus expression reconstitutes Drosophila mitochondrial DNA polymerase.	Wang Y, Kaguni LS	1999
A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta.	Zhang S, Zhou Y, Trusa S, Meng X, Lee EY, Lee MY	2007
Enzymatic synthesis of deoxyribonucleic acid. XIII. Kinetics of primed and de novo synthesis of deoxynucleotide polymers.	RADDING CM, Kornberg A	1962
Base miscoding and strand misalignment errors by mutator Klenow polymerases with amino acid substitutions at tyrosine 766 in the O helix of the fingers subdomain.	Bell JB, Eckert KA, Joyce CM, Kunkel TA	1997
Fidelity studies of the human DNA polymerase alpha. The most conserved region among alpha-like DNA polymerases is responsible for metal-induced infidelity in DNA synthesis.	Copeland WC, Lam NK, Wang TS	1993
Structural basis for novel interactions between human translesion synthesis polymerases and proliferating cell nuclear antigen.	Hishiki A, Hashimoto H, Hanafusa T, Kamei K, Ohashi E, Shimizu T, Ohmori H, Sato M	2009
Oxygen free radical damage to DNA. Translesion synthesis by human DNA polymerase eta and resistance to exonuclease action at cyclopurine deoxynucleoside residues.	Kuraoka I, Robins P, Masutani C, Hanaoka F, Gasparutto D, Cadet J, Wood RD, Lindahl T	2001
A rapid procedure for isolation of large quantities of Escherichia coli DNA polymerase I utilizing a lambdapolA transducing phage.	Kelley WS, Stump KH	1979
Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus.	Fukuda H, Takamura-Enya T, Masuda Y, Nohmi T, Seki C, Kamiya K, Sugimura T, Masutani C, Hanaoka F, Nakagama H	2009
Interaction of Drosophila DNA polymerase alpha holoenzyme with synthetic template-primers containing mismatched primer bases or propanodeoxyguanosine adducts at various positions in template and primer regions.	Weiss SJ, Fisher PA	1992
Excision of C-4'-oxidized deoxyribose lesions from double-stranded DNA by human apurinic/apyrimidinic endonuclease (Ape1 protein) and DNA polymerase beta.	Xu YJ, Kim EY, Demple B	1998
Chick embryo DNA polymerase alpha. Polypeptide components and their microheterogeneity.	Yamaguchi M, Tanabe K, Takahashi T, Matsukage A	1982
Functional interaction between the herpes simplex-1 DNA polymerase and UL42 protein.	Hernandez TR, Lehman IR	1990
Structural analyses of gp45 sliding clamp interactions during assembly of the bacteriophage T4 DNA polymerase holoenzyme. III. The Gp43 DNA polymerase binds to the same face of the sliding clamp as the clamp loader.	Latham GJ, Bacheller DJ, Pietroni P, von Hippel PH	1997
Herpes simplex virus type 1 DNA polymerase. Mutational analysis of the 3'-5'-exonuclease domain.	Kühn FJ, Knopf CW	1996
DnaX complex of Escherichia coli DNA polymerase III holoenzyme. Physical characterization of the DnaX subunits and complexes.	Dallmann HG, McHenry CS	1995
Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase.	Hsu GW, Kiefer JR, Burnouf DY, Becherel OJ, Fuchs RP, Beese LS	2004
Catalytic subunit of human DNA polymerase alpha overproduced from baculovirus-infected insect cells. Structural and enzymological characterization.	Copeland WC, Wang TS	1991
C-terminal phenylalanine of bacteriophage T7 single-stranded DNA-binding protein is essential for strand displacement synthesis by T7 DNA polymerase at a nick in DNA.	Ghosh S, Marintcheva B, Takahashi M, Richardson CC	2009
The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I.	Bebenek K, Joyce CM, Fitzgerald MP, Kunkel TA	1990
The interaction between DNA polymerase lambda and anticancer nucleoside analogs.	Garcia-Diaz M, Murray MS, Kunkel TA, Chou KM	2010
Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links.	Minko IG, Harbut MB, Kozekov ID, Kozekova A, Jakobs PM, Olson SB, Moses RE, Harris TM, Rizzo CJ, Lloyd RS	2008
Exploring the effects of active site constraints on HIV-1 reverse transcriptase DNA polymerase fidelity.	Cramer J, Strerath M, Marx A, Restle T	2002
In vivo mutagenesis by Escherichia coli DNA polymerase I. Ile(709) in motif A functions in base selection.	Shinkai A, Loeb LA	2001
Characterization of the action of Escherichia coli DNA polymerase I at incisions produced by repair endodeoxyribonucleases.	Mosbaugh DW, Linn S	1982
A study of the mechanism of DNA polymerase I from Escherichia coli with diastereomeric phosphorothioate analogs of deoxyadenosine triphosphate.	Burgers PM, Eckstein F	1979
Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase. Implications for polymerase translocation and drug resistance.	Marchand B, Götte M	2003
Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms.	Ehteshami M, Beilhartz GL, Scarth BJ, Tchesnokov EP, McCormick S, Wynhoven B, Harrigan PR, Götte M	2008
Mutations M184V and Y115F in HIV-1 reverse transcriptase discriminate against "nucleotide-competing reverse transcriptase inhibitors".	Ehteshami M, Scarth BJ, Tchesnokov EP, Dash C, Le Grice SF, Hallenberger S, Jochmans D, Götte M	2008
Contributions of nucleotide excision repair, DNA polymerase eta, and homologous recombination to replication of UV-irradiated herpes simplex virus type 1.	Muylaert I, Elias P	2010
Active site mutations in mammalian DNA polymerase delta alter accuracy and replication fork progression.	Schmitt MW, Venkatesan RN, Pillaire MJ, Hoffmann JS, Sidorova JM, Loeb LA	2010
Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance.	Das K, Bandwar RP, White KL, Feng JY, Sarafianos SG, Tuske S, Tu X, Clark AD, Boyer PL, Hou X, Gaffney BL, Jones RA, Miller MD, Hughes SH, Arnold E	2009
Requirement of DNA polymerase activity of yeast Rad30 protein for its biological function.	Johnson RE, Prakash S, Prakash L	1999
Association of diadenosine 5',5"'-P1,P4-tetraphosphate binding protein with HeLa cell DNA polymerase alpha.	Rapaport E, Zamecnik PC, Baril EF	1981
Serological analysis of human deoxyribonucleic acid polymerases. Preparation and properties of antiserum to deoxyribonucleic acid polymerase I from human lymphoid cells.	Smith RG, Abrell JW, Lewis BJ, Gallo RC	1975
A dynamic polymerase exchange with Escherichia coli DNA polymerase IV replacing DNA polymerase III on the sliding clamp.	Furukohri A, Goodman MF, Maki H	2008
Synthetic template specificity of a deoxyribonucleic acid polymerase from regenerating rat liver.	de Recondo AM, Lepesant JA, Fichot O, Grasset L, Rossignol JM, Cazillis M	1973
Escherichia coli thioredoxin stabilizes complexes of bacteriophage T7 DNA polymerase and primed templates.	Huber HE, Tabor S, Richardson CC	1987
Vaccinia virus uracil DNA glycosylase interacts with the A20 protein to form a heterodimeric processivity factor for the viral DNA polymerase.	Stanitsa ES, Arps L, Traktman P	2006
The dissimilitude of the low and high molecular weight deoxyribonucleic acid-dependent deoxyribonucleic acid polymerases of HeLa cells.	Spadari S, Muller R, Weissbach A	1974
Human DNA polymerase lambda functionally and physically interacts with proliferating cell nuclear antigen in normal and translesion DNA synthesis.	Maga G, Villani G, Ramadan K, Shevelev IV, Tanguy Le Gac N, Blanco L, Blanca G, Spadari S, Hübscher U	2002
Two modes of interaction of the single-stranded DNA-binding protein of bacteriophage T7 with the DNA polymerase-thioredoxin complex.	Ghosh S, Hamdan SM, Richardson CC	2010
Gene 4 protein of bacteriophage T7. Purification physical properties, and stimulation of T7 DNA polymerase during the elongation of polynucleotide chains.	Kolodner R, Masamune Y, LeClerc JE, Richardson CC	1978
Escherichia coli DNA polymerase I. Construction of a polA plasmid for amplification and an improved purification scheme.	Minkley EG, Leney AT, Bodner JB, Panicker MM, Brown WE	1984
Protein-protein interactions between adenovirus DNA polymerase and nuclear factor I mediate formation of the DNA replication preinitiation complex.	Chen M, Mermod N, Horwitz MS	1990
A novel single-stranded DNA-binding protein from the Novikoff hepatoma which stimulates DNA polymerase beta. Purification and general characterization.	Koerner TJ, Meyer RR	1983
Studies on the mechanism of Escherichia coli DNA polymerase I large fragment. Chain termination and modulation by polynucleotides.	Detera SD, Wilson SH	1982
Genetic and biochemical studies of bacteriophage T4 DNA polymerase 3'-->5'-exonuclease activity.	Reha-Krantz LJ, Nonay RL	1993
Mechanism of primer-template-dependent conversion of dNTP leads to dNMP by T5 DNA polymerase.	Das SK, Fujimura RK	1980
Chick embryo DNA polymerase gamma. Purification and structural analysis of nearly homogeneous enzyme.	Yamaguchi M, Matsukage A, Takahashi T	1980
Oxygen-dependent cleavage of DNA by the 1,10-phenanthroline . cuprous complex. Inhibition of Escherichia coli DNA polymerase I.	Sigman DS, Graham DR, D'Aurora V, Stern AM	1979
Enzymological characterization of KB cell DNA polymerase-alpha. II. Specificity of the protein-nucleic acid interaction.	Fisher PA, Korn D	1979
A high molecular weight DNA polymerase from Drosophila melanogaster embryos. Purification, structure, and partial characterization.	Banks GR, Boezi JA, Lehman IR	1979
DNA polymerase III of Escherichia coli. Purification and identification of subunits.	McHenry CS, Crow W	1979
Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1.	Hara K, Hashimoto H, Murakumo Y, Kobayashi S, Kogame T, Unzai S, Akashi S, Takeda S, Shimizu T, Sato M	2010
Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon.	Pascucci B, Stucki M, Jónsson ZO, Dogliotti E, Hübscher U	1999
Characterization of the Bacillus subtilis bacteriophage PBS2-induced DNA polymerase and its associated exonuclease activity.	Hitzeman RA, Price AR	1978
POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308.	Marini F, Kim N, Schuffert A, Wood RD	2003
Human immunodeficiency virus type-1 reverse transcriptase. Contribution of Met-184 to binding of nucleoside 5'-triphosphate.	Wilson JE, Aulabaugh A, Caligan B, McPherson S, Wakefield JK, Jablonski S, Morrow CD, Reardon JE, Furman PA	1996
Purification and characterization of a deoxyribonucleic acid polymerase from rat liver.	Berger H, Huang RC, Irvin JL	1971
The quaternary structure of DNA polymerase epsilon from Saccharomyces cerevisiae.	Chilkova O, Jonsson BH, Johansson E	2003
Nucleotide sequence of the Escherichia coli polA gene and primary structure of DNA polymerase I.	Joyce CM, Kelley WS, Grindley ND	1982
Studies of the DNA helicase-RNA primase unit from bacteriophage T4. A trinucleotide sequence on the DNA template starts RNA primer synthesis.	Cha TA, Alberts BM	1986
In vivo reconstitution of Saccharomyces cerevisiae DNA polymerase epsilon in insect cells. Purification and characterization.	Dua R, Levy DL, Li CM, Snow PM, Campbell JL	2002
The delta and delta ' subunits of the DNA polymerase III holoenzyme are essential for initiation complex formation and processive elongation.	Song MS, Pham PT, Olson M, Carter JR, Franden MA, Schaaper RM, McHenry CS	2001
Fidelity of nucleotide insertion at 8-oxo-7,8-dihydroguanine by mammalian DNA polymerase delta. Steady-state and pre-steady-state kinetic analysis.	Einolf HJ, Guengerich FP	2001
Subunit interactions within the Saccharomyces cerevisiae DNA polymerase epsilon (pol epsilon ) complex. Demonstration of a dimeric pol epsilon.	Dua R, Edwards S, Levy DL, Campbell JL	2000
Mechanism of beta clamp opening by the delta subunit of Escherichia coli DNA polymerase III holoenzyme.	Stewart J, Hingorani MM, Kelman Z, O'Donnell ME	2001
Distinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions.	Bermek O, Grindley ND, Joyce CM	2011
Replication factor C disengages from proliferating cell nuclear antigen (PCNA) upon sliding clamp formation, and PCNA itself tethers DNA polymerase delta to DNA.	Podust VN, Tiwari N, Stephan S, Fanning E	1998
Human DNA polymerase beta recognizes single-stranded DNA using two different binding modes.	Rajendran S, Jezewska MJ, Bujalowski W	1998
Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme.	Hamatake RK, Hasegawa H, Clark AB, Bebenek K, Kunkel TA, Sugino A	1990
Thermodynamics of human DNA ligase I trimerization and association with DNA polymerase beta.	Dimitriadis EK, Prasad R, Vaske MK, Chen L, Tomkinson AE, Lewis MS, Wilson SH	1998
The acidic carboxyl terminus of the bacteriophage T7 gene 4 helicase/primase interacts with T7 DNA polymerase.	Notarnicola SM, Mulcahy HL, Lee J, Richardson CC	1997
Interaction of DNA polymerase delta, proliferating cell nuclear antigen, and synthetic oligonucleotide template-primers. Analysis by polyacrylamide gel electrophoresis-band mobility shift assay.	Ng L, McConnell M, Tan CK, Downey KM, Fisher PA	1993
The identification of prereplicative bacteriophage T4 proteins.	O'Farrell PZ, Gold L, Huang WM	1973
Bacteriophage T7 Deoxyribonucleic acid replication in vitro. A protein of Escherichia coli required for bacteriophage T7 DNA polymerase activity.	Modrich P, Richardson CC	1975
Processivity of mitochondrial DNA polymerase from Drosophila embryos. Effects of reaction conditions and enzyme purity.	Williams AJ, Wernette CM, Kaguni LS	1993
DNA polymerase alpha stimulates the ATP-dependent binding of simian virus tumor T antigen to the SV40 origin of replication.	Murakami Y, Hurwitz J	1993
Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. IV. Reconstitution of an asymmetric, dimeric DNA polymerase III holoenzyme.	Wu CA, Zechner EL, Hughes AJ, Franden MA, McHenry CS, Marians KJ	1992
Analysis of the ATPase subassembly which initiates processive DNA synthesis by DNA polymerase III holoenzyme.	Onrust R, Stukenberg PT, O'Donnell ME	1991
DNA polymerase insertion fidelity. Gel assay for site-specific kinetics.	Boosalis MS, Petruska J, Goodman MF	1987
Murine DNA polymerase alpha fills gaps to completion in a direct assay. Altered kinetics of de novo DNA synthesis at single nucleotide gaps.	Davey SK, Faust EA	1990
Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase.	Tchesnokov EP, Obikhod A, Massud I, Lisco A, Vanpouille C, Brichacek B, Balzarini J, McGuigan C, Derudas M, Margolis L, Schinazi RF, Götte M	2009
Using 2-aminopurine fluorescence and mutational analysis to demonstrate an active role of bacteriophage T4 DNA polymerase in strand separation required for 3' --> 5'-exonuclease activity.	Marquez LA, Reha-Krantz LJ	1996
Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates.	Ueno T, Shirasaka T, Mitsuya H	1995
Residues in the alphaH and alphaI helices of the HIV-1 reverse transcriptase thumb subdomain required for the specificity of RNase H-catalyzed removal of the polypurine tract primer.	Powell MD, Beard WA, Bebenek K, Howard KJ, Le Grice SF, Darden TA, Kunkel TA, Wilson SH, Levin JG	1999
DNA end joining by the Klenow fragment of DNA polymerase I.	King JS, Fairley CF, Morgan WF	1996
The mutational specificity of the Dbh lesion bypass polymerase and its implications.	Potapova O, Grindley ND, Joyce CM	2002
Importance of hydrogen bonding for efficiency and specificity of the human mitochondrial DNA polymerase.	Lee HR, Helquist SA, Kool ET, Johnson KA	2008
Low molecular weight deoxyribonucleic acid polymerase in mammalian cells.	Chang LM, Bollum FJ	1971
Identification of a fourth subunit of mammalian DNA polymerase delta.	Liu L, Mo J, Rodriguez-Belmonte EM, Lee MY	2000
The Gly-952 residue of Saccharomyces cerevisiae DNA polymerase alpha is important in discriminating correct deoxyribonucleotides from incorrect ones.	Limsirichaikul S, Ogawa M, Niimi A, Iwai S, Murate T, Yoshida S, Suzuki M	2003
Identification of 100 and 150 S DNA polymerase alpha-primase megacomplexes solubilized from the nuclear matrix of regenerating rat liver.	Tubo RA, Berezney R	1987
Chemical characterization and purification of the beta subunit of the DNA polymerase III holoenzyme from an overproducing strain.	Johanson KO, Haynes TE, McHenry CS	1986
Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase delta.	Venkatesan RN, Hsu JJ, Lawrence NA, Preston BD, Loeb LA	2006
Investigation of stoichiometry of T4 bacteriophage helicase loader protein (gp59).	Arumugam SR, Lee TH, Benkovic SJ	2009
Structural and functional elucidation of the mechanism promoting error-prone synthesis by human DNA polymerase kappa opposite the 7,8-dihydro-8-oxo-2'-deoxyguanosine adduct.	Irimia A, Eoff RL, Guengerich FP, Egli M	2009
phi 29 DNA polymerase residue Leu384, highly conserved in motif B of eukaryotic type DNA replicases, is involved in nucleotide insertion fidelity.	Truniger V, Lázaro JM, de Vega M, Blanco L, Salas M	2003
DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. Effect of pyrophosphorolysis and metal ions.	Tabor S, Richardson CC	1990
The carboxyl terminus of the bacteriophage T4 DNA polymerase contacts its sliding clamp at the subunit interface.	Alley SC, Jones AD, Soumillion P, Benkovic SJ	1999
Strand displacement by DNA polymerase III occurs through a tau-psi-chi link to single-stranded DNA-binding protein coating the lagging strand template.	Yuan Q, McHenry CS	2009
Conformational changes during nucleotide selection by Sulfolobus solfataricus DNA polymerase Dpo4.	Eoff RL, Sanchez-Ponce R, Guengerich FP	2009
Increased dNTP binding affinity reveals a nonprocessive role for Escherichia coli beta clamp with DNA polymerase IV.	Bertram JG, Bloom LB, O'Donnell ME, Goodman MF	2004
Enzymological characterization of KB cell DNA polymerase-alpha. III. The polymerization reaction with single-stranded DNA.	Fisher PA, Korn D	1979
Characterization of the ribonucleic acid primers and the deoxyribonucleic acid product synthesized by the DNA polymerase and gene 4 protein of bacteriophage T7.	Romano LJ, Richardson CC	1979
Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, and Ctf8.	Murakami T, Takano R, Takeo S, Taniguchi R, Ogawa K, Ohashi E, Tsurimoto T	2010
Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation.	Zhang H, Beckman JW, Guengerich FP	2009
A DNA polymerase-{alpha}{middle dot}primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells.	Casteel DE, Zhuang S, Zeng Y, Perrino FW, Boss GR, Goulian M, Pilz RB	2009
Only one ATP-binding DnaX subunit is required for initiation complex formation by the Escherichia coli DNA polymerase III holoenzyme.	Wieczorek A, Downey CD, Dallmann HG, McHenry CS	2010
A specific docking site for DNA polymerase {alpha}-primase on the SV40 helicase is required for viral primosome activity, but helicase activity is dispensable.	Huang H, Zhao K, Arnett DR, Fanning E	2010
Human DNA polymerase beta mutations allowing efficient abasic site bypass.	Gieseking S, Bergen K, Di Pasquale F, Diederichs K, Welte W, Marx A	2011
A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase eta activity.	Shiomi Y, Masutani C, Hanaoka F, Kimura H, Tsurimoto T	2007
Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex.	Kirby TW, Harvey S, DeRose EF, Chalov S, Chikova AK, Perrino FW, Schaaper RM, London RE, Pedersen LC	2006
Amino acid sequence motifs essential to 3'-->5' exonuclease activity of Escherichia coli DNA polymerase II.	Ishino Y, Iwasaki H, Kato I, Shinagawa H	1994
Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations.	Deval J, White KL, Miller MD, Parkin NT, Courcambeck J, Halfon P, Selmi B, Boretto J, Canard B	2004
Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities.	Chang DJ, Lupardus PJ, Cimprich KA	2006
Deoxyribonucleic acid polymerase of bacteriophage T7. Characterization of the exonuclease activities of the gene 5 protein and the reconstituted polymerase.	Hori K, Mark DF, Richardson CC	1979
Pre-steady-state kinetic characterization of the DinB homologue DNA polymerase of Sulfolobus solfataricus.	Cramer J, Restle T	2005
Stimulation of Drosophila mitochondrial DNA polymerase by single-stranded DNA-binding protein.	Williams AJ, Kaguni LS	1995
Deoxynucleoside triphosphate and pyrophosphate binding sites in the catalytically competent ternary complex for the polymerase reaction catalyzed by DNA polymerase I (Klenow fragment).	Astatke M, Grindley ND, Joyce CM	1995
Mutations in the spacer region of Drosophila mitochondrial DNA polymerase affect DNA binding, processivity, and the balance between Pol and Exo function.	Luo N, Kaguni LS	2005
Studies of gapped DNA substrate binding by mammalian DNA polymerase beta. Dependence on 5'-phosphate group.	Prasad R, Beard WA, Wilson SH	1994
Herpes simplex-1 DNA polymerase. Identification of an intrinsic 5'----3' exonuclease with ribonuclease H activity.	Crute JJ, Lehman IR	1989
Oxidation of thymine to 5-formyluracil in DNA promotes misincorporation of dGMP and subsequent elongation of a mismatched primer terminus by DNA polymerase.	Masaoka A, Terato H, Kobayashi M, Ohyama Y, Ide H	2001
DNA structure requirements for the Escherichia coli gamma complex clamp loader and DNA polymerase III holoenzyme.	Yao N, Leu FP, Anjelkovic J, Turner J, O'Donnell ME	2000
The delta subunit of DNA polymerase III holoenzyme serves as a sliding clamp unloader in Escherichia coli.	Leu FP, Hingorani MM, Turner J, O'Donnell ME	2000
Dynamics of loading the beta sliding clamp of DNA polymerase III onto DNA.	Bloom LB, Turner J, Kelman Z, Beechem JM, O'Donnell ME, Goodman MF	1996
DNA polymerase III accessory proteins. II. Characterization of delta and delta'.	Onrust R, O'Donnell ME	1993
Point mutations which drastically affect the polymerization activity of encephalomyocarditis virus RNA-dependent RNA polymerase correspond to the active site of Escherichia coli DNA polymerase I.	Sankar S, Porter AG	1992
Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme.	Stukenberg PT, Studwell-Vaughan PS, O'Donnell ME	1991
The infidelity of avian myeloblastosis virus deoxyribonucleic acid polymerase in polynucleotide replication.	Battula N, Loeb LA	1974
DNA polymerase III holoenzyme of Escherichia coli. II. A novel complex including the gamma subunit essential for processive synthesis.	Maki S, Kornberg A	1988
Characterization of the homopolymer tailing reaction catalyzed by terminal deoxynucleotidyl transferase. Implications for the cloning of cDNA.	Michelson AM, Orkin SH	1982
Nuclear location of mammalian DNA polymerase activities.	Foster DN, Gurney T	1976
DNA polymerase beta ribonucleotide discrimination: insertion, misinsertion, extension, and coding.	Cavanaugh NA, Beard WA, Wilson SH	2010
DNA polymerase beta conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract.	Singhal RK, Prasad R, Wilson SH	1995
Sulfolobus solfataricus DNA polymerase Dpo4 is partially inhibited by "wobble" pairing between O6-methylguanine and cytosine, but accurate bypass is preferred.	Eoff RL, Irimia A, Egli M, Guengerich FP	2007
Action of mitochondrial DNA polymerase gamma at sites of base loss or oxidative damage.	Pinz KG, Shibutani S, Bogenhagen DF	1995
Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair.	Oliveros M, Yáñez RJ, Salas ML, Salas J, Viñuela E, Blanco L	1997
Characterization of 2'(3')-trinitrophenyl-ATP as an inhibitor of ATP-dependent initiation complex formation between the DNA polymerase III holoenzyme and primed DNA.	Oberfelder R, McHenry CS	1987
A novel ochre mutation in the beta-thalassemia gene of a Thai. Identification by direct cloning of the entire beta-globin gene amplified using polymerase chain reactions.	Fucharoen S, Fucharoen G, Fucharoen P, Fukumaki Y	1989
The slow dissociation of the T4 DNA polymerase holoenzyme when stalled by nucleotide omission. An indication of a highly processive enzyme.	Hacker KJ, Alberts BM	1994
Dissection of RNA-primed DNA synthesis catalyzed by gene 4 protein and DNA polymerase of bacteriophage T7. Coupling of RNA primer and DNA synthesis.	Nakai H, Richardson CC	1986
DNA polymerase of mitochondria is a gamma-polymerase.	Bolden A, Noy GP, Weissbach A	1977
The adenovirus DNA binding protein and adenovirus DNA polymerase interact to catalyze elongation of primed DNA templates.	Lindenbaum JO, Field J, Hurwitz J	1986
Highly tolerated amino acid substitutions increase the fidelity of Escherichia coli DNA polymerase I.	Loh E, Choe J, Loeb LA	2007
A dynamic RecA filament permits DNA polymerase-catalyzed extension of the invading strand in recombination intermediates.	Xu L, Marians KJ	2002
Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta.	Lu X, Tan CK, Zhou JQ, You M, Carastro LM, Downey KM, So AG	2002
A comparative study of the effect of normal substrates and 5-iodo-2'-deoxyuridine triphosphate, a metabolic analog of thymidine triphosphate, on the inactivation of Escherichia coli deoxyribonucleic acid polymerase I and II by ultraviolet irradiation.	Ku KY, Prusoff WH	1974
Differential extension of 3' mispairs is a major contribution to the high fidelity of calf thymus DNA polymerase-alpha.	Perrino FW, Loeb LA	1989
A single highly mutable catalytic site amino acid is critical for DNA polymerase fidelity.	Patel PH, Kawate H, Adman E, Ashbach M, Loeb LA	2001
Inhibition of herpes simplex virus DNA polymerase by purine ribonucleoside monophosphates.	Frank KB, Cheng YC	1986
To slip or skip, visualizing frameshift mutation dynamics for error-prone DNA polymerases.	Tippin B, Kobayashi S, Bertram JG, Goodman MF	2004
A computer-assisted analysis of conserved residues in the three-dimensional structures of the polymerase domains of Escherichia coli DNA polymerase I and HIV-1 reverse transcriptase.	Yadav PN, Yadav JS, Arnold E, Modak MJ	1994
Initiation of DNA synthesis by the calf thymus DNA polymerase-primase complex.	Holmes AM, Cheriathundam E, Bollum FJ, Chang LM	1985
Processive proofreading is intrinsic to T4 DNA polymerase.	Reddy MK, Weitzel SE, von Hippel PH	1992
Tumor suppressor APC blocks DNA polymerase beta-dependent strand displacement synthesis during long patch but not short patch base excision repair and increases sensitivity to methylmethane sulfonate.	Narayan S, Jaiswal AS, Balusu R	2005
Modulation of the 5'-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1.	Wong D, Demple B	2004
DNA polymerases from bakers' yeast.	Chang LM	1977
Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair.	Raffoul JJ, Cabelof DC, Nakamura J, Meira LB, Friedberg EC, Heydari AR	2004
A DNA primase that copurifies with the major DNA polymerase from the yeast Saccharomyces cerevisiae.	Singh H, Dumas LB	1984
DNA functional groups required for formation of open complexes between Escherichia coli RNA polymerase and the lambda PR promoter. Identification via base analog substitutions.	Dubendorff JW, deHaseth PL, Rosendahl MS, Caruthers MH	1987
Poly(ADP-ribose) polymerase-1 (PARP-1) is required in murine cell lines for base excision repair of oxidative DNA damage in the absence of DNA polymerase beta.	Le Page F, Schreiber V, Dherin C, de Murcia G, Boiteux S	2003
DNA polymerase III from Escherichia coli cells expressing mutA mistranslator tRNA is error-prone.	Al Mamun AA, Marians KJ, Humayun MZ	2002
Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae.	Shimizu K, Hashimoto K, Kirchner JM, Nakai W, Nishikawa H, Resnick MA, Sugino A	2002
Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency.	Canceill D, Viguera E, Ehrlich SD	1999
Base substitution specificity of DNA polymerase beta depends on interactions in the DNA minor groove.	Osheroff WP, Beard WA, Wilson SH, Kunkel TA	1999
Characterization of the DNA-dependent GTPase activity of T4 gene 41 protein, an essential component of the T4 bacteriophage DNA replication apparatus.	Liu CC, Alberts BM	1981
Building a replisome solution structure by elucidation of protein-protein interactions in the bacteriophage T4 DNA polymerase holoenzyme.	Alley SC, Trakselis MA, Mayer MU, Ishmael FT, Jones AD, Benkovic SJ	2001
Enzymatic synthesis of deoxyribonucleic acid. XXX. Binding of triphosphates to deoxyribonucleic acid polymerase.	Englund PT, Huberman JA, Jovin TM, Kornberg A	1969
Enzymatic synthesis of deoxyribonucleic acid. XXIX. Hydrolysis of deoxyribonucleic acid from the 5' terminus by an exonuclease function of deoxyribonucleic acid polymerase.	Deutscher MP, Kornberg A	1969
Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5' leads to 3' exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments.	Setlow P, Kornberg A	1972
Engineering of a chimeric RB69 DNA polymerase sensitive to drugs targeting the cytomegalovirus enzyme.	Tchesnokov EP, Obikhod A, Schinazi RF, Götte M	2009
Gel kinetic analysis of DNA polymerase fidelity in the presence of proofreading using bacteriophage T4 DNA polymerase.	Creighton S, Goodman MF	1995
Structure of the functional domain of phi29 replication organizer: insights into oligomerization and dna binding.	Asensio JL, Albert A, Muñoz-Espín D, Gonzalez C, Hermoso J, Villar L, Jiménez-Barbero J, Salas M, Meijer WJ	2005
Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase alpha.	Ogawa M, Limsirichaikul S, Niimi A, Iwai S, Yoshida S, Suzuki M	2003
Purification of the gene 43, 44, 45, and 62 proteins of the bacteriophage T4 DNA replication apparatus.	Morris CF, Hama-Inaba H, Mace D, Sinha NK, Alberts B	1979
DNA footprinting studies of the complex formed by the T4 DNA polymerase holoenzyme at a primer-template junction.	Munn MM, Alberts BM	1991
DNA polymerase beta involvement in DNA endoreduplication in rat giant trophoblast cells.	Siegel RL, Kalf GF	1982
Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases.	Reha-Krantz LJ, Nonay RL, Day RS, Wilson SH	1996
On the fidelity of DNA replication. Metal activation of Escherichia coli DNA polymerase I.	Sirover MA, Dube DK, Loeb LA	1979
Enzymatic synthesis of deoxyribonucleic acid. 28. The pyrophosphate exchange and pyrophosphorolysis reactions of deoxyribonucleic acid polymerase.	Deutscher MP, Kornberg A	1969
Deoxyribonucleic acid synthesis in cell-free extracts. IV. Purification and catalytic properties of deoxyribonucleic acid polymerase III.	Kornberg T, Gefter ML	1972
Utilization of desoxyribosides in the synthesis of polynucleotides.	REICHARD P, ESTBORN B	1951
Bacteriophage T4 gene 44/62 and gene 45 polymerase accessory proteins stimulate hydrolysis of duplex DNA by T4 DNA polymerase.	Venkatesan M, Nossal NG	1982
Bacteriophage T4 32 protein is required for helicase-dependent leading strand synthesis when the helicase is loaded by the T4 59 helicase-loading protein.	Jones CE, Mueser TC, Nossal NG	2004
Drosophila DNA polymerase delta. Purification and characterization.	Aoyagi N, Matsuoka S, Furunobu A, Matsukage A, Sakaguchi K	1994
Y265H mutator mutant of DNA polymerase beta. Proper teometric alignment is critical for fidelity.	Shah AM, Li SX, Anderson KS, Sweasy JB	2001
The 3'-5' proofreading exonuclease of bacteriophage T4 DNA polymerase is stimulated by other T4 DNA replication proteins.	Bedinger P, Alberts BM	1983
The UvsY protein of bacteriophage T4 modulates recombination-dependent DNA synthesis in vitro.	Morrical SW, Alberts BM	1990
Purification and characterization of the bacteriophage T4 dda protein. A DNA helicase that associates with the viral helix-destabilizing protein.	Jongeneel CV, Formosa T, Alberts BM	1984
Binding specificity of T4 DNA polymerase to RNA.	Pavlov AR, Karam JD	1994
Protein determinants of RNA binding by DNA polymerase of the T4-related bacteriophage RB69.	Petrov VM, Ng SS, Karam JD	2002
Purification and characterization of the 180- and 86-kilodalton subunits of the Saccharomyces cerevisiae DNA primase-DNA polymerase protein complex. The 180-kilodalton subunit has both DNA polymerase and 3'----5'-exonuclease activities.	Brooke RG, Singhal R, Hinkle DC, Dumas LB	1991
Primary structure of T4 DNA polymerase. Evolutionary relatedness to eucaryotic and other procaryotic DNA polymerases.	Spicer EK, Rush J, Fung C, Reha-Krantz LJ, Karam JD, Konigsberg WH	1988
DNA-independent deoxynucleotidylation of the phi 29 terminal protein by the phi 29 DNA polymerase.	Blanco L, Bernad A, Esteban JA, Salas M	1992
Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family.	Hogg M, Aller P, Konigsberg WH, Wallace SS, Doublié S	2007
Phi 29 DNA polymerase active site. The conserved amino acid motif "Kx3NSxYG" is involved in template-primer binding and dNTP selection.	Blasco MA, Lázaro JM, Blanco L, Salas M	1993
Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II.	Selby CP, Sancar A	1997
Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase.	Sherrer SM, Brown JA, Pack LR, Jasti VP, Fowler JD, Basu AK, Suo Z	2009
Kinetic effect of a downstream strand and its 5'-terminal moieties on single nucleotide gap-filling synthesis catalyzed by human DNA polymerase lambda.	Duym WW, Fiala KA, Bhatt N, Suo Z	2006
DNA polymerase V allows bypass of toxic guanine oxidation products in vivo.	Neeley WL, Delaney S, Alekseyev YO, Jarosz DF, Delaney JC, Walker GC, Essigmann JM	2007
The family X DNA polymerase from Deinococcus radiodurans adopts a non-standard extended conformation.	Leulliot N, Cladière L, Lecointe F, Durand D, Hübscher U, van Tilbeurgh H	2009
The DNA sequence specificity of stimulation of DNA polymerases by factor D.	Fry M, Sharf R, Weisman-Shomer P, Evers PC, Loeb LA	1987
A study of the mechanism of T4 DNA polymerase with diastereomeric phosphorothioate analogues of deoxyadenosine triphosphate.	Romaniuk PJ, Eckstein F	1982
Error-prone translesion synthesis by human DNA polymerase eta on DNA-containing deoxyadenosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.	Chiapperino D, Cai M, Sayer JM, Yagi H, Kroth H, Masutani C, Hanaoka F, Jerina DM, Cheh AM	2005
Evidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reaction.	Piersen CE, Prasad R, Wilson SH, Lloyd RS	1996
Preparation of DNA polymerase alpha X C1C2 by reconstituting DNA polymerase alpha with its specific stimulatory cofactors, C1C2.	Pritchard CG, DePamphilis ML	1983
The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches.	Perlow-Poehnelt RA, Likhterov I, Scicchitano DA, Geacintov NE, Broyde S	2004
Products of DNA cleavage by the 1,10-phenanthroline-copper complex. Inhibitors of Escherichia coli DNA polymerase I.	Pope LM, Reich KA, Graham DR, Sigman DS	1982
DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A.	Maga G, Ramadan K, Locatelli GA, Shevelev IV, Spadari S, Hübscher U	2005
Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli.	Fay PJ, Johanson KO, McHenry CS, Bambara RA	1981
Excess beta subunit can bypass the ATP requirement for highly processive synthesis by the Escherichia coli DNA polymerase III holoenzyme.	Crute JJ, LaDuca RJ, Johanson KO, McHenry CS, Bambara RA	1983
Phi 29 DNA polymerase active site. Residue ASP249 of conserved amino acid motif "Dx2SLYP" is critical for synthetic activities.	Blasco MA, Lázaro JM, Blanco L, Salas M	1993
Mitochondrial DNA replication does not involve DNA polymerase alpha.	Zimmermann W, Chen SM, Bolden A, Weissbach A	1980
Novel interaction of aphidicolin with herpes simplex virus DNA polymerase and polymerase-associated exonuclease.	Frank KB, Derse DD, Bastow KF, Cheng YC	1984
DNA polymerase alpha.	Lehman IR, Kaguni LS	1989
A carboxylate triad is essential for the polymerase activity of Escherichia coli DNA polymerase I (Klenow fragment). Presence of two functional triads at the catalytic center.	Gangurde R, Kaushik N, Singh K, Modak MJ	2000
New human immunodeficiency virus, type 1 reverse transcriptase (HIV-1 RT) mutants with increased fidelity of DNA synthesis. Accuracy, template binding, and processivity.	Kim B, Ayran JC, Sagar SG, Adman ET, Fuller SM, Tran NH, Horrigan J	1999
The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine.	Schuckmann MM, Marchand B, Hachiya A, Kodama EN, Kirby KA, Singh K, Sarafianos SG	2010
Mutations in the primer grip region of HIV reverse transcriptase can increase replication fidelity.	Wisniewski M, Palaniappan C, Fu Z, Le Grice SF, Fay P, Bambara RA	1999
Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment).	Minnick DT, Bebenek K, Osheroff WP, Turner RM, Astatke M, Liu L, Kunkel TA, Joyce CM	1999
Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: II. Uncoupling the beta and DNA binding activities of the gamma complex.	Snyder AK, Williams CR, Johnson A, O'Donnell ME, Bloom LB	2004
Preparation and preliminary characterization of monoclonal antibodies against human DNA polymerase alpha.	Tanaka S, Hu SZ, Wang TS, Korn D	1982
Selective excision of chain-terminating nucleotides by HIV-1 reverse transcriptase with phosphonoformate as substrate.	Cruchaga C, Ansó E, Rouzaut A, Martínez-Irujo JJ	2006
On the molecular basis of transition mutations. Frequency of forming 2-aminopurine-cytosine base mispairs in the G X C----A X T mutational pathway by T4 DNA polymerase in vitro.	Mhaskar DN, Goodman MF	1984
Mutational and pH studies of the 3' --> 5' exonuclease activity of bacteriophage T4 DNA polymerase.	Elisseeva E, Mandal SS, Reha-Krantz LJ	1999
DNA polymerase I of Mycobacterium tuberculosis: functional role of a conserved aspartate in the hinge joining the M and N helices.	Arrigo CJ, Singh K, Modak MJ	2002
The Pol32 subunit of DNA polymerase delta contains separable domains for processive replication and proliferating cell nuclear antigen (PCNA) binding.	Johansson E, Garg P, Burgers PM	2004
Purification and characterization of the catalytic subunit of human DNA polymerase delta expressed in baculovirus-infected insect cells.	Zhou JQ, Tan CK, So AG, Downey KM	1996
Carboxyl-terminal domain III of the delta' subunit of DNA polymerase III holoenzyme binds DnaX and supports cooperative DnaX complex assembly.	Song MS, McHenry CS	2001
Identification of a point mutation in the cDNA of the catalytic subunit of DNA polymerase alpha from a temperature-sensitive mouse FM3A cell line.	Izumi M, Miyazawa H, Harakawa S, Yatagai F, Hanaoka F	1994
Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44.	Appleton BA, Brooks J, Loregian A, Filman DJ, Coen DM, Hogle JM	2006
Double-stranded DNA binding, an unusual property of DNA polymerase epsilon, promotes epigenetic silencing in Saccharomyces cerevisiae.	Tsubota T, Tajima R, Ode K, Kubota H, Fukuhara N, Kawabata T, Maki S, Maki H	2006
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Assembly of DNA polymerase III holoenzyme: co-assembly of gamma and tau is inhibited by DnaX complex accessory proteins but stimulated by DNA polymerase III core.	Pritchard AE, McHenry CS	2001
Bacteriophage T4 DNA primase-helicase. Characterization of the DNA synthesis primed by T4 61 protein in the absence of T4 41 protein.	Nossal NG, Hinton DM	1987
Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication.	Hsu GW, Huang X, Luneva NP, Geacintov NE, Beese LS	2005
Two forms of the DNA polymerase of bacteriophage T7.	Engler MJ, Lechner RL, Richardson CC	1983
Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase.	Johnson AA, Ray AS, Hanes J, Suo Z, Colacino JM, Anderson KS, Johnson KA	2001
Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms.	Clayton LK, Goodman MF, Branscomb EW, Galas DJ	1979
Identification and characterization of human DNA polymerase beta 2, a DNA polymerase beta -related enzyme.	Nagasawa K, Kitamura K, Yasui A, Nimura Y, Ikeda K, Hirai M, Matsukage A, Nakanishi M	2000
Intracellular localization of human DNA polymerase alpha with monoclonal antibodies.	Bensch KG, Tanaka S, Hu SZ, Wang TS, Korn D	1982
Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli.	Polesky AH, Steitz TA, Grindley ND, Joyce CM	1990
Spatial relationship between polymerase and exonuclease active sites of phage T4 DNA polymerase enzyme.	Gopalakrishnan V, Benkovic SJ	1994
Regulation of human DNA polymerase delta during the cell cycle.	Zeng XR, Hao H, Jiang Y, Lee MY	1994
Control of mutation frequency by bacteriophage T4 DNA polymerase. II. Accuracy of nucleotide selection by the L88 mutator, CB120 antimutator, and wild type phage T4 DNA polymerases.	Gillin FD, Nossal NG	1976
Phi 29 DNA polymerase active site. Mutants in conserved residues Tyr254 and Tyr390 are affected in dNTP binding.	Blasco MA, Lázaro JM, Bernad A, Blanco L, Salas M	1992
Molecular cloning of the cDNAs for the four subunits of mouse DNA polymerase alpha-primase complex and their gene expression during cell proliferation and the cell cycle.	Miyazawa H, Izumi M, Tada S, Takada R, Masutani M, Ui M, Hanaoka F	1993
"Action-at-a-distance" mutagenesis. 8-oxo-7, 8-dihydro-2'-deoxyguanosine causes base substitution errors at neighboring template sites when copied by DNA polymerase beta.	Efrati E, Tocco G, Eritja R, Wilson SH, Goodman MF	1999
The conserved active site motif A of Escherichia coli DNA polymerase I is highly mutable.	Shinkai A, Patel PH, Loeb LA	2001
The fidelity of DNA polymerase beta during distributive and processive DNA synthesis.	Osheroff WP, Jung HK, Beard WA, Wilson SH, Kunkel TA	1999
T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups.	Adler S, Modrich P	1983
Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR.	Méndez J, Blanco L, Lázaro JM, Salas M	1994
The chi psi subunits of DNA polymerase III holoenzyme bind to single-stranded DNA-binding protein (SSB) and facilitate replication of an SSB-coated template.	Glover BP, McHenry CS	1998
An error-correcting proofreading exonuclease-polymerase that copurifies with DNA-polymerase-alpha-primase.	Bialek G, Grosse F	1993
Saccharomyces cerevisiae DNA polymerase delta: high fidelity for base substitutions but lower fidelity for single- and multi-base deletions.	Fortune JM, Pavlov YI, Welch CM, Johansson E, Burgers PM, Kunkel TA	2005
Characterization of DNA polymerase I*, a form of DNA polymerase I found in Escherichia coli expressing SOS functions.	Lackey D, Krauss SW, Linn S	1985
Processive replication of single-stranded DNA templates by the herpes simplex virus-induced DNA polymerase.	O'Donnell ME, Elias P, Lehman IR	1987
DNA polymerase delta is involved in the cellular response to UV damage in human cells.	Zeng XR, Jiang Y, Zhang SJ, Hao H, Lee MY	1994
Fidelity of human DNA polymerase eta.	Johnson RE, Washington MT, Prakash S, Prakash L	2000
DNA polymerase delta is required for human mismatch repair in vitro.	Longley MJ, Pierce AJ, Modrich P	1997
Adriamycin interactions with T4 DNA polymerase. Two modes of template-mediated inhibition.	Goodman MF, Lee GM	1977
Template primer-dependent binding of 5'-fluorosulfonyl-benzoyldeoxyadenosine by Escherichia coli DNA polymerase I. Identification of arginine 682 as the binding site and its implication in catalysis.	Pandey VN, Kaushik NA, Pradhan DS, Modak MJ	1990
On the fidelity of DNA replication. Effect of metal activators during synthesis with avian myeloblastosis virus DNA polymerase.	Sirover MA, Loeb LA	1977
Thermus aquaticus DNA polymerase I mutants with altered fidelity. Interacting mutations in the O-helix.	Suzuki M, Yoshida S, Adman ET, Blank A, Loeb LA	2000
Incorporation of cytosine arabinoside monophosphate into DNA at internucleotide linkages by human DNA polymerase alpha.	Perrino FW, Mekosh HL	1992
Acyclovir triphosphate is a suicide inactivator of the herpes simplex virus DNA polymerase.	Furman PA, St Clair MH, Spector T	1984
Role of the bacteriophage T7 and T4 single-stranded DNA-binding proteins in the formation of joint molecules and DNA helicase-catalyzed polar branch migration.	Kong D, Nossal NG, Richardson CC	1997
DNA primase from KB cells. Characterization of a primase activity tightly associated with immunoaffinity-purified DNA polymerase-alpha.	Wang TS, Hu SZ, Korn D	1984
Ribonucleoside and deoxyribonucleoside triphosphate pools during 2-aminopurine mutagenesis in T4 mutator-, wild type-, and antimutator-infected Escherichia coli.	Hopkins RL, Goodman MF	1985
Multiple amino acid substitutions allow DNA polymerases to synthesize RNA.	Patel PH, Loeb LA	2000
On the fidelity of DNA replication. Effect of divalent metal ion activators and deoxyrionucleoside triphosphate pools on in vitro mutagenesis.	Kunkel TA, Loeb LA	1979
On the processive mechanism of Escherichia coli DNA polymerase I. Quantitative assessment of processivity.	Bambara RA, Uyemura D, Choi T	1978
Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene.	Irimia A, Eoff RL, Pallan PS, Guengerich FP, Egli M	2007
The T4 DNA polymerase accessory proteins form an ATP-dependent complex on a primer-template junction.	Munn MM, Alberts BM	1991
The biochemical basis of 5-bromouracil-induced mutagenesis. Heteroduplex base mispairs involving bromouracil in G x C----A x T and A x T----G x C mutational pathways.	Lasken RS, Goodman MF	1984
Escherichia coli DNA polymerase V subunit exchange: a post-SOS mechanism to curtail error-prone DNA synthesis.	Shen X, Woodgate R, Goodman MF	2003
Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing.	Eoff RL, Angel KC, Egli M, Guengerich FP	2007
Protein-protein and protein-DNA interactions at the bacteriophage T4 DNA replication fork. Characterization of a fluorescently labeled DNA polymerase sliding clamp.	Sexton DJ, Carver TE, Berdis AJ, Benkovic SJ	1996
The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1.	Sluis-Cremer N, Arion D, Parikh U, Koontz D, Schinazi RF, Mellors JW, Parniak MA	2005
On the fidelity of DNA replication. Nucleoside monophosphate generation during polymerization.	Loeb LA, Dube DK, Beckman RA, Koplitz M, Gopinathan KP	1981
Lesion bypass activities of human DNA polymerase mu.	Zhang Y, Wu X, Guo D, Rechkoblit O, Taylor JS, Geacintov NE, Wang Z	2002
In vivo assembly of overproduced DNA polymerase III. Overproduction, purification, and characterization of the alpha, alpha-epsilon, and alpha-epsilon-theta subunits.	Kim DR, McHenry CS	1996
Inhibition of the 3' --> 5' exonuclease of human DNA polymerase epsilon by fludarabine-terminated DNA.	Kamiya K, Huang P, Plunkett W	1996
Apparent suicidal inactivation of DNA polymerase by adenosine 2',3'-riboepoxide 5'-triphosphate.	Abboud MM, Sim WJ, Loeb LA, Mildvan AS	1978
Enzymatic processing of uracil glycol, a major oxidative product of DNA cytosine.	Purmal AA, Lampman GW, Bond JP, Hatahet Z, Wallace SS	1998
Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta.	Beard WA, Osheroff WP, Prasad R, Sawaya MR, Jaju M, Wood TG, Kraut J, Kunkel TA, Wilson SH	1996
Beta*, a UV-inducible smaller form of the beta subunit sliding clamp of DNA polymerase III of Escherichia coli. I. Gene expression and regulation.	Paz-Elizur T, Skaliter R, Blumenstein S, Livneh Z	1996
DnaX complex of Escherichia coli DNA polymerase III holoenzyme. Central role of tau in initiation complex assembly and in determining the functional asymmetry of holoenzyme.	Dallmann HG, Thimmig RL, McHenry CS	1995
Escherichia coli DNA polymerase I (Klenow fragment) uses a hydrogen-bonding fork from Arg668 to the primer terminus and incoming deoxynucleotide triphosphate to catalyze DNA replication.	Meyer AS, Blandino M, Spratt TE	2004
Efficiency of correct nucleotide insertion governs DNA polymerase fidelity.	Beard WA, Shock DD, Vande Berg BJ, Wilson SH	2002
Protein-protein interactions in the bacteriophage T4 replisome. The leading strand holoenzyme is physically linked to the lagging strand holoenzyme and the primosome.	Ishmael FT, Trakselis MA, Benkovic SJ	2003
Subunit structure of mitochondrial DNA polymerase from Drosophila embryos. Physical and immunological studies.	Olson MW, Wang Y, Elder RH, Kaguni LS	1995
A conserved region in the amino terminus of DNA polymerase delta is involved in proliferating cell nuclear antigen binding.	Zhang SJ, Zeng XR, Zhang P, Toomey NL, Chuang RY, Chang LS, Lee MY	1995
Impairment of proliferating cell nuclear antigen-dependent apurinic/apyrimidinic site repair on linear DNA.	Biade S, Sobol RW, Wilson SH, Matsumoto Y	1998
A beta-like DNA polymerase from the mitochondrion of the trypanosomatid Crithidia fasciculata.	Torri AF, Kunkel TA, Englund PT	1994
Template-prime-dependent turnover of (Sp)-dATP alpha S by T4 DNA polymerase. The stereochemistry of the associated 3' goes to 5'-exonuclease.	Gupta A, DeBrosse C, Benkovic SJ	1982
Mutational studies of human DNA polymerase alpha. Identification of residues critical for deoxynucleotide binding and misinsertion fidelity of DNA synthesis.	Dong Q, Copeland WC, Wang TS	1993
Adenovirus DNA polymerase is phosphorylated by a stably associated histone H1 kinase.	Ramachandra M, Padmanabhan R	1993
Terminal deoxynucleotidyl transferase indiscriminately incorporates ribonucleotides and deoxyribonucleotides.	Boulé JB, Rougeon F, Papanicolaou C	2001
Enzymologic mechanism of calf thymus DNA polymerase delta.	Ng L, Tan CK, Downey KM, Fisher PA	1991
Primer terminus stabilization at the phi 29 DNA polymerase active site. Mutational analysis of conserved motif KXY.	Blasco MA, Méndez J, Lázaro JM, Blanco L, Salas M	1995
Fidelity of phi 29 DNA polymerase. Comparison between protein-primed initiation and DNA polymerization.	Esteban JA, Salas M, Blanco L	1993
The (I/Y)XGG motif of adenovirus DNA polymerase affects template DNA binding and the transition from initiation to elongation.	Brenkman AB, Heideman MR, Truniger V, Salas M, van der Vliet PC	2001
The application of a minicircle substrate in the study of the coordinated T4 DNA replication.	Yang J, Trakselis MA, Roccasecca RM, Benkovic SJ	2003
3'-->5' exonuclease in Drosophila mitochondrial DNA polymerase. Substrate specificity and functional coordination of nucleotide polymerization and mispair hydrolysis.	Olson MW, Kaguni LS	1992
Studies on the activator 1 protein complex, an accessory factor for proliferating cell nuclear antigen-dependent DNA polymerase delta.	Lee SH, Kwong AD, Pan ZQ, Hurwitz J	1991
DNA polymerase lambda, a novel DNA repair enzyme in human cells.	García-Díaz M, Bebenek K, Sabariegos R, Domínguez O, Rodríguez J, Kirchhoff T, García-Palomero E, Picher AJ, Juárez R, Ruiz JF, Kunkel TA, Blanco L	2002
Herpes simplex virus-specified DNA polymerase is the target for the antiviral action of 9-(2-phosphonylmethoxyethyl)adenine.	Foster SA, Cerny J, Cheng YC	1991
Primed and unprimed synthesis of poly (dA-dT) by calf thymus DNA polymerase alpha.	Henner D, Further JJ	1977
Kinetic analysis of nucleotide incorporation by mammalian DNA polymerase delta.	Einolf HJ, Guengerich FP	2000
Dissociation of the DNA polymerase III holoenzyme beta 2 subunits is accompanied by conformational change at distal cysteines 333.	Griep MA, McHenry CS	1990
Cell cycle-dependent phosphorylation of human DNA polymerase alpha.	Nasheuer HP, Moore A, Wahl AF, Wang TS	1991
Isolation, characterization, and expression in Escherichia coli of the DNA polymerase gene from Thermus aquaticus.	Lawyer FC, Stoffel S, Saiki RK, Myambo K, Drummond R, Gelfand DH	1989
Herpes simplex virus type 1 DNA polymerase. Mechanism of inhibition by acyclovir triphosphate.	Reardon JE, Spector T	1989
Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding.	Ren J, Nichols C, Bird LE, Fujiwara T, Sugimoto H, Stuart DI, Stammers DK	2000
Affinity labeling the DNA polymerase alpha complex. Identification of subunits containing the DNA polymerase active site and an important regulatory nucleotide-binding site.	Diffley JF	1988
Studies on the mechanism of Escherichia coli DNA polymerase I large fragment. Effect of template sequence and substrate variation on termination of synthesis.	Abbotts J, SenGupta DN, Zon G, Wilson SH	1988
Characterization of the polA gene of Streptococcus pneumoniae and comparison of the DNA polymerase I it encodes to homologous enzymes from Escherichia coli and phage T7.	Lopez P, Martinez S, Diaz A, Espinosa M, Lacks SA	1989
An auxiliary protein for DNA polymerase-delta from fetal calf thymus.	Tan CK, Castillo C, So AG, Downey KM	1986
Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides.	Fischhaber PL, Gerlach VL, Feaver WJ, Hatahet Z, Wallace SS, Friedberg EC	2002
Isolation, characterization, and kinetic properties of truncated forms of T4 DNA polymerase that exhibit 3'-5' exonuclease activity.	Lin TC, Karam G, Konigsberg WH	1994
Interaction of DNA polymerase and DNA helicase within the bacteriophage T4 DNA replication complex. Leading strand synthesis by the T4 DNA polymerase mutant A737V (tsL141) requires the T4 gene 59 helicase assembly protein.	Spacciapoli P, Nossal NG	1994
Biochemical characterization of mutant forms of DNA polymerase I from Escherichia coli. I. The polA12 mutation.	Uyemura D, Lehman IR	1976
The beta subunit modulates bypass and termination at UV lesions during in vitro replication with DNA polymerase III holoenzyme of Escherichia coli.	Shavitt O, Livneh Z	1989
DNA polymerase gamma from Xenopus laevis. I. The identification of a high molecular weight catalytic subunit by a novel DNA polymerase photolabeling procedure.	Insdorf NF, Bogenhagen DF	1989
Function and assembly of the bacteriophage T4 DNA replication complex: interactions of the T4 polymerase with various model DNA constructs.	Delagoutte E, von Hippel PH	2003
Saccharomyces cerevisiae replication factor C. I. Purification and characterization of its ATPase activity.	Yoder BL, Burgers PM	1991
Characterization of DNA replication at a restrictive temperature in a mouse DNA temperature-sensitive mutant, tsFT20 strain, containing heat-labile DNA polymerase alpha activity.	Eki T, Murakami Y, Enomoto T, Hanaoka F, Yamada M	1986
ATP activation of DNA polymerase III holoenzyme of Escherichia coli. I. ATP-dependent formation of an initiation complex with a primed template.	Burgers PM, Kornberg A	1982
A low molecular weight DNA polymerase from ovaries of the frog Xenopus laevis. DNA polymerase-beta (ovarian).	Joenje H, Benbow RM	1978
Enzymological characterization of DNA polymerase alpha. Basic catalytic properties processivity, and gap utilization of the homogeneous enzyme from human KB cells.	Fisher PA, Wang TS, Korn D	1979
Purification and characterization of an inducible Escherichia coli DNA polymerase capable of insertion and bypass at abasic lesions in DNA.	Bonner CA, Randall SK, Rayssiguier C, Radman M, Eritja R, Kaplan BE, McEntee K, Goodman MF	1988
Amino acid changes in a unique sequence of bacteriophage T7 DNA polymerase alter the processivity of nucleotide polymerization.	Yang XM, Richardson CC	1997
Increased activity and fidelity of DNA polymerase beta on single-nucleotide gapped DNA.	Chagovetz AM, Sweasy JB, Preston BD	1997
The J-helix of Escherichia coli DNA polymerase I (Klenow fragment) regulates polymerase and 3'- 5'-exonuclease functions.	Tuske S, Singh K, Kaushik N, Modak MJ	2000
Short gap-filling synthesis by DNA polymerase beta is processive.	Singhal RK, Wilson SH	1993
The T4 phage UvsW protein contains both DNA unwinding and strand annealing activities.	Nelson SW, Benkovic SJ	2007
DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine.	Zang H, Goodenough AK, Choi JY, Irimia A, Loukachevitch LV, Kozekov ID, Angel KC, Rizzo CJ, Egli M, Guengerich FP	2005
Metal binding to DNA polymerase I, its large fragment, and two 3',5'-exonuclease mutants of the large fragment.	Mullen GP, Serpersu EH, Ferrin LJ, Loeb LA, Mildvan AS	1990
Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4.	Zang H, Irimia A, Choi JY, Angel KC, Loukachevitch LV, Egli M, Guengerich FP	2006
Purification and properties of the deoxyribonucleic acid polymerase induced by vaccinia virus.	Challberg MD, Englund PT	1979
Purification and characterization of DNA polymerase III'. Identification of tau as a subunit of the DNA polymerase III holoenzyme.	McHenry CS	1982
Nucleotide sequence analysis of deoxyribonucleic acid. XIV. Conditions for the incorporation of ribonucleotides and deoxyribonucleotides into single-stranded areas of long double-stranded deoxyribonucleic acids.	Hamilton RT, Wu R	1974
A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease.	Spacciapoli P, Nossal NG	1994
Isolation of the DNA polymerase alpha core enzyme from mouse cells.	Prussak CE, Tseng BY	1987
Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins.	Bonner CA, Stukenberg PT, Rajagopalan M, Eritja R, O'Donnell ME, McEntee K, Echols H, Goodman MF	1992
Characterization of the two small subunits of Saccharomyces cerevisiae DNA polymerase delta.	Gerik KJ, Li X, Pautz A, Burgers PM	1998
DNA polymerase-primase from embryos of Drosophila melanogaster. The DNA polymerase subunit.	Cotterill S, Chui G, Lehman IR	1987
Yeast DNA primase and DNA polymerase activities. An analysis of RNA priming and its coupling to DNA synthesis.	Singh H, Brooke RG, Pausch MH, Williams GT, Trainor C, Dumas LB	1986
Structure and processivity of two forms of Saccharomyces cerevisiae DNA polymerase delta.	Burgers PM, Gerik KJ	1998
A function for the psi subunit in loading the Escherichia coli DNA polymerase sliding clamp.	Anderson SG, Williams CR, O'Donnell ME, Bloom LB	2007
Reconstitution of human DNA polymerase delta using recombinant baculoviruses: the p12 subunit potentiates DNA polymerizing activity of the four-subunit enzyme.	Podust VN, Chang LS, Ott R, Dianov GL, Fanning E	2002
Specificity of proofreading by the 3'----5' exonuclease of the DNA polymerase-primase of Drosophila melanogaster.	Reyland ME, Lehman IR, Loeb LA	1988
On the fidelity of DNA replication. Isolation of high fidelity DNA polymerase-primase complexes by immunoaffinity chromatography.	Reyland ME, Loeb LA	1987
Unique error signature of the four-subunit yeast DNA polymerase epsilon.	Shcherbakova PV, Pavlov YI, Chilkova O, Rogozin IB, Johansson E, Kunkel TA	2003
On the enzymatic basis for mutagenesis by manganese.	Goodman MF, Keener S, Guidotti S, Branscomb EW	1983
Long-patch base excision DNA repair of 2-deoxyribonolactone prevents the formation of DNA-protein cross-links with DNA polymerase beta.	Sung JS, DeMott MS, Demple B	2005
Functional roles of p12, the fourth subunit of human DNA polymerase delta.	Li H, Xie B, Zhou Y, Rahmeh AA, Trusa S, Zhang S, Gao Y, Lee EY, Lee MY	2006
Recognition and binding of template-primers containing defined abasic sites by Drosophila DNA polymerase alpha holoenzyme.	Ng L, Weiss SJ, Fisher PA	1989
Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA.	Copeland WC, Chen MS, Wang TS	1992
Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication.	Boudsocq F, Kokoska RJ, Plosky BS, Vaisman A, Ling H, Kunkel TA, Yang WW, Woodgate R	2004
DNA-thumb interactions and processivity of T7 DNA polymerase in comparison to yeast polymerase eta.	Cannistraro VJ, Taylor JS	2004
Analysis of a multicomponent thermostable DNA polymerase III replicase from an extreme thermophile.	Bruck I, Yuzhakov A, Yurieva O, Jeruzalmi D, Skangalis M, Kuriyan J, O'Donnell ME	2002
Proofreading activity of DNA polymerase III responds like elongation activity to auxiliary subunits.	Reems JA, Griep MA, McHenry CS	1991
ATP-independent loading of the proliferating cell nuclear antigen requires DNA ends.	Burgers PM, Yoder BL	1993
Role of the C-terminal residue of the DNA polymerase of bacteriophage T7.	Kumar JK, Tabor S, Richardson CC	2001
Essential role of Sna41/Cdc45 in loading of DNA polymerase alpha onto minichromosome maintenance proteins in fission yeast.	Uchiyama M, Griffiths D, Arai K, Masai H	2001
Translesion DNA synthesis by yeast DNA polymerase eta on templates containing N2-guanine adducts of 1,3-butadiene metabolites.	Minko IG, Washington MT, Prakash L, Prakash S, Lloyd RS	2001
The K65R mutation confers increased DNA polymerase processivity to HIV-1 reverse transcriptase.	Arion D, Borkow G, Gu Z, Wainberg MA, Parniak MA	1996
DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change.	Vande Berg BJ, Beard WA, Wilson SH	2001
Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4.	Eoff RL, Irimia A, Angel KC, Egli M, Guengerich FP	2007
A unique organization of the protein subunits of the DNA polymerase clamp loader in the archaeon Methanobacterium thermoautotrophicum deltaH.	Kelman Z, Hurwitz J	2000
dNTP binding to HIV-1 reverse transcriptase and mammalian DNA polymerase beta as revealed by affinity labeling with a photoreactive dNTP analog.	Lavrik OI, Prasad R, Beard WA, Safronov IV, Dobrikov MI, Srivastava DK, Shishkin GV, Wood TG, Wilson SH	1996
Bacteriophage T4 gene expression. Evidence for two classes of prereplicative cistrons.	O'Farrell PZ, Gold L	1973
Affinity labeling of Escherichia coli DNA polymerase I by 5'-fluorosulfonylbenzoyladenosine. Identification of the domain essential for polymerization and Arg-682 as the site of reactivity.	Pandey VN, Modak MJ	1988
Gene 4 protein of bacteriophage T7. Characterization of the product synthesized by the T7 DNA polymerase and gene 4 protein in the absence of ribonucleoside 5'-triphosphates.	Kolodner R, Richardson CC	1978
DNA polymerase II (epsilon) of Saccharomyces cerevisiae dissociates from the DNA template by sensing single-stranded DNA.	Maki S, Hashimoto K, Ohara T, Sugino A	1998
The proofreading pathway of bacteriophage T4 DNA polymerase.	Reha-Krantz LJ, Marquez LA, Elisseeva E, Baker RP, Bloom LB, Dunford HB, Goodman MF	1998
In vivo assembly of the tau-complex of the DNA polymerase III holoenzyme expressed from a five-gene artificial operon. Cleavage of the tau-complex to form a mixed gamma-tau-complex by the OmpT protease.	Pritchard AE, Dallmann HG, McHenry CS	1996
The rapid dissociation of the T4 DNA polymerase holoenzyme when stopped by a DNA hairpin helix. A model for polymerase release following the termination of each Okazaki fragment.	Hacker KJ, Alberts BM	1994
Expression and characterization of the small subunit of human DNA polymerase delta.	Sun Y, Jiang Y, Zhang P, Zhang SJ, Zhou Y, Li BQ, Toomey NL, Lee MY	1997
Schizosaccharomyces pombe proliferating cell nuclear antigen mutations affect DNA polymerase delta processivity.	Arroyo MP, Downey KM, So AG, Wang TS	1996
Rapid hydrolysis of deoxynucleoside triphosphates accompanies DNA synthesis by T4 DNA polymerase and T4 accessory proteins 44/62 and 45.	Roth AC, Nossal NG, Englund PT	1982
The isolation and characterization of DNA polymerase alpha from spinach.	Misumi M, Weissbach A	1982
Beta*, a UV-inducible shorter form of the beta subunit of DNA polymerase III of Escherichia coli. II. Overproduction, purification, and activity as a polymerase processivity clamp.	Skaliter R, Bergstein M, Livneh Z	1996
Escherichia coli DNA polymerase III holoenzyme subunits alpha, beta, and gamma directly contact the primer-template.	Reems JA, Wood S, McHenry CS	1995
Functional analysis of multiple single-stranded DNA-binding proteins from Methanosarcina acetivorans and their effects on DNA synthesis by DNA polymerase BI.	Robbins JB, Murphy MC, White BA, Mackie RI, Ha T, Cann IK	2004
Crystal structure of the herpes simplex virus 1 DNA polymerase.	Liu S, Knafels JD, Chang JS, Waszak GA, Baldwin ET, Deibel MR, Thomsen DR, Homa FL, Wells PA, Tory MC, Poorman RA, Gao H, Qiu X, Seddon AP	2006
Properties of the 3' to 5' exonuclease associated with porcine liver DNA polymerase gamma. Substrate specificity, product analysis, inhibition, and kinetics of terminal excision.	Longley MJ, Mosbaugh DW	1991
Overexpression, purification, and characterization of Escherichia coli bacteriophage PRD1 DNA polymerase. In vitro synthesis of full-length PRD1 DNA with purified proteins.	Savilahti H, Caldentey J, Lundström K, Syväoja JE, Bamford DH	1991
Mechanism of T5-induced DNA polymerase. II. Characterization of the dead-end complex.	Das SK, Fujimura RK	1977
Characterization of bacteriophage T7 DNA polymerase purified to homogeneity by antithioredoxin immunoadsorbent chromatography.	Nordström B, Randahl H, Slaby I, Holmgren A	1981
Ability of polymerase eta and T7 DNA polymerase to bypass bulge structures.	Cannistraro VJ, Taylor JS	2007
RNA priming of DNA replication by bacteriophage T4 proteins.	Nossal NG	1980
The pyrophosphate analogue foscarnet traps the pre-translocational state of HIV-1 reverse transcriptase in a Brownian ratchet model of polymerase translocation.	Marchand B, Tchesnokov EP, Götte M	2007
Novel mechanism of inhibition of HIV-1 reverse transcriptase by a new non-nucleoside analog, KM-1.	Wang LZ, Kenyon GL, Johnson KA	2004
Specific sequences in native DNA that arrest synthesis by DNA polymerase alpha.	Weaver DT, DePamphilis ML	1982
DNA polymerase-alpha. Common polypeptide core structure of three enzyme forms from human KB cells.	Filpula D, Fisher PA, Korn D	1982
The initial step of in vitro synthesis of deoxyribonucleic acid by the T4 deoxyribonucleic acid polymerase.	Englund PT	1971
Sequence-specific pausing during in vitro DNA replication on double-stranded DNA templates.	Bedinger P, Munn M, Alberts BM	1989
Bacteriophage T4 RNase H removes both RNA primers and adjacent DNA from the 5' end of lagging strand fragments.	Bhagwat M, Nossal NG	2001
Translesion synthesis across O6-alkylguanine DNA adducts by recombinant human DNA polymerases.	Choi JY, Chowdhury G, Zang H, Angel KC, Vu CC, Peterson LA, Guengerich FP	2006
Novel role of base excision repair (BER) in mediating cisplatin cytotoxicity.	Kothandapani A, Dangeti VS, Brown AR, Banze LA, Wang XH, Sobol RW, Patrick SM	2011
Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae pol epsilon and its unexpected ability to support growth in the absence of the DNA polymerase domain.	Dua R, Levy DL, Campbell JL	1999
Fidelity of Escherichia coli DNA polymerase III holoenzyme. The effects of beta, gamma complex processivity proteins and epsilon proofreading exonuclease on nucleotide misincorporation efficiencies.	Bloom LB, Chen X, Fygenson DK, Turner J, O'Donnell ME, Goodman MF	1997
Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase.	Fisher TS, Prasad VR	2002
Proliferating cell nuclear antigen promotes misincorporation catalyzed by calf thymus DNA polymerase delta.	Mozzherin DJ, McConnell M, Jasko MV, Krayevsky AA, Tan CK, Downey KM, Fisher PA	1996
On the fidelity of DNA replication. Lack of exodeoxyribonuclease activity and error-correcting function in avian myeloblastosis virus DNA polymerase.	Battula N, Loeb LA	1976
The bacteriophage T4 DNA replication fork. Only DNA helicase is required for leading strand DNA synthesis by the DNA polymerase holoenzyme.	Cha TA, Alberts BM	1989
The influence of the proliferating cell nuclear antigen-interacting domain of p21(CIP1) on DNA synthesis catalyzed by the human and Saccharomyces cerevisiae polymerase delta holoenzymes.	Gibbs E, Kelman Z, Gulbis JM, O'Donnell ME, Kuriyan J, Burgers PM, Hurwitz J	1997
Poliovirus RNA-dependent RNA polymerase (3Dpol) is sufficient for template switching in vitro.	Arnold JJ, Cameron CE	1999
Site-directed mutagenesis of arginine 72 of HIV-1 reverse transcriptase. Catalytic role and inhibitor sensitivity.	Sarafianos SG, Pandey VN, Kaushik N, Modak MJ	1995
Glutamate overcomes the salt inhibition of DNA polymerase III holoenzyme.	Griep MA, McHenry CS	1989
Interaction of herpes simplex virus-induced DNA polymerase with 9-(1,3-dihydroxy-2-propoxymethyl)guanine triphosphate.	Frank KB, Chiou JF, Cheng YC	1984
Two types of replication proteins increase the rate at which T4 DNA polymerase traverses the helical regions in a single-stranded DNA template.	Huang CC, Hearst JE, Alberts BM	1981
Human immunodeficiency virus 1 reverse transcriptase. Template binding, processivity, strand displacement synthesis, and template switching.	Huber HE, McCoy JM, Seehra JS, Richardson CC	1989
Evolution of RNA-binding specificity in T4 DNA polymerase.	Wang CC, Pavlov A, Karam JD	1997
Transcription and translation of prereplicative bacteriophage T4 genes in vitro.	O'Farrell PZ, Gold L	1973
Architecture of the bacteriophage T4 replication complex revealed with nanoscale biopointers.	Nossal NG, Makhov AM, Chastain PD, Jones CE, Griffith JD	2007
DNA replication by bacteriophage T4 proteins. The T4 43, 32, 44--62, And 45 proteins are required for strand displacement synthesis at nicks in duplex DNA.	Nossal NG, Peterlin BM	1979
Structural and functional organization of the DNA polymerase of bacteriophage T7.	Yang X, Richardson CC	1996
Importance of the N-terminal region of the phage GA-1 single-stranded DNA-binding protein for its self-interaction ability and functionality.	Gascón I, Carrascosa JL, Villar L, Lázaro JM, Salas M	2002
Escherichia coli DNA polymerase II is stimulated by DNA polymerase III holoenzyme auxiliary subunits.	Hughes AJ, Bryan SK, Chen H, Moses RE, McHenry CS	1991
Participation of the fingers subdomain of Escherichia coli DNA polymerase I in the strand displacement synthesis of DNA.	Singh K, Srivastava A, Patel SS, Modak MJ	2007
The C-terminal residues of bacteriophage T7 gene 4 helicase-primase coordinate helicase and DNA polymerase activities.	Lee SJ, Marintcheva B, Hamdan SM, Richardson CC	2006
Properties of purified enzymes induced by pathogenic drug-resistant mutants of herpes simplex virus. Evidence for virus variants expressing normal DNA polymerase and altered thymidine kinase.	Larder BA, Derse D, Cheng YC, Darby G	1983
Excision repair and DNA synthesis with a combination of HeLa DNA polymerase beta and DNase V.	Mosbaugh DW, Linn S	1983
DNA primase isolated from the yeast DNA primase-DNA polymerase complex. Immunoaffinity purification and analysis of RNA primer synthesis.	Brooks M, Dumas LB	1989
DNA polymerase III holoenzyme of Escherichia coli. III. Distinctive processive polymerases reconstituted from purified subunits.	Maki S, Kornberg A	1988
Interactions of the DNA polymerase and gene 4 protein of bacteriophage T7. Protein-protein and protein-DNA interactions involved in RNA-primed DNA synthesis.	Nakai H, Richardson CC	1986
DNA repair synthesis in human fibroblasts requires DNA polymerase delta.	Nishida C, Reinhard P, Linn S	1988
Analysis of nucleotide sequences at 3' termini of duplex deoxyribonucleic acid with the use of the T4 deoxyribonucleic acid polymerase.	Englund PT	1971
Exonuclease activity associated with a multiprotein form of HeLa cell DNA polymerase alpha. Purification and properties of the exonuclease.	Skarnes W, Bonin P, Baril E	1986
Interaction between the DNA polymerase and single-stranded DNA-binding protein (infected cell protein 8) of herpes simplex virus 1.	O'Donnell ME, Elias P, Funnell BE, Lehman IR	1987
Properties of initiation complexes formed between Escherichia coli DNA polymerase III holoenzyme and primed DNA in the absence of ATP.	Kwon-Shin O, Bodner JB, McHenry CS, Bambara RA	1987
Purification and characterization of the beta subunit of the DNA polymerase III holoenzyme of Escherichia coli.	Johanson KO, McHenry CS	1980
Aphidicolin, a specific inhibitor of DNA polymerase alpha, inhibits conversion of lanosterol to C-27 sterols in mouse L cells.	Leonard DA, Chen HW	1984
Motif A of bacteriophage T4 DNA polymerase: role in primer extension and DNA replication fidelity. Isolation of new antimutator and mutator DNA polymerases.	Reha-Krantz LJ, Nonay RL	1994
Kinetic analysis of correct nucleotide insertion by a Y-family DNA polymerase reveals conformational changes both prior to and following phosphodiester bond formation as detected by tryptophan fluorescence.	Beckman JW, Wang Q, Guengerich FP	2008
Biotin tagging deletion analysis of domain limits involved in protein-macromolecular interactions. Mapping the tau binding domain of the DNA polymerase III alpha subunit.	Kim DR, McHenry CS	1996
Enzymological characterization of KB cell DNA polymerase-alpha. Regulation of template binding by nucleic acid base composition.	Fisher PA, Chen JT, Korn D	1981
Eukaryotic DNA polymerase alpha. Structural analysis of the enzyme from regenerating rat liver.	Mechali M, Abadiedebat J, de Recondo AM	1980
Contrasting effects of Escherichia coli single-stranded DNA binding protein on synthesis by T7 DNA polymerase and Escherichia coli DNA polymerase I (large fragment). Evidence that binding protein inhibits trans-lesion synthesis by polymerase I.	Michaels ML, Lee MS, Romano LJ	1986
DNA polymerase III from Saccharomyces cerevisiae. I. Purification and characterization.	Bauer GA, Heller HM, Burgers PM	1988
Complete replication of templates by Escherichia coli DNA polymerase III holoenzyme.	O'Donnell ME, Kornberg A	1985
The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication.	Reuven NB, Arad G, Maor-Shoshani A, Livneh Z	1999
Elongation of RNA-primed DNA templates by DNA polymerase alpha from Drosophila melanogaster embryos.	Villani G, Fay PJ, Bambara RA, Lehman IR	1981
Studies on the mechanism of DNA polymerase alpha. Nascent chain elongation, steady state kinetics, and the initiation phase of DNA synthesis.	Detera SD, Becerra SP, Swack JA, Wilson SH	1981
A unique region in bacteriophage t7 DNA polymerase important for exonucleolytic hydrolysis of DNA.	Kumar JK, Chiu ET, Tabor S, Richardson CC	2004
A molecular handoff between bacteriophage T7 DNA primase and T7 DNA polymerase initiates DNA synthesis.	Kato M, Ito T, Wagner G, Ellenberger T	2004
Proliferating cell nuclear antigen recruits cyclin-dependent kinase inhibitor Xic1 to DNA and couples its proteolysis to DNA polymerase switching.	Chuang LC, Yew PR	2005
Cell cycle-dependent phosphorylation of the DNA polymerase epsilon subunit, Dpb2, by the Cdc28 cyclin-dependent protein kinase.	Kesti T, McDonald WH, Yates JR, Wittenberg C	2004
Properties of overexpressed phage T5 D15 exonuclease. Similarities with Escherichia coli DNA polymerase I 5'-3' exonuclease.	Sayers JR, Eckstein F	1990
DNA primase-DNA polymerase alpha from simian cells. Modulation of RNA primer synthesis by ribonucleoside triphosphates.	Yamaguchi M, Hendrickson EA, DePamphilis ML	1985
Cut5 is required for the binding of Atr and DNA polymerase alpha to genotoxin-damaged chromatin.	Parrilla-Castellar ER, Karnitz LM	2003
Trypanosoma brucei has two distinct mitochondrial DNA polymerase beta enzymes.	Saxowsky TT, Choudhary G, Klingbeil MM, Englund PT	2003
Effect of calcium on the recovery and distribution of DNA polymerase alpha from cultured human cells.	Eichler DC, Fisher PA, Korn D	1977
A low molecular weight DNA polymerase beta in the sea urchin Strongylocentrotus purpurantus. Partial purification, properties, and changes in development.	Hobart PM, Infante AA	1978
The primase activity of DNA polymerase alpha from calf thymus.	Grosse F, Krauss G	1985
DNA polymerase lambda protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair.	Braithwaite EK, Kedar PS, Lan L, Polosina YY, Asagoshi K, Poltoratsky VP, Horton JK, Miller H, Teebor GW, Yasui A, Wilson SH	2005
DNA polymerase III accessory proteins. IV. Characterization of chi and psi.	Xiao H, Dong Z, O'Donnell ME	1993
Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen.	Kedar PS, Kim SJ, Robertson A, Hou EW, Prasad R, Horton JK, Wilson SH	2002
The DNA polymerase domain of pol(epsilon) is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae.	Ohya T, Kawasaki Y, Hiraga S, Kanbara S, Nakajo K, Nakashima N, Suzuki A, Sugino A	2002
The hydrophobic hinge region of rat DNA polymerase beta is critical for substrate binding pocket geometry.	Starcevic D, Dalal S, Jaeger J, Sweasy JB	2005
A Mutation in the gene-encoding bacteriophage T7 DNA polymerase that renders the phage temperature-sensitive.	Kumar JK, Kremsdorf R, Tabor S, Richardson CC	2001
Further characterization of human DNA polymerase delta interacting protein 38.	Xie B, Li H, Wang Q, Xie S, Rahmeh AA, Dai W, Lee MY	2005
Base stacking and even/odd behavior of hairpin loops in DNA triplet repeat slippage and expansion with DNA polymerase.	Hartenstine MJ, Goodman MF, Petruska J	2000
A mutant thioredoxin from Escherichia coli tsnC 7007 that is nonfunctional as subunit of phage T7 DNA polymerase.	Holmgren A, Kallis GB, Nordström B	1981
The efficiency and specificity of apurinic/apyrimidinic site bypass by human DNA polymerase eta and Sulfolobus solfataricus Dpo4.	Kokoska RJ, McCulloch SD, Kunkel TA	2003
A preformed, topologically stable replication fork. Characterization of leading strand DNA synthesis catalyzed by T7 DNA polymerase and T7 gene 4 protein.	Lechner RL, Richardson CC	1983
Impaired mismatch extension by a herpes simplex DNA polymerase mutant with an editing nuclease defect.	Baker RO, Hall JD	1998
ATP binding to the Escherichia coli clamp loader powers opening of the ring-shaped clamp of DNA polymerase III holoenzyme.	Hingorani MM, O'Donnell ME	1998
Two Epstein-Barr virus-associated DNA polymerase activities.	Goodman SR, Prezyna C, Benz WC	1978
Size classes of products synthesized processively by two subassemblies of Escherichia coli DNA polymerase III holoenzyme.	Fay PJ, Johanson KO, McHenry CS, Bambara RA	1982
Chick embryo DNA polymerase beta. Purified enzyme consists of a single Mr = 40,000 polypeptide.	Yamaguchi M, Tanabe K, Taguchi YN, Nishizawa M, Takahashi T, Matsukage A	1980
Misincorporation of nucleotides by calf thymus DNA primase and elongation of primers containing multiple noncognate nucleotides by DNA polymerase alpha.	Sheaff RJ, Kuchta RD	1994
Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota.	Vidal AE, Kannouche PL, Podust VN, Yang WW, Lehmann AR, Woodgate R	2004
Dynamics of termination during in vitro replication of ultraviolet-irradiated DNA with DNA polymerase III holoenzyme of Escherichia coli.	Shwartz H, Livneh Z	1987
Induction of Epstein-Barr virus-associated DNA polymerase by 12-O-tetradecanoylphorbol-13-acetate. Purification and characterization.	Datta AK, Feighny RJ, Pagano JS	1980
Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping.	Hu HY, Horton JK, Gryk MR, Prasad R, Naron JM, Sun DA, Hecht SM, Wilson SH, Mullen GP	2004
Termination within oligo(dT) tracts in template DNA by DNA polymerase gamma occurs with formation of a DNA triplex structure and is relieved by mitochondrial single-stranded DNA-binding protein.	Mikhailov VS, Bogenhagen DF	1996
DNA polymerase III holoenzyme of Escherichia coli. I. Purification and distinctive functions of subunits tau and gamma, the dnaZX gene products.	Maki S, Kornberg A	1988
Accessory proteins bind a primed template and mediate rapid cycling of DNA polymerase III holoenzyme from Escherichia coli.	O'Donnell ME	1987
Exposure of HeLa DNA polymerase alpha to protein kinase C affects its catalytic properties.	Krauss SW, Mochly-Rosen D, Koshland DE, Linn S	1987
Enzymatic synthesis of deoxyribonucleic acid. XXVI. Physical and chemical studies of a homogeneous deoxyribonucleic acid polymerase.	Jovin TM, Englund PT, Bertsch LL	1969
Structural and enzymological characterization of immunoaffinity-purified DNA polymerase alpha.DNA primase complex from KB cells.	Wong SW, Paborsky LR, Fisher PA, Wang TS, Korn D	1986
Requirements for synthesis of ribonucleic acid primers during lagging strand synthesis by the DNA polymerase and gene 4 protein of bacteriophage T7.	Romano LJ, Richardson CC	1979
Selective oxidation of the exonuclease domain of bacteriophage T7 DNA polymerase.	Tabor S, Richardson CC	1987
Mechanism of translesion DNA synthesis by DNA polymerase II. Comparison to DNA polymerases I and III core.	Paz-Elizur T, Takeshita M, Goodman M, O'Donnell ME, Livneh Z	1996
Contribution of the 3'- to 5'-exonuclease activity of herpes simplex virus type 1 DNA polymerase to the fidelity of DNA synthesis.	Song L, Chaudhuri M, Knopf CW, Parris DS	2004
Secretion of thermostable DNA polymerase using a novel baculovirus vector.	Mroczkowski BS, Huvar A, Lernhardt W, Misono K, Nielson K, Scott B	1994
Mechanism of stimulation of T7 DNA polymerase by Escherichia coli single-stranded DNA binding protein (SSB).	Myers TW, Romano LJ	1988
Influence of DNA structure on DNA polymerase beta active site function: extension of mutagenic DNA intermediates.	Beard WA, Shock DD, Wilson SH	2004
Bacillus subtilis bacteriophage PBS2-induced DNA polymerase. Its purification and assay characteristics.	Hitzeman RA, Price AR	1978
Eukaryotic DNA polymerases: proposal for a revised nomenclature.	Burgers PM, Koonin EV, Bruford E, Blanco L, Burtis KC, Christman MF, Copeland WC, Friedberg EC, Hanaoka F, Hinkle DC, Lawrence CW, Nakanishi M, Ohmori H, Prakash L, Prakash S, Reynaud CA, Sugino A, Todo T, Wang Z, Weill JC, Woodgate R	2001
Interplay of clamp loader subunits in opening the beta sliding clamp of Escherichia coli DNA polymerase III holoenzyme.	Leu FP, O'Donnell ME	2001
Modulation of hyperthermophilic DNA polymerase activity by archaeal chromatin proteins.	Lou H, Duan Z, Huo X, Huang L	2004
Release of the hepatitis B virus-associated DNA polymerase from the viral particle by the proteolytic cleavage.	Shin HJ, Rho HM	1995
Bacteriophage T4 DNA replication protein 41. Cloning of the gene and purification of the expressed protein.	Hinton DM, Silver LL, Nossal NG	1985
Single-stranded DNA-binding protein recruits DNA polymerase V to primer termini on RecA-coated DNA.	Arad G, Hendel A, Urbanke C, Curth U, Livneh Z	2008
Increased catalytic activity and altered fidelity of human DNA polymerase iota in the presence of manganese.	Frank EG, Woodgate R	2007
Physiological and biochemical defects in functional interactions of mitochondrial DNA polymerase and DNA-binding mutants of single-stranded DNA-binding protein.	Farr CL, Matsushima Y, Lagina AT, Luo N, Kaguni LS	2004
Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts.	Lee JY, Blanco L, Zhou T, Garcia-Diaz M, Bebenek K, Kunkel TA, Wang Z, Povirk LF	2004
Inteins of Thermococcus fumicolans DNA polymerase are endonucleases with distinct enzymatic behaviors.	Saves I, Ozanne V, Dietrich J, Masson JM	2000
Inactivation of avian myeloblastosis virus DNA polymerase by specific binding of pyridoxal 5'-phosphate to deoxynucleoside triphosphate binding site.	Papas TS, Pry TW, Marciani DJ	1977
The effect of DNA structure on the catalytic efficiency and fidelity of human DNA polymerase beta on templates with platinum-DNA adducts.	Vaisman A, Warren MW, Chaney SG	2001
Human papillomavirus DNA replication. Interactions between the viral E1 protein and two subunits of human dna polymerase alpha/primase.	Conger KL, Liu JS, Kuo SR, Chow LT, Wang TS	1999
Proofreading of DNA polymerase eta-dependent replication errors.	Bebenek K, Matsuda T, Masutani C, Hanaoka F, Kunkel TA	2001
The DnaX-binding subunits delta' and psi are bound to gamma and not tau in the DNA polymerase III holoenzyme.	Glover BP, McHenry CS	2000
The base substitution fidelity of DNA polymerase beta-dependent single nucleotide base excision repair.	Matsuda T, Vande Berg BJ, Bebenek K, Osheroff WP, Wilson SH, Kunkel TA	2003
A covalent linkage between the gene 5 DNA polymerase of bacteriophage T7 and Escherichia coli thioredoxin, the processivity factor: fate of thioredoxin during DNA synthesis.	Johnson DE, Richardson CC	2003
Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase epsilon.	Kesti T, Frantti H, Syväoja JE	1993
Inducible expression of a dominant negative DNA polymerase-gamma depletes mitochondrial DNA and produces a rho0 phenotype.	Jazayeri M, Andreyev A, Will Y, Ward M, Anderson CM, Clevenger W	2003
Involvement of DNA polymerase alpha in simian virus 40 DNA replication.	Edenberg HJ, Anderson S, DePamphilis ML	1978
The herpes simplex virus type 1 DNA polymerase processivity factor increases fidelity without altering pre-steady-state rate constants for polymerization or excision.	Chaudhuri M, Song L, Parris DS	2003
DNA polymerase III accessory proteins. V. Theta encoded by holE.	Studwell-Vaughan PS, O'Donnell ME	1993
A role for DNA polymerase beta in mutagenic UV lesion bypass.	Servant L, Cazaux C, Bieth A, Iwai S, Hanaoka F, Hoffmann JS	2002
A novel functional domain of an alpha-like DNA polymerase. The binding site on the herpes simplex virus polymerase for the viral UL42 protein.	Digard P, Coen DM	1990
DNA polymerase I-mediated ultraviolet repair synthesis in toluene-treated Escherichia coli.	Dorson JW, Moses RE	1978
Loss of DNA polymerase beta stacking interactions with templating purines, but not pyrimidines, alters catalytic efficiency and fidelity.	Beard WA, Shock DD, Yang XP, DeLauder SF, Wilson SH	2002
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda.	Mizushina Y, Kamisuki S, Kasai N, Shimazaki N, Takemura M, Asahara H, Linn S, Yoshida S, Matsukage A, Koiwai O, Sugawara F, Yoshida H, Sakaguchi K	2002
DNA polymerase III accessory proteins. III. holC and holD encoding chi and psi.	Xiao H, Crombie R, Dong Z, Onrust R, O'Donnell ME	1993
DNA polymerase beta -mediated long patch base excision repair. Poly(ADP-ribose)polymerase-1 stimulates strand displacement DNA synthesis.	Prasad R, Lavrik OI, Kim SJ, Kedar P, Yang XP, Vande Berg BJ, Wilson SH	2001
Human DNA polymerase iota promiscuous mismatch extension.	Vaisman A, Tissier A, Frank EG, Goodman MF, Woodgate R	2001
Invariant Asp-1122 and Asp-1124 are essential residues for polymerization catalysis of family D DNA polymerase from Pyrococcus horikoshii.	Shen Y, Musti K, Hiramoto M, Kikuchi H, Kawarabayashi Y, Matsui I	2001
Energetics and specificity of Rat DNA polymerase beta interactions with template-primer and gapped DNA substrates.	Jezewska MJ, Rajendran S, Bujalowski W	2001
Replication protein A as a "fidelity clamp" for DNA polymerase alpha.	Maga G, Frouin I, Spadari S, Hubscher U	2001
Biochemical analysis of point mutations in the 5'-3' exonuclease of DNA polymerase I of Streptococcus pneumoniae. Functional and structural implications.	Amblar M, de Lacoba MG, Corrales MA, Lopez P	2001
Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon.	Li Y, Pursell ZF, Linn S	2000
The efficiency and fidelity of translesion synthesis past cisplatin and oxaliplatin GpG adducts by human DNA polymerase beta.	Vaisman A, Chaney SG	2000
Mapping of the 5'-2-deoxyribose-5-phosphate lyase active site in DNA polymerase beta by mass spectrometry.	Deterding LJ, Prasad R, Mullen GP, Wilson SH, Tomer KB	2000
Structure and activity associated with multiple forms of Schizosaccharomyces pombe DNA polymerase delta.	Zuo S, Bermudez V, Zhang G, Kelman Z, Hurwitz J	2000
Proliferating cell nuclear antigen promotes translesion synthesis by DNA polymerase zeta.	Garg P, Stith CM, Majka J, Burgers PM	2005
Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase beta (Pol4)-dependent pathway.	Wilson TE, Lieber MR	1999
Role of DNA polymerase beta in the excision step of long patch mammalian base excision repair.	Dianov GL, Prasad R, Wilson SH, Bohr VA	1999
Primase activity of human DNA polymerase alpha-primase. Divalent cations stabilize the enzyme activity of the p48 subunit.	Schneider A, Smith RW, Kautz AR, Weisshart K, Grosse F, Nasheuer HP	1998
Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5'-deoxyribose phosphate lyase activities.	Prasad R, Beard WA, Chyan JY, Maciejewski MW, Mullen GP, Wilson SH	1998
Structural analyses of gp45 sliding clamp interactions during assembly of the bacteriophage T4 DNA polymerase holoenzyme. II. The Gp44/62 clamp loader interacts with a single defined face of the sliding clamp ring.	Latham GJ, Bacheller DJ, Pietroni P, von Hippel PH	1997
On the processive mechanism of Escherichia coli DNA Polymerase I. The polA5 mutation.	Matson SW, Capaldo-Kimball FN, Bambara RA	1978
Role of the core DNA polymerase III subunits at the replication fork. Alpha is the only subunit required for processive replication.	Marians KJ, Hiasa H, Kim DR, McHenry CS	1998
Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon.	Li Y, Asahara H, Patel VS, Zhou S, Linn S	1997
Requirement of yeast DNA polymerase delta in post-replicational repair of UV-damaged DNA.	Torres-Ramos CA, Prakash S, Prakash L	1997
Replication of template-primers containing propanodeoxyguanosine by DNA polymerase beta. Induction of base pair substitution and frameshift mutations by template slippage and deoxynucleoside triphosphate stabilization.	Hashim MF, Schnetz-Boutaud N, Marnett LJ	1997
Replication across O6-methylguanine by human DNA polymerase beta in vitro. Insights into the futile cytotoxic repair and mutagenesis of O6-methylguanine.	Singh J, Su L, Snow ET	1996
The development and use of a DNA polymerase arrest assay for the evaluation of parameters affecting intrastrand tetraplex formation.	Weitzmann MN, Woodford KJ, Usdin K	1996
DnaX complex of Escherichia coli DNA polymerase III holoenzyme. The chi psi complex functions by increasing the affinity of tau and gamma for delta.delta' to a physiologically relevant range.	Olson MW, Dallmann HG, McHenry CS	1995
DNA polymerases: structural diversity and common mechanisms.	Steitz TA	1999
Structural and functional homology between mammalian DNase IV and the 5'-nuclease domain of Escherichia coli DNA polymerase I.	Robins P, Pappin DJ, Wood RD, Lindahl T	1994
Purification and characterization of a new DNA polymerase from budding yeast Saccharomyces cerevisiae. A probable homolog of mammalian DNA polymerase beta.	Shimizu K, Santocanale C, Ropp PA, Longhese MP, Plevani P, Lucchini G, Sugino A	1993
Isolation and characterization of DNA polymerase epsilon from the silk glands of Bombyx mori.	Niranjanakumari S, Gopinathan KP	1993
The use of Taq DNA polymerase to determine the sequence specificity of DNA damage caused by cis-diamminedichloroplatinum(II), acridine-tethered platinum(II) diammine complexes or two analogues.	Murray V, Motyka H, England PR, Wickham G, Lee HH, Denny WA, McFadyen WD	1992
DNA polymerase-delta from the silk glands of Bombyx mori.	Niranjanakumari S, Gopinathan KP	1992
Fluorescence energy transfer between the primer and the beta subunit of the DNA polymerase III holoenzyme.	Griep MA, McHenry CS	1992
DNA polymerase III holoenzyme. Components, structure, and mechanism of a true replicative complex.	McHenry CS	1991
On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation.	Hershfield MS	1973
Specificity and enzymatic mechanism of the editing exonuclease of Escherichia coli DNA polymerase III.	Brenowitz S, Kwack S, Goodman MF, O'Donnell ME, Echols H	1991
Characterization of human DNA polymerase delta and its immunochemical relationships with DNA polymerase alpha and epsilon.	Lee MY, Jiang YQ, Zhang SJ, Toomey NL	1991
Strand displacement during deoxyribonucleic acid synthesis at single strand breaks.	Masamune Y, Richardson CC	1971
Studies of the domain structure of mammalian DNA polymerase beta. Identification of a discrete template binding domain.	Kumar A, Widen SG, Williams KR, Kedar P, Karpel RL, Wilson SH	1990
Functional human mitochondrial DNA polymerase gamma forms a heterotrimer.	Yakubovskaya E, Chen Z, Carrodeguas JA, Kisker C, Bogenhagen DF	2006
Purification and properties of mosquito DNA polymerase.	Mastropaolo W, Lang CA	1978
Herpes simplex virus type 1 and human DNA polymerase interactions with 2'-deoxyguanosine 5'-triphosphate analogues. Kinetics of incorporation into DNA and induction of inhibition.	Reardon JE	1989
In vitro replication of mitochondrial DNA. Elongation of the endogenous primer sequence in D loop mitochondrial DNA by human DNA polymerase beta.	Eichler DC, Wang TS, Clayton DA, Korn D	1977
Mutational studies of human DNA polymerase alpha. Lysine 950 in the third most conserved region of alpha-like DNA polymerases is involved in binding the deoxynucleoside triphosphate.	Dong Q, Wang TS	1995
Affinity labeling the DNA polymerase alpha complex. I. Pyridoxal 5'-phosphate inhibition of DNA polymerase and DNA primase activities of the DNA polymerase alpha complex from Drosophila melanogaster embryos.	Diffley JF	1988
Mechanism of replication of ultraviolet-irradiated single-stranded DNA by DNA polymerase III holoenzyme of Escherichia coli. Implications for SOS mutagenesis.	Livneh Z	1986
3'-->5' exonuclease active site of phi 29 DNA polymerase. Evidence favoring a metal ion-assisted reaction mechanism.	Esteban JA, Soengas MS, Salas M, Blanco L	1994
A new DNA-dependent ATPase which stimulates yeast DNA polymerase I and has DNA-unwinding activity.	Sugino A, Ryu BH, Sugino T, Naumovski L, Friedberg EC	1986
Stimulation of the processivity of the DNA polymerase of bacteriophage T4 by the polymerase accessory proteins. The role of ATP hydrolysis.	Jarvis TC, Newport JW, von Hippel PH	1991
Persistence of deoxyribonucleic acid polymerase I and its 5'--3' exonuclease activity in PolA mutants of Escherichia coli K12.	Lehman IR, Chien JR	1973
Crystal structure of epstein-barr virus DNA polymerase processivity factor BMRF1.	Murayama K, Nakayama S, Kato-Murayama M, Akasaka R, Ohbayashi N, Kamewari-Hayami Y, Terada T, Shirouzu M, Tsurumi T, Yokoyama S	2009
The mechanism of Escherichia coli deoxyribonucleic acid polymerase I. Magnetic resonance and kinetic studies of the role of metals.	Slater JP, Tamir I, Loeb LA, Mildvan AS	1972
Purification and characterization of bacteriophage N4-induced DNA polymerase.	Lindberg GK, Rist JK, Kunkel TA, Sugino A, Rothman-Denes LB	1988
Mouse DNA polymerase alpha. Subunit structure and identification of a species with associated exonuclease.	Chen YC, Bohn EW, Planck SR, Wilson SH	1979
The effect of template secondary structure on vaccinia DNA polymerase.	Challberg MD, Englund PT	1979
DNA polymerase-alpha. Purification and structural characterization of the near homogeneous enzyme from human KB cells.	Fisher PA, Korn D	1977
Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch.	Voehler MW, Eoff RL, McDonald WH, Guengerich FP, Stone MP	2009
GINS is a DNA polymerase epsilon accessory factor during chromosomal DNA replication in budding yeast.	Seki T, Akita M, Kamimura Y, Muramatsu S, Araki H, Sugino A	2006
Initiation of new DNA strands by the herpes simplex virus-1 primase-helicase complex and either herpes DNA polymerase or human DNA polymerase alpha.	Cavanaugh NA, Kuchta RD	2009
Purification and characterization of a DNA polymerase beta from Drosophila*.	Sakaguchi K, Boyd JB	1985
A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast.	Ricke RM, Bielinsky AK	2006
Kinetic evidence for inefficient and error-prone bypass across bulky N2-guanine DNA adducts by human DNA polymerase iota.	Choi JY, Guengerich FP	2006
The highly processive DNA polymerase of bacteriophage T5. Role of the unique N and C termini.	Andraos N, Tabor S, Richardson CC	2004
Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: I. Two distinct activities for individual ATP sites in the gamma complex.	Williams CR, Snyder AK, Kuzmic P, O'Donnell ME, Bloom LB	2004
DNA polymerase III holoenzyme of Escherichia coli. Purification and resolution into subunits.	McHenry C, Kornberg A	1977
Subunit interaction and regulation of activity through terminal domains of the family D DNA polymerase from Pyrococcus horikoshii.	Shen Y, Tang XF, Matsui I	2003
Role of DNA polymerase eta in the UV mutation spectrum in human cells.	Stary A, Kannouche PL, Lehmann AR, Sarasin A	2003
Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen.	Liu L, Rodriguez-Belmonte EM, Mazloum N, Xie B, Lee MY	2003
Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp.	Ason B, Handayani R, Williams CR, Bertram JG, Hingorani MM, O'Donnell ME, Goodman MF, Bloom LB	2003
Weak strand displacement activity enables human DNA polymerase beta to expand CAG/CTG triplet repeats at strand breaks.	Hartenstine MJ, Goodman MF, Petruska J	2002
Contacts between the 5' nuclease of DNA polymerase I and its DNA substrate.	Xu Y, Potapova O, Leschziner AE, Grindley ND, Joyce CM	2001
A three-domain structure for the delta subunit of the DNA polymerase III holoenzyme delta domain III binds delta' and assembles into the DnaX complex.	Bullard JM, Pritchard AE, Song MS, Glover BP, Wieczorek A, Chen J, Janjic N, McHenry CS	2002
Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone.	DeMott MS, Beyret E, Wong D, Bales BC, Hwang JT, Greenberg MM, Demple B	2002
Resolving a fidelity paradox: why Escherichia coli DNA polymerase II makes more base substitution errors in AT- compared with GC-rich DNA.	Wang Z, Lazarov E, O'Donnell ME, Goodman MF	2002
Chromodomain protein Swi6-mediated role of DNA polymerase alpha in establishment of silencing in fission Yeast.	Ahmed S, Saini S, Arora S, Singh J	2001
Mismatch extension ability of yeast and human DNA polymerase eta.	Washington MT, Johnson RE, Prakash S, Prakash L	2001
Secondary structure and structure-activity relationships of peptides corresponding to the subunit interface of herpes simplex virus DNA polymerase.	Bridges KG, Hua Q, Brigham-Burke MR, Martin JD, Hensley P, Dahl CE, Digard P, Weiss MA, Coen DM	2000
The E249K mutator mutant of DNA polymerase beta extends mispaired termini.	Kosa JL, Sweasy JB	1999
Isolation and characterization of a split B-type DNA polymerase from the archaeon Methanobacterium thermoautotrophicum deltaH.	Kelman Z, Pietrokovski S, Hurwitz J	1999
Mismatch extension by Escherichia coli DNA polymerase III holoenzyme.	Pham PT, Olson MW, McHenry CS, Schaaper RM	1999
Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanism.	Prasad R, Beard WA, Strauss PR, Wilson SH	1998
Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, molecular analysis, and association in the native enzyme.	Wang Y, Farr CL, Kaguni LS	1997
Pre-steady state analysis of the assembly of wild type and mutant circular clamps of Escherichia coli DNA polymerase III onto DNA.	Bertram JG, Bloom LB, Turner J, O'Donnell ME, Beechem JM, Goodman MF	1998
The Escherichia coli polB locus is identical to dinA, the structural gene for DNA polymerase II. Characterization of Pol II purified from a polB mutant.	Qiu Z, Goodman MF	1997
Mutational studies of human DNA polymerase alpha. Serine 867 in the second most conserved region among alpha-like DNA polymerases is involved in primer binding and mispair primer extension.	Dong Q, Copeland WC, Wang TS	1993
DNA polymerase alpha overcomes an error-prone pause site in the presence of replication protein-A.	Suzuki M, Izuta S, Yoshida S	1994
Adenovirus DNA polymerase is a phosphoprotein.	Ramachandra M, Nakano R, Mohan PM, Rawitch AB, Padmanabhan R	1993
Evidence that an archaeal alpha-like DNA polymerase has a modular organization of its associated catalytic activities.	Pisani FM, Rossi M	1994
Interaction of proliferating cell nuclear antigen with yeast DNA polymerase delta.	Brown WC, Campbell JL	1993
Structural relationships between two forms of DNA polymerase epsilon from calf thymus.	Siegal G, Turchi JJ, Jessee CB, Mallaber LM, Bambara RA, Myers TW	1992
Immunoaffinity-purified DNA polymerase alpha from a mouse temperature-sensitive mutant, tsFT20 strain, is heat-labile.	Takada-Takayama R, Hanaoka F, Yamada M, Ui M	1991
DNA polymerase lambda mediates a back-up base excision repair activity in extracts of mouse embryonic fibroblasts.	Braithwaite EK, Prasad R, Shock DD, Hou EW, Beard WA, Wilson SH	2005
The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1.	Maga G, van Loon B, Crespan E, Villani G, Hübscher U	2009
Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI G3 site.	Choi JY, Stover JS, Angel KC, Chowdhury G, Rizzo CJ, Guengerich FP	2006
Site-directed mutations of T4 helicase loading protein (gp59) reveal multiple modes of DNA polymerase inhibition and the mechanism of unlocking by gp41 helicase.	Nelson SW, Yang J, Benkovic SJ	2006
Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cells.	Yang IY, Miller H, Wang Z, Frank EG, Ohmori H, Hanaoka F, Moriya M	2003
Threonine 79 is a hinge residue that governs the fidelity of DNA polymerase beta by helping to position the DNA within the active site.	Maitra M, Gudzelak A, Li SX, Matsumoto Y, Eckert KA, Jager J, Sweasy JB	2002
DNA polymerase lambda from calf thymus preferentially replicates damaged DNA.	Ramadan K, Shevelev IV, Maga G, Hübscher U	2002
Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts.	Chiapperino D, Kroth H, Kramarczuk IH, Sayer JM, Masutani C, Hanaoka F, Jerina DM, Cheh AM	2002
Fidelity and damage bypass ability of Schizosaccharomyces pombe Eso1 protein, comprised of DNA polymerase eta and sister chromatid cohesion protein Ctf7.	Madril AC, Johnson RE, Washington MT, Prakash L, Prakash S	2001
Carboxyl-terminal domain III of the delta' subunit of the DNA polymerase III holoenzyme binds delta.	Song MS, Dallmann HG, McHenry CS	2001
Multiple phosphorylation sites of DNA polymerase alpha-primase cooperate to regulate the initiation of DNA replication in vitro.	Schub O, Rohaly G, Smith RW, Schneider A, Dehde S, Dornreiter I, Nasheuer HP	2001
Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair.	García-Díaz M, Bebenek K, Kunkel TA, Blanco L	2001
Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1.	Li B, Lee MY	2001
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma.	Lim SE, Copeland WC	2001
A complex of the bacteriophage T7 primase-helicase and DNA polymerase directs primer utilization.	Kato M, Frick DN, Lee J, Tabor S, Richardson CC, Ellenberger T	2001
Lesion bypass by the Escherichia coli DNA polymerase V requires assembly of a RecA nucleoprotein filament.	Reuven NB, Arad G, Stasiak AZ, Stasiak A, Livneh Z	2001
FEN1 stimulation of DNA polymerase beta mediates an excision step in mammalian long patch base excision repair.	Prasad R, Dianov GL, Bohr VA, Wilson SH	2000
3'-Azido-3'-deoxythymidine-resistant mutants of DNA polymerase beta identified by in vivo selection.	Kosa JL, Sweasy JB	1999
Strand asymmetry of +1 frameshift mutagenesis at a homopolymeric run by DNA polymerase III holoenzyme of Escherichia coli.	Seki M, Akiyama MT, Sugaya Y, Ohtsubo E, Maki H	1999
Analysis of strand slippage in DNA polymerase expansions of CAG/CTG triplet repeats associated with neurodegenerative disease.	Petruska J, Hartenstine MJ, Goodman MF	1998
Architecture of the active DNA polymerase delta.proliferating cell nuclear antigen.template-primer complex.	Mozzherin DJ, Tan CK, Downey KM, Fisher PA	1999
Role of the putative zinc finger domain of Saccharomyces cerevisiae DNA polymerase epsilon in DNA replication and the S/M checkpoint pathway.	Dua R, Levy DL, Campbell JL	1998
A smaller form of the sliding clamp subunit of DNA polymerase III is induced by UV irradiation in Escherichia coli.	Skaliter R, Paz-Elizur T, Livneh Z	1996
Characterization of the p125 subunit of human DNA polymerase delta and its deletion mutants. Interaction with cyclin-dependent kinase-cyclins.	Wu SM, Zhang P, Zeng XR, Zhang SJ, Mo J, Li BQ, Lee MY	1998
Structural analyses of gp45 sliding clamp interactions during assembly of the bacteriophage T4 DNA polymerase holoenzyme. I. Conformational changes within the gp44/62-gp45-ATP complex during clamp loading.	Pietroni P, Young MC, Latham GJ, von Hippel PH	1997
Dissociation of the protein primer and DNA polymerase after initiation of adenovirus DNA replication.	King AJ, Teertstra WR, van der Vliet PC	1997
Effects of Xenopus laevis mitochondrial single-stranded DNA-binding protein on primer-template binding and 3'-->5' exonuclease activity of DNA polymerase gamma.	Mikhailov VS, Bogenhagen DF	1996
Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts.	Efrati E, Tocco G, Eritja R, Wilson SH, Goodman MF	1997
Pyridoxal 5'-phosphate inhibition of adenovirus DNA polymerase.	Monaghan A, Hay RT	1996
DNA replication-related elements cooperate to enhance promoter activity of the drosophila DNA polymerase alpha 73-kDa subunit gene.	Takahashi Y, Yamaguchi M, Hirose F, Cotterill S, Kobayashi J, Miyajima S, Matsukage A	1996
Phorbol ester abrogates up-regulation of DNA polymerase beta by DNA-alkylating agents in Chinese hamster ovary cells.	Srivastava DK, Rawson TY, Showalter SD, Wilson SH	1995
Structural and functional organization of herpes simplex virus DNA polymerase investigated by limited proteolysis.	Weisshart K, Kuo AA, Hwang CB, Kumura K, Coen DM	1994
Identification of residues in the single-stranded DNA-binding site of the 8-kDa domain of rat DNA polymerase beta by UV cross-linking.	Prasad R, Kumar A, Widen SG, Casas-Finet JR, Wilson SH	1993
Mutational analysis of the human DNA polymerase alpha. The most conserved region in alpha-like DNA polymerases is involved in metal-specific catalysis.	Copeland WC, Wang TS	1993
Poly(ADP-ribose) polymerase stimulates DNA polymerase alpha by physical association.	Simbulan CM, Suzuki M, Izuta S, Sakurai T, Savoysky E, Kojima K, Miyahara K, Shizuta Y, Yoshida S	1993
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Purification of a mitochondrial DNA polymerase from Crithidia fasciculata.	Torri AF, Englund PT	1992
Constitution of the twin polymerase of DNA polymerase III holoenzyme.	Studwell-Vaughan PS, O'Donnell ME	1991
Modular organization of T4 DNA polymerase. Evidence from phylogenetics.	Wang CC, Yeh LS, Karam JD	1995
A single mutation in human mitochondrial DNA polymerase Pol gammaA affects both polymerization and proofreading activities of only the holoenzyme.	Lee YS, Johnson KA, Molineux IJ, Yin YW	2010
Dehydroaltenusin, a mammalian DNA polymerase alpha inhibitor.	Mizushina Y, Kamisuki S, Mizuno T, Takemura M, Asahara H, Linn S, Yamaguchi T, Matsukage A, Hanaoka F, Yoshida S, Saneyoshi M, Sugawara F, Sakaguchi K	2000
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The linker region between the helicase and primase domains of the bacteriophage T7 gene 4 protein is critical for hexamer formation.	Guo S, Tabor S, Richardson CC	1999
Formation of a DNA loop at the replication fork generated by bacteriophage T7 replication proteins.	Park K, Debyser Z, Tabor S, Richardson CC, Griffith JD	1998
Sequence requirements for protein-primed initiation and elongation of phage O29 DNA replication.	Gonzalez-Huici V, Salas M, Hermoso JM	2000
Truncating alpha-helix E' of p66 human immunodeficiency virus reverse transcriptase modulates RNase H function and impairs DNA strand transfer.	Ghosh M, Howard KJ, Cameron CE, Benkovic SJ, Hughes SH, Le Grice SF	1995
Characterization of the helicase and primase activities of the 63-kDa component of the bacteriophage T7 gene 4 protein.	Bernstein JA, Richardson CC	1989
Human immunodeficiency virus reverse transcriptase. Functional mutants obtained by random mutagenesis coupled with genetic selection in Escherichia coli.	Kim B, Hathaway TR, Loeb LA	1996
Effects of aphidicolin and/or 2',3'-dideoxythymidine on DNA repair induced in HeLa cells by four types of DNA-damaging agents.	Yamada K, Hanaoka F, Yamada M	1985
Leading and lagging strand synthesis at the replication fork of bacteriophage T7. Distinct properties of T7 gene 4 protein as a helicase and primase.	Nakai H, Richardson CC	1988
Priming of deoxyribonucleic acid synthesis on phage fd and phiX174 templates by oligoribonucleotides contaminating nucleoside 5'-triphosphates.	Masamune Y, Richardson CC	1977
Tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain III, shared by gamma and tau, binds delta delta ' and chi psi.	Gao D, McHenry CS	2001
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Incorporation and replication of 8-oxo-deoxyguanosine by the human mitochondrial DNA polymerase.	Hanes JW, Thal DM, Johnson KA	2006
Characterization of novel reverse transcriptase and other RNA-associated catalytic activities by human DNA polymerase gamma: importance in mitochondrial DNA replication.	Murakami E, Feng JY, Lee HR, Hanes J, Johnson KA, Anderson KS	2003
Role of induced fit in enzyme specificity: a molecular forward/reverse switch.	Johnson KA	2008
Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase.	Fowler JD, Brown JA, Johnson KA, Suo Z	2008
Role of histidine 932 of the human mitochondrial DNA polymerase in nucleotide discrimination and inherited disease.	Batabyal D, McKenzie JL, Johnson KA	2010
Fidelity of the human mitochondrial DNA polymerase.	Lee HR, Johnson KA	2006
Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs.	Feng JY, Johnson AA, Johnson KA, Anderson KS	2001
Fidelity and processivity of reverse transcription by the human mitochondrial DNA polymerase.	Lee HR, Johnson KA	2007
Each monomer of the dimeric accessory protein for human mitochondrial DNA polymerase has a distinct role in conferring processivity.	Lee YS, Lee S, Demeler B, Molineux IJ, Johnson KA, Yin YW	2010
Base pair hydrogen bonds are essential for proofreading selectivity by the human mitochondrial DNA polymerase.	Lee HR, Helquist SA, Kool ET, Johnson KA	2008
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Exonuclease proofreading by human mitochondrial DNA polymerase.	Johnson AA, Johnson KA	2001
DNA secondary structure effects on DNA synthesis catalyzed by HIV-1 reverse transcriptase.	Suo Z, Johnson KA	1998
Identification of a new motif required for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): the RRRY motif is necessary for the binding of single-stranded DNA substrate and the template strand of the mismatched duplex.	Kukreti P, Singh K, Ketkar A, Modak MJ	2008
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Distinct complexes of DNA polymerase I (Klenow fragment) for base and sugar discrimination during nucleotide substrate selection.	Garalde DR, Simon CA, Dahl JM, Wang H, Akeson M, Lieberman KR	2011
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Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect.	Gao L, Hanson MN, Balakrishnan M, Boyer PL, Roques BP, Hughes SH, Kim B, Bambara RA	2008
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Psychotrine and its O-methyl ether are selective inhibitors of human immunodeficiency virus-1 reverse transcriptase.	Tan GT, Kinghorn AD, Hughes SH, Pezzuto JM	1991
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Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers.	Kasiviswanathan R, Gustafson MA, Copeland WC, Meyer JN	2011
Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase δ.	Xu LH, Huang M, Fang SG, Liu DX	2011
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The emergence of different resistance mechanisms toward nucleoside inhibitors is explained by the properties of the wild type HIV-1 reverse transcriptase.	Isel C, Ehresmann C, Walter P, Ehresmann B, Marquet R	2001
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An alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicase.	Pike JasonE, Henry RyanA, Burgers PeterMJ, Campbell JudithL, Bambara RobertA	2010
Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway.	Pike JasonE, Burgers PeterMJ, Campbell JudithL, Bambara RobertA	2009
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The stereoselective targeting of a specific enzyme-substrate complex is the molecular mechanism for the synergic inhibition of HIV-1 reverse transcriptase by (R)-(-)-PPO464: a novel generation of nonnucleoside inhibitors.	Maga G, Ramunno A, Nacci V, Locatelli GA, Spadari S, Fiorini I, Baldanti F, Paolucci S, Zavattoni M, Bergamini A, Galletti B, Muck S, Hubscher U, Giorgi G, Guiso G, Caccia S, Campiani G	2001
Primer unblocking and rescue of DNA synthesis by azidothymidine (AZT)-resistant HIV-1 reverse transcriptase: comparison between initiation and elongation of reverse transcription and between (-) and (+) strand DNA synthesis.	Rigourd M, Ehresmann C, Parniak MA, Ehresmann B, Marquet R	2002
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Structural and mutational studies of a hyperthermophilic intein from DNA polymerase II of Pyrococcus abyssi.	Du Z, Liu J, Albracht CD, Hsu A, Chen W, Marieni MD, Colelli KM, Williams JE, Reitter JN, Mills KV, Wang C	2011
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N348I in HIV-1 reverse transcriptase can counteract the nevirapine-mediated bias toward RNase H cleavage during plus-strand initiation.	Biondi MJ, Beilhartz GL, McCormick S, Götte M	2010
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Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis.	Ponamarev MV, Longley MJ, Nguyen D, Kunkel TA, Copeland WC	2002
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Evaluation of the role of the vaccinia virus uracil DNA glycosylase and A20 proteins as intrinsic components of the DNA polymerase holoenzyme.	Boyle KA, Stanitsa ES, Greseth MD, Lindgren JK, Traktman P	2011
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Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins.	Matsumoto Y, Kim K, Hurwitz J, Gary R, Levin DS, Tomkinson AE, Park MS	1999
Replication of bovine papillomavirus type 1 origin-containing DNA in crude extracts and with purified proteins.	Müller F, Seo YS, Hurwitz J	1994
A DNA lesion alters the global conformational dynamics of a Y-Family DNA polymerase during catalysis.	Maxwell BA, Xu C, Suo Z	2012
The replication of DNA containing the simian virus 40 origin by the monopolymerase and dipolymerase systems.	Eki T, Matsumoto T, Murakami Y, Hurwitz J	1992
Influence of poly(ADP-ribose) polymerase on the enzymatic synthesis of SV40 DNA.	Eki T, Hurwitz J	1991
Complete enzymatic synthesis of DNA containing the SV40 origin of replication.	Ishimi Y, Claude A, Bullock P, Hurwitz J	1988
Protein-primed replication of plasmids containing the terminus of the adenovirus genome. II. Purification and characterization of a host protein required for the replication of DNA templates devoid of the terminal protein.	Guggenheimer RA, Nagata K, Kenny M, Hurwitz J	1984
Role of polymeric forms of the bacteriophage phi X174 coded gene A protein in phi XRFI DNA cleavage.	Ikeda JE, Yudelevich A, Shimamoto N, Hurwitz J	1979
In Vitro Gap-directed Translesion DNA Synthesis of an Abasic Site Involving Human DNA Polymerases {epsilon}, {lambda}, and {beta}.	Villani G, Hubscher U, Gironis N, Parkkinen S, Pospiech H, Shevelev IV, di Cicco G, Markkanen E, Syväoja JE, Tanguy Le Gac N	2011
Uracil-DNA glycosylase inhibitor gene of bacteriophage PBS2 encodes a binding protein specific for uracil-DNA glycosylase.	Wang Z, Mosbaugh DW	1989
Nevirapine resistance mutation at codon 181 of the HIV-1 reverse transcriptase confers stavudine resistance by increasing nucleotide substrate discrimination and phosphorolytic activity.	Blanca G, Baldanti F, Paolucci S, Skoblov AY, Victorova L, Hübscher U, Gerna G, Spadari S, Maga G	2003
Design of structure-based reverse transcriptase inhibitors.	Kang I, Wang JH	1994
Role of the "helix clamp" in HIV-1 reverse transcriptase catalytic cycling as revealed by alanine-scanning mutagenesis.	Beard WA, Minnick DT, Wade CL, Prasad R, Won RL, Kumar A, Kunkel TA, Wilson SH	1996
Active site mapping of the catalytic mouse primase subunit by alanine scanning mutagenesis.	Copeland WC, Tan X	1995
Mechanism of HIV-1 reverse transcriptase. Termination of processive synthesis on a natural DNA template is influenced by the sequence of the template-primer stem.	Abbotts J, Bebenek K, Kunkel TA, Wilson SH	1993
Thermodynamics of A:G mismatch poly(dG) synthesis by human immunodeficiency virus 1 reverse transcriptase.	Abbotts J, Jaju M, Wilson SH	1991
Synthesis of DNA by human immunodeficiency virus reverse transcriptase is preferentially blocked at template oligo(deoxyadenosine) tracts.	Williams KJ, Loeb LA, Fry M	1990
Kinetics of deoxyribonucleotide insertion and extension at abasic template lesions in different sequence contexts using HIV-1 reverse transcriptase.	Cai H, Bloom LB, Eritja R, Goodman MF	1993
Processing of the primer for plus strand DNA synthesis by human immunodeficiency virus 1 reverse transcriptase.	Huber HE, Richardson CC	1990
Identification and characterization of an intermediate in the alkali degradation of (6-4) photoproduct-containing DNA.	Higurashi M, Ohtsuki T, Inase A, Kusumoto R, Masutani C, Hanaoka F, Iwai S	2003
Raloxifene increases proliferation and up-regulates telomerase activity in human umbilical vein endothelial cells.	Doshida M, Ohmichi M, Tsutsumi S, Kawagoe J, Takahashi T, Du B, Mori-Abe A, Ohta T, Saitoh-Sekiguchi M, Takahashi K, Kurachi H	2006
A novel interaction of tRNA(Lys,3) with the feline immunodeficiency virus RNA genome governs initiation of minus strand DNA synthesis.	Miller JT, Ehresmann B, Hübscher U, Le Grice SF	2001
A direct interaction between proliferating cell nuclear antigen (PCNA) and Cdk2 targets PCNA-interacting proteins for phosphorylation.	Koundrioukoff S, Jónsson ZO, Hasan S, de Jong RN, van der Vliet PC, Hottiger MO, Hübscher U	2000
Calf thymus Hsc70 protein protects and reactivates prokaryotic and eukaryotic enzymes.	Ziemienowicz A, Zylicz M, Floth C, Hübscher U	1995
A mammalian protein complex that repairs double-strand breaks and deletions by recombination.	Jessberger R, Podust V, Hübscher U, Berg P	1993
Stimulation of NEIL2-mediated oxidized base excision repair via YB-1 interaction during oxidative stress.	Das S, Chattopadhyay R, Bhakat KK, Boldogh I, Kohno K, Prasad R, Wilson SH, Hazra TK	2007
Molecular insights into DNA polymerase deterrents for ribonucleotide insertion.	Cavanaugh NA, Beard WA, Batra VK, Perera L, Pedersen LG, Wilson SH	2011
Substrate channeling in mammalian base excision repair pathways: passing the baton.	Prasad R, Shock DD, Beard WA, Wilson SH	2010
Functional interactions between SV40 T antigen and other replication proteins at the replication fork.	Murakami Y, Hurwitz J	1993
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes.	Masuda K, Ouchida R, Hikida M, Kurosaki T, Yokoi M, Masutani C, Seki M, Wood RD, Hanaoka F, O-Wang J	2007
Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure.	Horton JK, Stefanick DF, Naron JM, Kedar PS, Wilson SH	2005
Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses.	Sobol RW, Kartalou M, Almeida KH, Joyce DF, Engelward BP, Horton JK, Prasad R, Samson LD, Wilson SH	2003
Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair.	Lavrik OI, Prasad R, Sobol RW, Horton JK, Ackerman EJ, Wilson SH	2001
DNA primase-DNA polymerase alpha assembly from mouse FM3A cells. Purification of constituting enzymes, reconstitution, and analysis of RNA priming as coupled to DNA synthesis.	Suzuki M, Enomoto T, Masutani C, Hanaoka F, Yamada M, Ui M	1989
Minor groove interactions at the DNA polymerase beta active site modulate single-base deletion error rates.	Osheroff WP, Beard WA, Yin S, Wilson SH, Kunkel TA	2000
Differential regulation of the catalytic and accessory subunit genes of Drosophila mitochondrial DNA polymerase.	Lefai E, Fernandez-Moreno MA, Alahari A, Kaguni LS, Garesse R	2000
Mutagenic and nonmutagenic bypass of DNA lesions by Drosophila DNA polymerases dpoleta and dpoliota.	Ishikawa T, Uematsu N, Mizukoshi T, Iwai S, Iwasaki H, Masutani C, Hanaoka F, Ueda R, Ohmori H, Todo T	2001
Protection against methylation-induced cytotoxicity by DNA polymerase beta-dependent long patch base excision repair.	Horton JK, Prasad R, Hou E, Wilson SH	2000
Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps.	Srivastava DK, Berg BJ, Prasad R, Molina JT, Beard WA, Tomkinson AE, Wilson SH	1998
DNA primase stimulatory factor from mouse FM3A cells has an RNase H activity. Purification of the factor and analysis of the stimulation.	Masutani C, Enomoto T, Suzuki M, Hanaoka F, Ui M	1990
Isolation of temperature-sensitive cell cycle mutants from mouse FM3A cells. Characterization of mutants with special reference to DNA replication.	Eki T, Enomoto T, Miyajima A, Miyazawa H, Murakami Y, Hanaoka F, Yamada M, Ui M	1990
Activation of the human DNA polymerase beta promoter by a DNA-alkylating agent through induced phosphorylation of cAMP response element-binding protein-1.	Narayan S, He F, Wilson SH	1996
DNA polymerases alpha and beta are required for DNA repair in an efficient nuclear extract from Xenopus oocytes.	Oda N, Saxena JK, Jenkins TM, Prasad R, Wilson SH, Ackerman EJ	1996
Pyrovanadolysis, a Pyrophosphorolysis-like Reaction Mediated by Pyrovanadate, Mn2+, and DNA Polymerase of Bacteriophage T7.	Akabayov B, Kulczyk AW, Akabayov SR, Theile C, McLaughlin LW, Beauchamp B, van Oijen AM, Richardson CC	2011
Human beta-polymerase gene. Structure of the 5'-flanking region and active promoter.	Widen SG, Kedar P, Wilson SH	1988
Studies on the mechanism of human immunodeficiency virus reverse transcriptase. Steady-state kinetics, processivity, and polynucleotide inhibition.	Majumdar C, Abbotts J, Broder S, Wilson SH	1988
An in trans interaction at the interface of the helicase and primase domains of the hexameric gene 4 protein of bacteriophage T7 modulates their activities.	Zhu B, Lee SJ, Richardson CC	2009
Studies on catalytic subunits of mouse myeloma alpha-polymerase.	Karawya EM, Wilson SH	1982
Essential residues in the C terminus of the bacteriophage T7 gene 2.5 single-stranded DNA-binding protein.	Marintcheva B, Hamdan SM, Lee SJ, Richardson CC	2006
Acidic residues in the nucleotide-binding site of the bacteriophage T7 DNA primase.	Lee SJ, Richardson CC	2005
A single-stranded DNA-binding protein of bacteriophage T7 defective in DNA annealing.	Rezende LF, Willcox S, Griffith JD, Richardson CC	2003
The DNA binding domain of the gene 2.5 single-stranded DNA-binding protein of bacteriophage T7.	Hyland EM, Rezende LF, Richardson CC	2003
Essential amino acid residues in the single-stranded DNA-binding protein of bacteriophage T7. Identification of the dimer interface.	Rezende LF, Hollis T, Ellenberger T, Richardson CC	2002
Essential lysine residues in the RNA polymerase domain of the gene 4 primase-helicase of bacteriophage T7.	Lee SJ, Richardson CC	2001
The motif D loop of human immunodeficiency virus type 1 reverse transcriptase is critical for nucleoside 5'-triphosphate selectivity.	Canard B, Chowdhury K, Sarfati R, Doublié S, Richardson CC	1999
The effects of dNTP pool imbalances on frameshift fidelity during DNA replication.	Bebenek K, Roberts JD, Kunkel TA	1992
Heteroduplex repair in extracts of human HeLa cells.	Thomas DC, Roberts JD, Kunkel TA	1991
Kinetic analysis of base substitution mutagenesis by transient misalignment of DNA and by miscoding.	Boosalis MS, Mosbaugh DW, Hamatake R, Sugino A, Kunkel TA, Goodman MF	1989
Frameshift mutagenesis by eucaryotic DNA polymerases in vitro.	Kunkel TA	1986
Role of the acidic carboxyl-terminal domain of the single-stranded DNA-binding protein of bacteriophage T7 in specific protein-protein interactions.	Kong D, Richardson CC	1998
Gene 4 DNA primase of bacteriophage T7 mediates the annealing and extension of ribo-oligonucleotides at primase recognition sites.	Kusakabe T, Richardson CC	1997
Acidic carboxyl-terminal domain of gene 2.5 protein of bacteriophage T7 is essential for protein-protein interactions.	Kim YT, Richardson CC	1994
Mechanism of stimulation of DNA replication by bacteriophage phi 29 single-stranded DNA-binding protein p5.	Gutiérrez C, Martín G, Sogo JM, Salas M	1991
Ionization of bromouracil and fluorouracil stimulates base mispairing frequencies with guanine.	Yu H, Eritja R, Bloom LB, Goodman MF	1993
DNA binding properties of the deoxyguanosine triphosphate triphosphohydrolase of Escherichia coli.	Wurgler SM, Richardson CC	1993
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions.	Cheng KC, Cahill DS, Kasai H, Nishimura S, Loeb LA	1992
The effect of the T7 and Escherichia coli DNA-binding proteins at the replication fork of bacteriophage T7.	Nakai H, Richardson CC	1988
Processing of concatemers of bacteriophage T7 DNA in vitro.	White JH, Richardson CC	1987
Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins. Initiation of bidirectional synthesis.	Fuller CW, Richardson CC	1985
Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins. Site and direction of initial DNA synthesis.	Fuller CW, Richardson CC	1985
On the fidelity of DNA replication. Studies with human placenta DNA polymerases.	Seal G, Shearman CW, Loeb LA	1979
The gene 4 protein of bacteriophage T7. Characterization of helicase activity.	Matson SW, Tabor S, Richardson CC	1983
DNA-dependent nucleoside 5'-triphosphatase activity of the gene 4 protein of bacteriophage T7.	Matson SW, Richardson CC	1983
On the fidelity of DNA replication. Enzyme activities associated with DNA polymerases from RNA tumor viruses.	Seal G, Loeb LA	1976
Conformation of deoxynucleoside triphosphate substrates on DNA polymerase I from Escherichia coli as determined by nuclear magnetic relaxation.	Sloan DL, Loeb LA, Mildvan AS	1975
Avian myeloblastosis virus DNA polymerase. Kinetic studies on the incorporation of noncomplementary nucleotides.	Battula N, Dube D, Loeb LA	1975
On the fidelity of DNA replication. Characterization of polynucleotides with errors in base-pairing synthesized by avian myeloblastosis virus deoxyribonucleic acid polymerase.	Battula N, Loeb LA	1975
Bacteriophage T7 DNA replication. Synthesis of lagging strands in a reconstituted system using purified proteins.	Engler MJ, Richardson CC	1983
Long patch base excision repair in mammalian mitochondrial genomes.	Szczesny B, Tann AW, Longley MJ, Copeland WC, Mitra S	2008
Bacteriophage T7 deoxyribonucleic acid replication in vitro. Purification and properties of the gene 4 protein of bacteriophage T7.	Hinkle DC, Richardson CC	1975
Deoxyribonucleic acid polymerase III of Escherichia coli. Purification and properties.	Livingston DM, Hinkle DC, Richardson CC	1975
Deoxyribonucleic acid polymerase III of Escherichia coli. Characterization of associated exonuclease activities.	Livingston DM, Richardson CC	1975
Discovery and characterization of the cryptic psi subunit of the pseudomonad DNA replicase.	Jarvis TC, Beaudry AA, Bullard JM, Ochsner U, Dallmann HG, McHenry CS	2005
Reconstitution of a minimal DNA replicase from Pseudomonas aeruginosa and stimulation by non-cognate auxiliary factors.	Jarvis TC, Beaudry AA, Bullard JM, Janjic N, McHenry CS	2005
tau binds and organizes Escherichia coli replication proteins through distinct domains: domain III, shared by gamma and tau, oligomerizes DnaX.	Glover BP, Pritchard AE, McHenry CS	2001
The beta subunit of the DNA polymerase III holoenzyme becomes inaccessible to antibody after formation of an initiation complex with primed DNA.	Johanson KO, McHenry CS	1982
tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain IV, located within the unique C terminus of tau, binds the replication fork, helicase, DnaB.	Gao D, McHenry CS	2001
tau binds and organizes Escherichia coli replication through distinct domains. Partial proteolysis of terminally tagged tau to determine candidate domains and to assign domain V as the alpha binding domain.	Gao D, McHenry CS	2001
Characterization of the unique C terminus of the Escherichia coli tau DnaX protein. Monomeric C-tau binds alpha AND DnaB and can partially replace tau in reconstituted replication forks.	Dallmann HG, Kim S, Pritchard AE, Marians KJ, McHenry CS	2000
tau couples the leading- and lagging-strand polymerases at the Escherichia coli DNA replication fork.	Kim S, Dallmann HG, McHenry CS, Marians KJ	1996
Identification of the beta-binding domain of the alpha subunit of Escherichia coli polymerase III holoenzyme.	Kim DR, McHenry CS	1996
Tau protects beta in the leading-strand polymerase complex at the replication fork.	Kim S, Dallmann HG, McHenry CS, Marians KJ	1996
Monoclonal antibodies specific for the tau subunit of the DNA polymerase III holoenzyme of Escherichia coli. Use to demonstrate that tau is the product of the dnaZX gene and that both it and gamma, the dnaZ gene product, are integral components of the same enzyme assembly.	Hawker JR, McHenry CS	1987
The beta subunit of the Escherichia coli DNA polymerase III holoenzyme interacts functionally with the catalytic core in the absence of other subunits.	LaDuca RJ, Crute JJ, McHenry CS, Bambara RA	1986
Structure of the DNA repair helicase hel308 reveals DNA binding and autoinhibitory domains.	Richards JD, Johnson KA, Liu H, McRobbie AM, McMahon S, Oke M, Carter L, Naismith JH, White MF	2008
Molecular mechanism and energetics of clamp assembly in Escherichia coli. The role of ATP hydrolysis when gamma complex loads beta on DNA.	Bertram JG, Bloom LB, Hingorani MM, Beechem JM, O'Donnell ME, Goodman MF	2000
Enthalpy-entropy compensation in DNA melting thermodynamics.	Petruska J, Goodman MF	1995
Ribonucleotide discrimination and reverse transcription by the human mitochondrial DNA polymerase.	Kasiviswanathan R, Copeland WC	2011
Base mispair extension kinetics. Binding of avian myeloblastosis reverse transcriptase to matched and mismatched base pair termini.	Creighton S, Huang MM, Cai H, Arnheim N, Goodman MF	1992
Nucleotide insertion kinetics opposite abasic lesions in DNA.	Randall SK, Eritja R, Kaplan BE, Petruska J, Goodman MF	1987
Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase.	Mendelman LV, Petruska J, Goodman MF	1990
Enzymatic characterization of the individual mammalian primase subunits reveals a biphasic mechanism for initiation of DNA replication.	Copeland WC, Wang TS	1993
Translesion synthesis past acrolein-derived DNA adduct, gamma -hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta.	Minko IG, Washington MT, Kanuri M, Prakash L, Prakash S, Lloyd RS	2003
UmuD(2) inhibits a non-covalent step during DinB-mediated template slippage on homopolymeric nucleotide runs.	Foti JJ, DeLucia AM, Joyce CM, Walker GC	2010
The properties of steric gate mutants reveal different constraints within the active sites of Y-family and A-family DNA polymerases.	DeLucia AM, Chaudhuri S, Potapova O, Grindley ND, Joyce CM	2006
An Interaction between DNA Polymerase and Helicase is Essential for the High Processivity of the Bacteriophage T7 Replisome.	Kulczyk AW, Akabayov B, Lee SJ, Bostina M, Berkowitz SA, Richardson CC	2012
Analyzing the handoff of DNA from UvrA to UvrB utilizing DNA-protein photoaffinity labeling.	DellaVecchia MJ, Croteau DL, Skorvaga M, Dezhurov SV, Lavrik OI, Van Houten B	2004
The positively charged surface of herpes simplex virus UL42 mediates DNA binding.	Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM	2008
Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1.	Choi JY, Guengerich FP	2008
The 44P subunit of the T4 DNA polymerase accessory protein complex catalyzes ATP hydrolysis.	Rush J, Lin TC, Quinones M, Spicer EK, Douglas I, Williams KR, Konigsberg WH	1989
Roles of the Four DNA Polymerases of the Crenarchaeon Sulfolobus solfataricus and Accessory Proteins in DNA Replication.	Choi JY, Eoff RL, Pence MG, Wang J, Martin MV, Kim EJ, Folkmann LM, Guengerich FP	2011
In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenic.	Hoffmann JS, Pillaire MJ, Garcia-Estefania D, Lapalu S, Villani G	1996
Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners.	Frouin I, Maga G, Denegri M, Riva F, Savio M, Spadari S, Prosperi E, Scovassi AI	2003
Conversion of monofunctional DNA adducts of cis-diamminedichloroplatinum (II) to bifunctional lesions. Effect on the in vitro replication of single-stranded DNA by Escherichia coli DNA polymerase I and eukaryotic DNA polymerases alpha.	Hoffmann JS, Johnson NP, Villani G	1989
Initiation of DNA replication by the dnaG protein.	Benz EW, Reinberg D, Vicuna R, Hurwitz J	1980
Fission yeast Mcm10p contains primase activity.	Fien K, Hurwitz J	2006
A complex consisting of human replication factor C p40, p37, and p36 subunits is a DNA-dependent ATPase and an intermediate in the assembly of the holoenzyme.	Cai J, Gibbs E, Uhlmann F, Phillips B, Yao N, O'Donnell ME, Hurwitz J	1997
Transcription-positive cofactor 4 forms complexes with HSSB (RPA) on single-stranded DNA and influences HSSB-dependent enzymatic synthesis of simian virus 40 DNA.	Pan ZQ, Ge H, Amin AA, Hurwitz J	1996
Studies on the role of the phi X174 gene A protein in phi X viral strand synthesis. II. Effects of DNA replication of mutations in the 30-nucleotide icosahedral bacteriophage origin.	Goetz GS, Schmidt-Glenewinkel T, Hu MH, Belgado N, Hurwitz J	1988
Studies on the role of the phi X174 gene A protein in phi X viral strand synthesis. I. Replication of DNA containing an alteration in position 1 of the 30-nucleotide icosahedral bacteriophage origin.	Goetz GS, Hurwitz J	1988
Initiation of adenovirus DNA replication. II. Structural requirements using synthetic oligonucleotide adenovirus templates.	Kenny MK, Hurwitz J	1988
Initiation of adenovirus DNA replication. I. Mechanism of action of a host protein required for replication of adenovirus DNA templates devoid of the terminal protein.	Kenny MK, Balogh LA, Hurwitz J	1988
Protein-primed replication of plasmids containing the terminus of the adenovirus genome. I. Characterization of an in vitro DNA replication system dependent on adenoviral DNA sequences.	Guggenheimer RA, Nagata K, Lindenbaum J, Hurwitz J	1984
Selective inhibition of phiX RFII compared with fd RFII DNA synthesis in vitro. II. Resolution of discrimination reaction into multiple steps.	Vicuna R, Ikeda JE, Hurwitz J	1977
Selective inhibition of in vitro DNA synthesis dependent on phiX174 compared with fd DNA. I. Protein requirements for selective inhibition.	Vicuna R, Hurwitz J, Wallace S, Girard M	1977
The archaeal DNA primase: biochemical characterization of the p41-p46 complex from Pyrococcus furiosus.	Liu L, Komori K, Ishino S, Bocquier AA, Cann IK, Kohda D, Ishino Y	2001
Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove.	Latham GJ, Forgacs E, Beard WA, Prasad R, Bebenek K, Kunkel TA, Wilson SH, Lloyd RS	2000
Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions.	Beard WA, Bebenek K, Darden TA, Li L, Prasad R, Kunkel TA, Wilson SH	1998
Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots.	Bebenek K, Abbotts J, Wilson SH, Kunkel TA	1993
Probing structure/function relationships of HIV-1 reverse transcriptase with styrene oxide N2-guanine adducts.	Forgacs E, Latham G, Beard WA, Prasad R, Bebenek K, Kunkel TA, Wilson SH, Lloyd RS	1997
Human immunodeficiency virus type 1 reverse transcriptase. 3'-Azidodeoxythymidine 5'-triphosphate inhibition indicates two-step binding for template-primer.	Jaju M, Beard WA, Wilson SH	1995
Specificity and mechanism of error-prone replication by human immunodeficiency virus-1 reverse transcriptase.	Bebenek K, Abbotts J, Roberts JD, Wilson SH, Kunkel TA	1989
Human immunodeficiency virus reverse transcriptase. Expression in Escherichia coli, purification, and characterization of a functionally and structurally asymmetric dimeric polymerase.	Thimmig RL, McHenry CS	1993
Analysis of the effect of bulk at N2-alkylguanine DNA adducts on catalytic efficiency and fidelity of the processive DNA polymerases bacteriophage T7 exonuclease- and HIV-1 reverse transcriptase.	Choi JY, Guengerich FP	2004
Human telomerase reverse transcriptase immortalizes bovine lens epithelial cells and suppresses differentiation through regulation of the ERK signaling pathway.	Wang J, Feng H, Huang XQ, Xiang H, Mao YW, Liu JP, Yan Q, Liu WB, Liu Y, Deng M, Gong L, Sun S, Luo C, Liu SJ, Zhang XJ, Liu Y, Li DW	2005
Characterization of the elongation complex of dengue virus RNA polymerase: assembly, kinetics of nucleotide incorporation, and fidelity.	Jin Z, Deval J, Johnson KA, Swinney DC	2011
DNA ligase I selectively affects DNA synthesis by DNA polymerases delta and epsilon suggesting differential functions in DNA replication and repair.	Mossi R, Ferrari E, Hübscher U	1998
Strand displacement activity of the human immunodeficiency virus type 1 reverse transcriptase heterodimer and its individual subunits.	Hottiger M, Podust VN, Thimmig RL, McHenry C, Hübscher U	1994
DNA helicase from calf thymus. Purification to apparent homogeneity and biochemical characterization of the enzyme.	Thömmes P, Hübscher U	1990
The Human POLB Gene is Mutated in a High Percentage of Colorectal Tumors.	Donigan KA, Sun KW, Nemec AA, Murphy DL, Cong X, Northrup V, Zelterman D, Sweasy JB	2012
Interferon regulatory factor 1 transactivates expression of human DNA polymerase η in response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidine.	Qi H, Zhu H, Lou M, Fan Y, Liu H, Shen J, Li Z, Lv X, Shan J, Zhu L, Chin YE, Shao J	2012
Direct observation of translocation in individual DNA polymerase complexes.	Dahl JM, Mai AH, Cherf GM, Jetha NN, Garalde DR, Marziali A, Akeson M, Wang H, Lieberman KR	2012
HIV-1 reverse transcriptase (RT) polymorphism 172K, suppresses the effect of clinically relevant drug resistance mutations to both nucleoside and nonnucleoside RT inhibitors.	Hachiya A, Marchand B, Kirby KA, Michailidis E, Tu X, Palczewski K, Ong YT, Li Z, Griffin DT, Schuckmann MM, Tanuma J, Oka S, Singh K, Kodama EN, Sarafianos SG	2012
Amino acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase.	Obeid S, Welte W, Diederichs K, Marx A	2012
DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ.	Baranovskiy AG, Lada AG, Siebler HM, Zhang Y, Pavlov YI, Tahirov TH	2012
Biochemical Mechanism of HIV-1 Resistance to Rilpivirine.	Singh K, Marchand B, Rai DK, Sharma B, Michailidis E, Ryan EM, Matzek KB, Leslie MD, Hagedorn AN, Li Z, Norden PR, Hachiya A, Parniak MA, Xu HT, Wainberg MA, Sarafianos SG	2012
Thioredoxin, the Processivity Factor, Sequesters an Exposed Cysteine in the Thumb Domain of Bacteriophage T7 DNA Polymerase.	Tran NQ, Lee SJ, Akabayov B, Johnson DE, Richardson CC	2012
Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase α-primase.	Zhou B, Arnett DR, Yu X, Brewster A, Sowd GA, Xie CL, Vila S, Gai D, Fanning E, Chen XS	2012
Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.	Wang W, Wu EY, Hellinga HW, Beese LS	2012
My life with bacteriophage O29.	Salas M	2012
Human DNA Polymerase {epsilon} Is Able to Efficiently Extend from Multiple Consecutive Ribonucleotides.	Goksenin AY, Zahurancik WJ, Lecompte KG, Taggart DJ, Suo Z, Pursell ZF	2012
A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome.	Kilkenny ML, De Piccoli G, Perera RL, Labib K, Pellegrini L	2012
Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage.	Zhang S, Zhou Y, Sarkeshik A, Yates J, Thomson TM, Zhang Z, Lee EY, Lee MY	2012
Segregation of replicative DNA polymerases during S phase: DNA polymerase ε, but not DNA polymerases α/δ, are associated with lamins throughout S phase in human cells.	Vaara M, Itkonen H, Hillukkala T, Liu Z, Nasheuer HP, Schaarschmidt D, Pospiech H, Syväoja JE	2012
Structural basis of recruitment of DNA polymerase ζ by interaction between REV1 and REV7 proteins.	Kikuchi S, Hara K, Shimizu T, Sato M, Hashimoto H	2012
HIV-1 nucleocapsid protein and the secondary structure of the binary complex formed between tRNA(Lys.3) and viral RNA template play different roles during initiation of (-) strand DNA reverse transcription.	Rong L, Liang C, Hsu M, Guo X, Roques BP, Wainberg MA	2001
Inducible expression of IkappaBalpha repressor mutants interferes with NF-kappaB activity and HIV-1 replication in Jurkat T cells.	Kwon H, Pelletier N, DeLuca C, Genin P, Cisternas S, Lin R, Wainberg MA, Hiscott J	1998
Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction.	Arts EJ, Li X, Gu Z, Kleiman L, Parniak MA, Wainberg MA	1994
Isolation and characterization of cDNA for DREF, a promoter-activating factor for Drosophila DNA replication-related genes.	Hirose F, Yamaguchi M, Kuroda K, Omori A, Hachiya T, Ikeda M, Nishimoto Y, Matsukage A	1996
A nucleotide sequence essential for the function of DRE, a common promoter element for Drosophila DNa replication-related genes.	Yamaguchi M, Hayashi Y, Nishimoto Y, Hirose F, Matsukage A	1995
In vitro initiation of DNA replication in simian virus 40 chromosomes.	Decker RS, Yamaguchi M, Possenti R, Bradley MK, DePamphilis ML	1987
Novel 8-base pair sequence (Drosophila DNA replication-related element) and specific binding factor involved in the expression of Drosophila genes for DNA polymerase alpha and proliferating cell nuclear antigen.	Hirose F, Yamaguchi M, Handa H, Inomata Y, Matsukage A	1993
Identification and subcellular localization of the polypeptide for chick DNA primase with a specific monoclonal antibody.	Hirose F, Yamamoto S, Yamaguchi M, Matsukage A	1988
Regulation of replication protein A functions in DNA mismatch repair by phosphorylation.	Guo S, Zhang Y, Yuan F, Gao Y, Gu L, Wong I, Li GM	2006
Kinetics of inhibition of endogenous human immunodeficiency virus type 1 reverse transcription by 2',3'-dideoxynucleoside 5'-triphosphate, tetrahydroimidazo-[4,5,1-jk][1,4]-benzodiazepin-2(1H)-thion e, and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives.	Debyser Z, Vandamme AM, Pauwels R, Baba M, Desmyter J, De Clercq E	1992
A Substitution in the Fingers Domain of DNA Polymerase Delta Reduces Fidelity by Altering Nucleotide Discrimination in the Catalytic Site.	Prindle MJ, Schmitt MW, Parmeggiani F, Loeb LA	2013
Effects of non-nucleoside inhibitors of human immunodeficiency virus type 1 in cell-free recombinant reverse transcriptase assays.	Gu Z, Quan Y, Li Z, Arts EJ, Wainberg MA	1995
A HIV-1 minimal gag protein is superior to nucleocapsid at in vitro annealing and exhibits multimerization-induced inhibition of reverse transcription.	Roldan A, Warren OU, Russell RS, Liang C, Wainberg MA	2005
The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2', 3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro.	Gu Z, Fletcher RS, Arts EJ, Wainberg MA, Parniak MA	1994
Identification of CFDD (common regulatory factor for DNA replication and DREF genes) and role of its binding site in regulation of the proliferating cell nuclear antigen gene promoter.	Hayashi Y, Hirose F, Nishimoto Y, Shiraki M, Yamagishi M, Matsukage A, Yamaguchi M	1997
D-type cyclin-binding regions of proliferating cell nuclear antigen.	Matsuoka S, Yamaguchi M, Matsukage A	1994
Repression of regulatory factor for Drosophila DNA replication-related gene promoters by zerknüllt homeodomain protein.	Hirose F, Yamaguchi M, Matsukage A	1994
Repression of polyoma virus DNA replication by 5'-flanking region of mouse DNA polymerase beta gene containing transcriptional silencer elements.	Yamaguchi M, Matsukage A	1989
Human telomerase reverse transcriptase (hTERT) is a novel target of the Wnt/β-catenin pathway in human cancer.	Zhang Y, Toh L, Lau P, Wang X	2012
BRCA1 interaction with human papillomavirus oncoproteins.	Zhang Y, Fan S, Meng Q, Ma Y, Katiyar P, Schlegel R, Rosen EM	2005
Bcl2 impedes DNA mismatch repair by directly regulating the hMSH2-hMSH6 heterodimeric complex.	Hou Y, Gao F, Wang Q, Zhao J, Flagg T, Zhang Y, Deng X	2007
Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.	Ren J, Diprose J, Warren J, Esnouf RM, Bird LE, Ikemizu S, Slater M, Milton J, Balzarini J, Stuart DI, Stammers DK	2000
Kinetics of inhibition of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by the novel HIV-1-specific nucleoside analogue [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5 "- (4"-amino-1",2"-oxathiole-2",2"-dioxide)thymine (TSAO-T).	Balzarini J, Pérez-Pérez MJ, San-Félix A, Camarasa MJ, Bathurst IC, Barr PJ, De Clercq E	1992
Resistance of HIV-1 reverse transcriptase against [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2''-dioxide)] (TSAO) derivatives is determined by the mutation Glu138-->Lys on the p51 subunit.	Jonckheere H, Taymans JM, Balzarini J, Velázquez S, Camarasa MJ, Desmyter J, De Clercq E, Anné J	1994
The acyclic 2,4-diaminopyrimidine nucleoside phosphonate acts as a purine mimetic in HIV-1 reverse transcriptase DNA polymerization.	Herman BD, Votruba I, Holy A, Sluis-Cremer N, Balzarini J	2010
Functional characterization of chimeric reverse transcriptases with polypeptide subunits of highly divergent HIV-1 group M and O strains.	Menéndez-Arias L, Abraha A, Quiñones-Mateu ME, Mas A, Camarasa MJ, Arts EJ	2001
The human lagging strand DNA polymerase δ holoenzyme is distributive.	Hu Z, Perumal SK, Yue H, Benkovic SJ	2012
Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein.	Maddukuri L, Ketkar A, Eddy S, Zafar MK, Griffin WC, Eoff RL	2012
GCN5 protects vertebrate cells against UV-irradiation via controlling gene expression of DNA polymerase η.	Kikuchi H, Kuribayashi F, Imajoh-Ohmi S, Nishitoh H, Takami Y, Nakayama T	2012
Single-Molecule Investigation of Substrate Binding Kinetics and Protein Conformational Dynamics of a B-Family Replicative DNA Polymerase.	Maxwell BA, Suo Z	2013
Translesion synthesis past acrolein-derived DNA adducts by human mitochondrial DNA polymerase γ	Kasiviswanathan R, Minko IG, Lloyd RS, Copeland WC	2013
The Human Tim/Tipin Complex Directly Interacts with DNA Polymerase {epsilon} and Stimulates its Synthetic Activity.	Aria V, De Felice M, Di Perna R, Uno S, Masai H, Syvaoja JE, van Loon B, Hubscher U, Pisani FM	2013
Reverse transcriptase-associated ribonuclease H does not require zinc for catalysis.	Modak MJ, Srivastava A	1979
Analysis of the role of glutamine 190 in the catalytic mechanism of murine leukemia virus reverse transcriptase.	Jin J, Kaushik N, Singh K, Modak MJ	1999
Biochemistry of terminal deoxynucleotidyltransferase. Identification and unity of ribo- and deoxyribonucleoside triphosphate binding site in terminal deoxynucleotidyltransferase.	Pandey VN, Modak MJ	1989
Enzymatic activities associated with avian and murine retroviral DNA polymerases. Catalysis of and active site involvement in pyrophosphate exchange and pyrophosphorolysis reactions.	Srivastava A, Modak MJ	1980
Purification and properties of Rauscher leukemia virus DNA polymerase and selective inhibition of mammalian viral reverse transcriptase by inorganic phosphate.	Modak MJ, Marcus SL	1977
Site-directed mutagenesis of Moloney murine leukemia virus reverse transcriptase. Demonstration of lysine 103 in the nucleotide binding site.	Basu A, Basu S, Modak MJ	1990
Substrate binding in human immunodeficiency virus reverse transcriptase. An analysis of pyridoxal 5'-phosphate sensitivity and identification of lysine 263 in the substrate-binding domain.	Basu A, Tirumalai RS, Modak MJ	1989
Substrate binding domain of murine leukemia virus reverse transcriptase. Identification of lysine 103 and lysine 421 as binding site residues.	Basu A, Nanduri VB, Gerard GF, Modak MJ	1988
Phenylglyoxal as a template site-specific reagent for DNA and RNA polymerases. Selective inhibition of initiation.	Srivastava A, Modak MJ	1980
The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse.	Watanabe N, Mii S, Asai N, Asai M, Niimi K, Ushida K, Kato T, Enomoto A, Ishii H, Takahashi M, Murakumo Y	2013
Insights into the Conformation of Aminofluorene-dG Adduct in a DNA Polymerase Active Site.	Vaidyanathan VG, Liang F, Beard WA, Shock DD, Wilson SH, Cho BP	2013
dNTP-dependent conformational transitions in the fingers subdomain of Klentaq1 DNA polymerase: insights into the role of the "nucleotide-binding" state.	Rothwell PJ, Allen WJ, Sisamakis E, Kalinin S, Felekyan S, Widengren J, Waksman G, Seidel CA	2013
Characterization of the DNA primase complex isolated from the archaeon, Thermococcus kodakaraensis.	Chemnitz Galal W, Pan M, Kelman Z, Hurwitz J	2012
The Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase δ	Kamath-Loeb AS, Shen JC, Schmitt MW, Loeb LA	2012
A novel function of CRL4Cdt2: regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase.	Zhang S, Zhao H, Darzynkiewicz Z, Zhou P, Zhang Z, Lee EY, Lee MY	2013
Replisome fate upon encountering a leading strand block and clearance from DNA by recombination proteins.	McInerney P, O'Donnell ME	2007
Involvement of the beta clamp in methyl-directed mismatch repair in vitro.	Pluciennik A, Burdett V, Lukianova O, O'Donnell ME, Modrich P	2009
DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA.	Langston LD, O'Donnell ME	2008
The replication factor C clamp loader requires arginine finger sensors to drive DNA binding and proliferating cell nuclear antigen loading.	Johnson A, Yao NY, Bowman GD, Kuriyan J, O'Donnell ME	2006
Mechanism of the delta wrench in opening the beta sliding clamp.	Indiani C, O'Donnell ME	2003
Cross-utilization of the beta sliding clamp by replicative polymerases of evolutionary divergent organisms.	Klemperer N, Zhang D, Skangalis M, O'Donnell ME	2000
The E295K cancer variant of human polymerase beta favors the mismatch conformational pathway during nucleotide selection.	Eckenroth BE, Towle-Weicksel JB, Sweasy JB, Doubli Eacute S	2013
DNA polymerase alpha from Drosophila melanogaster embryos. Subunit structure.	Villani G, Sauer B, Lehman IR	1980
Fluorescence resonance energy transfer studies of DNA polymerase β: the critical role of fingers domain movements and a novel non-covalent step during nucleotide selection.	Towle-Weicksel JB, Dalal S, Sohl CD, Doublié S, Anderson KS, Sweasy JB	2014
Kinetics, structure, and mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine bypass by human DNA polymerase η.	Patra A, Nagy LD, Zhang Q, Su Y, Müller L, Guengerich FP, Egli M	2014
Mitochondrial Single-stranded DNA-binding Proteins Stimulate the Activity of DNA Polymerase γ by Organization of the Template DNA.	Ciesielski GL, Bermek O, Rosado-Ruiz FA, Hovde SL, Neitzke OJ, Griffith JD, Kaguni LS	2015
Oligodeoxyribonucleotide-primed reactions catalyzed by calf thymus polymerase.	Bollum FJ	1962
DEOXYNUCLEOTIDE-POLYMERIZING ENZYMES OF CALF THYMUS GLAND. I. LARGE SCALE PURIFICATION OF TERMINAL AND REPLICATIVE DEOXYNUCLEOTIDYL TRANSFERASES.	YONEDA M, Bollum FJ	1965
DNA polymerase gamma from Xenopus laevis. II. A 3'----5' exonuclease is tightly associated with the DNA polymerase activity.	Insdorf NF, Bogenhagen DF	1989
The nature of the DNA substrate influences pre-catalytic conformational changes of DNA polymerase β.	Huang J, Alnajjar KS, Mahmoud MM, Eckenroth BE, Doublie S, Sweasy J	2018
Enzymatic synthesis of deoxyribonucleic acid. XII. A polymer of deoxyguanylate and deoxycytidylate.	RADDING CM, JOSSE J, Kornberg A	1962
On the fidelity of DNA replication. The accuracy of T4 DNA polymerases in copying phi X174 DNA in vitro.	Kunkel TA, Loeb LA, Goodman MF	1984
Highly efficient DNA synthesis by the phage phi 29 DNA polymerase. Symmetrical mode of DNA replication.	Blanco L, Bernad A, Lázaro JM, Martín G, Garmendia C, Salas M	1989
Enzymatic synthesis of deoxyribonucleic acid. VIII. Frequencies of nearest neighbor base sequences in deoxyribonucleic acid.	JOSSE J, KAISER AD, Kornberg A	1961

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