Translesion DNA synthesis: little fingers teach tolerance.

Abstract:

DNA synthesis on a damaged template requires tolerant DNA polymerases. Crystallographic analysis has captured a Y-family polymerase synthesizing across an abasic site, providing insight into the mechanisms of DNA damage tolerance and mutation.

Polymerases:

Topics:

Structure and Structure/Function

Note:

The paper reviews results of crystallographic and biochemical studies of the archaeal Y-polymerase Dpo4.

Status:

new topics/pols set partial results complete validated

Results:

No results available for this paper.

Entry validated by:

Log in to edit reference All References

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.