Translesion DNA synthesis: little fingers teach tolerance.
Abstract:
DNA synthesis on a damaged template requires tolerant DNA polymerases. Crystallographic analysis has captured a Y-family polymerase synthesizing across an abasic site, providing insight into the mechanisms of DNA damage tolerance and mutation.
Polymerases:
Topics:
Structure and Structure/Function
Note:
The paper reviews results of crystallographic and biochemical studies of the archaeal Y-polymerase Dpo4.
Status:
| new | topics/pols set | partial results | complete | validated |
Results:
No results available for this paper.