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Boudsocq F

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Publications:

Title Authors Year Journal
The R438W polymorphism of human DNA polymerase lambda triggers cellular sensitivity to camptothecin by compromising the homologous recombination repair pathway. Boudsocq F 2010 Carcinogenesis
Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ. Boudsocq F 2009 PloS one
Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication. Boudsocq F 2009 Molecular and cellular biology
Initiation of DNA replication by a third parallel DNA strand bound in a triple-helix manner leads to strand invasion. Boudsocq F 2008 Biochemistry
Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors. Boudsocq F 2008 BMC Struct Biol
Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells. Boudsocq F 2007 Nucleic acids research
The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells. Boudsocq F 2006 Nucleic acids research
Modulation of cellular response to cisplatin by a novel inhibitor of DNA polymerase beta. Boudsocq F 2005 Mol Pharmacol
Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution. Boudsocq F 2004 Nat Biotechnol
Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts. Boudsocq F 2004 Molecular cell
Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication. Boudsocq F 2004 The Journal of biological chemistry
Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Boudsocq F 2004 Proceedings of the National Academy of Sciences of the United States of America
Replication of a cis-syn thymine dimer at atomic resolution. Boudsocq F 2003 Nature
Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass. Boudsocq F 2002 DNA repair
Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site. Boudsocq F 2002 The Journal of biological chemistry
Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients. Boudsocq F 2002 Proceedings of the National Academy of Sciences of the United States of America
Biochemical characterization of human DNA polymerase iota provides clues to its biological function. Boudsocq F 2001 Biochem Soc Trans
Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Boudsocq F 2001 Cell
Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta. Boudsocq F 2001 Nucleic acids research

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