Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta.

Polymerases:

Topics:

Historical Protein Properties (MW, pI, ...), Nucleotide Analogs / Template Lesions, Fidelity

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
Dpo4 Boudsocq F2001 Molecular Weight 4.019E+04 Dalton
Dpo4 Boudsocq F2001 Cloned or native Cloned in E. coli
Dpo4 Boudsocq F2001 Template lesions Bypasses Reaction: Nucleotide incorporation; Substrate: dATP; DNA lesion: Apurinic/Apyrimidinic (AP) site
Dpo4 Boudsocq F2001 Template lesions Bypasses Reaction: Nucleotide incorporation; Substrate: dATP; DNA lesion: TT Cyclobutane Pyrimidine Dimer
Dpo4 Boudsocq F2001 Tagged No
Dpo4 Boudsocq F2001 Full length or truncated Full length
Dpo4 Boudsocq F2001 Isoelectric Point pH 9.11

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