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Tsai MD

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Publications:

Title Authors Year Journal
Solution structures of 2 : 1 and 1 : 1 DNA polymerase-DNA complexes probed by ultracentrifugation and small-angle X-ray scattering. Tsai MD 2008 Nucleic acids research
Mismatched dNTP incorporation by DNA polymerase beta does not proceed via globally different conformational pathways. Tsai MD 2008 Nucleic acids research
Structure and function of 2:1 DNA polymerase.DNA complexes. Tsai MD 2008 J Cell Physiol
Altered order of substrate binding by DNA polymerase X from African Swine Fever virus. Tsai MD 2008 Biochemistry
Mismatched and matched dNTP incorporation by DNA polymerase beta proceed via analogous kinetic pathways. Tsai MD 2008 Biochemistry
Use of damaged DNA and dNTP substrates by the error-prone DNA polymerase X from African swine fever virus. Tsai MD 2007 Biochemistry
Mechanistic comparison of high-fidelity and error-prone DNA polymerases and ligases involved in DNA repair. Tsai MD 2006 Chem Rev
Use of viscogens, dNTPalphaS, and rhodium(III) as probes in stopped-flow experiments to obtain new evidence for the mechanism of catalysis by DNA polymerase beta. Tsai MD 2005 Biochemistry
Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase beta. Tsai MD 2002 Biochemistry
Solution structure of a viral DNA polymerase X and evidence for a mutagenic function. Tsai MD 2001 Nature structural biology
Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes. Tsai MD 2001 Biochemistry
DNA polymerase beta: pre-steady-state kinetic analyses of dATP alpha S stereoselectivity and alteration of the stereoselectivity by various metal ions and by site-directed mutagenesis. Tsai MD 2001 Biochemistry
A DNA polymerase with specificity for five base pairs. Tsai MD 2001 Journal of the American Chemical Society
DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity. Tsai MD 2000 Biochemistry
DNA polymerase beta: effects of gapped DNA substrates on dNTP specificity, fidelity, processivity and conformational changes. Tsai MD 1998 Biochem J
DNA polymerase beta: analysis of the contributions of tyrosine-271 and asparagine-279 to substrate specificity and fidelity of DNA replication by pre-steady-state kinetics. Tsai MD 1997 Biochem J
DNA polymerase beta: multiple conformational changes in the mechanism of catalysis. Tsai MD 1997 Biochemistry
DNA polymerase beta: structure-fidelity relationship from Pre-steady-state kinetic analyses of all possible correct and incorrect base pairs for wild type and R283A mutant. Tsai MD 1997 Biochemistry
DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelity. Tsai MD 1996 Biochemistry
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