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Bernad A

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Publications:

Title Authors Year Journal
Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ. Bernad A 2013 PloS one
A role for DNA polymerase mu in the emerging DJH rearrangements of the postgastrulation mouse embryo. Bernad A 2009 Molecular and cellular biology
Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair. Bernad A 2009 PLoS Genet
Polymerase mu is up-regulated during the T cell-dependent immune response and its deficiency alters developmental dynamics of spleen centroblasts. Bernad A 2005 European journal of immunology
Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate. Bernad A 2004 Nucleic acids research
DNA polymerase mu, a candidate hypermutase? Bernad A 2001 Philosophical transactions of the Royal Society of London. Series B, Biological sciences
DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis. Bernad A 2000 Journal of molecular biology
DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells. Bernad A 2000 The EMBO journal
Site-directed mutagenesis at the Exo III motif of phi 29 DNA polymerase; overlapping structural domains for the 3'-5' exonuclease and strand-displacement activities. Bernad A 1992 The EMBO journal
Initiation of phi 29 DNA replication occurs at the second 3' nucleotide of the linear template: a sliding-back mechanism for protein-primed DNA replication. Bernad A 1992 Proceedings of the National Academy of Sciences of the United States of America
Evidence favouring the hypothesis of a conserved 3'-5' exonuclease active site in DNA-dependent DNA polymerases. Bernad A 1992 Gene
The bacteriophage phi 29 DNA polymerase, a proofreading enzyme. Bernad A 1992 The Journal of biological chemistry
DNA-independent deoxynucleotidylation of the phi 29 terminal protein by the phi 29 DNA polymerase. Bernad A 1992 The Journal of biological chemistry
Phi 29 DNA polymerase active site. Mutants in conserved residues Tyr254 and Tyr390 are affected in dNTP binding. Bernad A 1992 The Journal of biological chemistry
Metal activation of synthetic and degradative activities of phi 29 DNA polymerase, a model enzyme for protein-primed DNA replication. Bernad A 1992 Biochemistry
MIP1 DNA polymerase of S. cerevisiae: structural similarity with the E. coli DNA polymerase I-type enzymes. Bernad A 1991 Nucleic acids research
Characterization and mapping of the pyrophosphorolytic activity of the phage phi 29 DNA polymerase. Involvement of amino acid motifs highly conserved in alpha-like DNA polymerases. Bernad A 1991 The Journal of biological chemistry
A general structure for DNA-dependent DNA polymerases. Bernad A 1991 Gene
Site-directed mutagenesis of the YCDTDS amino acid motif of the phi 29 DNA polymerase. Bernad A 1990 Gene
The highly conserved amino acid sequence motif Tyr-Gly-Asp-Thr-Asp-Ser in alpha-like DNA polymerases is required by phage phi 29 DNA polymerase for protein-primed initiation and polymerization. Bernad A 1990 Proceedings of the National Academy of Sciences of the United States of America
Structural and functional analysis of temperature-sensitive mutants of the phage phi 29 DNA polymerase. Bernad A 1990 Nucleic acids research
A conserved 3'----5' exonuclease active site in prokaryotic and eukaryotic DNA polymerases. Bernad A 1989 Cell
Highly efficient DNA synthesis by the phage phi 29 DNA polymerase. Symmetrical mode of DNA replication. Bernad A 1989 The Journal of biological chemistry
Protein-primed replication of bacteriophage phi 29 DNA. Bernad A 1988 Biochimica et biophysica acta
Effect of NH4+ ions on phi 29 DNA-protein p3 replication: formation of a complex between the terminal protein and the DNA polymerase. Bernad A 1987 J Virol
Structural and functional relationships between prokaryotic and eukaryotic DNA polymerases. Bernad A 1987 The EMBO journal
Replication of phage phi 29 DNA in vitro: role of the viral protein p6 in initiation and elongation. Bernad A 1986 Nucleic acids research
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