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Yang WW

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Publications:

Title Authors Year Journal
Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η Yang WW 2013 Proceedings of the National Academy of Sciences of the United States of America
Escherichia coli UmuC active site mutants: Effects on translesion DNA synthesis, mutagenesis and cell survival. Yang WW 2012 DNA repair
Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity. Yang WW 2012 Nucleic acids research
Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin. Yang WW 2012 Proceedings of the National Academy of Sciences of the United States of America
Watching DNA polymerase η make a phosphodiester bond. Yang WW 2012 Nature
Structure and mechanism of human DNA polymerase η Yang WW 2011 Nature
Structure and mechanism of human DNA polymerase eta. Yang WW 2010 Nature
Structural insight into translesion synthesis by DNA Pol II. Yang WW 2009 Cell
Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. Yang WW 2007 Journal of molecular biology
What a difference a decade makes: insights into translesion DNA synthesis. Yang WW 2007 Proceedings of the National Academy of Sciences of the United States of America
Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Yang WW 2005 The EMBO journal
Portraits of a Y-family DNA polymerase. Yang WW 2005 FEBS letters
Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Yang WW 2004 Proceedings of the National Academy of Sciences of the United States of America
Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts. Yang WW 2004 Molecular cell
Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication. Yang WW 2004 The Journal of biological chemistry
Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota. Yang WW 2004 The Journal of biological chemistry
Nuclear magnetic resonance structures of the zinc finger domain of human DNA polymerase-alpha. Yang WW 2003 Biochimica et biophysica acta
Damage repair DNA polymerases Y. Yang WW 2003 Current opinion in structural biology
Replication of a cis-syn thymine dimer at atomic resolution. Yang WW 2003 Nature
Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass. Yang WW 2002 DNA repair
Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Yang WW 2001 Cell
Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein. Yang WW 2001 The EMBO journal
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