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Polymerase: Human Pol lamba

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Polymerase Reference Property Result Context
Human Pol lamba Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. Molecular Weight 68kD Technique: Gel Filtration
Human Pol lamba Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. Cloned or native Cloned in E. coli
Human Pol lamba Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. Tagged Yes
Human Pol lamba Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. Tag Name His
Human Pol lamba Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. Full length or truncated Full length
Human Pol lamba Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. Processivity 1bp
Human Pol lamba Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. Specific Activity 3.37 units/mg Technique: Polymerase assay (poly[d(AT)]
Human Pol lamba DNA polymerase lambda, a novel DNA repair enzyme in human cells. Molecular Weight 6.8E+04 Dalton Technique: SDS-PAGE
Human Pol lamba DNA polymerase lambda, a novel DNA repair enzyme in human cells. 3-5' Exonuclease (proofreading) No
Human Pol lamba DNA polymerase lambda, a novel DNA repair enzyme in human cells. Cloned or native Cloned in E. coli
Human Pol lamba DNA polymerase lambda, a novel DNA repair enzyme in human cells. Nucleotide Substitution Rate 0.0009 errors/bp Technique: M13mp2 forward mutation assay
Human Pol lamba DNA polymerase lambda, a novel DNA repair enzyme in human cells. Full length or truncated Full length
Human Pol lamba DNA polymerase lambda, a novel DNA repair enzyme in human cells. Processivity 6bp
Human Pol lamba DNA polymerase lambda, a novel DNA repair enzyme in human cells. KM 0.5uM Reaction: Nucleotide incorporation; Substrate: dNTPs
Human Pol lamba Loop 1 modulates the fidelity of DNA polymerase {lambda} KM 0.39uM Reaction: Nucleotide incorporation; Substrate: dATP; Technique: Steady State
Human Pol lamba Loop 1 modulates the fidelity of DNA polymerase {lambda} KM 7.4uM Reaction: Nucleotide incorporation; Substrate: dGTP; Technique: Steady State
Human Pol lamba Loop 1 modulates the fidelity of DNA polymerase {lambda} kcat 0.012 /second Reaction: Nucleotide incorporation; Substrate: dATP; Technique: Steady State
Human Pol lamba Loop 1 modulates the fidelity of DNA polymerase {lambda} kcat 0.00014 /second Reaction: Nucleotide incorporation; Substrate: dGTP; Technique: Steady State
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Terminal Transferase Yes
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Molecular Weight 68kD
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. 3-5' Exonuclease (proofreading) No
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. 5-3' Exonuclease No
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Template lesions Bypasses Reaction: Nucleotide incorporation; DNA lesion: 8-oxo-dG
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Full length or truncated Full length
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Vmax 2.1 /second Reaction: Nucleotide incorporation; Substrate: dNTPs
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Other accessory protein(s) PCNA, CDK2/CyclinA
Human Pol lamba DNA polymerase family X: function, structure, and cellular roles. Gap Filling Yes
Human Pol lamba Structure and function of a mycobacterial NHEJ DNA repair polymerase. Terminal Transferase No
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. Terminal Transferase No
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. 3-5' Exonuclease (proofreading) No
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. Frameshift Error Rate 0.0049 errors/bp Technique: M13mp2 forward mutation assay
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. Nucleotide Substitution Rate 0.0009 errors/bp Technique: M13mp2 forward mutation assay
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. Full length or truncated Full length
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. Gap Filling Yes

Version:20240425

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.