Loop 1 modulates the fidelity of DNA polymerase {lambda}

Abstract:

Differences in the substrate specificity of mammalian family X DNA ...

Polymerases:

Topics:

Kinetic Parameters, Structure and Structure/Function

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
Human Pol lamba Loop 1 modulates the fidelity of DNA polymerase {lambda} KM 0.39uM Reaction: Nucleotide incorporation; Substrate: dATP; Technique: Steady State
Human Pol lamba Loop 1 modulates the fidelity of DNA polymerase {lambda} KM 7.4uM Reaction: Nucleotide incorporation; Substrate: dGTP; Technique: Steady State
Human Pol lamba Loop 1 modulates the fidelity of DNA polymerase {lambda} kcat 0.012 /second Reaction: Nucleotide incorporation; Substrate: dATP; Technique: Steady State
Human Pol lamba Loop 1 modulates the fidelity of DNA polymerase {lambda} kcat 0.00014 /second Reaction: Nucleotide incorporation; Substrate: dGTP; Technique: Steady State

Entry validated by:

Structures:

3MGI 3MGH