The frameshift infidelity of human DNA polymerase lambda. Implications for function.

Abstract:

DNA polymerase lambda (Pol lambda) is a member of the Pol X family ...

Polymerases:

Topics:

Fidelity, Nucleotide Incorporation, Exonuclease Activity, Terminal Transferase

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. Terminal Transferase No
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. 3-5' Exonuclease (proofreading) No
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. Frameshift Error Rate 0.0049 errors/bp Technique: M13mp2 forward mutation assay
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. Nucleotide Substitution Rate 0.0009 errors/bp Technique: M13mp2 forward mutation assay
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. Full length or truncated Full length
Human Pol lamba The frameshift infidelity of human DNA polymerase lambda. Implications for function. Gap Filling Yes

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