Human Pol mu

From H. sapiens (genes: POLM)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Human Pol mu.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Human Pol mu is a family X enzyme from H. sapiens.

Selected Properties for Human Pol mu:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (3) No (1) no data no data no data
Year Authors Title Results by property
S Sharma, CM Helchowski, CE Canman The roles of DNA polymerase ζ and the...
2012 Maria Jose Martin, Maria V Garcia-Ortiz, Veronica Esteban, Luis Blanco Ribonucleotides and manganese ions im...
2012 Shanen M Sherrer, Laura E Sanman, Cynthia X Xia, Eric R Bolin, Chanchal K Malik, Georgia Efthimiopoulos, Ashis K Basu, Zucai Suo Kinetic Analysis of the Bypass of a B...
2012 Yaofeng Zhao, Christian Biertümpfel, Mark T Gregory, Yue-Jin Hua, Fumio Hanaoka, Wei Wen Yang Structural basis of human DNA polymer...
2012 Ajay Ummat, Olga Rechkoblit, Rinku Jain, Jayati Roy Choudhury, Robert E Johnson, Timothy D Silverstein, Angeliki Buku, Samer Lone, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structural basis for cisplatin DNA da...
2012 Takuro Matsumoto, Kaori Go, Mariko Hyodo, Kotaro Koiwai, So Maezawa, Takahide Hayano, Masahiro Suzuki, Osamu Koiwai BRCT domain of DNA polymerase μ has D...
2010 Romain Chayot, Anne Danckaert, Benjamin Montagne, Miria Ricchetti Lack of DNA polymerase mu affects the...
2010 Mark D Sutton Coordinating DNA polymerase traffic d...
2010 Jennifer Yamtich, Joann B Sweasy DNA polymerase family X: function, st... Full length or truncated,Gap fill,Terminal Transferase,3-5' exo,5-3' exo,Molecular Weight,Vmax,Template lesions,All properties
2009 Paula Andrade, María José Martín, Raquel Juárez, Francisco López de Saro, Luis Blanco Limited terminal transferase in human...
2007 Robert S Pitcher, Nigel C Brissett, Angel J Picher, Paula Andrade, Raquel Juarez, Darren Thompson, Gavin C Fox, Luis Blanco, Aidan J Doherty Structure and function of a mycobacte... Terminal Transferase,All properties
2007 Andrea F Moon, Miguel Garcia-Diaz, Vinod K Batra, William A Beard, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, Lars C Pedersen The X family portrait: structural ins...
2007 Eugene F DeRose, Michael W Clarkson, Steven A Gilmore, Cristina J Galban, Ashutosh Tripathy, Jody M Havener, Geoffrey A Mueller, Dale A Ramsden, Robert E London, Andrew L Lee Solution structure of polymerase mu's...
2006 Raquel Juárez, José F Ruiz, Stephanie A Nick McElhinny, Dale A Ramsden, Luis Blanco A specific loop in human DNA polymera...
2004 Michelle P Roettger, Kevin A Fiala, Susmitha Sompalli, Yuxia Dong, Zucai Suo Pre-steady-state kinetic studies of t...
2004 Shay Covo, Luis Blanco, Zvi Livneh Lesion bypass by human DNA polymerase...
2004 José F Ruiz, Daniel Lucas, Esther García-Palomero, Ana I Saez, Manuel A González, Miguel A Piris, Antonio Bernad, Luis Blanco Overexpression of human DNA polymeras...
2003 José F Ruiz, Raquel Juárez, Miguel García-Díaz, Gloria Terrados, Angel J Picher, Sergio González-Barrera, Antonio R Fernández de Henestrosa, Luis Blanco Lack of sugar discrimination by human...
2003 Stephanie A Nick McElhinny, Dale A Ramsden Polymerase mu is a DNA-directed DNA/R...
2003 Jody M Havener, Stephanie A Nick McElhinny, Ekaterina Bassett, Michele Gauger, Dale A Ramsden, Stephen G Chaney Translesion synthesis past platinum D...
2002 Yongqing Zhang, Xiaoming Wu, Dongyu Guo, Olga Rechkoblit, John-Stephen Taylor, Nicholas E Geacintov, Zhengqiang Wang Lesion bypass activities of human DNA...
2002 Jean-Baptiste Duvauchelle, Luis Blanco, Robert P P Fuchs, Agnes M Cordonnier Human DNA polymerase mu (Pol mu) exhi...
2001 Yongqing Zhang, Xiaoming Wu, Fenghua Yuan, Zhongwen Xie, Zhengqiang Wang Highly frequent frameshift DNA synthe... Cloned or native,Tagged,Tag Name,Full length or truncated,3-5' exo,Molecular Weight,All properties
2001 Patricia J Gearhart, Richard D Wood Emerging links between hypermutation ... Associated condition,All properties
2000 Orlando Domínguez, José F Ruiz, Teresa Laín de Lera, Miguel García-Díaz, Manuel A González, Tomas Kirchhoff, Carlos Martínez-A, Antonio Bernad, Luis Blanco DNA polymerase mu (Pol mu), homologou... Cloned or native,Full length or truncated,Terminal Transferase,3-5' exo,Molecular Weight,All properties
Protein sequence:

Using Polbase tables:

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