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Polymerase: Human Pol delta

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Polymerase Reference Property Result Context
Human Pol delta The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability. 3-5' Exonuclease (proofreading) Yes
Human Pol delta Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. Molecular Weight 173kD
Human Pol delta Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. 3-5' Exonuclease (proofreading) Yes
Human Pol delta Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. 5-3' Exonuclease No
Human Pol delta Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. 3-5' Exo Specific Activity 451 units/mg
Human Pol delta Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. Full length or truncated Full length
Human Pol delta Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. RNase H No
Human Pol delta Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. Processivity 1kb
Human Pol delta Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. Specific Activity 132 units/mg Technique: Polymerase Assay (M13 DNA)
Human Pol delta Thermostable DNA polymerases. Molecular Weight 1.25E+05 Dalton
Human Pol delta Thermostable DNA polymerases. 3-5' Exonuclease (proofreading) Yes
Human Pol delta Thermostable DNA polymerases. 5-3' Exonuclease No
Human Pol delta Thermostable DNA polymerases. Full length or truncated Full length
Human Pol delta Kinetic analysis of nucleotide incorporation by mammalian DNA polymerase delta. KM 0.067uM Reaction: Nucleotide incorporation; Substrate: dCTP; Technique: Steady State (With PCNA)
Human Pol delta Kinetic analysis of nucleotide incorporation by mammalian DNA polymerase delta. KM 1.2uM Reaction: Nucleotide incorporation; Substrate: dCTP; Technique: Steady State (Without PCNA)
Human Pol delta Kinetic analysis of nucleotide incorporation by mammalian DNA polymerase delta. kcat 0.36 /minute Reaction: Nucleotide incorporation; Substrate: dCTP; Technique: Steady State (With PCNA)
Human Pol delta Kinetic analysis of nucleotide incorporation by mammalian DNA polymerase delta. kcat 0.3 /minute Reaction: Nucleotide incorporation; Substrate: dCTP; Technique: Steady State (Without PCNA)
Human Pol delta Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases. KM 71uM Reaction: Nucleotide incorporation; Substrate: dATP; Technique: Steady State
Human Pol delta Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. 3-5' Exonuclease (proofreading) Yes
Human Pol delta Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. 5-3' Exonuclease No
Human Pol delta Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. Nucleotide Substitution Rate 1E-05 errors/bp
Human Pol delta Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands. Template lesions Bypasses Reaction: Nucleotide incorporation; DNA lesion: TC 6,4 Photodimer
Human Pol delta Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. Cloned or native Insect cells
Human Pol delta Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. Tagged No
Human Pol delta Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. Full length or truncated Full length
Human Pol delta Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. Storage requirements Liquid nitrogen

Version:20240425

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.