Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands.
Narita T, Tsurimoto T, Yamamoto J, Nishihara K, Ogawa K, Ohashi E, Evans T, Iwai S, Takeda S, Hirota K
Genes to cells : devoted to molecular & cellular mechanisms (2010), Volume 15, Page 1228
Abstract:
Polymerases:
Topics:
Nucleotide Analogs / Template Lesions, Nucleotide Incorporation
Status:
new | topics/pols set | partial results | complete | validated |
Results:
Polymerase | Reference | Property | Result | Context |
---|---|---|---|---|
Human Pol delta | Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands. | Template lesions | Bypasses | Reaction: Nucleotide incorporation; DNA lesion: TC 6,4 Photodimer |