Sce Pol alpha

show help

Welcome to the Polymerase Page

This page presents all the information in Polbase for Sce Pol alpha.


At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.


If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.


All references that refer to this Polymerase are listed with their topics and paper's title in the References table.


All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Sce Pol alpha is a family B enzyme from S. cerevisiea.

Selected Properties for Sce Pol alpha:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no consensus no consensus no data 3.4e-03 errors/bp (1) no data
Year Authors Title Results by property
2010 Mark D Sutton Coordinating DNA polymerase traffic d...
2010 Erik Johansson, Stuart A Macneill The eukaryotic replicative DNA polyme...
2009 Sebastian Klinge, Rafael Núñez-Ramírez, Oscar Llorca, Luca Pellegrini 3D architecture of DNA Pol alpha reve...
2008 Anne M Casper, Piotr A Mieczkowski, Malgorzata Gawel, Thomas D Petes Low levels of DNA polymerase alpha in...
2004 Atsuko Niimi, Siripan Limsirichaikul, Shonen Yoshida, Shigenori Iwai, Chikahide Masutani, Fumio Hanaoka, Eric T Kool, Yoshitaka Nishiyama, Motoshi Suzuki Palm mutants in DNA polymerases alpha...
2004 Robin M Ricke, Anja-Katrin Bielinsky Mcm10 regulates the stability and chr...
2003 Siripan Limsirichaikul, Masanori Ogawa, Atsuko Niimi, Shigenori Iwai, Takashi Murate, Shonen Yoshida, Motoshi Suzuki The Gly-952 residue of Saccharomyces ...
2003 Subhasis B Biswas, Sujata M Khopde, Fan xiu Zhu Fx, Esther E Biswas Subunit interactions in the assembly ...
2003 Masanori Ogawa, Siripan Limsirichaikul, Atsuko Niimi, Shigenori Iwai, Shonen Yoshida, Motoshi Suzuki Distinct function of conserved amino ... Cloned or native,Tagged,Full length or truncated,Specific Activity,Processivity,Nucleotide Substitution Rate,All properties
1997 F X Zhu, Esther E Biswas, Subhasis B Biswas Purification and characterization of ... 5-3' exo,RNase H,All properties
1997 J Wittmeyer, T Formosa The Saccharomyces cerevisiae DNA poly...
1994 S H Leem, P A Ropp, Akio Sugino The yeast Saccharomyces cerevisiae DN...
1993 Zhengqiang Wang, Xiaoming Wu, Errol C Friedberg DNA repair synthesis during base exci...
1991 Thomas A Kunkel, J D Roberts, Akio Sugino The fidelity of DNA synthesis by the ...
1991 R G Brooke, R Singhal, David C Hinkle, L B Dumas Purification and characterization of ... Cloned or native,Full length or truncated,Processivity,3-5' exo,KM,Molecular Weight,All properties
1990 Robert K Hamatake, H Hasegawa, Alan B Clark, Katarzyna Bebenek, Thomas A Kunkel, Akio Sugino Purification and characterization of ... Specific Activity,Processivity,3-5' exo,5-3' exo,KM,Molecular Weight,All properties
1977 L M Chang DNA polymerases from bakers' yeast.
1974 U Wintersberger Absence of a low-molecular-weight DNA...
1970 U Wintersberger, E Wintersberger Studies on deoxyribonucleic acid poly...
1967 H Eckstein, V Paduch, H Hilz Synchronized yeast cells. 3. DNA synt...
Protein sequence:
DNA sequence:
Name 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Sce Pol alpha Y951P 3.4e-03 errors/bp (1)

Using Polbase tables:


Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).


It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.