HIV RT K103N

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This page presents all the information in Polbase for HIV RT K103N.

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Mutant of: HIV RT (K103N)

HIV RT K103N is a family RT enzyme from HIV. From the Los Alamos National Labs HIV Mutant database (now offline):|id:401|codon:AAA>AAC|drugs:ADAMII|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:>28-fold. Tested against a site-directed mutant. "From the Los Alamos National Labs HIV Mutant database (now offline):|id:402|codon:AAA>AAC|drugs:BHAP U-87201E "From the Los Alamos National Labs HIV Mutant database (now offline):|id:403|codon:AAA>AAC|drugs:BI-RG-587 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:404|codon:AAA>AAC|drugs:DMP-266 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:405|codon:AAA>AAC|drugs:L-697 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:406|codon:AAA>AAC|drugs:L-697 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:408|codon:AAA>AAC|drugs:TIBO R82913|class:HIV-1 Specific RT Inhibitor (NNRTI)|notes:>100-fold alone. K103N/Y181C: > 1 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:409|codon:AAA>AAC|drugs:UC-10 "From the Los Alamos National Labs HIV Mutant database (now offline):|id:410|codon:AAA>AAC|drugs:UC-81

Selected Properties for HIV RT K103N:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
no data no data no data no data no data
Year Authors Title Results by property
2010 Michael L Mitchell, Jong Chan Son, Ill Young Lee, Chong-Kyo Lee, Hae Soo Kim, Hongyan Guo, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Gene Eisenberg, Romas Geleziunas, Lianhong Xu, Choung U Kim Mitchell ML2010 RT,All properties
2010 Eric B Lansdon, Katherine M Brendza, Magdeleine Hung, Ruth Wang, Susmith Mukund, Debi Jin, Gabriel Birkus, Nilima Kutty, Xiaohong Liu Lansdon EB2010 RT,All properties
2010 Romuald Corbau, Julie Mori, Chris Phillips, Lesley Fishburn, Alex Martin, Charles Mowbray, Wendy Panton, Caroline Smith-Burchnell, Adele Thornberry, Heather Ringrose, Thorsten Knöchel, Steve Irving, Mike Westby, Anthony Wood, Manos Perros Corbau R2010 RT,All properties
2010 Denis J Kertesz, Christine Brotherton-Pleiss, Minmin Yang, Zhengqiang Wang, Xianfeng Lin, Zongxing Qiu, Donald R Hirschfeld, Shelley K Gleason, Taraneh Mirzadegan, Pete W Dunten, Seth F Harris, Armando G Villaseñor, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp Kertesz DJ2010
2008 Kalyan Das, Joseph David Bauman, Arthur D Clark, Yulia Volovik Frenkel, Paul J Lewi, Aaron J Shatkin, Stephen H Hughes, Edward Arnold Das K2008 RT,All properties
2005 Johan Vingerhoets, Hilde Azijn, Els Fransen, Inky De Baere, Liesbet Smeulders, Dirk Jochmans, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune Vingerhoets J2005
2004 Kalyan Das, Arthur D Clark, Paul J Lewi, Jan Heeres, Marc R De Jonge, Lucien M H Koymans, H Maarten Vinkers, Frederik Daeyaert, Donald W Ludovici, Michael J Kukla, Bart De Corte, Robert W Kavash, Chih Y Ho, Hong Ye, Mark A Lichtenstein, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Paul L Boyer, Patrick K Clark, Stephen H Hughes, Paul A J Janssen, Edward Arnold Das K2004 RT,Associated condition,All properties
2002 Jimmy Lindberg, Snaevar Sigurdsson, Seved Löwgren, Hans O Andersson, Christer Sahlberg, Rolf Noréen, Kerstin Fridborg, Haijiang Zhang, Torsten Unge Lindberg J2002
2000 Jingshan Ren, John Milton, Kurt L Weaver, Steven A Short, David I Stuart, David K Stammers Ren J2000
2000 L T Bacheler, E D Anton, P Kudish, D Baker, J Bunville, K Krakowski, L Bolling, M Aujay, X V Wang, D Ellis, M F Becker, A L Lasut, H J George, D R Spalding, G Hollis, K Abremski Bacheler LT2000
1998 Mark Cushman, A Casimiro-Garcia, E Hejchman, J A Ruell, M Huang, C A Schaeffer, K Williamson, W G Rice, Robert W Buckheit Cushman M1998
1998 L M Demeter, P M Meehan, G Morse, M A Fischl, M Para, W Powderly, J Leedom, J Holden-Wiltse, C Greisberger, K Wood, J Timpone, L K Wathen, T Nevin, L Resnick, D H Batts, R C Reichman Demeter LM1998
1995 S D Young, S F Britcher, L O Tran, L S Payne, W C Lumma, T A Lyle, J R Huff, P S Anderson, David B Olsen, Steven S Carroll Young SD1995
1995 Jan Balzarini, María-Jesús Pérez-Pérez, S Vélazquez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson Balzarini J1995
1995 Jan Balzarini, María-Jesús Pérez-Pérez, S Vélazquez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson Balzarini J1995
1994 Douglas D Richman, D Havlir, J Corbeil, D Looney, C Ignacio, S A Spector, J Sullivan, S Cheeseman, K Barringer, D Pauletti Richman DD1994
1993 V W Byrnes, V V Sardana, W A Schleif, J H Condra, J A Waterbury, J A Wolfgang, W J Long, C L Schneider, A J Schlabach, B S Wolanski Byrnes VW1993
1993 M S Saag, E A Emini, O L Laskin, J Douglas, W I Lapidus, W A Schleif, R J Whitley, C Hildebrand, V W Byrnes, John C Kappes Saag MS1993
1993 Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, W G Tarpley, Erik De Clercq Balzarini J1993
1991 J H Nunberg, W A Schleif, E J Boots, J A O'Brien, J C Quintero, J M Hoffman, E A Emini, M E Goldman Nunberg JH1991
All Polymerases | 6 Results

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