A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. L-697,661 Working Group.

Saag MS, Emini EA, Laskin OL, Douglas J, Lapidus WI, Schleif WA, Whitley RJ, Hildebrand C, Byrnes VW, Kappes JC
The New England journal of medicine (1993), Volume 329, Page 1065
PubMed entry Publisher's site

Abstract:

The non-nucleoside reverse transcriptase inhibitors are novel ...
The non-nucleoside reverse transcriptase inhibitors are novel antiretroviral agents with selective activity in vitro against human immunodeficiency virus type 1 (HIV-1). They act through direct inhibition of reverse transcriptase and are not incorporated into DNA.

Polymerases:

HIV RT K103N,HIV RT K103Q,HIV RT Y181C,HIV RT

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new topics/pols set partial results complete validated

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