Human Pol theta

From H. sapiens (aliases:Pol Q) (genes: POLQ)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Human Pol theta.


At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.


If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.


All references that refer to this Polymerase are listed with their topics and paper's title in the References table.


All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Human Pol theta is a family A enzyme from H. sapiens.

Selected Properties for Human Pol theta:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (2) no data no data 2.4e-03 errors/bp (1) 1.0e-03-1.0e-02 errors/bp (4)
Year Authors Title Results by property
2011 M Hogg, AE Sauer-Eriksson, Erik Johansson Hogg M2011
2010 Mark D Sutton Sutton MD2010
2009 Rajendra Prasad, Matthew J Longley, Farida S Sharief, Esther W Hou, William C Copeland, Samuel H Wilson Prasad R2009
2009 Takuji Oyama, Hayato Oka, Kouta Mayanagi, Tsuyoshi Shirai, Kyoko Matoba, Ryosuke Fujikane, Yoshizumi Ishino, Kosuke Morikawa Oyama T2009
2008 Mercedes E Arana, Masayuki Seki, Richard D Wood, Igor B Rogozin, Thomas A Kunkel Arana ME2008 Full length or truncated,3-5' exo,Nucleotide Substitution Rate,Molecular Weight,Overall Error Rate,All properties
2004 Masayuki Seki, Chikahide Masutani, Lee Wei Yang, Anthony Schuffert, Shigenori Iwai, Ivet Bahar, Richard D Wood Seki M2004
2003 Masayuki Seki, Federica Marini, Richard D Wood Seki M2003
2002 Ulrich Hubscher, Giovanni Maga, Silvio Spadari Hubscher U2002
2000 Robert E Johnson, Satya Prakash, Louise Prakash Johnson RE2000 Cloned or native,Tagged,Tag Name,3-5' exo,Template lesions,Overall Error Rate,All properties
1999 Farida S Sharief, P J Vojta, P A Ropp, William C Copeland Sharief FS1999
Protein sequence:
DNA sequence:
All Polymerases | 15 Results

Using Polbase tables:


Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).


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