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Results for property: Other Important Residues

Detailed Results for Property

Use this page to examine all the the polymerases and references referring to the property: Other Important Residues.

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Polymerase Kingdom Family Reference Result Context
9egN D141A/D143A Archaeon B Rodriguez AC2000 Cysteine Bridges: Cys428:442, Cys506:509
Klenow fragment Eubacterium A Brautigam CA1999 Eu3+ at exo site
Klenow fragment Eubacterium A Beese LS1993 L361, Q419, R455, F473, Y497, H660, T609, E611, R631, K635, N675, N678
Klenow fragment Eubacterium A Freemont PS1988 L361, Q419, R455, F473, Y497, H660
Klenow fragment Eubacterium A Derbyshire V1988 2 Mn ions show metal A and B positions
KF D424A Eubacterium A Derbyshire V1988 Metal B not bound
KF D355AE357A Eubacterium A Derbyshire V1988 No binding of metals A and B and dNMP
Klenow fragment Eubacterium A Ollis DL1985 dNMP-Zn interacts with D355, E357, T358, L361, D424, F473, Y497, D501
Klenow fragment Eubacterium A Beese LS1991 T358, L361, Q419, R455, F473, Y497, H660
Human Pol beta Eukaryote X Yamtich J2010 Tyr271, Phe272, Asp276, and Asn279 = dNTP binding pocket; Tyr271 = important for both chemistry and dNTP binding, alters steady-state catalytic efficiency
HIV2 RT Virus/Phage RT Ren J2002 Ile-181 and Leu-188 contribute most to NNRTI resistance
Eco Pol I Eubacterium A Kornberg A1964 deoxyadenylate and deoxythymidylate [(AT)3 to (AT)7]
Tth pol X Eubacterium X Nakane S2012 Lys263
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Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

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