Hold tight (but not too tight) to get it right: accurate bypass of an 8-oxoguanine lesion by DNA polymerase beta.

Brieba LG, Ellenberger T
Structure (London, England : 1993) (2003), Volume 11, Page 1
PubMed entry

Abstract:

Crystal structures of DNA polymerase beta encountering an 8-oxoguanine ...
Crystal structures of DNA polymerase beta encountering an 8-oxoguanine lesion show how the polymerase selects an otherwise unfavorable conformation of a damaged template base to enable error-free bypass.

Polymerases:

Human Pol beta

Topics:

Structure and Structure/Function

Status:

new topics/pols set partial results complete validated

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Version:20240424

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