HIV RT

From HIV
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Welcome to the Polymerase Page

This page presents all the information in Polbase for HIV RT.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

HIV RT is a family RT enzyme from HIV.

Selected Properties for HIV RT:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (4) No (1) 8.0e-06-4.7e-03 errors/bp (3) 2.6e-05-3.2e-03 errors/bp (5) 7.5e-05-8.0e-02 errors/bp (4)
Year Authors Title Results by property
N Düzgünes, S Simões, V Slepushkin, E Pretzer, J J Rossi, Erik De Clercq, V P Antao, M L Collins, M C de Lima Enhanced inhibition of HIV-1 replicat...
Paul J Lewi, Marc R De Jonge, Frits F D Daeyaert, Luc Koymans, Maarten H Vinkers, Jan Heeres, Paul A J Janssen, Edward Arnold, Kalyan Das, Art D Clark, Stephen H Hughes, Paul L Boyer, Marie-Pierre P De Béthune, Rudi Pauwels, Koen Andries, Michael Kukla, Donald W Ludovici, Bart De Corte, Robert W Kavash, Chih Y Ho, Paul J Lewis On the detection of multiple-binding ...
P Hafkemeyer, K A Neftel, Ulrich Hübscher HIV-reverse transcriptase and human D...
Erik De Clercq Perspectives for the chemotherapy of ...
Chen Liang, Mark A. Wainberg The role of Tat in HIV-1 replication:...
Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari Structural determinants of HIV-1 reve...
Maria Letizia Barreca, Laura De Luca, Nunzio Iraci, Angela Rao, Stefania Ferro, Giovanni Maga, Alba Chimirri Structure-based pharmacophore identif...
Sherine S L Chan, Janine H Santos, Joel N Meyer, Bhaskar S Mandavilli, Dennis L Cook, Consuelo L McCash, Grace E Kissling, Abraham Nyska, Julie F Foley, Bennett Van Houten, William C Copeland, Vernon E Walker, Kristine L Witt, Jack B Bishop Mitochondrial toxicity in hearts of C...
Mark A. Wainberg, S Bour, R Geleziunas, Z Bentwich [Antiviral strategies in the replicat...
María-Cruz Bonache, Cristina Chamorro, Sonsoles Velázquez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Ana San-Félix N-3 substituted TSAO derivatives as a...
G T Tan, J M Pezzuto, A D Kinghorn, Stephen H Hughes Evaluation of natural products as inh...
Jorge L Martínez-Cajas, Nitika Pant-Pai, Marina B Klein, Mark A. Wainberg Role of genetic diversity amongst HIV...
Erik De Clercq, Robert Snoeck [Current acquisitions in antiviral dr...
Rudi Pauwels, M P de Bethune, Koen Andries, Paul Stoffels, P Janssen, Erik De Clercq Discovery, development and characteri...
Erik De Clercq Perspectives of non-nucleoside revers...
N Gashnikova, O Plyasunova, Y Kiseleva, N Fedyuk, A Pokrovsky In vitro study of resistance-associat...
Erik De Clercq Novel compounds in preclinical/early ...
Erik De Clercq New developments in anti-HIV chemothe...
2013 John E Tavis, Xiaohong Cheng, Yuan Hu, Michael Totten, Feng Cao, Eleftherios Michailidis, Rajeev Aurora, Marvin J Meyers, E Jon Jacobsen, Michael A. Parniak, Stefan G Sarafianos The hepatitis B virus ribonuclease h ...
2013 Mikhail S Novikov, Vladimir T Valuev-Elliston, Denis A Babkov, Maria P Paramonova, Alexander V Ivanov, Sergey A Gavryushov, Anastasia L Khandazhinskaya, Sergey N Kochetkov, Christophe Pannecouque, Graciela Andrei, Robert Snoeck, Jan Balzarini, Katherine L Seley-Radtke N(1),N(3)-disubstituted uracils as no...
2013 Dongyue Li, Peng Zhan, Huiqing Liu, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu Synthesis and biological evaluation o...
2013 Daniel G Kuroda, Joseph David Bauman, J Reddy Challa, Disha Patel, Thomas Troxler, Kalyan Das, Edward Arnold, Robin M Hochstrasser Snapshot of the equilibrium dynamics ...
2013 J-H Lee, Atsuko Hachiya, S-K Shin, J Lee, Hiroyuki Gatanaga, Shinichi Oka, Karen A Kirby, Yee Tsuey Ong, Stefan G Sarafianos, William R Folk, Wangdon Yoo, Sun Pyo Hong, S-O Kim Restriction fragment mass polymorphis...
2013 Kalyan Das, Edward Arnold HIV-1 reverse transcriptase and antiv...
2013 Kalyan Das, Edward Arnold HIV-1 reverse transcriptase and antiv...
2013 Hong-Tao Xu, Susan P Colby-Germinario, Eugene L Asahchop, Maureen Oliveira, Matthew McCallum, Susan M Schader, Yingshan Han, Yudong Quan, Stefan G Sarafianos, Mark A. Wainberg The Effect of Mutations at Position E...
2013 Xuwang Chen, Yuanyuan Li, Shufang Ding, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Huiqing Liu, Xinyong Liu Discovery of Piperidine-Linked Pyridi...
2013 Ravindra K Gupta, DA Van de Vijver, S Manicklal, MA Wainberg Evolving uses of oral reverse transcr...
2013 Mariela Bollini, Kathleen M Frey, José A Cisneros, Krasimir A Spasov, Kalyan Das, Joseph David Bauman, Edward Arnold, Karen S Anderson, William L Jorgensen Extension into the entrance channel o...
2013 A Heredia, CE Davis, MS Reitz, NM Le, MA Wainberg, JS Foulke, LX Wang, RR Redfield Targeting of the Purine Biosynthesis ...
2013 Jan Balzarini, Graciela Andrei, Emanuela Balestra, Dana Huskens, Christophe Vanpouille, Andrea Introini, Sonia Zicari, Sandra Liekens, Robert Snoeck, Antonín Holý, CF Perno, Leonid Margolis, Dominique Schols A Multi-targeted Drug Candidate with ...
2013 Ye Tian, Diwakar Rai, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Huiqing Liu, Xinyong Liu Design, Synthesis, and Biological Eva...
2013 Hai-Qiu Wu, Zi-Hong Yan, Wen-Xue Chen, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Dirk Daelemans, Christophe Pannecouque Towards new C6-rigid S-DABO HIV-1 rev...
2013 Matthew McCallum, Maureen Oliveira, Ruxandra-Ilinca Ibanescu, Victor G Kramer, Daniela D Moisi, Eugene L Asahchop, Bluma G Brenner, Richard Harrigan, Hongtao Xu, Mark A. Wainberg Basis for the Early and Preferential ...
2013 Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd Inhibition of HIV-1 Reverse Transcrip...
2013 Karen A Kirby, Eleftherios Michailidis, Tracy L Fetterly, MA Steinbach, Kamalendra Singh, Bruno Marchand, Maxwell D Leslie, Ariel N Hagedorn, Eiichi N Kodama, Victor E Marquez, Stephen H Hughes, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Effects of 4' - and 2-Substitutions o...
2013 Venkata Ramana Sirivolu, Sanjeev Kumar V Verneka, Tatiana Ilina, Nataliya S Myshakina, Michael A. Parniak, Zhengqiang Wang Clicking 3'-azidothymidine into novel...
2013 Erik De Clercq The Nucleoside Reverse Transcriptase ...
2013 Linda L Dunn, Paul L Boyer, Patrick K Clark, Stephen H Hughes Mutations in HIV-1 reverse transcript...
2013 Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno Marchand, Maxwell D Leslie, Andrew D Huber, Yee Tsuey Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Hypersusceptibility mechanism of Teno...
2013 Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Rita S Schildknecht, Hongtao Xu, Simani Gaseitswe, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg The preferential selection of K65R in...
2013 R S K Vijayan, Edward Arnold, Kalyan Das Molecular dynamics study of HIV-1 RT-...
2013 Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Xinyong Liu Novel piperidinylamino-diarylpyrimidi...
2013 Joseph David Bauman, Disha Patel, Chhaya Dharia, Marc Fromer, Sameer Ahmed, Yulia Volovik Frenkel, J Thomas Eck, William C Ho, Kalyan Das, Aaron J Shatkin, Edward Arnold Detecting allosteric sites of HIV-1 r...
2013 Shiqiong Yang, Christophe Pannecouque, Dirk Daelemans, Xiao-Dong Ma, Yang Liu, Fen-Er Chen, Erik De Clercq Molecular design, synthesis and biolo...
2012 Christal D Sohl, Rajesh Kasiviswanathan, Jiae Kim, Ugo Pradere, Raymond F Schinazi, William C Copeland, Hiroyuki Mitsuya, Masanori Baba, Karen S Anderson Balancing Antiviral Potency and Host ...
2012 Barry C Johnson, Gary T Pauly, Ganesha Rai, Disha Patel, Joseph David Bauman, Heather L Baker, Kalyan Das, Joel P Schneider, David J Maloney, Edward Arnold, Craig J Thomas, Stephen H Hughes A comparison of the ability of rilpiv...
2012 Martin T Christen, Lakshmi Menon, Nataliya S Myshakina, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima Structural basis of the allosteric in...
2012 Victor G Kramer, Susan M Schader, Maureen Oliveira, Susan P Colby-Germinario, Daniel A Donahue, Diane N Singhroy, Randy Tressler, Richard D Sloan, Mark A. Wainberg Maraviroc and other HIV-1 entry inhib...
2012 Kalyan Das, Sergio E Martinez, Joseph David Bauman, Edward Arnold HIV-1 reverse transcriptase complex w...
2012 Karen A Kirby, Bruno Marchand, Yee Tsuey Ong, Tanyaradzwa P Ndongwe, Atsuko Hachiya, Eleftherios Michailidis, Maxwell D Leslie, Daniel V Sietsema, Tracy L Fetterly, Christopher A Dorst, Kamalendra Singh, Zhengqiang Wang, Michael A. Parniak, Stefan G Sarafianos Structural and Inhibition Studies of ...
2012 Peng Zhan, Xincang Li, Zhongjie Li, Xuwang Chen, Ye Tian, Wenmin Chen, Xinyong Liu, Christophe Pannecouque, Erik De Clercq Structure-based bioisosterism design,...
2012 Xuwang Chen, Peng Zhan, Xin Liu, Ziheng Cheng, Caicai Meng, Siyuan Shao, Christophe Pannecouque, Erik De Clercq, Xinyong Liu Design, synthesis, anti-HIV evaluatio...
2012 Atsuko Hachiya, Bruno Marchand, Karen A Kirby, Eleftherios Michailidis, Xiongying Tu, Krzysztof Palczewski, Yee Tsuey Ong, Zhongjie Li, Daniel T Griffin, Matthew M Schuckmann, Junko Tanuma, Shinichi Oka, Kamalendra Singh, Eiichi N Kodama, Stefan G Sarafianos HIV-1 reverse transcriptase (RT) poly...
2012 Tatiana Ilina, Krystal Labarge, Stefan G Sarafianos, Rieko Ishima, Michael A. Parniak Inhibitors of HIV-1 Reverse Transcrip...
2012 Ye Tian, Peng Zhan, Diwakar Rai, Jiyan Zhang, Erik De Clercq, Xinyong Liu Recent advances in the research of 2,...
2012 Eleftherios Michailidis, Kamlendra Singh, Emily M Ryan, Atsuko Hachiya, Yee Tsuey Ong, Karen A Kirby, Bruno Marchand, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Effect of translocation defective rev...
2012 Sergio R Ribone, Volker Leen, Marcela Madrid, Wim Dehaen, Dirk Daelemans, Christophe Pannecouque, Margarita C Briñón Synthesis, biological evaluation and ...
2012 Shiqiong Yang, Fen-Er Chen, Erik De Clercq Dihydro-alkoxyl-benzyl-oxopyrimidine ...
2012 Dongyue Li, Peng Zhan, Erik De Clercq, Xinyong Liu Strategies for the design of HIV-1 no...
2012 Wenwen Chen, Peng Zhan, Erik De Clercq, Xinyong Liu Recent progress in small molecule CCR...
2012 Zhongjie Li, Yuan Cao, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu Arylazolylthioacetanilide. Part 11: D...
2012 Shuang-Xi Gu, Zhi-Ming Li, Xiao-Dong Ma, Shi-Qiong Yang, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Chiral resolution, absolute configura...
2012 Eva-María Priego, Anna Karlsson, Federico Gago, María-José Camarasa, Jan Balzarini, María-Jesús Pérez-Pérez Recent advances in thymidine kinase 2...
2012 Xuwang Chen, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu Synthesis and biological evaluation o...
2012 Christophe Vanpouille, Andrea Lisco, Andrea Introini, Jean-Charles Grivel, Arshi Munawwar, Melanie Merbah, Raymond F Schinazi, Marco Derudas, Christopher McGuigan, Jan Balzarini, Leonid Margolis Exploiting the anti-HIV-1 activity of...
2012 Peng Zhan, Wenmin Chen, Zhongjie Li, Xincang Li, Xuwang Chen, Ye Tian, Christophe Pannecouque, Erik De Clercq, Xinyong Liu Discovery of novel 2-(3-(2-chlorophen...
2012 Xincang Li, Peng Zhan, Erik De Clercq, Xinyong Liu The HIV-1 Non-Nucleoside Reverse Tran...
2012 K O François, Jan Balzarini Potential of carbohydrate-binding age...
2012 Kamalendra Singh, Bruno Marchand, Devendra K Rai, Bechan Sharma, Eleftherios Michailidis, Emily M Ryan, Kayla B Matzek, Maxwell D Leslie, Ariel N Hagedorn, Zhongjie Li, Pieter R Norden, Atsuko Hachiya, Michael A. Parniak, Hong-Tao Xu, Mark A. Wainberg, Stefan G Sarafianos Biochemical Mechanism of HIV-1 Resist...
2012 Wei-Shau Hu, Stephen H Hughes HIV-1 Reverse Transcription.
2012 Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd DNA Polymerase β Gap-filling Transles...
2012 Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valeria Famiglini, Sandro Cosconati, Giovanni Maga, Alberta Samuele, Emmanuel Gonzales, B Clotet, Dominique Schols, Jose Este, Ettore Novellino, Romano Silvestri New Nitrogen Containing Substituents ...
2012 Changfu Yang, Shuyuan Liu, Taisong Zhang, Yaping Hou, Xiaoli Liu, Yun Gao, Guang Yang, Zhen Wang, Huayun Chen, Ming Li, Zhenyu Zhu Transmitted antiretroviral drug resis...
2012 Paul L Boyer, Patrick K Clark, Stephen H Hughes HIV-1 and HIV-2 Reverse Transcriptase...
2012 Dante Rotili, Alberta Samuele, Domenico Tarantino, Rino Ragno, Ira Musmuca, Flavio Ballante, Giorgia Botta, Ludovica Morera, Marco Pierini, Roberto Cirilli, Maxim B Nawrozkij, Emmanuel Gonzalez, B Clotet, Marino Artico, José A Esté, Giovanni Maga, Antonello Mai 2-(Alkyl/Aryl)Amino-6-Benzylpyrimidin...
2012 Marco Radi, Mafalda Pagano, Luigi Franchi, Daniele Castagnolo, Silvia Schenone, Gianni Casaluce, Claudio Zamperini, Elena Dreassi, Giovanni Maga, Alberta Samuele, Encarna Gonzalo, B Clotet, José A Esté, Maurizio Botta Synthesis, Biological Activity, and A...
2012 Serdal Kirmizialtin, Virginia Nguyen, Kenneth A Johnson, Ron Elber How conformational dynamics of DNA po...
2011 Dimitrios Coutsinos, Cédric F Invernizzi, Daniela D Moisi, Maureen Oliveira, Jorge L Martinez-Cajas, Bluma G Brenner, Mark A. Wainberg A template-dependent dislocation mech...
2011 Mark A. Wainberg, Daniela D Moisi, Maureen Oliveira, Thomas D'Aquin Toni, Bluma G Brenner Transmission dynamics of the M184V dr...
2011 Hong-Tao Xu, Eugene L Asahchop, Maureen Oliveira, Peter K Quashie, Yudong Quan, Bluma G Brenner, Mark A. Wainberg Compensation by the E138K mutation in...
2011 Kalyan Das, Joseph David Bauman, Angela S Rim, Chhaya Dharia, Arthur D Clark, María-José Camarasa, Jan Balzarini, Edward Arnold Crystal structure of tert-butyldimeth...
2011 Matthias Götte Initiation of HIV reverse transcripti...
2011 Anick Auger, Greg L Beilhartz, Siqi Zhu, Elizabeth Cauchon, Jean-Pierre Falgueyret, Jay A Grobler, Maryam Ehteshami, Matthias Götte, Roman A Melnyk Impact of primer-induced conformation...
2011 Chandravanu Dash, Yousef Ahmadibeni, Michael J Hanley, Jui Pandhare, Mathias Gotte, Stuart F J Le Grice, Keykavous Parang Inhibition of multi-drug resistant HI...
2011 Brian J Scarth, Kirsten L White, James M Chen, Eric B Lansdon, S Swaminathan, Michael D Miller, Matthias Götte Mechanism of resistance to GS-9148 co...
2011 Brian J Scarth, Suzanne McCormick, Matthias Götte Effects of mutations F61A and A62V in...
2011 O Jegede, A Khodyakova, M Chernov, J Weber, L Menéndez-Arias, A Gudkov, ME Quiñones-Mateu Identification of low-molecular weigh...
2011 Erik De Clercq A 40-year journey in search of select...
2011 Xuwang Chen, Peng Zhan, Dongyue Li, Erik De Clercq, Xinyong Liu Recent advances in DAPYs and related ...
2011 Mingyan Yu, Zhongjie Li, Shuai Liu, Erkang Fan, Christophe Pannecouque, Erik De Clercq, Xinyong Liu Synthesis and biological evaluation o...
2011 Peng Zhan, Xuwang Chen, Dongyue Li, Zengjun Fang, Erik De Clercq, Xinyong Liu HIV-1 NNRTIs: Structural diversity, p...
2011 Jing Zhang, Peng Zhan, Jingde Wu, Zhongjie Li, Yan Jiang, Weiying Ge, Christophe Pannecouque, Erik De Clercq, Xinyong Liu Synthesis and biological evaluation o...
2011 Claudette S Satchell, Jane A O'Halloran, Aoife G Cotter, Aaron J Peace, Eileen F O'Connor, Anthony F Tedesco, Eoin R Feeney, John S Lambert, Gerard J Sheehan, Dermot Kenny, Patrick W G Mallon Increased Platelet Reactivity in HIV-...
2011 Allison K Delong, Mingham Wu, Diane Bennett, Neil Parkin, Zhijin Wu, Joseph W Hogan, Rami Kantor Sequence Quality Analysis Tool (SQUAT...
2011 Brian D Herman, Raymond F Schinazi, Hong-Wang Zhang, James H Nettles, Richard Stanton, Mervi Detorio, Aleksandr Obikhod, Ugo Pradère, Steven J Coats, John W Mellors, Nicolas Sluis-Cremer Substrate mimicry: HIV-1 reverse tran...
2011 Jing-Rong Ye, Lei Guo, Hong-Yan Lu, Ruo-Lei Xin, Yi Zeng [Genotypic resistance mutations to an...
2011 María-Cruz Bonache, Alessandra Cordeiro, Ernesto Quesada, Els Vanstreels, Dirk Daelemans, María-José Camarasa, Jan Balzarini, Ana San-Félix Selective inhibition of Human Immunod...
2011 Mikhail S Novikov, Olga N Ivanova, Alexander V Ivanov, Alexander A Ozerov, Vladimir T Valuev-Elliston, Kartik Temburnikar, Galina V Gurskaya, Sergey N Kochetkov, Christophe Pannecouque, Jan Balzarini, Katherine L Seley-Radtke 1-[2-(2-Benzoyl- and 2-benzylphenoxy)...
2011 Xiao-Dong Ma, Shi-Qiong Yang, Shuang-Xi Gu, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Synthesis and anti-HIV activity of ar...
2011 Graciela Andrei, Andrea Lisco, Christophe Vanpouille, Andrea Introini, Emanuela Balestra, Joost van den Oord, Tomas Cihlar, CF Perno, Robert Snoeck, Leonid Margolis, Jan Balzarini Topical tenofovir, a microbicide effe...
2011 Han-Ping Li, Wei Guo, Yong-Jian Liu, Zuo-Yi Bao, Lin Li, Dao-Min Zhuang, Si-Yang Liu, Zhengqiang Wang, Xiao-Lin Wang, Jing-Yun Li [Screening program on novel drug resi...
2011 Tao Dong, Yongqing Zhang, Ke Yi Xu, Huiping Yan, Ian James, Yanchun Peng, Marie-Eve Blais, Silvana Gaudieri, Xinyue Chen, Wenhui Lun, Hao Wu, Wen Yan Qu, Tim Rostron, Ning Li, Yu Mao, Simon Mallal, Xiaoning Xu, Andrew McMichael, Mina John, Sarah L Rowland-Jones Extensive HLA-driven viral diversity ...
2011 Qingguo Gong, Lakshmi Menon, Tatiana Ilina, Lena G Miller, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima Interaction of HIV-1 reverse transcri...
2011 Matthew W Kellinger, Kenneth A Johnson Role of induced fit in limiting discr...
2011 Zhinan Jin, Jerome Deval, Kenneth A Johnson, David C Swinney Characterization of the elongation co...
2011 Stefania Butini, Sandra Gemma, Margherita Brindisi, Giuseppe Borrelli, Isabella Fiorini, Alberta Samuele, Aristotele Karytinos, Marcella Facchini, Andrea Lossani, Samantha Zanoli, Giuseppe Campiani, Ettore Novellino, Federico Focher, Giovanni Maga Enantioselective binding of second ge...
2011 Dante Rotili, Domenico Tarantino, Marino Artico, Maxim B Nawrozkij, Emmanuel Gonzalez-Ortega, B Clotet, Alberta Samuele, José A Esté, Giovanni Maga, Antonello Mai Diarylpyrimidine-dihydrobenzyloxopyri...
2011 Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valerio Gatti, Giovanni Maga, Alberta Samuele, Christophe Pannecouque, Dominique Schols, Jan Balzarini, Ettore Novellino, Romano Silvestri Indolylarylsulfones as HIV-1 non-nucl...
2011 Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang N-3 Hydroxylation of Pyrimidine-2,4-d...
2011 Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang 6-Benzoyl-3-hydroxypyrimidine-2,4-dio...
2011 Jing Tang, Kasthuraiah Maddali, Mathieu Metifiot, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang 3-Hydroxypyrimidine-2,4-diones as an ...
2011 Yuan Yuan, Hui Xing, Xiao-Yu Wang, Chun-hua Liu, Li-Ting Yang, Ben-Feng Zheng, Xia Wang, Yu-Hua Ruan, Zhe Wang, Hong-wei Liu, Yi-ming Shao [The prevalence of HIV-1 drug resista...
2011 Peibin Zeng, Jingxing Wang, Yi Huang, Xiaoming Guo, Jinming Li, Guoxin Wen, Tonghan Yang, Zhongqiao Yun, Miao He, Yu Liu, Yuzhe Yuan, Jane Schulmann, Simone Glynn, Paul Ness, J Brooks Jackson, Hua Shan The human immunodeficiency virus-1 ge...
2011 Alberta Samuele, Sara Bisi, Alexandra Kataropoulou, Giuseppe La Regina, Francesco Piscitelli, Valerio Gatti, Romano Silvestri, Giovanni Maga Mechanism of interaction of novel ind...
2011 Tanyaradzwa P Ndongwe, Adeyemi O Adedeji, Eleftherios Michailidis, Yee Tsuey Ong, Atsuko Hachiya, Bruno Marchand, Emily M Ryan, Devendra K Rai, Karen A Kirby, Angela S Whatley, Donald H Burke, Marc Johnson, Shilei Ding, Yi-Min Zheng, Shan-Lu Liu, Ei-Ichi Kodama, Krista A Delviks-Frankenberry, Vinay K Pathak, Hiroyuki Mitsuya, Michael A. Parniak, Kamalendra Singh, Stefan G Sarafianos Biochemical, inhibition and inhibitor...
2011 Mark A Ditzler, Debojit Bose, Nikolozi Shkriabai, Bruno Marchand, Stefan G Sarafianos, Mamuka Kvaratskhelia, Donald H Burke Broad-spectrum aptamer inhibitors of ...
2011 Karen A Kirby, Kamalendra Singh, Eleftherios Michailidis, Bruno Marchand, Eiichi N Kodama, Noriyuki Ashida, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos The sugar ring conformation of 4'-eth...
2011 Atsuko Hachiya, Eiichi N Kodama, Matthew M Schuckmann, Karen A Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G Sarafianos K70Q adds high-level tenofovir resist...
2011 Joseph David Bauman, Disha Patel, Edward Arnold Fragment Screening and HIV Therapeutics.
2011 Anthony K Felts, Krystal Labarge, Joseph David Bauman, Dishaben V Patel, Daniel M Himmel, Edward Arnold, Michael A. Parniak, Ronald M Levy Identification of alternative binding...
2011 Suhman Chung, Daniel M Himmel, Jian-Kang Jiang, Krzysztof Wojtak, Joseph David Bauman, Jason W Rausch, Jennifer A Wilson, John A Beutler, Craig J Thomas, Edward Arnold, Stuart F J Le Grice Synthesis, activity, and structural a...
2011 Suhman Chung, Jennifer T Miller, Barry C Johnson, Stephen H Hughes, Stuart F J Le Grice Mutagenesis of the human immunodefici...
2011 Eugene L Asahchop, Maureen Oliveira, Mark A. Wainberg, Bluma G Brenner, Daniela D Moisi, Thomas D'Aquin Toni, Cecile L Tremblay Characterization of the E138K resista...
2011 Bluma G Brenner, Matthew Lowe, Daniela D Moisi, Isabelle Hardy, Simon Gagnon, Hugues Charest, Jean Guy Baril, Mark A. Wainberg, Michel Roger Subtype diversity associated with the...
2010 Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Bluma G Brenner, Mark A. Wainberg Factors affecting template usage in t...
2010 Guido van Marle, Deirdre L Church, Kali D Nunweiler, Kris Cannon, Mark A. Wainberg, M John Gill Higher levels of Zidovudine resistant...
2010 Hong-Tao Xu, Maureen Oliveira, Yudong Quan, Tamara Bar-Magen, Mark A. Wainberg Differential impact of the HIV-1 non-...
2010 Wujie Li, Mou Cao, Lu Pei, Xiaomei Ling, Bingchao Li, Zhenjun Yang Study on steady-state kinetics of nuc... RT,All properties
2010 Erik De Clercq Antiretroviral drugs.
2010 John C Martin, Michael J M Hitchcock, Erik De Clercq, William H Prusoff Early nucleoside reverse transcriptas...
2010 Erik De Clercq In search of a selective therapy of v...
2010 Zhao-Sen Zeng, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq Lead optimization of diarylpyrimidine...
2010 Yong-Hong Liang, Qiu-Qin He, Zhao-Sen Zeng, Zhi-Qian Liu, Xiao-Qing Feng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq Synthesis and anti-HIV activity of 2-...
2010 Romuald Corbau, Julie Mori, Chris Phillips, Lesley Fishburn, Alex Martin, Charles Mowbray, Wendy Panton, Caroline Smith-Burchnell, Adele Thornberry, Heather Ringrose, Thorsten Knöchel, Steve Irving, Mike Westby, Anthony Wood, Manos Perros Lersivirine: a Non-Nucleoside Reverse... RT,All properties
2010 Zhao-Sen Zeng, Qiu-Qin He, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Hybrid diarylbenzopyrimidine non-nucl...
2010 Alberta Samuele, Emmanuele Crespan, Samanta Vitellaro, Anna-Maria Monforte, Patrizia Logoteta, Alba Chimirri, Giovanni Maga Slow binding-tight binding interactio...
2010 Anna-Maria Monforte, Patrizia Logoteta, Laura De Luca, Nunzio Iraci, Stefania Ferro, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri Novel 1,3-dihydro-benzimidazol-2-ones...
2010 Matthias Götte, Jason W Rausch, Bruno Marchand, Stefan G Sarafianos, Stuart F J Le Grice Reverse transcriptase in motion: conf...
2010 Viktor von Wyl, Maryam Ehteshami, Jori Symons, Philippe Bürgisser, Monique Nijhuis, Lisa M Demeter, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard Epidemiological and biological eviden...
2010 Greg L Beilhartz, Matthias Götte HIV-1 Ribonuclease H: Structure, Cata...
2010 Yuhua Ruan, Hui Xing, Xia Wang, Heng Tang, Zhengqiang Wang, Hongwei Liu, Bin Su, Jianjun Wu, Hanping Li, Lingjie Liao, Jinming Li, Julia Wei Wu, Yiming Shao Virologic outcomes of first-line HAAR...
2010 Zhengqiang Wang, Jing Tang, Christine E Salomon, Christine D Dreis, Robert Vince Pharmacophore and structure-activity ...
2010 Martin Di Grandi, Matthew Olson, Amar S Prashad, Geraldine Bebernitz, Amara Luckay, Stanley Mullen, Yongbo Hu, Girija Krishnamurthy, Keith Pitts, John O'Connell Small molecule inhibitors of HIV RT R...
2010 Li-Jia Xu, Zong-Gen Peng, Hong-Shan Chen, Jie Wang, Pei-Gen Xiao Bioactive triterpenoids from Kadsura ...
2010 H Nina Kim, Jing Wang, James Hughes, Robert Coombs, Jorge Sanchez, Stewart Reid, Sinead Delany-Moretlwe, Frances Cowan, Jonathan Fuchs, Susan H Eshleman, Leila Khaki, Moira A McMahon, Robert F Siliciano, Anna Wald, Connie Celum Effect of acyclovir on HIV-1 set poin...
2010 Hua-Poo Su, Youwei Yan, G Sridhar Prasad, Robert F Smith, Christopher L Daniels, Pravien D Abeywickrema, John C Reid, H Marie Loughran, Maria Kornienko, Sujata Sharma, Jay A Grobler, Bei Xu, Vinod Sardana, Timothy J Allison, Peter D Williams, Paul L Darke, Daria J Hazuda, Sanjeev Munshi Structural basis for the inhibition o... RT,RNase H,All properties
2010 Mia J Biondi, Greg L Beilhartz, Suzanne McCormick, Matthias Götte N348I in HIV-1 reverse transcriptase ...
2010 Pankaj R Daga, Jinsong Duan, Robert J Doerksen Computational model of hepatitis B vi...
2010 Suhman Chung, Michaela Wendeler, Jason W Rausch, Greg L Beilhartz, Matthias Gotte, Barry R O'Keefe, Alun Bermingham, John A Beutler, Shixin Liu, Xiaowei Zhuang, Stuart F J Le Grice Structure-activity analysis of vinylo...
2010 Guozhi Tang, Denis J Kertesz, Minmin Yang, Xianfeng Lin, Zhengqiang Wang, Wentao Li, Zongxing Qiu, Junli Chen, Jianghua Mei, Li Chen, Taraneh Mirzadegan, Seth F Harris, Armando G Villaseñor, Jennifer Fretland, William L Fitch, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp Exploration of piperidine-4-yl-aminop...
2010 Giovanni Maga, Marco Radi, Marie-Aline Gerard, Maurizio Botta, Eric Ennifar HIV-1 RT Inhibitors with a Novel Mech...
2010 Brian D Herman, Ivan Votruba, Antonin Holy, Nicolas Sluis-Cremer, Jan Balzarini The acyclic 2,4-diaminopyrimidine nuc...
2010 Michael E Abram, Andrea L Ferris, Wei Shao, W Gregory Alvord, Stephen H Hughes Nature, position, and frequency of mu...
2010 Hong-Tao Xu, Yudong Quan, Eugene L Asahchop, Maureen Oliveira, Daniella Moisi, Mark A. Wainberg Comparative biochemical analysis of r...
2010 Daniel A Donahue, Richard D Sloan, Björn D Kuhl, Tamara Bar-Magen, Susan M Schader, Mark A. Wainberg Stage-dependent inhibition of HIV-1 r...
2010 Matthew M Schuckmann, Bruno Marchand, Atsuko Hachiya, Eiichi N Kodama, Karen A Kirby, Kamalendra Singh, Stefan G Sarafianos The N348I mutation at the connection ...
2010 Séverine Freisz, Guillaume Bec, Marco Radi, Philippe Wolff, Emmanuele Crespan, Lucilla Angeli, Philippe Dumas, Giovanni Maga, Maurizio Botta, Eric Ennifar Crystal Structure of HIV-1 Reverse Tr... RT,All properties
2010 Xiongying Tu, Kalyan Das, Qianwei Han, Joseph David Bauman, Arthur D Clark, Xiaorong Hou, Yulia Volovik Frenkel, Barbara L Gaffney, Roger A Jones, Paul L Boyer, Stephen H Hughes, Stefan G Sarafianos, Edward Arnold Structural basis of HIV-1 resistance ...
2010 Matthew W Kellinger, Kenneth A Johnson Nucleotide-dependent conformational c... RT,All properties
2010 Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq 1,2,3-thiadiazole thioacetanilides. P...
2010 Michael L Mitchell, Jong Chan Son, Hongyan Guo, Yun-A Im, Eun Jung Cho, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Doris Graupe, Gerry Rhodes, Gong-Xin He, Romas Geleziunas, Lianhong Xu, Choung U Kim N1-Alkyl pyrimidinediones as non-nucl... RT,All properties
2010 Michael L Mitchell, Jong Chan Son, Ill Young Lee, Chong-Kyo Lee, Hae Soo Kim, Hongyan Guo, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Gene Eisenberg, Romas Geleziunas, Lianhong Xu, Choung U Kim N1-Heterocyclic pyrimidinediones as n... RT,All properties
2010 Eric B Lansdon, Katherine M Brendza, Magdeleine Hung, Ruth Wang, Susmith Mukund, Debi Jin, Gabriel Birkus, Nilima Kutty, Xiaohong Liu Crystal structures of HIV-1 reverse t... RT,Associated condition,All properties
2010 Eric B Lansdon, Dharmaraj Samuel, Leanna Lagpacan, Katherine M Brendza, Kirsten L White, Magdeleine Hung, Xiaohong Liu, Constantine G Boojamra, Richard L Mackman, Tomas Cihlar, Adrian S Ray, Mary E McGrath, S Swaminathan Visualizing the molecular interaction... RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Polymerase Catalytic Residue Amino Acids,Residues Involved in Catalysis of RNase H,Incorporation of non-standard nucleotides,All properties
2010 Denis J Kertesz, Christine Brotherton-Pleiss, Minmin Yang, Zhengqiang Wang, Xianfeng Lin, Zongxing Qiu, Donald R Hirschfeld, Shelley K Gleason, Taraneh Mirzadegan, Pete W Dunten, Seth F Harris, Armando G Villaseñor, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp Discovery of piperidin-4-yl-aminopyri... RT,All properties
2010 Viktor von Wyl, Maryam Ehteshami, Lisa M Demeter, Philippe Bürgisser, Monique Nijhuis, Jori Symons, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard HIV-1 reverse transcriptase connectio...
2010 Michael E Abram, Stefan G Sarafianos, Michael A. Parniak The mutation T477A in HIV-1 reverse t...
2009 Thorsten A Kirschberg, Mini Balakrishnan, Neil H Squires, Tiffany Barnes, Katherine M Brendza, Xiaowu Chen, Eugene J Eisenberg, Weili Jin, Nilima Kutty, Stephanie Leavitt, Albert C Liclican, Qi Liu, Xiaohong Liu, John Mak, Jason K Perry, Michael Wang, William J Watkins, Eric B Lansdon RNase H active site inhibitors of hum...
2009 Egor P Tchesnokov, Aleksandr Obikhod, Ivana Massud, Andrea Lisco, Christophe Vanpouille, Beda Brichacek, Jan Balzarini, Christopher McGuigan, Marco Derudas, Leonid Margolis, Raymond F Schinazi, Matthias Götte Mechanisms associated with HIV-1 resi...
2009 Paul L Boyer, B Christie Vu, Zandrea Ambrose, John G Julias, Svenja Warnecke, Chenzhong Liao, Chris Meier, Victor E Marquez, Stephen H Hughes The nucleoside analogue D-carba T blo...
2009 Greg L Beilhartz, Michaela Wendeler, Noel S Baichoo, Jason W Rausch, Stuart F J Le Grice, Matthias Götte HIV-1 reverse transcriptase can simul...
2009 Linda L Dunn, Mary Jane McWilliams, Kalyan Das, Edward Arnold, Stephen H Hughes Mutations in the thumb allow human im...
2009 Kristina A Paris, Omar Haq, Anthony K Felts, Kalyan Das, Edward Arnold, Ronald M Levy Conformational landscape of the human...
2009 Stefan G Sarafianos, Bruno Marchand, Kalyan Das, Daniel M Himmel, Michael A. Parniak, Stephen H Hughes, Edward Arnold Structure and function of HIV-1 rever...
2009 Kazuki Izumi, Eiichi N Kodama, Kazuya Shimura, Yasuko Sakagami, Kentaro Watanabe, Saori Ito, Tsuyoshi Watabe, Yukihiro Terakawa, Hiroki Nishikawa, Stefan G Sarafianos, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka Design of peptide-based inhibitors fo...
2009 Takeshi Naito, Kazuki Izumi, Eiichi N Kodama, Yasuko Sakagami, Keiko Kajiwara, Hiroki Nishikawa, Kentaro Watanabe, Stefan G Sarafianos, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka SC29EK, a peptide fusion inhibitor wi...
2009 Atsuko Hachiya, Kazuki Shimane, Stefan G Sarafianos, Eiichi N Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi, Shinichi Oka Clinical relevance of substitutions i...
2009 Matthew D Cullen, William C Ho, Joseph David Bauman, Kalyan Das, Edward Arnold, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Crystallographic study of a novel sub... RT,All properties
2009 Dai-Shi Su, John J Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J Felock, Meiqing Lu, Ming-Tain Lai, Sinoeun Touch, Gregory Moyer, Daniel J Distefano, Jessica A Flynn, Yuexia Liang, Rosa Sanchez, Sridhar Prasad, Youwei Yan, Rebecca A Perlow-Poehnelt, Maricel Torrent, Michael D Miller, Joe P Vacca, Theresa M Williams, Neville J Anthony Substituted tetrahydroquinolines as p... RT,All properties
2009 Young-Sam Lee, W Dexter Kennedy, Y Whitney Yin Structural insight into processive hu...
2009 Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg Signature nucleotide polymorphisms at...
2009 Yudong Quan, Chen Liang, Bluma G Brenner, Mark A. Wainberg Multidrug-resistant variants of HIV t...
2009 Susan P Colby-Germinario, Adan Rios, Jorge Quesada, Dallas Anderson, Allan L Goldstein, Theresa Fossum, Mark A. Wainberg HIV inactivation by cross-linking of ...
2009 Hongtao Xu, Yudong Quan, Bluma G Brenner, Tamara Bar-Magen, Maureen Oliveira, Susan M Schader, Mark A. Wainberg Human immunodeficiency virus type 1 r...
2009 Dan Turner, Eduardo Shahar, Eugene Katchman, Eynat Kedem, Natasha Matus, Michal Katzir, Gamal Hassoun, Shimon Pollack, Rivka Kessner, Mark A. Wainberg, Boaz Avidor Prevalence of the K65R resistance rev...
2009 Daniel M Himmel, Karen A Maegley, Tom A Pauly, Joseph David Bauman, Kalyan Das, Chhaya Dharia, Arthur D Clark, Kevin Ryan, Michael J Hickey, Robert A Love, Stephen H Hughes, Simon Bergqvist, Edward Arnold Structure of HIV-1 reverse transcript... RT,RNase H,All properties
2009 Kalyan Das, Rajiv P Bandwar, Kirsten L White, Joy Y Feng, Stefan G Sarafianos, Steven Tuske, Xiongying Tu, Arthur D Clark, Paul L Boyer, Xiaorong Hou, Barbara L Gaffney, Roger A Jones, Michael D Miller, Stephen H Hughes, Edward Arnold Structural basis for the role of the ... RT,All properties
2009 Hironori Nishitsuji, Takaya Hayashi, Tomosaburo Takahashi, Masashi Miyano, Mari Kannagi, Takao Masuda Augmentation of reverse transcription...
2009 L Menéndez-Arias Mutation Rates and Intrinsic Fidelity... Frameshift Error Rate,All properties
2009 Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Daniela D Moisi, Maureen Oliveira, Bluma G Brenner, Mark A. Wainberg Template usage is responsible for the...
2009 Anders Vahlne A historical reflection on the discov...
2009 Alberta Samuele, Alexandra Kataropoulou, Marco Viola, Samantha Zanoli, Giuseppe La Regina, Francesco Piscitelli, Romano Silvestri, Giovanni Maga Non-nucleoside HIV-1 reverse transcri...
2009 Marco Radi, Giovanni Maga, Maddalena Alongi, Lucilla Angeli, Alberta Samuele, Samantha Zanoli, Luca Bellucci, Andrea Tafi, Gianni Casaluce, Gianluca Giorgi, Mercedes Armand-Ugon, Emmanuel Gonzalez, José A Esté, Mireille Baltzinger, Guillaume Bec, Philippe Dumas, Eric Ennifar, Maurizio Botta Discovery of chiral cyclopropyl dihyd...
2009 MC Puertas, MJ Buzón, A Artese, S Alcaro, L Menéndez-Arias, CF Perno, B Clotet, F Ceccherini-Silberstein, J Martinez-Picado Effect of the human immunodeficiency ...
2009 Stefania Butini, Margherita Brindisi, Sandro Cosconati, Luciana Marinelli, Giuseppe Borrelli, Salvatore Sanna Coccone, Anna Ramunno, Giuseppe Campiani, Ettore Novellino, Samantha Zanoli, Alberta Samuele, Gianluca Giorgi, Alberto Bergamini, Michela Di Mattia, Silvana Lalli, Bruno Galletti, Sandra Gemma, Giovanni Maga Specific targeting of highly conserve...
2009 Francesco Piscitelli, Antonio Coluccia, Andrea Brancale, Giuseppe La Regina, Anna Sansone, Cesare Giordano, Jan Balzarini, Giovanni Maga, Samantha Zanoli, Alberta Samuele, Roberto Cirilli, Francesco La Torre, Antonio Lavecchia, Ettore Novellino, Romano Silvestri Indolylarylsulfones bearing natural a...
2009 Alexandra Kataropoulou, Chiara Bovolenta, Amalia Belfiore, Sonia Trabatti, Anna Garbelli, Simona Porcellini, Rossella Lupo, Giovanni Maga Mutational analysis of the HIV-1 auxi...
2009 Anna-Maria Monforte, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri Design, synthesis, and structure-acti...
2009 Takuma Kimura, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Eiji Ohashi, Haruo Ohmori, Chikahide Masutani, Fumio Hanaoka, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Penicilliols A and B, novel inhibitor...
2009 Yoshiyuki Mizushina, Hirohisa Motoshima, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Ken Hirano, Fumio Sugawara, Hiromi Yoshida 3-O-methylfunicone, a selective inhib...
2009 Bo-Liang Deng, Yaofeng Zhao, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Synthesis of alkenyldiarylmethanes (A...
2009 Erik De Clercq Anti-HIV drugs: 25 compounds approved...
2009 Dharmesh H Mahajan, Christophe Pannecouque, Erik De Clercq, Kishor H Chikhalia Synthesis and studies of new 2-(couma...
2009 Peng Zhan, Zhongjie Li, Xinyong Liu, Erik De Clercq Sulfanyltriazole/tetrazoles: a promis...
2009 Peng Zhan, Xinyong Liu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq Synthesis and anti-HIV activity evalu...
2009 Peng Zhan, Xinyong Liu, Zengjun Fang, Christophe Pannecouque, Erik De Clercq 1,2,3-Selenadiazole thioacetanilides:...
2009 Peng Zhan, Xinyong Liu, Zhongjie Li, Christophe Pannecouque, Erik De Clercq Design strategies of novel NNRTIs to ...
2009 Erik De Clercq A new drug combination therapy for tr...
2009 Franck Chiappini, Elina Teicher, Raphaël Saffroy, Brigitte Debuire, Daniel Vittecoq, Antoinette Lemoine Relationship between polymerase gamma...
2009 Marco Derudas, Davide Carta, Andrea Brancale, Christophe Vanpouille, Andrea Lisco, Leonid Margolis, Jan Balzarini, Christopher McGuigan The application of phosphoramidate pr...
2009 Yong-Hong Liang, Xiao-Qing Feng, Zhao-Sen Zeng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq Design, synthesis, and SAR of naphthy...
2009 Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque Non-nucleoside HIV-1 reverse transcri...
2009 Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Synthesis and in vitro anti-HIV evalu...
2009 Xuexiang Zhang, Xueyan Jiang, Hongzhou Lu, Fang Shen, Jiangrong Wang Dyslipidaemia and Intima-Media Thickn...
2009 Peng Zhan, Xinyong Liu, Junjie Zhu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq Synthesis and biological evaluation o...
2008 Thomas J Tucker, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, John C Reid, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan Discovery of 3-{5-[(6-amino-1H-pyrazo... RT,All properties
2008 Thomas J Tucker, Sandeep Saggar, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan The design and synthesis of diaryl et... RT,All properties
2008 Andrea Lisco, Christophe Vanpouille, Egor P Tchesnokov, Jean-Charles Grivel, Angélique Biancotto, Beda Brichacek, Julie Elliott, Emilie Fromentin, Robin Shattock, Peter Anton, Robert Gorelick, Jan Balzarini, Christopher McGuigan, Marco Derudas, Matthias Götte, Raymond F Schinazi, Leonid Margolis Acyclovir is activated into a HIV-1 r... RT,All properties
2008 Julie Lemay, Priscilla Maidou-Peindara, Reynel Cancio, Eric Ennifar, Gaël Coadou, Giovanni Maga, Jean-Christophe Rain, Richard Benarous, Lang Xia Liu AKAP149 binds to HIV-1 reverse transc...
2008 Zhengqiang Wang, Robert Vince Design and synthesis of dual inhibito...
2008 Zachary K Sweeney, Seth F Harris, Seth F Arora, Hassan Javanbakht, Yingqian Li, Jennifer Fretland, James P Davidson, J Roland Billedeau, Shelley K Gleason, Donald R Hirschfeld, Joshua J Kennedy-Smith, Taraneh Mirzadegan, Ralf Roetz, Mark Smith, Sarah Sperry, Judy M Suh, Jeffrey Wu, Stan Tsing, Armando G Villaseñor, Amber Paul, Guoping Su, Gabrielle M Heilek, Julie Qi Hang, Amy S Zhou, Jesper A Jernelius, Fang-Jie Zhang, Klaus Klumpp Design of annulated pyrazoles as inhi... RT,All properties
2008 Samir Abdurahman, Akos Végvári, Masoud Youssefi, Michael Levi, Stefan Höglund, Elin Andersson, Peter Horal, Bo Svennerholm, Jan Balzarini, Anders Vahlne Activity of the small modified amino ...
2008 Thorsten A Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty, Albert C Liclican, Damian J McColl, Neil H Squires, Eric B Lansdon Triazole derivatives as non-nucleosid... RT,All properties
2008 Chandravanu Dash, Brian J Scarth, Christopher Badorrek, Matthias Götte, Stuart F J Le Grice Examining the ribonuclease H primer g...
2008 Chong Fang, Joseph David Bauman, Kalyan Das, Amanda Remorino, Edward Arnold, Robin M Hochstrasser Two-dimensional infrared spectra reve...
2008 Fang Yu, Xinyong Liu, Peng Zhan, Erik De Clercq Recent advances in the research of HI...
2008 Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Synthesis and biological evaluation o...
2008 Yueping Wang, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque Non-nucleoside HIV-1 reverse-transcri...
2008 Patrick P Lestienne, François Boudsocq, Jacques E Bonnet Initiation of DNA replication by a th...
2008 Guangwei Yang, Jianhong Wang, Yao Cheng, Ginger E Dutschman, Hiromichi Tanaka, Masanori Baba, Yung-Chi Cheng Mechanism of inhibition of human immu...
2008 Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque Non-nucleoside HIV-1 reverse transcri...
2008 Maryam Ehteshami, Brian J Scarth, Egor P Tchesnokov, Chandravanu Dash, Stuart F J Le Grice, Sabine Hallenberger, Dirk Jochmans, Matthias Götte Mutations M184V and Y115F in HIV-1 re...
2008 Bluma G Brenner, Michel Roger, Daniela D Moisi, Maureen Oliveira, Isabelle Hardy, Reuven Turgel, Hugues Charest, Jean-Pierre Routy, Mark A. Wainberg Transmission networks of drug resista...
2008 Maryam Ehteshami, Greg L Beilhartz, Brian J Scarth, Egor P Tchesnokov, Suzanne McCormick, Brian Wynhoven, P Richard Harrigan, Matthias Götte Connection domain mutations N348I and...
2008 Atsuko Hachiya, Eiichi N Kodama, Stefan G Sarafianos, Matthew M Schuckmann, Yasuko Sakagami, Masao Matsuoka, Masafumi Takiguchi, Hiroyuki Gatanaga, Shinichi Oka Amino acid mutation N348I in the conn...
2008 Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Marco Ponassi, Torsten Unge, Martino Bolognesi Crystal structures of HIV-1 reverse t... RT,All properties
2008 Mitsuki Naganuma, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina 1-deoxyrubralactone, a novel specific...
2008 Takuma Kimura, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Novel azaphilones, kasanosins A and B...
2008 Krista A Delviks-Frankenberry, Galina N Nikolenko, Paul L Boyer, Stephen H Hughes, John M Coffin, Abhay Jere, Vinay K Pathak HIV-1 reverse transcriptase connectio...
2008 Peng Zhan, Xinyong Liu, Yuan Cao, Yan Wang, Christophe Pannecouque, Erik De Clercq 1,2,3-Thiadiazole thioacetanilides as...
2008 Atsushi Kawamoto, Eiichi N Kodama, Stefan G Sarafianos, Yasuko Sakagami, Satoru Kohgo, Kenji Kitano, Noriyuki Ashida, Yuko Iwai, Hiroyuki Hayakawa, Hirotomo Nakata, Hiroyuki Mitsuya, Edward Arnold, Masao Matsuoka 2'-deoxy-4'-C-ethynyl-2-halo-adenosin...
2008 Jingshan Ren, Phillip P Chamberlain, Anna Stamp, Steven A Short, Kurt L Weaver, Karen R Romines, Richard J Hazen, Andrew Freeman, Robert G Ferris, C Webster Andrews, Lawrence R Boone, Joseph H Chan, David K Stammers Structural basis for the improved dru... RT,All properties
2008 Yongcheng Song, Julian M W Chan, Zev Tovian, Aaron Secrest, Eva Nagy, Kilannin Krysiak, Kyle Bergan, Michael A. Parniak, Eric Oldfield Bisphosphonate inhibitors of ATP-medi...
2008 Scott J Garforth, Michael A. Parniak, Vinayaka R Prasad Utilization of a deoxynucleoside diph...
2008 Tatiana Ilina, Michael A. Parniak Inhibitors of HIV-1 reverse transcrip...
2008 Kalyan Das, Joseph David Bauman, Arthur D Clark, Yulia Volovik Frenkel, Paul J Lewi, Aaron J Shatkin, Stephen H Hughes, Edward Arnold High-resolution structures of HIV-1 r... RT,All properties
2008 Michel L Ntemgwa, Thomas D'Aquin Toni, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Maureen Oliveira, Mark A. Wainberg Near full-length genomic analysis of ...
2008 Joseph David Bauman, Kalyan Das, William C Ho, Mukta Baweja, Daniel M Himmel, Arthur D Clark, Deena A Oren, Paul L Boyer, Stephen H Hughes, Aaron J Shatkin, Edward Arnold Crystal engineering of HIV-1 reverse ... RT,All properties
2008 Jiaping Lai, Jun Wang, Zongwei Cai Nucleoside reverse transcriptase inhi...
2008 Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte Delayed chain termination protects th...
2008 Lu Gao, Mark Nils Hanson, Mini Balakrishnan, Paul L Boyer, Bernard P Roques, Stephen H Hughes, Baek Kim, Robert A Bambara Apparent defects in processive DNA sy...
2008 Michaela Wendeler, Hsiu-Fang Lee, Alun Bermingham, Jennifer T Miller, Oleg Chertov, Marion K Bona, Noel S Baichoo, Maryam Ehteshami, John A Beutler, Barry R O'Keefe, Matthias Götte, Mamuka Kvaratskhelia, Stuart F J Le Grice Vinylogous ureas as a novel class of ...
2008 Jangsuk Oh, Mary Jane McWilliams, John G Julias, Stephen H Hughes Mutations in the U5 region adjacent t...
2008 Zhengqiang Wang, Robert Vince Synthesis of pyrimidine and quinolone...
2008 Bechan Sharma, Emmanuele Crespan, Giuseppe Villani, Giovanni Maga The balance between the rates of inco...
2008 Maryam Ehteshami, Matthias Götte Effects of mutations in the connectio...
2008 Marco Radi, Chiara Falciani, Lorenzo Contemori, Elena Petricci, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Montserrat Terrazas, Marinunzia Castria, Andrea Togninelli, José A Esté, Imma Clotet-Codina, Mercedes Armand-Ugón, Maurizio Botta A multidisciplinary approach for the ...
2008 Alberta Samuele, Marcella Facchini, Dante Rotili, Antonello Mai, Marino Artico, Mercedes Armand-Ugón, José A Esté, Giovanni Maga Substrate-induced stable enzyme-inhib...
2008 Samantha Zanoli, Sandra Gemma, Stefania Butini, Margherita Brindisi, Bhupendra P Joshi, Giuseppe Campiani, Caterina Fattorusso, Marco Persico, Emmanuele Crespan, Reynel Cancio, Silvio Spadari, Ulrich Hübscher, Giovanni Maga Selective targeting of the HIV-1 reve...
2008 Anna-Maria Monforte, Angela Rao, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Maria Letizia Barreca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri Novel N1-substituted 1,3-dihydro-2H-b...
2008 Zachary K Sweeney, James P Dunn, Yingqian Li, Gabrielle M Heilek, Pete W Dunten, Todd R Elworthy, Xiaochun Han, Seth F Harris, Donald R Hirschfeld, J Heather Hogg, Walter Huber, Ann C Kaiser, Denis J Kertesz, Woongki Kim, Taraneh Mirzadegan, Michael G Roepel, Y David Saito, Tania M P C Silva, Steven Swallow, Jahari L Tracy, Armando Villasenor, Harit Vora, Amy S Zhou, Klaus Klumpp Discovery and optimization of pyridaz... RT,All properties
2008 Roger G Ptak, Philippe A Gallay, Dirk Jochmans, Andrew P Halestrap, Urs T Ruegg, Luke A Pallansch, Michael D Bobardt, Marie-Pierre P De Béthune, Johan Neyts, Erik De Clercq, Jean-Maurice Dumont, Pietro Scalfaro, Kamel Besseghir, Roland M Wenger, Brigitte Rosenwirth Inhibition of human immunodeficiency ...
2008 Matthew D Cullen, York-Fong Cheung, Miles D Houslay, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Investigation of the alkenyldiarylmet...
2008 Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq Design and synthesis of 2-(2,6-dibrom...
2008 Ravindra K Rawal, Rajkamal Tripathi, Smitha Kulkarni, R Paranjape, S B Katti, Christophe Pannecouque, Erik De Clercq 2-(2,6-Dihalo-phenyl)-3-heteroaryl-2-...
2008 Erik De Clercq Emerging antiviral drugs.
2008 Zhijian Zhao, Scott E Wolkenberg, Philip E J Sanderson, Meiqing Lu, Vandna Munshi, Gregory Moyer, Meizhen Feng, Anthony V Carella, Linda T Ecto, Lori J Gabryelski, Ming-Tain Lai, Sridar G Prasad, Youwei Yan, Georgia B McGaughey, Michael D Miller, Craig W Lindsley, George D Hartman, Joseph P Vacca, Theresa M Williams Novel indole-3-sulfonamides as potent... RT,All properties
2007 Jingde Wu, Xinyong Liu, Xianchao Cheng, Yuan Cao, Defeng Wang, Zhongjie Li, Wenfang Xu, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq Synthesis of novel derivatives of 4-a...
2007 Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J Low, Peter K Cheung, P Richard Harrigan, Thomas Lengauer, Francisco S Domingues Structural descriptors of gp120 V3 lo...
2007 Hikaru Yamanaka, Hiroyuki Gatanaga, Pope Kosalaraksa, Saori Matsuoka-Aizawa, Tomonori Takahashi, Seisuke Kimura, Shinichi Oka Novel mutation of human DNA polymeras...
2007 Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, David Moore, Benita Yip, Evan Wood, Julio S G Montaner Continued improvement in survival amo...
2007 Tobias Sing, Andrew J Low, Niko Beerenwinkel, Oliver Sander, Peter K Cheung, Francisco S Domingues, Joachim Büch, Martin Däumer, Rolf Kaiser, Thomas Lengauer, P Richard Harrigan Predicting HIV coreceptor usage on th...
2007 Adrian S Ray, Joy Y Feng, Eisuke Murakami, Chung K Chu, Raymond F Schinazi, Karen S Anderson Interaction of 2'-deoxyguanosine trip...
2007 Jianbin Wang, H X Wang, T B Ng A peptide with HIV-1 reverse transcri...
2007 Wei-Hao Liao, Kuo-Jung Huang, Yu-Fen Chang, Shiu-Mei Wang, Ying-Tzu Tseng, Chien-Cheng Chiang, Jaang-Jiun Wang, Chin-Tien Wang Incorporation of human immunodeficien...
2007 Christian Castro, Eric D Smidansky, Kenneth R Maksimchuk, Jamie J Arnold, Victoria S Korneeva, Matthias Götte, William H Konigsberg, Craig E Cameron Two proton transfers in the transitio...
2007 Jianing Wang, Yunho Jin, Kimberly L Rapp, Raymond F Schinazi, Chung K Chu D- and L-2',3'-didehydro-2',3'-dideox...
2007 Zabrina L Brumme, Chanson J Brumme, Celia K S Chui, Theresa Mo, Brian Wynhoven, Conan K Woods, Bethany M Henrick, Robert S Hogg, Julio S G Montaner, P Richard Harrigan Effects of human leukocyte antigen cl...
2007 Zhengqiang Wang, Eric M Bennett, Daniel J Wilson, Christine E Salomon, Robert Vince Rationally designed dual inhibitors o...
2007 Soo-Huey Yap, Chih-Wei Sheen, Jonathan Fahey, Mark Zanin, David Tyssen, Viviane Dias Lima, Brian Wynhoven, Michael Kuiper, Nicolas Sluis-Cremer, P Richard Harrigan, Gilda Tachedjian N348I in the connection domain of HIV... RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Storage requirements,RNase H,All properties
2007 L W Y Tam, Robert S Hogg, Benita Yip, J S G Montaner, P Richard Harrigan, Chanson J Brumme Performance of a World Health Organiz...
2007 Silvia Bertagnolio, Luis Soto-Ramirez, Richard Pilon, Roberto Rodriguez, Monica Viveros, Luis Fuentes, P Richard Harrigan, Theresa Mo, Don Sutherland, Paul Sandstrom HIV-1 drug resistance surveillance us...
2007 M R Loutfy, J M Raboud, J S G Montaner, T Antoniou, Brian Wynhoven, F Smaill, D Rouleau, J Gill, W Schlech, Zabrina L Brumme, Theresa Mo, K Gough, A Rachlis, P Richard Harrigan, S L Walmsley Assay of HIV gp41 amino acid sequence...
2007 Matthew D Cullen, Bo-Liang Deng, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Synthesis and biological evaluation o...
2007 Giovanni Maga, Marco Radi, Samantha Zanoli, Fabrizio Manetti, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Chiara Falciani, Montserrat Terrazas, Jaume Vilarrasa, Maurizio Botta Discovery of non-nucleoside inhibitor...
2007 Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna-Maria Monforte, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Alba Chimirri Discovery of novel benzimidazolones a...
2007 Reynel Cancio, Antonello Mai, Dante Rotili, Marino Artico, Gianluca Sbardella, Imma Clotet-Codina, José A Esté, Emmanuele Crespan, Samantha Zanoli, Ulrich Hübscher, Silvio Spadari, Giovanni Maga Slow-, tight-binding HIV-1 reverse tr...
2007 Kassim F Adebambo, Samantha Zanoli, Michael G Thomas, Reynel Cancio, Nicola M Howarth, Giovanni Maga N2-benzyloxycarbonylguan-9-yl acetic ...
2007 Stefania Paolucci, Fausto Baldanti, Giulia Campanini, Reynel Cancio, Amalia Belfiore, Giovanni Maga, Giuseppe Gerna NNRTI-selected mutations at codon 190...
2007 Giuseppe La Regina, Antonio Coluccia, Francesco Piscitelli, Alberto Bergamini, Anna Sinistro, Antonella Cavazza, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Ettore Novellino, Marino Artico, Romano Silvestri Indolyl aryl sulfones as HIV-1 non-nu...
2007 Michael G Thomas, Giovanni Maga, Jean-François Mouscadet, Nicola M Howarth Investigation of novel lipid-function...
2007 Guangwei Yang, Ginger E Dutschman, Chuan-Jen Wang, Hiromichi Tanaka, Masanori Baba, Karen S Anderson, Yung-Chi Cheng Highly selective action of triphospha...
2007 Paul L Boyer, John G Julias, Zandrea Ambrose, Maqbool A Siddiqui, Victor E Marquez, Stephen H Hughes The nucleoside analogs 4'C-methyl thy...
2007 Celia K S Chui, Zabrina L Brumme, Chanson J Brumme, Benita Yip, Elizabeth J Phillips, Julio S G Montaner, P Richard Harrigan A simple screening approach to reduce...
2007 Sonia de Castro, Graziela Andrei, Robert Snoeck, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez Novel non-nucleoside human cytomegalo...
2007 Tokumi Maruyama, Yosuke Demizu, Shigetada Kozai, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq Antiviral activity of 3-(3,5-dimethyl...
2007 Bruno Marchand, Kirsten L White, John K Ly, Nicolas A Margot, Ruth Wang, Martin J McDermott, Michael D Miller, Matthias Götte Effects of the translocation status o...
2007 Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh, Eiichi N Kodama, Guangwei Yang, Christopher M Bailey, Satoru Kohgo, Hiroyuki Hayakawa, Masao Matsuoka, Karen S Anderson, Yung-Chi Cheng, Hiroyuki Mitsuya Activity against human immunodeficien...
2007 Matthias Götte Should we include connection domain m...
2007 Naoko Iwata, Hiroaki Yoshida, Minoru Tobiume, Fumiko Ono, Takuya Shimazaki, Tetsutaro Sata, Noriko Nakajima Simian fetal brain progenitor cells f...
2007 J Scott Daniels, Robert Espina, Kevin Cao, Haodan Yuan, Jianrong Lin, Sharon Diamond, Barry Johnson, James Rodgers, Shimoga Prakash, Steve Unger, David Christ, Gerald Miwa, Liang-Shang Gan, Abdul Mutlib Species-specific, P450- and sulfotran...
2007 Lei Ji, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Synthesis and anti-HIV-1 activity eva...
2007 Matthias Götte Mechanisms of resistance associated w...
2007 George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Matthias Gotte, Janice D Pata, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice Investigating the "steric gate" of hu...
2007 Scott J Garforth, Tae Woo Kim, Michael A. Parniak, Eric T Kool, Vinayaka R Prasad Site-directed mutagenesis in the fing...
2007 Lingjie Liao, Hui Xing, Xincang Li, Yuhua Ruan, Yongqing Zhang, Guangming Qin, Yiming Shao Genotypic analysis of the protease an...
2007 Kristel Van Laethem, Christophe Pannecouque, Anne-Mieke Vandamme Mutations at 65 and 70 within the con...
2007 Kalyan Das, Stefan G Sarafianos, Arthur D Clark, Paul L Boyer, Stephen H Hughes, Edward Arnold Crystal structures of clinically rele...
2007 Galina N Nikolenko, Krista A Delviks-Frankenberry, Sarah Palmer, Frank Maldarelli, Matthew J Fivash, John M Coffin, Vinay K Pathak Mutations in the connection domain of...
2007 Marleen C D G Huigen, Loek de Graaf, Dirk Eggink, Rob Schuurman, Viktor Müller, Anna Stamp, David K Stammers, Charles A B Boucher, Monique Nijhuis Evolution of a novel 5-amino-acid ins...
2007 Chanson J Brumme, P Richard Harrigan, Emma C Preston, Winnie W Y Dong, Brian Wynhoven, Carol Murphy, Julio S G Montaner Transmission of drug-resistant HIV-1 ...
2007 Andrew J Low, Winnie W Y Dong, Dennison Chan, Tobias Sing, Ronald Swanstrom, Mark Jensen, Satish Pillai, Benjamin Good, P Richard Harrigan Current V3 genotyping algorithms are ...
2007 Katharina Skrabal, Andrew J Low, Winnie W Y Dong, Tobias Sing, Peter K Cheung, Fabrizio Mammano, P Richard Harrigan Determining human immunodeficiency vi...
2007 Dirk Daelemans, Richard Lu, Erik De Clercq, Alan Engelman Characterization of a replication-com...
2007 Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq Synthesis and evaluation of 2-(2,6-di...
2007 Erik De Clercq Anti-HIV drugs.
2007 Takeshi Sakamoto, Matthew D Cullen, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Synthesis and anti-HIV activity of ne...
2007 Ravindra K Rawal, Raj Kamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq Synthesis and biological evaluation o...
2007 Jan Balzarini, Barbara Orzeszko, Jan K Maurin, Andrzej Orzeszko Synthesis and anti-HIV studies of 2-a...
2007 Clara E Cases-González, Sandra Franco, Miguel Angel Martínez, L Menéndez-Arias Mutational patterns associated with t...
2007 Lei Ji, Fen-Er Chen, Bin Xie, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Synthesis and anti-HIV activity evalu...
2007 Bruno Marchand, Egor P Tchesnokov, Matthias Götte The pyrophosphate analogue foscarnet ... RT,All properties
2007 Marshall L Morningstar, Thomas Roth, David W Farnsworth, Marilyn B Kroeger Smith, Karen M Watson, Robert W Buckheit, Kalyan Das, Weiming Zhang, Edward Arnold, John G Julias, Stephen H Hughes, Christopher J Michejda Synthesis, biological activity, and c...
2007 P Richard Harrigan, Theresa Mo, Jennifer Hirsch, Zabrina L Brumme, Paula McKenna, Lee Bacheler A 21-base pair insertion/duplication ...
2007 Sanjeewa Dharmasena, Zita Pongracz, Edward Arnold, Stefan G Sarafianos, Michael A. Parniak 3'-Azido-3'-deoxythymidine-(5')-tetra... RT,All properties
2007 Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, Joseph H Chan, Jörg-Peter Kleim, David K Stammers Relationship of potency and resilienc... RT,All properties
2007 Elizabeth J Phillips, Sonia Gutiérrez, Natalie Jahnke, Benita Yip, Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, Julio S G Montaner Determinants of nevirapine hypersensi...
2007 Krista A Delviks-Frankenberry, Galina N Nikolenko, Rebekah Barr, Vinay K Pathak Mutations in human immunodeficiency v...
2007 Qianwei Han, Stefan G Sarafianos, Edward Arnold, Michael A. Parniak, Barbara L Gaffney, Roger A Jones Synthesis of AZTpSpCX2ppSA and AZTpSp...
2007 Paul L Boyer, Carolyn R Stenbak, David Hoberman, Maxine L Linial, Stephen H Hughes In vitro fidelity of the prototype pr... Full length or truncated,Frameshift Error Rate,Nucleotide Substitution Rate,Overall Error Rate,All properties
2007 Alok Mulky, B Christie Vu, Joan A Conway, Stephen H Hughes, John C Kappes Analysis of amino acids in the beta7-...
2007 Fernando A Frankel, Cédric F Invernizzi, Maureen Oliveira, Mark A. Wainberg Diminished efficiency of HIV-1 revers...
2007 Fernando A Frankel, Dimitrios Coutsinos, Hongtao Xu, Mark A. Wainberg Kinetics of inhibition of HIV type 1 ...
2007 Yazan El Safadi, Valérie Vivet-Boudou, Roland Marquet HIV-1 reverse transcriptase inhibitors. RT,All properties
2007 Shinji Kamisuki, Chisato Ishimaru, Kadohiro Onoda, Isoko Kuriyama, Noriko Ida, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Nodulisporol and Nodulisporone, novel...
2007 Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia K S Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P Richard Harrigan Evidence of differential HLA class I-...
2007 Dirk Eggink, Marleen C D G Huigen, Charles A B Boucher, Matthias Götte, Monique Nijhuis Insertions in the beta3-beta4 loop of...
2007 William C Drosopoulos, Vinayaka R Prasad The active site residue Valine 867 in...
2006 Hiroshi Ohrui, Satoru Kohgo, Hiroyuki Hayakawa, Eiichi N Kodama, Masao Matsuoka, Tomohiro Nakata, Hiroyuki Mitsuya 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosi... RT,All properties
2006 Dirk Jochmans, Jérôme Deval, Bart Kesteleyn, Herwig Van Marck, Eva Bettens, Inky De Baere, Pascale Dehertogh, Tania Ivens, Marcia Van Ginderen, Bertrand Van Schoubroeck, Maryam Ehteshami, Piet Wigerinck, Matthias Götte, Kurt Hertogs Indolopyridones inhibit human immunod... RT,All properties
2006 Matthias Götte Effects of nucleotides and nucleotide... RT,All properties
2006 Jiong Wang, Carrie Dykes, R A Domaoal, Christine E Koval, R A Bambara, Lisa M Demeter The HIV-1 reverse transcriptase mutan...
2006 Zandrea Ambrose, John G Julias, Paul L Boyer, Vineet N Kewalramani, Stephen H Hughes The level of reverse transcriptase (R...
2006 Frank Goebel, Alexy Yakovlev, Anton L Pozniak, Elena Vinogradova, Griet Boogaerts, Richard Hoetelmans, Marie-Pierre P De Béthune, Monika Peeters, Brian Woodfall Short-term antiviral activity of TMC2...
2006 Antonio Lavecchia, Roberta Costi, Marino Artico, Gaetano Miele, Ettore Novellino, Alberto Bergamini, Emmanuele Crespan, Giovanni Maga, Roberto Di Santo Arylthiopyrrole (AThP) derivatives as...
2006 Roberto Di Santo, Roberta Costi, Marino Artico, Gaetano Miele, Antonio Lavecchia, Ettore Novellino, Alberto Bergamini, Reynel Cancio, Giovanni Maga Arylthiopyrrole (AThP) derivatives as...
2006 Daniel M Himmel, Stefan G Sarafianos, Sanjeewa Dharmasena, Mohammed M Hossain, Kessler McCoy-Simandle, Tatiana Ilina, Arthur D Clark, Jennifer L Knight, John G Julias, Patrick K Clark, Karsten Krogh-Jespersen, Ronald M Levy, Stephen H Hughes, Michael A. Parniak, Edward Arnold HIV-1 reverse transcriptase structure... RT,RNase H,All properties
2006 Gabriella De Martino, Giuseppe La Regina, Rino Ragno, Antonio Coluccia, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri Indolyl aryl sulphones as HIV-1 non-n...
2006 Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong Novel nonnucleoside inhibitors that s...
2006 Jingshan Ren, Charles E Nichols, Anna Stamp, Phillip P Chamberlain, Robert G Ferris, Kurt L Weaver, Steven A Short, David K Stammers Structural insights into mechanisms o...
2006 Roberto Di Santo, Roberta Costi, Marino Artico, Rino Ragno, Antonio Lavecchia, Ettore Novellino, Enrico Gavuzzo, Francesco La Torre, Roberto Cirilli, Reynel Cancio, Giovanni Maga Design, synthesis, biological evaluat...
2006 Carlos Cruchaga, Elena Ansó, Ana Rouzaut, Juan J Martínez-Irujo Selective excision of chain-terminati...
2006 Paul L Boyer, Stefan G Sarafianos, Patrick K Clark, Edward Arnold, Stephen H Hughes Why do HIV-1 and HIV-2 use different ...
2006 Monica E Hamburgh, Kenneth A Curr, Melissa Monaghan, Vasudev R Rao, Snehlata Tripathi, Bradley D Preston, Stefan G Sarafianos, Edward Arnold, Thomas Darden, Vinayaka R Prasad Structural determinants of slippage-m...
2006 María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, Federico Gago Dimerization inhibitors of HIV-1 reve...
2006 Tokumi Maruyama, Shigetada Kozai, Yosuke Demizu, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq Synthesis and anti-HIV-1 and anti-HCM...
2006 Sarit Aviel-Ronen, Chang Qi Zhu, Bradley P Coe, Ni Liu, Spencer K Watson, Wan L Lam, Ming Sound Tsao Large fragment Bst DNA polymerase for...
2006 María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, María-Cruz Bonache, Sonia de Castro TSAO derivatives, inhibitors of HIV-1...
2006 N Machouf, R Thomas, V K Nguyen, B Trottier, M R Boulassel, Mark A. Wainberg, Jean-Pierre Routy Effects of drug resistance on viral l...
2006 Lei Ji, Fen-Er Chen, Xiao-Qing Feng, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Non-nucleoside HIV-1 reverse transcri...
2006 Nicolas Sluis-Cremer, Noureddine Hamamouch, Ana San Félix, Sonsoles Velazquez, Jan Balzarini, María-José Camarasa Structure-activity relationships of [...
2006 Kirsten L White, James M Chen, Joy Y Feng, Nicolas A Margot, John K Ly, Adrian S Ray, Holly L Macarthur, Martin J McDermott, S Swaminathan, Michael D Miller The K65R reverse transcriptase mutati...
2006 Christine E Koval, Carrie Dykes, Jiong Wang, Lisa M Demeter Relative replication fitness of efavi...
2006 Enzo Tramontano HIV-1 RNase H: recent progress in an ...
2006 Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes Combining mutations in HIV-1 reverse ...
2006 Carrie Dykes, Jiong Wang, Xia Jin, Vicente Planelles, Dong Sung An, Amanda Tallo, Yangxin Huang, Hulin Wu, Lisa M Demeter Evaluation of a multiple-cycle, recom...
2006 Klaus Klumpp, Tara Mirzadegan Recent progress in the design of smal...
2006 Najim A Al-Masoudi, Yaseen A Al-Soud, Aris Kalogerakis, Christophe Pannecouque, Erik De Clercq Nitroimidazoles, part 2: Synthesis, a...
2006 CF Perno, Valentina Svicher, Dominique Schols, Michela Pollicita, Jan Balzarini, Stefano Aquaro Therapeutic strategies towards HIV-1 ...
2006 Bo-Liang Deng, Matthew D Cullen, Zhigang Zhou, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman Synthesis and anti-HIV activity of ne...
2006 Varuni K Jamburuthugoda, Pauline Chugh, Baek Kim Modification of human immunodeficienc...
2006 Valentina Svicher, Tobias Sing, Maria Mercedes Santoro, Federica Forbici, Fátima Rodríguez-Barrios, Ada Bertoli, Niko Beerenwinkel, Maria Concetta Bellocchi, Federigo Gago, Antonella d'Arminio Monforte, Andrea Antinori, Thomas Lengauer, F Ceccherini-Silberstein, CF Perno Involvement of novel human immunodefi...
2005 Scott R Budihas, Inna Gorshkova, Sergei A Gaidamakov, Antony Wamiru, Marion K Bona, Michael A. Parniak, Robert J Crouch, James B McMahon, John A Beutler, Stuart F J Le Grice Selective inhibition of HIV-1 reverse...
2005 Paul A J Janssen, Paul J Lewi, Edward Arnold, Frits F D Daeyaert, Marc R De Jonge, Jan Heeres, Luc Koymans, Maarten H Vinkers, Jérôme Guillemont, Elisabeth Pasquier, Michael Kukla, Don Ludovici, Koen Andries, Marie-Pierre P De Béthune, Rudi Pauwels, Kalyan Das, Arthur D Clark, Yulia Volovik Frenkel, Stephen H Hughes, Bart Medaer, Fons De Knaep, Hilde Bohets, Fred De Clerck, Ann Lampo, Peter Williams, Paul Stoffels In search of a novel anti-HIV drug: m...
2005 Alok Mulky, Stefan G Sarafianos, Yujiang Jia, Edward Arnold, John C Kappes Identification of amino acid residues...
2005 Joël Didierjean, Catherine Isel, Flore Querré, Jean-François Mouscadet, Anne-Marie Aubertin, Jean-Yves Valnot, Serge R Piettre, Roland Marquet Inhibition of human immunodeficiency ...
2005 Fernando A Frankel, Bruno Marchand, Dan Turner, Matthias Götte, Mark A. Wainberg Impaired rescue of chain-terminated D...
2005 Daniel M Himmel, Kalyan Das, Arthur D Clark, Stephen H Hughes, Abdellah Benjahad, Said Oumouch, Jérôme Guillemont, Sophie Coupa, Alain Poncelet, Imre Csoka, Christophe Meyer, Koen Andries, Chi Hung Nguyen, David S Grierson, Edward Arnold Crystal structures for HIV-1 reverse ... RT,Associated condition,All properties
2005 Erik De Clercq Emerging anti-HIV drugs.
2005 Myriam Witvrouw, Valery Fikkert, Anke Hantson, Christophe Pannecouque, Barry R O'keefe, James McMahon, Leonidas Stamatatos, Erik De Clercq, Anders Bolmstedt Resistance of human immunodeficiency ...
2005 Bo-Liang Deng, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman Synthesis, anti-HIV activity, and met...
2005 Michael E Ignatov, Anthony J Berdis, Stuart F J Le Grice, Mary D Barkley Attenuation of DNA replication by HIV...
2005 Rienk E Jeeninga, Barbara Jan, Birgit van der Linden, Henk van den Berg, Ben Berkhout Construction of a minimal HIV-1 varia...
2005 Ronald B Geskus, Laurence Meyer, Jean-Baptiste Hubert, Hanneke Schuitemaker, Ben Berkhout, Christine Rouzioux, Ioannis D Theodorou, Jean-François Delfraissy, Maria Prins, Roel A Coutinho Causal pathways of the effects of age...
2005 Ben Berkhout, Anthony de Ronde, Lia van der Hoek Aggressive HIV-1?
2005 Luis R Miranda, Matthias Götte, Fei Liang, Daniel R Kuritzkes The L74V mutation in human immunodefi...
2005 Nicolas Sluis-Cremer, Dominique Arion, Urvi Parikh, Dianna Koontz, Raymond F Schinazi, John W Mellors, Michael A. Parniak The 3'-azido group is not the primary...
2005 Lia van der Hoek, Nicole Back, Maarten F Jebbink, Anthony de Ronde, Margreet Bakker, Suzanne Jurriaans, Peter Reiss, Neil Parkin, Ben Berkhout Increased multinucleoside drug resist...
2005 Kirsten L White, Nicolas A Margot, John K Ly, James M Chen, Adrian S Ray, Martina Pavelko, Ruth Wang, Martin J McDermott, S Swaminathan, Michael D Miller A combination of decreased NRTI incor...
2005 Darwin J Operario, Holly M Reynolds, Baek Kim Comparison of DNA polymerase activiti... Molecular Weight,Overall Error Rate,All properties
2005 Jan Balzarini, Miguel Stevens, Erik De Clercq, Dominique Schols, Christophe Pannecouque Pyridine N-oxide derivatives: unusual...
2005 Jan Balzarini, Kristel Van Laethem, Sigrid Hatse, Matheus Froeyen, Els Van Damme, Anders Bolmstedt, Willy Peumans, Erik De Clercq, Dominique Schols Marked depletion of glycosylation sit...
2005 Jan Balzarini, Joeri Auwerx, Fátima Rodríguez-Barrios, Allel Chedad, Viktor Farkas, F Ceccherini-Silberstein, Carlos García-Aparicio, Sonsoles Velázquez, Erik De Clercq, CF Perno, María-José Camarasa, Federico Gago The amino acid Asn136 in HIV-1 revers...
2005 Joeri Auwerx, Joke Van Nieuwenhove, Fátima Rodríguez-Barrios, Sonia de Castro, Sonsoles Velázquez, F Ceccherini-Silberstein, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini The N137 and P140 amino acids in the ...
2005 Fátima Rodríguez-Barrios, Jan Balzarini, Federico Gago The molecular basis of resilience to ...
2005 Joeri Auwerx, Fátima Rodríguez-Barrios, F Ceccherini-Silberstein, Ana San-Félix, Sonsoles Velázquez, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini The role of Thr139 in the human immun...
2005 Albert Nguyen Van Nhien, Cyrille Tomassi, Christophe Len, José Luis Marco-Contelles, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Denis Postel First synthesis and evaluation of the...
2005 F Ceccherini-Silberstein, Federico Gago, Maria Mercedes Santoro, Caterina Gori, Valentina Svicher, Fátima Rodríguez-Barrios, Roberta d'Arrigo, Massimo Ciccozzi, Ada Bertoli, Antonella d'Arminio Monforte, Jan Balzarini, Andrea Antinori, CF Perno High sequence conservation of human i...
2005 Guang-Fu Sun, Xu-Xiang Chen, Fen-Er Chen, Yue-Ping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Nonnucleoside HIV-1 reverse-transcrip...
2005 Guang-Fu Sun, Yun-Yan Kuang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Non-nucleoside HIV reverse transcript...
2005 Johan Vingerhoets, Hilde Azijn, Els Fransen, Inky De Baere, Liesbet Smeulders, Dirk Jochmans, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune TMC125 displays a high genetic barrie...
2005 Natalia A Lebedeva, T A Seredina, V N Silnikov, T V Abramova, A S Levina, Svetlana N Khodyreva, Nadejda I Rechkunova, Olga I Lavrik Analysis of interactions of DNA polym...
2005 Hong Zang, Thomas M Harris, F Peter Guengerich Kinetics of nucleotide incorporation ...
2005 Hong Zang, Thomas M Harris, F Peter Guengerich Kinetics of nucleotide incorporation ...
2005 Tongfei Wu, Matheus Froeyen, Veerle Kempeneers, Christophe Pannecouque, Jing Wang, Roger Busson, Erik De Clercq, Piet Herdewijn Deoxythreosyl phosphonate nucleosides...
2005 Cathryn A Shaw-Reid, Bradley Feuston, Vandna Munshi, Krista Getty, Julie Krueger, Daria J Hazuda, Michael A. Parniak, Michael D Miller, Dale Lewis Dissecting the effects of DNA polymer...
2005 Michael E Abram, Michael A. Parniak Virion instability of human immunodef...
2005 Daniel Summerer, Andreas Marx 4'C-ethynyl-thymidine acts as a chain...
2005 Micha Nethe, Ben Berkhout, Antoinette C van der Kuyl Retroviral superinfection resistance.
2005 Caterina Fattorusso, Sandra Gemma, Stefania Butini, Paul Huleatt, Bruno Catalanotti, Marco Persico, Meri De Angelis, Isabella Fiorini, Vito Nacci, Anna Ramunno, Manuela Rodriquez, Giovanni Greco, Ettore Novellino, Alberto Bergamini, Stefano Marini, Massimo Coletta, Giovanni Maga, Silvio Spadari, Giuseppe Campiani Specific targeting highly conserved r...
2005 Emmanuele Crespan, Samantha Zanoli, Anastasiya Khandazhinskaya, Igor V Shevelev, Maxim Jasko, Ludmila Alexandrova, Marina Kukhanova, Giuseppina Blanca, Giuseppe Villani, Ulrich Hübscher, Silvio Spadari, Giovanni Maga Incorporation of non-nucleoside triph...
2005 Gabriella De Martino, Giuseppe La Regina, Alessandra Di Pasquali, Rino Ragno, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri Novel 1-[2-(diarylmethoxy)ethyl]-2-me...
2005 Antonello Mai, Marino Artico, Rino Ragno, Gianluca Sbardella, Silvio Massa, Chiara Musiu, Massimo Mura, Flavia Marturana, Alessandra Cadeddu, Giovanni Maga, Paolo La Colla 5-Alkyl-2-alkylamino-6-(2,6-difluorop...
2005 Emmanuele Crespan, Giada A Locatelli, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Giovanni Maga Drug resistance mutations in the nucl...
2005 Hong Li, Zhengqiang Wang, Wei-guo Cui, Yan Liang, Tian-yi Xin, Jinming Li [Study on adherence and interrelated ...
2005 Yaofeng Zhao, Yang Jin, Jing-Houng Wang, Rui-Rui Wang, Liu-Meng Yang, Wen-Hui Lee, Yong-Tang Zheng, Yongqing Zhang A novel heme-containing protein with ...
2005 Junmei Wang, Xinshan Kang, Irwin D Kuntz, Peter A Kollman Hierarchical database screenings for ...
2005 Abdellah Benjahad, Martine Croisy, Claude Monneret, Emile Bisagni, Dominique Mabire, Sophie Coupa, Alain Poncelet, Imre Csoka, Jérôme Guillemont, Christophe Meyer, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Daniel M Himmel, Kalyan Das, Edward Arnold, Chi Hung Nguyen, David S Grierson 4-Benzyl and 4-benzoyl-3-dimethylamin...
2005 Jan Heeres, Marc R De Jonge, Lucien M H Koymans, Frits F D Daeyaert, Maarten H Vinkers, Koen J A Van Aken, Edward Arnold, Kalyan Das, Amuri Kilonda, Georges J Hoornaert, Frans Compernolle, Marek Cegla, Rasha A Azzam, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Paul A J Janssen Design, synthesis, and SAR of a novel...
2005 Kalyan Das, Paul J Lewi, Stephen H Hughes, Edward Arnold Crystallography and the design of ant...
2005 Dan Turner, Bluma G Brenner, Daniela D Moisi, Chen Liang, Mark A. Wainberg Substitutions in the Reverse Transcri...
2005 Ariel Roldan, Otis U Warren, Rodney S Russell, Chen Liang, Mark A. Wainberg A HIV-1 minimal gag protein is superi...
2005 Mark A. Wainberg, James P C Sawyer, Julio S G Montaner, Robert L Murphy, Daniel R Kuritzkes, Francois Raffi Challenges for the clinical developme...
2005 Andrew R Zolopa, Laura C Lazzeroni, Alex Rinehart, Françoise Brun Vezinet, François Clavel, Ann Collier, Brian Conway, Roy M Gulick, Mark Holodniy, CF Perno, Robert W Shafer, Douglas D Richman, Mark A. Wainberg, Daniel R Kuritzkes Accuracy, precision, and consistency ...
2005 Dan Turner, Bluma G Brenner, Daniela Mosis, Chen Liang, Mark A. Wainberg Substitutions in the reverse transcri...
2005 Ariel Fernández, Dan S Tawfik, Ben Berkhout, Rogier W Sanders, Andrzej Kloczkowski, Taner Sen, Bob Jernigan Protein promiscuity: drug resistance ...
2005 Melaku Adal, Workenesh Ayele, Dawit Wolday, Kifle Dagne, Tsehaynesh Messele, Tesfaye Tilahun, Ben Berkhout, Shlomo Mayaan, Georgios Pollakis, Wendelien Dorigo-Zetsma Evidence of genetic variability of hu...
2005 María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez TSAO derivatives the first non-peptid...
2005 Pia S Kivelä, Anneke Krol, Mika O Salminen, Ronald B Geskus, Jukka I Suni, Veli-Jukka Anttila, Kirsi Liitsola, Veera Zetterberg, Frank Miedema, Ben Berkhout, Roel A Coutinho, Matti A Ristola High plasma HIV load in the CRF01-AE ...
2004 Rachelle J Bienstock, Willliam C Copeland Molecular insights into NRTI inhibiti...
2004 Kirsten L White, James M Chen, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Lisa K Naeger, S Swaminathan, Michael D Miller Molecular mechanisms of tenofovir res...
2004 Elena N Peletskaya, Alex A Kogon, Steven Tuske, Edward Arnold, Stephen H Hughes Nonnucleoside inhibitor binding affec... RT,Associated condition,All properties
2004 Maqbool A Siddiqui, Stephen H Hughes, Paul L Boyer, Hiroyuki Mitsuya, Que N Van, Clifford George, Stefan G Sarafinanos, Victor E Marquez A 4'-C-ethynyl-2',3'-dideoxynucleosid...
2004 Myriam Witvrouw, Bénédicte Van Maele, J Vercammen, Anke Hantson, Y Engelborghs, Erik De Clercq, Christophe Pannecouque, Zeger Debyser Novel inhibitors of HIV-1 integration.
2004 Erik De Clercq Non-nucleoside reverse transcriptase ...
2004 Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Marco Petrella, Mark A. Wainberg Rationale for maintenance of the M184...
2004 Peter R Meyer, Anthony J Smith, Suzanne E Matsuura, Walter A Scott Effects of primer-template sequence o...
2004 George R Painter, Merrick R Almond, Shuli Mao, Dennis C Liotta Biochemical and mechanistic basis for... RT,Associated condition,All properties
2004 Lisa F Rezende, Vinayaka R Prasad Nucleoside-analog resistance mutation... RT,Associated condition,All properties
2004 John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes Effects of mutations in the G tract o...
2004 Koen Andries, Hilde Azijn, Theo Thielemans, Donald W Ludovici, Michael Kukla, Jan Heeres, Paul A J Janssen, Bart De Corte, Johan Vingerhoets, Rudi Pauwels, Marie-Pierre P De Béthune TMC125, a novel next-generation nonnu... RT,Associated condition,All properties
2004 Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna-Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà 2-(2,6-Dihalophenyl)-3-(pyrimidin-2-y...
2004 Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, David K Stammers Crystal structures of HIV-1 reverse t...
2004 Julie Qi Hang, Surendran Rajendran, Yanli Yang, Yingqian Li, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin, Klaus Klumpp Activity of the isolated HIV RNase H ...
2004 Yanping He, Fener Chen, Xiongjie Yu, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Nonnucleoside HIV-1 reverse transcrip...
2004 Jeong-Yun Choi, F Peter Guengerich Analysis of the effect of bulk at N2-...
2004 Satoru Kohgo, Kohei Yamada, Kenji Kitano, Yuko Iwai, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui Design, efficient synthesis, and anti...
2004 Bruno Marchand, Matthias Götte Impact of the translocational equilib...
2004 Eisuke Murakami, Adrian S Ray, Raymond F Schinazi, Karen S Anderson Investigating the effects of stereoch...
2004 Michael B Doughty, Karam Aboudehen, Garland Anderson, Ke Li, Bob Moore, Tina Poolson Side-chain conformational restriction...
2004 Paul J Lewi, Edward Arnold, Koen Andries, Hilde Bohets, Herman Borghys, Arthur D Clark, Frits F D Daeyaert, Kalyan Das, Marie-Pierre P De Béthune, Marc R De Jonge, Jan Heeres, Luc Koymans, Jos Leempoels, Jef Peeters, Philip Timmerman, Walter Van den Broeck, Frédéric Vanhoutte, Gerben Van't Klooster, Maarten H Vinkers, Yulia Volovik, Paul A J Janssen Correlations between factors determin...
2004 Giada A Locatelli, Reynel Cancio, Silvio Spadari, Giovanni Maga HIV-1 reverse transcriptase inhibitor...
2004 Stefania Paolucci, Fausto Baldanti, Giovanni Maga, Reynel Cancio, Maurizio Zazzi, Maurizio Zavattoni, Antonella Chiesa, Silvio Spadari, Giuseppe Gerna Gln145Met/Leu changes in human immuno...
2004 Paul L Boyer, Tomozumi Imamichi, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes Effects of the Delta67 complex of mut...
2004 Joy Y Feng, Eisuke Murakami, Suzana M Zorca, Allison A Johnson, Kenneth A Johnson, Raymond F Schinazi, Phillip A Furman, Karen S Anderson Relationship between antiviral activi...
2004 Matthias Götte Inhibition of HIV-1 reverse transcrip...
2004 King C Chan, Scott R Budihas, Stuart F J Le Grice, Michael A. Parniak, Robert J Crouch, Sergei A Gaidamakov, Haleem J Isaaq, Antony Wamiru, James B McMahon, John A Beutler A capillary electrophoretic assay for...
2004 Elisabetta Bulgheroni, Francesco Croce, Paola Citterio, Ottavia Viganò, Raffaella Visonà, Eugenio Sala, Massimo Galli, Stefano Rusconi Unusual codon 69 insertions: influenc...
2004 Dan Turner, Bluma G Brenner, Mark A. Wainberg Relationships among various nucleosid...
2004 Dan Turner, Bluma G Brenner, Daniela D Moisi, Mervi Detorio, Raymond Cesaire, Takashi Kurimura, Haruyo Mori, Max Essex, Shlomo Maayan, Mark A. Wainberg Nucleotide and amino acid polymorphis...
2004 Jérôme Deval, Jean-Marc Navarro, Boulbaba Selmi, Jérôme Courcambeck, Joëlle Boretto, Philippe Halfon, Sarah Garrido-Urbani, Josephine Sire, Bruno Canard A loss of viral replicative capacity ...
2004 Jérôme Deval, Kirsten L White, Michael D Miller, Neil T Parkin, Jérôme Courcambeck, Philippe Halfon, Boulbaba Selmi, Joëlle Boretto, Bruno Canard Mechanistic basis for reduced viral a...
2004 Debanu Das, Millie M Georgiadis The crystal structure of the monomeri...
2004 Zandrea Ambrose, Valerie Boltz, Sarah Palmer, John M Coffin, Stephen H Hughes, Vineet N Kewalramani In vitro characterization of a simian...
2004 John G Julias, Paul L Boyer, Mary Jane McWilliams, W Gregory Alvord, Stephen H Hughes Mutations at position 184 of human im...
2004 A Michael Sismour, Stefan Lutz, Jeong-Ho Park, Michael J Lutz, Paul L Boyer, Stephen H Hughes, Steven A Benner PCR amplification of DNA containing n...
2004 Alok Mulky, Stefan G Sarafianos, Edward Arnold, Xiaoming Wu, John C Kappes Subunit-specific analysis of the huma...
2004 Stefan G Sarafianos, Kalyan Das, Stephen H Hughes, Edward Arnold Taking aim at a moving target: design...
2004 George A Freeman, C Webster Andrews Iii, Andrew L Hopkins, Gina S Lowell, Lee T Schaller, Jill R Cowan, Stephen S Gonzales, George W Koszalka, Richard J Hazen, Lawrence R Boone, Rob G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, David J Reynolds, John Milton, Jingshan Ren, David I Stuart, David K Stammers, Joseph H Chan Design of non-nucleoside inhibitors o... RT,Associated condition,All properties
2004 Joeri Auwerx, Robert Esnouf, Erik De Clercq, Jan Balzarini Susceptibility of feline immunodefici...
2004 Stefan G Sarafianos, Stephen H Hughes, Edward Arnold Designing anti-AIDS drugs targeting t...
2004 Giada A Locatelli, Giuseppe Campiani, Reynel Cancio, Elena Morelli, Anna Ramunno, Sandra Gemma, Ulrich Hübscher, Silvio Spadari, Giovanni Maga Effects of drug resistance mutations ...
2004 Reynel Cancio, Silvio Spadari, Giovanni Maga Vif is an auxiliary factor of the HIV...
2004 Louise Z Wang, George L Kenyon, Kenneth A Johnson Novel mechanism of inhibition of HIV-...
2004 Andrew L Hopkins, Jingshan Ren, John Milton, Richard J Hazen, Joseph H Chan, David I Stuart, David K Stammers Design of non-nucleoside inhibitors o... RT,Associated condition,All properties
2004 Erik De Clercq Antiviral drugs in current clinical use.
2004 Joeri Auwerx, Miguel Stevens, An R Van Rompay, Louise E Bird, Jingshan Ren, Erik De Clercq, Bo Oberg, David K Stammers, Anna Karlsson, Jan Balzarini The phenylmethylthiazolylthiourea non...
2004 Kenji Kitano, Satoru Kohgo, Kohei Yamada, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui Attempt to reduce cytotoxicity by syn...
2004 Claudia M D'Abramo, Luciano Cellai, Matthias Götte Excision of incorporated nucleotide a...
2004 Esther W Hou, Rajendra Prasad, William A Beard, Samuel H Wilson High-level expression and purificatio...
2004 George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Kalavathy Sitaraman, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice Site- and subunit-specific incorporat...
2004 Florence Doualla-Bell, Simane Gaseitsiwe, Thumbi Ndungú, Musetsanagepe Modukanele, Trevor Peter, Vladimir Novitsky, Ndwapi Ndwapi, Gaolathe Tendani, Ava Avalos, William Wester, Hermann Bussmann, Peter Cardiello, Richard G Marlink, Howard Moffat, Ibou Thior, Mark A. Wainberg, Max Essex Mutations and polymorphisms associate...
2004 Mark A. Wainberg The impact of the M184V substitution ...
2004 Steve Tuske, Stefan G Sarafianos, Arthur D Clark, Jianping Ding, Lisa K Naeger, Kirsten L White, Michael D Miller, Craig S Gibbs, Paul L Boyer, Patrick K Clark, Gang Wang, Barbara L Gaffney, Roger A Jones, Donald M Jerina, Stephen H Hughes, Edward Arnold Structures of HIV-1 RT-DNA complexes ...
2004 Nicolas Sluis-Cremer, Dominique Arion, Michael E Abram, Michael A. Parniak Proteolytic processing of an HIV-1 po...
2004 Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà Synthesis of new 2,3-diaryl-1,3-thiaz...
2004 Dan Turner, Ariel Roldan, Bluma G Brenner, Daniela D Moisi, Jean-Pierre Routy, Mark A. Wainberg Variability in the PR and RT genes of...
2004 Jan Balzarini Current status of the non-nucleoside ...
2004 María-José Camarasa, Ana San-Félix, Sonsoles Velázquez, María-Jesús Pérez-Pérez, Federico Gago, Jan Balzarini TSAO compounds: the comprehensive sto...
2004 Maximilian A Silvestri, Muthukaman Nagarajan, Erik De Clercq, Christophe Pannecouque, Mark Cushman Design, synthesis, anti-HIV activitie...
2004 Kalyan Das, Arthur D Clark, Paul J Lewi, Jan Heeres, Marc R De Jonge, Lucien M H Koymans, H Maarten Vinkers, Frederik Daeyaert, Donald W Ludovici, Michael J Kukla, Bart De Corte, Robert W Kavash, Chih Y Ho, Hong Ye, Mark A Lichtenstein, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Paul L Boyer, Patrick K Clark, Stephen H Hughes, Paul A J Janssen, Edward Arnold Roles of conformational and positiona...
2004 CF Perno, Emanuela Balestra, M Francesconi, D Abdelahad, Raffaele Caliò, Jan Balzarini, Stefano Aquaro Antiviral profile of HIV inhibitors i...
2004 Yanping He, Fener Chen, Guangfu Sun, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque 5-Alkyl-2-[(aryl and alkyloxylcarbony...
2004 Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Zeev Rosberger, Michel Roger, Mark A. Wainberg Diminished representation of HIV-1 va...
2003 Peter R Meyer, Johan Lennerstrand, Suzanne E Matsuura, Brendan A Larder, Walter A Scott Effects of dipeptide insertions betwe...
2003 Maria Letizia Barreca, Alba Chimirri, Erik De Clercq, Laura De Luca, Anna-Maria Monforte, Pietro Monforte, Angela Rao, Maria Zappalà Anti-HIV agents: design and discovery...
2003 Marilyn B Kroeger Smith, Brian M Hose, Arie Hawkins, James Lipchock, David W Farnsworth, Robert C Rizzo, Julian Tirado-Rives, Edward Arnold, Weiming Zhang, Stephen H Hughes, William L Jorgensen, Christopher J Michejda, Richard H Smith Molecular modeling calculations of HI...
2003 Nicolas Sluis-Cremer, Ellis Kempner, Michael A. Parniak Structure-activity relationships in H...
2003 Michael A. Parniak, Kyung-Lyum Min, Scott R Budihas, Stuart F J Le Grice, John A Beutler A fluorescence-based high-throughput ...
2003 Romas Geleziunas, Karen Gallagher, Hangchun Zhang, Lee Bacheler, Sena Garber, Jing-Tao Wu, Guoen Shi, Michael J Otto, Raymond F Schinazi, Susan Erickson-Viitanen HIV-1 resistance profile of the novel...
2003 Joel E Gallant, Peter Z Gerondelis, Mark A. Wainberg, Nancy S Shulman, Richard H Haubrich, Marty St Clair, Ernest R Lanier, Nicholas S Hellmann, Douglas D Richman Nucleoside and nucleotide analogue re... RT,Associated condition,All properties
2003 Tokumi Maruyama, Shigetada Kozai, Tetsuo Yamasaki, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoeck, Graciella Andrei, Erik De Clercq Synthesis and antiviral activity of 1...
2003 Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, Jingshan Ren, David I Stuart, David K Stammers Cloning, expression, purification, an...
2003 Myriam Witvrouw, Christophe Pannecouque, Valery Fikkert, Anke Hantson, Barbara Van Remoortel, Marjan Hezareh, Erik De Clercq, Stephen J Brown Potent and selective inhibition of HI...
2003 Karidia Diallo, Bluma G Brenner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Matthias Götte, Mark A. Wainberg The M184V substitution in human immun...
2003 Wei Huang, Andrea Gamarnik, Kay Limoli, Christos J Petropoulos, Jeannette M Whitcomb Amino acid substitutions at position ...
2003 Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg Negative effect of the M184V mutation...
2003 William A Beard, Samuel H Wilson Structural insights into the origins ...
2003 Adrian S Ray, Eisuke Murakami, Aravind Basavapathruni, Joseph A Vaccaro, Dagny Ulrich, Chung K Chu, Raymond F Schinazi, Karen S Anderson Probing the molecular mechanisms of A...
2003 Jaroslaw Poznanski, Maria Bretner, Tadeusz Kulikowski, Jan Balzarini, Arthur Van Aerschot, Erik De Clercq Synthesis, solution conformation and ...
2003 Adrian S Ray, Raymond F Schinazi, Eisuke Murakami, Aravind Basavapathruni, Junxing Shi, Suzana M Zorca, Chung K Chu, Karen S Anderson Probing the mechanistic consequences ... RT,Associated condition,All properties
2003 Susan E Lim, Mikhail V Ponamarev, Matthew J Longley, William C Copeland Structural determinants in human DNA ...
2003 Yudong Quan, Bluma G Brenner, Maureen Oliveira, Mark A. Wainberg Lamivudine can exert a modest antivir...
2003 Bluma G Brenner, Dan Turner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Mauricio Carobene, Richard G Marlink, Jonathan Schapiro, Michel Roger, Mark A. Wainberg A V106M mutation in HIV-1 clade C vir...
2003 Ge Meng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Nonnucleoside HIV-1 reverse transcrip...
2003 Karidia Diallo, Bruno Marchand, Xin Wei, Luciano Cellai, Matthias Götte, Mark A. Wainberg Diminished RNA primer usage associate...
2003 Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini Inhibition of human immunodeficiency ...
2003 Peter R Meyer, Suzanne E Matsuura, Dianna Zonarich, Rahul R Chopra, Eric Pendarvis, Holly Z Bazmi, John W Mellors, Walter A Scott Relationship between 3'-azido-3'-deox...
2003 Eisuke Murakami, Joy Y Feng, Harold R Lee, Jeremiah Hanes, Kenneth A Johnson, Karen S Anderson Characterization of novel reverse tra...
2003 María-Cruz Bonache, Cristina Chamorro, Esther Lobatón, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, Ana San-Félix Structure-activity relationship studi...
2003 Bruno Marchand, Matthias Götte Site-specific footprinting reveals di...
2003 Cathryn A Shaw-Reid, Vandna Munshi, Pia Graham, Abigail Wolfe, Marc Witmer, Renee Danzeisen, David B Olsen, Steven S Carroll, Mark Embrey, John S Wai, Michael D Miller, James L Cole, Daria J Hazuda Inhibition of HIV-1 ribonuclease H by...
2003 Boulbaba Selmi, Jerome Deval, Karine Alvarez, Joelle Boretto, Simon Sarfati, Catherine Guerreiro, Bruno Canard The Y181C substitution in 3'-azido-3'...
2003 Marie L Coté, Mark Pflomm, Millie M Georgiadis Staying straight with A-tracts: a DNA...
2003 Giuseppina Blanca, Fausto Baldanti, Stefania Paolucci, Alexander Yu Skoblov, Lyubov Victorova, Ulrich Hübscher, Giuseppe Gerna, Silvio Spadari, Giovanni Maga Nevirapine resistance mutation at cod...
2003 Qian Zhao, Hong Lu, Dominique Schols, Erik De Clercq, Shibo Jiang Development of a cell-based enzyme-li...
2003 Mélanie Girouard, Karidia Diallo, Bruno Marchand, Suzanne McCormick, Matthias Götte Mutations E44D and V118I in the rever...
2003 Evguenia S Svarovskaia, Sara R Cheslock, Wen-Hui Zhang, Wei-Shau Hu, Vinay K Pathak Retroviral mutation rates and reverse...
2003 John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes Mutation of amino acids in the connec...
2003 Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes Mutations in the 5' end of the human ...
2003 Sanjay U C Sankatsing, Gerrit J Weverling, Monika Peeters, Gerben van't Klooster, Boris Gruzdev, Aza Rakhmanova, Sven A Danner, Suzanne Jurriaans, Jan M Prins, Joep M A Lange TMC125 exerts similar initial antivir...
2003 Martin Stürmer, Schlomo Staszewski, Hans-Wilhelm Doerr, Brendan A Larder, Stuart Bloor, Kurt Hertogs Correlation of phenotypic zidovudine ...
2003 Harold R Lee, Jeremiah Hanes, Kenneth A Johnson Toxicity of nucleoside analogues used...
2003 Giuseppina Blanca, Igor V Shevelev, Kristijan Ramadan, Giuseppe Villani, Silvio Spadari, Ulrich Hübscher, Giovanni Maga Human DNA polymerase lambda diverged ...
2003 Angelo Ranise, Andrea Spallarossa, Silvia Schenone, Olga Bruno, Francesco Bondavalli, Laura Vargiu, Tiziana Marceddu, Massimo Mura, Paolo La Colla, Alessandra Pani Design, synthesis, SAR, and molecular...
2003 Klaus Klumpp, Julie Qi Hang, Surendran Rajendran, Yanli Yang, Andre Derosier, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin Two-metal ion mechanism of RNA cleava...
2003 Yongseok Choi, Clifford George, Maria J Comin, Joseph J Barchi, Hak Sung Kim, Kenneth A Jacobson, Jan Balzarini, Hiroyuki Mitsuya, Paul L Boyer, Stephen H Hughes, Victor E Marquez A conformationally locked analogue of...
2003 Marie-Pierre Golinelli, Stephen H Hughes Secondary structure in the nucleic ac...
2003 Stefania Paolucci, Fausto Baldanti, Marco Tinelli, Giovanni Maga, Giuseppe Gerna Detection of a new HIV-1 reverse tran...
2003 J Gerardo García-Lerma, Hamish MacInnes, Diane Bennett, Patrick Reid, Soumya Nidtha, Hillard Weinstock, Jonathan E Kaplan, Walid Heneine A novel genetic pathway of human immu...
2003 Lingling Shen, Jianhua Shen, Xiaomin Luo, Feng Cheng, Yechun Xu, Kaixian Chen, Edward Arnold, Jianping Ding, Hualiang Jiang Steered molecular dynamics simulation...
2003 Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini Novel human immunodeficiency virus (H...
2003 Marilyn B Kroeger Smith, Sandra Ruby, Stanislav Horouzhenko, Bryan Buckingham, Julia Richardson, Ina Puleri, Emily Potts, William L Jorgensen, Edward Arnold, Weiming Zhang, Stephen H Hughes, Christopher J Michejda, Richard H Smith HIV-1 reverse transcriptase variants:...
2003 Irene M Lagoja, Christophe Pannecouque, Arthur Van Aerschot, Myriam Witvrouw, Zeger Debyser, Jan Balzarini, Piet Herdewijn, Erik De Clercq N-aminoimidazole derivatives inhibiti...
2003 Koyo Ariyoshi, Masakazu Matsuda, Hideka Miura, Sachiko Tateishi, Kaneo Yamada, Wataru Sugiura Patterns of point mutations associate...
2003 Jan Balzarini, Erik De Clercq, Beata Kaminska, Andrzej Orzeszko Synthesis and antiviral activity of s...
2002 Joke Snoeck, Sonia Van Dooren, Kristel Van Laethem, Inge Derdelinckx, Eric Van Wijngaerden, Erik De Clercq, Anne-Mieke Vandamme Prevalence and origin of HIV-1 group ...
2002 Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg Co-receptor usage and HIV-1 intra-cla...
2002 A Geoffrey Skillman, Karl W Maurer, Diana C Roe, Margaret J Stauber, Dolan Eargle, Todd J A Ewing, Angelika Muscate, Elisabeth Davioud-Charvet, Maxine V Medaglia, Robert J Fisher, Edward Arnold, Hong Qiang Gao, Robert W Buckheit, Paul L Boyer, Stephen H Hughes, Irwin D Kuntz, George L Kenyon A novel mechanism for inhibition of H...
2002 Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg Polymorphisms of cytotoxic T-lymphocy...
2002 Bluma G Brenner, Dan Turner, Mark A. Wainberg HIV-1 drug resistance: can we overcome?
2002 Patrick K O'Neil, Guoli Sun, Hong Yu, Yacov Ron, Joseph P Dougherty, Bradley D Preston Mutational analysis of HIV-1 long ter...
2002 R Masciari, L Cosco, M C Diaco, Dora N Della, T Ferraro, T Raimondi, B Ruperti, E Santandrea HIV-1: a case of RT67 deletion in a m...
2002 Brigitte Montes, Michel Segondy Prevalence of the mutational pattern ...
2002 Yven Van Herrewege, Lieve Penne, Chris Vereecken, Katrien Fransen, Guido van der Groen, Luc Kestens, Jan Balzarini, Guido Vanham Activity of reverse transcriptase inh...
2002 Janina Cramer, Michael Strerath, Andreas Marx, Tobias Restle Exploring the effects of active site ... RT,Associated condition,All properties
2002 Timothy S Fisher, Vinayaka R Prasad Substitutions of Phe61 located in the... RT,Associated condition,All properties
2002 Karen S Anderson Perspectives on the molecular mechani... RT,Associated condition,All properties
2002 Christopher J Hollowood, Steven V Ley, Shigeo Yamanoi Synthesis of taurospongin A: a potent...
2002 Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes The M184V mutation reduces the select...
2002 Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes Nucleoside analog resistance caused b...
2002 Robert L Lobato, Eun-Young Kim, Ronald M Kagan, Thomas C Merigan Genotypic and phenotypic analysis of ...
2002 Laurent Andréoletti, Laurence Weiss, Ali Si-Mohamed, Christophe Piketty, Thierry Prazuck, Gérard Calamy, Jean-Elie Malkin, Mathieu Matta, François-Xavier Mbopi-Kéou, François Clavel, Michel D Kazatchkine, Laurent Bélec Multidrug-resistant HIV-1 RNA and pro...
2002 Kirsten L White, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Michael D Miller, Lisa K Naeger Molecular mechanisms of resistance to...
2002 P Richard Harrigan, Mahboob Salim, David K Stammers, Brian Wynhoven, Zabrina L Brumme, Paula McKenna, Brendan A Larder, S D Kemp A mutation in the 3' region of the hu...
2002 Peter R Meyer, Suzanne E Matsuura, Adviye A Tolun, Ingrid Pfeifer, Antero G So, John W Mellors, Walter A Scott Effects of specific zidovudine resist...
2002 Dominique Arion, Nicolas Sluis-Cremer, Kyung-Lyum Min, Michael E Abram, Ronald S Fletcher, Michael A. Parniak Mutational analysis of Tyr-501 of HIV...
2002 Esther Lobatón, Fátima Rodríguez-Barrios, Federico Gago, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez Synthesis of 3' '-substituted TSAO de...
2002 Nobuyuki Kasai, Yoshiyuki Mizushina, Fumio Sugawara, Kengo Sakaguchi Three-dimensional structural model an...
2002 Yoshiyuki Mizushina, Chikako Murakami, Keisuke Ohta, Hirosato Takikawa, Kenji Mori, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi Selective inhibition of the activitie...
2002 Marie-Pierre Golinelli, Stephen H Hughes Nontemplated nucleotide addition by H...
2002 Stefano Aquaro, Raffaele Caliò, Jan Balzarini, Maria Concetta Bellocchi, Enrico Garaci, CF Perno Macrophages and HIV infection: therap...
2002 Jason W Rausch, Daniela Lener, Jennifer T Miller, John G Julias, Stephen H Hughes, Stuart F J Le Grice Altering the RNase H primer grip of h...
2002 Marie-Pierre Golinelli, Stephen H Hughes Nontemplated base addition by HIV-1 R...
2002 Marinela Perpelescu, Jun'ichi Kobayashi, Miho Furuta, Yasutomo Ito, Shunji Izuta, Masaharu Takemura, Motoshi Suzuki, Shonen Yoshida Novel phenalenone derivatives from a ...
2002 N McLellan, Xin Wei, Bruno Marchand, Mark A. Wainberg, Matthias Götte Nonradioactive detection of retrovira...
2002 Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg The M184V mutation in HIV-1 reverse t...
2002 Adrienne M Woodside, F Peter Guengerich Misincorporation and stalling at O(6)...
2002 Adrienne M Woodside, F Peter Guengerich Effect of the O6 substituent on misin...
2002 Adrian S Ray, Aravind Basavapathruni, Karen S Anderson Mechanistic studies to understand the...
2002 Phillip P Chamberlain, Jingshan Ren, Charles E Nichols, L Douglas, Johan Lennerstrand, Brendan A Larder, David I Stuart, David K Stammers Crystal structures of Zidovudine- or ...
2002 Mickael Rigourd, Chantal Ehresmann, Michael A. Parniak, Bernard Ehresmann, Roland Marquet Primer unblocking and rescue of DNA s...
2002 Dimitrios Motakis, Michael A. Parniak A tight-binding mode of inhibition is...
2002 Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak Destabilization of the HIV-1 reverse ...
2002 Joeri Auwerx, Thomas W North, Bradley D Preston, George J Klarmann, Erik De Clercq, Jan Balzarini Chimeric human immunodeficiency virus...
2002 Antonio Mas, Blanca M Vázquez-Alvarez, Esteban Domingo, L Menéndez-Arias Multidrug-resistant HIV-1 reverse tra...
2002 Louis M Mansky HIV mutagenesis and the evolution of ...
2002 Lisa K Naeger, Nicolas A Margot, Michael D Miller ATP-dependent removal of nucleoside r...
2002 John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes Mutations in the RNase H domain of HI...
2002 Jingshan Ren, Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, David I Stuart, David K Stammers Structure of HIV-2 reverse transcript...
2002 L Menéndez-Arias Molecular basis of fidelity of DNA sy...
2002 Janice D Pata, Bradford R King, Thomas A Steitz Assembly, purification and crystalliz...
2002 Qingli Shi, Kamalendra Singh, Aashish Srivastava, Neerja Kaushik, Mukund J Modak Lysine 152 of MuLV reverse transcript...
2002 Stefan G Sarafianos, Arthur D Clark, Kalyan Das, Steve Tuske, Jens J Birktoft, Palanichamy Ilankumaran, Andagar R Ramesha, Jane M Sayer, Donald M Jerina, Paul L Boyer, Stephen H Hughes, Edward Arnold Structures of HIV-1 reverse transcrip...
2002 Michael Strerath, Janina Cramer, Tobias Restle, Andreas Marx Implications of active site constrain...
2002 Fabienne Brulé, Roland Marquet, Liwei Rong, Mark A. Wainberg, Bernard P Roques, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann Structural and functional properties ...
2002 Giuseppe Campiani, Anna Ramunno, Giovanni Maga, Vito Nacci, Caterina Fattorusso, Bruno Catalanotti, Elena Morelli, Ettore Novellino Non-nucleoside HIV-1 reverse transcri...
2002 Giovanni Maga, Silvio Spadari Combinations against combinations: as...
2002 Jimmy Lindberg, Snaevar Sigurdsson, Seved Löwgren, Hans O Andersson, Christer Sahlberg, Rolf Noréen, Kerstin Fridborg, Haijiang Zhang, Torsten Unge Structural basis for the inhibitory e...
2002 Erik De Clercq Highlights in the development of new ...
2002 Erik De Clercq New anti-HIV agents and targets.
2002 Wim Pluymers, Godwin Pais, Bénédicte Van Maele, Christophe Pannecouque, Valery Fikkert, Terrence R Burke, Erik De Clercq, Myriam Witvrouw, Nouri Neamati, Zeger Debyser Inhibition of human immunodeficiency ...
2002 Koen K A Van Rompay, Tim B Matthews, Joanne Higgins, Don R Canfield, Ross P Tarara, Mark A. Wainberg, Raymond F Schinazi, Niels C Pedersen, Thomas W North Virulence and reduced fitness of simi...
2002 Zeger Debyser, Peter Cherepanov, Bénédicte Van Maele, Erik De Clercq, Myriam Witvrouw In search of authentic inhibitors of ...
2002 Christophe Pannecouque, Wim Pluymers, Bénédicte Van Maele, Victor Tetz, Peter Cherepanov, Erik De Clercq, Myriam Witvrouw, Zeger Debyser New class of HIV integrase inhibitors...
2002 Erik De Clercq New developments in anti-HIV chemothe...
2001 Fátima Rodríguez-Barrios, C Pérez, Esther Lobatón, Sonsoles Velázquez, Cristina Chamorro, Ana San-Félix, María-Jesús Pérez-Pérez, María-José Camarasa, H Pelemans, Jan Balzarini, Federico Gago Identification of a putative binding ...
2001 Jan Balzarini, María-José Camarasa, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, CF Perno, Erik De Clercq, J N Anderson, Anna Karlsson Exploitation of the low fidelity of h...
2001 K E Squires An introduction to nucleoside and nuc...
2001 Johan Lennerstrand, Kurt Hertogs, David K Stammers, Brendan A Larder Correlation between viral resistance ...
2001 L Menéndez-Arias, A Abraha, ME Quiñones-Mateu, Antonio Mas, M J Camarasa, E J Arts Functional characterization of chimer...
2001 Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Paul L Boyer, Paul Lewi, Paul A J Janssen, Jörg-Peter Kleim, M Rösner, Stephen H Hughes, Edward Arnold The Lys103Asn mutation of HIV-1 RT: a...
2001 H Pelemans, Robert Esnouf, K L Min, M Parniak, Erik De Clercq, Jan Balzarini Mutations at amino acid positions 63,...
2001 Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes RNase H cleavage of the 5' end of the...
2001 Stephen H Hughes Molecular matchmaking: NNRTIs can enh...
2001 Cristina Chamorro, Esther Lobatón, María-Cruz Bonache, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, Ana San-Félix, María-José Camarasa Identification of a novel family of n...
2001 Jan Balzarini, Erik De Clercq Rapid alternation of drug therapy is ...
2001 Z Sevilya, S Loya, Stephen H Hughes, A Hizi The ribonuclease H activity of the re...
2001 Lisa K Naeger, Michael D Miller Mechanisms of HIV-1 nucleoside revers...
2001 A Martinez, C Gil, A Castro, C Perez, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq Anti-HIV-1 activity of benzothiadiazi...
2001 Donald W Ludovici, Michael J Kukla, P G Grous, S Krishnan, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Erik De Clercq, Edward Arnold, Paul A J Janssen Evolution of anti-HIV drug candidates...
2001 Elena N Peletskaya, Paul L Boyer, Alex A Kogon, Patrick K Clark, Heiko Kroth, Jane M Sayer, Donald M Jerina, Stephen H Hughes Cross-linking of the fingers subdomai...
2001 I A Drachkova, Irina O Petruseva, I V Safronov, A L Zakharenko, G V Shishkin, Olga I Lavrik, Svetlana N Khodyreva [Reagents for modification of protein...
2001 G Tachedjian, M Orlova, Stefan G Sarafianos, Edward Arnold, S P Goff Nonnucleoside reverse transcriptase i...
2001 Phillip A Furman, J Jeffrey, L L Kiefer, Joy Y Feng, Karen S Anderson, K Borroto-Esoda, E Hill, William C Copeland, Chung K Chu, J P Sommadossi, I Liberman, Raymond F Schinazi, George R Painter Mechanism of action of 1-beta-D-2,6-d...
2001 Masanori Kameoka, Liwei Rong, Matthias Götte, Chen Liang, Rodney S Russell, Mark A. Wainberg Role for human immunodeficiency virus...
2001 Donald W Ludovici, Robert W Kavash, Michael J Kukla, Chih Y Ho, Hong Ye, B L De Corte, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, H E Moereels, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Paul J Lewi, Kalyan Das, Edward Arnold, Paul A J Janssen Evolution of anti-HIV drug candidates...
2001 Paul L Boyer, Hong Qiang Gao, Patrick K Clark, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes YADD mutants of human immunodeficienc...
2001 Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes Selective excision of AZTMP by drug-r...
2001 J Y Wang, Hong Ling, Wei Wen Yang, R Craigie Structure of a two-domain fragment of...
2001 Alba Chimirri, Pietro Monforte, Angela Rao, Maria Zappalà, Anna-Maria Monforte, G De Sarro, Christophe Pannecouque, Myriam Witvrouw, Jan Balzarini, Erik De Clercq Synthesis, biological activity, pharm...
2001 J L Hammond, D L Koontz, Holly Z Bazmi, J R Beadle, S E Hostetler, G D Kini, Kathy A Aldern, Douglas D Richman, Karl Y Hostetler, John W Mellors Alkylglycerol prodrugs of phosphonofo...
2001 V Molteni, J Greenwald, D Rhodes, Y Hwang, W Kwiatkowski, F D Bushman, J S Siegel, S Choe Identification of a small-molecule bi...
2001 Erik De Clercq New developments in anti-HIV chemothe...
2001 Jennifer T Miller, Bernard Ehresmann, Ulrich Hübscher, Stuart F J Le Grice A novel interaction of tRNA(Lys,3) wi...
2001 Erik De Clercq, Dominique Schols Inhibition of HIV infection by CXCR4 ...
2001 Taurai Tasara, Giovanni Maga, Michael O Hottiger, Ulrich Hübscher HIV-1 reverse transcriptase and integ...
2001 Giovanni Maga, Anna Ramunno, Vito Nacci, Giada A Locatelli, Silvio Spadari, Isabella Fiorini, Fausto Baldanti, Stefania Paolucci, Maurizio Zavattoni, Alberto Bergamini, Bruno Galletti, S Muck, Ulrich Hubscher, Gianluca Giorgi, G Guiso, S Caccia, Giuseppe Campiani The stereoselective targeting of a sp...
2001 Giuseppe Campiani, F Aiello, M Fabbrini, Elena Morelli, Anna Ramunno, S Armaroli, Vito Nacci, A Garofalo, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, L Ventura, B Bongiovanni, M Capozzi, F Bolacchi, Stefano Marini, Massimo Coletta, G Guiso, S Caccia Quinoxalinylethylpyridylthioureas (QX...
2001 Hiroshi Ohrui, Hiroyuki Mitsuya 4'-C-substituted-2'-deoxynucleosides:...
2001 M Madrid, J A Lukin, J D Madura, Jianping Ding, Edward Arnold Molecular dynamics of HIV-1 reverse t...
2001 Ei-Ichi Kodama, Satoru Kohgo, Kenji Kitano, H Machida, Hiroyuki Gatanaga, S Shigeta, Masao Matsuoka, Hiroshi Ohrui, Hiroyuki Mitsuya 4'-Ethynyl nucleoside analogs: potent...
2001 J E Fitzgibbon, B DiCola, Edward Arnold, Kalyan Das, B E Sha, J C Pottage, R Nahass, S Gaur, J F John HIV-1 reverse transcriptase mutations...
2001 Wim Pluymers, Erik De Clercq, Zeger Debyser HIV-1 integration as a target for ant...
2001 Stefan G Sarafianos, Kalyan Das, C Tantillo, Arthur D Clark, Jianping Ding, J M Whitcomb, Paul L Boyer, Stephen H Hughes, Edward Arnold Crystal structure of HIV-1 reverse tr...
2001 Jingshan Ren, C Nichols, L Bird, P Chamberlain, Kurt L Weaver, S Short, David I Stuart, David K Stammers Structural mechanisms of drug resista...
2001 R Hobi, Ulrich Hübscher, K Neftel, E Alteri, B Poncioni, M R Walker, K Woods-Cook, P Schneider, J K Lazdins Anti-HIV-1 activity in vitro of cefta...
2001 Liwei Rong, Chen Liang, M Hsu, Xiaofeng Guo, Bernard P Roques, Mark A. Wainberg HIV-1 nucleocapsid protein and the se...
2001 Donald W Ludovici, B L De Corte, Michael J Kukla, Hong Ye, Chih Y Ho, Mark A Lichtenstein, Robert W Kavash, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Kalyan Das, Edward Arnold, Paul A J Janssen Evolution of anti-HIV drug candidates...
2001 Li Fan, Laurie S Kaguni Multiple regions of subunit interacti...
2001 G H Kijak, S E Pampuro, M M Avila, C Zala, P Cahn, Mark A. Wainberg, H Salomón Resistance profiles to antiretroviral...
2001 A L Zakharenko, Dmitry M Kolpashchikov, Svetlana N Khodyreva, Olga I Lavrik, L Menéndez-Arias Investigation of the dNTP-binding sit...
2001 M D Driscoll, Marie-Pierre Golinelli, Stephen H Hughes In vitro analysis of human immunodefi...
2001 Paul L Boyer, Hong Qiang Gao, P Frank, Patrick K Clark, Stephen H Hughes The basic loop of the RNase H domain ...
2001 H Pelemans, A Aertsen, Kristel Van Laethem, A-M Vandamme, Erik De Clercq, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, María-José Camarasa, Jan Balzarini Site-directed mutagenesis of human im...
2001 M Lavigne, L Polomack, H Buc Structures of complexes formed by HIV...
2001 M Gutiérrez-Rivas, L Menéndez-Arias A mutation in the primer grip region ...
2001 Joseph H Chan, J S Hong, R N Hunter , G F Orr, Jill R Cowan, D B Sherman, S M Sparks, B E Reitter, C Webster Andrews, Richard J Hazen, M St Clair, Lawrence R Boone, Robert G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, R J Ott, Jingshan Ren, A Hopkins, David I Stuart, David K Stammers 2-Amino-6-arylsulfonylbenzonitriles a...
2001 Matthias Götte, Masanori Kameoka, N McLellan, Luciano Cellai, Mark A. Wainberg Analysis of efficiency and fidelity o...
2001 Catherine Isel, Chantal Ehresmann, P Walter, Bernard Ehresmann, Roland Marquet The emergence of different resistance...
2000 H Pelemans, Robert Esnouf, Erik De Clercq, Jan Balzarini Mutational analysis of trp-229 of hum...
2000 Jan Balzarini Evaluation of Compounds Against Recom...
2000 A-M Vandamme, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Kristel Van Laethem, J C Schmit, J Desmyter, Erik De Clercq Evaluating Clinical Isolates for Thei...
2000 N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg Selection and characterization of hum...
2000 Matthias Götte, Dominique Arion, Michael A. Parniak, Mark A. Wainberg The M184V mutation in the reverse tra...
2000 L T Bacheler, E D Anton, P Kudish, D Baker, J Bunville, K Krakowski, L Bolling, M Aujay, X V Wang, D Ellis, M F Becker, A L Lasut, H J George, D R Spalding, G Hollis, K Abremski Human immunodeficiency virus type 1 m...
2000 V Miller, M Ait-Khaled, C Stone, P Griffin, D Mesogiti, A Cutrell, R Harrigan, Schlomo Staszewski, C Katlama, G Pearce, M Tisdale HIV-1 reverse transcriptase (RT) geno...
2000 A J Brown, H M Precious, Jeannette M Whitcomb, J K Wong, M Quigg, Wei Huang, E S Daar, R T D'Aquila, P H Keiser, E Connick, Nicholas S Hellmann, Christos J Petropoulos, Douglas D Richman, S J Little Reduced susceptibility of human immun...
2000 Kristel Van Laethem, J C Schmit, H Pelemans, Jan Balzarini, Myriam Witvrouw, María-Jesús Pérez-Pérez, María-José Camarasa, R M Esnouf, Stefano Aquaro, A Cenci, CF Perno, P Hermans, S Sprecher, L Ruiz, B Clotet, Eric Van Wijngaerden, M Van Ranst, J Desmyter, Erik De Clercq, A-M Vandamme Presence of 2',5'-Bis-O-(tert-butyldi...
2000 Hong Qiang Gao, Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes The role of steric hindrance in 3TC r...
2000 C de Mendoza, V Soriano, C Briones, O Gallego, P Barreiro, A Alvarez, J González-Lahoz Emergence of zidovudine resistance in...
2000 P Bonfanti, I Faggion, S La Seta Catamancio, M Violin, C Balotta, S Rusconi Response to antiretroviral therapy in...
2000 Dominique Arion, Nicolas Sluis-Cremer, Michael A. Parniak Mechanism by which phosphonoformic ac...
2000 F S Shah, Kenneth A Curr, Monica E Hamburgh, M Parniak, Hiroyuki Mitsuya, J G Arnez, Vinayaka R Prasad Differential influence of nucleoside ...
2000 Christos J Petropoulos, N T Parkin, K L Limoli, Y S Lie, Terri Wrin, Wei Huang, H Tian, D Smith, G A Winslow, D J Capon, Jeannette M Whitcomb A novel phenotypic drug susceptibilit...
2000 Matthias Götte, Mark A. Wainberg Biochemical mechanisms involved in ov...
2000 G J Latham, E Forgacs, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd Vertical-scanning mutagenesis of a cr...
2000 S Najmudin, Marie L Coté, D Sun, S Yohannan, Sherwin P Montano, J Gu, Millie M Georgiadis Crystal structures of an N-terminal f...
2000 Nicolas Sluis-Cremer, G I Dmitrienko, Jan Balzarini, María-José Camarasa, Michael A. Parniak Human immunodeficiency virus type 1 r...
2000 Michael A. Parniak, Nicolas Sluis-Cremer Inhibitors of HIV-1 reverse transcrip...
2000 Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak Molecular mechanisms of HIV-1 resista...
2000 E P Coakley, J M Gillis, S M Hammer Phenotypic and genotypic resistance p...
2000 Neerja Kaushik, T T Talele, P K Pandey, D Harris, P N Yadav, V N Pandey Role of glutamine 151 of human immuno...
2000 Nicolas Sluis-Cremer, Dominique Arion, Neerja Kaushik, H Lim, Michael A. Parniak Mutational analysis of Lys65 of HIV-1...
2000 K K Weiss, S J Isaacs, N H Tran, Elinor T Adman, Baek Kim Molecular architecture of the mutagen...
2000 C E Cases-Gonzalez, M Gutierrez-Rivas, L Menéndez-Arias Coupling ribose selection to fidelity...
2000 Lawrence A Loeb, J I Mullins Lethal mutagenesis of HIV by mutageni...
2000 H Salomon, Mark A. Wainberg, Bluma G Brenner, Yudong Quan, D Rouleau, P Coté, R LeBlanc, E Lefebvre, Bonnie Spira, C Tsoukas, Rafick-Pierre Sekaly, Brian Conway, D Mayers, Jean-Pierre Routy Prevalence of HIV-1 resistant to anti...
2000 A Khorchid, H Javanbakht, S Wise, R Halwani, Michael A. Parniak, Mark A. Wainberg, Lawrence Kleiman Sequences within Pr160gag-pol affecti...
2000 Bluma G Brenner, Mark A. Wainberg, H Salomon, D Rouleau, A Dascal, Bonnie Spira, Rafick-Pierre Sekaly, Brian Conway, Jean-Pierre Routy Resistance to antiretroviral drugs in...
2000 N Richard, H Salomon, Maureen Oliveira, R Rando, T Mansour, Z Gu, Mark A. Wainberg Selection of resistance-conferring mu...
2000 Paul L Boyer, Stephen H Hughes Effects of amino acid substitutions a...
2000 L Mu, Stefan G Sarafianos, Marc C Nicklaus, P Russ, Maqbool A Siddiqui, H Ford, Hiroyuki Mitsuya, R Le, Eiichi N Kodama, Chris Meier, T Knispel, L Anderson, Joseph J Barchi, Victor E Marquez Interactions of conformationally bias...
2000 Jingshan Ren, C Nichols, Louise E Bird, Tsuyoshi Fujiwara, H Sugimoto, David I Stuart, David K Stammers Binding of the second generation non-...
2000 Jingshan Ren, John Milton, Kurt L Weaver, Steven A Short, David I Stuart, David K Stammers Structural basis for the resilience o...
2000 Giuseppe Campiani, M Fabbrini, Elena Morelli, Vito Nacci, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, C Fracasso, S Caccia Non-nucleoside HIV-1 reverse transcri...
2000 K Nozawa, Motoshi Suzuki, Masaharu Takemura, Shonen Yoshida In vitro expansion of mammalian telom...
2000 Mickael Rigourd, J M Lanchy, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann, Roland Marquet Inhibition of the initiation of HIV-1...
2000 W R Davis, J Tomsho, S Nikam, E M Cook, D Somand, J A Peliska Inhibition of HIV-1 reverse transcrip...
2000 Ming Yu, W Kabat, Jian Wang [Rapid detection of drug resistant HI...
2000 T Imamichi, T Sinha, H Imamichi, Y M Zhang, J A Metcalf, J Falloon, H C Lane High-level resistance to 3'-azido-3'-...
2000 Neerja Kaushik, K Chowdhury, V N Pandey, Mukund J Modak Valine of the YVDD motif of moloney m...
2000 D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando Drug resistance and drug combination ...
2000 Myriam Witvrouw, Valery Fikkert, Wim Pluymers, B Matthews, K Mardel, Dominique Schols, J Raff, Zeger Debyser, Erik De Clercq, G Holan, Christophe Pannecouque Polyanionic (i.e., polysulfonate) den...
2000 A Casimiro-Garcia, Erik De Clercq, Christophe Pannecouque, Myriam Witvrouw, T L Stup, J A Turpin, Robert W Buckheit, Mark Cushman Synthesis and anti-HIV activity of co...
2000 Erik De Clercq Current lead natural products for the...
2000 Holly Z Bazmi, J L Hammond, S C Cavalcanti, Chung K Chu, Raymond F Schinazi, John W Mellors In vitro selection of mutations in th...
2000 K Van Vaerenbergh, Kristel Van Laethem, J Albert, Charles A B Boucher, B Clotet, M Floridia, J Gerstoft, B Hejdeman, C Nielsen, Christophe Pannecouque, L Perrin, M F Pirillo, L Ruiz, J C Schmit, F Schneider, A Schoolmeester, Rob Schuurman, H J Stellbrink, L Stuyver, J Van Lunzen, Barbara Van Remoortel, Eric Van Wijngaerden, S Vella, Myriam Witvrouw, Sabine Yerly, Erik De Clercq, J Destmyer, Anne-Mieke Vandamme Prevalence and characteristics of mul...
2000 Kamalendra Singh, Neerja Kaushik, J Jin, M Madhusudanan, Mukund J Modak Role of Q190 of MuLV RT in ddNTP resi...
2000 Myriam Witvrouw, Christophe Pannecouque, J Desmyter, Erik De Clercq, Koen Andries In vitro evaluation of the effect of ...
2000 H Jonckheere, Erik De Clercq, J Anné Fidelity analysis of HIV-1 reverse tr...
2000 H Jonckheere, J Anné, Erik De Clercq The HIV-1 reverse transcription (RT) ...
2000 Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes Analysis of mutations at positions 11...
2000 Jan Balzarini, Erik De Clercq, A Carbonez, V Burt, Jörg-Peter Kleim Long-term exposure of HIV type 1-infe...
2000 Antonio Mas, M Parera, C Briones, V Soriano, Miguel Angel Martínez, Esteban Domingo, L Menéndez-Arias Role of a dipeptide insertion between...
2000 Peter R Meyer, Suzanne E Matsuura, Raymond F Schinazi, Antero G So, Walter A Scott Differential removal of thymidine nuc...
2000 Jingshan Ren, J Diprose, J Warren, R M Esnouf, Louise E Bird, Shinji Ikemizu, M Slater, John Milton, Jan Balzarini, David I Stuart, David K Stammers Phenylethylthiazolylthiourea (PETT) n...
2000 T V Rao, M T Haber, Jane M Sayer, Donald M Jerina Incorporation of 4-thiothymidine into...
2000 Kurt Hertogs, Stuart Bloor, V De Vroey, C van Den Eynde, Pascale Dehertogh, A van Cauwenberge, Martin Stürmer, T Alcorn, S Wegner, M van Houtte, V Miller, Brendan A Larder A novel human immunodeficiency virus ...
2000 P Richard Harrigan, C Stone, P Griffin, I Nájera, Stuart Bloor, S Kemp, M Tisdale, Brendan A Larder Resistance profile of the human immun...
1999 M Madrid, A Jacobo-Molina, Jianping Ding, Edward Arnold Major subdomain rearrangement in HIV-...
1999 M E Arranz, J A Díaz, S T Ingate, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, S Vega Synthesis and anti-HIV activity of 1,...
1999 Andrew L Hopkins, Jingshan Ren, Hiromichi Tanaka, Masanori Baba, M Okamato, David I Stuart, David K Stammers Design of MKC-442 (emivirine) analogu...
1999 Jingshan Ren, R M Esnouf, Andrew L Hopkins, David I Stuart, David K Stammers Crystallographic analysis of the bind...
1999 Neerja Kaushik, Kamalendra Singh, I Alluru, Mukund J Modak Tyrosine 222, a member of the YXDD mo...
1999 Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari Molecular basis for the enantioselect...
1999 Junxing Shi, J J McAtee, S Schlueter Wirtz, P Tharnish, A Juodawlkis, Dennis C Liotta, Raymond F Schinazi Synthesis and biological evaluation o...
1999 Thomas A Steitz DNA polymerases: structural diversity...
1999 Paul L Boyer, J Lisziewicz, F Lori, Stephen H Hughes Analysis of amino insertion mutations...
1999 L L Furge, F Peter Guengerich Explanation of pre-steady-state kinet...
1999 Yudong Quan, Dimitrios Motakis, R Buckheit, Z Q Xu, M T Flavin, Michael A. Parniak, Mark A. Wainberg Sensitivity and resistance to (+)-cal...
1999 Z Gu, Mark A. Wainberg, N Nguyen-Ba, L L'Heureux, J M de Muys, T L Bowlin, R F Rando Mechanism of action and in vitro acti...
1999 J M de Muys, H Gourdeau, N Nguyen-Ba, D L Taylor, P S Ahmed, T Mansour, C Locas, N Richard, Mark A. Wainberg, R F Rando Anti-human immunodeficiency virus typ...
1999 Brendan A Larder, Stuart Bloor, S D Kemp, Kurt Hertogs, R L Desmet, V Miller, M Sturmer, Schlomo Staszewski, Jingshan Ren, David K Stammers, David I Stuart, Rudi Pauwels A family of insertion mutations betwe...
1999 Yudong Quan, Liwei Rong, Chen Liang, Mark A. Wainberg Reverse transcriptase inhibitors can ...
1999 H Rübsamen-Waigmann, E Huguenel, A Shah, A Paessens, H J Ruoff, H von Briesen, A Immelmann, U Dietrich, Mark A. Wainberg Resistance mutations selected in vivo...
1999 S Cen, Yangxin Huang, A Khorchid, J L Darlix, Mark A. Wainberg, Lawrence Kleiman The role of Pr55(gag) in the annealin...
1999 G Borkow, Dominique Arion, Mark A. Wainberg, Michael A. Parniak The thiocarboxanilide nonnucleoside i...
1999 Stefan G Sarafianos, Kalyan Das, Arthur D Clark, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold Lamivudine (3TC) resistance in HIV-1 ...
1999 Lawrence A Loeb, J M Essigmann, F Kazazi, Jun Zhang, K D Rose, J I Mullins Lethal mutagenesis of HIV with mutage...
1999 P F Lin, C J González, B Griffith, G Friedland, V Calvez, F Ferchal, Raymond F Schinazi, D H Shepp, A B Ashraf, Mark A. Wainberg, V Soriano, John W Mellors, R J Colonno Stavudine resistance: an update on su...
1999 Katarzyna Bebenek, J C Boyer, Thomas A Kunkel The base substitution fidelity of HIV...
1999 M Wisniewski, C Palaniappan, Z Fu, Stuart F J Le Grice, P Fay, Robert A Bambara Mutations in the primer grip region o...
1999 M D Powell, William A Beard, Katarzyna Bebenek, K J Howard, Stuart F J Le Grice, Thomas A Darden, Thomas A Kunkel, Samuel H Wilson, J G Levin Residues in the alphaH and alphaI hel...
1999 Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi Action of a new mammalian DNA polymer...
1999 Dominique Arion, Michael A. Parniak HIV resistance to zidovudine: the rol...
1999 Peter R Meyer, Suzanne E Matsuura, A M Mian, Antero G So, Walter A Scott A mechanism of AZT resistance: an inc...
1999 Matthias Götte, Xincang Li, Mark A. Wainberg HIV-1 reverse transcription: a brief ...
1999 Mark A. Wainberg, Michael D Miller, Yudong Quan, H Salomon, A S Mulato, P D Lamy, Nicolas A Margot, K E Anton, J M Cherrington In vitro selection and characterizati...
1999 N Richar, Yudong Quan, H Salomon, M Hsu, J Bedard, P Richard Harrigan, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg Selection and characterization of HIV...
1999 D A Lewis, Katarzyna Bebenek, William A Beard, Samuel H Wilson, Thomas A Kunkel Uniquely altered DNA replication fide...
1999 J Izopet, A Bicart-See, C Pasquier, K Sandres, E Bonnet, B Marchou, J Puel, P Massip Mutations conferring resistance to zi...
1999 I Pellegrin, J Izopet, J Reynes, M Denayrolles, Brigitte Montes, J L Pellegrin, P Massip, J Puel, H Fleury, Michel Segondy Emergence of zidovudine and multidrug...
1999 H Idriss, S Kawa, Z Damuni, E B Thompson, Samuel H Wilson HIV-1 reverse transcriptase is phosph...
1999 A Rakik, M Ait-Khaled, P Griffin, T A Thomas, M Tisdale, Jörg-Peter Kleim A novel genotype encoding a single am...
1999 Baek Kim, J C Ayran, S G Sagar, Elinor T Adman, S M Fuller, N H Tran, J Horrigan New human immunodeficiency virus, typ...
1999 Alexandra Vaisman, Susan E Lim, S M Patrick, William C Copeland, David C Hinkle, J J Turchi, Stephen G Chaney Effect of DNA polymerases and high mo...
1999 Zucai Suo, S J Lippard, Kenneth A Johnson Single d(GpG)/cis-diammineplatinum(II...
1999 Stefan G Sarafianos, Kalyan Das, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold Touching the heart of HIV-1 drug resi...
1999 Matthias Götte, G Maier, A M Onori, Luciano Cellai, Mark A. Wainberg, H Heumann Temporal coordination between initiat...
1999 Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes Similarities and differences in the R...
1999 Sylvie Doublié, M R Sawaya, Tom Ellenberger An open and closed case for all polym...
1999 Y Goldgur, R Craigie, G H Cohen, Tsuyoshi Fujiwara, T Yoshinaga, T Fujishita, H Sugimoto, T Endo, H Murai, D R Davies Structure of the HIV-1 integrase cata...
1999 T Szyperski, Matthias Götte, M Billeter, E Perola, Luciano Cellai, H Heumann, K Wüthrich NMR structure of the chimeric hybrid ...
1999 Jan Balzarini Suppression of resistance to drugs ta...
1999 J J de Jong, J Goudsmit, V V Lukashov, M E Hillebrand, E Baan, R Huismans, Sven A Danner, J H ten Veen, F de Wolf, Suzanne Jurriaans Insertion of two amino acids combined...
1999 Sonsoles Velázquez, V Tuñón, M L Jimeno, Cristina Chamorro, Erik De Clercq, Jan Balzarini, María-José Camarasa Potential multifunctional inhibitors ...
1999 Myriam Witvrouw, Christophe Pannecouque, Erik De Clercq, E Fernández-Alvarez, J L Marco Inhibition of human immunodeficiency ...
1999 Michael D Miller, K E Anton, A S Mulato, P D Lamy, J M Cherrington Human immunodeficiency virus type 1 e...
1999 Myriam Witvrouw, Christophe Pannecouque, Kristel Van Laethem, J Desmyter, Erik De Clercq, Anne-Mieke Vandamme Activity of non-nucleoside reverse tr...
1999 Taurai Tasara, Mario Amacker, Ulrich Hübscher Intramolecular chimeras of the p51 su...
1999 Andreas Marx, M Spichty, Mario Amacker, U Schwitter, Ulrich Hübscher, Thomas A Bickle, Giovanni Maga, Bernd Giese Probing interactions between HIV-1 re...
1999 Giuseppe Campiani, Elena Morelli, M Fabbrini, Vito Nacci, Giovanni Greco, Ettore Novellino, Anna Ramunno, Giovanni Maga, Silvio Spadari, G Caliendo, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, A Nacca, S Caccia Pyrrolobenzoxazepinone derivatives as...
1999 Joy Y Feng, Karen S Anderson Mechanistic studies comparing the inc...
1999 M Högberg, Christer Sahlberg, P Engelhardt, Rolf Noréen, J Kangasmetsä, N G Johansson, Bo Oberg, L Vrang, Haijiang Zhang, B L Sahlberg, Torsten Unge, S Lövgren, Kerstin Fridborg, K Bäckbro Urea-PETT compounds as a new class of...
1998 Tsuyoshi Fujiwara, Akira Sato, M el-Farrash, S Miki, K Abe, Y Isaka, M Kodama, Y Wu, L B Chen, H Harada, H Sugimoto, Masami Hatanaka, Y Hinuma S-1153 inhibits replication of known ...
1998 A Acel, B E Udashkin, Mark A. Wainberg, E A Faust Efficient gap repair catalyzed in vit...
1998 F J Palella, K M Delaney, A C Moorman, M O Loveless, J Fuhrer, G A Satten, D J Aschman, S D Holmberg Declining morbidity and mortality amo...
1998 C Tamalet, J Izopet, N Koch, J Fantini, N Yahi Stable rearrangements of the beta3-be...
1998 C Katlama, M A Valantin, S Matheron, A Coutellier, V Calvez, D Descamps, C Longuet, M Bonmarchand, R Tubiana, M De Sa, R Lancar, Henri Agut, F Brun-Vezinet, D Costagliola Efficacy and tolerability of stavudin...
1998 Akitsu Ogawa, Takashi Murate, Shunji Izuta, Masaharu Takemura, Kyoji Furuta, Jun'ichi Kobayashi, T Kamikawa, Y Nimura, Shonen Yoshida Sulfated glycoglycerolipid from archa...
1998 Zucai Suo, Kenneth A Johnson Selective inhibition of HIV-1 reverse...
1998 Zucai Suo, Kenneth A Johnson DNA secondary structure effects on DN...
1998 Monica E Hamburgh, William C Drosopoulos, Vinayaka R Prasad The influence of 3TC-resistance mutat...
1998 Jianping Ding, Kalyan Das, Y Hsiou, Stefan G Sarafianos, Arthur D Clark, A Jacobo-Molina, C Tantillo, Stephen H Hughes, Edward Arnold Structure and functional implications...
1998 Hao Huang, R Chopra, G L Verdine, S C Harrison Structure of a covalently trapped cat...
1998 Jingshan Ren, R M Esnouf, Andrew L Hopkins, J Warren, Jan Balzarini, David I Stuart, David K Stammers Crystal structures of HIV-1 reverse t...
1998 Jingshan Ren, R M Esnouf, Andrew L Hopkins, E Yvonne Jones, I Kirby, J Keeling, C K Ross, Brendan A Larder, David I Stuart, David K Stammers 3'-Azido-3'-deoxythymidine drug resis...
1998 Joachim Jaeger, Tobias Restle, Thomas A Steitz The structure of HIV-1 reverse transc...
1998 Y Hsiou, Kalyan Das, Jianping Ding, Arthur D Clark, Jörg-Peter Kleim, M Rösner, I Winkler, G Riess, Stephen H Hughes, Edward Arnold Structures of Tyr188Leu mutant and wi...
1998 S W Graves, Allison A Johnson, Kenneth A Johnson Expression, purification, and initial... Processivity,Kd,Vmax,All properties
1998 Baek Kim, T R Hathaway, Lawrence A Loeb Fidelity of mutant HIV-1 reverse tran...
1998 D Harris, P N Yadav, V N Pandey Loss of polymerase activity due to Ty...
1998 D Harris, Neerja Kaushik, P K Pandey, P N Yadav, V N Pandey Functional analysis of amino acid res...
1998 Matthias Götte, G Maier, H J Gross, H Heumann Localization of the active site of HI...
1998 G Tachedjian, John W Mellors, H Bazmi, J Mills Impaired fitness of foscarnet-resista...
1998 Dominique Arion, Neerja Kaushik, Suzanne McCormick, G Borkow, Michael A. Parniak Phenotypic mechanism of HIV-1 resista...
1998 Bruno Canard, S R Sarfati, Charles C Richardson Enhanced binding of azidothymidine-re...
1998 Peter R Meyer, Suzanne E Matsuura, Antero G So, Walter A Scott Unblocking of chain-terminated primer...
1998 Joseph A Vaccaro, Karen S Anderson Implication of the tRNA initiation st...
1998 M A Winters, K L Coolley, Y A Girard, D J Levee, H Hamdan, R W Shafer, D A Katzenstein, T C Merigan A 6-basepair insert in the reverse tr...
1998 Michael D Miller, P D Lamy, M D Fuller, A S Mulato, Nicolas A Margot, T Cihlar, J M Cherrington Human immunodeficiency virus type 1 r...
1998 Mark Cushman, A Casimiro-Garcia, E Hejchman, J A Ruell, M Huang, C A Schaeffer, K Williamson, W G Rice, Robert W Buckheit New alkenyldiarylmethanes with enhanc...
1998 L M Demeter, P M Meehan, G Morse, M A Fischl, M Para, W Powderly, J Leedom, J Holden-Wiltse, C Greisberger, K Wood, J Timpone, L K Wathen, T Nevin, L Resnick, D H Batts, R C Reichman Phase I study of atevirdine mesylate ...
1998 Myriam Witvrouw, M E Arranz, Christophe Pannecouque, R Declercq, H Jonckheere, J C Schmit, A-M Vandamme, J A Diaz, S T Ingate, J Desmyter, Robert Esnouf, L Van Meervelt, S Vega, Jan Balzarini, Erik De Clercq 1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,...
1998 H Pelemans, R M Esnouf, Michael A. Parniak, A-M Vandamme, Erik De Clercq, Jan Balzarini A proline-to-histidine substitution a...
1998 H Togashi, Yoshiyuki Mizushina, Masaharu Takemura, Fumio Sugawara, Hiroyuki Koshino, Y Esumi, J Uzawa, H Kumagai, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi 4-Hydroxy-17-methylincisterol, an inh...
1998 Yoshiyuki Mizushina, L Hanashima, Tsuyoshi Yamaguchi, Masaharu Takemura, Fumio Sugawara, Mineo Saneyoshi, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi A mushroom fruiting body-inducing sub...
1998 Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi Sulfoquinovosyldiacylglycerol, KM043,...
1998 M Nakayabu, S Miwa, Motoshi Suzuki, Shunji Izuta, G Sobue, Shonen Yoshida Mismatched nucleotides may facilitate...
1998 H J Einolf, N Schnetz-Boutaud, F Peter Guengerich Steady-state and pre-steady-state kin...
1998 Silvio Spadari, Giovanni Maga, A Verri, Federico Focher Molecular basis for the antiviral and...
1998 William A Beard, Katarzyna Bebenek, Thomas A Darden, Lin Li, Rajendra Prasad, Thomas A Kunkel, Samuel H Wilson Vertical-scanning mutagenesis of a cr...
1998 I Choudhury, Jianhong Wang, A B Rabson, S Stein, S Pooyan, S Stein, M J Leibowitz Inhibition of HIV-1 replication by a ...
1998 Andreas Marx, Mario Amacker, M Stucki, Ulrich Hübscher, Thomas A Bickle, Bernd Giese 4'-Acylated thymidine 5'-triphosphate...
1998 M von Janta-Lipinski, B Costisella, H Ochs, Ulrich Hübscher, P Hafkemeyer, E Matthes Newly synthesized L-enantiomers of 3'...
1998 Mario Amacker, Ulrich Hübscher Chimeric HIV-1 and feline immunodefic...
1998 Hong Qiang Gao, Paul L Boyer, Edward Arnold, Stephen H Hughes Effects of mutations in the polymeras...
1998 D V Nissley, Paul L Boyer, D J Garfinkel, Stephen H Hughes, J N Strathern Hybrid Ty1/HIV-1 elements used to det...
1998 Paul L Boyer, Hong Qiang Gao, Stephen H Hughes A mutation at position 190 of human i...
1998 Yudong Quan, P Inouye, Chen Liang, Liwei Rong, Matthias Götte, Mark A. Wainberg Dominance of the E89G substitution in...
1998 H Salomon, Julio S G Montaner, A Belmonte, Mark A. Wainberg Diminished HIV-1 sensitivity to stavu...
1998 Yudong Quan, Chen Liang, P Inouye, Mark A. Wainberg Enhanced impairment of chain elongati...
1998 E Cherry, Chen Liang, Liwei Rong, Yudong Quan, P Inouye, Xincang Li, N Morin, M Kotler, Mark A. Wainberg Characterization of human immunodefic...
1998 William C Drosopoulos, Lisa F Rezende, Mark A. Wainberg, Vinayaka R Prasad Virtues of being faithful: can we lim...
1998 E Cherry, N Morin, Mark A. Wainberg Effect of HIV constructs containing p...
1998 P Inouye, E Cherry, M Hsu, S Zolla-Pazner, Mark A. Wainberg Neutralizing antibodies directed agai...
1998 Yudong Quan, Z Gu, Xincang Li, Chen Liang, Michael A. Parniak, Mark A. Wainberg Endogenous reverse transcriptase assa...
1998 H Kwon, N Pelletier, C DeLuca, P Genin, S Cisternas, R Lin, Mark A. Wainberg, J Hiscott Inducible expression of IkappaBalpha ...
1998 M Wasner, Dominique Arion, G Borkow, A Noronha, A H Uddin, Michael A. Parniak, Masad J Damha Physicochemical and biochemical prope...
1998 Cristina Chamorro, María-José Camarasa, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, Ana San Félix An approach towards the synthesis of ...
1998 Sonsoles Velázquez, Cristina Chamorro, María-Jesús Pérez-Pérez, R Alvarez, M L Jimeno, A Martín-Domenech, C Pérez, Federico Gago, Erik De Clercq, Jan Balzarini, Ana San-Félix, María-José Camarasa Abasic analogues of TSAO-T as the fir...
1998 Erik De Clercq The role of non-nucleoside reverse tr...
1998 J C Schmit, L Ruiz, L Stuyver, Kristel Van Laethem, I Vanderlinden, T Puig, R Rossau, J Desmyter, Erik De Clercq, B Clotet, A-M Vandamme Comparison of the LiPA HIV-1 RT test,...
1998 Erik De Clercq New perspectives for the treatment of...
1998 H Jonckheere, Myriam Witvrouw, Erik De Clercq, J Anné Lamivudine resistance of HIV type 1 d...
1998 Kamalendra Singh, Mukund J Modak A unified DNA- and dNTP-binding mode ...
1997 Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, Koen Andries, Robert W Buckheit, Richard H Smith Molecular modeling of HIV-1 reverse t...
1997 Robert W Buckheit, M J Snow, V Fliakas-Boltz, T L Kinjerski, J D Russell, L A Pallansch, W G Brouwer, S S Yang Highly potent oxathiin carboxanilide ...
1997 E Forgacs, G Latham, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd Probing structure/function relationsh...
1997 Myriam Witvrouw, Jan Balzarini, Christophe Pannecouque, S Jhaumeer-Laulloo, J A Esté, Dominique Schols, Peter Cherepanov, J C Schmit, Zeger Debyser, A-M Vandamme, J Desmyter, S R Ramadas, Erik De Clercq SRR-SB3, a disulfide-containing macro...
1997 Jianping Ding, Stephen H Hughes, Edward Arnold Protein-nucleic acid interactions and...
1997 H Pelemans, Robert Esnouf, A Dunkler, Michael A. Parniak, A-M Vandamme, Anna Karlsson, Erik De Clercq, Jörg-Peter Kleim, Jan Balzarini Characteristics of the Pro225His muta...
1997 Jörg-Peter Kleim, I Winkler, M Rösner, R Kirsch, H Rübsamen-Waigmann, A Paessens, G Riess In vitro selection for different muta...
1997 Stefano Aquaro, CF Perno, Emanuela Balestra, Jan Balzarini, A Cenci, M Francesconi, S Panti, F Serra, N Villani, Raffaele Caliò Inhibition of replication of HIV in p...
1997 Jan Balzarini, H Pelemans, G Riess, M Roesner, I Winkler, Erik De Clercq, Jörg-Peter Kleim Zidovudine-resistant human immunodefi...
1997 Erik De Clercq Development of resistance of human im...
1997 Erik De Clercq In search of a selective antiviral ch...
1997 M Tanaka, R V Srinivas, Takayuki Ueno, M F Kavlick, F K Hui, A Fridland, J S Driscoll, Hiroyuki Mitsuya In vitro induction of human immunodef...
1997 Yoshiyuki Mizushina, Shonen Yoshida, Akio Matsukage, Kengo Sakaguchi The inhibitory action of fatty acids ...
1997 L L Furge, F Peter Guengerich Analysis of nucleotide insertion and ...
1997 A De Antoni, A Foli, J Lisziewicz, F Lori Mutations in the pol gene of human im...
1997 Giovanni Maga, Mario Amacker, N Ruel, Ulrich Hübscher, Silvio Spadari Resistance to nevirapine of HIV-1 rev...
1997 I V Safronov, N V Shcherbik, Svetlana N Khodyreva, V A Vlasov, M I Dobrikov, G V Shishkin, Olga I Lavrik [New photoreactive N(4)-substituted d...
1997 Myriam Witvrouw, Erik De Clercq Sulfated polysaccharides extracted fr...
1997 H Hara, T Fujihashi, T Sakata, A Kaji, H Kaji Tetrahydronaphthalene lignan compound...
1997 B P Burnett, Charles S McHenry Posttranscriptional modification of r...
1997 Bruno Canard, R Sarfati, Charles C Richardson Binding of RNA template to a complex ...
1997 W Keulen, N K Back, A van Wijk, Charles A B Boucher, Ben Berkhout Initial appearance of the 184Ile vari...
1997 A Hizi, Ashwini S Kamath-Loeb, K D Rose, Lawrence A Loeb Mutagenesis by human immunodeficiency...
1997 Ashwini S Kamath-Loeb, A Hizi, Hironori Kasai, Lawrence A Loeb Incorporation of the guanosine tripho...
1997 G Borkow, Dominique Arion, A Noronha, M Scartozzi, Masad J Damha, Michael A. Parniak Inhibitory potency of R-region specif...
1997 M Hsu, P Inouye, L Rezende, N Richard, Zhongjie Li, Vinayaka R Prasad, Mark A. Wainberg Higher fidelity of RNA-dependent DNA ...
1997 Chen Liang, Liwei Rong, N Morin, E Cherry, Yangxin Huang, Lawrence Kleiman, Mark A. Wainberg The roles of the human immunodeficien...
1997 F Lori, A G Malykh, A Foli, R Maserati, A De Antoni, L Minoli, D Padrini, A Degli Antoni, E Barchi, H Jessen, Mark A. Wainberg, R C Gallo, J Lisziewicz Combination of a drug targeting the c...
1997 Chen Liang, Xincang Li, Liwei Rong, P Inouye, Yudong Quan, Lawrence Kleiman, Mark A. Wainberg The importance of the A-rich loop in ...
1997 Mark A. Wainberg Increased fidelity of drug-selected M...
1997 J Mak, A Khorchid, Q Cao, Yangxin Huang, I Lowy, Michael A. Parniak, Vinayaka R Prasad, Mark A. Wainberg, Lawrence Kleiman Effects of mutations in Pr160gag-pol ...
1997 M D Powell, M Ghosh, P S Jacques, K J Howard, Stuart F J Le Grice, J G Levin Alanine-scanning mutations in the "pr...
1997 C Palaniappan, M Wisniewski, P S Jacques, Stuart F J Le Grice, P J Fay, Robert A Bambara Mutations within the primer grip regi...
1997 Neerja Kaushik, D Harris, N Rege, Mukund J Modak, P N Yadav, V N Pandey Role of glutamine-151 of human immuno...
1997 G Gao, M Orlova, Millie M Georgiadis, W A Hendrickson, S P Goff Conferring RNA polymerase activity to...
1997 Jan Balzarini, Erik De Clercq, K Uberla SIV/HIV-1 hybrid virus expressing the...
1997 R M Esnouf, David I Stuart, Erik De Clercq, E Schwartz, Jan Balzarini Models which explain the inhibition o...
1997 J Barnard, G Borkow, Michael A. Parniak The thiocarboxanilide nonnucleoside U...
1997 M Tisdale, T Alnadaf, D Cousens Combination of mutations in human imm...
1997 Takayuki Ueno, Hiroyuki Mitsuya Comparative enzymatic study of HIV-1 ...
1997 T Rubinek, M Bakhanashvili, R Taube, O Avidan, A Hizi The fidelity of 3' misinsertion and m...
1997 S Loya, Hong Qiang Gao, O Avidan, Paul L Boyer, Stephen H Hughes, A Hizi Subunit-specific mutagenesis of the c...
1997 Y M Lin, H Anderson, M T Flavin, Y H Pai, E Mata-Greenwood, T Pengsuparp, J M Pezzuto, Raymond F Schinazi, Stephen H Hughes, F C Chen In vitro anti-HIV activity of biflavo...
1997 S G Kerr, Karen S Anderson Pre-steady-state kinetic characteriza...
1997 G Borkow, Ronald S Fletcher, J Barnard, Dominique Arion, Dimitrios Motakis, G I Dmitrienko, Michael A. Parniak Inhibition of the ribonuclease H and ...
1997 G Borkow, J Barnard, T M Nguyen, A Belmonte, Mark A. Wainberg, Michael A. Parniak Chemical barriers to human immunodefi...
1997 R Krebs, U Immendörfer, S H Thrall, B M Wöhrl, R S Goody Single-step kinetics of HIV-1 reverse...
1997 R M Esnouf, Jingshan Ren, Andrew L Hopkins, C K Ross, E Yvonne Jones, David K Stammers, David I Stuart Unique features in the structure of t...
1997 W Tong, C D Lu, S K Sharma, S Matsuura, Antero G So, Walter A Scott Nucleotide-induced stable complex for...
1997 Zucai Suo, Kenneth A Johnson Effect of RNA secondary structure on ...
1997 Zucai Suo, Kenneth A Johnson RNA secondary structure switching dur...
1997 Zucai Suo, Kenneth A Johnson Effect of RNA secondary structure on ...
1997 M A Winters, R W Shafer, R A Jellinger, G Mamtora, T Gingeras, T C Merigan Human immunodeficiency virus type 1 r...
1997 Mario Amacker, M Hottiger, R Mossi, Ulrich Hübscher HIV-1 nucleocapsid protein and replic...
1997 Thomas Roth, Marshall L Morningstar, Paul L Boyer, Stephen H Hughes, Robert W Buckheit, Christopher J Michejda Synthesis and biological activity of ...
1996 T Pengsuparp, M Serit, Stephen H Hughes, D D Soejarto, J M Pezzuto Specific inhibition of human immunode...
1996 Zeger Debyser, Erik De Clercq Chemical crosslinking of the subunits...
1996 Rudi Pauwels, Erik De Clercq Development of vaginal microbicides f...
1996 M G Davis, J E Wilson, N A VanDraanen, W H Miller, George A Freeman, S M Daluge, F L Boyd, A E Aulabaugh, George R Painter, Lawrence R Boone DNA polymerase activity of hepatitis ...
1996 B M Moore, Ke Li, Michael B Doughty Deoxyadenosine-based DNA polymerase p...
1996 Mark A. Wainberg, M Hsu, Z Gu, G Borkow, Michael A. Parniak Effectiveness of 3TC in HIV clinical ...
1996 Zhongjie Li, A Shalom, Yangxin Huang, J Mak, E Arts, Mark A. Wainberg, Lawrence Kleiman Multiple forms of tRNA(Lys3) in HIV-1.
1996 Dominique Arion, R Harada, Xincang Li, Mark A. Wainberg, Michael A. Parniak HIV-1 reverse transcriptase shows no ...
1996 Neerja Kaushik, N Rege, P N Yadav, Stefan G Sarafianos, Mukund J Modak, V N Pandey Biochemical analysis of catalytically...
1996 Jörg-Peter Kleim, M Rösner, I Winkler, A Paessens, R Kirsch, Y Hsiou, Edward Arnold, G Riess Selective pressure of a quinoxaline n...
1996 M Hottiger, Ulrich Hübscher Human Immunodeficiency Virus type 1 r...
1996 D L Winslow, S Garber, C Reid, H Scarnati, D Baker, M M Rayner, E D Anton Selection conditions affect the evolu...
1996 Jan Balzarini, W G Brouwer, D C Dao, E M Osika, Erik De Clercq Identification of novel thiocarboxani...
1996 Xincang Li, Yudong Quan, E.J. Arts, Zhongjie Li, Bradley D Preston, H de Rocquigny, Bernard P Roques, J L Darlix, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg Human immunodeficiency virus Type 1 n...
1996 J M Cherrington, M D Fuller, A S Mulato, S J Allen, S C Kunder, M A Ussery, Z Lesnikowski, Raymond F Schinazi, J P Sommadossi, M S Chen Comparative kinetic analyses of inter...
1996 D Bellarosa, G Antonelli, F Bambacioni, D Giannotti, G Viti, R Nannicini, A Giachetti, F Dianzani, Myriam Witvrouw, Rudi Pauwels, J Desmyter, Erik De Clercq New arylpyrido-diazepine and -thiodia...
1996 Dominique Arion, Ronald S Fletcher, G Borkow, María-José Camarasa, Jan Balzarini, G I Dmitrienko, Michael A. Parniak Differences in the inhibition of huma...
1996 H Jonckheere, K De Vreese, Zeger Debyser, J Vandekerckhove, Jan Balzarini, J Desmyter, Erik De Clercq, J Anné A two plasmid co-expression system in...
1996 S Ingate, Erik De Clercq, Jan Balzarini, María-José Camarasa Novel L-lyxo and 5'-deoxy-5'-modified...
1996 William A Beard, Dana T Minnick, C L Wade, Rajendra Prasad, R L Won, A Kumar, Thomas A Kunkel, Samuel H Wilson Role of the "helix clamp" in HIV-1 re...
1996 Mark A. Wainberg, L Lewis, H Salomon, Z Gu, A Keller, Nick Cammack, J Goldsmith, J Church, Bonnie Spira, S Wheeler, P Pizzo Resistance to (-)-2',3'-dideoxy-3'-th...
1996 Z Gu, Xincang Li, Yudong Quan, Michael A. Parniak, Mark A. Wainberg Studies of neutralizing monoclonal an...
1996 Mark A. Wainberg, William C Drosopoulos, H Salomon, M Hsu, G Borkow, M Parniak, Z Gu, Q Song, J Manne, S Islam, G Castriota, Vinayaka R Prasad Enhanced fidelity of 3TC-selected mut...
1996 Ronald S Fletcher, G Holleschak, Eva Nagy, Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak Single-step purification of recombina...
1996 E.J. Arts, J P Marois, Z Gu, Stuart F J Le Grice, Mark A. Wainberg Effects of 3'-deoxynucleoside 5'-trip...
1996 Jan Balzarini, O Wedgwood, J Kruining, H Pelemans, R Heijtink, Erik De Clercq, Christopher McGuigan Anti-HIV and anti-HBV activity and re...
1996 Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak The K65R mutation confers increased D... RT,Cloned or native,Full length or truncated,Extension from RNA primer,All properties
1996 L Hong, A Treharne, J A Hartsuck, S Foundling, J Tang Crystal structures of complexes of a ...
1996 M Evers, C Poujade, F Soler, Y Ribeill, C James, Y Lelièvre, J C Gueguen, D Reisdorf, I Morize, Rudi Pauwels, Erik De Clercq, Y Hénin, Anne Bousseau, J F Mayaux, J B Le Pecq, N Dereu Betulinic acid derivatives: a new cla...
1996 F Soler, C Poujade, M Evers, J C Carry, Y Hénin, Anne Bousseau, T Huet, Rudi Pauwels, Erik De Clercq, J F Mayaux, J B Le Pecq, N Dereu Betulinic acid derivatives: a new cla...
1996 L M Mansky Forward mutation rate of human immuno...
1996 Jan Balzarini, H Pelemans, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson Marked inhibitory activity of non-nuc...
1996 J E Wilson, A Aulabaugh, B Caligan, S McPherson, J K Wakefield, S Jablonski, C D Morrow, J E Reardon, Phillip A Furman Human immunodeficiency virus type-1 r...
1996 Baek Kim, T R Hathaway, Lawrence A Loeb Human immunodeficiency virus reverse ...
1996 J Ji, N J Clegg, K R Peterson, A L Jackson, C D Laird, Lawrence A Loeb In vitro expansion of GGC:GCC repeats...
1996 CF Perno, Emanuela Balestra, Stefano Aquaro, S Panti, A Cenci, G Lazzarino, B Tavazzi, D Di Pierro, Jan Balzarini, R Calio Potent inhibition of human immunodefi...
1996 J A Esté, K De Vreese, Myriam Witvrouw, J C Schmit, A-M Vandamme, J Anné, J Desmyter, G W Henson, G Bridger, Erik De Clercq Antiviral activity of the bicyclam de...
1996 Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Stephen H Hughes, Edward Arnold Structure of unliganded HIV-1 reverse...
1996 D J Hooker, G Tachedjian, A E Solomon, A D Gurusinghe, S Land, C Birch, J L Anderson, B M Roy, Edward Arnold, N J Deacon An in vivo mutation from leucine to t...
1996 V N Pandey, Neerja Kaushik, N Rege, Stefan G Sarafianos, P N Yadav, Mukund J Modak Role of methionine 184 of human immun...
1996 N K Back, Monique Nijhuis, W Keulen, Charles A B Boucher, B O Oude Essink, A B van Kuilenburg, A H van Gennip, Ben Berkhout Reduced replication of 3TC-resistant ...
1996 R A Olmsted, D E Slade, L A Kopta, S M Poppe, T J Poel, S W Newport, K B Rank, C Biles, R A Morge, T J Dueweke, Y Yagi, D L Romero, R C Thomas, S K Sharma, W G Tarpley (Alkylamino) piperidine bis(heteroary...
1996 Edward Arnold, Kalyan Das, Jianping Ding, P N Yadav, Y Hsiou, Paul L Boyer, Stephen H Hughes Targeting HIV reverse transcriptase f...
1996 A Foli, K M Sogocio, B Anderson, M Kavlick, M W Saville, Mark A. Wainberg, Z Gu, J M Cherrington, Hiroyuki Mitsuya, R Yarchoan In vitro selection and molecular char...
1996 G Yang, Q Song, M Charles, William C Drosopoulos, Edward Arnold, Vinayaka R Prasad Use of chimeric human immunodeficienc...
1996 H D Sun, S X Qiu, L Z Lin, Z Y Wang, Z W Lin, T Pengsuparp, J M Pezzuto, H H Fong, G A Cordell, N R Farnsworth Nigranoic acid, a triterpenoid from S...
1996 Andrew L Hopkins, Jingshan Ren, R M Esnouf, B E Willcox, E Yvonne Jones, C Ross, T Miyasaka, R T Walker, Hiromichi Tanaka, David K Stammers, David I Stuart Complexes of HIV-1 reverse transcript...
1996 P Richard Harrigan, I Kinghorn, Stuart Bloor, S D Kemp, I Nájera, A Kohli, Brendan A Larder Significance of amino acid variation ...
1996 A M Martín-Hernández, Esteban Domingo, L Menéndez-Arias Human immunodeficiency virus type 1 r...
1996 Yudong Quan, Z Gu, Xincang Li, Zhongjie Li, C D Morrow, Mark A. Wainberg Endogenous reverse transcription assa...
1996 A K Iversen, R W Shafer, K Wehrly, M A Winters, J I Mullins, B Chesebro, T C Merigan Multidrug-resistant human immunodefic...
1996 Olga I Lavrik, Rajendra Prasad, William A Beard, I V Safronov, M I Dobrikov, Deepak K Srivastava, G V Shishkin, T G Wood, Samuel H Wilson dNTP binding to HIV-1 reverse transcr...
1996 J M Cherrington, A S Mulato, M D Fuller, M S Chen Novel mutation (K70E) in human immuno...
1996 R A Spence, Karen S Anderson, Kenneth A Johnson HIV-1 reverse transcriptase resistanc...
1996 G Tachedjian, J Mellors, H Bazmi, C Birch, J Mills Zidovudine resistance is suppressed b...
1996 William C Drosopoulos, Vinayaka R Prasad Increased polymerase fidelity of E89G...
1996 Yangxin Huang, A Shalom, Zhongjie Li, Jiong Wang, J Mak, Mark A. Wainberg, Lawrence Kleiman Effects of modifying the tRNA(3Lys) a...
1996 Kalyan Das, Jianping Ding, Y Hsiou, Arthur D Clark, H Moereels, Luc Koymans, Koen Andries, Rudi Pauwels, Paul A J Janssen, Paul L Boyer, Patrick K Clark, Richard H Smith, Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Edward Arnold Crystal structures of 8-Cl and 9-Cl T...
1996 Stefan G Sarafianos, U Kortz, M T Pope, Mukund J Modak Mechanism of polyoxometalate-mediated...
1996 Charles A B Boucher, W Keulen, T van Bommel, Monique Nijhuis, D de Jong, M D de Jong, P Schipper, N K Back Human immunodeficiency virus type 1 d...
1996 Michael J Lutz, H A Held, M Hottiger, Ulrich Hübscher, Steven A Benner Differential discrimination of DNA po...
1996 Erik De Clercq Chemotherapy of human immunodeficienc...
1995 Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak Glutamine 151 participates in the sub...
1995 Jan Balzarini Novel concepts in the treatment of hu...
1995 D W Rodgers, S J Gamblin, B A Harris, S Ray, J S Culp, B Hellmig, D J Woolf, C Debouck, S C Harrison The structure of unliganded reverse t...
1995 Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak Site-directed mutagenesis of arginine...
1995 Y Törnevik, B Ullman, Jan Balzarini, B Wahren, Staffan Eriksson Cytotoxicity of 3'-azido-3'-deoxythym...
1995 M Sala, S Wain-Hobson, F Schaeffer Human immunodeficiency virus type 1 r...
1995 L M Mansky, H M Temin Lower in vivo mutation rate of human ...
1995 P N Yadav, J S Yadav, Mukund J Modak Nucleoside drug resistance in HIV-1 r...
1995 N M Gray, C L Marr, C R Penn, J M Cameron, R C Bethell The intracellular phosphorylation of ...
1995 R A Spence, W M Kati, Karen S Anderson, Kenneth A Johnson Mechanism of inhibition of HIV-1 reve...
1995 R R Vyas, A K Basu DNA polymerase action on an oligonucl...
1995 Baek Kim, Lawrence A Loeb Human immunodeficiency virus reverse ...
1995 Z Gu, Yudong Quan, Zhongjie Li, E.J. Arts, Mark A. Wainberg Effects of non-nucleoside inhibitors ...
1995 M I Anazodo, H Salomon, A D Friesen, Mark A. Wainberg, J A Wright Antiviral activity and protection of ...
1995 E.J. Arts, Zhongjie Li, Mark A. Wainberg Analysis of Primer Extension and the ...
1995 V McKiel, Z Gu, Mark A. Wainberg, J Hiscott Inhibition of human immunodeficiency ...
1995 Ronald S Fletcher, Dominique Arion, G Borkow, Mark A. Wainberg, G I Dmitrienko, Michael A. Parniak Synergistic inhibition of HIV-1 rever...
1995 Mark A. Wainberg, Z Gu Targeting HIV reverse transcriptase i...
1995 R J Germinario, T DeSantis, Mark A. Wainberg Insulin-like growth factor 1 and insu...
1995 Z Gu, E.J. Arts, Michael A. Parniak, Mark A. Wainberg Mutated K65R recombinant reverse tran...
1995 M I Anazodo, Mark A. Wainberg, A D Friesen, J A Wright Sequence-specific inhibition of gene ...
1995 Mark A. Wainberg, Z Gu, H Salomon, E.J. Arts, Lawrence Kleiman, Michael A. Parniak, N Morin [Molecular basis and clinical signifi...
1995 M Ghosh, K J Howard, Craig E Cameron, Stephen J Benkovic, Stephen H Hughes, Stuart F J Le Grice Truncating alpha-helix E' of p66 huma...
1995 T Shirasaka, M F Kavlick, Takayuki Ueno, W Y Gao, E Kojima, M L Alcaide, S Chokekijchai, B M Roy, Edward Arnold, R Yarchoan Emergence of human immunodeficiency v...
1995 Brendan A Larder, S D Kemp, P Richard Harrigan Potential mechanism for sustained ant...
1995 Rob Schuurman, Monique Nijhuis, R van Leeuwen, P Schipper, D de Jong, P Collis, Sven A Danner, J Mulder, C Loveday, C Christopherson Rapid changes in human immunodeficien...
1995 K Rittinger, G Divita, R S Goody Human immunodeficiency virus reverse ...
1995 Matthias Götte, S Fackler, T Hermann, E Perola, Luciano Cellai, H J Gross, Stuart F J Le Grice, H Heumann HIV-1 reverse transcriptase-associate...
1995 Ronald S Fletcher, K Syed, S Mithani, G I Dmitrienko, Michael A. Parniak Carboxanilide derivative non-nucleosi...
1995 M Jaju, William A Beard, Samuel H Wilson Human immunodeficiency virus type 1 r...
1995 Hongxing Zhang, Yang Zhang, T Spicer, D Henrard, B J Poiesz Nascent human immunodeficiency virus ...
1995 Silvio Spadari, Giovanni Maga, A Verri, A Bendiscioli, L Tondelli, M Capobianco, F Colonna, A Garbesi, Federico Focher Lack of stereospecificity of some cel...
1995 Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari Stereospecificity of human DNA polyme...
1995 Baek Kim, Lawrence A Loeb A screen in Escherichia coli for nucl...
1995 Edward Arnold, Jianping Ding, Stephen H Hughes, Z Hostomsky Structures of DNA and RNA polymerases...
1995 Katarzyna Bebenek, William A Beard, J R Casas-Finet, H R Kim, Thomas A Darden, Samuel H Wilson, Thomas A Kunkel Reduced frameshift fidelity and proce...
1995 B M Wöhrl, C Tantillo, Edward Arnold, Stuart F J Le Grice An expanded model of replicating huma...
1995 P H Patel, A Jacobo-Molina, Jianping Ding, C Tantillo, Art D Clark, R Raag, R G Nanni, Stephen H Hughes, Edward Arnold Insights into DNA polymerization mech...
1995 Jörg-Peter Kleim, R Bender, R Kirsch, C Meichsner, A Paessens, M Rösner, H Rübsamen-Waigmann, R Kaiser, M Wichers, K E Schneweis Preclinical evaluation of HBY 097, a ...
1995 Marilyn B Kroeger Smith, C A Rouzer, L A Taneyhill, N A Smith, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, H Moereels, Luc Koymans, Edward Arnold Molecular modeling studies of HIV-1 r...
1995 Robert W Buckheit, V Fliakas-Boltz, S Yeagy-Bargo, O Weislow, D L Mayers, Paul L Boyer, Stephen H Hughes, B C Pan, S H Chu, J P Bader Resistance to 1-[(2-hydroxyethoxy)met...
1995 Haijiang Zhang, L Vrang, K Bäckbro, P Lind, Christer Sahlberg, Torsten Unge, Bo Oberg Inhibition of human immunodeficiency ...
1995 Robert W Buckheit, T L Kinjerski, V Fliakas-Boltz, J D Russell, T L Stup, L A Pallansch, W G Brouwer, D C Dao, W A Harrison, R J Schultz Structure-activity and cross-resistan...
1995 Jan Balzarini, María-Jesús Pérez-Pérez, S Vélazquez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson Suppression of the breakthrough of hu...
1995 M Hottiger, K Gramatikoff, O Georgiev, C Chaponnier, W Schaffner, Ulrich Hübscher The large subunit of HIV-1 reverse tr...
1995 J Horlacher, M Hottiger, Vladimir N Podust, Ulrich Hübscher, Steven A Benner Recognition by viral and cellular DNA...
1995 S D Young, S F Britcher, L O Tran, L S Payne, W C Lumma, T A Lyle, J R Huff, P S Anderson, David B Olsen, Steven S Carroll L-743, 726 (DMP-266): a novel, highly...
1995 Katarzyna Bebenek, Thomas A Kunkel Analyzing fidelity of DNA polymerases. Frameshift Error Rate,Overall Error Rate,All properties
1995 G Tachedjian, D J Hooker, A D Gurusinghe, H Bazmi, N J Deacon, J Mellors, C Birch, J Mills Characterisation of foscarnet-resista...
1995 Takayuki Ueno, T Shirasaka, Hiroyuki Mitsuya Enzymatic characterization of human i...
1995 John W Mellors, Holly Z Bazmi, Raymond F Schinazi, B M Roy, Y Hsiou, Edward Arnold, J Weir, D L Mayers Novel mutations in reverse transcript...
1995 Jingshan Ren, R Esnouf, E Garman, D Somers, C Ross, I Kirby, J Keeling, G Darby, Y Jones, David I Stuart High resolution structures of HIV-1 R...
1995 Jianping Ding, Kalyan Das, H Moereels, Luc Koymans, Koen Andries, Paul A J Janssen, Stephen H Hughes, Edward Arnold Structure of HIV-1 RT/TIBO R 86183 co...
1995 R Esnouf, Jingshan Ren, C Ross, Y Jones, D Stammers, David I Stuart Mechanism of inhibition of HIV-1 reve...
1995 Jingshan Ren, R Esnouf, A Hopkins, C Ross, Y Jones, D Stammers, David I Stuart The structure of HIV-1 reverse transc...
1995 Jianping Ding, Kalyan Das, C Tantillo, Weiming Zhang, Arthur D Clark, S Jessen, Xiaoqing Lu, Y Hsiou, A Jacobo-Molina, Koen Andries Structure of HIV-1 reverse transcript...
1995 Erik De Clercq, Jan Balzarini Knocking out human immunodeficiency v...
1995 Jan Balzarini, M Weeger, María-José Camarasa, Erik De Clercq, K Uberla Sensitivity/resistance profile of a s...
1995 Jan Balzarini, W G Brouwer, E E Felauer, Erik De Clercq, Anna Karlsson Activity of various thiocarboxanilide...
1995 Sonsoles Velázquez, R Alvarez, Ana San-Félix, M L Jimeno, Erik De Clercq, Jan Balzarini, María-José Camarasa Synthesis and anti-HIV activity of [A...
1995 Jan Balzarini, Masanori Baba, Erik De Clercq Differential activities of 1-[(2-hydr...
1994 Jan Balzarini, Anna Karlsson, C Meichsner, A Paessens, G Riess, Erik De Clercq, Jörg-Peter Kleim Resistance pattern of human immunodef...
1994 Torsten Unge, S Knight, R Bhikhabhai, S Lövgren, Z Dauter, K Wilson, B Strandberg 2.2 A resolution structure of the ami...
1994 Jianping Ding, A Jacobo-Molina, C Tantillo, Xiaoqing Lu, R G Nanni, Edward Arnold Buried surface analysis of HIV-1 reve...
1994 S F Lacey, Brendan A Larder Novel mutation (V75T) in human immuno...
1994 T Hermann, T Meier, Matthias Götte, H Heumann The 'helix clamp' in HIV-1 reverse tr...
1994 Rudi Pauwels, Koen Andries, Zeger Debyser, Michael J Kukla, Dominique Schols, H J Breslin, R Woestenborghs, J Desmyter, M A Janssen, Erik De Clercq New tetrahydroimidazo[4,5,1-jk][1,4]-...
1994 P S Jacques, B M Wöhrl, M Ottmann, J L Darlix, Stuart F J Le Grice Mutating the "primer grip" of p66 HIV...
1994 Erik De Clercq How to overcome resistance of HIV-1 t...
1994 Erik De Clercq New developments in the chemotherapy ...
1994 Masanori Baba, S Shigeta, S Yuasa, H Takashima, K Sekiya, M Ubasawa, Hiromichi Tanaka, T Miyasaka, R T Walker, Erik De Clercq Preclinical evaluation of MKC-442, a ...
1994 Erik De Clercq HIV resistance to reverse transcripta...
1994 J Mak, M Jiang, Mark A. Wainberg, M L Hammarskjöld, D Rekosh, Lawrence Kleiman Role of Pr160gag-pol in mediating the...
1994 Z Gu, Q Gao, H Fang, Michael A. Parniak, Bluma G Brenner, Mark A. Wainberg Identification of novel mutations tha...
1994 S Zinnen, J C Hsieh, P Modrich Misincorporation and mispaired primer...
1994 E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg Mature reverse transcriptase (p66/p51...
1994 Paul L Boyer, C Tantillo, A Jacobo-Molina, R G Nanni, Jianping Ding, Edward Arnold, Stephen H Hughes Sensitivity of wild-type human immuno...
1994 L Mercure, B J Brenner, D Phaneuf, C Tsoukas, Mark A. Wainberg Effect of 3'-azido-3'-deoxythymidine ...
1994 E.J. Arts, Xincang Li, Z Gu, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg Comparison of deoxyoligonucleotide an...
1994 S J Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, A J Chirino, J M Friedman, P A Rice, Thomas A Steitz Structure of the binding site for non...
1994 V W Byrnes, E A Emini, W A Schleif, J H Condra, C L Schneider, W J Long, J A Wolfgang, D J Graham, L Gotlib, A J Schlabach Susceptibilities of human immunodefic...
1994 M Smith, H Salomon, Mark A. Wainberg Development and significance of nucle...
1994 E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg DNA found in human immunodeficiency v...
1994 Z Gu, Ronald S Fletcher, E.J. Arts, Mark A. Wainberg, Michael A. Parniak The K65R mutant reverse transcriptase...
1994 P N Yadav, J S Yadav, Edward Arnold, Mukund J Modak A computer-assisted analysis of conse...
1994 M R Sawaya, H Pelletier, A Kumar, Samuel H Wilson, J Kraut Crystal structure of rat DNA polymera...
1994 Jan Balzarini, Jörg-Peter Kleim, G Riess, María-José Camarasa, Erik De Clercq, Anna Karlsson Sensitivity of (138 Glu-->Lys) mutate...
1994 J Ji, Lawrence A Loeb Fidelity of HIV-1 reverse transcripta...
1994 H Jonckheere, J M Taymans, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, J Desmyter, Erik De Clercq, J Anné Resistance of HIV-1 reverse transcrip...
1994 M H Nguyen, Raymond F Schinazi, C Shi, N M Goudgaon, P M McKenna, John W Mellors Resistance of human immunodeficiency ...
1994 A-M Vandamme, Zeger Debyser, Rudi Pauwels, K De Vreese, P Goubau, M Youle, B Gazzard, P A Stoffels, G F Cauwenbergh, J Anne Characterization of HIV-1 strains iso...
1994 S Loya, M Bakhanashvili, R Tal, Stephen H Hughes, Paul L Boyer, A Hizi Enzymatic properties of two mutants o...
1994 Jan Balzarini, Anna Karlsson, V V Sardana, E A Emini, María-José Camarasa, Erik De Clercq Human immunodeficiency virus 1 (HIV-1...
1994 G Gosselin, Raymond F Schinazi, J P Sommadossi, C Mathé, M C Bergogne, A M Aubertin, A Kirn, J L Imbach Anti-human immunodeficiency virus act...
1994 Myron F Goodman, H Cai, Linda B Bloom, R Eritja Nucleotide insertion and primer exten...
1994 Paul L Boyer, Andrea L Ferris, Patrick K Clark, J Whitmer, P Frank, C Tantillo, Edward Arnold, Stephen H Hughes Mutational analysis of the fingers an...
1994 J Ji, Jean-Sébastien Hoffmann, L Loeb Mutagenicity and pausing of HIV rever...
1994 I Kang, Jing-Houng Wang Design of structure-based reverse tra...
1994 C Tantillo, Jianping Ding, A Jacobo-Molina, R G Nanni, Paul L Boyer, Stephen H Hughes, Rudi Pauwels, Koen Andries, Paul A J Janssen, Edward Arnold Locations of anti-AIDS drug binding s...
1994 M Hottiger, Vladimir N Podust, R L Thimmig, C McHenry, Ulrich Hübscher Strand displacement activity of the h...
1994 William A Beard, Samuel H Wilson Site-directed mutagenesis of HIV reve...
1994 Douglas D Richman, D Havlir, J Corbeil, D Looney, C Ignacio, S A Spector, J Sullivan, S Cheeseman, K Barringer, D Pauletti Nevirapine resistance mutations of hu...
1994 H Pelletier, M R Sawaya, A Kumar, Samuel H Wilson, J Kraut Structures of ternary complexes of ra...
1994 M D Delahunty, Samuel H Wilson, R L Karpel Studies on primer binding of HIV-1 re...
1994 M A Fisher, P N Yadav, J Yadav, D Kristol, Edward Arnold, Mukund J Modak Identification of a pharmacophore for...
1994 T Rubinek, S Loya, M Shaharabany, Stephen H Hughes, Patrick K Clark, A Hizi The catalytic properties of the rever...
1994 S V Doronin, M I Dobrikov, M Buckle, P Roux, H Buc, Olga I Lavrik Affinity modification of human immuno...
1994 J Jäger, S J Smerdon, Jianhong Wang, D C Boisvert, Thomas A Steitz Comparison of three different crystal...
1994 A Okruszek, M Olesiak, Jan Balzarini The synthesis of nucleoside 5'-O-(1,1...
1994 Paul L Boyer, Jianping Ding, Edward Arnold, Stephen H Hughes Subunit specificity of mutations that...
1993 G T Tan, A Wickramasinghe, S Verma, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan Sulfonic acid polymers are potent inh...
1993 A Hizi, R Tal, M Shaharabany, M J Currens, M R Boyd, Stephen H Hughes, James B McMahon Specific inhibition of the reverse tr...
1993 R L Thimmig, Charles S McHenry Human immunodeficiency virus reverse ...
1993 H Cai, Linda B Bloom, R Eritja, Myron F Goodman Kinetics of deoxyribonucleotide inser...
1993 S St Luce, E Arts, R Geleziunas, S Bour, Mark A. Wainberg Infection of human monocyte-derived m...
1993 Xincang Li, E Amandoron, Mark A. Wainberg, Michael A. Parniak Generation and characterization of mu...
1993 Mark A. Wainberg, H Salomon, Bonnie Spira, L Mercure, J Wainberg, K Nagai, Z Bentwich, J Montaner HIV resistance to anti-viral drugs.
1993 Mark A. Wainberg, Z Gu, Q Gao, E Arts, R Geleziunas, S Bour, R Beaulieu, C Tsoukas, J Singer, J Montaner Clinical correlates and molecular bas...
1993 R Goel, William A Beard, A Kumar, J R Casas-Finet, M P Strub, S J Stahl, M S Lewis, Katarzyna Bebenek, S P Becerra, Thomas A Kunkel Structure/function studies of HIV-1(1...
1993 J Abbotts, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson Mechanism of HIV-1 reverse transcript...
1993 Katarzyna Bebenek, J Abbotts, Samuel H Wilson, Thomas A Kunkel Error-prone polymerization by HIV-1 r...
1993 S P Becerra, A Kumar, Samuel H Wilson Expression of polypeptides of human i...
1993 A Kumar, H R Kim, Robert W Sobol, S P Becerra, B J Lee, D L Hatfield, R J Suhadolnik, Samuel H Wilson Mapping of nucleic acid binding in pr...
1993 William A Beard, Samuel H Wilson Kinetic analysis of template.primer i...
1993 Robert W Sobol, W L Fisher, N L Reichenbach, A Kumar, William A Beard, Samuel H Wilson, R Charubala, W Pfleiderer, R J Suhadolnik HIV-1 reverse transcriptase: inhibiti...
1993 C T Wang, Yongqing Zhang, J McDermott, E Barklis Conditional infectivity of a human im...
1993 Svetlana N Khodyreva, Vladimir N Podust, D S Sergeev, E M Ivanova, E I Frolova, A A Koshkin, T S Godovikova, V F Zarytova, Miria Ricchetti, Olga I Lavrik Comparison of interactions of 5'-deri...
1993 S Kawa, A Kumar, J S Smith, S P Becerra, William A Beard, Samuel H Wilson, E B Thompson Expression and purification of the HI...
1993 T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley A mutation in reverse transcriptase o...
1993 Jörg-Peter Kleim, R Bender, U M Billhardt, C Meichsner, G Riess, M Rösner, I Winkler, A Paessens Activity of a novel quinoxaline deriv...
1993 G Maass, U Immendoerfer, B Koenig, U Leser, B Mueller, R Goody, E Pfaff Viral resistance to the thiazolo-iso-...
1993 Jan Balzarini, Anna Karlsson, A-M Vandamme, María-Jesús Pérez-Pérez, Haijiang Zhang, L Vrang, Bo Oberg, K Bäckbro, Torsten Unge, Ana San-Félix Human immunodeficiency virus type 1 (...
1993 Jan Balzarini, Sonsoles Velazquez, A San-Felix, Anna Karlsson, M J Perez-Perez, María-José Camarasa, Erik De Clercq Human immunodeficiency virus type 1-s...
1993 Jan Balzarini, Anna Karlsson, Erik De Clercq Human immunodeficiency virus type 1 d...
1993 M S Saag, E A Emini, O L Laskin, J Douglas, W I Lapidus, W A Schleif, R J Whitley, C Hildebrand, V W Byrnes, John C Kappes A short-term clinical evaluation of L...
1993 Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, L Vrang, J Walbers, Haijiang Zhang, Bo Oberg, A-M Vandamme, María-José Camarasa, Erik De Clercq HIV-1-specific reverse transcriptase ...
1993 John W Mellors, G J Im, Enzo Tramontano, S R Winkler, D J Medina, Ginger E Dutschman, Holly Z Bazmi, G Piras, C J Gonzalez, Yung-Chi Cheng A single conservative amino acid subs...
1993 Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, W G Tarpley, Erik De Clercq Treatment of human immunodeficiency v...
1993 Kristin A Eckert, Thomas A Kunkel Fidelity of DNA synthesis catalyzed b... Cloned or native,Full length or truncated,Specific Activity,3-5' exo,Nucleotide Substitution Rate,All properties
1993 M Tisdale, S D Kemp, N R Parry, Brendan A Larder Rapid in vitro selection of human imm...
1993 J L Martin, J E Wilson, R L Haynes, Phillip A Furman Mechanism of resistance of human immu...
1993 Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg The same mutation that encodes low-le...
1993 Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, Erik De Clercq Knocking-out concentrations of HIV-1-...
1993 J C Hsieh, S Zinnen, P Modrich Kinetic mechanism of the DNA-dependen...
1993 A Jacobo-Molina, Jianping Ding, R G Nanni, Arthur D Clark, Xiaoqing Lu, C Tantillo, R L Williams, G Kamer, Andrea L Ferris, Patrick K Clark Crystal structure of human immunodefi...
1993 W Y Gao, A Cara, R C Gallo, F Lori Low levels of deoxynucleotides in per...
1993 Johan Neyts, F Stals, C Bruggeman, Erik De Clercq Activity of the anti-HIV agent 9-(2-p...
1993 Erik De Clercq HIV-1-specific RT inhibitors: highly ...
1993 Zeger Debyser, K De Vreese, P P Knops-Gerrits, V Baekelandt, R Bhikhabhai, B Strandberg, Rudi Pauwels, J Anné, J Desmyter, Erik De Clercq Kinetics of different human immunodef...
1993 Erik De Clercq Antiviral agents: characteristic acti...
1993 Thomas A Steitz, S Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, J M Friedman, Lorena S Beese, P A Rice Two DNA polymerases: HIV reverse tran...
1993 D Chattopadhyay, B C Finzel, S H Munson, D B Evans, S K Sharma, N A Strakalaitus, D P Brunner, F M Eckenrode, Z Dauter, C Betzel, H M Einspahr Crystallographic analyses of an activ...
1993 Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors Characterization of human immunodefic...
1993 M S Chen, R T Suttmann, E Papp, P D Cannon, M J McRoberts, C Bach, William C Copeland, Teresa S-F Wang Selective action of 4'-azidothymidine...
1993 R Sousa, Y J Chung, J P Rose, B C Wang Crystal structure of bacteriophage T7...
1993 Myron F Goodman, S Creighton, Linda B Bloom, John Petruska Biochemical basis of DNA replication ...
1993 Paul L Boyer, M J Currens, James B McMahon, M R Boyd, Stephen H Hughes Analysis of nonnucleoside drug-resist...
1992 Paul L Boyer, Andrea L Ferris, Stephen H Hughes Mutational analysis of the fingers do...
1992 M Jiang, J Mak, Mark A. Wainberg, Michael A. Parniak, E Cohen, Lawrence Kleiman Variable tRNA content in HIV-1IIIB.
1992 J C Boyer, Katarzyna Bebenek, Thomas A Kunkel Unequal human immunodeficiency virus ...
1992 F Boulerice, R Geleziunas, S Bour, H L Li, M D'Addario, A Roulston, J Hiscott, Mark A. Wainberg Differential susceptibilities of U-93...
1992 Mark A. Wainberg, R G Margolese Strategies in the treatment of AIDS a...
1992 A Hosmalin, S Kumar, D Barnd, R Houghten, G E Smith, Stephen H Hughes, J A Berzofsky Immunization with soluble protein-pul...
1992 S Loya, R Tal, Stephen H Hughes, A Hizi The effects of cysteine mutations on ...
1992 William C Copeland, M S Chen, Teresa S-F Wang Human DNA polymerases alpha and beta ...
1992 I I Fedorov, E M Kazmina, N A Novicov, Galina V Gurskaya, A V Bochkarev, M V Jasko, L S Victorova, M K Kukhanova, Jan Balzarini, Erik De Clercq 3'-C-branched 2'-deoxy-5-methyluridin...
1992 N Yamamoto, Dominique Schols, Erik De Clercq, Zeger Debyser, Rudi Pauwels, Jan Balzarini, H Nakashima, Masanori Baba, M Hosoya, Robert Snoeck Mechanism of anti-human immunodeficie...
1992 G T Tan, J F Miller, A D Kinghorn, Stephen H Hughes, J M Pezzuto HIV-1 and HIV-2 reverse transcriptase...
1992 Zeger Debyser, K De Vreese, Rudi Pauwels, N Yamamoto, J Anné, Erik De Clercq, J Desmyter Differential inhibitory effects of TI...
1992 Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, Masanori Baba, J Desmyter, Erik De Clercq Kinetics of inhibition of endogenous ...
1992 K De Vreese, Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, J Desmyter, Erik De Clercq, J Anné Resistance of human immunodeficiency ...
1992 Erik De Clercq HIV inhibitors targeted at the revers...
1992 Erik De Clercq New perspectives for the chemotherapy...
1992 Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Y Engelborghs, Paul A J Janssen, Erik De Clercq Allosteric inhibition of human immuno...
1992 Zeger Debyser, Rudi Pauwels, Koen Andries, Erik De Clercq Specific HIV-1 reverse transcriptase ...
1992 J P Ji, Lawrence A Loeb Fidelity of HIV-1 reverse transcripta...
1992 M M Huang, Norman Arnheim, Myron F Goodman Extension of base mispairs by Taq DNA...
1992 Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg Novel mutation in the human immunodef...
1992 Z Hostomsky, Z Hostomska, T B Fu, J Taylor Reverse transcriptase of human immuno...
1992 P Kellam, Charles A B Boucher, Brendan A Larder Fifth mutation in human immunodeficie...
1992 S F Lacey, J E Reardon, E S Furfine, Thomas A Kunkel, Katarzyna Bebenek, Kristin A Eckert, S D Kemp, Brendan A Larder Biochemical studies on the reverse tr...
1992 Brendan A Larder 3'-Azido-3'-deoxythymidine resistance...
1992 Edward Arnold, A Jacobo-Molina, R G Nanni, R L Williams, Xiaoqing Lu, Jianping Ding, Art D Clark, A Zhang, Andrea L Ferris, Patrick K Clark Structure of HIV-1 reverse transcript...
1992 L A Kohlstaedt, Thomas A Steitz Reverse transcriptase of human immuno...
1992 Tsuyoshi Yamaguchi, Shunji Izuta, Motoshi Suzuki, Shonen Yoshida, Akio Matsukage, Mineo Saneyoshi Inhibitory effects of 2'-deoxy-5-styr...
1992 J J DeStefano, R G Buiser, L M Mallaber, P J Fay, Robert A Bambara Parameters that influence processive ... RT,Full length or truncated,Specific Activity,Processivity,Molecular Weight,RNase H,All properties
1992 A Basu, K K Ahluwalia, S Basu, Mukund J Modak Identification of the primer binding ...
1992 J A Coates, Nick Cammack, H J Jenkinson, I M Mutton, B A Pearson, R Storer, J M Cameron, C R Penn The separated enantiomers of 2'-deoxy...
1992 J A Coates, Nick Cammack, H J Jenkinson, A J Jowett, M I Jowett, B A Pearson, C R Penn, P L Rouse, K C Viner, J M Cameron (-)-2'-deoxy-3'-thiacytidine is a pot...
1992 D L Mayers, F E McCutchan, E E Sanders-Buell, L I Merritt, S Dilworth, A K Fowler, C A Marks, N M Ruiz, Douglas D Richman, C R Roberts Characterization of HIV isolates aris...
1992 John W Mellors, Ginger E Dutschman, G J Im, Enzo Tramontano, S R Winkler, Yung-Chi Cheng In vitro selection and molecular char...
1992 R L Mitina, S V Doronin, M I Dobrikov, D R Tabatadze, A S Levina, Olga I Lavrik Human immunodeficiency virus type 1 r...
1992 W M Kati, Kenneth A Johnson, L F Jerva, Karen S Anderson Mechanism and fidelity of HIV reverse...
1992 G T Tan, A Wickramasinghe, S Verma, R Singh, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan Potential anti-AIDS naphthalenesulfon...
1992 Hong Yu, Myron F Goodman Comparison of HIV-1 and avian myelobl...
1992 V V Sardana, E A Emini, L Gotlib, D J Graham, D W Lineberger, W J Long, A J Schlabach, J A Wolfgang, J H Condra Functional analysis of HIV-1 reverse ...
1992 Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velazquez, María-José Camarasa, Erik De Clercq [2',5'-Bis-O-(tert-butyldimethylsilyl...
1992 J E Reardon Human immunodeficiency virus reverse ...
1992 M Bakhanashvili, A Hizi Fidelity of the reverse transcriptase... RT,3-5' exo,All properties
1992 J A Peliska, Stephen J Benkovic Mechanism of DNA strand transfer reac...
1992 M B Vasudevachari, C Battista, H C Lane, M C Psallidopoulos, B Zhao, J Cook, J R Palmer, D L Romero, W G Tarpley, N P Salzman Prevention of the spread of HIV-1 inf...
1992 A Basu, S Basu, Mukund J Modak Structure-activity analyses of HIV-1 ...
1992 Q Gao, Z X Gu, Michael A. Parniak, X G Li, Mark A. Wainberg In vitro selection of variants of hum...
1992 Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Dominique Schols, CF Perno, A-M Vandamme, María-José Camarasa, Erik De Clercq 2',5'-Bis-O-(tert-butyldimethylsilyl)...
1992 Shunji Izuta, N Shimada, Masatoshi Kitagawa, Motoshi Suzuki, K Kojima, Shonen Yoshida Inhibitory effects of triphosphate de...
1992 L A Kohlstaedt, Jianhong Wang, J M Friedman, P A Rice, Thomas A Steitz Crystal structure at 3.5 A resolution...
1992 J Abbotts, Samuel H Wilson Inhibitors of HIV-1 reverse transcrip...
1992 Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, I C Bathurst, P J Barr, Erik De Clercq Kinetics of inhibition of human immun...
1992 Alberto Bergamini, CF Perno, Jan Balzarini, M Capozzi, Luciana Marinelli, G Milanese, C D Pesce, R Calió, G Rocchi Selective inhibition of HIV replicati...
1992 L Ding, Jan Balzarini, Dominique Schols, B Meunier, Erik De Clercq Anti-human immunodeficiency virus eff...
1992 V Gopalakrishnan, J A Peliska, Stephen J Benkovic Human immunodeficiency virus type 1 r... RT,Terminal Transferase,RNase H,All properties
1992 C S Crumpacker Mechanism of action of foscarnet agai...
1991 D Richman, C K Shih, I Lowy, J Rose, P Prodanovich, S Goff, J Griffin Human immunodeficiency virus type 1 m...
1991 Jan Balzarini, Antonin Holy, J Jindrich, H Dvorakova, Z Hao, Robert Snoeck, Piet Herdewijn, D G Johns, Erik De Clercq 9-[(2RS)-3-fluoro-2-phosphonylmethoxy...
1991 P Hafkemeyer, K Neftel, R Hobi, A Pfaltz, H Lutz, K Lüthi, Federico Focher, Silvio Spadari, Ulrich Hübscher HP 0.35, a cephalosporin degradation ... RT,RNase H,All properties
1991 R S Goody, B Müller, Tobias Restle Factors contributing to the inhibitio...
1991 Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Michael Kukla, Paul A J Janssen, Erik De Clercq An antiviral target on reverse transc...
1991 E S Furfine, J E Reardon Reverse transcriptase.RNase H from th... RT,All properties
1991 Brendan A Larder, K E Coates, S D Kemp Zidovudine-resistant human immunodefi...
1991 E B Kopp, J J Miglietta, A G Shrutkowski, C K Shih, P M Grob, M T Skoog Steady state kinetics and inhibition ... KM,kcat,All properties
1991 M H St Clair, J L Martin, G Tudor-Williams, M C Bach, C L Vavro, D M King, P Kellam, S D Kemp, Brendan A Larder Resistance to ddI and sensitivity to ...
1991 A DeVico, R C Montelaro, R C Gallo, M G Sarngadharan Purification and partial characteriza... RT,Full length or truncated,3-5' exo,Nucleotide Substitution Rate,RNase H,All properties
1991 J H Nunberg, W A Schleif, E J Boots, J A O'Brien, J C Quintero, J M Hoffman, E A Emini, M E Goldman Viral resistance to human immunodefic...
1991 Olga I Lavrik Oligonucleotides and their derivative...
1991 S P Becerra, A Kumar, M S Lewis, S G Widen, J Abbotts, E M Karawya, Stephen H Hughes, J Shiloach, Samuel H Wilson, M S Lewis Protein-protein interactions of HIV-1...
1991 Robert W Sobol, R J Suhadolnik, A Kumar, B J Lee, D L Hatfield, Samuel H Wilson Localization of a polynucleotide bind...
1991 J G Baillon, N T Nashed, A Kumar, Samuel H Wilson, Donald M Jerina A leucine zipper-like motif may media...
1991 J Abbotts, M Jaju, Samuel H Wilson Thermodynamics of A:G mismatch poly(d...
1991 A Hizi, R Tal, Stephen H Hughes Mutational analysis of the DNA polyme...
1991 A S De Groot, M Clerici, A Hosmalin, Stephen H Hughes, D Barnd, C W Hendrix, R Houghten, G M Shearer, J A Berzofsky Human immunodeficiency virus reverse ...
1991 Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, R T Walker, S Mori Highly potent and selective inhibitio...
1991 Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, H Nakashima, S Mori Potent and selective inhibition of hu...
1991 Erik De Clercq Chemotherapy of the acquired immune d...
1991 Mark Cushman, S Kanamathareddy, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen Synthesis and anti-HIV activities of ...
1991 Mark Cushman, P L Wang, S H Chang, C Wild, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen Preparation and anti-HIV activities o...
1991 G T Tan, A D Kinghorn, Stephen H Hughes, J M Pezzuto Psychotrine and its O-methyl ether ar...
1991 P R Johnson, T E Hamm, S Goldstein, S Kitov, V M Hirsch The genetic fate of molecularly clone...
1991 Mark A. Wainberg, R Rooke, M Tremblay, Xincang Li, Michael A. Parniak, Q Gao, X J Yao, C Tsoukas, J Montaner, M Fanning, J Ruedy Clinical significance and characteriz...
1991 F Boulerice, X G Li, A Lvovich, Mark A. Wainberg Recovery of infectious human immunode...
1991 A Jacobo-Molina, Edward Arnold HIV reverse transcriptase structure-f...
1991 K B Frank, G J Noll, E V Connell, I S Sim Kinetic interaction of human immunode...
1991 Stuart F J Le Grice, T Naas, B Wohlgensinger, O Schatz Subunit-selective mutagenesis indicat...
1991 J E Reardon, E S Furfine, N Cheng Human immunodeficiency virus reverse ...
1991 M Tisdale, T Schulze, Brendan A Larder, K Moelling Mutations within the RNase H domain o...
1990 A M Barber, A Hizi, J V Maizel, Stephen H Hughes HIV-1 reverse transcriptase: structur...
1990 M Ricchetti, H Buc Reverse transcriptases and genomic va...
1990 A Hizi, Stephen H Hughes, M Shaharabany Mutational analysis of the ribonuclea...
1990 Stuart F J Le Grice, F Grüninger-Leitch Rapid purification of homodimer and h...
1990 M Tremblay, K Numazaki, X G Li, M Gornitsky, J Hiscott, Mark A. Wainberg Resistance to infection by HIV-1 of p...
1990 W E Müller, E Matthes, P Reuter, R Wenger, K Friese, Y Kuchino, H C Schröder Effect of nonviable preparations from...
1990 Mark A. Wainberg, Bonnie Spira, G Bleau, R Thomas Inactivation of human immunodeficienc...
1990 M Tremblay, K Numazaki, H Goldman, Mark A. Wainberg Infection of human thymic lymphocytes...
1990 A I Glukhov, S A Gordeev, S V Vinogradov, V I Kiselev, V M Kramarov, O I Kiselev, E S Severin Amplification of DNA sequences of Eps...
1990 Padmini S Kedar, J Abbotts, T Kovács, K Lesiak, P Torrence, Samuel H Wilson Mechanism of HIV reverse transcriptas...
1990 S P Becerra, G M Clore, A M Gronenborn, A R Karlström, S J Stahl, Samuel H Wilson, P T Wingfield Purification and characterization of ...
1990 Andrea L Ferris, A Hizi, S D Showalter, S Pichuantes, L Babe, C S Craik, Stephen H Hughes Immunologic and proteolytic analysis ...
1990 V J Merluzzi, K D Hargrave, M Labadia, K Grozinger, M Skoog, J C Wu, C K Shih, K Eckner, S Hattox, J Adams Inhibition of HIV-1 replication by a ...
1990 K J Williams, Lawrence A Loeb, M Fry Synthesis of DNA by human immunodefic...
1990 J E Reardon, W H Miller Human immunodeficiency virus reverse ... KM,kcat,All properties
1990 Brendan A Larder, B Chesebro, Douglas D Richman Susceptibilities of zidovudine-suscep...
1990 Z Hao, D A Cooney, D Farquhar, CF Perno, K Zhang, R Masood, Y Wilson, N R Hartman, Jan Balzarini, D G Johns Potent DNA chain termination activity...
1990 Erik De Clercq Selective virus inhibitors.
1990 R Rooke, M Tremblay, Mark A. Wainberg AZT (zidovudine) may act postintegrat...
1990 Erik De Clercq Targets and strategies for the antivi...
1990 F Boulerice, Mark A. Wainberg Inhibition by AZT of HIV-1 replicatio...
1989 Fred W Perrino, Bradley D Preston, L L Sandell, Lawrence A Loeb Extension of mismatched 3' termini of...
1989 Erik De Clercq Potential drugs for the treatment of ...
1989 M Ito, Masanori Baba, A Sato, K Hirabayashi, F Tanabe, S Shigeta, Erik De Clercq Tumor necrosis factor enhances replic...
1989 Brendan A Larder, S D Kemp Multiple mutations in HIV-1 reverse t...
1989 A Basu, R S Tirumalai, Mukund J Modak Substrate binding in human immunodefi...
1989 H E Huber, J M McCoy, J S Seehra, Charles C Richardson Human immunodeficiency virus 1 revers... Processivity,3-5' exo,5-3' exo,KM,Kd,RNase H,All properties
1989 C Majumdar, C A Stein, J S Cohen, S Broder, Samuel H Wilson Stepwise mechanism of HIV reverse tra...
1989 Masanori Baba, Hiromichi Tanaka, Erik De Clercq, Rudi Pauwels, Jan Balzarini, Dominique Schols, H Nakashima, CF Perno, R T Walker, T Miyasaka Highly specific inhibition of human i...
1989 M Tremblay, M Gornitsky, Mark A. Wainberg Active replication of human immunodef...
1989 B Müller, Tobias Restle, S Weiss, M Gautel, G Sczakiel, R S Goody Co-expression of the subunits of the ...
1989 Dominique Schols, Masanori Baba, Rudi Pauwels, Erik De Clercq Flow cytometric method to demonstrate...
1989 K Numazaki, X Q Bai, H Goldman, I Wong, Bonnie Spira, Mark A. Wainberg Infection of cultured human thymic ep...
1989 M Tremblay, Mark A. Wainberg Susceptibility of EBV-carrying B cell...
1989 A Hizi, A Barber, Stephen H Hughes Effects of small insertions on the RN...
1989 Masanori Baba, Dominique Schols, H Nakashima, Rudi Pauwels, G Parmentier, D K Meijer, Erik De Clercq Selective activity of several cholic ...
1988 Bradley D Preston, B J Poiesz, Lawrence A Loeb Fidelity of HIV-1 reverse transcriptase.
1988 E M Wondrak, J Löwer, R Kurth Inhibition of HIV-1 RNA-dependent DNA...
1988 A Hizi, C McGill, Stephen H Hughes Expression of soluble, enzymatically ...
1988 M Tremblay, L Fitz-Gibbon, Mark A. Wainberg Heterogeneity of HIV-1 replication an...
1988 Sujit Roy, L Fitz-Gibbon, L Poulin, Mark A. Wainberg Infection of human monocytes/macropha...
1988 J D Roberts, Katarzyna Bebenek, Thomas A Kunkel The accuracy of reverse transcriptase...
1988 Masanori Baba, Dominique Schols, Rudi Pauwels, Jan Balzarini, Erik De Clercq Fuchsin acid selectively inhibits hum...
1988 Masanori Baba, Rudi Pauwels, Jan Balzarini, J Arnout, J Desmyter, Erik De Clercq Mechanism of inhibitory effect of dex...
1988 Erik De Clercq Perspectives for the chemotherapy of ...
1987 Brendan A Larder, D J Purifoy, K L Powell, G Darby Site-specific mutagenesis of AIDS vir...
1987 M Ito, H Nakashima, Masanori Baba, Rudi Pauwels, Erik De Clercq, S Shigeta, N Yamamoto Inhibitory effect of glycyrrhizin on ...
1986 M S Johnson, M A McClure, D F Feng, J Gray, R F Doolittle Computer analysis of retroviral pol g...
1986 F di Marzo Veronese, T D Copeland, A L DeVico, R Rahman, S Oroszlan, R C Gallo, M G Sarngadharan Characterization of highly immunogeni...
1986 H A Blough, Rudi Pauwels, Erik De Clercq, J Cogniaux, S Sprecher-Goldberger, L Thiry Glycosylation inhibitors block the ex...
1986 M M Lightfoote, J E Coligan, T M Folks, A S Fauci, M A Martin, S Venkatesan Structural characterization of revers...
1985 A D Hoffman, B Banapour, J A Levy Characterization of the AIDS-associat...
DNA sequence:
Name 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
HIV RT V35I
HIV RT T39A
HIV RT M41LD67N/K70R/M184V/T215Y
HIV RT M41L
HIV RT M41LT215Y
HIV RT K43Q
HIV RT K43E
HIV RT E44D
HIV RT E44A
HIV RT I50V
HIV RT P52R
HIV RT N54D
HIV RT F61Y
HIV RT F61W
HIV RT F61A
HIV RT F61L
HIV RT A62T
HIV RT A62V
HIV RT K65R
HIV RT D67N
HIV RT D67A
HIV RT D67el
HIV RT D67G
HIV RT S68N
HIV RT T69D
HIV RT T69TRVMG
HIV RT T69G
HIV RT T69TSG
HIV RT K70E
HIV RT K70R
HIV RT R72A
HIV RT R72K
HIV RT L74V
HIV RT L74I
HIV RT V75M
HIV RT V75T
HIV RT V75I
HIV RT V75L
HIV RT R83K
HIV RT W88S
HIV RT W88G
HIV RT E89G
HIV RT E89K
HIV RT L92I
HIV RT A98G
HIV RT L100I
HIV RT K101I
HIV RT K101P
HIV RT K101Q
HIV RT K101E
HIV RT K103N, C280S
HIV RT K103T
HIV RT K103E
HIV RT K103Q
HIV RT K103R
HIV RT K103NY181C
HIV RT K103N
HIV RT V106I
HIV RT V106A
HIV RT V106M
HIV RT R172KV106M
HIV RT V108I
HIV RT R172KV108I
HIV RT G112S
HIV RT Y115F
HIV RT V118I
HIV RT P119S
HIV RT K122E
HIV RT I135L
HIV RT I135M
HIV RT I135T
HIV RT E138Q
HIV RT E138A
HIV RT E138G
HIV RT E138K
HIV RT E138R
HIV RT T139I
HIV RT G141E
HIV RT P143S
HIV RT Q151M
HIV RT S156A
HIV RT P157S
HIV RT Q161L
HIV RT V179D
HIV RT V179E
HIV RT V179F
HIV RT Y181I
HIV RT Y181C
HIV RT Y181V
HIV RT M184I
HIV RT M184T
HIV RT M184V
HIV RT Y188H
HIV RT Y188L
HIV RT Y188C
HIV RT Y188L, C280S
HIV RT V189I
HIV RT G190T
HIV RT G190V
HIV RT G190Q
HIV RT G190R
HIV RT G190A
HIV RT G190E
HIV RT G190S
HIV RT G190C
HIV RT E203K
HIV RT H208Y
HIV RT L210W
HIV RT L214F
HIV RT T215Y
HIV RT T215F
HIV RT D218E
HIV RT K219Q
HIV RT K219E
HIV RT P225H
HIV RT F227L
HIV RT F227C
HIV RT L234I
HIV RT P236L
HIV RT C280S,Q258C
HIV RT A272P
HIV RT K277R
HIV RT K281R
HIV RT L283I
HIV RT T286A
HIV RT E291D
HIV RT V292I
HIV RT I293V
HIV RT I293V
HIV RT E312Q
HIV RT Y318F
HIV RT G335C
HIV RT G335D
HIV RT N348I
HIV RT A360I
HIV RT A360V
HIV RT V365I
HIV RT A376S
HIV RT RNaseH omain
HIV RT N-term half

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