HIV RT
From
HIV
Welcome to the Polymerase Page
This page presents all the information in Polbase for HIV RT.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
HIV RT
is a family RT enzyme
from
HIV.
Selected Properties for HIV RT: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| No (4) | No (1) | 8.0e-06-4.7e-03 errors/bp (3) | 2.6e-05-3.2e-03 errors/bp (5) | 7.5e-05-8.0e-02 errors/bp (4) |
| Year | Authors | Title | Results by property |
|---|---|---|---|
| Erik De Clercq | Novel compounds in preclinical/early ... | ||
| Chen Liang, Mark A. Wainberg | The role of Tat in HIV-1 replication:... | ||
| G T Tan, J M Pezzuto, A D Kinghorn, Stephen H Hughes | Evaluation of natural products as inh... | ||
| Jorge L Martínez-Cajas, Nitika Pant-Pai, Marina B Klein, Mark A. Wainberg | Role of genetic diversity amongst HIV... | ||
| María-Cruz Bonache, Cristina Chamorro, Sonsoles Velázquez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Ana San-Félix | N-3 substituted TSAO derivatives as a... | ||
| N Gashnikova, O Plyasunova, Y Kiseleva, N Fedyuk, A Pokrovsky | In vitro study of resistance-associat... | ||
| Rudi Pauwels, M P de Bethune, Koen Andries, Paul Stoffels, P Janssen, Erik De Clercq | Discovery, development and characteri... | ||
| Paul J Lewi, Marc R De Jonge, Frits F D Daeyaert, Luc Koymans, Maarten H Vinkers, Jan Heeres, Paul A J Janssen, Edward Arnold, Kalyan Das, Art D Clark, Stephen H Hughes, Paul L Boyer, Marie-Pierre P De Béthune, Rudi Pauwels, Koen Andries, Michael Kukla, Donald W Ludovici, Bart De Corte, Robert W Kavash, Chih Y Ho, Paul J Lewis | On the detection of multiple-binding ... | ||
| Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari | Structural determinants of HIV-1 reve... | ||
| N Düzgünes, S Simões, V Slepushkin, E Pretzer, J J Rossi, Erik De Clercq, V P Antao, M L Collins, M C de Lima | Enhanced inhibition of HIV-1 replicat... | ||
| Erik De Clercq | New developments in anti-HIV chemothe... | ||
| Maria Letizia Barreca, Laura De Luca, Nunzio Iraci, Angela Rao, Stefania Ferro, Giovanni Maga, Alba Chimirri | Structure-based pharmacophore identif... | ||
| Sherine S L Chan, Janine H Santos, Joel N Meyer, Bhaskar S Mandavilli, Dennis L Cook, Consuelo L McCash, Grace E Kissling, Abraham Nyska, Julie F Foley, Bennett Van Houten, William C Copeland, Vernon E Walker, Kristine L Witt, Jack B Bishop | Mitochondrial toxicity in hearts of C... | ||
| Mark A. Wainberg, S Bour, R Geleziunas, Z Bentwich | [Antiviral strategies in the replicat... | ||
| Erik De Clercq | Perspectives of non-nucleoside revers... | ||
| P Hafkemeyer, K A Neftel, Ulrich Hübscher | HIV-reverse transcriptase and human D... | ||
| Erik De Clercq, Robert Snoeck | [Current acquisitions in antiviral dr... | ||
| Erik De Clercq | Perspectives for the chemotherapy of ... | ||
| 2013 | Mariela Bollini, Kathleen M Frey, José A Cisneros, Krasimir A Spasov, Kalyan Das, Joseph David Bauman, Edward Arnold, Karen S Anderson, William L Jorgensen | Extension into the entrance channel o... | |
| 2013 | Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Xinyong Liu | Novel piperidinylamino-diarylpyrimidi... | |
| 2013 | Venkata Ramana Sirivolu, Sanjeev Kumar V Verneka, Tatiana Ilina, Nataliya S Myshakina, Michael A. Parniak, Zhengqiang Wang | Clicking 3'-azidothymidine into novel... | |
| 2013 | Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd | Inhibition of HIV-1 Reverse Transcrip... | |
| 2013 | R S K Vijayan, Edward Arnold, Kalyan Das | Molecular dynamics study of HIV-1 RT-... | |
| 2013 | Karen A Kirby, Eleftherios Michailidis, Tracy L Fetterly, MA Steinbach, Kamalendra Singh, Bruno Marchand, Maxwell D Leslie, Ariel N Hagedorn, Eiichi N Kodama, Victor E Marquez, Stephen H Hughes, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Effects of 4' - and 2-Substitutions o... | |
| 2013 | Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Rita S Schildknecht, Hongtao Xu, Simani Gaseitswe, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg | The preferential selection of K65R in... | |
| 2013 | Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno Marchand, Maxwell D Leslie, Andrew D Huber, Yee Tsuey Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Hypersusceptibility mechanism of Teno... | |
| 2013 | Matthew McCallum, Maureen Oliveira, Ruxandra-Ilinca Ibanescu, Victor G Kramer, Daniela D Moisi, Eugene L Asahchop, Bluma G Brenner, Richard Harrigan, Hongtao Xu, Mark A. Wainberg | Basis for the Early and Preferential ... | |
| 2013 | Shiqiong Yang, Christophe Pannecouque, Dirk Daelemans, Xiao-Dong Ma, Yang Liu, Fen-Er Chen, Erik De Clercq | Molecular design, synthesis and biolo... | |
| 2013 | Xuwang Chen, Yuanyuan Li, Shufang Ding, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Huiqing Liu, Xinyong Liu | Discovery of Piperidine-Linked Pyridi... | |
| 2013 | Kalyan Das, Edward Arnold | HIV-1 reverse transcriptase and antiv... | |
| 2013 | Kalyan Das, Edward Arnold | HIV-1 reverse transcriptase and antiv... | |
| 2013 | J-H Lee, Atsuko Hachiya, S-K Shin, J Lee, Hiroyuki Gatanaga, Shinichi Oka, Karen A Kirby, Yee Tsuey Ong, Stefan G Sarafianos, William R Folk, Wangdon Yoo, Sun Pyo Hong, S-O Kim | Restriction fragment mass polymorphis... | |
| 2013 | Daniel G Kuroda, Joseph David Bauman, J Reddy Challa, Disha Patel, Thomas Troxler, Kalyan Das, Edward Arnold, Robin M Hochstrasser | Snapshot of the equilibrium dynamics ... | |
| 2013 | Dongyue Li, Peng Zhan, Huiqing Liu, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2013 | Mikhail S Novikov, Vladimir T Valuev-Elliston, Denis A Babkov, Maria P Paramonova, Alexander V Ivanov, Sergey A Gavryushov, Anastasia L Khandazhinskaya, Sergey N Kochetkov, Christophe Pannecouque, Graciela Andrei, Robert Snoeck, Jan Balzarini, Katherine L Seley-Radtke | N(1),N(3)-disubstituted uracils as no... | |
| 2013 | John E Tavis, Xiaohong Cheng, Yuan Hu, Michael Totten, Feng Cao, Eleftherios Michailidis, Rajeev Aurora, Marvin J Meyers, E Jon Jacobsen, Michael A. Parniak, Stefan G Sarafianos | The hepatitis B virus ribonuclease h ... | |
| 2013 | Joseph David Bauman, Disha Patel, Chhaya Dharia, Marc Fromer, Sameer Ahmed, Yulia Volovik Frenkel, J Thomas Eck, William C Ho, Kalyan Das, Aaron J Shatkin, Edward Arnold | Detecting allosteric sites of HIV-1 r... | |
| 2013 | Hong-Tao Xu, Susan P Colby-Germinario, Eugene L Asahchop, Maureen Oliveira, Matthew McCallum, Susan M Schader, Yingshan Han, Yudong Quan, Stefan G Sarafianos, Mark A. Wainberg | The Effect of Mutations at Position E... | |
| 2013 | Ravindra K Gupta, DA Van de Vijver, S Manicklal, MA Wainberg | Evolving uses of oral reverse transcr... | |
| 2013 | A Heredia, CE Davis, MS Reitz, NM Le, MA Wainberg, JS Foulke, LX Wang, RR Redfield | Targeting of the Purine Biosynthesis ... | |
| 2013 | Hai-Qiu Wu, Zi-Hong Yan, Wen-Xue Chen, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Dirk Daelemans, Christophe Pannecouque | Towards new C6-rigid S-DABO HIV-1 rev... | |
| 2013 | Linda L Dunn, Paul L Boyer, Patrick K Clark, Stephen H Hughes | Mutations in HIV-1 reverse transcript... | |
| 2013 | Jan Balzarini, Graciela Andrei, Emanuela Balestra, Dana Huskens, Christophe Vanpouille, Andrea Introini, Sonia Zicari, Sandra Liekens, Robert Snoeck, Antonín Holý, CF Perno, Leonid Margolis, Dominique Schols | A Multi-targeted Drug Candidate with ... | |
| 2013 | Erik De Clercq | The Nucleoside Reverse Transcriptase ... | |
| 2013 | Ye Tian, Diwakar Rai, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Huiqing Liu, Xinyong Liu | Design, Synthesis, and Biological Eva... | |
| 2012 | Christal D Sohl, Rajesh Kasiviswanathan, Jiae Kim, Ugo Pradere, Raymond F Schinazi, William C Copeland, Hiroyuki Mitsuya, Masanori Baba, Karen S Anderson | Balancing Antiviral Potency and Host ... | |
| 2012 | Marco Radi, Mafalda Pagano, Luigi Franchi, Daniele Castagnolo, Silvia Schenone, Gianni Casaluce, Claudio Zamperini, Elena Dreassi, Giovanni Maga, Alberta Samuele, Encarna Gonzalo, B Clotet, José A Esté, Maurizio Botta | Synthesis, Biological Activity, and A... | |
| 2012 | Paul L Boyer, Patrick K Clark, Stephen H Hughes | HIV-1 and HIV-2 Reverse Transcriptase... | |
| 2012 | Shuang-Xi Gu, Zhi-Ming Li, Xiao-Dong Ma, Shi-Qiong Yang, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Chiral resolution, absolute configura... | |
| 2012 | Wenwen Chen, Peng Zhan, Erik De Clercq, Xinyong Liu | Recent progress in small molecule CCR... | |
| 2012 | Kalyan Das, Sergio E Martinez, Joseph David Bauman, Edward Arnold | HIV-1 reverse transcriptase complex w... | |
| 2012 | Changfu Yang, Shuyuan Liu, Taisong Zhang, Yaping Hou, Xiaoli Liu, Yun Gao, Guang Yang, Zhen Wang, Huayun Chen, Ming Li, Zhenyu Zhu | Transmitted antiretroviral drug resis... | |
| 2012 | Peng Zhan, Xincang Li, Zhongjie Li, Xuwang Chen, Ye Tian, Wenmin Chen, Xinyong Liu, Christophe Pannecouque, Erik De Clercq | Structure-based bioisosterism design,... | |
| 2012 | Victor G Kramer, Susan M Schader, Maureen Oliveira, Susan P Colby-Germinario, Daniel A Donahue, Diane N Singhroy, Randy Tressler, Richard D Sloan, Mark A. Wainberg | Maraviroc and other HIV-1 entry inhib... | |
| 2012 | Ye Tian, Peng Zhan, Diwakar Rai, Jiyan Zhang, Erik De Clercq, Xinyong Liu | Recent advances in the research of 2,... | |
| 2012 | Atsuko Hachiya, Bruno Marchand, Karen A Kirby, Eleftherios Michailidis, Xiongying Tu, Krzysztof Palczewski, Yee Tsuey Ong, Zhongjie Li, Daniel T Griffin, Matthew M Schuckmann, Junko Tanuma, Shinichi Oka, Kamalendra Singh, Eiichi N Kodama, Stefan G Sarafianos | HIV-1 reverse transcriptase (RT) poly... | |
| 2012 | Kamalendra Singh, Bruno Marchand, Devendra K Rai, Bechan Sharma, Eleftherios Michailidis, Emily M Ryan, Kayla B Matzek, Maxwell D Leslie, Ariel N Hagedorn, Zhongjie Li, Pieter R Norden, Atsuko Hachiya, Michael A. Parniak, Hong-Tao Xu, Mark A. Wainberg, Stefan G Sarafianos | Biochemical Mechanism of HIV-1 Resist... | |
| 2012 | Xuwang Chen, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2012 | Martin T Christen, Lakshmi Menon, Nataliya S Myshakina, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima | Structural basis of the allosteric in... | |
| 2012 | Dante Rotili, Alberta Samuele, Domenico Tarantino, Rino Ragno, Ira Musmuca, Flavio Ballante, Giorgia Botta, Ludovica Morera, Marco Pierini, Roberto Cirilli, Maxim B Nawrozkij, Emmanuel Gonzalez, B Clotet, Marino Artico, José A Esté, Giovanni Maga, Antonello Mai | 2-(Alkyl/Aryl)Amino-6-Benzylpyrimidin... | |
| 2012 | Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd | DNA Polymerase β Gap-filling Transles... | |
| 2012 | Xincang Li, Peng Zhan, Erik De Clercq, Xinyong Liu | The HIV-1 Non-Nucleoside Reverse Tran... | |
| 2012 | Barry C Johnson, Gary T Pauly, Ganesha Rai, Disha Patel, Joseph David Bauman, Heather L Baker, Kalyan Das, Joel P Schneider, David J Maloney, Edward Arnold, Craig J Thomas, Stephen H Hughes | A comparison of the ability of rilpiv... | |
| 2012 | Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valeria Famiglini, Sandro Cosconati, Giovanni Maga, Alberta Samuele, Emmanuel Gonzales, B Clotet, Dominique Schols, Jose Este, Ettore Novellino, Romano Silvestri | New Nitrogen Containing Substituents ... | |
| 2012 | K O François, Jan Balzarini | Potential of carbohydrate-binding age... | |
| 2012 | Karen A Kirby, Bruno Marchand, Yee Tsuey Ong, Tanyaradzwa P Ndongwe, Atsuko Hachiya, Eleftherios Michailidis, Maxwell D Leslie, Daniel V Sietsema, Tracy L Fetterly, Christopher A Dorst, Kamalendra Singh, Zhengqiang Wang, Michael A. Parniak, Stefan G Sarafianos | Structural and Inhibition Studies of ... | |
| 2012 | Christophe Vanpouille, Andrea Lisco, Andrea Introini, Jean-Charles Grivel, Arshi Munawwar, Melanie Merbah, Raymond F Schinazi, Marco Derudas, Christopher McGuigan, Jan Balzarini, Leonid Margolis | Exploiting the anti-HIV-1 activity of... | |
| 2012 | Serdal Kirmizialtin, Virginia Nguyen, Kenneth A Johnson, Ron Elber | How conformational dynamics of DNA po... | |
| 2012 | Dongyue Li, Peng Zhan, Erik De Clercq, Xinyong Liu | Strategies for the design of HIV-1 no... | |
| 2012 | Xuwang Chen, Peng Zhan, Xin Liu, Ziheng Cheng, Caicai Meng, Siyuan Shao, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Design, synthesis, anti-HIV evaluatio... | |
| 2012 | Eva-María Priego, Anna Karlsson, Federico Gago, María-José Camarasa, Jan Balzarini, María-Jesús Pérez-Pérez | Recent advances in thymidine kinase 2... | |
| 2012 | Eleftherios Michailidis, Kamlendra Singh, Emily M Ryan, Atsuko Hachiya, Yee Tsuey Ong, Karen A Kirby, Bruno Marchand, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Effect of translocation defective rev... | |
| 2012 | Sergio R Ribone, Volker Leen, Marcela Madrid, Wim Dehaen, Dirk Daelemans, Christophe Pannecouque, Margarita C Briñón | Synthesis, biological evaluation and ... | |
| 2012 | Peng Zhan, Wenmin Chen, Zhongjie Li, Xincang Li, Xuwang Chen, Ye Tian, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Discovery of novel 2-(3-(2-chlorophen... | |
| 2012 | Tatiana Ilina, Krystal Labarge, Stefan G Sarafianos, Rieko Ishima, Michael A. Parniak | Inhibitors of HIV-1 Reverse Transcrip... | |
| 2012 | Wei-Shau Hu, Stephen H Hughes | HIV-1 Reverse Transcription. | |
| 2012 | Zhongjie Li, Yuan Cao, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Arylazolylthioacetanilide. Part 11: D... | |
| 2012 | Shiqiong Yang, Fen-Er Chen, Erik De Clercq | Dihydro-alkoxyl-benzyl-oxopyrimidine ... | |
| 2011 | Brian D Herman, Raymond F Schinazi, Hong-Wang Zhang, James H Nettles, Richard Stanton, Mervi Detorio, Aleksandr Obikhod, Ugo Pradère, Steven J Coats, John W Mellors, Nicolas Sluis-Cremer | Substrate mimicry: HIV-1 reverse tran... | |
| 2011 | Kalyan Das, Joseph David Bauman, Angela S Rim, Chhaya Dharia, Arthur D Clark, María-José Camarasa, Jan Balzarini, Edward Arnold | Crystal structure of tert-butyldimeth... | |
| 2011 | Jing-Rong Ye, Lei Guo, Hong-Yan Lu, Ruo-Lei Xin, Yi Zeng | [Genotypic resistance mutations to an... | |
| 2011 | Joseph David Bauman, Disha Patel, Edward Arnold | Fragment Screening and HIV Therapeutics. | |
| 2011 | Xuwang Chen, Peng Zhan, Dongyue Li, Erik De Clercq, Xinyong Liu | Recent advances in DAPYs and related ... | |
| 2011 | Peng Zhan, Xuwang Chen, Dongyue Li, Zengjun Fang, Erik De Clercq, Xinyong Liu | HIV-1 NNRTIs: Structural diversity, p... | |
| 2011 | Jing Zhang, Peng Zhan, Jingde Wu, Zhongjie Li, Yan Jiang, Weiying Ge, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2011 | María-Cruz Bonache, Alessandra Cordeiro, Ernesto Quesada, Els Vanstreels, Dirk Daelemans, María-José Camarasa, Jan Balzarini, Ana San-Félix | Selective inhibition of Human Immunod... | |
| 2011 | Tao Dong, Yongqing Zhang, Ke Yi Xu, Huiping Yan, Ian James, Yanchun Peng, Marie-Eve Blais, Silvana Gaudieri, Xinyue Chen, Wenhui Lun, Hao Wu, Wen Yan Qu, Tim Rostron, Ning Li, Yu Mao, Simon Mallal, Xiaoning Xu, Andrew McMichael, Mina John, Sarah L Rowland-Jones | Extensive HLA-driven viral diversity ... | |
| 2011 | Qingguo Gong, Lakshmi Menon, Tatiana Ilina, Lena G Miller, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima | Interaction of HIV-1 reverse transcri... | |
| 2011 | Yuan Yuan, Hui Xing, Xiao-Yu Wang, Chun-hua Liu, Li-Ting Yang, Ben-Feng Zheng, Xia Wang, Yu-Hua Ruan, Zhe Wang, Hong-wei Liu, Yi-ming Shao | [The prevalence of HIV-1 drug resista... | |
| 2011 | Eugene L Asahchop, Maureen Oliveira, Mark A. Wainberg, Bluma G Brenner, Daniela D Moisi, Thomas D'Aquin Toni, Cecile L Tremblay | Characterization of the E138K resista... | |
| 2011 | Hong-Tao Xu, Eugene L Asahchop, Maureen Oliveira, Peter K Quashie, Yudong Quan, Bluma G Brenner, Mark A. Wainberg | Compensation by the E138K mutation in... | |
| 2011 | Bluma G Brenner, Matthew Lowe, Daniela D Moisi, Isabelle Hardy, Simon Gagnon, Hugues Charest, Jean Guy Baril, Mark A. Wainberg, Michel Roger | Subtype diversity associated with the... | |
| 2011 | Alberta Samuele, Sara Bisi, Alexandra Kataropoulou, Giuseppe La Regina, Francesco Piscitelli, Valerio Gatti, Romano Silvestri, Giovanni Maga | Mechanism of interaction of novel ind... | |
| 2011 | Mark A. Wainberg, Daniela D Moisi, Maureen Oliveira, Thomas D'Aquin Toni, Bluma G Brenner | Transmission dynamics of the M184V dr... | |
| 2011 | Erik De Clercq | A 40-year journey in search of select... | |
| 2011 | Mingyan Yu, Zhongjie Li, Shuai Liu, Erkang Fan, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2011 | Graciela Andrei, Andrea Lisco, Christophe Vanpouille, Andrea Introini, Emanuela Balestra, Joost van den Oord, Tomas Cihlar, CF Perno, Robert Snoeck, Leonid Margolis, Jan Balzarini | Topical tenofovir, a microbicide effe... | |
| 2011 | Peibin Zeng, Jingxing Wang, Yi Huang, Xiaoming Guo, Jinming Li, Guoxin Wen, Tonghan Yang, Zhongqiao Yun, Miao He, Yu Liu, Yuzhe Yuan, Jane Schulmann, Simone Glynn, Paul Ness, J Brooks Jackson, Hua Shan | The human immunodeficiency virus-1 ge... | |
| 2011 | O Jegede, A Khodyakova, M Chernov, J Weber, L Menéndez-Arias, A Gudkov, ME Quiñones-Mateu | Identification of low-molecular weigh... | |
| 2011 | Mikhail S Novikov, Olga N Ivanova, Alexander V Ivanov, Alexander A Ozerov, Vladimir T Valuev-Elliston, Kartik Temburnikar, Galina V Gurskaya, Sergey N Kochetkov, Christophe Pannecouque, Jan Balzarini, Katherine L Seley-Radtke | 1-[2-(2-Benzoyl- and 2-benzylphenoxy)... | |
| 2011 | Xiao-Dong Ma, Shi-Qiong Yang, Shuang-Xi Gu, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV activity of ar... | |
| 2011 | Dimitrios Coutsinos, Cédric F Invernizzi, Daniela D Moisi, Maureen Oliveira, Jorge L Martinez-Cajas, Bluma G Brenner, Mark A. Wainberg | A template-dependent dislocation mech... | |
| 2011 | Karen A Kirby, Kamalendra Singh, Eleftherios Michailidis, Bruno Marchand, Eiichi N Kodama, Noriyuki Ashida, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | The sugar ring conformation of 4'-eth... | |
| 2011 | Zhinan Jin, Jerome Deval, Kenneth A Johnson, David C Swinney | Characterization of the elongation co... | |
| 2011 | Dante Rotili, Domenico Tarantino, Marino Artico, Maxim B Nawrozkij, Emmanuel Gonzalez-Ortega, B Clotet, Alberta Samuele, José A Esté, Giovanni Maga, Antonello Mai | Diarylpyrimidine-dihydrobenzyloxopyri... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Mathieu Metifiot, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | 3-Hydroxypyrimidine-2,4-diones as an ... | |
| 2011 | Claudette S Satchell, Jane A O'Halloran, Aoife G Cotter, Aaron J Peace, Eileen F O'Connor, Anthony F Tedesco, Eoin R Feeney, John S Lambert, Gerard J Sheehan, Dermot Kenny, Patrick W G Mallon | Increased Platelet Reactivity in HIV-... | |
| 2011 | Han-Ping Li, Wei Guo, Yong-Jian Liu, Zuo-Yi Bao, Lin Li, Dao-Min Zhuang, Si-Yang Liu, Zhengqiang Wang, Xiao-Lin Wang, Jing-Yun Li | [Screening program on novel drug resi... | |
| 2011 | Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valerio Gatti, Giovanni Maga, Alberta Samuele, Christophe Pannecouque, Dominique Schols, Jan Balzarini, Ettore Novellino, Romano Silvestri | Indolylarylsulfones as HIV-1 non-nucl... | |
| 2011 | Mark A Ditzler, Debojit Bose, Nikolozi Shkriabai, Bruno Marchand, Stefan G Sarafianos, Mamuka Kvaratskhelia, Donald H Burke | Broad-spectrum aptamer inhibitors of ... | |
| 2011 | Stefania Butini, Sandra Gemma, Margherita Brindisi, Giuseppe Borrelli, Isabella Fiorini, Alberta Samuele, Aristotele Karytinos, Marcella Facchini, Andrea Lossani, Samantha Zanoli, Giuseppe Campiani, Ettore Novellino, Federico Focher, Giovanni Maga | Enantioselective binding of second ge... | |
| 2011 | Allison K Delong, Mingham Wu, Diane Bennett, Neil Parkin, Zhijin Wu, Joseph W Hogan, Rami Kantor | Sequence Quality Analysis Tool (SQUAT... | |
| 2011 | Tanyaradzwa P Ndongwe, Adeyemi O Adedeji, Eleftherios Michailidis, Yee Tsuey Ong, Atsuko Hachiya, Bruno Marchand, Emily M Ryan, Devendra K Rai, Karen A Kirby, Angela S Whatley, Donald H Burke, Marc Johnson, Shilei Ding, Yi-Min Zheng, Shan-Lu Liu, Ei-Ichi Kodama, Krista A Delviks-Frankenberry, Vinay K Pathak, Hiroyuki Mitsuya, Michael A. Parniak, Kamalendra Singh, Stefan G Sarafianos | Biochemical, inhibition and inhibitor... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | 6-Benzoyl-3-hydroxypyrimidine-2,4-dio... | |
| 2011 | Atsuko Hachiya, Eiichi N Kodama, Matthew M Schuckmann, Karen A Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G Sarafianos | K70Q adds high-level tenofovir resist... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | N-3 Hydroxylation of Pyrimidine-2,4-d... | |
| 2011 | Matthew W Kellinger, Kenneth A Johnson | Role of induced fit in limiting discr... | |
| 2011 | Brian J Scarth, Kirsten L White, James M Chen, Eric B Lansdon, S Swaminathan, Michael D Miller, Matthias Götte | Mechanism of resistance to GS-9148 co... | |
| 2011 | Brian J Scarth, Suzanne McCormick, Matthias Götte | Effects of mutations F61A and A62V in... | |
| 2011 | Chandravanu Dash, Yousef Ahmadibeni, Michael J Hanley, Jui Pandhare, Mathias Gotte, Stuart F J Le Grice, Keykavous Parang | Inhibition of multi-drug resistant HI... | |
| 2011 | Anick Auger, Greg L Beilhartz, Siqi Zhu, Elizabeth Cauchon, Jean-Pierre Falgueyret, Jay A Grobler, Maryam Ehteshami, Matthias Götte, Roman A Melnyk | Impact of primer-induced conformation... | |
| 2011 | Matthias Götte | Initiation of HIV reverse transcripti... | |
| 2011 | Suhman Chung, Daniel M Himmel, Jian-Kang Jiang, Krzysztof Wojtak, Joseph David Bauman, Jason W Rausch, Jennifer A Wilson, John A Beutler, Craig J Thomas, Edward Arnold, Stuart F J Le Grice | Synthesis, activity, and structural a... | |
| 2011 | Anthony K Felts, Krystal Labarge, Joseph David Bauman, Dishaben V Patel, Daniel M Himmel, Edward Arnold, Michael A. Parniak, Ronald M Levy | Identification of alternative binding... | |
| 2011 | Suhman Chung, Jennifer T Miller, Barry C Johnson, Stephen H Hughes, Stuart F J Le Grice | Mutagenesis of the human immunodefici... | |
| 2010 | Xiongying Tu, Kalyan Das, Qianwei Han, Joseph David Bauman, Arthur D Clark, Xiaorong Hou, Yulia Volovik Frenkel, Barbara L Gaffney, Roger A Jones, Paul L Boyer, Stephen H Hughes, Stefan G Sarafianos, Edward Arnold | Structural basis of HIV-1 resistance ... | |
| 2010 | Yuhua Ruan, Hui Xing, Xia Wang, Heng Tang, Zhengqiang Wang, Hongwei Liu, Bin Su, Jianjun Wu, Hanping Li, Lingjie Liao, Jinming Li, Julia Wei Wu, Yiming Shao | Virologic outcomes of first-line HAAR... | |
| 2010 | Eric B Lansdon, Katherine M Brendza, Magdeleine Hung, Ruth Wang, Susmith Mukund, Debi Jin, Gabriel Birkus, Nilima Kutty, Xiaohong Liu | Crystal structures of HIV-1 reverse t... | RT,Associated condition,All properties |
| 2010 | John C Martin, Michael J M Hitchcock, Erik De Clercq, William H Prusoff | Early nucleoside reverse transcriptas... | |
| 2010 | Anna-Maria Monforte, Patrizia Logoteta, Laura De Luca, Nunzio Iraci, Stefania Ferro, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Novel 1,3-dihydro-benzimidazol-2-ones... | |
| 2010 | Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq | 1,2,3-thiadiazole thioacetanilides. P... | |
| 2010 | Li-Jia Xu, Zong-Gen Peng, Hong-Shan Chen, Jie Wang, Pei-Gen Xiao | Bioactive triterpenoids from Kadsura ... | |
| 2010 | Viktor von Wyl, Maryam Ehteshami, Lisa M Demeter, Philippe Bürgisser, Monique Nijhuis, Jori Symons, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard | HIV-1 reverse transcriptase connectio... | |
| 2010 | Matthias Götte, Jason W Rausch, Bruno Marchand, Stefan G Sarafianos, Stuart F J Le Grice | Reverse transcriptase in motion: conf... | |
| 2010 | Pankaj R Daga, Jinsong Duan, Robert J Doerksen | Computational model of hepatitis B vi... | |
| 2010 | Brian D Herman, Ivan Votruba, Antonin Holy, Nicolas Sluis-Cremer, Jan Balzarini | The acyclic 2,4-diaminopyrimidine nuc... | |
| 2010 | Suhman Chung, Michaela Wendeler, Jason W Rausch, Greg L Beilhartz, Matthias Gotte, Barry R O'Keefe, Alun Bermingham, John A Beutler, Shixin Liu, Xiaowei Zhuang, Stuart F J Le Grice | Structure-activity analysis of vinylo... | |
| 2010 | Séverine Freisz, Guillaume Bec, Marco Radi, Philippe Wolff, Emmanuele Crespan, Lucilla Angeli, Philippe Dumas, Giovanni Maga, Maurizio Botta, Eric Ennifar | Crystal Structure of HIV-1 Reverse Tr... | RT,All properties |
| 2010 | Eric B Lansdon, Dharmaraj Samuel, Leanna Lagpacan, Katherine M Brendza, Kirsten L White, Magdeleine Hung, Xiaohong Liu, Constantine G Boojamra, Richard L Mackman, Tomas Cihlar, Adrian S Ray, Mary E McGrath, S Swaminathan | Visualizing the molecular interaction... | RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Polymerase Catalytic Residue Amino Acids,Residues Involved in Catalysis of RNase H,Incorporation of non-standard nucleotides,All properties |
| 2010 | Guido van Marle, Deirdre L Church, Kali D Nunweiler, Kris Cannon, Mark A. Wainberg, M John Gill | Higher levels of Zidovudine resistant... | |
| 2010 | Wujie Li, Mou Cao, Lu Pei, Xiaomei Ling, Bingchao Li, Zhenjun Yang | Study on steady-state kinetics of nuc... | RT,All properties |
| 2010 | Zhengqiang Wang, Jing Tang, Christine E Salomon, Christine D Dreis, Robert Vince | Pharmacophore and structure-activity ... | |
| 2010 | Giovanni Maga, Marco Radi, Marie-Aline Gerard, Maurizio Botta, Eric Ennifar | HIV-1 RT Inhibitors with a Novel Mech... | |
| 2010 | Hua-Poo Su, Youwei Yan, G Sridhar Prasad, Robert F Smith, Christopher L Daniels, Pravien D Abeywickrema, John C Reid, H Marie Loughran, Maria Kornienko, Sujata Sharma, Jay A Grobler, Bei Xu, Vinod Sardana, Timothy J Allison, Peter D Williams, Paul L Darke, Daria J Hazuda, Sanjeev Munshi | Structural basis for the inhibition o... | RT,RNase H,All properties |
| 2010 | Erik De Clercq | Antiretroviral drugs. | |
| 2010 | Matthew M Schuckmann, Bruno Marchand, Atsuko Hachiya, Eiichi N Kodama, Karen A Kirby, Kamalendra Singh, Stefan G Sarafianos | The N348I mutation at the connection ... | |
| 2010 | Hong-Tao Xu, Yudong Quan, Eugene L Asahchop, Maureen Oliveira, Daniella Moisi, Mark A. Wainberg | Comparative biochemical analysis of r... | |
| 2010 | Michael E Abram, Andrea L Ferris, Wei Shao, W Gregory Alvord, Stephen H Hughes | Nature, position, and frequency of mu... | |
| 2010 | Matthew W Kellinger, Kenneth A Johnson | Nucleotide-dependent conformational c... | RT,All properties |
| 2010 | Guozhi Tang, Denis J Kertesz, Minmin Yang, Xianfeng Lin, Zhengqiang Wang, Wentao Li, Zongxing Qiu, Junli Chen, Jianghua Mei, Li Chen, Taraneh Mirzadegan, Seth F Harris, Armando G Villaseñor, Jennifer Fretland, William L Fitch, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp | Exploration of piperidine-4-yl-aminop... | |
| 2010 | Michael L Mitchell, Jong Chan Son, Hongyan Guo, Yun-A Im, Eun Jung Cho, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Doris Graupe, Gerry Rhodes, Gong-Xin He, Romas Geleziunas, Lianhong Xu, Choung U Kim | N1-Alkyl pyrimidinediones as non-nucl... | RT,All properties |
| 2010 | H Nina Kim, Jing Wang, James Hughes, Robert Coombs, Jorge Sanchez, Stewart Reid, Sinead Delany-Moretlwe, Frances Cowan, Jonathan Fuchs, Susan H Eshleman, Leila Khaki, Moira A McMahon, Robert F Siliciano, Anna Wald, Connie Celum | Effect of acyclovir on HIV-1 set poin... | |
| 2010 | Alberta Samuele, Emmanuele Crespan, Samanta Vitellaro, Anna-Maria Monforte, Patrizia Logoteta, Alba Chimirri, Giovanni Maga | Slow binding-tight binding interactio... | |
| 2010 | Mia J Biondi, Greg L Beilhartz, Suzanne McCormick, Matthias Götte | N348I in HIV-1 reverse transcriptase ... | |
| 2010 | Greg L Beilhartz, Matthias Götte | HIV-1 Ribonuclease H: Structure, Cata... | |
| 2010 | Yong-Hong Liang, Qiu-Qin He, Zhao-Sen Zeng, Zhi-Qian Liu, Xiao-Qing Feng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq | Synthesis and anti-HIV activity of 2-... | |
| 2010 | Daniel A Donahue, Richard D Sloan, Björn D Kuhl, Tamara Bar-Magen, Susan M Schader, Mark A. Wainberg | Stage-dependent inhibition of HIV-1 r... | |
| 2010 | Viktor von Wyl, Maryam Ehteshami, Jori Symons, Philippe Bürgisser, Monique Nijhuis, Lisa M Demeter, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard | Epidemiological and biological eviden... | |
| 2010 | Hong-Tao Xu, Maureen Oliveira, Yudong Quan, Tamara Bar-Magen, Mark A. Wainberg | Differential impact of the HIV-1 non-... | |
| 2010 | Denis J Kertesz, Christine Brotherton-Pleiss, Minmin Yang, Zhengqiang Wang, Xianfeng Lin, Zongxing Qiu, Donald R Hirschfeld, Shelley K Gleason, Taraneh Mirzadegan, Pete W Dunten, Seth F Harris, Armando G Villaseñor, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp | Discovery of piperidin-4-yl-aminopyri... | RT,All properties |
| 2010 | Zhao-Sen Zeng, Qiu-Qin He, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Hybrid diarylbenzopyrimidine non-nucl... | |
| 2010 | Erik De Clercq | In search of a selective therapy of v... | |
| 2010 | Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Bluma G Brenner, Mark A. Wainberg | Factors affecting template usage in t... | |
| 2010 | Michael E Abram, Stefan G Sarafianos, Michael A. Parniak | The mutation T477A in HIV-1 reverse t... | |
| 2010 | Romuald Corbau, Julie Mori, Chris Phillips, Lesley Fishburn, Alex Martin, Charles Mowbray, Wendy Panton, Caroline Smith-Burchnell, Adele Thornberry, Heather Ringrose, Thorsten Knöchel, Steve Irving, Mike Westby, Anthony Wood, Manos Perros | Lersivirine: a Non-Nucleoside Reverse... | RT,All properties |
| 2010 | Zhao-Sen Zeng, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq | Lead optimization of diarylpyrimidine... | |
| 2010 | Michael L Mitchell, Jong Chan Son, Ill Young Lee, Chong-Kyo Lee, Hae Soo Kim, Hongyan Guo, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Gene Eisenberg, Romas Geleziunas, Lianhong Xu, Choung U Kim | N1-Heterocyclic pyrimidinediones as n... | RT,All properties |
| 2010 | Martin Di Grandi, Matthew Olson, Amar S Prashad, Geraldine Bebernitz, Amara Luckay, Stanley Mullen, Yongbo Hu, Girija Krishnamurthy, Keith Pitts, John O'Connell | Small molecule inhibitors of HIV RT R... | |
| 2009 | Thorsten A Kirschberg, Mini Balakrishnan, Neil H Squires, Tiffany Barnes, Katherine M Brendza, Xiaowu Chen, Eugene J Eisenberg, Weili Jin, Nilima Kutty, Stephanie Leavitt, Albert C Liclican, Qi Liu, Xiaohong Liu, John Mak, Jason K Perry, Michael Wang, William J Watkins, Eric B Lansdon | RNase H active site inhibitors of hum... | |
| 2009 | Dan Turner, Eduardo Shahar, Eugene Katchman, Eynat Kedem, Natasha Matus, Michal Katzir, Gamal Hassoun, Shimon Pollack, Rivka Kessner, Mark A. Wainberg, Boaz Avidor | Prevalence of the K65R resistance rev... | |
| 2009 | Dharmesh H Mahajan, Christophe Pannecouque, Erik De Clercq, Kishor H Chikhalia | Synthesis and studies of new 2-(couma... | |
| 2009 | Erik De Clercq | A new drug combination therapy for tr... | |
| 2009 | Marco Derudas, Davide Carta, Andrea Brancale, Christophe Vanpouille, Andrea Lisco, Leonid Margolis, Jan Balzarini, Christopher McGuigan | The application of phosphoramidate pr... | |
| 2009 | Erik De Clercq | Anti-HIV drugs: 25 compounds approved... | |
| 2009 | Peng Zhan, Zhongjie Li, Xinyong Liu, Erik De Clercq | Sulfanyltriazole/tetrazoles: a promis... | |
| 2009 | Paul L Boyer, B Christie Vu, Zandrea Ambrose, John G Julias, Svenja Warnecke, Chenzhong Liao, Chris Meier, Victor E Marquez, Stephen H Hughes | The nucleoside analogue D-carba T blo... | |
| 2009 | Anders Vahlne | A historical reflection on the discov... | |
| 2009 | Yoshiyuki Mizushina, Hirohisa Motoshima, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Ken Hirano, Fumio Sugawara, Hiromi Yoshida | 3-O-methylfunicone, a selective inhib... | |
| 2009 | Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2009 | Yong-Hong Liang, Xiao-Qing Feng, Zhao-Sen Zeng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq | Design, synthesis, and SAR of naphthy... | |
| 2009 | Peng Zhan, Xinyong Liu, Zengjun Fang, Christophe Pannecouque, Erik De Clercq | 1,2,3-Selenadiazole thioacetanilides:... | |
| 2009 | Hironori Nishitsuji, Takaya Hayashi, Tomosaburo Takahashi, Masashi Miyano, Mari Kannagi, Takao Masuda | Augmentation of reverse transcription... | |
| 2009 | Alexandra Kataropoulou, Chiara Bovolenta, Amalia Belfiore, Sonia Trabatti, Anna Garbelli, Simona Porcellini, Rossella Lupo, Giovanni Maga | Mutational analysis of the HIV-1 auxi... | |
| 2009 | Alberta Samuele, Alexandra Kataropoulou, Marco Viola, Samantha Zanoli, Giuseppe La Regina, Francesco Piscitelli, Romano Silvestri, Giovanni Maga | Non-nucleoside HIV-1 reverse transcri... | |
| 2009 | Peng Zhan, Xinyong Liu, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Design strategies of novel NNRTIs to ... | |
| 2009 | Peng Zhan, Xinyong Liu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Synthesis and anti-HIV activity evalu... | |
| 2009 | Takuma Kimura, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Eiji Ohashi, Haruo Ohmori, Chikahide Masutani, Fumio Hanaoka, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Penicilliols A and B, novel inhibitor... | |
| 2009 | Marco Radi, Giovanni Maga, Maddalena Alongi, Lucilla Angeli, Alberta Samuele, Samantha Zanoli, Luca Bellucci, Andrea Tafi, Gianni Casaluce, Gianluca Giorgi, Mercedes Armand-Ugon, Emmanuel Gonzalez, José A Esté, Mireille Baltzinger, Guillaume Bec, Philippe Dumas, Eric Ennifar, Maurizio Botta | Discovery of chiral cyclopropyl dihyd... | |
| 2009 | Stefania Butini, Margherita Brindisi, Sandro Cosconati, Luciana Marinelli, Giuseppe Borrelli, Salvatore Sanna Coccone, Anna Ramunno, Giuseppe Campiani, Ettore Novellino, Samantha Zanoli, Alberta Samuele, Gianluca Giorgi, Alberto Bergamini, Michela Di Mattia, Silvana Lalli, Bruno Galletti, Sandra Gemma, Giovanni Maga | Specific targeting of highly conserve... | |
| 2009 | Kazuki Izumi, Eiichi N Kodama, Kazuya Shimura, Yasuko Sakagami, Kentaro Watanabe, Saori Ito, Tsuyoshi Watabe, Yukihiro Terakawa, Hiroki Nishikawa, Stefan G Sarafianos, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka | Design of peptide-based inhibitors fo... | |
| 2009 | L Menéndez-Arias | Mutation Rates and Intrinsic Fidelity... | Frameshift Error Rate,All properties |
| 2009 | Young-Sam Lee, W Dexter Kennedy, Y Whitney Yin | Structural insight into processive hu... | |
| 2009 | Greg L Beilhartz, Michaela Wendeler, Noel S Baichoo, Jason W Rausch, Stuart F J Le Grice, Matthias Götte | HIV-1 reverse transcriptase can simul... | |
| 2009 | Linda L Dunn, Mary Jane McWilliams, Kalyan Das, Edward Arnold, Stephen H Hughes | Mutations in the thumb allow human im... | |
| 2009 | Xuexiang Zhang, Xueyan Jiang, Hongzhou Lu, Fang Shen, Jiangrong Wang | Dyslipidaemia and Intima-Media Thickn... | |
| 2009 | Kristina A Paris, Omar Haq, Anthony K Felts, Kalyan Das, Edward Arnold, Ronald M Levy | Conformational landscape of the human... | |
| 2009 | Susan P Colby-Germinario, Adan Rios, Jorge Quesada, Dallas Anderson, Allan L Goldstein, Theresa Fossum, Mark A. Wainberg | HIV inactivation by cross-linking of ... | |
| 2009 | Atsuko Hachiya, Kazuki Shimane, Stefan G Sarafianos, Eiichi N Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi, Shinichi Oka | Clinical relevance of substitutions i... | |
| 2009 | Dai-Shi Su, John J Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J Felock, Meiqing Lu, Ming-Tain Lai, Sinoeun Touch, Gregory Moyer, Daniel J Distefano, Jessica A Flynn, Yuexia Liang, Rosa Sanchez, Sridhar Prasad, Youwei Yan, Rebecca A Perlow-Poehnelt, Maricel Torrent, Michael D Miller, Joe P Vacca, Theresa M Williams, Neville J Anthony | Substituted tetrahydroquinolines as p... | RT,All properties |
| 2009 | Anna-Maria Monforte, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Design, synthesis, and structure-acti... | |
| 2009 | Takeshi Naito, Kazuki Izumi, Eiichi N Kodama, Yasuko Sakagami, Keiko Kajiwara, Hiroki Nishikawa, Kentaro Watanabe, Stefan G Sarafianos, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka | SC29EK, a peptide fusion inhibitor wi... | |
| 2009 | Francesco Piscitelli, Antonio Coluccia, Andrea Brancale, Giuseppe La Regina, Anna Sansone, Cesare Giordano, Jan Balzarini, Giovanni Maga, Samantha Zanoli, Alberta Samuele, Roberto Cirilli, Francesco La Torre, Antonio Lavecchia, Ettore Novellino, Romano Silvestri | Indolylarylsulfones bearing natural a... | |
| 2009 | Matthew D Cullen, William C Ho, Joseph David Bauman, Kalyan Das, Edward Arnold, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Crystallographic study of a novel sub... | RT,All properties |
| 2009 | Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg | Signature nucleotide polymorphisms at... | |
| 2009 | Yudong Quan, Chen Liang, Bluma G Brenner, Mark A. Wainberg | Multidrug-resistant variants of HIV t... | |
| 2009 | Kalyan Das, Rajiv P Bandwar, Kirsten L White, Joy Y Feng, Stefan G Sarafianos, Steven Tuske, Xiongying Tu, Arthur D Clark, Paul L Boyer, Xiaorong Hou, Barbara L Gaffney, Roger A Jones, Michael D Miller, Stephen H Hughes, Edward Arnold | Structural basis for the role of the ... | RT,All properties |
| 2009 | Bo-Liang Deng, Yaofeng Zhao, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis of alkenyldiarylmethanes (A... | |
| 2009 | Daniel M Himmel, Karen A Maegley, Tom A Pauly, Joseph David Bauman, Kalyan Das, Chhaya Dharia, Arthur D Clark, Kevin Ryan, Michael J Hickey, Robert A Love, Stephen H Hughes, Simon Bergqvist, Edward Arnold | Structure of HIV-1 reverse transcript... | RT,RNase H,All properties |
| 2009 | MC Puertas, MJ Buzón, A Artese, S Alcaro, L Menéndez-Arias, CF Perno, B Clotet, F Ceccherini-Silberstein, J Martinez-Picado | Effect of the human immunodeficiency ... | |
| 2009 | Franck Chiappini, Elina Teicher, Raphaël Saffroy, Brigitte Debuire, Daniel Vittecoq, Antoinette Lemoine | Relationship between polymerase gamma... | |
| 2009 | Stefan G Sarafianos, Bruno Marchand, Kalyan Das, Daniel M Himmel, Michael A. Parniak, Stephen H Hughes, Edward Arnold | Structure and function of HIV-1 rever... | |
| 2009 | Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Daniela D Moisi, Maureen Oliveira, Bluma G Brenner, Mark A. Wainberg | Template usage is responsible for the... | |
| 2009 | Peng Zhan, Xinyong Liu, Junjie Zhu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Synthesis and biological evaluation o... | |
| 2009 | Egor P Tchesnokov, Aleksandr Obikhod, Ivana Massud, Andrea Lisco, Christophe Vanpouille, Beda Brichacek, Jan Balzarini, Christopher McGuigan, Marco Derudas, Leonid Margolis, Raymond F Schinazi, Matthias Götte | Mechanisms associated with HIV-1 resi... | |
| 2009 | Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and in vitro anti-HIV evalu... | |
| 2009 | Hongtao Xu, Yudong Quan, Bluma G Brenner, Tamara Bar-Magen, Maureen Oliveira, Susan M Schader, Mark A. Wainberg | Human immunodeficiency virus type 1 r... | |
| 2008 | Jangsuk Oh, Mary Jane McWilliams, John G Julias, Stephen H Hughes | Mutations in the U5 region adjacent t... | |
| 2008 | Alberta Samuele, Marcella Facchini, Dante Rotili, Antonello Mai, Marino Artico, Mercedes Armand-Ugón, José A Esté, Giovanni Maga | Substrate-induced stable enzyme-inhib... | |
| 2008 | Marco Radi, Chiara Falciani, Lorenzo Contemori, Elena Petricci, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Montserrat Terrazas, Marinunzia Castria, Andrea Togninelli, José A Esté, Imma Clotet-Codina, Mercedes Armand-Ugón, Maurizio Botta | A multidisciplinary approach for the ... | |
| 2008 | Bechan Sharma, Emmanuele Crespan, Giuseppe Villani, Giovanni Maga | The balance between the rates of inco... | |
| 2008 | Thomas J Tucker, Sandeep Saggar, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan | The design and synthesis of diaryl et... | RT,All properties |
| 2008 | Zachary K Sweeney, James P Dunn, Yingqian Li, Gabrielle M Heilek, Pete W Dunten, Todd R Elworthy, Xiaochun Han, Seth F Harris, Donald R Hirschfeld, J Heather Hogg, Walter Huber, Ann C Kaiser, Denis J Kertesz, Woongki Kim, Taraneh Mirzadegan, Michael G Roepel, Y David Saito, Tania M P C Silva, Steven Swallow, Jahari L Tracy, Armando Villasenor, Harit Vora, Amy S Zhou, Klaus Klumpp | Discovery and optimization of pyridaz... | RT,All properties |
| 2008 | Zhengqiang Wang, Robert Vince | Design and synthesis of dual inhibito... | |
| 2008 | Zhengqiang Wang, Robert Vince | Synthesis of pyrimidine and quinolone... | |
| 2008 | Yongcheng Song, Julian M W Chan, Zev Tovian, Aaron Secrest, Eva Nagy, Kilannin Krysiak, Kyle Bergan, Michael A. Parniak, Eric Oldfield | Bisphosphonate inhibitors of ATP-medi... | |
| 2008 | Anna-Maria Monforte, Angela Rao, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Maria Letizia Barreca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Novel N1-substituted 1,3-dihydro-2H-b... | |
| 2008 | Guangwei Yang, Jianhong Wang, Yao Cheng, Ginger E Dutschman, Hiromichi Tanaka, Masanori Baba, Yung-Chi Cheng | Mechanism of inhibition of human immu... | |
| 2008 | Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2008 | Lu Gao, Mark Nils Hanson, Mini Balakrishnan, Paul L Boyer, Bernard P Roques, Stephen H Hughes, Baek Kim, Robert A Bambara | Apparent defects in processive DNA sy... | |
| 2008 | Atsuko Hachiya, Eiichi N Kodama, Stefan G Sarafianos, Matthew M Schuckmann, Yasuko Sakagami, Masao Matsuoka, Masafumi Takiguchi, Hiroyuki Gatanaga, Shinichi Oka | Amino acid mutation N348I in the conn... | |
| 2008 | Thorsten A Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty, Albert C Liclican, Damian J McColl, Neil H Squires, Eric B Lansdon | Triazole derivatives as non-nucleosid... | RT,All properties |
| 2008 | Scott J Garforth, Michael A. Parniak, Vinayaka R Prasad | Utilization of a deoxynucleoside diph... | |
| 2008 | Joseph David Bauman, Kalyan Das, William C Ho, Mukta Baweja, Daniel M Himmel, Arthur D Clark, Deena A Oren, Paul L Boyer, Stephen H Hughes, Aaron J Shatkin, Edward Arnold | Crystal engineering of HIV-1 reverse ... | RT,All properties |
| 2008 | Zhijian Zhao, Scott E Wolkenberg, Philip E J Sanderson, Meiqing Lu, Vandna Munshi, Gregory Moyer, Meizhen Feng, Anthony V Carella, Linda T Ecto, Lori J Gabryelski, Ming-Tain Lai, Sridar G Prasad, Youwei Yan, Georgia B McGaughey, Michael D Miller, Craig W Lindsley, George D Hartman, Joseph P Vacca, Theresa M Williams | Novel indole-3-sulfonamides as potent... | RT,All properties |
| 2008 | Jingshan Ren, Phillip P Chamberlain, Anna Stamp, Steven A Short, Kurt L Weaver, Karen R Romines, Richard J Hazen, Andrew Freeman, Robert G Ferris, C Webster Andrews, Lawrence R Boone, Joseph H Chan, David K Stammers | Structural basis for the improved dru... | RT,All properties |
| 2008 | Bluma G Brenner, Michel Roger, Daniela D Moisi, Maureen Oliveira, Isabelle Hardy, Reuven Turgel, Hugues Charest, Jean-Pierre Routy, Mark A. Wainberg | Transmission networks of drug resista... | |
| 2008 | Patrick P Lestienne, François Boudsocq, Jacques E Bonnet | Initiation of DNA replication by a th... | |
| 2008 | Maryam Ehteshami, Brian J Scarth, Egor P Tchesnokov, Chandravanu Dash, Stuart F J Le Grice, Sabine Hallenberger, Dirk Jochmans, Matthias Götte | Mutations M184V and Y115F in HIV-1 re... | |
| 2008 | Peng Zhan, Xinyong Liu, Yuan Cao, Yan Wang, Christophe Pannecouque, Erik De Clercq | 1,2,3-Thiadiazole thioacetanilides as... | |
| 2008 | Ravindra K Rawal, Rajkamal Tripathi, Smitha Kulkarni, R Paranjape, S B Katti, Christophe Pannecouque, Erik De Clercq | 2-(2,6-Dihalo-phenyl)-3-heteroaryl-2-... | |
| 2008 | Maryam Ehteshami, Greg L Beilhartz, Brian J Scarth, Egor P Tchesnokov, Suzanne McCormick, Brian Wynhoven, P Richard Harrigan, Matthias Götte | Connection domain mutations N348I and... | |
| 2008 | Erik De Clercq | Emerging antiviral drugs. | |
| 2008 | Fang Yu, Xinyong Liu, Peng Zhan, Erik De Clercq | Recent advances in the research of HI... | |
| 2008 | Tatiana Ilina, Michael A. Parniak | Inhibitors of HIV-1 reverse transcrip... | |
| 2008 | Chong Fang, Joseph David Bauman, Kalyan Das, Amanda Remorino, Edward Arnold, Robin M Hochstrasser | Two-dimensional infrared spectra reve... | |
| 2008 | Andrea Lisco, Christophe Vanpouille, Egor P Tchesnokov, Jean-Charles Grivel, Angélique Biancotto, Beda Brichacek, Julie Elliott, Emilie Fromentin, Robin Shattock, Peter Anton, Robert Gorelick, Jan Balzarini, Christopher McGuigan, Marco Derudas, Matthias Götte, Raymond F Schinazi, Leonid Margolis | Acyclovir is activated into a HIV-1 r... | RT,All properties |
| 2008 | Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte | Delayed chain termination protects th... | |
| 2008 | Samir Abdurahman, Akos Végvári, Masoud Youssefi, Michael Levi, Stefan Höglund, Elin Andersson, Peter Horal, Bo Svennerholm, Jan Balzarini, Anders Vahlne | Activity of the small modified amino ... | |
| 2008 | Kalyan Das, Joseph David Bauman, Arthur D Clark, Yulia Volovik Frenkel, Paul J Lewi, Aaron J Shatkin, Stephen H Hughes, Edward Arnold | High-resolution structures of HIV-1 r... | RT,All properties |
| 2008 | Samantha Zanoli, Sandra Gemma, Stefania Butini, Margherita Brindisi, Bhupendra P Joshi, Giuseppe Campiani, Caterina Fattorusso, Marco Persico, Emmanuele Crespan, Reynel Cancio, Silvio Spadari, Ulrich Hübscher, Giovanni Maga | Selective targeting of the HIV-1 reve... | |
| 2008 | Michel L Ntemgwa, Thomas D'Aquin Toni, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Maureen Oliveira, Mark A. Wainberg | Near full-length genomic analysis of ... | |
| 2008 | Yueping Wang, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse-transcri... | |
| 2008 | Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and biological evaluation o... | |
| 2008 | Matthew D Cullen, York-Fong Cheung, Miles D Houslay, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Investigation of the alkenyldiarylmet... | |
| 2008 | Krista A Delviks-Frankenberry, Galina N Nikolenko, Paul L Boyer, Stephen H Hughes, John M Coffin, Abhay Jere, Vinay K Pathak | HIV-1 reverse transcriptase connectio... | |
| 2008 | Michaela Wendeler, Hsiu-Fang Lee, Alun Bermingham, Jennifer T Miller, Oleg Chertov, Marion K Bona, Noel S Baichoo, Maryam Ehteshami, John A Beutler, Barry R O'Keefe, Matthias Götte, Mamuka Kvaratskhelia, Stuart F J Le Grice | Vinylogous ureas as a novel class of ... | |
| 2008 | Maryam Ehteshami, Matthias Götte | Effects of mutations in the connectio... | |
| 2008 | Mitsuki Naganuma, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | 1-deoxyrubralactone, a novel specific... | |
| 2008 | Thomas J Tucker, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, John C Reid, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan | Discovery of 3-{5-[(6-amino-1H-pyrazo... | RT,All properties |
| 2008 | Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Design and synthesis of 2-(2,6-dibrom... | |
| 2008 | Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Marco Ponassi, Torsten Unge, Martino Bolognesi | Crystal structures of HIV-1 reverse t... | RT,All properties |
| 2008 | Zachary K Sweeney, Seth F Harris, Seth F Arora, Hassan Javanbakht, Yingqian Li, Jennifer Fretland, James P Davidson, J Roland Billedeau, Shelley K Gleason, Donald R Hirschfeld, Joshua J Kennedy-Smith, Taraneh Mirzadegan, Ralf Roetz, Mark Smith, Sarah Sperry, Judy M Suh, Jeffrey Wu, Stan Tsing, Armando G Villaseñor, Amber Paul, Guoping Su, Gabrielle M Heilek, Julie Qi Hang, Amy S Zhou, Jesper A Jernelius, Fang-Jie Zhang, Klaus Klumpp | Design of annulated pyrazoles as inhi... | RT,All properties |
| 2008 | Atsushi Kawamoto, Eiichi N Kodama, Stefan G Sarafianos, Yasuko Sakagami, Satoru Kohgo, Kenji Kitano, Noriyuki Ashida, Yuko Iwai, Hiroyuki Hayakawa, Hirotomo Nakata, Hiroyuki Mitsuya, Edward Arnold, Masao Matsuoka | 2'-deoxy-4'-C-ethynyl-2-halo-adenosin... | |
| 2008 | Roger G Ptak, Philippe A Gallay, Dirk Jochmans, Andrew P Halestrap, Urs T Ruegg, Luke A Pallansch, Michael D Bobardt, Marie-Pierre P De Béthune, Johan Neyts, Erik De Clercq, Jean-Maurice Dumont, Pietro Scalfaro, Kamel Besseghir, Roland M Wenger, Brigitte Rosenwirth | Inhibition of human immunodeficiency ... | |
| 2008 | Jiaping Lai, Jun Wang, Zongwei Cai | Nucleoside reverse transcriptase inhi... | |
| 2008 | Takuma Kimura, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Novel azaphilones, kasanosins A and B... | |
| 2008 | Chandravanu Dash, Brian J Scarth, Christopher Badorrek, Matthias Götte, Stuart F J Le Grice | Examining the ribonuclease H primer g... | |
| 2008 | Julie Lemay, Priscilla Maidou-Peindara, Reynel Cancio, Eric Ennifar, Gaël Coadou, Giovanni Maga, Jean-Christophe Rain, Richard Benarous, Lang Xia Liu | AKAP149 binds to HIV-1 reverse transc... | |
| 2007 | Takeshi Sakamoto, Matthew D Cullen, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis and anti-HIV activity of ne... | |
| 2007 | Silvia Bertagnolio, Luis Soto-Ramirez, Richard Pilon, Roberto Rodriguez, Monica Viveros, Luis Fuentes, P Richard Harrigan, Theresa Mo, Don Sutherland, Paul Sandstrom | HIV-1 drug resistance surveillance us... | |
| 2007 | Andrew J Low, Winnie W Y Dong, Dennison Chan, Tobias Sing, Ronald Swanstrom, Mark Jensen, Satish Pillai, Benjamin Good, P Richard Harrigan | Current V3 genotyping algorithms are ... | |
| 2007 | Celia K S Chui, Zabrina L Brumme, Chanson J Brumme, Benita Yip, Elizabeth J Phillips, Julio S G Montaner, P Richard Harrigan | A simple screening approach to reduce... | |
| 2007 | Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh, Eiichi N Kodama, Guangwei Yang, Christopher M Bailey, Satoru Kohgo, Hiroyuki Hayakawa, Masao Matsuoka, Karen S Anderson, Yung-Chi Cheng, Hiroyuki Mitsuya | Activity against human immunodeficien... | |
| 2007 | Kalyan Das, Stefan G Sarafianos, Arthur D Clark, Paul L Boyer, Stephen H Hughes, Edward Arnold | Crystal structures of clinically rele... | |
| 2007 | Clara E Cases-González, Sandra Franco, Miguel Angel Martínez, L Menéndez-Arias | Mutational patterns associated with t... | |
| 2007 | Krista A Delviks-Frankenberry, Galina N Nikolenko, Rebekah Barr, Vinay K Pathak | Mutations in human immunodeficiency v... | |
| 2007 | Adrian S Ray, Joy Y Feng, Eisuke Murakami, Chung K Chu, Raymond F Schinazi, Karen S Anderson | Interaction of 2'-deoxyguanosine trip... | |
| 2007 | Paul L Boyer, John G Julias, Zandrea Ambrose, Maqbool A Siddiqui, Victor E Marquez, Stephen H Hughes | The nucleoside analogs 4'C-methyl thy... | |
| 2007 | Marleen C D G Huigen, Loek de Graaf, Dirk Eggink, Rob Schuurman, Viktor Müller, Anna Stamp, David K Stammers, Charles A B Boucher, Monique Nijhuis | Evolution of a novel 5-amino-acid ins... | |
| 2007 | Katharina Skrabal, Andrew J Low, Winnie W Y Dong, Tobias Sing, Peter K Cheung, Fabrizio Mammano, P Richard Harrigan | Determining human immunodeficiency vi... | |
| 2007 | William C Drosopoulos, Vinayaka R Prasad | The active site residue Valine 867 in... | |
| 2007 | Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia K S Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P Richard Harrigan | Evidence of differential HLA class I-... | |
| 2007 | Bruno Marchand, Kirsten L White, John K Ly, Nicolas A Margot, Ruth Wang, Martin J McDermott, Michael D Miller, Matthias Götte | Effects of the translocation status o... | |
| 2007 | Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, Joseph H Chan, Jörg-Peter Kleim, David K Stammers | Relationship of potency and resilienc... | RT,All properties |
| 2007 | Shinji Kamisuki, Chisato Ishimaru, Kadohiro Onoda, Isoko Kuriyama, Noriko Ida, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Nodulisporol and Nodulisporone, novel... | |
| 2007 | Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J Low, Peter K Cheung, P Richard Harrigan, Thomas Lengauer, Francisco S Domingues | Structural descriptors of gp120 V3 lo... | |
| 2007 | P Richard Harrigan, Theresa Mo, Jennifer Hirsch, Zabrina L Brumme, Paula McKenna, Lee Bacheler | A 21-base pair insertion/duplication ... | |
| 2007 | Qianwei Han, Stefan G Sarafianos, Edward Arnold, Michael A. Parniak, Barbara L Gaffney, Roger A Jones | Synthesis of AZTpSpCX2ppSA and AZTpSp... | |
| 2007 | Zabrina L Brumme, Chanson J Brumme, Celia K S Chui, Theresa Mo, Brian Wynhoven, Conan K Woods, Bethany M Henrick, Robert S Hogg, Julio S G Montaner, P Richard Harrigan | Effects of human leukocyte antigen cl... | |
| 2007 | Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, David Moore, Benita Yip, Evan Wood, Julio S G Montaner | Continued improvement in survival amo... | |
| 2007 | Christian Castro, Eric D Smidansky, Kenneth R Maksimchuk, Jamie J Arnold, Victoria S Korneeva, Matthias Götte, William H Konigsberg, Craig E Cameron | Two proton transfers in the transitio... | |
| 2007 | Chanson J Brumme, P Richard Harrigan, Emma C Preston, Winnie W Y Dong, Brian Wynhoven, Carol Murphy, Julio S G Montaner | Transmission of drug-resistant HIV-1 ... | |
| 2007 | Elizabeth J Phillips, Sonia Gutiérrez, Natalie Jahnke, Benita Yip, Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, Julio S G Montaner | Determinants of nevirapine hypersensi... | |
| 2007 | Paul L Boyer, Carolyn R Stenbak, David Hoberman, Maxine L Linial, Stephen H Hughes | In vitro fidelity of the prototype pr... | Full length or truncated,Frameshift Error Rate,Nucleotide Substitution Rate,Overall Error Rate,All properties |
| 2007 | Tobias Sing, Andrew J Low, Niko Beerenwinkel, Oliver Sander, Peter K Cheung, Francisco S Domingues, Joachim Büch, Martin Däumer, Rolf Kaiser, Thomas Lengauer, P Richard Harrigan | Predicting HIV coreceptor usage on th... | |
| 2007 | Guangwei Yang, Ginger E Dutschman, Chuan-Jen Wang, Hiromichi Tanaka, Masanori Baba, Karen S Anderson, Yung-Chi Cheng | Highly selective action of triphospha... | |
| 2007 | Bruno Marchand, Egor P Tchesnokov, Matthias Götte | The pyrophosphate analogue foscarnet ... | RT,All properties |
| 2007 | Sanjeewa Dharmasena, Zita Pongracz, Edward Arnold, Stefan G Sarafianos, Michael A. Parniak | 3'-Azido-3'-deoxythymidine-(5')-tetra... | RT,All properties |
| 2007 | M R Loutfy, J M Raboud, J S G Montaner, T Antoniou, Brian Wynhoven, F Smaill, D Rouleau, J Gill, W Schlech, Zabrina L Brumme, Theresa Mo, K Gough, A Rachlis, P Richard Harrigan, S L Walmsley | Assay of HIV gp41 amino acid sequence... | |
| 2007 | L W Y Tam, Robert S Hogg, Benita Yip, J S G Montaner, P Richard Harrigan, Chanson J Brumme | Performance of a World Health Organiz... | |
| 2007 | Dirk Eggink, Marleen C D G Huigen, Charles A B Boucher, Matthias Götte, Monique Nijhuis | Insertions in the beta3-beta4 loop of... | |
| 2007 | Alok Mulky, B Christie Vu, Joan A Conway, Stephen H Hughes, John C Kappes | Analysis of amino acids in the beta7-... | |
| 2007 | Soo-Huey Yap, Chih-Wei Sheen, Jonathan Fahey, Mark Zanin, David Tyssen, Viviane Dias Lima, Brian Wynhoven, Michael Kuiper, Nicolas Sluis-Cremer, P Richard Harrigan, Gilda Tachedjian | N348I in the connection domain of HIV... | RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Storage requirements,RNase H,All properties |
| 2007 | Fernando A Frankel, Cédric F Invernizzi, Maureen Oliveira, Mark A. Wainberg | Diminished efficiency of HIV-1 revers... | |
| 2007 | Marshall L Morningstar, Thomas Roth, David W Farnsworth, Marilyn B Kroeger Smith, Karen M Watson, Robert W Buckheit, Kalyan Das, Weiming Zhang, Edward Arnold, John G Julias, Stephen H Hughes, Christopher J Michejda | Synthesis, biological activity, and c... | |
| 2007 | Yazan El Safadi, Valérie Vivet-Boudou, Roland Marquet | HIV-1 reverse transcriptase inhibitors. | RT,All properties |
| 2007 | Galina N Nikolenko, Krista A Delviks-Frankenberry, Sarah Palmer, Frank Maldarelli, Matthew J Fivash, John M Coffin, Vinay K Pathak | Mutations in the connection domain of... | |
| 2007 | Matthias Götte | Mechanisms of resistance associated w... | |
| 2007 | Hikaru Yamanaka, Hiroyuki Gatanaga, Pope Kosalaraksa, Saori Matsuoka-Aizawa, Tomonori Takahashi, Seisuke Kimura, Shinichi Oka | Novel mutation of human DNA polymeras... | |
| 2007 | Matthias Götte | Should we include connection domain m... | |
| 2007 | George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Matthias Gotte, Janice D Pata, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice | Investigating the "steric gate" of hu... | |
| 2007 | Kassim F Adebambo, Samantha Zanoli, Michael G Thomas, Reynel Cancio, Nicola M Howarth, Giovanni Maga | N2-benzyloxycarbonylguan-9-yl acetic ... | |
| 2007 | Reynel Cancio, Antonello Mai, Dante Rotili, Marino Artico, Gianluca Sbardella, Imma Clotet-Codina, José A Esté, Emmanuele Crespan, Samantha Zanoli, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Slow-, tight-binding HIV-1 reverse tr... | |
| 2007 | J Scott Daniels, Robert Espina, Kevin Cao, Haodan Yuan, Jianrong Lin, Sharon Diamond, Barry Johnson, James Rodgers, Shimoga Prakash, Steve Unger, David Christ, Gerald Miwa, Liang-Shang Gan, Abdul Mutlib | Species-specific, P450- and sulfotran... | |
| 2007 | Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna-Maria Monforte, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Alba Chimirri | Discovery of novel benzimidazolones a... | |
| 2007 | Giovanni Maga, Marco Radi, Samantha Zanoli, Fabrizio Manetti, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Chiara Falciani, Montserrat Terrazas, Jaume Vilarrasa, Maurizio Botta | Discovery of non-nucleoside inhibitor... | |
| 2007 | Wei-Hao Liao, Kuo-Jung Huang, Yu-Fen Chang, Shiu-Mei Wang, Ying-Tzu Tseng, Chien-Cheng Chiang, Jaang-Jiun Wang, Chin-Tien Wang | Incorporation of human immunodeficien... | |
| 2007 | Naoko Iwata, Hiroaki Yoshida, Minoru Tobiume, Fumiko Ono, Takuya Shimazaki, Tetsutaro Sata, Noriko Nakajima | Simian fetal brain progenitor cells f... | |
| 2007 | Michael G Thomas, Giovanni Maga, Jean-François Mouscadet, Nicola M Howarth | Investigation of novel lipid-function... | |
| 2007 | Giuseppe La Regina, Antonio Coluccia, Francesco Piscitelli, Alberto Bergamini, Anna Sinistro, Antonella Cavazza, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Ettore Novellino, Marino Artico, Romano Silvestri | Indolyl aryl sulfones as HIV-1 non-nu... | |
| 2007 | Stefania Paolucci, Fausto Baldanti, Giulia Campanini, Reynel Cancio, Amalia Belfiore, Giovanni Maga, Giuseppe Gerna | NNRTI-selected mutations at codon 190... | |
| 2007 | Zhengqiang Wang, Eric M Bennett, Daniel J Wilson, Christine E Salomon, Robert Vince | Rationally designed dual inhibitors o... | |
| 2007 | Jianbin Wang, H X Wang, T B Ng | A peptide with HIV-1 reverse transcri... | |
| 2007 | Jianing Wang, Yunho Jin, Kimberly L Rapp, Raymond F Schinazi, Chung K Chu | D- and L-2',3'-didehydro-2',3'-dideox... | |
| 2007 | Dirk Daelemans, Richard Lu, Erik De Clercq, Alan Engelman | Characterization of a replication-com... | |
| 2007 | Sonia de Castro, Graziela Andrei, Robert Snoeck, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez | Novel non-nucleoside human cytomegalo... | |
| 2007 | Jan Balzarini, Barbara Orzeszko, Jan K Maurin, Andrzej Orzeszko | Synthesis and anti-HIV studies of 2-a... | |
| 2007 | Erik De Clercq | Anti-HIV drugs. | |
| 2007 | Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Synthesis and evaluation of 2-(2,6-di... | |
| 2007 | Lei Ji, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV-1 activity eva... | |
| 2007 | Fernando A Frankel, Dimitrios Coutsinos, Hongtao Xu, Mark A. Wainberg | Kinetics of inhibition of HIV type 1 ... | |
| 2007 | Lingjie Liao, Hui Xing, Xincang Li, Yuhua Ruan, Yongqing Zhang, Guangming Qin, Yiming Shao | Genotypic analysis of the protease an... | |
| 2007 | Tokumi Maruyama, Yosuke Demizu, Shigetada Kozai, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq | Antiviral activity of 3-(3,5-dimethyl... | |
| 2007 | Lei Ji, Fen-Er Chen, Bin Xie, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV activity evalu... | |
| 2007 | Jingde Wu, Xinyong Liu, Xianchao Cheng, Yuan Cao, Defeng Wang, Zhongjie Li, Wenfang Xu, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq | Synthesis of novel derivatives of 4-a... | |
| 2007 | Ravindra K Rawal, Raj Kamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Synthesis and biological evaluation o... | |
| 2007 | Scott J Garforth, Tae Woo Kim, Michael A. Parniak, Eric T Kool, Vinayaka R Prasad | Site-directed mutagenesis in the fing... | |
| 2007 | Kristel Van Laethem, Christophe Pannecouque, Anne-Mieke Vandamme | Mutations at 65 and 70 within the con... | |
| 2007 | Matthew D Cullen, Bo-Liang Deng, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis and biological evaluation o... | |
| 2006 | Hiroshi Ohrui, Satoru Kohgo, Hiroyuki Hayakawa, Eiichi N Kodama, Masao Matsuoka, Tomohiro Nakata, Hiroyuki Mitsuya | 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosi... | RT,All properties |
| 2006 | Roberto Di Santo, Roberta Costi, Marino Artico, Rino Ragno, Antonio Lavecchia, Ettore Novellino, Enrico Gavuzzo, Francesco La Torre, Roberto Cirilli, Reynel Cancio, Giovanni Maga | Design, synthesis, biological evaluat... | |
| 2006 | Matthias Götte | Effects of nucleotides and nucleotide... | RT,All properties |
| 2006 | Dirk Jochmans, Jérôme Deval, Bart Kesteleyn, Herwig Van Marck, Eva Bettens, Inky De Baere, Pascale Dehertogh, Tania Ivens, Marcia Van Ginderen, Bertrand Van Schoubroeck, Maryam Ehteshami, Piet Wigerinck, Matthias Götte, Kurt Hertogs | Indolopyridones inhibit human immunod... | RT,All properties |
| 2006 | Najim A Al-Masoudi, Yaseen A Al-Soud, Aris Kalogerakis, Christophe Pannecouque, Erik De Clercq | Nitroimidazoles, part 2: Synthesis, a... | |
| 2006 | Zandrea Ambrose, John G Julias, Paul L Boyer, Vineet N Kewalramani, Stephen H Hughes | The level of reverse transcriptase (R... | |
| 2006 | Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong | Novel nonnucleoside inhibitors that s... | |
| 2006 | Klaus Klumpp, Tara Mirzadegan | Recent progress in the design of smal... | |
| 2006 | Paul L Boyer, Stefan G Sarafianos, Patrick K Clark, Edward Arnold, Stephen H Hughes | Why do HIV-1 and HIV-2 use different ... | |
| 2006 | Christine E Koval, Carrie Dykes, Jiong Wang, Lisa M Demeter | Relative replication fitness of efavi... | |
| 2006 | Jiong Wang, Carrie Dykes, R A Domaoal, Christine E Koval, R A Bambara, Lisa M Demeter | The HIV-1 reverse transcriptase mutan... | |
| 2006 | Carrie Dykes, Jiong Wang, Xia Jin, Vicente Planelles, Dong Sung An, Amanda Tallo, Yangxin Huang, Hulin Wu, Lisa M Demeter | Evaluation of a multiple-cycle, recom... | |
| 2006 | Sarit Aviel-Ronen, Chang Qi Zhu, Bradley P Coe, Ni Liu, Spencer K Watson, Wan L Lam, Ming Sound Tsao | Large fragment Bst DNA polymerase for... | |
| 2006 | Monica E Hamburgh, Kenneth A Curr, Melissa Monaghan, Vasudev R Rao, Snehlata Tripathi, Bradley D Preston, Stefan G Sarafianos, Edward Arnold, Thomas Darden, Vinayaka R Prasad | Structural determinants of slippage-m... | |
| 2006 | Valentina Svicher, Tobias Sing, Maria Mercedes Santoro, Federica Forbici, Fátima Rodríguez-Barrios, Ada Bertoli, Niko Beerenwinkel, Maria Concetta Bellocchi, Federigo Gago, Antonella d'Arminio Monforte, Andrea Antinori, Thomas Lengauer, F Ceccherini-Silberstein, CF Perno | Involvement of novel human immunodefi... | |
| 2006 | Lei Ji, Fen-Er Chen, Xiao-Qing Feng, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2006 | Frank Goebel, Alexy Yakovlev, Anton L Pozniak, Elena Vinogradova, Griet Boogaerts, Richard Hoetelmans, Marie-Pierre P De Béthune, Monika Peeters, Brian Woodfall | Short-term antiviral activity of TMC2... | |
| 2006 | Varuni K Jamburuthugoda, Pauline Chugh, Baek Kim | Modification of human immunodeficienc... | |
| 2006 | Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Combining mutations in HIV-1 reverse ... | |
| 2006 | Gabriella De Martino, Giuseppe La Regina, Rino Ragno, Antonio Coluccia, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri | Indolyl aryl sulphones as HIV-1 non-n... | |
| 2006 | Nicolas Sluis-Cremer, Noureddine Hamamouch, Ana San Félix, Sonsoles Velazquez, Jan Balzarini, María-José Camarasa | Structure-activity relationships of [... | |
| 2006 | Kirsten L White, James M Chen, Joy Y Feng, Nicolas A Margot, John K Ly, Adrian S Ray, Holly L Macarthur, Martin J McDermott, S Swaminathan, Michael D Miller | The K65R reverse transcriptase mutati... | |
| 2006 | Antonio Lavecchia, Roberta Costi, Marino Artico, Gaetano Miele, Ettore Novellino, Alberto Bergamini, Emmanuele Crespan, Giovanni Maga, Roberto Di Santo | Arylthiopyrrole (AThP) derivatives as... | |
| 2006 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, María-Cruz Bonache, Sonia de Castro | TSAO derivatives, inhibitors of HIV-1... | |
| 2006 | Daniel M Himmel, Stefan G Sarafianos, Sanjeewa Dharmasena, Mohammed M Hossain, Kessler McCoy-Simandle, Tatiana Ilina, Arthur D Clark, Jennifer L Knight, John G Julias, Patrick K Clark, Karsten Krogh-Jespersen, Ronald M Levy, Stephen H Hughes, Michael A. Parniak, Edward Arnold | HIV-1 reverse transcriptase structure... | RT,RNase H,All properties |
| 2006 | Bo-Liang Deng, Matthew D Cullen, Zhigang Zhou, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman | Synthesis and anti-HIV activity of ne... | |
| 2006 | Carlos Cruchaga, Elena Ansó, Ana Rouzaut, Juan J Martínez-Irujo | Selective excision of chain-terminati... | |
| 2006 | Tokumi Maruyama, Shigetada Kozai, Yosuke Demizu, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq | Synthesis and anti-HIV-1 and anti-HCM... | |
| 2006 | CF Perno, Valentina Svicher, Dominique Schols, Michela Pollicita, Jan Balzarini, Stefano Aquaro | Therapeutic strategies towards HIV-1 ... | |
| 2006 | Enzo Tramontano | HIV-1 RNase H: recent progress in an ... | |
| 2006 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, Federico Gago | Dimerization inhibitors of HIV-1 reve... | |
| 2006 | N Machouf, R Thomas, V K Nguyen, B Trottier, M R Boulassel, Mark A. Wainberg, Jean-Pierre Routy | Effects of drug resistance on viral l... | |
| 2006 | Jingshan Ren, Charles E Nichols, Anna Stamp, Phillip P Chamberlain, Robert G Ferris, Kurt L Weaver, Steven A Short, David K Stammers | Structural insights into mechanisms o... | |
| 2006 | Roberto Di Santo, Roberta Costi, Marino Artico, Gaetano Miele, Antonio Lavecchia, Ettore Novellino, Alberto Bergamini, Reynel Cancio, Giovanni Maga | Arylthiopyrrole (AThP) derivatives as... | |
| 2005 | Joël Didierjean, Catherine Isel, Flore Querré, Jean-François Mouscadet, Anne-Marie Aubertin, Jean-Yves Valnot, Serge R Piettre, Roland Marquet | Inhibition of human immunodeficiency ... | |
| 2005 | Hong Li, Zhengqiang Wang, Wei-guo Cui, Yan Liang, Tian-yi Xin, Jinming Li | [Study on adherence and interrelated ... | |
| 2005 | Tongfei Wu, Matheus Froeyen, Veerle Kempeneers, Christophe Pannecouque, Jing Wang, Roger Busson, Erik De Clercq, Piet Herdewijn | Deoxythreosyl phosphonate nucleosides... | |
| 2005 | Guang-Fu Sun, Xu-Xiang Chen, Fen-Er Chen, Yue-Ping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse-transcrip... | |
| 2005 | Joeri Auwerx, Joke Van Nieuwenhove, Fátima Rodríguez-Barrios, Sonia de Castro, Sonsoles Velázquez, F Ceccherini-Silberstein, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini | The N137 and P140 amino acids in the ... | |
| 2005 | Yaofeng Zhao, Yang Jin, Jing-Houng Wang, Rui-Rui Wang, Liu-Meng Yang, Wen-Hui Lee, Yong-Tang Zheng, Yongqing Zhang | A novel heme-containing protein with ... | |
| 2005 | Daniel M Himmel, Kalyan Das, Arthur D Clark, Stephen H Hughes, Abdellah Benjahad, Said Oumouch, Jérôme Guillemont, Sophie Coupa, Alain Poncelet, Imre Csoka, Christophe Meyer, Koen Andries, Chi Hung Nguyen, David S Grierson, Edward Arnold | Crystal structures for HIV-1 reverse ... | RT,Associated condition,All properties |
| 2005 | Junmei Wang, Xinshan Kang, Irwin D Kuntz, Peter A Kollman | Hierarchical database screenings for ... | |
| 2005 | Hong Zang, Thomas M Harris, F Peter Guengerich | Kinetics of nucleotide incorporation ... | |
| 2005 | Jan Balzarini, Joeri Auwerx, Fátima Rodríguez-Barrios, Allel Chedad, Viktor Farkas, F Ceccherini-Silberstein, Carlos García-Aparicio, Sonsoles Velázquez, Erik De Clercq, CF Perno, María-José Camarasa, Federico Gago | The amino acid Asn136 in HIV-1 revers... | |
| 2005 | Jan Balzarini, Kristel Van Laethem, Sigrid Hatse, Matheus Froeyen, Els Van Damme, Anders Bolmstedt, Willy Peumans, Erik De Clercq, Dominique Schols | Marked depletion of glycosylation sit... | |
| 2005 | Hong Zang, Thomas M Harris, F Peter Guengerich | Kinetics of nucleotide incorporation ... | |
| 2005 | Myriam Witvrouw, Valery Fikkert, Anke Hantson, Christophe Pannecouque, Barry R O'keefe, James McMahon, Leonidas Stamatatos, Erik De Clercq, Anders Bolmstedt | Resistance of human immunodeficiency ... | |
| 2005 | Caterina Fattorusso, Sandra Gemma, Stefania Butini, Paul Huleatt, Bruno Catalanotti, Marco Persico, Meri De Angelis, Isabella Fiorini, Vito Nacci, Anna Ramunno, Manuela Rodriquez, Giovanni Greco, Ettore Novellino, Alberto Bergamini, Stefano Marini, Massimo Coletta, Giovanni Maga, Silvio Spadari, Giuseppe Campiani | Specific targeting highly conserved r... | |
| 2005 | Fátima Rodríguez-Barrios, Jan Balzarini, Federico Gago | The molecular basis of resilience to ... | |
| 2005 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez | TSAO derivatives the first non-peptid... | |
| 2005 | Joeri Auwerx, Fátima Rodríguez-Barrios, F Ceccherini-Silberstein, Ana San-Félix, Sonsoles Velázquez, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini | The role of Thr139 in the human immun... | |
| 2005 | Albert Nguyen Van Nhien, Cyrille Tomassi, Christophe Len, José Luis Marco-Contelles, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Denis Postel | First synthesis and evaluation of the... | |
| 2005 | Guang-Fu Sun, Yun-Yan Kuang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Non-nucleoside HIV reverse transcript... | |
| 2005 | Micha Nethe, Ben Berkhout, Antoinette C van der Kuyl | Retroviral superinfection resistance. | |
| 2005 | Ronald B Geskus, Laurence Meyer, Jean-Baptiste Hubert, Hanneke Schuitemaker, Ben Berkhout, Christine Rouzioux, Ioannis D Theodorou, Jean-François Delfraissy, Maria Prins, Roel A Coutinho | Causal pathways of the effects of age... | |
| 2005 | Ben Berkhout, Anthony de Ronde, Lia van der Hoek | Aggressive HIV-1? | |
| 2005 | Jan Heeres, Marc R De Jonge, Lucien M H Koymans, Frits F D Daeyaert, Maarten H Vinkers, Koen J A Van Aken, Edward Arnold, Kalyan Das, Amuri Kilonda, Georges J Hoornaert, Frans Compernolle, Marek Cegla, Rasha A Azzam, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Paul A J Janssen | Design, synthesis, and SAR of a novel... | |
| 2005 | Scott R Budihas, Inna Gorshkova, Sergei A Gaidamakov, Antony Wamiru, Marion K Bona, Michael A. Parniak, Robert J Crouch, James B McMahon, John A Beutler, Stuart F J Le Grice | Selective inhibition of HIV-1 reverse... | |
| 2005 | Pia S Kivelä, Anneke Krol, Mika O Salminen, Ronald B Geskus, Jukka I Suni, Veli-Jukka Anttila, Kirsi Liitsola, Veera Zetterberg, Frank Miedema, Ben Berkhout, Roel A Coutinho, Matti A Ristola | High plasma HIV load in the CRF01-AE ... | |
| 2005 | Lia van der Hoek, Nicole Back, Maarten F Jebbink, Anthony de Ronde, Margreet Bakker, Suzanne Jurriaans, Peter Reiss, Neil Parkin, Ben Berkhout | Increased multinucleoside drug resist... | |
| 2005 | Ariel Roldan, Otis U Warren, Rodney S Russell, Chen Liang, Mark A. Wainberg | A HIV-1 minimal gag protein is superi... | |
| 2005 | Jan Balzarini, Miguel Stevens, Erik De Clercq, Dominique Schols, Christophe Pannecouque | Pyridine N-oxide derivatives: unusual... | |
| 2005 | Natalia A Lebedeva, T A Seredina, V N Silnikov, T V Abramova, A S Levina, Svetlana N Khodyreva, Nadejda I Rechkunova, Olga I Lavrik | Analysis of interactions of DNA polym... | |
| 2005 | Cathryn A Shaw-Reid, Bradley Feuston, Vandna Munshi, Krista Getty, Julie Krueger, Daria J Hazuda, Michael A. Parniak, Michael D Miller, Dale Lewis | Dissecting the effects of DNA polymer... | |
| 2005 | Emmanuele Crespan, Samantha Zanoli, Anastasiya Khandazhinskaya, Igor V Shevelev, Maxim Jasko, Ludmila Alexandrova, Marina Kukhanova, Giuseppina Blanca, Giuseppe Villani, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Incorporation of non-nucleoside triph... | |
| 2005 | Luis R Miranda, Matthias Götte, Fei Liang, Daniel R Kuritzkes | The L74V mutation in human immunodefi... | |
| 2005 | Darwin J Operario, Holly M Reynolds, Baek Kim | Comparison of DNA polymerase activiti... | Molecular Weight,Overall Error Rate,All properties |
| 2005 | Melaku Adal, Workenesh Ayele, Dawit Wolday, Kifle Dagne, Tsehaynesh Messele, Tesfaye Tilahun, Ben Berkhout, Shlomo Mayaan, Georgios Pollakis, Wendelien Dorigo-Zetsma | Evidence of genetic variability of hu... | |
| 2005 | Kalyan Das, Paul J Lewi, Stephen H Hughes, Edward Arnold | Crystallography and the design of ant... | |
| 2005 | Abdellah Benjahad, Martine Croisy, Claude Monneret, Emile Bisagni, Dominique Mabire, Sophie Coupa, Alain Poncelet, Imre Csoka, Jérôme Guillemont, Christophe Meyer, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Daniel M Himmel, Kalyan Das, Edward Arnold, Chi Hung Nguyen, David S Grierson | 4-Benzyl and 4-benzoyl-3-dimethylamin... | |
| 2005 | Fernando A Frankel, Bruno Marchand, Dan Turner, Matthias Götte, Mark A. Wainberg | Impaired rescue of chain-terminated D... | |
| 2005 | Michael E Ignatov, Anthony J Berdis, Stuart F J Le Grice, Mary D Barkley | Attenuation of DNA replication by HIV... | |
| 2005 | Erik De Clercq | Emerging anti-HIV drugs. | |
| 2005 | Mark A. Wainberg, James P C Sawyer, Julio S G Montaner, Robert L Murphy, Daniel R Kuritzkes, Francois Raffi | Challenges for the clinical developme... | |
| 2005 | Dan Turner, Bluma G Brenner, Daniela D Moisi, Chen Liang, Mark A. Wainberg | Substitutions in the Reverse Transcri... | |
| 2005 | Dan Turner, Bluma G Brenner, Daniela Mosis, Chen Liang, Mark A. Wainberg | Substitutions in the reverse transcri... | |
| 2005 | Gabriella De Martino, Giuseppe La Regina, Alessandra Di Pasquali, Rino Ragno, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri | Novel 1-[2-(diarylmethoxy)ethyl]-2-me... | |
| 2005 | Bo-Liang Deng, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman | Synthesis, anti-HIV activity, and met... | |
| 2005 | Nicolas Sluis-Cremer, Dominique Arion, Urvi Parikh, Dianna Koontz, Raymond F Schinazi, John W Mellors, Michael A. Parniak | The 3'-azido group is not the primary... | |
| 2005 | Paul A J Janssen, Paul J Lewi, Edward Arnold, Frits F D Daeyaert, Marc R De Jonge, Jan Heeres, Luc Koymans, Maarten H Vinkers, Jérôme Guillemont, Elisabeth Pasquier, Michael Kukla, Don Ludovici, Koen Andries, Marie-Pierre P De Béthune, Rudi Pauwels, Kalyan Das, Arthur D Clark, Yulia Volovik Frenkel, Stephen H Hughes, Bart Medaer, Fons De Knaep, Hilde Bohets, Fred De Clerck, Ann Lampo, Peter Williams, Paul Stoffels | In search of a novel anti-HIV drug: m... | |
| 2005 | Rienk E Jeeninga, Barbara Jan, Birgit van der Linden, Henk van den Berg, Ben Berkhout | Construction of a minimal HIV-1 varia... | |
| 2005 | Antonello Mai, Marino Artico, Rino Ragno, Gianluca Sbardella, Silvio Massa, Chiara Musiu, Massimo Mura, Flavia Marturana, Alessandra Cadeddu, Giovanni Maga, Paolo La Colla | 5-Alkyl-2-alkylamino-6-(2,6-difluorop... | |
| 2005 | Emmanuele Crespan, Giada A Locatelli, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Drug resistance mutations in the nucl... | |
| 2005 | Johan Vingerhoets, Hilde Azijn, Els Fransen, Inky De Baere, Liesbet Smeulders, Dirk Jochmans, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune | TMC125 displays a high genetic barrie... | |
| 2005 | Daniel Summerer, Andreas Marx | 4'C-ethynyl-thymidine acts as a chain... | |
| 2005 | Kirsten L White, Nicolas A Margot, John K Ly, James M Chen, Adrian S Ray, Martina Pavelko, Ruth Wang, Martin J McDermott, S Swaminathan, Michael D Miller | A combination of decreased NRTI incor... | |
| 2005 | Andrew R Zolopa, Laura C Lazzeroni, Alex Rinehart, Françoise Brun Vezinet, François Clavel, Ann Collier, Brian Conway, Roy M Gulick, Mark Holodniy, CF Perno, Robert W Shafer, Douglas D Richman, Mark A. Wainberg, Daniel R Kuritzkes | Accuracy, precision, and consistency ... | |
| 2005 | F Ceccherini-Silberstein, Federico Gago, Maria Mercedes Santoro, Caterina Gori, Valentina Svicher, Fátima Rodríguez-Barrios, Roberta d'Arrigo, Massimo Ciccozzi, Ada Bertoli, Antonella d'Arminio Monforte, Jan Balzarini, Andrea Antinori, CF Perno | High sequence conservation of human i... | |
| 2005 | Alok Mulky, Stefan G Sarafianos, Yujiang Jia, Edward Arnold, John C Kappes | Identification of amino acid residues... | |
| 2005 | Michael E Abram, Michael A. Parniak | Virion instability of human immunodef... | |
| 2005 | Ariel Fernández, Dan S Tawfik, Ben Berkhout, Rogier W Sanders, Andrzej Kloczkowski, Taner Sen, Bob Jernigan | Protein promiscuity: drug resistance ... | |
| 2004 | Rachelle J Bienstock, Willliam C Copeland | Molecular insights into NRTI inhibiti... | |
| 2004 | Myriam Witvrouw, Bénédicte Van Maele, J Vercammen, Anke Hantson, Y Engelborghs, Erik De Clercq, Christophe Pannecouque, Zeger Debyser | Novel inhibitors of HIV-1 integration. | |
| 2004 | Kirsten L White, James M Chen, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Lisa K Naeger, S Swaminathan, Michael D Miller | Molecular mechanisms of tenofovir res... | |
| 2004 | Maximilian A Silvestri, Muthukaman Nagarajan, Erik De Clercq, Christophe Pannecouque, Mark Cushman | Design, synthesis, anti-HIV activitie... | |
| 2004 | Maqbool A Siddiqui, Stephen H Hughes, Paul L Boyer, Hiroyuki Mitsuya, Que N Van, Clifford George, Stefan G Sarafinanos, Victor E Marquez | A 4'-C-ethynyl-2',3'-dideoxynucleosid... | |
| 2004 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Effects of mutations in the G tract o... | |
| 2004 | Stefan G Sarafianos, Stephen H Hughes, Edward Arnold | Designing anti-AIDS drugs targeting t... | |
| 2004 | Stefan G Sarafianos, Kalyan Das, Stephen H Hughes, Edward Arnold | Taking aim at a moving target: design... | |
| 2004 | Louise Z Wang, George L Kenyon, Kenneth A Johnson | Novel mechanism of inhibition of HIV-... | |
| 2004 | Alok Mulky, Stefan G Sarafianos, Edward Arnold, Xiaoming Wu, John C Kappes | Subunit-specific analysis of the huma... | |
| 2004 | Bruno Marchand, Matthias Götte | Impact of the translocational equilib... | |
| 2004 | Kalyan Das, Arthur D Clark, Paul J Lewi, Jan Heeres, Marc R De Jonge, Lucien M H Koymans, H Maarten Vinkers, Frederik Daeyaert, Donald W Ludovici, Michael J Kukla, Bart De Corte, Robert W Kavash, Chih Y Ho, Hong Ye, Mark A Lichtenstein, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Paul L Boyer, Patrick K Clark, Stephen H Hughes, Paul A J Janssen, Edward Arnold | Roles of conformational and positiona... | |
| 2004 | Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà | Synthesis of new 2,3-diaryl-1,3-thiaz... | |
| 2004 | María-José Camarasa, Ana San-Félix, Sonsoles Velázquez, María-Jesús Pérez-Pérez, Federico Gago, Jan Balzarini | TSAO compounds: the comprehensive sto... | |
| 2004 | CF Perno, Emanuela Balestra, M Francesconi, D Abdelahad, Raffaele Caliò, Jan Balzarini, Stefano Aquaro | Antiviral profile of HIV inhibitors i... | |
| 2004 | Paul L Boyer, Tomozumi Imamichi, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Effects of the Delta67 complex of mut... | |
| 2004 | Koen Andries, Hilde Azijn, Theo Thielemans, Donald W Ludovici, Michael Kukla, Jan Heeres, Paul A J Janssen, Bart De Corte, Johan Vingerhoets, Rudi Pauwels, Marie-Pierre P De Béthune | TMC125, a novel next-generation nonnu... | RT,Associated condition,All properties |
| 2004 | Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Marco Petrella, Mark A. Wainberg | Rationale for maintenance of the M184... | |
| 2004 | Nicolas Sluis-Cremer, Dominique Arion, Michael E Abram, Michael A. Parniak | Proteolytic processing of an HIV-1 po... | |
| 2004 | King C Chan, Scott R Budihas, Stuart F J Le Grice, Michael A. Parniak, Robert J Crouch, Sergei A Gaidamakov, Haleem J Isaaq, Antony Wamiru, James B McMahon, John A Beutler | A capillary electrophoretic assay for... | |
| 2004 | Jan Balzarini | Current status of the non-nucleoside ... | |
| 2004 | Erik De Clercq | Antiviral drugs in current clinical use. | |
| 2004 | Joeri Auwerx, Robert Esnouf, Erik De Clercq, Jan Balzarini | Susceptibility of feline immunodefici... | |
| 2004 | Yanping He, Fener Chen, Guangfu Sun, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | 5-Alkyl-2-[(aryl and alkyloxylcarbony... | |
| 2004 | Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna-Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà | 2-(2,6-Dihalophenyl)-3-(pyrimidin-2-y... | |
| 2004 | Yanping He, Fener Chen, Xiongjie Yu, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse transcrip... | |
| 2004 | Florence Doualla-Bell, Simane Gaseitsiwe, Thumbi Ndungú, Musetsanagepe Modukanele, Trevor Peter, Vladimir Novitsky, Ndwapi Ndwapi, Gaolathe Tendani, Ava Avalos, William Wester, Hermann Bussmann, Peter Cardiello, Richard G Marlink, Howard Moffat, Ibou Thior, Mark A. Wainberg, Max Essex | Mutations and polymorphisms associate... | |
| 2004 | Mark A. Wainberg | The impact of the M184V substitution ... | |
| 2004 | Dan Turner, Ariel Roldan, Bluma G Brenner, Daniela D Moisi, Jean-Pierre Routy, Mark A. Wainberg | Variability in the PR and RT genes of... | |
| 2004 | Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Zeev Rosberger, Michel Roger, Mark A. Wainberg | Diminished representation of HIV-1 va... | |
| 2004 | Joy Y Feng, Eisuke Murakami, Suzana M Zorca, Allison A Johnson, Kenneth A Johnson, Raymond F Schinazi, Phillip A Furman, Karen S Anderson | Relationship between antiviral activi... | |
| 2004 | Eisuke Murakami, Adrian S Ray, Raymond F Schinazi, Karen S Anderson | Investigating the effects of stereoch... | |
| 2004 | Dan Turner, Bluma G Brenner, Daniela D Moisi, Mervi Detorio, Raymond Cesaire, Takashi Kurimura, Haruyo Mori, Max Essex, Shlomo Maayan, Mark A. Wainberg | Nucleotide and amino acid polymorphis... | |
| 2004 | Zandrea Ambrose, Valerie Boltz, Sarah Palmer, John M Coffin, Stephen H Hughes, Vineet N Kewalramani | In vitro characterization of a simian... | |
| 2004 | John G Julias, Paul L Boyer, Mary Jane McWilliams, W Gregory Alvord, Stephen H Hughes | Mutations at position 184 of human im... | |
| 2004 | A Michael Sismour, Stefan Lutz, Jeong-Ho Park, Michael J Lutz, Paul L Boyer, Stephen H Hughes, Steven A Benner | PCR amplification of DNA containing n... | |
| 2004 | Giada A Locatelli, Giuseppe Campiani, Reynel Cancio, Elena Morelli, Anna Ramunno, Sandra Gemma, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Effects of drug resistance mutations ... | |
| 2004 | Stefania Paolucci, Fausto Baldanti, Giovanni Maga, Reynel Cancio, Maurizio Zazzi, Maurizio Zavattoni, Antonella Chiesa, Silvio Spadari, Giuseppe Gerna | Gln145Met/Leu changes in human immuno... | |
| 2004 | Lisa F Rezende, Vinayaka R Prasad | Nucleoside-analog resistance mutation... | RT,Associated condition,All properties |
| 2004 | Jérôme Deval, Kirsten L White, Michael D Miller, Neil T Parkin, Jérôme Courcambeck, Philippe Halfon, Boulbaba Selmi, Joëlle Boretto, Bruno Canard | Mechanistic basis for reduced viral a... | |
| 2004 | Julie Qi Hang, Surendran Rajendran, Yanli Yang, Yingqian Li, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin, Klaus Klumpp | Activity of the isolated HIV RNase H ... | |
| 2004 | Kenji Kitano, Satoru Kohgo, Kohei Yamada, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui | Attempt to reduce cytotoxicity by syn... | |
| 2004 | George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Kalavathy Sitaraman, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice | Site- and subunit-specific incorporat... | |
| 2004 | Matthias Götte | Inhibition of HIV-1 reverse transcrip... | |
| 2004 | Elena N Peletskaya, Alex A Kogon, Steven Tuske, Edward Arnold, Stephen H Hughes | Nonnucleoside inhibitor binding affec... | RT,Associated condition,All properties |
| 2004 | Andrew L Hopkins, Jingshan Ren, John Milton, Richard J Hazen, Joseph H Chan, David I Stuart, David K Stammers | Design of non-nucleoside inhibitors o... | RT,Associated condition,All properties |
| 2004 | Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, David K Stammers | Crystal structures of HIV-1 reverse t... | |
| 2004 | George R Painter, Merrick R Almond, Shuli Mao, Dennis C Liotta | Biochemical and mechanistic basis for... | RT,Associated condition,All properties |
| 2004 | Jérôme Deval, Jean-Marc Navarro, Boulbaba Selmi, Jérôme Courcambeck, Joëlle Boretto, Philippe Halfon, Sarah Garrido-Urbani, Josephine Sire, Bruno Canard | A loss of viral replicative capacity ... | |
| 2004 | Dan Turner, Bluma G Brenner, Mark A. Wainberg | Relationships among various nucleosid... | |
| 2004 | Satoru Kohgo, Kohei Yamada, Kenji Kitano, Yuko Iwai, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui | Design, efficient synthesis, and anti... | |
| 2004 | Joeri Auwerx, Miguel Stevens, An R Van Rompay, Louise E Bird, Jingshan Ren, Erik De Clercq, Bo Oberg, David K Stammers, Anna Karlsson, Jan Balzarini | The phenylmethylthiazolylthiourea non... | |
| 2004 | Steve Tuske, Stefan G Sarafianos, Arthur D Clark, Jianping Ding, Lisa K Naeger, Kirsten L White, Michael D Miller, Craig S Gibbs, Paul L Boyer, Patrick K Clark, Gang Wang, Barbara L Gaffney, Roger A Jones, Donald M Jerina, Stephen H Hughes, Edward Arnold | Structures of HIV-1 RT-DNA complexes ... | |
| 2004 | Jeong-Yun Choi, F Peter Guengerich | Analysis of the effect of bulk at N2-... | |
| 2004 | Esther W Hou, Rajendra Prasad, William A Beard, Samuel H Wilson | High-level expression and purificatio... | |
| 2004 | Debanu Das, Millie M Georgiadis | The crystal structure of the monomeri... | |
| 2004 | Michael B Doughty, Karam Aboudehen, Garland Anderson, Ke Li, Bob Moore, Tina Poolson | Side-chain conformational restriction... | |
| 2004 | Elisabetta Bulgheroni, Francesco Croce, Paola Citterio, Ottavia Viganò, Raffaella Visonà, Eugenio Sala, Massimo Galli, Stefano Rusconi | Unusual codon 69 insertions: influenc... | |
| 2004 | Claudia M D'Abramo, Luciano Cellai, Matthias Götte | Excision of incorporated nucleotide a... | |
| 2004 | Giada A Locatelli, Reynel Cancio, Silvio Spadari, Giovanni Maga | HIV-1 reverse transcriptase inhibitor... | |
| 2004 | Reynel Cancio, Silvio Spadari, Giovanni Maga | Vif is an auxiliary factor of the HIV... | |
| 2004 | Erik De Clercq | Non-nucleoside reverse transcriptase ... | |
| 2004 | Peter R Meyer, Anthony J Smith, Suzanne E Matsuura, Walter A Scott | Effects of primer-template sequence o... | |
| 2004 | Paul J Lewi, Edward Arnold, Koen Andries, Hilde Bohets, Herman Borghys, Arthur D Clark, Frits F D Daeyaert, Kalyan Das, Marie-Pierre P De Béthune, Marc R De Jonge, Jan Heeres, Luc Koymans, Jos Leempoels, Jef Peeters, Philip Timmerman, Walter Van den Broeck, Frédéric Vanhoutte, Gerben Van't Klooster, Maarten H Vinkers, Yulia Volovik, Paul A J Janssen | Correlations between factors determin... | |
| 2004 | George A Freeman, C Webster Andrews Iii, Andrew L Hopkins, Gina S Lowell, Lee T Schaller, Jill R Cowan, Stephen S Gonzales, George W Koszalka, Richard J Hazen, Lawrence R Boone, Rob G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, David J Reynolds, John Milton, Jingshan Ren, David I Stuart, David K Stammers, Joseph H Chan | Design of non-nucleoside inhibitors o... | RT,Associated condition,All properties |
| 2003 | Adrian S Ray, Raymond F Schinazi, Eisuke Murakami, Aravind Basavapathruni, Junxing Shi, Suzana M Zorca, Chung K Chu, Karen S Anderson | Probing the mechanistic consequences ... | RT,Associated condition,All properties |
| 2003 | Boulbaba Selmi, Jerome Deval, Karine Alvarez, Joelle Boretto, Simon Sarfati, Catherine Guerreiro, Bruno Canard | The Y181C substitution in 3'-azido-3'... | |
| 2003 | Qian Zhao, Hong Lu, Dominique Schols, Erik De Clercq, Shibo Jiang | Development of a cell-based enzyme-li... | |
| 2003 | Karidia Diallo, Bruno Marchand, Xin Wei, Luciano Cellai, Matthias Götte, Mark A. Wainberg | Diminished RNA primer usage associate... | |
| 2003 | Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg | Negative effect of the M184V mutation... | |
| 2003 | Giuseppina Blanca, Igor V Shevelev, Kristijan Ramadan, Giuseppe Villani, Silvio Spadari, Ulrich Hübscher, Giovanni Maga | Human DNA polymerase lambda diverged ... | |
| 2003 | Jan Balzarini, Erik De Clercq, Beata Kaminska, Andrzej Orzeszko | Synthesis and antiviral activity of s... | |
| 2003 | Stefania Paolucci, Fausto Baldanti, Marco Tinelli, Giovanni Maga, Giuseppe Gerna | Detection of a new HIV-1 reverse tran... | |
| 2003 | Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini | Inhibition of human immunodeficiency ... | |
| 2003 | Susan E Lim, Mikhail V Ponamarev, Matthew J Longley, William C Copeland | Structural determinants in human DNA ... | |
| 2003 | Peter R Meyer, Johan Lennerstrand, Suzanne E Matsuura, Brendan A Larder, Walter A Scott | Effects of dipeptide insertions betwe... | |
| 2003 | Klaus Klumpp, Julie Qi Hang, Surendran Rajendran, Yanli Yang, Andre Derosier, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin | Two-metal ion mechanism of RNA cleava... | |
| 2003 | Ge Meng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse transcrip... | |
| 2003 | Mélanie Girouard, Karidia Diallo, Bruno Marchand, Suzanne McCormick, Matthias Götte | Mutations E44D and V118I in the rever... | |
| 2003 | Nicolas Sluis-Cremer, Ellis Kempner, Michael A. Parniak | Structure-activity relationships in H... | |
| 2003 | Romas Geleziunas, Karen Gallagher, Hangchun Zhang, Lee Bacheler, Sena Garber, Jing-Tao Wu, Guoen Shi, Michael J Otto, Raymond F Schinazi, Susan Erickson-Viitanen | HIV-1 resistance profile of the novel... | |
| 2003 | Irene M Lagoja, Christophe Pannecouque, Arthur Van Aerschot, Myriam Witvrouw, Zeger Debyser, Jan Balzarini, Piet Herdewijn, Erik De Clercq | N-aminoimidazole derivatives inhibiti... | |
| 2003 | Maria Letizia Barreca, Alba Chimirri, Erik De Clercq, Laura De Luca, Anna-Maria Monforte, Pietro Monforte, Angela Rao, Maria Zappalà | Anti-HIV agents: design and discovery... | |
| 2003 | Angelo Ranise, Andrea Spallarossa, Silvia Schenone, Olga Bruno, Francesco Bondavalli, Laura Vargiu, Tiziana Marceddu, Massimo Mura, Paolo La Colla, Alessandra Pani | Design, synthesis, SAR, and molecular... | |
| 2003 | Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini | Novel human immunodeficiency virus (H... | |
| 2003 | Koyo Ariyoshi, Masakazu Matsuda, Hideka Miura, Sachiko Tateishi, Kaneo Yamada, Wataru Sugiura | Patterns of point mutations associate... | |
| 2003 | Bluma G Brenner, Dan Turner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Mauricio Carobene, Richard G Marlink, Jonathan Schapiro, Michel Roger, Mark A. Wainberg | A V106M mutation in HIV-1 clade C vir... | |
| 2003 | Karidia Diallo, Bluma G Brenner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Matthias Götte, Mark A. Wainberg | The M184V substitution in human immun... | |
| 2003 | J Gerardo García-Lerma, Hamish MacInnes, Diane Bennett, Patrick Reid, Soumya Nidtha, Hillard Weinstock, Jonathan E Kaplan, Walid Heneine | A novel genetic pathway of human immu... | |
| 2003 | Wei Huang, Andrea Gamarnik, Kay Limoli, Christos J Petropoulos, Jeannette M Whitcomb | Amino acid substitutions at position ... | |
| 2003 | Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Mutations in the 5' end of the human ... | |
| 2003 | Harold R Lee, Jeremiah Hanes, Kenneth A Johnson | Toxicity of nucleoside analogues used... | |
| 2003 | Myriam Witvrouw, Christophe Pannecouque, Valery Fikkert, Anke Hantson, Barbara Van Remoortel, Marjan Hezareh, Erik De Clercq, Stephen J Brown | Potent and selective inhibition of HI... | |
| 2003 | Eisuke Murakami, Joy Y Feng, Harold R Lee, Jeremiah Hanes, Kenneth A Johnson, Karen S Anderson | Characterization of novel reverse tra... | |
| 2003 | Marie L Coté, Mark Pflomm, Millie M Georgiadis | Staying straight with A-tracts: a DNA... | |
| 2003 | Lingling Shen, Jianhua Shen, Xiaomin Luo, Feng Cheng, Yechun Xu, Kaixian Chen, Edward Arnold, Jianping Ding, Hualiang Jiang | Steered molecular dynamics simulation... | |
| 2003 | Joel E Gallant, Peter Z Gerondelis, Mark A. Wainberg, Nancy S Shulman, Richard H Haubrich, Marty St Clair, Ernest R Lanier, Nicholas S Hellmann, Douglas D Richman | Nucleoside and nucleotide analogue re... | RT,Associated condition,All properties |
| 2003 | María-Cruz Bonache, Cristina Chamorro, Esther Lobatón, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, Ana San-Félix | Structure-activity relationship studi... | |
| 2003 | Peter R Meyer, Suzanne E Matsuura, Dianna Zonarich, Rahul R Chopra, Eric Pendarvis, Holly Z Bazmi, John W Mellors, Walter A Scott | Relationship between 3'-azido-3'-deox... | |
| 2003 | Adrian S Ray, Eisuke Murakami, Aravind Basavapathruni, Joseph A Vaccaro, Dagny Ulrich, Chung K Chu, Raymond F Schinazi, Karen S Anderson | Probing the molecular mechanisms of A... | |
| 2003 | Tokumi Maruyama, Shigetada Kozai, Tetsuo Yamasaki, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoeck, Graciella Andrei, Erik De Clercq | Synthesis and antiviral activity of 1... | |
| 2003 | Jaroslaw Poznanski, Maria Bretner, Tadeusz Kulikowski, Jan Balzarini, Arthur Van Aerschot, Erik De Clercq | Synthesis, solution conformation and ... | |
| 2003 | Michael A. Parniak, Kyung-Lyum Min, Scott R Budihas, Stuart F J Le Grice, John A Beutler | A fluorescence-based high-throughput ... | |
| 2003 | Sanjay U C Sankatsing, Gerrit J Weverling, Monika Peeters, Gerben van't Klooster, Boris Gruzdev, Aza Rakhmanova, Sven A Danner, Suzanne Jurriaans, Jan M Prins, Joep M A Lange | TMC125 exerts similar initial antivir... | |
| 2003 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Mutation of amino acids in the connec... | |
| 2003 | Giuseppina Blanca, Fausto Baldanti, Stefania Paolucci, Alexander Yu Skoblov, Lyubov Victorova, Ulrich Hübscher, Giuseppe Gerna, Silvio Spadari, Giovanni Maga | Nevirapine resistance mutation at cod... | |
| 2003 | Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, Jingshan Ren, David I Stuart, David K Stammers | Cloning, expression, purification, an... | |
| 2003 | Marilyn B Kroeger Smith, Sandra Ruby, Stanislav Horouzhenko, Bryan Buckingham, Julia Richardson, Ina Puleri, Emily Potts, William L Jorgensen, Edward Arnold, Weiming Zhang, Stephen H Hughes, Christopher J Michejda, Richard H Smith | HIV-1 reverse transcriptase variants:... | |
| 2003 | Marilyn B Kroeger Smith, Brian M Hose, Arie Hawkins, James Lipchock, David W Farnsworth, Robert C Rizzo, Julian Tirado-Rives, Edward Arnold, Weiming Zhang, Stephen H Hughes, William L Jorgensen, Christopher J Michejda, Richard H Smith | Molecular modeling calculations of HI... | |
| 2003 | Bruno Marchand, Matthias Götte | Site-specific footprinting reveals di... | |
| 2003 | William A Beard, Samuel H Wilson | Structural insights into the origins ... | |
| 2003 | Martin Stürmer, Schlomo Staszewski, Hans-Wilhelm Doerr, Brendan A Larder, Stuart Bloor, Kurt Hertogs | Correlation of phenotypic zidovudine ... | |
| 2003 | Marie-Pierre Golinelli, Stephen H Hughes | Secondary structure in the nucleic ac... | |
| 2003 | Cathryn A Shaw-Reid, Vandna Munshi, Pia Graham, Abigail Wolfe, Marc Witmer, Renee Danzeisen, David B Olsen, Steven S Carroll, Mark Embrey, John S Wai, Michael D Miller, James L Cole, Daria J Hazuda | Inhibition of HIV-1 ribonuclease H by... | |
| 2003 | Yudong Quan, Bluma G Brenner, Maureen Oliveira, Mark A. Wainberg | Lamivudine can exert a modest antivir... | |
| 2003 | Evguenia S Svarovskaia, Sara R Cheslock, Wen-Hui Zhang, Wei-Shau Hu, Vinay K Pathak | Retroviral mutation rates and reverse... | |
| 2003 | Yongseok Choi, Clifford George, Maria J Comin, Joseph J Barchi, Hak Sung Kim, Kenneth A Jacobson, Jan Balzarini, Hiroyuki Mitsuya, Paul L Boyer, Stephen H Hughes, Victor E Marquez | A conformationally locked analogue of... | |
| 2002 | Jingshan Ren, Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, David I Stuart, David K Stammers | Structure of HIV-2 reverse transcript... | |
| 2002 | Stefan G Sarafianos, Arthur D Clark, Kalyan Das, Steve Tuske, Jens J Birktoft, Palanichamy Ilankumaran, Andagar R Ramesha, Jane M Sayer, Donald M Jerina, Paul L Boyer, Stephen H Hughes, Edward Arnold | Structures of HIV-1 reverse transcrip... | |
| 2002 | Kirsten L White, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Michael D Miller, Lisa K Naeger | Molecular mechanisms of resistance to... | |
| 2002 | Dominique Arion, Nicolas Sluis-Cremer, Kyung-Lyum Min, Michael E Abram, Ronald S Fletcher, Michael A. Parniak | Mutational analysis of Tyr-501 of HIV... | |
| 2002 | Marie-Pierre Golinelli, Stephen H Hughes | Nontemplated base addition by HIV-1 R... | |
| 2002 | Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak | Destabilization of the HIV-1 reverse ... | |
| 2002 | Yoshiyuki Mizushina, Chikako Murakami, Keisuke Ohta, Hirosato Takikawa, Kenji Mori, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi | Selective inhibition of the activitie... | |
| 2002 | A Geoffrey Skillman, Karl W Maurer, Diana C Roe, Margaret J Stauber, Dolan Eargle, Todd J A Ewing, Angelika Muscate, Elisabeth Davioud-Charvet, Maxine V Medaglia, Robert J Fisher, Edward Arnold, Hong Qiang Gao, Robert W Buckheit, Paul L Boyer, Stephen H Hughes, Irwin D Kuntz, George L Kenyon | A novel mechanism for inhibition of H... | |
| 2002 | P Richard Harrigan, Mahboob Salim, David K Stammers, Brian Wynhoven, Zabrina L Brumme, Paula McKenna, Brendan A Larder, S D Kemp | A mutation in the 3' region of the hu... | |
| 2002 | Michael Strerath, Janina Cramer, Tobias Restle, Andreas Marx | Implications of active site constrain... | |
| 2002 | Marie-Pierre Golinelli, Stephen H Hughes | Nontemplated nucleotide addition by H... | |
| 2002 | Zeger Debyser, Peter Cherepanov, Bénédicte Van Maele, Erik De Clercq, Myriam Witvrouw | In search of authentic inhibitors of ... | |
| 2002 | Jason W Rausch, Daniela Lener, Jennifer T Miller, John G Julias, Stephen H Hughes, Stuart F J Le Grice | Altering the RNase H primer grip of h... | |
| 2002 | Dimitrios Motakis, Michael A. Parniak | A tight-binding mode of inhibition is... | |
| 2002 | Louis M Mansky | HIV mutagenesis and the evolution of ... | |
| 2002 | Erik De Clercq | Highlights in the development of new ... | |
| 2002 | Erik De Clercq | New anti-HIV agents and targets. | |
| 2002 | Janice D Pata, Bradford R King, Thomas A Steitz | Assembly, purification and crystalliz... | |
| 2002 | Marinela Perpelescu, Jun'ichi Kobayashi, Miho Furuta, Yasutomo Ito, Shunji Izuta, Masaharu Takemura, Motoshi Suzuki, Shonen Yoshida | Novel phenalenone derivatives from a ... | |
| 2002 | Peter R Meyer, Suzanne E Matsuura, Adviye A Tolun, Ingrid Pfeifer, Antero G So, John W Mellors, Walter A Scott | Effects of specific zidovudine resist... | |
| 2002 | N McLellan, Xin Wei, Bruno Marchand, Mark A. Wainberg, Matthias Götte | Nonradioactive detection of retrovira... | |
| 2002 | Adrienne M Woodside, F Peter Guengerich | Effect of the O6 substituent on misin... | |
| 2002 | Stefano Aquaro, Raffaele Caliò, Jan Balzarini, Maria Concetta Bellocchi, Enrico Garaci, CF Perno | Macrophages and HIV infection: therap... | |
| 2002 | R Masciari, L Cosco, M C Diaco, Dora N Della, T Ferraro, T Raimondi, B Ruperti, E Santandrea | HIV-1: a case of RT67 deletion in a m... | |
| 2002 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | The M184V mutation reduces the select... | |
| 2002 | Yven Van Herrewege, Lieve Penne, Chris Vereecken, Katrien Fransen, Guido van der Groen, Luc Kestens, Jan Balzarini, Guido Vanham | Activity of reverse transcriptase inh... | |
| 2002 | Adrienne M Woodside, F Peter Guengerich | Misincorporation and stalling at O(6)... | |
| 2002 | Nobuyuki Kasai, Yoshiyuki Mizushina, Fumio Sugawara, Kengo Sakaguchi | Three-dimensional structural model an... | |
| 2002 | Esther Lobatón, Fátima Rodríguez-Barrios, Federico Gago, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez | Synthesis of 3' '-substituted TSAO de... | |
| 2002 | Robert L Lobato, Eun-Young Kim, Ronald M Kagan, Thomas C Merigan | Genotypic and phenotypic analysis of ... | |
| 2002 | Koen K A Van Rompay, Tim B Matthews, Joanne Higgins, Don R Canfield, Ross P Tarara, Mark A. Wainberg, Raymond F Schinazi, Niels C Pedersen, Thomas W North | Virulence and reduced fitness of simi... | |
| 2002 | Joeri Auwerx, Thomas W North, Bradley D Preston, George J Klarmann, Erik De Clercq, Jan Balzarini | Chimeric human immunodeficiency virus... | |
| 2002 | L Menéndez-Arias | Molecular basis of fidelity of DNA sy... | |
| 2002 | Fabienne Brulé, Roland Marquet, Liwei Rong, Mark A. Wainberg, Bernard P Roques, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann | Structural and functional properties ... | |
| 2002 | Christopher J Hollowood, Steven V Ley, Shigeo Yamanoi | Synthesis of taurospongin A: a potent... | |
| 2002 | Giuseppe Campiani, Anna Ramunno, Giovanni Maga, Vito Nacci, Caterina Fattorusso, Bruno Catalanotti, Elena Morelli, Ettore Novellino | Non-nucleoside HIV-1 reverse transcri... | |
| 2002 | Bluma G Brenner, Dan Turner, Mark A. Wainberg | HIV-1 drug resistance: can we overcome? | |
| 2002 | Jimmy Lindberg, Snaevar Sigurdsson, Seved Löwgren, Hans O Andersson, Christer Sahlberg, Rolf Noréen, Kerstin Fridborg, Haijiang Zhang, Torsten Unge | Structural basis for the inhibitory e... | |
| 2002 | Karen S Anderson | Perspectives on the molecular mechani... | RT,Associated condition,All properties |
| 2002 | Phillip P Chamberlain, Jingshan Ren, Charles E Nichols, L Douglas, Johan Lennerstrand, Brendan A Larder, David I Stuart, David K Stammers | Crystal structures of Zidovudine- or ... | |
| 2002 | Mickael Rigourd, Chantal Ehresmann, Michael A. Parniak, Bernard Ehresmann, Roland Marquet | Primer unblocking and rescue of DNA s... | |
| 2002 | Timothy S Fisher, Vinayaka R Prasad | Substitutions of Phe61 located in the... | RT,Associated condition,All properties |
| 2002 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Mutations in the RNase H domain of HI... | |
| 2002 | Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg | Co-receptor usage and HIV-1 intra-cla... | |
| 2002 | Giovanni Maga, Silvio Spadari | Combinations against combinations: as... | |
| 2002 | Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg | The M184V mutation in HIV-1 reverse t... | |
| 2002 | Antonio Mas, Blanca M Vázquez-Alvarez, Esteban Domingo, L Menéndez-Arias | Multidrug-resistant HIV-1 reverse tra... | |
| 2002 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Nucleoside analog resistance caused b... | |
| 2002 | Wim Pluymers, Godwin Pais, Bénédicte Van Maele, Christophe Pannecouque, Valery Fikkert, Terrence R Burke, Erik De Clercq, Myriam Witvrouw, Nouri Neamati, Zeger Debyser | Inhibition of human immunodeficiency ... | |
| 2002 | Christophe Pannecouque, Wim Pluymers, Bénédicte Van Maele, Victor Tetz, Peter Cherepanov, Erik De Clercq, Myriam Witvrouw, Zeger Debyser | New class of HIV integrase inhibitors... | |
| 2002 | Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg | Polymorphisms of cytotoxic T-lymphocy... | |
| 2002 | Lisa K Naeger, Nicolas A Margot, Michael D Miller | ATP-dependent removal of nucleoside r... | |
| 2002 | Laurent Andréoletti, Laurence Weiss, Ali Si-Mohamed, Christophe Piketty, Thierry Prazuck, Gérard Calamy, Jean-Elie Malkin, Mathieu Matta, François-Xavier Mbopi-Kéou, François Clavel, Michel D Kazatchkine, Laurent Bélec | Multidrug-resistant HIV-1 RNA and pro... | |
| 2002 | Qingli Shi, Kamalendra Singh, Aashish Srivastava, Neerja Kaushik, Mukund J Modak | Lysine 152 of MuLV reverse transcript... | |
| 2002 | Patrick K O'Neil, Guoli Sun, Hong Yu, Yacov Ron, Joseph P Dougherty, Bradley D Preston | Mutational analysis of HIV-1 long ter... | |
| 2002 | Joke Snoeck, Sonia Van Dooren, Kristel Van Laethem, Inge Derdelinckx, Eric Van Wijngaerden, Erik De Clercq, Anne-Mieke Vandamme | Prevalence and origin of HIV-1 group ... | |
| 2002 | Brigitte Montes, Michel Segondy | Prevalence of the mutational pattern ... | |
| 2002 | Erik De Clercq | New developments in anti-HIV chemothe... | |
| 2002 | Adrian S Ray, Aravind Basavapathruni, Karen S Anderson | Mechanistic studies to understand the... | |
| 2002 | Janina Cramer, Michael Strerath, Andreas Marx, Tobias Restle | Exploring the effects of active site ... | RT,Associated condition,All properties |
| 2001 | I A Drachkova, Irina O Petruseva, I V Safronov, A L Zakharenko, G V Shishkin, Olga I Lavrik, Svetlana N Khodyreva | [Reagents for modification of protein... | |
| 2001 | Erik De Clercq | New developments in anti-HIV chemothe... | |
| 2001 | A Martinez, C Gil, A Castro, C Perez, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq | Anti-HIV-1 activity of benzothiadiazi... | |
| 2001 | Stephen H Hughes | Molecular matchmaking: NNRTIs can enh... | |
| 2001 | V Molteni, J Greenwald, D Rhodes, Y Hwang, W Kwiatkowski, F D Bushman, J S Siegel, S Choe | Identification of a small-molecule bi... | |
| 2001 | Donald W Ludovici, Robert W Kavash, Michael J Kukla, Chih Y Ho, Hong Ye, B L De Corte, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, H E Moereels, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Paul J Lewi, Kalyan Das, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | J E Fitzgibbon, B DiCola, Edward Arnold, Kalyan Das, B E Sha, J C Pottage, R Nahass, S Gaur, J F John | HIV-1 reverse transcriptase mutations... | |
| 2001 | Donald W Ludovici, Michael J Kukla, P G Grous, S Krishnan, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Erik De Clercq, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | K E Squires | An introduction to nucleoside and nuc... | |
| 2001 | Joseph H Chan, J S Hong, R N Hunter , G F Orr, Jill R Cowan, D B Sherman, S M Sparks, B E Reitter, C Webster Andrews, Richard J Hazen, M St Clair, Lawrence R Boone, Robert G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, R J Ott, Jingshan Ren, A Hopkins, David I Stuart, David K Stammers | 2-Amino-6-arylsulfonylbenzonitriles a... | |
| 2001 | Z Sevilya, S Loya, Stephen H Hughes, A Hizi | The ribonuclease H activity of the re... | |
| 2001 | Paul L Boyer, Hong Qiang Gao, P Frank, Patrick K Clark, Stephen H Hughes | The basic loop of the RNase H domain ... | |
| 2001 | Matthias Götte, Masanori Kameoka, N McLellan, Luciano Cellai, Mark A. Wainberg | Analysis of efficiency and fidelity o... | |
| 2001 | Lisa K Naeger, Michael D Miller | Mechanisms of HIV-1 nucleoside revers... | |
| 2001 | Paul L Boyer, Hong Qiang Gao, Patrick K Clark, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | YADD mutants of human immunodeficienc... | |
| 2001 | Hiroshi Ohrui, Hiroyuki Mitsuya | 4'-C-substituted-2'-deoxynucleosides:... | |
| 2001 | M Madrid, J A Lukin, J D Madura, Jianping Ding, Edward Arnold | Molecular dynamics of HIV-1 reverse t... | |
| 2001 | L Menéndez-Arias, A Abraha, ME Quiñones-Mateu, Antonio Mas, M J Camarasa, E J Arts | Functional characterization of chimer... | |
| 2001 | Elena N Peletskaya, Paul L Boyer, Alex A Kogon, Patrick K Clark, Heiko Kroth, Jane M Sayer, Donald M Jerina, Stephen H Hughes | Cross-linking of the fingers subdomai... | |
| 2001 | G Tachedjian, M Orlova, Stefan G Sarafianos, Edward Arnold, S P Goff | Nonnucleoside reverse transcriptase i... | |
| 2001 | M D Driscoll, Marie-Pierre Golinelli, Stephen H Hughes | In vitro analysis of human immunodefi... | |
| 2001 | Phillip A Furman, J Jeffrey, L L Kiefer, Joy Y Feng, Karen S Anderson, K Borroto-Esoda, E Hill, William C Copeland, Chung K Chu, J P Sommadossi, I Liberman, Raymond F Schinazi, George R Painter | Mechanism of action of 1-beta-D-2,6-d... | |
| 2001 | Catherine Isel, Chantal Ehresmann, P Walter, Bernard Ehresmann, Roland Marquet | The emergence of different resistance... | |
| 2001 | Giovanni Maga, Anna Ramunno, Vito Nacci, Giada A Locatelli, Silvio Spadari, Isabella Fiorini, Fausto Baldanti, Stefania Paolucci, Maurizio Zavattoni, Alberto Bergamini, Bruno Galletti, S Muck, Ulrich Hubscher, Gianluca Giorgi, G Guiso, S Caccia, Giuseppe Campiani | The stereoselective targeting of a sp... | |
| 2001 | Johan Lennerstrand, Kurt Hertogs, David K Stammers, Brendan A Larder | Correlation between viral resistance ... | |
| 2001 | Erik De Clercq, Dominique Schols | Inhibition of HIV infection by CXCR4 ... | |
| 2001 | R Hobi, Ulrich Hübscher, K Neftel, E Alteri, B Poncioni, M R Walker, K Woods-Cook, P Schneider, J K Lazdins | Anti-HIV-1 activity in vitro of cefta... | |
| 2001 | Wim Pluymers, Erik De Clercq, Zeger Debyser | HIV-1 integration as a target for ant... | |
| 2001 | Masanori Kameoka, Liwei Rong, Matthias Götte, Chen Liang, Rodney S Russell, Mark A. Wainberg | Role for human immunodeficiency virus... | |
| 2001 | M Gutiérrez-Rivas, L Menéndez-Arias | A mutation in the primer grip region ... | |
| 2001 | Taurai Tasara, Giovanni Maga, Michael O Hottiger, Ulrich Hübscher | HIV-1 reverse transcriptase and integ... | |
| 2001 | Jan Balzarini, María-José Camarasa, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, CF Perno, Erik De Clercq, J N Anderson, Anna Karlsson | Exploitation of the low fidelity of h... | |
| 2001 | Donald W Ludovici, B L De Corte, Michael J Kukla, Hong Ye, Chih Y Ho, Mark A Lichtenstein, Robert W Kavash, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Kalyan Das, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | Giuseppe Campiani, F Aiello, M Fabbrini, Elena Morelli, Anna Ramunno, S Armaroli, Vito Nacci, A Garofalo, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, L Ventura, B Bongiovanni, M Capozzi, F Bolacchi, Stefano Marini, Massimo Coletta, G Guiso, S Caccia | Quinoxalinylethylpyridylthioureas (QX... | |
| 2001 | M Lavigne, L Polomack, H Buc | Structures of complexes formed by HIV... | |
| 2001 | Jennifer T Miller, Bernard Ehresmann, Ulrich Hübscher, Stuart F J Le Grice | A novel interaction of tRNA(Lys,3) wi... | |
| 2001 | A L Zakharenko, Dmitry M Kolpashchikov, Svetlana N Khodyreva, Olga I Lavrik, L Menéndez-Arias | Investigation of the dNTP-binding sit... | |
| 2001 | Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Paul L Boyer, Paul Lewi, Paul A J Janssen, Jörg-Peter Kleim, M Rösner, Stephen H Hughes, Edward Arnold | The Lys103Asn mutation of HIV-1 RT: a... | |
| 2001 | Fátima Rodríguez-Barrios, C Pérez, Esther Lobatón, Sonsoles Velázquez, Cristina Chamorro, Ana San-Félix, María-Jesús Pérez-Pérez, María-José Camarasa, H Pelemans, Jan Balzarini, Federico Gago | Identification of a putative binding ... | |
| 2001 | H Pelemans, A Aertsen, Kristel Van Laethem, A-M Vandamme, Erik De Clercq, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, María-José Camarasa, Jan Balzarini | Site-directed mutagenesis of human im... | |
| 2001 | J Y Wang, Hong Ling, Wei Wen Yang, R Craigie | Structure of a two-domain fragment of... | |
| 2001 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Selective excision of AZTMP by drug-r... | |
| 2001 | Liwei Rong, Chen Liang, M Hsu, Xiaofeng Guo, Bernard P Roques, Mark A. Wainberg | HIV-1 nucleocapsid protein and the se... | |
| 2001 | G H Kijak, S E Pampuro, M M Avila, C Zala, P Cahn, Mark A. Wainberg, H Salomón | Resistance profiles to antiretroviral... | |
| 2001 | Li Fan, Laurie S Kaguni | Multiple regions of subunit interacti... | |
| 2001 | J L Hammond, D L Koontz, Holly Z Bazmi, J R Beadle, S E Hostetler, G D Kini, Kathy A Aldern, Douglas D Richman, Karl Y Hostetler, John W Mellors | Alkylglycerol prodrugs of phosphonofo... | |
| 2001 | Ei-Ichi Kodama, Satoru Kohgo, Kenji Kitano, H Machida, Hiroyuki Gatanaga, S Shigeta, Masao Matsuoka, Hiroshi Ohrui, Hiroyuki Mitsuya | 4'-Ethynyl nucleoside analogs: potent... | |
| 2001 | Jingshan Ren, C Nichols, L Bird, P Chamberlain, Kurt L Weaver, S Short, David I Stuart, David K Stammers | Structural mechanisms of drug resista... | |
| 2001 | Alba Chimirri, Pietro Monforte, Angela Rao, Maria Zappalà, Anna-Maria Monforte, G De Sarro, Christophe Pannecouque, Myriam Witvrouw, Jan Balzarini, Erik De Clercq | Synthesis, biological activity, pharm... | |
| 2001 | Jan Balzarini, Erik De Clercq | Rapid alternation of drug therapy is ... | |
| 2001 | Cristina Chamorro, Esther Lobatón, María-Cruz Bonache, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, Ana San-Félix, María-José Camarasa | Identification of a novel family of n... | |
| 2001 | H Pelemans, Robert Esnouf, K L Min, M Parniak, Erik De Clercq, Jan Balzarini | Mutations at amino acid positions 63,... | |
| 2001 | Stefan G Sarafianos, Kalyan Das, C Tantillo, Arthur D Clark, Jianping Ding, J M Whitcomb, Paul L Boyer, Stephen H Hughes, Edward Arnold | Crystal structure of HIV-1 reverse tr... | |
| 2001 | Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | RNase H cleavage of the 5' end of the... | |
| 2000 | W R Davis, J Tomsho, S Nikam, E M Cook, D Somand, J A Peliska | Inhibition of HIV-1 reverse transcrip... | |
| 2000 | Neerja Kaushik, K Chowdhury, V N Pandey, Mukund J Modak | Valine of the YVDD motif of moloney m... | |
| 2000 | D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando | Drug resistance and drug combination ... | |
| 2000 | G J Latham, E Forgacs, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd | Vertical-scanning mutagenesis of a cr... | |
| 2000 | A J Brown, H M Precious, Jeannette M Whitcomb, J K Wong, M Quigg, Wei Huang, E S Daar, R T D'Aquila, P H Keiser, E Connick, Nicholas S Hellmann, Christos J Petropoulos, Douglas D Richman, S J Little | Reduced susceptibility of human immun... | |
| 2000 | E P Coakley, J M Gillis, S M Hammer | Phenotypic and genotypic resistance p... | |
| 2000 | C E Cases-Gonzalez, M Gutierrez-Rivas, L Menéndez-Arias | Coupling ribose selection to fidelity... | |
| 2000 | Michael A. Parniak, Nicolas Sluis-Cremer | Inhibitors of HIV-1 reverse transcrip... | |
| 2000 | T Imamichi, T Sinha, H Imamichi, Y M Zhang, J A Metcalf, J Falloon, H C Lane | High-level resistance to 3'-azido-3'-... | |
| 2000 | Christos J Petropoulos, N T Parkin, K L Limoli, Y S Lie, Terri Wrin, Wei Huang, H Tian, D Smith, G A Winslow, D J Capon, Jeannette M Whitcomb | A novel phenotypic drug susceptibilit... | |
| 2000 | Matthias Götte, Mark A. Wainberg | Biochemical mechanisms involved in ov... | |
| 2000 | H Jonckheere, Erik De Clercq, J Anné | Fidelity analysis of HIV-1 reverse tr... | |
| 2000 | Myriam Witvrouw, Valery Fikkert, Wim Pluymers, B Matthews, K Mardel, Dominique Schols, J Raff, Zeger Debyser, Erik De Clercq, G Holan, Christophe Pannecouque | Polyanionic (i.e., polysulfonate) den... | |
| 2000 | Myriam Witvrouw, Christophe Pannecouque, J Desmyter, Erik De Clercq, Koen Andries | In vitro evaluation of the effect of ... | |
| 2000 | A Casimiro-Garcia, Erik De Clercq, Christophe Pannecouque, Myriam Witvrouw, T L Stup, J A Turpin, Robert W Buckheit, Mark Cushman | Synthesis and anti-HIV activity of co... | |
| 2000 | H Jonckheere, J Anné, Erik De Clercq | The HIV-1 reverse transcription (RT) ... | |
| 2000 | L T Bacheler, E D Anton, P Kudish, D Baker, J Bunville, K Krakowski, L Bolling, M Aujay, X V Wang, D Ellis, M F Becker, A L Lasut, H J George, D R Spalding, G Hollis, K Abremski | Human immunodeficiency virus type 1 m... | |
| 2000 | Erik De Clercq | Current lead natural products for the... | |
| 2000 | Antonio Mas, M Parera, C Briones, V Soriano, Miguel Angel Martínez, Esteban Domingo, L Menéndez-Arias | Role of a dipeptide insertion between... | |
| 2000 | Kristel Van Laethem, J C Schmit, H Pelemans, Jan Balzarini, Myriam Witvrouw, María-Jesús Pérez-Pérez, María-José Camarasa, R M Esnouf, Stefano Aquaro, A Cenci, CF Perno, P Hermans, S Sprecher, L Ruiz, B Clotet, Eric Van Wijngaerden, M Van Ranst, J Desmyter, Erik De Clercq, A-M Vandamme | Presence of 2',5'-Bis-O-(tert-butyldi... | |
| 2000 | Lawrence A Loeb, J I Mullins | Lethal mutagenesis of HIV by mutageni... | |
| 2000 | Jan Balzarini, Erik De Clercq, A Carbonez, V Burt, Jörg-Peter Kleim | Long-term exposure of HIV type 1-infe... | |
| 2000 | S Najmudin, Marie L Coté, D Sun, S Yohannan, Sherwin P Montano, J Gu, Millie M Georgiadis | Crystal structures of an N-terminal f... | |
| 2000 | H Pelemans, Robert Esnouf, Erik De Clercq, Jan Balzarini | Mutational analysis of trp-229 of hum... | |
| 2000 | L Mu, Stefan G Sarafianos, Marc C Nicklaus, P Russ, Maqbool A Siddiqui, H Ford, Hiroyuki Mitsuya, R Le, Eiichi N Kodama, Chris Meier, T Knispel, L Anderson, Joseph J Barchi, Victor E Marquez | Interactions of conformationally bias... | |
| 2000 | K Van Vaerenbergh, Kristel Van Laethem, J Albert, Charles A B Boucher, B Clotet, M Floridia, J Gerstoft, B Hejdeman, C Nielsen, Christophe Pannecouque, L Perrin, M F Pirillo, L Ruiz, J C Schmit, F Schneider, A Schoolmeester, Rob Schuurman, H J Stellbrink, L Stuyver, J Van Lunzen, Barbara Van Remoortel, Eric Van Wijngaerden, S Vella, Myriam Witvrouw, Sabine Yerly, Erik De Clercq, J Destmyer, Anne-Mieke Vandamme | Prevalence and characteristics of mul... | |
| 2000 | Jingshan Ren, John Milton, Kurt L Weaver, Steven A Short, David I Stuart, David K Stammers | Structural basis for the resilience o... | |
| 2000 | Hong Qiang Gao, Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | The role of steric hindrance in 3TC r... | |
| 2000 | P Bonfanti, I Faggion, S La Seta Catamancio, M Violin, C Balotta, S Rusconi | Response to antiretroviral therapy in... | |
| 2000 | Peter R Meyer, Suzanne E Matsuura, Raymond F Schinazi, Antero G So, Walter A Scott | Differential removal of thymidine nuc... | |
| 2000 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Analysis of mutations at positions 11... | |
| 2000 | Nicolas Sluis-Cremer, G I Dmitrienko, Jan Balzarini, María-José Camarasa, Michael A. Parniak | Human immunodeficiency virus type 1 r... | |
| 2000 | Paul L Boyer, Stephen H Hughes | Effects of amino acid substitutions a... | |
| 2000 | N Richard, H Salomon, Maureen Oliveira, R Rando, T Mansour, Z Gu, Mark A. Wainberg | Selection of resistance-conferring mu... | |
| 2000 | K Nozawa, Motoshi Suzuki, Masaharu Takemura, Shonen Yoshida | In vitro expansion of mammalian telom... | |
| 2000 | F S Shah, Kenneth A Curr, Monica E Hamburgh, M Parniak, Hiroyuki Mitsuya, J G Arnez, Vinayaka R Prasad | Differential influence of nucleoside ... | |
| 2000 | C de Mendoza, V Soriano, C Briones, O Gallego, P Barreiro, A Alvarez, J González-Lahoz | Emergence of zidovudine resistance in... | |
| 2000 | A Khorchid, H Javanbakht, S Wise, R Halwani, Michael A. Parniak, Mark A. Wainberg, Lawrence Kleiman | Sequences within Pr160gag-pol affecti... | |
| 2000 | N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of hum... | |
| 2000 | T V Rao, M T Haber, Jane M Sayer, Donald M Jerina | Incorporation of 4-thiothymidine into... | |
| 2000 | P Richard Harrigan, C Stone, P Griffin, I Nájera, Stuart Bloor, S Kemp, M Tisdale, Brendan A Larder | Resistance profile of the human immun... | |
| 2000 | Jingshan Ren, J Diprose, J Warren, R M Esnouf, Louise E Bird, Shinji Ikemizu, M Slater, John Milton, Jan Balzarini, David I Stuart, David K Stammers | Phenylethylthiazolylthiourea (PETT) n... | |
| 2000 | A-M Vandamme, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Kristel Van Laethem, J C Schmit, J Desmyter, Erik De Clercq | Evaluating Clinical Isolates for Thei... | |
| 2000 | Dominique Arion, Nicolas Sluis-Cremer, Michael A. Parniak | Mechanism by which phosphonoformic ac... | |
| 2000 | Kurt Hertogs, Stuart Bloor, V De Vroey, C van Den Eynde, Pascale Dehertogh, A van Cauwenberge, Martin Stürmer, T Alcorn, S Wegner, M van Houtte, V Miller, Brendan A Larder | A novel human immunodeficiency virus ... | |
| 2000 | Nicolas Sluis-Cremer, Dominique Arion, Neerja Kaushik, H Lim, Michael A. Parniak | Mutational analysis of Lys65 of HIV-1... | |
| 2000 | Kamalendra Singh, Neerja Kaushik, J Jin, M Madhusudanan, Mukund J Modak | Role of Q190 of MuLV RT in ddNTP resi... | |
| 2000 | Matthias Götte, Dominique Arion, Michael A. Parniak, Mark A. Wainberg | The M184V mutation in the reverse tra... | |
| 2000 | Neerja Kaushik, T T Talele, P K Pandey, D Harris, P N Yadav, V N Pandey | Role of glutamine 151 of human immuno... | |
| 2000 | Bluma G Brenner, Mark A. Wainberg, H Salomon, D Rouleau, A Dascal, Bonnie Spira, Rafick-Pierre Sekaly, Brian Conway, Jean-Pierre Routy | Resistance to antiretroviral drugs in... | |
| 2000 | Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak | Molecular mechanisms of HIV-1 resista... | |
| 2000 | V Miller, M Ait-Khaled, C Stone, P Griffin, D Mesogiti, A Cutrell, R Harrigan, Schlomo Staszewski, C Katlama, G Pearce, M Tisdale | HIV-1 reverse transcriptase (RT) geno... | |
| 2000 | H Salomon, Mark A. Wainberg, Bluma G Brenner, Yudong Quan, D Rouleau, P Coté, R LeBlanc, E Lefebvre, Bonnie Spira, C Tsoukas, Rafick-Pierre Sekaly, Brian Conway, D Mayers, Jean-Pierre Routy | Prevalence of HIV-1 resistant to anti... | |
| 2000 | Mickael Rigourd, J M Lanchy, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann, Roland Marquet | Inhibition of the initiation of HIV-1... | |
| 2000 | Ming Yu, W Kabat, Jian Wang | [Rapid detection of drug resistant HI... | |
| 2000 | Holly Z Bazmi, J L Hammond, S C Cavalcanti, Chung K Chu, Raymond F Schinazi, John W Mellors | In vitro selection of mutations in th... | |
| 2000 | Giuseppe Campiani, M Fabbrini, Elena Morelli, Vito Nacci, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, C Fracasso, S Caccia | Non-nucleoside HIV-1 reverse transcri... | |
| 2000 | K K Weiss, S J Isaacs, N H Tran, Elinor T Adman, Baek Kim | Molecular architecture of the mutagen... | |
| 2000 | Jan Balzarini | Evaluation of Compounds Against Recom... | |
| 2000 | Jingshan Ren, C Nichols, Louise E Bird, Tsuyoshi Fujiwara, H Sugimoto, David I Stuart, David K Stammers | Binding of the second generation non-... | |
| 1999 | J J de Jong, J Goudsmit, V V Lukashov, M E Hillebrand, E Baan, R Huismans, Sven A Danner, J H ten Veen, F de Wolf, Suzanne Jurriaans | Insertion of two amino acids combined... | |
| 1999 | P F Lin, C J González, B Griffith, G Friedland, V Calvez, F Ferchal, Raymond F Schinazi, D H Shepp, A B Ashraf, Mark A. Wainberg, V Soriano, John W Mellors, R J Colonno | Stavudine resistance: an update on su... | |
| 1999 | Neerja Kaushik, Kamalendra Singh, I Alluru, Mukund J Modak | Tyrosine 222, a member of the YXDD mo... | |
| 1999 | H Idriss, S Kawa, Z Damuni, E B Thompson, Samuel H Wilson | HIV-1 reverse transcriptase is phosph... | |
| 1999 | Brendan A Larder, Stuart Bloor, S D Kemp, Kurt Hertogs, R L Desmet, V Miller, M Sturmer, Schlomo Staszewski, Jingshan Ren, David K Stammers, David I Stuart, Rudi Pauwels | A family of insertion mutations betwe... | |
| 1999 | Matthias Götte, G Maier, A M Onori, Luciano Cellai, Mark A. Wainberg, H Heumann | Temporal coordination between initiat... | |
| 1999 | S Cen, Yangxin Huang, A Khorchid, J L Darlix, Mark A. Wainberg, Lawrence Kleiman | The role of Pr55(gag) in the annealin... | |
| 1999 | D A Lewis, Katarzyna Bebenek, William A Beard, Samuel H Wilson, Thomas A Kunkel | Uniquely altered DNA replication fide... | |
| 1999 | Giuseppe Campiani, Elena Morelli, M Fabbrini, Vito Nacci, Giovanni Greco, Ettore Novellino, Anna Ramunno, Giovanni Maga, Silvio Spadari, G Caliendo, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, A Nacca, S Caccia | Pyrrolobenzoxazepinone derivatives as... | |
| 1999 | T Szyperski, Matthias Götte, M Billeter, E Perola, Luciano Cellai, H Heumann, K Wüthrich | NMR structure of the chimeric hybrid ... | |
| 1999 | J M de Muys, H Gourdeau, N Nguyen-Ba, D L Taylor, P S Ahmed, T Mansour, C Locas, N Richard, Mark A. Wainberg, R F Rando | Anti-human immunodeficiency virus typ... | |
| 1999 | I Pellegrin, J Izopet, J Reynes, M Denayrolles, Brigitte Montes, J L Pellegrin, P Massip, J Puel, H Fleury, Michel Segondy | Emergence of zidovudine and multidrug... | |
| 1999 | M Wisniewski, C Palaniappan, Z Fu, Stuart F J Le Grice, P Fay, Robert A Bambara | Mutations in the primer grip region o... | |
| 1999 | Baek Kim, J C Ayran, S G Sagar, Elinor T Adman, S M Fuller, N H Tran, J Horrigan | New human immunodeficiency virus, typ... | |
| 1999 | N Richar, Yudong Quan, H Salomon, M Hsu, J Bedard, P Richard Harrigan, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of HIV... | |
| 1999 | Zucai Suo, S J Lippard, Kenneth A Johnson | Single d(GpG)/cis-diammineplatinum(II... | |
| 1999 | Alexandra Vaisman, Susan E Lim, S M Patrick, William C Copeland, David C Hinkle, J J Turchi, Stephen G Chaney | Effect of DNA polymerases and high mo... | |
| 1999 | Katarzyna Bebenek, J C Boyer, Thomas A Kunkel | The base substitution fidelity of HIV... | |
| 1999 | M Högberg, Christer Sahlberg, P Engelhardt, Rolf Noréen, J Kangasmetsä, N G Johansson, Bo Oberg, L Vrang, Haijiang Zhang, B L Sahlberg, Torsten Unge, S Lövgren, Kerstin Fridborg, K Bäckbro | Urea-PETT compounds as a new class of... | |
| 1999 | Sylvie Doublié, M R Sawaya, Tom Ellenberger | An open and closed case for all polym... | |
| 1999 | Lawrence A Loeb, J M Essigmann, F Kazazi, Jun Zhang, K D Rose, J I Mullins | Lethal mutagenesis of HIV with mutage... | |
| 1999 | L L Furge, F Peter Guengerich | Explanation of pre-steady-state kinet... | |
| 1999 | Mark A. Wainberg, Michael D Miller, Yudong Quan, H Salomon, A S Mulato, P D Lamy, Nicolas A Margot, K E Anton, J M Cherrington | In vitro selection and characterizati... | |
| 1999 | M E Arranz, J A Díaz, S T Ingate, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, S Vega | Synthesis and anti-HIV activity of 1,... | |
| 1999 | Andreas Marx, M Spichty, Mario Amacker, U Schwitter, Ulrich Hübscher, Thomas A Bickle, Giovanni Maga, Bernd Giese | Probing interactions between HIV-1 re... | |
| 1999 | Andrew L Hopkins, Jingshan Ren, Hiromichi Tanaka, Masanori Baba, M Okamato, David I Stuart, David K Stammers | Design of MKC-442 (emivirine) analogu... | |
| 1999 | Dominique Arion, Michael A. Parniak | HIV resistance to zidovudine: the rol... | |
| 1999 | Taurai Tasara, Mario Amacker, Ulrich Hübscher | Intramolecular chimeras of the p51 su... | |
| 1999 | Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari | Molecular basis for the enantioselect... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Arthur D Clark, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Lamivudine (3TC) resistance in HIV-1 ... | |
| 1999 | Z Gu, Mark A. Wainberg, N Nguyen-Ba, L L'Heureux, J M de Muys, T L Bowlin, R F Rando | Mechanism of action and in vitro acti... | |
| 1999 | Peter R Meyer, Suzanne E Matsuura, A M Mian, Antero G So, Walter A Scott | A mechanism of AZT resistance: an inc... | |
| 1999 | H Rübsamen-Waigmann, E Huguenel, A Shah, A Paessens, H J Ruoff, H von Briesen, A Immelmann, U Dietrich, Mark A. Wainberg | Resistance mutations selected in vivo... | |
| 1999 | G Borkow, Dominique Arion, Mark A. Wainberg, Michael A. Parniak | The thiocarboxanilide nonnucleoside i... | |
| 1999 | M D Powell, William A Beard, Katarzyna Bebenek, K J Howard, Stuart F J Le Grice, Thomas A Darden, Thomas A Kunkel, Samuel H Wilson, J G Levin | Residues in the alphaH and alphaI hel... | |
| 1999 | Joy Y Feng, Karen S Anderson | Mechanistic studies comparing the inc... | |
| 1999 | J Izopet, A Bicart-See, C Pasquier, K Sandres, E Bonnet, B Marchou, J Puel, P Massip | Mutations conferring resistance to zi... | |
| 1999 | A Rakik, M Ait-Khaled, P Griffin, T A Thomas, M Tisdale, Jörg-Peter Kleim | A novel genotype encoding a single am... | |
| 1999 | Thomas A Steitz | DNA polymerases: structural diversity... | |
| 1999 | Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | Action of a new mammalian DNA polymer... | |
| 1999 | Paul L Boyer, J Lisziewicz, F Lori, Stephen H Hughes | Analysis of amino insertion mutations... | |
| 1999 | Michael D Miller, K E Anton, A S Mulato, P D Lamy, J M Cherrington | Human immunodeficiency virus type 1 e... | |
| 1999 | Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Similarities and differences in the R... | |
| 1999 | Yudong Quan, Liwei Rong, Chen Liang, Mark A. Wainberg | Reverse transcriptase inhibitors can ... | |
| 1999 | Y Goldgur, R Craigie, G H Cohen, Tsuyoshi Fujiwara, T Yoshinaga, T Fujishita, H Sugimoto, T Endo, H Murai, D R Davies | Structure of the HIV-1 integrase cata... | |
| 1999 | Sonsoles Velázquez, V Tuñón, M L Jimeno, Cristina Chamorro, Erik De Clercq, Jan Balzarini, María-José Camarasa | Potential multifunctional inhibitors ... | |
| 1999 | Jan Balzarini | Suppression of resistance to drugs ta... | |
| 1999 | M Madrid, A Jacobo-Molina, Jianping Ding, Edward Arnold | Major subdomain rearrangement in HIV-... | |
| 1999 | Yudong Quan, Dimitrios Motakis, R Buckheit, Z Q Xu, M T Flavin, Michael A. Parniak, Mark A. Wainberg | Sensitivity and resistance to (+)-cal... | |
| 1999 | Junxing Shi, J J McAtee, S Schlueter Wirtz, P Tharnish, A Juodawlkis, Dennis C Liotta, Raymond F Schinazi | Synthesis and biological evaluation o... | |
| 1999 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, David I Stuart, David K Stammers | Crystallographic analysis of the bind... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Touching the heart of HIV-1 drug resi... | |
| 1999 | Myriam Witvrouw, Christophe Pannecouque, Erik De Clercq, E Fernández-Alvarez, J L Marco | Inhibition of human immunodeficiency ... | |
| 1999 | Myriam Witvrouw, Christophe Pannecouque, Kristel Van Laethem, J Desmyter, Erik De Clercq, Anne-Mieke Vandamme | Activity of non-nucleoside reverse tr... | |
| 1999 | Matthias Götte, Xincang Li, Mark A. Wainberg | HIV-1 reverse transcription: a brief ... | |
| 1998 | P Inouye, E Cherry, M Hsu, S Zolla-Pazner, Mark A. Wainberg | Neutralizing antibodies directed agai... | |
| 1998 | H Kwon, N Pelletier, C DeLuca, P Genin, S Cisternas, R Lin, Mark A. Wainberg, J Hiscott | Inducible expression of IkappaBalpha ... | |
| 1998 | Cristina Chamorro, María-José Camarasa, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, Ana San Félix | An approach towards the synthesis of ... | |
| 1998 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, J Warren, Jan Balzarini, David I Stuart, David K Stammers | Crystal structures of HIV-1 reverse t... | |
| 1998 | M Wasner, Dominique Arion, G Borkow, A Noronha, A H Uddin, Michael A. Parniak, Masad J Damha | Physicochemical and biochemical prope... | |
| 1998 | Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | Sulfoquinovosyldiacylglycerol, KM043,... | |
| 1998 | Akitsu Ogawa, Takashi Murate, Shunji Izuta, Masaharu Takemura, Kyoji Furuta, Jun'ichi Kobayashi, T Kamikawa, Y Nimura, Shonen Yoshida | Sulfated glycoglycerolipid from archa... | |
| 1998 | Yoshiyuki Mizushina, L Hanashima, Tsuyoshi Yamaguchi, Masaharu Takemura, Fumio Sugawara, Mineo Saneyoshi, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | A mushroom fruiting body-inducing sub... | |
| 1998 | Jianping Ding, Kalyan Das, Y Hsiou, Stefan G Sarafianos, Arthur D Clark, A Jacobo-Molina, C Tantillo, Stephen H Hughes, Edward Arnold | Structure and functional implications... | |
| 1998 | Michael D Miller, P D Lamy, M D Fuller, A S Mulato, Nicolas A Margot, T Cihlar, J M Cherrington | Human immunodeficiency virus type 1 r... | |
| 1998 | Y Hsiou, Kalyan Das, Jianping Ding, Arthur D Clark, Jörg-Peter Kleim, M Rösner, I Winkler, G Riess, Stephen H Hughes, Edward Arnold | Structures of Tyr188Leu mutant and wi... | |
| 1998 | Erik De Clercq | The role of non-nucleoside reverse tr... | |
| 1998 | F J Palella, K M Delaney, A C Moorman, M O Loveless, J Fuhrer, G A Satten, D J Aschman, S D Holmberg | Declining morbidity and mortality amo... | |
| 1998 | D V Nissley, Paul L Boyer, D J Garfinkel, Stephen H Hughes, J N Strathern | Hybrid Ty1/HIV-1 elements used to det... | |
| 1998 | Yudong Quan, P Inouye, Chen Liang, Liwei Rong, Matthias Götte, Mark A. Wainberg | Dominance of the E89G substitution in... | |
| 1998 | I Choudhury, Jianhong Wang, A B Rabson, S Stein, S Pooyan, S Stein, M J Leibowitz | Inhibition of HIV-1 replication by a ... | |
| 1998 | S W Graves, Allison A Johnson, Kenneth A Johnson | Expression, purification, and initial... | Processivity,Kd,Vmax,All properties |
| 1998 | Monica E Hamburgh, William C Drosopoulos, Vinayaka R Prasad | The influence of 3TC-resistance mutat... | |
| 1998 | Kamalendra Singh, Mukund J Modak | A unified DNA- and dNTP-binding mode ... | |
| 1998 | William A Beard, Katarzyna Bebenek, Thomas A Darden, Lin Li, Rajendra Prasad, Thomas A Kunkel, Samuel H Wilson | Vertical-scanning mutagenesis of a cr... | |
| 1998 | G Tachedjian, John W Mellors, H Bazmi, J Mills | Impaired fitness of foscarnet-resista... | |
| 1998 | Andreas Marx, Mario Amacker, M Stucki, Ulrich Hübscher, Thomas A Bickle, Bernd Giese | 4'-Acylated thymidine 5'-triphosphate... | |
| 1998 | Mario Amacker, Ulrich Hübscher | Chimeric HIV-1 and feline immunodefic... | |
| 1998 | M von Janta-Lipinski, B Costisella, H Ochs, Ulrich Hübscher, P Hafkemeyer, E Matthes | Newly synthesized L-enantiomers of 3'... | |
| 1998 | Joachim Jaeger, Tobias Restle, Thomas A Steitz | The structure of HIV-1 reverse transc... | |
| 1998 | Silvio Spadari, Giovanni Maga, A Verri, Federico Focher | Molecular basis for the antiviral and... | |
| 1998 | J C Schmit, L Ruiz, L Stuyver, Kristel Van Laethem, I Vanderlinden, T Puig, R Rossau, J Desmyter, Erik De Clercq, B Clotet, A-M Vandamme | Comparison of the LiPA HIV-1 RT test,... | |
| 1998 | Hao Huang, R Chopra, G L Verdine, S C Harrison | Structure of a covalently trapped cat... | |
| 1998 | M A Winters, K L Coolley, Y A Girard, D J Levee, H Hamdan, R W Shafer, D A Katzenstein, T C Merigan | A 6-basepair insert in the reverse tr... | |
| 1998 | Myriam Witvrouw, M E Arranz, Christophe Pannecouque, R Declercq, H Jonckheere, J C Schmit, A-M Vandamme, J A Diaz, S T Ingate, J Desmyter, Robert Esnouf, L Van Meervelt, S Vega, Jan Balzarini, Erik De Clercq | 1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,... | |
| 1998 | H Jonckheere, Myriam Witvrouw, Erik De Clercq, J Anné | Lamivudine resistance of HIV type 1 d... | |
| 1998 | Dominique Arion, Neerja Kaushik, Suzanne McCormick, G Borkow, Michael A. Parniak | Phenotypic mechanism of HIV-1 resista... | |
| 1998 | L M Demeter, P M Meehan, G Morse, M A Fischl, M Para, W Powderly, J Leedom, J Holden-Wiltse, C Greisberger, K Wood, J Timpone, L K Wathen, T Nevin, L Resnick, D H Batts, R C Reichman | Phase I study of atevirdine mesylate ... | |
| 1998 | H J Einolf, N Schnetz-Boutaud, F Peter Guengerich | Steady-state and pre-steady-state kin... | |
| 1998 | C Tamalet, J Izopet, N Koch, J Fantini, N Yahi | Stable rearrangements of the beta3-be... | |
| 1998 | H Togashi, Yoshiyuki Mizushina, Masaharu Takemura, Fumio Sugawara, Hiroyuki Koshino, Y Esumi, J Uzawa, H Kumagai, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | 4-Hydroxy-17-methylincisterol, an inh... | |
| 1998 | Mark Cushman, A Casimiro-Garcia, E Hejchman, J A Ruell, M Huang, C A Schaeffer, K Williamson, W G Rice, Robert W Buckheit | New alkenyldiarylmethanes with enhanc... | |
| 1998 | Erik De Clercq | New perspectives for the treatment of... | |
| 1998 | Matthias Götte, G Maier, H J Gross, H Heumann | Localization of the active site of HI... | |
| 1998 | Zucai Suo, Kenneth A Johnson | DNA secondary structure effects on DN... | |
| 1998 | William C Drosopoulos, Lisa F Rezende, Mark A. Wainberg, Vinayaka R Prasad | Virtues of being faithful: can we lim... | |
| 1998 | A Acel, B E Udashkin, Mark A. Wainberg, E A Faust | Efficient gap repair catalyzed in vit... | |
| 1998 | Hong Qiang Gao, Paul L Boyer, Edward Arnold, Stephen H Hughes | Effects of mutations in the polymeras... | |
| 1998 | D Harris, Neerja Kaushik, P K Pandey, P N Yadav, V N Pandey | Functional analysis of amino acid res... | |
| 1998 | E Cherry, N Morin, Mark A. Wainberg | Effect of HIV constructs containing p... | |
| 1998 | Zucai Suo, Kenneth A Johnson | Selective inhibition of HIV-1 reverse... | |
| 1998 | D Harris, P N Yadav, V N Pandey | Loss of polymerase activity due to Ty... | |
| 1998 | Baek Kim, T R Hathaway, Lawrence A Loeb | Fidelity of mutant HIV-1 reverse tran... | |
| 1998 | Yudong Quan, Chen Liang, P Inouye, Mark A. Wainberg | Enhanced impairment of chain elongati... | |
| 1998 | H Salomon, Julio S G Montaner, A Belmonte, Mark A. Wainberg | Diminished HIV-1 sensitivity to stavu... | |
| 1998 | Bruno Canard, S R Sarfati, Charles C Richardson | Enhanced binding of azidothymidine-re... | |
| 1998 | H Pelemans, R M Esnouf, Michael A. Parniak, A-M Vandamme, Erik De Clercq, Jan Balzarini | A proline-to-histidine substitution a... | |
| 1998 | C Katlama, M A Valantin, S Matheron, A Coutellier, V Calvez, D Descamps, C Longuet, M Bonmarchand, R Tubiana, M De Sa, R Lancar, Henri Agut, F Brun-Vezinet, D Costagliola | Efficacy and tolerability of stavudin... | |
| 1998 | Tsuyoshi Fujiwara, Akira Sato, M el-Farrash, S Miki, K Abe, Y Isaka, M Kodama, Y Wu, L B Chen, H Harada, H Sugimoto, Masami Hatanaka, Y Hinuma | S-1153 inhibits replication of known ... | |
| 1998 | Peter R Meyer, Suzanne E Matsuura, Antero G So, Walter A Scott | Unblocking of chain-terminated primer... | |
| 1998 | E Cherry, Chen Liang, Liwei Rong, Yudong Quan, P Inouye, Xincang Li, N Morin, M Kotler, Mark A. Wainberg | Characterization of human immunodefic... | |
| 1998 | Yudong Quan, Z Gu, Xincang Li, Chen Liang, Michael A. Parniak, Mark A. Wainberg | Endogenous reverse transcriptase assa... | |
| 1998 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, E Yvonne Jones, I Kirby, J Keeling, C K Ross, Brendan A Larder, David I Stuart, David K Stammers | 3'-Azido-3'-deoxythymidine drug resis... | |
| 1998 | Sonsoles Velázquez, Cristina Chamorro, María-Jesús Pérez-Pérez, R Alvarez, M L Jimeno, A Martín-Domenech, C Pérez, Federico Gago, Erik De Clercq, Jan Balzarini, Ana San-Félix, María-José Camarasa | Abasic analogues of TSAO-T as the fir... | |
| 1998 | Joseph A Vaccaro, Karen S Anderson | Implication of the tRNA initiation st... | |
| 1998 | M Nakayabu, S Miwa, Motoshi Suzuki, Shunji Izuta, G Sobue, Shonen Yoshida | Mismatched nucleotides may facilitate... | |
| 1998 | Paul L Boyer, Hong Qiang Gao, Stephen H Hughes | A mutation at position 190 of human i... | |
| 1997 | F Lori, A G Malykh, A Foli, R Maserati, A De Antoni, L Minoli, D Padrini, A Degli Antoni, E Barchi, H Jessen, Mark A. Wainberg, R C Gallo, J Lisziewicz | Combination of a drug targeting the c... | |
| 1997 | M Hsu, P Inouye, L Rezende, N Richard, Zhongjie Li, Vinayaka R Prasad, Mark A. Wainberg | Higher fidelity of RNA-dependent DNA ... | |
| 1997 | Mark A. Wainberg | Increased fidelity of drug-selected M... | |
| 1997 | J Mak, A Khorchid, Q Cao, Yangxin Huang, I Lowy, Michael A. Parniak, Vinayaka R Prasad, Mark A. Wainberg, Lawrence Kleiman | Effects of mutations in Pr160gag-pol ... | |
| 1997 | M A Winters, R W Shafer, R A Jellinger, G Mamtora, T Gingeras, T C Merigan | Human immunodeficiency virus type 1 r... | |
| 1997 | S G Kerr, Karen S Anderson | Pre-steady-state kinetic characteriza... | |
| 1997 | Takayuki Ueno, Hiroyuki Mitsuya | Comparative enzymatic study of HIV-1 ... | |
| 1997 | A Hizi, Ashwini S Kamath-Loeb, K D Rose, Lawrence A Loeb | Mutagenesis by human immunodeficiency... | |
| 1997 | C Palaniappan, M Wisniewski, P S Jacques, Stuart F J Le Grice, P J Fay, Robert A Bambara | Mutations within the primer grip regi... | |
| 1997 | R Krebs, U Immendörfer, S H Thrall, B M Wöhrl, R S Goody | Single-step kinetics of HIV-1 reverse... | |
| 1997 | G Borkow, Ronald S Fletcher, J Barnard, Dominique Arion, Dimitrios Motakis, G I Dmitrienko, Michael A. Parniak | Inhibition of the ribonuclease H and ... | |
| 1997 | Myriam Witvrouw, Jan Balzarini, Christophe Pannecouque, S Jhaumeer-Laulloo, J A Esté, Dominique Schols, Peter Cherepanov, J C Schmit, Zeger Debyser, A-M Vandamme, J Desmyter, S R Ramadas, Erik De Clercq | SRR-SB3, a disulfide-containing macro... | |
| 1997 | Jianping Ding, Stephen H Hughes, Edward Arnold | Protein-nucleic acid interactions and... | |
| 1997 | G Borkow, J Barnard, T M Nguyen, A Belmonte, Mark A. Wainberg, Michael A. Parniak | Chemical barriers to human immunodefi... | |
| 1997 | Chen Liang, Xincang Li, Liwei Rong, P Inouye, Yudong Quan, Lawrence Kleiman, Mark A. Wainberg | The importance of the A-rich loop in ... | |
| 1997 | L L Furge, F Peter Guengerich | Analysis of nucleotide insertion and ... | |
| 1997 | M Tanaka, R V Srinivas, Takayuki Ueno, M F Kavlick, F K Hui, A Fridland, J S Driscoll, Hiroyuki Mitsuya | In vitro induction of human immunodef... | |
| 1997 | S Loya, Hong Qiang Gao, O Avidan, Paul L Boyer, Stephen H Hughes, A Hizi | Subunit-specific mutagenesis of the c... | |
| 1997 | Neerja Kaushik, D Harris, N Rege, Mukund J Modak, P N Yadav, V N Pandey | Role of glutamine-151 of human immuno... | |
| 1997 | Y M Lin, H Anderson, M T Flavin, Y H Pai, E Mata-Greenwood, T Pengsuparp, J M Pezzuto, Raymond F Schinazi, Stephen H Hughes, F C Chen | In vitro anti-HIV activity of biflavo... | |
| 1997 | I V Safronov, N V Shcherbik, Svetlana N Khodyreva, V A Vlasov, M I Dobrikov, G V Shishkin, Olga I Lavrik | [New photoreactive N(4)-substituted d... | |
| 1997 | Chen Liang, Liwei Rong, N Morin, E Cherry, Yangxin Huang, Lawrence Kleiman, Mark A. Wainberg | The roles of the human immunodeficien... | |
| 1997 | H Pelemans, Robert Esnouf, A Dunkler, Michael A. Parniak, A-M Vandamme, Anna Karlsson, Erik De Clercq, Jörg-Peter Kleim, Jan Balzarini | Characteristics of the Pro225His muta... | |
| 1997 | J Barnard, G Borkow, Michael A. Parniak | The thiocarboxanilide nonnucleoside U... | |
| 1997 | Yoshiyuki Mizushina, Shonen Yoshida, Akio Matsukage, Kengo Sakaguchi | The inhibitory action of fatty acids ... | |
| 1997 | Erik De Clercq | Development of resistance of human im... | |
| 1997 | Myriam Witvrouw, Erik De Clercq | Sulfated polysaccharides extracted fr... | |
| 1997 | Thomas Roth, Marshall L Morningstar, Paul L Boyer, Stephen H Hughes, Robert W Buckheit, Christopher J Michejda | Synthesis and biological activity of ... | |
| 1997 | Bruno Canard, R Sarfati, Charles C Richardson | Binding of RNA template to a complex ... | |
| 1997 | Robert W Buckheit, M J Snow, V Fliakas-Boltz, T L Kinjerski, J D Russell, L A Pallansch, W G Brouwer, S S Yang | Highly potent oxathiin carboxanilide ... | |
| 1997 | Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, Koen Andries, Robert W Buckheit, Richard H Smith | Molecular modeling of HIV-1 reverse t... | |
| 1997 | Giovanni Maga, Mario Amacker, N Ruel, Ulrich Hübscher, Silvio Spadari | Resistance to nevirapine of HIV-1 rev... | |
| 1997 | T Rubinek, M Bakhanashvili, R Taube, O Avidan, A Hizi | The fidelity of 3' misinsertion and m... | |
| 1997 | E Forgacs, G Latham, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd | Probing structure/function relationsh... | |
| 1997 | G Gao, M Orlova, Millie M Georgiadis, W A Hendrickson, S P Goff | Conferring RNA polymerase activity to... | |
| 1997 | G Borkow, Dominique Arion, A Noronha, M Scartozzi, Masad J Damha, Michael A. Parniak | Inhibitory potency of R-region specif... | |
| 1997 | R M Esnouf, Jingshan Ren, Andrew L Hopkins, C K Ross, E Yvonne Jones, David K Stammers, David I Stuart | Unique features in the structure of t... | |
| 1997 | W Tong, C D Lu, S K Sharma, S Matsuura, Antero G So, Walter A Scott | Nucleotide-induced stable complex for... | |
| 1997 | Stefano Aquaro, CF Perno, Emanuela Balestra, Jan Balzarini, A Cenci, M Francesconi, S Panti, F Serra, N Villani, Raffaele Caliò | Inhibition of replication of HIV in p... | |
| 1997 | Jan Balzarini, Erik De Clercq, K Uberla | SIV/HIV-1 hybrid virus expressing the... | |
| 1997 | B P Burnett, Charles S McHenry | Posttranscriptional modification of r... | |
| 1997 | Mario Amacker, M Hottiger, R Mossi, Ulrich Hübscher | HIV-1 nucleocapsid protein and replic... | |
| 1997 | Zucai Suo, Kenneth A Johnson | Effect of RNA secondary structure on ... | |
| 1997 | M Tisdale, T Alnadaf, D Cousens | Combination of mutations in human imm... | |
| 1997 | W Keulen, N K Back, A van Wijk, Charles A B Boucher, Ben Berkhout | Initial appearance of the 184Ile vari... | |
| 1997 | Erik De Clercq | In search of a selective antiviral ch... | |
| 1997 | Zucai Suo, Kenneth A Johnson | RNA secondary structure switching dur... | |
| 1997 | Jan Balzarini, H Pelemans, G Riess, M Roesner, I Winkler, Erik De Clercq, Jörg-Peter Kleim | Zidovudine-resistant human immunodefi... | |
| 1997 | Zucai Suo, Kenneth A Johnson | Effect of RNA secondary structure on ... | |
| 1997 | A De Antoni, A Foli, J Lisziewicz, F Lori | Mutations in the pol gene of human im... | |
| 1997 | Ashwini S Kamath-Loeb, A Hizi, Hironori Kasai, Lawrence A Loeb | Incorporation of the guanosine tripho... | |
| 1997 | M D Powell, M Ghosh, P S Jacques, K J Howard, Stuart F J Le Grice, J G Levin | Alanine-scanning mutations in the "pr... | |
| 1997 | R M Esnouf, David I Stuart, Erik De Clercq, E Schwartz, Jan Balzarini | Models which explain the inhibition o... | |
| 1997 | Jörg-Peter Kleim, I Winkler, M Rösner, R Kirsch, H Rübsamen-Waigmann, A Paessens, G Riess | In vitro selection for different muta... | |
| 1997 | H Hara, T Fujihashi, T Sakata, A Kaji, H Kaji | Tetrahydronaphthalene lignan compound... | |
| 1996 | E.J. Arts, J P Marois, Z Gu, Stuart F J Le Grice, Mark A. Wainberg | Effects of 3'-deoxynucleoside 5'-trip... | |
| 1996 | CF Perno, Emanuela Balestra, Stefano Aquaro, S Panti, A Cenci, G Lazzarino, B Tavazzi, D Di Pierro, Jan Balzarini, R Calio | Potent inhibition of human immunodefi... | |
| 1996 | G Tachedjian, J Mellors, H Bazmi, C Birch, J Mills | Zidovudine resistance is suppressed b... | |
| 1996 | D L Winslow, S Garber, C Reid, H Scarnati, D Baker, M M Rayner, E D Anton | Selection conditions affect the evolu... | |
| 1996 | N K Back, Monique Nijhuis, W Keulen, Charles A B Boucher, B O Oude Essink, A B van Kuilenburg, A H van Gennip, Ben Berkhout | Reduced replication of 3TC-resistant ... | |
| 1996 | Dominique Arion, Ronald S Fletcher, G Borkow, María-José Camarasa, Jan Balzarini, G I Dmitrienko, Michael A. Parniak | Differences in the inhibition of huma... | |
| 1996 | Yudong Quan, Z Gu, Xincang Li, Zhongjie Li, C D Morrow, Mark A. Wainberg | Endogenous reverse transcription assa... | |
| 1996 | William A Beard, Dana T Minnick, C L Wade, Rajendra Prasad, R L Won, A Kumar, Thomas A Kunkel, Samuel H Wilson | Role of the "helix clamp" in HIV-1 re... | |
| 1996 | H D Sun, S X Qiu, L Z Lin, Z Y Wang, Z W Lin, T Pengsuparp, J M Pezzuto, H H Fong, G A Cordell, N R Farnsworth | Nigranoic acid, a triterpenoid from S... | |
| 1996 | J A Esté, K De Vreese, Myriam Witvrouw, J C Schmit, A-M Vandamme, J Anné, J Desmyter, G W Henson, G Bridger, Erik De Clercq | Antiviral activity of the bicyclam de... | |
| 1996 | Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Stephen H Hughes, Edward Arnold | Structure of unliganded HIV-1 reverse... | |
| 1996 | B M Moore, Ke Li, Michael B Doughty | Deoxyadenosine-based DNA polymerase p... | |
| 1996 | L Hong, A Treharne, J A Hartsuck, S Foundling, J Tang | Crystal structures of complexes of a ... | |
| 1996 | Ronald S Fletcher, G Holleschak, Eva Nagy, Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak | Single-step purification of recombina... | |
| 1996 | Kalyan Das, Jianping Ding, Y Hsiou, Arthur D Clark, H Moereels, Luc Koymans, Koen Andries, Rudi Pauwels, Paul A J Janssen, Paul L Boyer, Patrick K Clark, Richard H Smith, Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Edward Arnold | Crystal structures of 8-Cl and 9-Cl T... | |
| 1996 | Mark A. Wainberg, William C Drosopoulos, H Salomon, M Hsu, G Borkow, M Parniak, Z Gu, Q Song, J Manne, S Islam, G Castriota, Vinayaka R Prasad | Enhanced fidelity of 3TC-selected mut... | |
| 1996 | M Evers, C Poujade, F Soler, Y Ribeill, C James, Y Lelièvre, J C Gueguen, D Reisdorf, I Morize, Rudi Pauwels, Erik De Clercq, Y Hénin, Anne Bousseau, J F Mayaux, J B Le Pecq, N Dereu | Betulinic acid derivatives: a new cla... | |
| 1996 | Edward Arnold, Kalyan Das, Jianping Ding, P N Yadav, Y Hsiou, Paul L Boyer, Stephen H Hughes | Targeting HIV reverse transcriptase f... | |
| 1996 | R A Spence, Karen S Anderson, Kenneth A Johnson | HIV-1 reverse transcriptase resistanc... | |
| 1996 | Neerja Kaushik, N Rege, P N Yadav, Stefan G Sarafianos, Mukund J Modak, V N Pandey | Biochemical analysis of catalytically... | |
| 1996 | Z Gu, Xincang Li, Yudong Quan, Michael A. Parniak, Mark A. Wainberg | Studies of neutralizing monoclonal an... | |
| 1996 | Mark A. Wainberg, M Hsu, Z Gu, G Borkow, Michael A. Parniak | Effectiveness of 3TC in HIV clinical ... | |
| 1996 | Baek Kim, T R Hathaway, Lawrence A Loeb | Human immunodeficiency virus reverse ... | |
| 1996 | Mark A. Wainberg, L Lewis, H Salomon, Z Gu, A Keller, Nick Cammack, J Goldsmith, J Church, Bonnie Spira, S Wheeler, P Pizzo | Resistance to (-)-2',3'-dideoxy-3'-th... | |
| 1996 | T Pengsuparp, M Serit, Stephen H Hughes, D D Soejarto, J M Pezzuto | Specific inhibition of human immunode... | |
| 1996 | Erik De Clercq | Chemotherapy of human immunodeficienc... | |
| 1996 | Jan Balzarini, W G Brouwer, D C Dao, E M Osika, Erik De Clercq | Identification of novel thiocarboxani... | |
| 1996 | J E Wilson, A Aulabaugh, B Caligan, S McPherson, J K Wakefield, S Jablonski, C D Morrow, J E Reardon, Phillip A Furman | Human immunodeficiency virus type-1 r... | |
| 1996 | Xincang Li, Yudong Quan, E.J. Arts, Zhongjie Li, Bradley D Preston, H de Rocquigny, Bernard P Roques, J L Darlix, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg | Human immunodeficiency virus Type 1 n... | |
| 1996 | Zhongjie Li, A Shalom, Yangxin Huang, J Mak, E Arts, Mark A. Wainberg, Lawrence Kleiman | Multiple forms of tRNA(Lys3) in HIV-1. | |
| 1996 | D J Hooker, G Tachedjian, A E Solomon, A D Gurusinghe, S Land, C Birch, J L Anderson, B M Roy, Edward Arnold, N J Deacon | An in vivo mutation from leucine to t... | |
| 1996 | Jörg-Peter Kleim, M Rösner, I Winkler, A Paessens, R Kirsch, Y Hsiou, Edward Arnold, G Riess | Selective pressure of a quinoxaline n... | |
| 1996 | R A Olmsted, D E Slade, L A Kopta, S M Poppe, T J Poel, S W Newport, K B Rank, C Biles, R A Morge, T J Dueweke, Y Yagi, D L Romero, R C Thomas, S K Sharma, W G Tarpley | (Alkylamino) piperidine bis(heteroary... | |
| 1996 | Andrew L Hopkins, Jingshan Ren, R M Esnouf, B E Willcox, E Yvonne Jones, C Ross, T Miyasaka, R T Walker, Hiromichi Tanaka, David K Stammers, David I Stuart | Complexes of HIV-1 reverse transcript... | |
| 1996 | M G Davis, J E Wilson, N A VanDraanen, W H Miller, George A Freeman, S M Daluge, F L Boyd, A E Aulabaugh, George R Painter, Lawrence R Boone | DNA polymerase activity of hepatitis ... | |
| 1996 | Olga I Lavrik, Rajendra Prasad, William A Beard, I V Safronov, M I Dobrikov, Deepak K Srivastava, G V Shishkin, T G Wood, Samuel H Wilson | dNTP binding to HIV-1 reverse transcr... | |
| 1996 | G Yang, Q Song, M Charles, William C Drosopoulos, Edward Arnold, Vinayaka R Prasad | Use of chimeric human immunodeficienc... | |
| 1996 | William C Drosopoulos, Vinayaka R Prasad | Increased polymerase fidelity of E89G... | |
| 1996 | V N Pandey, Neerja Kaushik, N Rege, Stefan G Sarafianos, P N Yadav, Mukund J Modak | Role of methionine 184 of human immun... | |
| 1996 | H Jonckheere, K De Vreese, Zeger Debyser, J Vandekerckhove, Jan Balzarini, J Desmyter, Erik De Clercq, J Anné | A two plasmid co-expression system in... | |
| 1996 | Jan Balzarini, O Wedgwood, J Kruining, H Pelemans, R Heijtink, Erik De Clercq, Christopher McGuigan | Anti-HIV and anti-HBV activity and re... | |
| 1996 | Jan Balzarini, H Pelemans, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson | Marked inhibitory activity of non-nuc... | |
| 1996 | Zeger Debyser, Erik De Clercq | Chemical crosslinking of the subunits... | |
| 1996 | P Richard Harrigan, I Kinghorn, Stuart Bloor, S D Kemp, I Nájera, A Kohli, Brendan A Larder | Significance of amino acid variation ... | |
| 1996 | D Bellarosa, G Antonelli, F Bambacioni, D Giannotti, G Viti, R Nannicini, A Giachetti, F Dianzani, Myriam Witvrouw, Rudi Pauwels, J Desmyter, Erik De Clercq | New arylpyrido-diazepine and -thiodia... | |
| 1996 | A K Iversen, R W Shafer, K Wehrly, M A Winters, J I Mullins, B Chesebro, T C Merigan | Multidrug-resistant human immunodefic... | |
| 1996 | Michael J Lutz, H A Held, M Hottiger, Ulrich Hübscher, Steven A Benner | Differential discrimination of DNA po... | |
| 1996 | Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak | The K65R mutation confers increased D... | RT,Cloned or native,Full length or truncated,Extension from RNA primer,All properties |
| 1996 | J M Cherrington, A S Mulato, M D Fuller, M S Chen | Novel mutation (K70E) in human immuno... | |
| 1996 | M Hottiger, Ulrich Hübscher | Human Immunodeficiency Virus type 1 r... | |
| 1996 | Charles A B Boucher, W Keulen, T van Bommel, Monique Nijhuis, D de Jong, M D de Jong, P Schipper, N K Back | Human immunodeficiency virus type 1 d... | |
| 1996 | L M Mansky | Forward mutation rate of human immuno... | |
| 1996 | S Ingate, Erik De Clercq, Jan Balzarini, María-José Camarasa | Novel L-lyxo and 5'-deoxy-5'-modified... | |
| 1996 | Rudi Pauwels, Erik De Clercq | Development of vaginal microbicides f... | |
| 1996 | J M Cherrington, M D Fuller, A S Mulato, S J Allen, S C Kunder, M A Ussery, Z Lesnikowski, Raymond F Schinazi, J P Sommadossi, M S Chen | Comparative kinetic analyses of inter... | |
| 1996 | Dominique Arion, R Harada, Xincang Li, Mark A. Wainberg, Michael A. Parniak | HIV-1 reverse transcriptase shows no ... | |
| 1996 | J Ji, N J Clegg, K R Peterson, A L Jackson, C D Laird, Lawrence A Loeb | In vitro expansion of GGC:GCC repeats... | |
| 1996 | A Foli, K M Sogocio, B Anderson, M Kavlick, M W Saville, Mark A. Wainberg, Z Gu, J M Cherrington, Hiroyuki Mitsuya, R Yarchoan | In vitro selection and molecular char... | |
| 1996 | F Soler, C Poujade, M Evers, J C Carry, Y Hénin, Anne Bousseau, T Huet, Rudi Pauwels, Erik De Clercq, J F Mayaux, J B Le Pecq, N Dereu | Betulinic acid derivatives: a new cla... | |
| 1996 | Yangxin Huang, A Shalom, Zhongjie Li, Jiong Wang, J Mak, Mark A. Wainberg, Lawrence Kleiman | Effects of modifying the tRNA(3Lys) a... | |
| 1996 | A M Martín-Hernández, Esteban Domingo, L Menéndez-Arias | Human immunodeficiency virus type 1 r... | |
| 1996 | Stefan G Sarafianos, U Kortz, M T Pope, Mukund J Modak | Mechanism of polyoxometalate-mediated... | |
| 1995 | Jan Balzarini, María-Jesús Pérez-Pérez, S Vélazquez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson | Suppression of the breakthrough of hu... | |
| 1995 | B M Wöhrl, C Tantillo, Edward Arnold, Stuart F J Le Grice | An expanded model of replicating huma... | |
| 1995 | Edward Arnold, Jianping Ding, Stephen H Hughes, Z Hostomsky | Structures of DNA and RNA polymerases... | |
| 1995 | Y Törnevik, B Ullman, Jan Balzarini, B Wahren, Staffan Eriksson | Cytotoxicity of 3'-azido-3'-deoxythym... | |
| 1995 | Katarzyna Bebenek, Thomas A Kunkel | Analyzing fidelity of DNA polymerases. | Frameshift Error Rate,Overall Error Rate,All properties |
| 1995 | Erik De Clercq, Jan Balzarini | Knocking out human immunodeficiency v... | |
| 1995 | Jan Balzarini, W G Brouwer, E E Felauer, Erik De Clercq, Anna Karlsson | Activity of various thiocarboxanilide... | |
| 1995 | S D Young, S F Britcher, L O Tran, L S Payne, W C Lumma, T A Lyle, J R Huff, P S Anderson, David B Olsen, Steven S Carroll | L-743, 726 (DMP-266): a novel, highly... | |
| 1995 | Haijiang Zhang, L Vrang, K Bäckbro, P Lind, Christer Sahlberg, Torsten Unge, Bo Oberg | Inhibition of human immunodeficiency ... | |
| 1995 | John W Mellors, Holly Z Bazmi, Raymond F Schinazi, B M Roy, Y Hsiou, Edward Arnold, J Weir, D L Mayers | Novel mutations in reverse transcript... | |
| 1995 | R A Spence, W M Kati, Karen S Anderson, Kenneth A Johnson | Mechanism of inhibition of HIV-1 reve... | |
| 1995 | Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak | Site-directed mutagenesis of arginine... | |
| 1995 | Jan Balzarini | Novel concepts in the treatment of hu... | |
| 1995 | M Sala, S Wain-Hobson, F Schaeffer | Human immunodeficiency virus type 1 r... | |
| 1995 | M Jaju, William A Beard, Samuel H Wilson | Human immunodeficiency virus type 1 r... | |
| 1995 | Robert W Buckheit, V Fliakas-Boltz, S Yeagy-Bargo, O Weislow, D L Mayers, Paul L Boyer, Stephen H Hughes, B C Pan, S H Chu, J P Bader | Resistance to 1-[(2-hydroxyethoxy)met... | |
| 1995 | M Hottiger, K Gramatikoff, O Georgiev, C Chaponnier, W Schaffner, Ulrich Hübscher | The large subunit of HIV-1 reverse tr... | |
| 1995 | N M Gray, C L Marr, C R Penn, J M Cameron, R C Bethell | The intracellular phosphorylation of ... | |
| 1995 | M I Anazodo, H Salomon, A D Friesen, Mark A. Wainberg, J A Wright | Antiviral activity and protection of ... | |
| 1995 | J Horlacher, M Hottiger, Vladimir N Podust, Ulrich Hübscher, Steven A Benner | Recognition by viral and cellular DNA... | |
| 1995 | Jingshan Ren, R Esnouf, A Hopkins, C Ross, Y Jones, D Stammers, David I Stuart | The structure of HIV-1 reverse transc... | |
| 1995 | Jianping Ding, Kalyan Das, C Tantillo, Weiming Zhang, Arthur D Clark, S Jessen, Xiaoqing Lu, Y Hsiou, A Jacobo-Molina, Koen Andries | Structure of HIV-1 reverse transcript... | |
| 1995 | T Shirasaka, M F Kavlick, Takayuki Ueno, W Y Gao, E Kojima, M L Alcaide, S Chokekijchai, B M Roy, Edward Arnold, R Yarchoan | Emergence of human immunodeficiency v... | |
| 1995 | Mark A. Wainberg, Z Gu, H Salomon, E.J. Arts, Lawrence Kleiman, Michael A. Parniak, N Morin | [Molecular basis and clinical signifi... | |
| 1995 | Hongxing Zhang, Yang Zhang, T Spicer, D Henrard, B J Poiesz | Nascent human immunodeficiency virus ... | |
| 1995 | Ronald S Fletcher, K Syed, S Mithani, G I Dmitrienko, Michael A. Parniak | Carboxanilide derivative non-nucleosi... | |
| 1995 | Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari | Stereospecificity of human DNA polyme... | |
| 1995 | P N Yadav, J S Yadav, Mukund J Modak | Nucleoside drug resistance in HIV-1 r... | |
| 1995 | Jan Balzarini, M Weeger, María-José Camarasa, Erik De Clercq, K Uberla | Sensitivity/resistance profile of a s... | |
| 1995 | M Ghosh, K J Howard, Craig E Cameron, Stephen J Benkovic, Stephen H Hughes, Stuart F J Le Grice | Truncating alpha-helix E' of p66 huma... | |
| 1995 | Jingshan Ren, R Esnouf, E Garman, D Somers, C Ross, I Kirby, J Keeling, G Darby, Y Jones, David I Stuart | High resolution structures of HIV-1 R... | |
| 1995 | Z Gu, Yudong Quan, Zhongjie Li, E.J. Arts, Mark A. Wainberg | Effects of non-nucleoside inhibitors ... | |
| 1995 | Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak | Glutamine 151 participates in the sub... | |
| 1995 | Baek Kim, Lawrence A Loeb | A screen in Escherichia coli for nucl... | |
| 1995 | K Rittinger, G Divita, R S Goody | Human immunodeficiency virus reverse ... | |
| 1995 | M I Anazodo, Mark A. Wainberg, A D Friesen, J A Wright | Sequence-specific inhibition of gene ... | |
| 1995 | Ronald S Fletcher, Dominique Arion, G Borkow, Mark A. Wainberg, G I Dmitrienko, Michael A. Parniak | Synergistic inhibition of HIV-1 rever... | |
| 1995 | Takayuki Ueno, T Shirasaka, Hiroyuki Mitsuya | Enzymatic characterization of human i... | |
| 1995 | Silvio Spadari, Giovanni Maga, A Verri, A Bendiscioli, L Tondelli, M Capobianco, F Colonna, A Garbesi, Federico Focher | Lack of stereospecificity of some cel... | |
| 1995 | R J Germinario, T DeSantis, Mark A. Wainberg | Insulin-like growth factor 1 and insu... | |
| 1995 | D W Rodgers, S J Gamblin, B A Harris, S Ray, J S Culp, B Hellmig, D J Woolf, C Debouck, S C Harrison | The structure of unliganded reverse t... | |
| 1995 | Marilyn B Kroeger Smith, C A Rouzer, L A Taneyhill, N A Smith, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, H Moereels, Luc Koymans, Edward Arnold | Molecular modeling studies of HIV-1 r... | |
| 1995 | Matthias Götte, S Fackler, T Hermann, E Perola, Luciano Cellai, H J Gross, Stuart F J Le Grice, H Heumann | HIV-1 reverse transcriptase-associate... | |
| 1995 | Jörg-Peter Kleim, R Bender, R Kirsch, C Meichsner, A Paessens, M Rösner, H Rübsamen-Waigmann, R Kaiser, M Wichers, K E Schneweis | Preclinical evaluation of HBY 097, a ... | |
| 1995 | Katarzyna Bebenek, William A Beard, J R Casas-Finet, H R Kim, Thomas A Darden, Samuel H Wilson, Thomas A Kunkel | Reduced frameshift fidelity and proce... | |
| 1995 | R R Vyas, A K Basu | DNA polymerase action on an oligonucl... | |
| 1995 | R Esnouf, Jingshan Ren, C Ross, Y Jones, D Stammers, David I Stuart | Mechanism of inhibition of HIV-1 reve... | |
| 1995 | Jan Balzarini, Masanori Baba, Erik De Clercq | Differential activities of 1-[(2-hydr... | |
| 1995 | Sonsoles Velázquez, R Alvarez, Ana San-Félix, M L Jimeno, Erik De Clercq, Jan Balzarini, María-José Camarasa | Synthesis and anti-HIV activity of [A... | |
| 1995 | G Tachedjian, D J Hooker, A D Gurusinghe, H Bazmi, N J Deacon, J Mellors, C Birch, J Mills | Characterisation of foscarnet-resista... | |
| 1995 | Baek Kim, Lawrence A Loeb | Human immunodeficiency virus reverse ... | |
| 1995 | L M Mansky, H M Temin | Lower in vivo mutation rate of human ... | |
| 1995 | Rob Schuurman, Monique Nijhuis, R van Leeuwen, P Schipper, D de Jong, P Collis, Sven A Danner, J Mulder, C Loveday, C Christopherson | Rapid changes in human immunodeficien... | |
| 1995 | Brendan A Larder, S D Kemp, P Richard Harrigan | Potential mechanism for sustained ant... | |
| 1995 | Robert W Buckheit, T L Kinjerski, V Fliakas-Boltz, J D Russell, T L Stup, L A Pallansch, W G Brouwer, D C Dao, W A Harrison, R J Schultz | Structure-activity and cross-resistan... | |
| 1995 | Z Gu, E.J. Arts, Michael A. Parniak, Mark A. Wainberg | Mutated K65R recombinant reverse tran... | |
| 1995 | E.J. Arts, Zhongjie Li, Mark A. Wainberg | Analysis of Primer Extension and the ... | |
| 1995 | Mark A. Wainberg, Z Gu | Targeting HIV reverse transcriptase i... | |
| 1995 | V McKiel, Z Gu, Mark A. Wainberg, J Hiscott | Inhibition of human immunodeficiency ... | |
| 1995 | Jianping Ding, Kalyan Das, H Moereels, Luc Koymans, Koen Andries, Paul A J Janssen, Stephen H Hughes, Edward Arnold | Structure of HIV-1 RT/TIBO R 86183 co... | |
| 1995 | P H Patel, A Jacobo-Molina, Jianping Ding, C Tantillo, Art D Clark, R Raag, R G Nanni, Stephen H Hughes, Edward Arnold | Insights into DNA polymerization mech... | |
| 1994 | Paul L Boyer, Jianping Ding, Edward Arnold, Stephen H Hughes | Subunit specificity of mutations that... | |
| 1994 | Jan Balzarini, Jörg-Peter Kleim, G Riess, María-José Camarasa, Erik De Clercq, Anna Karlsson | Sensitivity of (138 Glu-->Lys) mutate... | |
| 1994 | S Loya, M Bakhanashvili, R Tal, Stephen H Hughes, Paul L Boyer, A Hizi | Enzymatic properties of two mutants o... | |
| 1994 | T Rubinek, S Loya, M Shaharabany, Stephen H Hughes, Patrick K Clark, A Hizi | The catalytic properties of the rever... | |
| 1994 | M A Fisher, P N Yadav, J Yadav, D Kristol, Edward Arnold, Mukund J Modak | Identification of a pharmacophore for... | |
| 1994 | Paul L Boyer, Andrea L Ferris, Patrick K Clark, J Whitmer, P Frank, C Tantillo, Edward Arnold, Stephen H Hughes | Mutational analysis of the fingers an... | |
| 1994 | C Tantillo, Jianping Ding, A Jacobo-Molina, R G Nanni, Paul L Boyer, Stephen H Hughes, Rudi Pauwels, Koen Andries, Paul A J Janssen, Edward Arnold | Locations of anti-AIDS drug binding s... | |
| 1994 | Jianping Ding, A Jacobo-Molina, C Tantillo, Xiaoqing Lu, R G Nanni, Edward Arnold | Buried surface analysis of HIV-1 reve... | |
| 1994 | Myron F Goodman, H Cai, Linda B Bloom, R Eritja | Nucleotide insertion and primer exten... | |
| 1994 | T Hermann, T Meier, Matthias Götte, H Heumann | The 'helix clamp' in HIV-1 reverse tr... | |
| 1994 | S F Lacey, Brendan A Larder | Novel mutation (V75T) in human immuno... | |
| 1994 | A-M Vandamme, Zeger Debyser, Rudi Pauwels, K De Vreese, P Goubau, M Youle, B Gazzard, P A Stoffels, G F Cauwenbergh, J Anne | Characterization of HIV-1 strains iso... | |
| 1994 | Jan Balzarini, Anna Karlsson, V V Sardana, E A Emini, María-José Camarasa, Erik De Clercq | Human immunodeficiency virus 1 (HIV-1... | |
| 1994 | G Gosselin, Raymond F Schinazi, J P Sommadossi, C Mathé, M C Bergogne, A M Aubertin, A Kirn, J L Imbach | Anti-human immunodeficiency virus act... | |
| 1994 | M H Nguyen, Raymond F Schinazi, C Shi, N M Goudgaon, P M McKenna, John W Mellors | Resistance of human immunodeficiency ... | |
| 1994 | Douglas D Richman, D Havlir, J Corbeil, D Looney, C Ignacio, S A Spector, J Sullivan, S Cheeseman, K Barringer, D Pauletti | Nevirapine resistance mutations of hu... | |
| 1994 | V W Byrnes, E A Emini, W A Schleif, J H Condra, C L Schneider, W J Long, J A Wolfgang, D J Graham, L Gotlib, A J Schlabach | Susceptibilities of human immunodefic... | |
| 1994 | I Kang, Jing-Houng Wang | Design of structure-based reverse tra... | |
| 1994 | M D Delahunty, Samuel H Wilson, R L Karpel | Studies on primer binding of HIV-1 re... | |
| 1994 | William A Beard, Samuel H Wilson | Site-directed mutagenesis of HIV reve... | |
| 1994 | J Ji, Lawrence A Loeb | Fidelity of HIV-1 reverse transcripta... | |
| 1994 | S V Doronin, M I Dobrikov, M Buckle, P Roux, H Buc, Olga I Lavrik | Affinity modification of human immuno... | |
| 1994 | P N Yadav, J S Yadav, Edward Arnold, Mukund J Modak | A computer-assisted analysis of conse... | |
| 1994 | H Pelletier, M R Sawaya, A Kumar, Samuel H Wilson, J Kraut | Structures of ternary complexes of ra... | |
| 1994 | J Ji, Jean-Sébastien Hoffmann, L Loeb | Mutagenicity and pausing of HIV rever... | |
| 1994 | M Hottiger, Vladimir N Podust, R L Thimmig, C McHenry, Ulrich Hübscher | Strand displacement activity of the h... | |
| 1994 | E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg | DNA found in human immunodeficiency v... | |
| 1994 | S J Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, A J Chirino, J M Friedman, P A Rice, Thomas A Steitz | Structure of the binding site for non... | |
| 1994 | E.J. Arts, Xincang Li, Z Gu, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg | Comparison of deoxyoligonucleotide an... | |
| 1994 | Z Gu, Q Gao, H Fang, Michael A. Parniak, Bluma G Brenner, Mark A. Wainberg | Identification of novel mutations tha... | |
| 1994 | A Okruszek, M Olesiak, Jan Balzarini | The synthesis of nucleoside 5'-O-(1,1... | |
| 1994 | M R Sawaya, H Pelletier, A Kumar, Samuel H Wilson, J Kraut | Crystal structure of rat DNA polymera... | |
| 1994 | Erik De Clercq | HIV resistance to reverse transcripta... | |
| 1994 | Erik De Clercq | How to overcome resistance of HIV-1 t... | |
| 1994 | E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg | Mature reverse transcriptase (p66/p51... | |
| 1994 | J Mak, M Jiang, Mark A. Wainberg, M L Hammarskjöld, D Rekosh, Lawrence Kleiman | Role of Pr160gag-pol in mediating the... | |
| 1994 | Z Gu, Ronald S Fletcher, E.J. Arts, Mark A. Wainberg, Michael A. Parniak | The K65R mutant reverse transcriptase... | |
| 1994 | M Smith, H Salomon, Mark A. Wainberg | Development and significance of nucle... | |
| 1994 | J Jäger, S J Smerdon, Jianhong Wang, D C Boisvert, Thomas A Steitz | Comparison of three different crystal... | |
| 1994 | Jan Balzarini, Anna Karlsson, C Meichsner, A Paessens, G Riess, Erik De Clercq, Jörg-Peter Kleim | Resistance pattern of human immunodef... | |
| 1994 | H Jonckheere, J M Taymans, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, J Desmyter, Erik De Clercq, J Anné | Resistance of HIV-1 reverse transcrip... | |
| 1994 | Paul L Boyer, C Tantillo, A Jacobo-Molina, R G Nanni, Jianping Ding, Edward Arnold, Stephen H Hughes | Sensitivity of wild-type human immuno... | |
| 1994 | L Mercure, B J Brenner, D Phaneuf, C Tsoukas, Mark A. Wainberg | Effect of 3'-azido-3'-deoxythymidine ... | |
| 1994 | Rudi Pauwels, Koen Andries, Zeger Debyser, Michael J Kukla, Dominique Schols, H J Breslin, R Woestenborghs, J Desmyter, M A Janssen, Erik De Clercq | New tetrahydroimidazo[4,5,1-jk][1,4]-... | |
| 1994 | Erik De Clercq | New developments in the chemotherapy ... | |
| 1994 | Masanori Baba, S Shigeta, S Yuasa, H Takashima, K Sekiya, M Ubasawa, Hiromichi Tanaka, T Miyasaka, R T Walker, Erik De Clercq | Preclinical evaluation of MKC-442, a ... | |
| 1994 | Torsten Unge, S Knight, R Bhikhabhai, S Lövgren, Z Dauter, K Wilson, B Strandberg | 2.2 A resolution structure of the ami... | |
| 1994 | P S Jacques, B M Wöhrl, M Ottmann, J L Darlix, Stuart F J Le Grice | Mutating the "primer grip" of p66 HIV... | |
| 1994 | S Zinnen, J C Hsieh, P Modrich | Misincorporation and mispaired primer... | |
| 1993 | Mark A. Wainberg, H Salomon, Bonnie Spira, L Mercure, J Wainberg, K Nagai, Z Bentwich, J Montaner | HIV resistance to anti-viral drugs. | |
| 1993 | M S Saag, E A Emini, O L Laskin, J Douglas, W I Lapidus, W A Schleif, R J Whitley, C Hildebrand, V W Byrnes, John C Kappes | A short-term clinical evaluation of L... | |
| 1993 | S P Becerra, A Kumar, Samuel H Wilson | Expression of polypeptides of human i... | |
| 1993 | Katarzyna Bebenek, J Abbotts, Samuel H Wilson, Thomas A Kunkel | Error-prone polymerization by HIV-1 r... | |
| 1993 | Jörg-Peter Kleim, R Bender, U M Billhardt, C Meichsner, G Riess, M Rösner, I Winkler, A Paessens | Activity of a novel quinoxaline deriv... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, Erik De Clercq | Knocking-out concentrations of HIV-1-... | |
| 1993 | G Maass, U Immendoerfer, B Koenig, U Leser, B Mueller, R Goody, E Pfaff | Viral resistance to the thiazolo-iso-... | |
| 1993 | Zeger Debyser, K De Vreese, P P Knops-Gerrits, V Baekelandt, R Bhikhabhai, B Strandberg, Rudi Pauwels, J Anné, J Desmyter, Erik De Clercq | Kinetics of different human immunodef... | |
| 1993 | Jan Balzarini, Anna Karlsson, Erik De Clercq | Human immunodeficiency virus type 1 d... | |
| 1993 | Myron F Goodman, S Creighton, Linda B Bloom, John Petruska | Biochemical basis of DNA replication ... | |
| 1993 | Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors | Characterization of human immunodefic... | |
| 1993 | John W Mellors, G J Im, Enzo Tramontano, S R Winkler, D J Medina, Ginger E Dutschman, Holly Z Bazmi, G Piras, C J Gonzalez, Yung-Chi Cheng | A single conservative amino acid subs... | |
| 1993 | Kristin A Eckert, Thomas A Kunkel | Fidelity of DNA synthesis catalyzed b... | Cloned or native,Full length or truncated,Specific Activity,3-5' exo,Nucleotide Substitution Rate,All properties |
| 1993 | Svetlana N Khodyreva, Vladimir N Podust, D S Sergeev, E M Ivanova, E I Frolova, A A Koshkin, T S Godovikova, V F Zarytova, Miria Ricchetti, Olga I Lavrik | Comparison of interactions of 5'-deri... | |
| 1993 | J L Martin, J E Wilson, R L Haynes, Phillip A Furman | Mechanism of resistance of human immu... | |
| 1993 | Robert W Sobol, W L Fisher, N L Reichenbach, A Kumar, William A Beard, Samuel H Wilson, R Charubala, W Pfleiderer, R J Suhadolnik | HIV-1 reverse transcriptase: inhibiti... | |
| 1993 | Erik De Clercq | HIV-1-specific RT inhibitors: highly ... | |
| 1993 | William A Beard, Samuel H Wilson | Kinetic analysis of template.primer i... | |
| 1993 | Paul L Boyer, M J Currens, James B McMahon, M R Boyd, Stephen H Hughes | Analysis of nonnucleoside drug-resist... | |
| 1993 | A Kumar, H R Kim, Robert W Sobol, S P Becerra, B J Lee, D L Hatfield, R J Suhadolnik, Samuel H Wilson | Mapping of nucleic acid binding in pr... | |
| 1993 | H Cai, Linda B Bloom, R Eritja, Myron F Goodman | Kinetics of deoxyribonucleotide inser... | |
| 1993 | J Abbotts, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson | Mechanism of HIV-1 reverse transcript... | |
| 1993 | R Goel, William A Beard, A Kumar, J R Casas-Finet, M P Strub, S J Stahl, M S Lewis, Katarzyna Bebenek, S P Becerra, Thomas A Kunkel | Structure/function studies of HIV-1(1... | |
| 1993 | W Y Gao, A Cara, R C Gallo, F Lori | Low levels of deoxynucleotides in per... | |
| 1993 | Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg | The same mutation that encodes low-le... | |
| 1993 | C T Wang, Yongqing Zhang, J McDermott, E Barklis | Conditional infectivity of a human im... | |
| 1993 | J C Hsieh, S Zinnen, P Modrich | Kinetic mechanism of the DNA-dependen... | |
| 1993 | Thomas A Steitz, S Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, J M Friedman, Lorena S Beese, P A Rice | Two DNA polymerases: HIV reverse tran... | |
| 1993 | A Jacobo-Molina, Jianping Ding, R G Nanni, Arthur D Clark, Xiaoqing Lu, C Tantillo, R L Williams, G Kamer, Andrea L Ferris, Patrick K Clark | Crystal structure of human immunodefi... | |
| 1993 | Johan Neyts, F Stals, C Bruggeman, Erik De Clercq | Activity of the anti-HIV agent 9-(2-p... | |
| 1993 | M S Chen, R T Suttmann, E Papp, P D Cannon, M J McRoberts, C Bach, William C Copeland, Teresa S-F Wang | Selective action of 4'-azidothymidine... | |
| 1993 | S St Luce, E Arts, R Geleziunas, S Bour, Mark A. Wainberg | Infection of human monocyte-derived m... | |
| 1993 | Mark A. Wainberg, Z Gu, Q Gao, E Arts, R Geleziunas, S Bour, R Beaulieu, C Tsoukas, J Singer, J Montaner | Clinical correlates and molecular bas... | |
| 1993 | S Kawa, A Kumar, J S Smith, S P Becerra, William A Beard, Samuel H Wilson, E B Thompson | Expression and purification of the HI... | |
| 1993 | R Sousa, Y J Chung, J P Rose, B C Wang | Crystal structure of bacteriophage T7... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, L Vrang, J Walbers, Haijiang Zhang, Bo Oberg, A-M Vandamme, María-José Camarasa, Erik De Clercq | HIV-1-specific reverse transcriptase ... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, W G Tarpley, Erik De Clercq | Treatment of human immunodeficiency v... | |
| 1993 | Jan Balzarini, Sonsoles Velazquez, A San-Felix, Anna Karlsson, M J Perez-Perez, María-José Camarasa, Erik De Clercq | Human immunodeficiency virus type 1-s... | |
| 1993 | Jan Balzarini, Anna Karlsson, A-M Vandamme, María-Jesús Pérez-Pérez, Haijiang Zhang, L Vrang, Bo Oberg, K Bäckbro, Torsten Unge, Ana San-Félix | Human immunodeficiency virus type 1 (... | |
| 1993 | T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley | A mutation in reverse transcriptase o... | |
| 1993 | M Tisdale, S D Kemp, N R Parry, Brendan A Larder | Rapid in vitro selection of human imm... | |
| 1993 | A Hizi, R Tal, M Shaharabany, M J Currens, M R Boyd, Stephen H Hughes, James B McMahon | Specific inhibition of the reverse tr... | |
| 1993 | D Chattopadhyay, B C Finzel, S H Munson, D B Evans, S K Sharma, N A Strakalaitus, D P Brunner, F M Eckenrode, Z Dauter, C Betzel, H M Einspahr | Crystallographic analyses of an activ... | |
| 1993 | G T Tan, A Wickramasinghe, S Verma, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan | Sulfonic acid polymers are potent inh... | |
| 1993 | Xincang Li, E Amandoron, Mark A. Wainberg, Michael A. Parniak | Generation and characterization of mu... | |
| 1993 | Erik De Clercq | Antiviral agents: characteristic acti... | |
| 1993 | R L Thimmig, Charles S McHenry | Human immunodeficiency virus reverse ... | |
| 1992 | M Bakhanashvili, A Hizi | Fidelity of the reverse transcriptase... | RT,3-5' exo,All properties |
| 1992 | J A Coates, Nick Cammack, H J Jenkinson, A J Jowett, M I Jowett, B A Pearson, C R Penn, P L Rouse, K C Viner, J M Cameron | (-)-2'-deoxy-3'-thiacytidine is a pot... | |
| 1992 | Zeger Debyser, Rudi Pauwels, Koen Andries, Erik De Clercq | Specific HIV-1 reverse transcriptase ... | |
| 1992 | Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Y Engelborghs, Paul A J Janssen, Erik De Clercq | Allosteric inhibition of human immuno... | |
| 1992 | Erik De Clercq | New perspectives for the chemotherapy... | |
| 1992 | Erik De Clercq | HIV inhibitors targeted at the revers... | |
| 1992 | L A Kohlstaedt, Jianhong Wang, J M Friedman, P A Rice, Thomas A Steitz | Crystal structure at 3.5 A resolution... | |
| 1992 | K De Vreese, Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, J Desmyter, Erik De Clercq, J Anné | Resistance of human immunodeficiency ... | |
| 1992 | Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, Masanori Baba, J Desmyter, Erik De Clercq | Kinetics of inhibition of endogenous ... | |
| 1992 | M M Huang, Norman Arnheim, Myron F Goodman | Extension of base mispairs by Taq DNA... | |
| 1992 | V Gopalakrishnan, J A Peliska, Stephen J Benkovic | Human immunodeficiency virus type 1 r... | RT,Terminal Transferase,RNase H,All properties |
| 1992 | J P Ji, Lawrence A Loeb | Fidelity of HIV-1 reverse transcripta... | |
| 1992 | V V Sardana, E A Emini, L Gotlib, D J Graham, D W Lineberger, W J Long, A J Schlabach, J A Wolfgang, J H Condra | Functional analysis of HIV-1 reverse ... | |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Dominique Schols, CF Perno, A-M Vandamme, María-José Camarasa, Erik De Clercq | 2',5'-Bis-O-(tert-butyldimethylsilyl)... | |
| 1992 | Alberto Bergamini, CF Perno, Jan Balzarini, M Capozzi, Luciana Marinelli, G Milanese, C D Pesce, R Calió, G Rocchi | Selective inhibition of HIV replicati... | |
| 1992 | I I Fedorov, E M Kazmina, N A Novicov, Galina V Gurskaya, A V Bochkarev, M V Jasko, L S Victorova, M K Kukhanova, Jan Balzarini, Erik De Clercq | 3'-C-branched 2'-deoxy-5-methyluridin... | |
| 1992 | N Yamamoto, Dominique Schols, Erik De Clercq, Zeger Debyser, Rudi Pauwels, Jan Balzarini, H Nakashima, Masanori Baba, M Hosoya, Robert Snoeck | Mechanism of anti-human immunodeficie... | |
| 1992 | J A Peliska, Stephen J Benkovic | Mechanism of DNA strand transfer reac... | |
| 1992 | A Basu, K K Ahluwalia, S Basu, Mukund J Modak | Identification of the primer binding ... | |
| 1992 | Tsuyoshi Yamaguchi, Shunji Izuta, Motoshi Suzuki, Shonen Yoshida, Akio Matsukage, Mineo Saneyoshi | Inhibitory effects of 2'-deoxy-5-styr... | |
| 1992 | A Basu, S Basu, Mukund J Modak | Structure-activity analyses of HIV-1 ... | |
| 1992 | J A Coates, Nick Cammack, H J Jenkinson, I M Mutton, B A Pearson, R Storer, J M Cameron, C R Penn | The separated enantiomers of 2'-deoxy... | |
| 1992 | L A Kohlstaedt, Thomas A Steitz | Reverse transcriptase of human immuno... | |
| 1992 | J C Boyer, Katarzyna Bebenek, Thomas A Kunkel | Unequal human immunodeficiency virus ... | |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, I C Bathurst, P J Barr, Erik De Clercq | Kinetics of inhibition of human immun... | |
| 1992 | Shunji Izuta, N Shimada, Masatoshi Kitagawa, Motoshi Suzuki, K Kojima, Shonen Yoshida | Inhibitory effects of triphosphate de... | |
| 1992 | J J DeStefano, R G Buiser, L M Mallaber, P J Fay, Robert A Bambara | Parameters that influence processive ... | RT,Full length or truncated,Specific Activity,Processivity,Molecular Weight,RNase H,All properties |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velazquez, María-José Camarasa, Erik De Clercq | [2',5'-Bis-O-(tert-butyldimethylsilyl... | |
| 1992 | Brendan A Larder | 3'-Azido-3'-deoxythymidine resistance... | |
| 1992 | J Abbotts, Samuel H Wilson | Inhibitors of HIV-1 reverse transcrip... | |
| 1992 | Z Hostomsky, Z Hostomska, T B Fu, J Taylor | Reverse transcriptase of human immuno... | |
| 1992 | S F Lacey, J E Reardon, E S Furfine, Thomas A Kunkel, Katarzyna Bebenek, Kristin A Eckert, S D Kemp, Brendan A Larder | Biochemical studies on the reverse tr... | |
| 1992 | Zeger Debyser, K De Vreese, Rudi Pauwels, N Yamamoto, J Anné, Erik De Clercq, J Desmyter | Differential inhibitory effects of TI... | |
| 1992 | P Kellam, Charles A B Boucher, Brendan A Larder | Fifth mutation in human immunodeficie... | |
| 1992 | Q Gao, Z X Gu, Michael A. Parniak, X G Li, Mark A. Wainberg | In vitro selection of variants of hum... | |
| 1992 | M B Vasudevachari, C Battista, H C Lane, M C Psallidopoulos, B Zhao, J Cook, J R Palmer, D L Romero, W G Tarpley, N P Salzman | Prevention of the spread of HIV-1 inf... | |
| 1992 | John W Mellors, Ginger E Dutschman, G J Im, Enzo Tramontano, S R Winkler, Yung-Chi Cheng | In vitro selection and molecular char... | |
| 1992 | Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg | Novel mutation in the human immunodef... | |
| 1992 | C S Crumpacker | Mechanism of action of foscarnet agai... | |
| 1992 | W M Kati, Kenneth A Johnson, L F Jerva, Karen S Anderson | Mechanism and fidelity of HIV reverse... | |
| 1992 | G T Tan, J F Miller, A D Kinghorn, Stephen H Hughes, J M Pezzuto | HIV-1 and HIV-2 reverse transcriptase... | |
| 1992 | S Loya, R Tal, Stephen H Hughes, A Hizi | The effects of cysteine mutations on ... | |
| 1992 | A Hosmalin, S Kumar, D Barnd, R Houghten, G E Smith, Stephen H Hughes, J A Berzofsky | Immunization with soluble protein-pul... | |
| 1992 | D L Mayers, F E McCutchan, E E Sanders-Buell, L I Merritt, S Dilworth, A K Fowler, C A Marks, N M Ruiz, Douglas D Richman, C R Roberts | Characterization of HIV isolates aris... | |
| 1992 | Edward Arnold, A Jacobo-Molina, R G Nanni, R L Williams, Xiaoqing Lu, Jianping Ding, Art D Clark, A Zhang, Andrea L Ferris, Patrick K Clark | Structure of HIV-1 reverse transcript... | |
| 1992 | Hong Yu, Myron F Goodman | Comparison of HIV-1 and avian myelobl... | |
| 1992 | Paul L Boyer, Andrea L Ferris, Stephen H Hughes | Mutational analysis of the fingers do... | |
| 1992 | G T Tan, A Wickramasinghe, S Verma, R Singh, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan | Potential anti-AIDS naphthalenesulfon... | |
| 1992 | William C Copeland, M S Chen, Teresa S-F Wang | Human DNA polymerases alpha and beta ... | |
| 1992 | J E Reardon | Human immunodeficiency virus reverse ... | |
| 1992 | R L Mitina, S V Doronin, M I Dobrikov, D R Tabatadze, A S Levina, Olga I Lavrik | Human immunodeficiency virus type 1 r... | |
| 1992 | L Ding, Jan Balzarini, Dominique Schols, B Meunier, Erik De Clercq | Anti-human immunodeficiency virus eff... | |
| 1992 | F Boulerice, R Geleziunas, S Bour, H L Li, M D'Addario, A Roulston, J Hiscott, Mark A. Wainberg | Differential susceptibilities of U-93... | |
| 1992 | M Jiang, J Mak, Mark A. Wainberg, Michael A. Parniak, E Cohen, Lawrence Kleiman | Variable tRNA content in HIV-1IIIB. | |
| 1992 | Mark A. Wainberg, R G Margolese | Strategies in the treatment of AIDS a... | |
| 1991 | J E Reardon, E S Furfine, N Cheng | Human immunodeficiency virus reverse ... | |
| 1991 | A DeVico, R C Montelaro, R C Gallo, M G Sarngadharan | Purification and partial characteriza... | RT,Full length or truncated,3-5' exo,Nucleotide Substitution Rate,RNase H,All properties |
| 1991 | F Boulerice, X G Li, A Lvovich, Mark A. Wainberg | Recovery of infectious human immunode... | |
| 1991 | R S Goody, B Müller, Tobias Restle | Factors contributing to the inhibitio... | |
| 1991 | D Richman, C K Shih, I Lowy, J Rose, P Prodanovich, S Goff, J Griffin | Human immunodeficiency virus type 1 m... | |
| 1991 | Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, R T Walker, S Mori | Highly potent and selective inhibitio... | |
| 1991 | Olga I Lavrik | Oligonucleotides and their derivative... | |
| 1991 | E B Kopp, J J Miglietta, A G Shrutkowski, C K Shih, P M Grob, M T Skoog | Steady state kinetics and inhibition ... | KM,kcat,All properties |
| 1991 | Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Michael Kukla, Paul A J Janssen, Erik De Clercq | An antiviral target on reverse transc... | |
| 1991 | J G Baillon, N T Nashed, A Kumar, Samuel H Wilson, Donald M Jerina | A leucine zipper-like motif may media... | |
| 1991 | Robert W Sobol, R J Suhadolnik, A Kumar, B J Lee, D L Hatfield, Samuel H Wilson | Localization of a polynucleotide bind... | |
| 1991 | K B Frank, G J Noll, E V Connell, I S Sim | Kinetic interaction of human immunode... | |
| 1991 | A S De Groot, M Clerici, A Hosmalin, Stephen H Hughes, D Barnd, C W Hendrix, R Houghten, G M Shearer, J A Berzofsky | Human immunodeficiency virus reverse ... | |
| 1991 | G T Tan, A D Kinghorn, Stephen H Hughes, J M Pezzuto | Psychotrine and its O-methyl ether ar... | |
| 1991 | Brendan A Larder, K E Coates, S D Kemp | Zidovudine-resistant human immunodefi... | |
| 1991 | Stuart F J Le Grice, T Naas, B Wohlgensinger, O Schatz | Subunit-selective mutagenesis indicat... | |
| 1991 | P Hafkemeyer, K Neftel, R Hobi, A Pfaltz, H Lutz, K Lüthi, Federico Focher, Silvio Spadari, Ulrich Hübscher | HP 0.35, a cephalosporin degradation ... | RT,RNase H,All properties |
| 1991 | P R Johnson, T E Hamm, S Goldstein, S Kitov, V M Hirsch | The genetic fate of molecularly clone... | |
| 1991 | M Tisdale, T Schulze, Brendan A Larder, K Moelling | Mutations within the RNase H domain o... | |
| 1991 | E S Furfine, J E Reardon | Reverse transcriptase.RNase H from th... | RT,All properties |
| 1991 | A Jacobo-Molina, Edward Arnold | HIV reverse transcriptase structure-f... | |
| 1991 | Erik De Clercq | Chemotherapy of the acquired immune d... | |
| 1991 | Jan Balzarini, Antonin Holy, J Jindrich, H Dvorakova, Z Hao, Robert Snoeck, Piet Herdewijn, D G Johns, Erik De Clercq | 9-[(2RS)-3-fluoro-2-phosphonylmethoxy... | |
| 1991 | J H Nunberg, W A Schleif, E J Boots, J A O'Brien, J C Quintero, J M Hoffman, E A Emini, M E Goldman | Viral resistance to human immunodefic... | |
| 1991 | M H St Clair, J L Martin, G Tudor-Williams, M C Bach, C L Vavro, D M King, P Kellam, S D Kemp, Brendan A Larder | Resistance to ddI and sensitivity to ... | |
| 1991 | Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, H Nakashima, S Mori | Potent and selective inhibition of hu... | |
| 1991 | Mark A. Wainberg, R Rooke, M Tremblay, Xincang Li, Michael A. Parniak, Q Gao, X J Yao, C Tsoukas, J Montaner, M Fanning, J Ruedy | Clinical significance and characteriz... | |
| 1991 | J Abbotts, M Jaju, Samuel H Wilson | Thermodynamics of A:G mismatch poly(d... | |
| 1991 | Mark Cushman, S Kanamathareddy, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen | Synthesis and anti-HIV activities of ... | |
| 1991 | S P Becerra, A Kumar, M S Lewis, S G Widen, J Abbotts, E M Karawya, Stephen H Hughes, J Shiloach, Samuel H Wilson, M S Lewis | Protein-protein interactions of HIV-1... | |
| 1991 | Mark Cushman, P L Wang, S H Chang, C Wild, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen | Preparation and anti-HIV activities o... | |
| 1991 | A Hizi, R Tal, Stephen H Hughes | Mutational analysis of the DNA polyme... | |
| 1990 | J E Reardon, W H Miller | Human immunodeficiency virus reverse ... | KM,kcat,All properties |
| 1990 | Andrea L Ferris, A Hizi, S D Showalter, S Pichuantes, L Babe, C S Craik, Stephen H Hughes | Immunologic and proteolytic analysis ... | |
| 1990 | W E Müller, E Matthes, P Reuter, R Wenger, K Friese, Y Kuchino, H C Schröder | Effect of nonviable preparations from... | |
| 1990 | Brendan A Larder, B Chesebro, Douglas D Richman | Susceptibilities of zidovudine-suscep... | |
| 1990 | M Ricchetti, H Buc | Reverse transcriptases and genomic va... | |
| 1990 | M Tremblay, K Numazaki, H Goldman, Mark A. Wainberg | Infection of human thymic lymphocytes... | |
| 1990 | R Rooke, M Tremblay, Mark A. Wainberg | AZT (zidovudine) may act postintegrat... | |
| 1990 | F Boulerice, Mark A. Wainberg | Inhibition by AZT of HIV-1 replicatio... | |
| 1990 | Padmini S Kedar, J Abbotts, T Kovács, K Lesiak, P Torrence, Samuel H Wilson | Mechanism of HIV reverse transcriptas... | |
| 1990 | Mark A. Wainberg, Bonnie Spira, G Bleau, R Thomas | Inactivation of human immunodeficienc... | |
| 1990 | Z Hao, D A Cooney, D Farquhar, CF Perno, K Zhang, R Masood, Y Wilson, N R Hartman, Jan Balzarini, D G Johns | Potent DNA chain termination activity... | |
| 1990 | Erik De Clercq | Selective virus inhibitors. | |
| 1990 | V J Merluzzi, K D Hargrave, M Labadia, K Grozinger, M Skoog, J C Wu, C K Shih, K Eckner, S Hattox, J Adams | Inhibition of HIV-1 replication by a ... | |
| 1990 | S P Becerra, G M Clore, A M Gronenborn, A R Karlström, S J Stahl, Samuel H Wilson, P T Wingfield | Purification and characterization of ... | |
| 1990 | A M Barber, A Hizi, J V Maizel, Stephen H Hughes | HIV-1 reverse transcriptase: structur... | |
| 1990 | A I Glukhov, S A Gordeev, S V Vinogradov, V I Kiselev, V M Kramarov, O I Kiselev, E S Severin | Amplification of DNA sequences of Eps... | |
| 1990 | Stuart F J Le Grice, F Grüninger-Leitch | Rapid purification of homodimer and h... | |
| 1990 | A Hizi, Stephen H Hughes, M Shaharabany | Mutational analysis of the ribonuclea... | |
| 1990 | Erik De Clercq | Targets and strategies for the antivi... | |
| 1990 | M Tremblay, K Numazaki, X G Li, M Gornitsky, J Hiscott, Mark A. Wainberg | Resistance to infection by HIV-1 of p... | |
| 1990 | K J Williams, Lawrence A Loeb, M Fry | Synthesis of DNA by human immunodefic... | |
| 1989 | K Numazaki, X Q Bai, H Goldman, I Wong, Bonnie Spira, Mark A. Wainberg | Infection of cultured human thymic ep... | |
| 1989 | A Basu, R S Tirumalai, Mukund J Modak | Substrate binding in human immunodefi... | |
| 1989 | H E Huber, J M McCoy, J S Seehra, Charles C Richardson | Human immunodeficiency virus 1 revers... | Processivity,3-5' exo,5-3' exo,KM,Kd,RNase H,All properties |
| 1989 | Brendan A Larder, S D Kemp | Multiple mutations in HIV-1 reverse t... | |
| 1989 | Masanori Baba, Hiromichi Tanaka, Erik De Clercq, Rudi Pauwels, Jan Balzarini, Dominique Schols, H Nakashima, CF Perno, R T Walker, T Miyasaka | Highly specific inhibition of human i... | |
| 1989 | M Tremblay, M Gornitsky, Mark A. Wainberg | Active replication of human immunodef... | |
| 1989 | M Ito, Masanori Baba, A Sato, K Hirabayashi, F Tanabe, S Shigeta, Erik De Clercq | Tumor necrosis factor enhances replic... | |
| 1989 | Masanori Baba, Dominique Schols, H Nakashima, Rudi Pauwels, G Parmentier, D K Meijer, Erik De Clercq | Selective activity of several cholic ... | |
| 1989 | Dominique Schols, Masanori Baba, Rudi Pauwels, Erik De Clercq | Flow cytometric method to demonstrate... | |
| 1989 | M Tremblay, Mark A. Wainberg | Susceptibility of EBV-carrying B cell... | |
| 1989 | A Hizi, A Barber, Stephen H Hughes | Effects of small insertions on the RN... | |
| 1989 | B Müller, Tobias Restle, S Weiss, M Gautel, G Sczakiel, R S Goody | Co-expression of the subunits of the ... | |
| 1989 | C Majumdar, C A Stein, J S Cohen, S Broder, Samuel H Wilson | Stepwise mechanism of HIV reverse tra... | |
| 1989 | Fred W Perrino, Bradley D Preston, L L Sandell, Lawrence A Loeb | Extension of mismatched 3' termini of... | |
| 1989 | Erik De Clercq | Potential drugs for the treatment of ... | |
| 1988 | J D Roberts, Katarzyna Bebenek, Thomas A Kunkel | The accuracy of reverse transcriptase... | |
| 1988 | M Tremblay, L Fitz-Gibbon, Mark A. Wainberg | Heterogeneity of HIV-1 replication an... | |
| 1988 | A Hizi, C McGill, Stephen H Hughes | Expression of soluble, enzymatically ... | |
| 1988 | Erik De Clercq | Perspectives for the chemotherapy of ... | |
| 1988 | Masanori Baba, Rudi Pauwels, Jan Balzarini, J Arnout, J Desmyter, Erik De Clercq | Mechanism of inhibitory effect of dex... | |
| 1988 | E M Wondrak, J Löwer, R Kurth | Inhibition of HIV-1 RNA-dependent DNA... | |
| 1988 | Bradley D Preston, B J Poiesz, Lawrence A Loeb | Fidelity of HIV-1 reverse transcriptase. | |
| 1988 | Masanori Baba, Dominique Schols, Rudi Pauwels, Jan Balzarini, Erik De Clercq | Fuchsin acid selectively inhibits hum... | |
| 1988 | Sujit Roy, L Fitz-Gibbon, L Poulin, Mark A. Wainberg | Infection of human monocytes/macropha... | |
| 1987 | Brendan A Larder, D J Purifoy, K L Powell, G Darby | Site-specific mutagenesis of AIDS vir... | |
| 1987 | M Ito, H Nakashima, Masanori Baba, Rudi Pauwels, Erik De Clercq, S Shigeta, N Yamamoto | Inhibitory effect of glycyrrhizin on ... | |
| 1986 | H A Blough, Rudi Pauwels, Erik De Clercq, J Cogniaux, S Sprecher-Goldberger, L Thiry | Glycosylation inhibitors block the ex... | |
| 1986 | F di Marzo Veronese, T D Copeland, A L DeVico, R Rahman, S Oroszlan, R C Gallo, M G Sarngadharan | Characterization of highly immunogeni... | |
| 1986 | M M Lightfoote, J E Coligan, T M Folks, A S Fauci, M A Martin, S Venkatesan | Structural characterization of revers... | |
| 1986 | M S Johnson, M A McClure, D F Feng, J Gray, R F Doolittle | Computer analysis of retroviral pol g... | |
| 1985 | A D Hoffman, B Banapour, J A Levy | Characterization of the AIDS-associat... |
DNA sequence:
Protein information: Uniprot Q8Q292 search for HIV RT at UniProt
Sequence information: NCBI nucleotides European nucleotide archive