HIV RT
From
HIV
Welcome to the Polymerase Page
This page presents all the information in Polbase for HIV RT.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
HIV RT
is a family RT enzyme
from
HIV.
Selected Properties for HIV RT: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| No (4) | No (1) | 8.0e-06-4.7e-03 errors/bp (3) | 2.6e-05-3.2e-03 errors/bp (5) | 7.5e-05-8.0e-02 errors/bp (4) |
- References (1252)
- Structures (74)
- Sequences (0)
- Mutants (140)...
- Formulations (1)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| Mark A. Wainberg, S Bour, R Geleziunas, Z Bentwich | [Antiviral strategies in the replicat... | ||
| Erik De Clercq | Perspectives of non-nucleoside revers... | ||
| Chen Liang, Mark A. Wainberg | The role of Tat in HIV-1 replication:... | ||
| N Gashnikova, O Plyasunova, Y Kiseleva, N Fedyuk, A Pokrovsky | In vitro study of resistance-associat... | ||
| Erik De Clercq | Novel compounds in preclinical/early ... | ||
| P Hafkemeyer, K A Neftel, Ulrich HĂĽbscher | HIV-reverse transcriptase and human D... | ||
| Rudi Pauwels, M P de Bethune, Koen Andries, Paul Stoffels, P Janssen, Erik De Clercq | Discovery, development and characteri... | ||
| Erik De Clercq | New developments in anti-HIV chemothe... | ||
| Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari | Structural determinants of HIV-1 reve... | ||
| Maria Letizia Barreca, Laura De Luca, Nunzio Iraci, Angela Rao, Stefania Ferro, Giovanni Maga, Alba Chimirri | Structure-based pharmacophore identif... | ||
| Erik De Clercq | Perspectives for the chemotherapy of ... | ||
| Paul J Lewi, Marc R De Jonge, Frits F D Daeyaert, Luc Koymans, Maarten H Vinkers, Jan Heeres, Paul A J Janssen, Edward Arnold, Kalyan Das, Art D Clark, Stephen H Hughes, Paul L Boyer, Marie-Pierre P De BĂ©thune, Rudi Pauwels, Koen Andries, Michael Kukla, Donald W Ludovici, Bart De Corte, Robert W Kavash, Chih Y Ho, Paul J Lewis | On the detection of multiple-binding ... | ||
| G T Tan, J M Pezzuto, A D Kinghorn, Stephen H Hughes | Evaluation of natural products as inh... | ||
| Jorge L MartĂnez-Cajas, Nitika Pant-Pai, Marina B Klein, Mark A. Wainberg | Role of genetic diversity amongst HIV... | ||
| Erik De Clercq, Robert Snoeck | [Current acquisitions in antiviral dr... | ||
| Sherine S L Chan, Janine H Santos, Joel N Meyer, Bhaskar S Mandavilli, Dennis L Cook, Consuelo L McCash, Grace E Kissling, Abraham Nyska, Julie F Foley, Bennett Van Houten, William C Copeland, Vernon E Walker, Kristine L Witt, Jack B Bishop | Mitochondrial toxicity in hearts of C... | ||
| N Düzgünes, S Simões, V Slepushkin, E Pretzer, J J Rossi, Erik De Clercq, V P Antao, M L Collins, M C de Lima | Enhanced inhibition of HIV-1 replicat... | ||
| MarĂa-Cruz Bonache, Cristina Chamorro, Sonsoles Velázquez, Erik De Clercq, Jan Balzarini, MarĂa-JosĂ© Camarasa, Ana San-FĂ©lix | N-3 substituted TSAO derivatives as a... | ||
| 2013 | Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Xinyong Liu | Novel piperidinylamino-diarylpyrimidi... | |
| 2013 | Xuwang Chen, Yuanyuan Li, Shufang Ding, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Huiqing Liu, Xinyong Liu | Discovery of Piperidine-Linked Pyridi... | |
| 2013 | Karen A Kirby, Eleftherios Michailidis, Tracy L Fetterly, MA Steinbach, Kamalendra Singh, Bruno Marchand, Maxwell D Leslie, Ariel N Hagedorn, Eiichi N Kodama, Victor E Marquez, Stephen H Hughes, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Effects of 4' - and 2-Substitutions o... | |
| 2013 | Linda L Dunn, Paul L Boyer, Patrick K Clark, Stephen H Hughes | Mutations in HIV-1 reverse transcript... | |
| 2013 | Joseph David Bauman, Disha Patel, Chhaya Dharia, Marc Fromer, Sameer Ahmed, Yulia Volovik Frenkel, J Thomas Eck, William C Ho, Kalyan Das, Aaron J Shatkin, Edward Arnold | Detecting allosteric sites of HIV-1 r... | |
| 2013 | Ye Tian, Diwakar Rai, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Huiqing Liu, Xinyong Liu | Design, Synthesis, and Biological Eva... | |
| 2013 | A Heredia, CE Davis, MS Reitz, NM Le, MA Wainberg, JS Foulke, LX Wang, RR Redfield | Targeting of the Purine Biosynthesis ... | |
| 2013 | Matthew McCallum, Maureen Oliveira, Ruxandra-Ilinca Ibanescu, Victor G Kramer, Daniela D Moisi, Eugene L Asahchop, Bluma G Brenner, Richard Harrigan, Hongtao Xu, Mark A. Wainberg | Basis for the Early and Preferential ... | |
| 2013 | Kalyan Das, Edward Arnold | HIV-1 reverse transcriptase and antiv... | |
| 2013 | Ravindra K Gupta, DA Van de Vijver, S Manicklal, MA Wainberg | Evolving uses of oral reverse transcr... | |
| 2013 | CĂ©dric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Rita S Schildknecht, Hongtao Xu, Simani Gaseitswe, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg | The preferential selection of K65R in... | |
| 2013 | Hong-Tao Xu, Susan P Colby-Germinario, Eugene L Asahchop, Maureen Oliveira, Matthew McCallum, Susan M Schader, Yingshan Han, Yudong Quan, Stefan G Sarafianos, Mark A. Wainberg | The Effect of Mutations at Position E... | |
| 2013 | Hai-Qiu Wu, Zi-Hong Yan, Wen-Xue Chen, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Dirk Daelemans, Christophe Pannecouque | Towards new C6-rigid S-DABO HIV-1 rev... | |
| 2013 | R S K Vijayan, Edward Arnold, Kalyan Das | Molecular dynamics study of HIV-1 RT-... | |
| 2013 | Venkata Ramana Sirivolu, Sanjeev Kumar V Verneka, Tatiana Ilina, Nataliya S Myshakina, Michael A. Parniak, Zhengqiang Wang | Clicking 3'-azidothymidine into novel... | |
| 2013 | Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno Marchand, Maxwell D Leslie, Andrew D Huber, Yee Tsuey Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Hypersusceptibility mechanism of Teno... | |
| 2013 | Shiqiong Yang, Christophe Pannecouque, Dirk Daelemans, Xiao-Dong Ma, Yang Liu, Fen-Er Chen, Erik De Clercq | Molecular design, synthesis and biolo... | |
| 2013 | Jan Balzarini, Graciela Andrei, Emanuela Balestra, Dana Huskens, Christophe Vanpouille, Andrea Introini, Sonia Zicari, Sandra Liekens, Robert Snoeck, AntonĂn HolĂ˝, CF Perno, Leonid Margolis, Dominique Schols | A Multi-targeted Drug Candidate with ... | |
| 2013 | Kalyan Das, Edward Arnold | HIV-1 reverse transcriptase and antiv... | |
| 2013 | Erik De Clercq | The Nucleoside Reverse Transcriptase ... | |
| 2013 | J-H Lee, Atsuko Hachiya, S-K Shin, J Lee, Hiroyuki Gatanaga, Shinichi Oka, Karen A Kirby, Yee Tsuey Ong, Stefan G Sarafianos, William R Folk, Wangdon Yoo, Sun Pyo Hong, S-O Kim | Restriction fragment mass polymorphis... | |
| 2013 | Mariela Bollini, Kathleen M Frey, José A Cisneros, Krasimir A Spasov, Kalyan Das, Joseph David Bauman, Edward Arnold, Karen S Anderson, William L Jorgensen | Extension into the entrance channel o... | |
| 2013 | Daniel G Kuroda, Joseph David Bauman, J Reddy Challa, Disha Patel, Thomas Troxler, Kalyan Das, Edward Arnold, Robin M Hochstrasser | Snapshot of the equilibrium dynamics ... | |
| 2013 | Dongyue Li, Peng Zhan, Huiqing Liu, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2013 | Mikhail S Novikov, Vladimir T Valuev-Elliston, Denis A Babkov, Maria P Paramonova, Alexander V Ivanov, Sergey A Gavryushov, Anastasia L Khandazhinskaya, Sergey N Kochetkov, Christophe Pannecouque, Graciela Andrei, Robert Snoeck, Jan Balzarini, Katherine L Seley-Radtke | N(1),N(3)-disubstituted uracils as no... | |
| 2013 | John E Tavis, Xiaohong Cheng, Yuan Hu, Michael Totten, Feng Cao, Eleftherios Michailidis, Rajeev Aurora, Marvin J Meyers, E Jon Jacobsen, Michael A. Parniak, Stefan G Sarafianos | The hepatitis B virus ribonuclease h ... | |
| 2013 | Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd | Inhibition of HIV-1 Reverse Transcrip... | |
| 2012 | Xuwang Chen, Peng Zhan, Xin Liu, Ziheng Cheng, Caicai Meng, Siyuan Shao, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Design, synthesis, anti-HIV evaluatio... | |
| 2012 | Atsuko Hachiya, Bruno Marchand, Karen A Kirby, Eleftherios Michailidis, Xiongying Tu, Krzysztof Palczewski, Yee Tsuey Ong, Zhongjie Li, Daniel T Griffin, Matthew M Schuckmann, Junko Tanuma, Shinichi Oka, Kamalendra Singh, Eiichi N Kodama, Stefan G Sarafianos | HIV-1 reverse transcriptase (RT) poly... | |
| 2012 | Zhongjie Li, Yuan Cao, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Arylazolylthioacetanilide. Part 11: D... | |
| 2012 | Xincang Li, Peng Zhan, Erik De Clercq, Xinyong Liu | The HIV-1 Non-Nucleoside Reverse Tran... | |
| 2012 | Tatiana Ilina, Krystal Labarge, Stefan G Sarafianos, Rieko Ishima, Michael A. Parniak | Inhibitors of HIV-1 Reverse Transcrip... | |
| 2012 | Shuang-Xi Gu, Zhi-Ming Li, Xiao-Dong Ma, Shi-Qiong Yang, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Chiral resolution, absolute configura... | |
| 2012 | Christophe Vanpouille, Andrea Lisco, Andrea Introini, Jean-Charles Grivel, Arshi Munawwar, Melanie Merbah, Raymond F Schinazi, Marco Derudas, Christopher McGuigan, Jan Balzarini, Leonid Margolis | Exploiting the anti-HIV-1 activity of... | |
| 2012 | Eva-MarĂa Priego, Anna Karlsson, Federico Gago, MarĂa-JosĂ© Camarasa, Jan Balzarini, MarĂa-JesĂşs PĂ©rez-PĂ©rez | Recent advances in thymidine kinase 2... | |
| 2012 | Dante Rotili, Alberta Samuele, Domenico Tarantino, Rino Ragno, Ira Musmuca, Flavio Ballante, Giorgia Botta, Ludovica Morera, Marco Pierini, Roberto Cirilli, Maxim B Nawrozkij, Emmanuel Gonzalez, B Clotet, Marino Artico, José A Esté, Giovanni Maga, Antonello Mai | 2-(Alkyl/Aryl)Amino-6-Benzylpyrimidin... | |
| 2012 | Karen A Kirby, Bruno Marchand, Yee Tsuey Ong, Tanyaradzwa P Ndongwe, Atsuko Hachiya, Eleftherios Michailidis, Maxwell D Leslie, Daniel V Sietsema, Tracy L Fetterly, Christopher A Dorst, Kamalendra Singh, Zhengqiang Wang, Michael A. Parniak, Stefan G Sarafianos | Structural and Inhibition Studies of ... | |
| 2012 | Eleftherios Michailidis, Kamlendra Singh, Emily M Ryan, Atsuko Hachiya, Yee Tsuey Ong, Karen A Kirby, Bruno Marchand, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Effect of translocation defective rev... | |
| 2012 | Wei-Shau Hu, Stephen H Hughes | HIV-1 Reverse Transcription. | |
| 2012 | Xuwang Chen, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2012 | Martin T Christen, Lakshmi Menon, Nataliya S Myshakina, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima | Structural basis of the allosteric in... | |
| 2012 | Wenwen Chen, Peng Zhan, Erik De Clercq, Xinyong Liu | Recent progress in small molecule CCR... | |
| 2012 | Serdal Kirmizialtin, Virginia Nguyen, Kenneth A Johnson, Ron Elber | How conformational dynamics of DNA po... | |
| 2012 | Ye Tian, Peng Zhan, Diwakar Rai, Jiyan Zhang, Erik De Clercq, Xinyong Liu | Recent advances in the research of 2,... | |
| 2012 | Shiqiong Yang, Fen-Er Chen, Erik De Clercq | Dihydro-alkoxyl-benzyl-oxopyrimidine ... | |
| 2012 | Changfu Yang, Shuyuan Liu, Taisong Zhang, Yaping Hou, Xiaoli Liu, Yun Gao, Guang Yang, Zhen Wang, Huayun Chen, Ming Li, Zhenyu Zhu | Transmitted antiretroviral drug resis... | |
| 2012 | Kalyan Das, Sergio E Martinez, Joseph David Bauman, Edward Arnold | HIV-1 reverse transcriptase complex w... | |
| 2012 | Peng Zhan, Wenmin Chen, Zhongjie Li, Xincang Li, Xuwang Chen, Ye Tian, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Discovery of novel 2-(3-(2-chlorophen... | |
| 2012 | Peng Zhan, Xincang Li, Zhongjie Li, Xuwang Chen, Ye Tian, Wenmin Chen, Xinyong Liu, Christophe Pannecouque, Erik De Clercq | Structure-based bioisosterism design,... | |
| 2012 | K O François, Jan Balzarini | Potential of carbohydrate-binding age... | |
| 2012 | Marco Radi, Mafalda Pagano, Luigi Franchi, Daniele Castagnolo, Silvia Schenone, Gianni Casaluce, Claudio Zamperini, Elena Dreassi, Giovanni Maga, Alberta Samuele, Encarna Gonzalo, B Clotet, José A Esté, Maurizio Botta | Synthesis, Biological Activity, and A... | |
| 2012 | Dongyue Li, Peng Zhan, Erik De Clercq, Xinyong Liu | Strategies for the design of HIV-1 no... | |
| 2012 | Barry C Johnson, Gary T Pauly, Ganesha Rai, Disha Patel, Joseph David Bauman, Heather L Baker, Kalyan Das, Joel P Schneider, David J Maloney, Edward Arnold, Craig J Thomas, Stephen H Hughes | A comparison of the ability of rilpiv... | |
| 2012 | Paul L Boyer, Patrick K Clark, Stephen H Hughes | HIV-1 and HIV-2 Reverse Transcriptase... | |
| 2012 | Christal D Sohl, Rajesh Kasiviswanathan, Jiae Kim, Ugo Pradere, Raymond F Schinazi, William C Copeland, Hiroyuki Mitsuya, Masanori Baba, Karen S Anderson | Balancing Antiviral Potency and Host ... | |
| 2012 | Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd | DNA Polymerase β Gap-filling Transles... | |
| 2012 | Kamalendra Singh, Bruno Marchand, Devendra K Rai, Bechan Sharma, Eleftherios Michailidis, Emily M Ryan, Kayla B Matzek, Maxwell D Leslie, Ariel N Hagedorn, Zhongjie Li, Pieter R Norden, Atsuko Hachiya, Michael A. Parniak, Hong-Tao Xu, Mark A. Wainberg, Stefan G Sarafianos | Biochemical Mechanism of HIV-1 Resist... | |
| 2012 | Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valeria Famiglini, Sandro Cosconati, Giovanni Maga, Alberta Samuele, Emmanuel Gonzales, B Clotet, Dominique Schols, Jose Este, Ettore Novellino, Romano Silvestri | New Nitrogen Containing Substituents ... | |
| 2012 | Victor G Kramer, Susan M Schader, Maureen Oliveira, Susan P Colby-Germinario, Daniel A Donahue, Diane N Singhroy, Randy Tressler, Richard D Sloan, Mark A. Wainberg | Maraviroc and other HIV-1 entry inhib... | |
| 2012 | Sergio R Ribone, Volker Leen, Marcela Madrid, Wim Dehaen, Dirk Daelemans, Christophe Pannecouque, Margarita C Briñón | Synthesis, biological evaluation and ... | |
| 2011 | Zhinan Jin, Jerome Deval, Kenneth A Johnson, David C Swinney | Characterization of the elongation co... | |
| 2011 | Karen A Kirby, Kamalendra Singh, Eleftherios Michailidis, Bruno Marchand, Eiichi N Kodama, Noriyuki Ashida, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | The sugar ring conformation of 4'-eth... | |
| 2011 | Suhman Chung, Jennifer T Miller, Barry C Johnson, Stephen H Hughes, Stuart F J Le Grice | Mutagenesis of the human immunodefici... | |
| 2011 | Graciela Andrei, Andrea Lisco, Christophe Vanpouille, Andrea Introini, Emanuela Balestra, Joost van den Oord, Tomas Cihlar, CF Perno, Robert Snoeck, Leonid Margolis, Jan Balzarini | Topical tenofovir, a microbicide effe... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | 6-Benzoyl-3-hydroxypyrimidine-2,4-dio... | |
| 2011 | Suhman Chung, Daniel M Himmel, Jian-Kang Jiang, Krzysztof Wojtak, Joseph David Bauman, Jason W Rausch, Jennifer A Wilson, John A Beutler, Craig J Thomas, Edward Arnold, Stuart F J Le Grice | Synthesis, activity, and structural a... | |
| 2011 | Peibin Zeng, Jingxing Wang, Yi Huang, Xiaoming Guo, Jinming Li, Guoxin Wen, Tonghan Yang, Zhongqiao Yun, Miao He, Yu Liu, Yuzhe Yuan, Jane Schulmann, Simone Glynn, Paul Ness, J Brooks Jackson, Hua Shan | The human immunodeficiency virus-1 ge... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | N-3 Hydroxylation of Pyrimidine-2,4-d... | |
| 2011 | Yuan Yuan, Hui Xing, Xiao-Yu Wang, Chun-hua Liu, Li-Ting Yang, Ben-Feng Zheng, Xia Wang, Yu-Hua Ruan, Zhe Wang, Hong-wei Liu, Yi-ming Shao | [The prevalence of HIV-1 drug resista... | |
| 2011 | Brian J Scarth, Suzanne McCormick, Matthias Götte | Effects of mutations F61A and A62V in... | |
| 2011 | Chandravanu Dash, Yousef Ahmadibeni, Michael J Hanley, Jui Pandhare, Mathias Gotte, Stuart F J Le Grice, Keykavous Parang | Inhibition of multi-drug resistant HI... | |
| 2011 | Peng Zhan, Xuwang Chen, Dongyue Li, Zengjun Fang, Erik De Clercq, Xinyong Liu | HIV-1 NNRTIs: Structural diversity, p... | |
| 2011 | Jing Zhang, Peng Zhan, Jingde Wu, Zhongjie Li, Yan Jiang, Weiying Ge, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2011 | Anick Auger, Greg L Beilhartz, Siqi Zhu, Elizabeth Cauchon, Jean-Pierre Falgueyret, Jay A Grobler, Maryam Ehteshami, Matthias Götte, Roman A Melnyk | Impact of primer-induced conformation... | |
| 2011 | O Jegede, A Khodyakova, M Chernov, J Weber, L Menéndez-Arias, A Gudkov, ME Quiñones-Mateu | Identification of low-molecular weigh... | |
| 2011 | Joseph David Bauman, Disha Patel, Edward Arnold | Fragment Screening and HIV Therapeutics. | |
| 2011 | Alberta Samuele, Sara Bisi, Alexandra Kataropoulou, Giuseppe La Regina, Francesco Piscitelli, Valerio Gatti, Romano Silvestri, Giovanni Maga | Mechanism of interaction of novel ind... | |
| 2011 | Mikhail S Novikov, Olga N Ivanova, Alexander V Ivanov, Alexander A Ozerov, Vladimir T Valuev-Elliston, Kartik Temburnikar, Galina V Gurskaya, Sergey N Kochetkov, Christophe Pannecouque, Jan Balzarini, Katherine L Seley-Radtke | 1-[2-(2-Benzoyl- and 2-benzylphenoxy)... | |
| 2011 | Mingyan Yu, Zhongjie Li, Shuai Liu, Erkang Fan, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2011 | Erik De Clercq | A 40-year journey in search of select... | |
| 2011 | Matthew W Kellinger, Kenneth A Johnson | Role of induced fit in limiting discr... | |
| 2011 | Mark A Ditzler, Debojit Bose, Nikolozi Shkriabai, Bruno Marchand, Stefan G Sarafianos, Mamuka Kvaratskhelia, Donald H Burke | Broad-spectrum aptamer inhibitors of ... | |
| 2011 | Tanyaradzwa P Ndongwe, Adeyemi O Adedeji, Eleftherios Michailidis, Yee Tsuey Ong, Atsuko Hachiya, Bruno Marchand, Emily M Ryan, Devendra K Rai, Karen A Kirby, Angela S Whatley, Donald H Burke, Marc Johnson, Shilei Ding, Yi-Min Zheng, Shan-Lu Liu, Ei-Ichi Kodama, Krista A Delviks-Frankenberry, Vinay K Pathak, Hiroyuki Mitsuya, Michael A. Parniak, Kamalendra Singh, Stefan G Sarafianos | Biochemical, inhibition and inhibitor... | |
| 2011 | Atsuko Hachiya, Eiichi N Kodama, Matthew M Schuckmann, Karen A Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G Sarafianos | K70Q adds high-level tenofovir resist... | |
| 2011 | Brian D Herman, Raymond F Schinazi, Hong-Wang Zhang, James H Nettles, Richard Stanton, Mervi Detorio, Aleksandr Obikhod, Ugo Pradère, Steven J Coats, John W Mellors, Nicolas Sluis-Cremer | Substrate mimicry: HIV-1 reverse tran... | |
| 2011 | Allison K Delong, Mingham Wu, Diane Bennett, Neil Parkin, Zhijin Wu, Joseph W Hogan, Rami Kantor | Sequence Quality Analysis Tool (SQUAT... | |
| 2011 | Stefania Butini, Sandra Gemma, Margherita Brindisi, Giuseppe Borrelli, Isabella Fiorini, Alberta Samuele, Aristotele Karytinos, Marcella Facchini, Andrea Lossani, Samantha Zanoli, Giuseppe Campiani, Ettore Novellino, Federico Focher, Giovanni Maga | Enantioselective binding of second ge... | |
| 2011 | Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valerio Gatti, Giovanni Maga, Alberta Samuele, Christophe Pannecouque, Dominique Schols, Jan Balzarini, Ettore Novellino, Romano Silvestri | Indolylarylsulfones as HIV-1 non-nucl... | |
| 2011 | Han-Ping Li, Wei Guo, Yong-Jian Liu, Zuo-Yi Bao, Lin Li, Dao-Min Zhuang, Si-Yang Liu, Zhengqiang Wang, Xiao-Lin Wang, Jing-Yun Li | [Screening program on novel drug resi... | |
| 2011 | Claudette S Satchell, Jane A O'Halloran, Aoife G Cotter, Aaron J Peace, Eileen F O'Connor, Anthony F Tedesco, Eoin R Feeney, John S Lambert, Gerard J Sheehan, Dermot Kenny, Patrick W G Mallon | Increased Platelet Reactivity in HIV-... | |
| 2011 | Xuwang Chen, Peng Zhan, Dongyue Li, Erik De Clercq, Xinyong Liu | Recent advances in DAPYs and related ... | |
| 2011 | Matthias Götte | Initiation of HIV reverse transcripti... | |
| 2011 | Brian J Scarth, Kirsten L White, James M Chen, Eric B Lansdon, S Swaminathan, Michael D Miller, Matthias Götte | Mechanism of resistance to GS-9148 co... | |
| 2011 | Dante Rotili, Domenico Tarantino, Marino Artico, Maxim B Nawrozkij, Emmanuel Gonzalez-Ortega, B Clotet, Alberta Samuele, José A Esté, Giovanni Maga, Antonello Mai | Diarylpyrimidine-dihydrobenzyloxopyri... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Mathieu Metifiot, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | 3-Hydroxypyrimidine-2,4-diones as an ... | |
| 2011 | Anthony K Felts, Krystal Labarge, Joseph David Bauman, Dishaben V Patel, Daniel M Himmel, Edward Arnold, Michael A. Parniak, Ronald M Levy | Identification of alternative binding... | |
| 2011 | Dimitrios Coutsinos, CĂ©dric F Invernizzi, Daniela D Moisi, Maureen Oliveira, Jorge L Martinez-Cajas, Bluma G Brenner, Mark A. Wainberg | A template-dependent dislocation mech... | |
| 2011 | MarĂa-Cruz Bonache, Alessandra Cordeiro, Ernesto Quesada, Els Vanstreels, Dirk Daelemans, MarĂa-JosĂ© Camarasa, Jan Balzarini, Ana San-FĂ©lix | Selective inhibition of Human Immunod... | |
| 2011 | Tao Dong, Yongqing Zhang, Ke Yi Xu, Huiping Yan, Ian James, Yanchun Peng, Marie-Eve Blais, Silvana Gaudieri, Xinyue Chen, Wenhui Lun, Hao Wu, Wen Yan Qu, Tim Rostron, Ning Li, Yu Mao, Simon Mallal, Xiaoning Xu, Andrew McMichael, Mina John, Sarah L Rowland-Jones | Extensive HLA-driven viral diversity ... | |
| 2011 | Qingguo Gong, Lakshmi Menon, Tatiana Ilina, Lena G Miller, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima | Interaction of HIV-1 reverse transcri... | |
| 2011 | Kalyan Das, Joseph David Bauman, Angela S Rim, Chhaya Dharia, Arthur D Clark, MarĂa-JosĂ© Camarasa, Jan Balzarini, Edward Arnold | Crystal structure of tert-butyldimeth... | |
| 2011 | Xiao-Dong Ma, Shi-Qiong Yang, Shuang-Xi Gu, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV activity of ar... | |
| 2011 | Eugene L Asahchop, Maureen Oliveira, Mark A. Wainberg, Bluma G Brenner, Daniela D Moisi, Thomas D'Aquin Toni, Cecile L Tremblay | Characterization of the E138K resista... | |
| 2011 | Hong-Tao Xu, Eugene L Asahchop, Maureen Oliveira, Peter K Quashie, Yudong Quan, Bluma G Brenner, Mark A. Wainberg | Compensation by the E138K mutation in... | |
| 2011 | Bluma G Brenner, Matthew Lowe, Daniela D Moisi, Isabelle Hardy, Simon Gagnon, Hugues Charest, Jean Guy Baril, Mark A. Wainberg, Michel Roger | Subtype diversity associated with the... | |
| 2011 | Jing-Rong Ye, Lei Guo, Hong-Yan Lu, Ruo-Lei Xin, Yi Zeng | [Genotypic resistance mutations to an... | |
| 2011 | Mark A. Wainberg, Daniela D Moisi, Maureen Oliveira, Thomas D'Aquin Toni, Bluma G Brenner | Transmission dynamics of the M184V dr... | |
| 2010 | Martin Di Grandi, Matthew Olson, Amar S Prashad, Geraldine Bebernitz, Amara Luckay, Stanley Mullen, Yongbo Hu, Girija Krishnamurthy, Keith Pitts, John O'Connell | Small molecule inhibitors of HIV RT R... | |
| 2010 | Guozhi Tang, Denis J Kertesz, Minmin Yang, Xianfeng Lin, Zhengqiang Wang, Wentao Li, Zongxing Qiu, Junli Chen, Jianghua Mei, Li Chen, Taraneh Mirzadegan, Seth F Harris, Armando G Villaseñor, Jennifer Fretland, William L Fitch, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp | Exploration of piperidine-4-yl-aminop... | |
| 2010 | Matthias Götte, Jason W Rausch, Bruno Marchand, Stefan G Sarafianos, Stuart F J Le Grice | Reverse transcriptase in motion: conf... | |
| 2010 | Daniel A Donahue, Richard D Sloan, Björn D Kuhl, Tamara Bar-Magen, Susan M Schader, Mark A. Wainberg | Stage-dependent inhibition of HIV-1 r... | |
| 2010 | Eric B Lansdon, Dharmaraj Samuel, Leanna Lagpacan, Katherine M Brendza, Kirsten L White, Magdeleine Hung, Xiaohong Liu, Constantine G Boojamra, Richard L Mackman, Tomas Cihlar, Adrian S Ray, Mary E McGrath, S Swaminathan | Visualizing the molecular interaction... | RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Polymerase Catalytic Residue Amino Acids,Residues Involved in Catalysis of RNase H,Incorporation of non-standard nucleotides,All properties |
| 2010 | Romuald Corbau, Julie Mori, Chris Phillips, Lesley Fishburn, Alex Martin, Charles Mowbray, Wendy Panton, Caroline Smith-Burchnell, Adele Thornberry, Heather Ringrose, Thorsten Knöchel, Steve Irving, Mike Westby, Anthony Wood, Manos Perros | Lersivirine: a Non-Nucleoside Reverse... | RT,All properties |
| 2010 | Michael E Abram, Andrea L Ferris, Wei Shao, W Gregory Alvord, Stephen H Hughes | Nature, position, and frequency of mu... | |
| 2010 | Alberta Samuele, Emmanuele Crespan, Samanta Vitellaro, Anna-Maria Monforte, Patrizia Logoteta, Alba Chimirri, Giovanni Maga | Slow binding-tight binding interactio... | |
| 2010 | Denis J Kertesz, Christine Brotherton-Pleiss, Minmin Yang, Zhengqiang Wang, Xianfeng Lin, Zongxing Qiu, Donald R Hirschfeld, Shelley K Gleason, Taraneh Mirzadegan, Pete W Dunten, Seth F Harris, Armando G Villaseñor, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp | Discovery of piperidin-4-yl-aminopyri... | RT,All properties |
| 2010 | Xiongying Tu, Kalyan Das, Qianwei Han, Joseph David Bauman, Arthur D Clark, Xiaorong Hou, Yulia Volovik Frenkel, Barbara L Gaffney, Roger A Jones, Paul L Boyer, Stephen H Hughes, Stefan G Sarafianos, Edward Arnold | Structural basis of HIV-1 resistance ... | |
| 2010 | Zhengqiang Wang, Jing Tang, Christine E Salomon, Christine D Dreis, Robert Vince | Pharmacophore and structure-activity ... | |
| 2010 | Yuhua Ruan, Hui Xing, Xia Wang, Heng Tang, Zhengqiang Wang, Hongwei Liu, Bin Su, Jianjun Wu, Hanping Li, Lingjie Liao, Jinming Li, Julia Wei Wu, Yiming Shao | Virologic outcomes of first-line HAAR... | |
| 2010 | Guido van Marle, Deirdre L Church, Kali D Nunweiler, Kris Cannon, Mark A. Wainberg, M John Gill | Higher levels of Zidovudine resistant... | |
| 2010 | Hong-Tao Xu, Yudong Quan, Eugene L Asahchop, Maureen Oliveira, Daniella Moisi, Mark A. Wainberg | Comparative biochemical analysis of r... | |
| 2010 | Li-Jia Xu, Zong-Gen Peng, Hong-Shan Chen, Jie Wang, Pei-Gen Xiao | Bioactive triterpenoids from Kadsura ... | |
| 2010 | Anna-Maria Monforte, Patrizia Logoteta, Laura De Luca, Nunzio Iraci, Stefania Ferro, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Novel 1,3-dihydro-benzimidazol-2-ones... | |
| 2010 | Michael L Mitchell, Jong Chan Son, Ill Young Lee, Chong-Kyo Lee, Hae Soo Kim, Hongyan Guo, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Gene Eisenberg, Romas Geleziunas, Lianhong Xu, Choung U Kim | N1-Heterocyclic pyrimidinediones as n... | RT,All properties |
| 2010 | Viktor von Wyl, Maryam Ehteshami, Jori Symons, Philippe Bürgisser, Monique Nijhuis, Lisa M Demeter, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard | Epidemiological and biological eviden... | |
| 2010 | Mia J Biondi, Greg L Beilhartz, Suzanne McCormick, Matthias Götte | N348I in HIV-1 reverse transcriptase ... | |
| 2010 | Dimitrios Coutsinos, CĂ©dric F Invernizzi, Hongtao Xu, Bluma G Brenner, Mark A. Wainberg | Factors affecting template usage in t... | |
| 2010 | Suhman Chung, Michaela Wendeler, Jason W Rausch, Greg L Beilhartz, Matthias Gotte, Barry R O'Keefe, Alun Bermingham, John A Beutler, Shixin Liu, Xiaowei Zhuang, Stuart F J Le Grice | Structure-activity analysis of vinylo... | |
| 2010 | Matthew W Kellinger, Kenneth A Johnson | Nucleotide-dependent conformational c... | RT,All properties |
| 2010 | Hong-Tao Xu, Maureen Oliveira, Yudong Quan, Tamara Bar-Magen, Mark A. Wainberg | Differential impact of the HIV-1 non-... | |
| 2010 | Hua-Poo Su, Youwei Yan, G Sridhar Prasad, Robert F Smith, Christopher L Daniels, Pravien D Abeywickrema, John C Reid, H Marie Loughran, Maria Kornienko, Sujata Sharma, Jay A Grobler, Bei Xu, Vinod Sardana, Timothy J Allison, Peter D Williams, Paul L Darke, Daria J Hazuda, Sanjeev Munshi | Structural basis for the inhibition o... | RT,RNase H,All properties |
| 2010 | Michael L Mitchell, Jong Chan Son, Hongyan Guo, Yun-A Im, Eun Jung Cho, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Doris Graupe, Gerry Rhodes, Gong-Xin He, Romas Geleziunas, Lianhong Xu, Choung U Kim | N1-Alkyl pyrimidinediones as non-nucl... | RT,All properties |
| 2010 | Viktor von Wyl, Maryam Ehteshami, Lisa M Demeter, Philippe Bürgisser, Monique Nijhuis, Jori Symons, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard | HIV-1 reverse transcriptase connectio... | |
| 2010 | Greg L Beilhartz, Matthias Götte | HIV-1 Ribonuclease H: Structure, Cata... | |
| 2010 | Erik De Clercq | In search of a selective therapy of v... | |
| 2010 | Brian D Herman, Ivan Votruba, Antonin Holy, Nicolas Sluis-Cremer, Jan Balzarini | The acyclic 2,4-diaminopyrimidine nuc... | |
| 2010 | Matthew M Schuckmann, Bruno Marchand, Atsuko Hachiya, Eiichi N Kodama, Karen A Kirby, Kamalendra Singh, Stefan G Sarafianos | The N348I mutation at the connection ... | |
| 2010 | SĂ©verine Freisz, Guillaume Bec, Marco Radi, Philippe Wolff, Emmanuele Crespan, Lucilla Angeli, Philippe Dumas, Giovanni Maga, Maurizio Botta, Eric Ennifar | Crystal Structure of HIV-1 Reverse Tr... | RT,All properties |
| 2010 | Zhao-Sen Zeng, Qiu-Qin He, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Hybrid diarylbenzopyrimidine non-nucl... | |
| 2010 | Zhao-Sen Zeng, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq | Lead optimization of diarylpyrimidine... | |
| 2010 | Yong-Hong Liang, Qiu-Qin He, Zhao-Sen Zeng, Zhi-Qian Liu, Xiao-Qing Feng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq | Synthesis and anti-HIV activity of 2-... | |
| 2010 | Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq | 1,2,3-thiadiazole thioacetanilides. P... | |
| 2010 | Wujie Li, Mou Cao, Lu Pei, Xiaomei Ling, Bingchao Li, Zhenjun Yang | Study on steady-state kinetics of nuc... | RT,All properties |
| 2010 | Michael E Abram, Stefan G Sarafianos, Michael A. Parniak | The mutation T477A in HIV-1 reverse t... | |
| 2010 | H Nina Kim, Jing Wang, James Hughes, Robert Coombs, Jorge Sanchez, Stewart Reid, Sinead Delany-Moretlwe, Frances Cowan, Jonathan Fuchs, Susan H Eshleman, Leila Khaki, Moira A McMahon, Robert F Siliciano, Anna Wald, Connie Celum | Effect of acyclovir on HIV-1 set poin... | |
| 2010 | Erik De Clercq | Antiretroviral drugs. | |
| 2010 | John C Martin, Michael J M Hitchcock, Erik De Clercq, William H Prusoff | Early nucleoside reverse transcriptas... | |
| 2010 | Pankaj R Daga, Jinsong Duan, Robert J Doerksen | Computational model of hepatitis B vi... | |
| 2010 | Eric B Lansdon, Katherine M Brendza, Magdeleine Hung, Ruth Wang, Susmith Mukund, Debi Jin, Gabriel Birkus, Nilima Kutty, Xiaohong Liu | Crystal structures of HIV-1 reverse t... | RT,Associated condition,All properties |
| 2010 | Giovanni Maga, Marco Radi, Marie-Aline Gerard, Maurizio Botta, Eric Ennifar | HIV-1 RT Inhibitors with a Novel Mech... | |
| 2009 | Hongtao Xu, Yudong Quan, Bluma G Brenner, Tamara Bar-Magen, Maureen Oliveira, Susan M Schader, Mark A. Wainberg | Human immunodeficiency virus type 1 r... | |
| 2009 | Anders Vahlne | A historical reflection on the discov... | |
| 2009 | Kristina A Paris, Omar Haq, Anthony K Felts, Kalyan Das, Edward Arnold, Ronald M Levy | Conformational landscape of the human... | |
| 2009 | MC Puertas, MJ Buzón, A Artese, S Alcaro, L Menéndez-Arias, CF Perno, B Clotet, F Ceccherini-Silberstein, J Martinez-Picado | Effect of the human immunodeficiency ... | |
| 2009 | Stefan G Sarafianos, Bruno Marchand, Kalyan Das, Daniel M Himmel, Michael A. Parniak, Stephen H Hughes, Edward Arnold | Structure and function of HIV-1 rever... | |
| 2009 | Peng Zhan, Xinyong Liu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Synthesis and anti-HIV activity evalu... | |
| 2009 | Peng Zhan, Xinyong Liu, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Design strategies of novel NNRTIs to ... | |
| 2009 | Peng Zhan, Xinyong Liu, Zengjun Fang, Christophe Pannecouque, Erik De Clercq | 1,2,3-Selenadiazole thioacetanilides:... | |
| 2009 | Atsuko Hachiya, Kazuki Shimane, Stefan G Sarafianos, Eiichi N Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi, Shinichi Oka | Clinical relevance of substitutions i... | |
| 2009 | Erik De Clercq | A new drug combination therapy for tr... | |
| 2009 | Takeshi Naito, Kazuki Izumi, Eiichi N Kodama, Yasuko Sakagami, Keiko Kajiwara, Hiroki Nishikawa, Kentaro Watanabe, Stefan G Sarafianos, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka | SC29EK, a peptide fusion inhibitor wi... | |
| 2009 | Kazuki Izumi, Eiichi N Kodama, Kazuya Shimura, Yasuko Sakagami, Kentaro Watanabe, Saori Ito, Tsuyoshi Watabe, Yukihiro Terakawa, Hiroki Nishikawa, Stefan G Sarafianos, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka | Design of peptide-based inhibitors fo... | |
| 2009 | Peng Zhan, Xinyong Liu, Junjie Zhu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Synthesis and biological evaluation o... | |
| 2009 | Dimitrios Coutsinos, CĂ©dric F Invernizzi, Hongtao Xu, Daniela D Moisi, Maureen Oliveira, Bluma G Brenner, Mark A. Wainberg | Template usage is responsible for the... | |
| 2009 | Bo-Liang Deng, Yaofeng Zhao, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis of alkenyldiarylmethanes (A... | |
| 2009 | Peng Zhan, Zhongjie Li, Xinyong Liu, Erik De Clercq | Sulfanyltriazole/tetrazoles: a promis... | |
| 2009 | Yoshiyuki Mizushina, Hirohisa Motoshima, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Ken Hirano, Fumio Sugawara, Hiromi Yoshida | 3-O-methylfunicone, a selective inhib... | |
| 2009 | Daniel M Himmel, Karen A Maegley, Tom A Pauly, Joseph David Bauman, Kalyan Das, Chhaya Dharia, Arthur D Clark, Kevin Ryan, Michael J Hickey, Robert A Love, Stephen H Hughes, Simon Bergqvist, Edward Arnold | Structure of HIV-1 reverse transcript... | RT,RNase H,All properties |
| 2009 | Hironori Nishitsuji, Takaya Hayashi, Tomosaburo Takahashi, Masashi Miyano, Mari Kannagi, Takao Masuda | Augmentation of reverse transcription... | |
| 2009 | Xuexiang Zhang, Xueyan Jiang, Hongzhou Lu, Fang Shen, Jiangrong Wang | Dyslipidaemia and Intima-Media Thickn... | |
| 2009 | Alberta Samuele, Alexandra Kataropoulou, Marco Viola, Samantha Zanoli, Giuseppe La Regina, Francesco Piscitelli, Romano Silvestri, Giovanni Maga | Non-nucleoside HIV-1 reverse transcri... | |
| 2009 | Stefania Butini, Margherita Brindisi, Sandro Cosconati, Luciana Marinelli, Giuseppe Borrelli, Salvatore Sanna Coccone, Anna Ramunno, Giuseppe Campiani, Ettore Novellino, Samantha Zanoli, Alberta Samuele, Gianluca Giorgi, Alberto Bergamini, Michela Di Mattia, Silvana Lalli, Bruno Galletti, Sandra Gemma, Giovanni Maga | Specific targeting of highly conserve... | |
| 2009 | Kalyan Das, Rajiv P Bandwar, Kirsten L White, Joy Y Feng, Stefan G Sarafianos, Steven Tuske, Xiongying Tu, Arthur D Clark, Paul L Boyer, Xiaorong Hou, Barbara L Gaffney, Roger A Jones, Michael D Miller, Stephen H Hughes, Edward Arnold | Structural basis for the role of the ... | RT,All properties |
| 2009 | Susan P Colby-Germinario, Adan Rios, Jorge Quesada, Dallas Anderson, Allan L Goldstein, Theresa Fossum, Mark A. Wainberg | HIV inactivation by cross-linking of ... | |
| 2009 | Egor P Tchesnokov, Aleksandr Obikhod, Ivana Massud, Andrea Lisco, Christophe Vanpouille, Beda Brichacek, Jan Balzarini, Christopher McGuigan, Marco Derudas, Leonid Margolis, Raymond F Schinazi, Matthias Götte | Mechanisms associated with HIV-1 resi... | |
| 2009 | Thorsten A Kirschberg, Mini Balakrishnan, Neil H Squires, Tiffany Barnes, Katherine M Brendza, Xiaowu Chen, Eugene J Eisenberg, Weili Jin, Nilima Kutty, Stephanie Leavitt, Albert C Liclican, Qi Liu, Xiaohong Liu, John Mak, Jason K Perry, Michael Wang, William J Watkins, Eric B Lansdon | RNase H active site inhibitors of hum... | |
| 2009 | Franck Chiappini, Elina Teicher, Raphaël Saffroy, Brigitte Debuire, Daniel Vittecoq, Antoinette Lemoine | Relationship between polymerase gamma... | |
| 2009 | Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2009 | Yong-Hong Liang, Xiao-Qing Feng, Zhao-Sen Zeng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq | Design, synthesis, and SAR of naphthy... | |
| 2009 | Marco Derudas, Davide Carta, Andrea Brancale, Christophe Vanpouille, Andrea Lisco, Leonid Margolis, Jan Balzarini, Christopher McGuigan | The application of phosphoramidate pr... | |
| 2009 | Erik De Clercq | Anti-HIV drugs: 25 compounds approved... | |
| 2009 | Dharmesh H Mahajan, Christophe Pannecouque, Erik De Clercq, Kishor H Chikhalia | Synthesis and studies of new 2-(couma... | |
| 2009 | Marco Radi, Giovanni Maga, Maddalena Alongi, Lucilla Angeli, Alberta Samuele, Samantha Zanoli, Luca Bellucci, Andrea Tafi, Gianni Casaluce, Gianluca Giorgi, Mercedes Armand-Ugon, Emmanuel Gonzalez, José A Esté, Mireille Baltzinger, Guillaume Bec, Philippe Dumas, Eric Ennifar, Maurizio Botta | Discovery of chiral cyclopropyl dihyd... | |
| 2009 | Paul L Boyer, B Christie Vu, Zandrea Ambrose, John G Julias, Svenja Warnecke, Chenzhong Liao, Chris Meier, Victor E Marquez, Stephen H Hughes | The nucleoside analogue D-carba T blo... | |
| 2009 | CĂ©dric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg | Signature nucleotide polymorphisms at... | |
| 2009 | Alexandra Kataropoulou, Chiara Bovolenta, Amalia Belfiore, Sonia Trabatti, Anna Garbelli, Simona Porcellini, Rossella Lupo, Giovanni Maga | Mutational analysis of the HIV-1 auxi... | |
| 2009 | Young-Sam Lee, W Dexter Kennedy, Y Whitney Yin | Structural insight into processive hu... | |
| 2009 | Greg L Beilhartz, Michaela Wendeler, Noel S Baichoo, Jason W Rausch, Stuart F J Le Grice, Matthias Götte | HIV-1 reverse transcriptase can simul... | |
| 2009 | Dan Turner, Eduardo Shahar, Eugene Katchman, Eynat Kedem, Natasha Matus, Michal Katzir, Gamal Hassoun, Shimon Pollack, Rivka Kessner, Mark A. Wainberg, Boaz Avidor | Prevalence of the K65R resistance rev... | |
| 2009 | Anna-Maria Monforte, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Design, synthesis, and structure-acti... | |
| 2009 | Francesco Piscitelli, Antonio Coluccia, Andrea Brancale, Giuseppe La Regina, Anna Sansone, Cesare Giordano, Jan Balzarini, Giovanni Maga, Samantha Zanoli, Alberta Samuele, Roberto Cirilli, Francesco La Torre, Antonio Lavecchia, Ettore Novellino, Romano Silvestri | Indolylarylsulfones bearing natural a... | |
| 2009 | Yudong Quan, Chen Liang, Bluma G Brenner, Mark A. Wainberg | Multidrug-resistant variants of HIV t... | |
| 2009 | Matthew D Cullen, William C Ho, Joseph David Bauman, Kalyan Das, Edward Arnold, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Crystallographic study of a novel sub... | RT,All properties |
| 2009 | Dai-Shi Su, John J Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J Felock, Meiqing Lu, Ming-Tain Lai, Sinoeun Touch, Gregory Moyer, Daniel J Distefano, Jessica A Flynn, Yuexia Liang, Rosa Sanchez, Sridhar Prasad, Youwei Yan, Rebecca A Perlow-Poehnelt, Maricel Torrent, Michael D Miller, Joe P Vacca, Theresa M Williams, Neville J Anthony | Substituted tetrahydroquinolines as p... | RT,All properties |
| 2009 | L Menéndez-Arias | Mutation Rates and Intrinsic Fidelity... | Frameshift Error Rate,All properties |
| 2009 | Takuma Kimura, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Eiji Ohashi, Haruo Ohmori, Chikahide Masutani, Fumio Hanaoka, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Penicilliols A and B, novel inhibitor... | |
| 2009 | Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and in vitro anti-HIV evalu... | |
| 2009 | Linda L Dunn, Mary Jane McWilliams, Kalyan Das, Edward Arnold, Stephen H Hughes | Mutations in the thumb allow human im... | |
| 2008 | Fang Yu, Xinyong Liu, Peng Zhan, Erik De Clercq | Recent advances in the research of HI... | |
| 2008 | Zhijian Zhao, Scott E Wolkenberg, Philip E J Sanderson, Meiqing Lu, Vandna Munshi, Gregory Moyer, Meizhen Feng, Anthony V Carella, Linda T Ecto, Lori J Gabryelski, Ming-Tain Lai, Sridar G Prasad, Youwei Yan, Georgia B McGaughey, Michael D Miller, Craig W Lindsley, George D Hartman, Joseph P Vacca, Theresa M Williams | Novel indole-3-sulfonamides as potent... | RT,All properties |
| 2008 | Zachary K Sweeney, Seth F Harris, Seth F Arora, Hassan Javanbakht, Yingqian Li, Jennifer Fretland, James P Davidson, J Roland Billedeau, Shelley K Gleason, Donald R Hirschfeld, Joshua J Kennedy-Smith, Taraneh Mirzadegan, Ralf Roetz, Mark Smith, Sarah Sperry, Judy M Suh, Jeffrey Wu, Stan Tsing, Armando G Villaseñor, Amber Paul, Guoping Su, Gabrielle M Heilek, Julie Qi Hang, Amy S Zhou, Jesper A Jernelius, Fang-Jie Zhang, Klaus Klumpp | Design of annulated pyrazoles as inhi... | RT,All properties |
| 2008 | Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Marco Ponassi, Torsten Unge, Martino Bolognesi | Crystal structures of HIV-1 reverse t... | RT,All properties |
| 2008 | Andrea Lisco, Christophe Vanpouille, Egor P Tchesnokov, Jean-Charles Grivel, Angélique Biancotto, Beda Brichacek, Julie Elliott, Emilie Fromentin, Robin Shattock, Peter Anton, Robert Gorelick, Jan Balzarini, Christopher McGuigan, Marco Derudas, Matthias Götte, Raymond F Schinazi, Leonid Margolis | Acyclovir is activated into a HIV-1 r... | RT,All properties |
| 2008 | Matthew D Cullen, York-Fong Cheung, Miles D Houslay, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Investigation of the alkenyldiarylmet... | |
| 2008 | Maryam Ehteshami, Matthias Götte | Effects of mutations in the connectio... | |
| 2008 | Samir Abdurahman, Akos Végvári, Masoud Youssefi, Michael Levi, Stefan Höglund, Elin Andersson, Peter Horal, Bo Svennerholm, Jan Balzarini, Anders Vahlne | Activity of the small modified amino ... | |
| 2008 | Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte | Delayed chain termination protects th... | |
| 2008 | Michel L Ntemgwa, Thomas D'Aquin Toni, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Maureen Oliveira, Mark A. Wainberg | Near full-length genomic analysis of ... | |
| 2008 | Erik De Clercq | Emerging antiviral drugs. | |
| 2008 | Yueping Wang, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse-transcri... | |
| 2008 | Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and biological evaluation o... | |
| 2008 | Bluma G Brenner, Michel Roger, Daniela D Moisi, Maureen Oliveira, Isabelle Hardy, Reuven Turgel, Hugues Charest, Jean-Pierre Routy, Mark A. Wainberg | Transmission networks of drug resista... | |
| 2008 | Chandravanu Dash, Brian J Scarth, Christopher Badorrek, Matthias Götte, Stuart F J Le Grice | Examining the ribonuclease H primer g... | |
| 2008 | Zhengqiang Wang, Robert Vince | Synthesis of pyrimidine and quinolone... | |
| 2008 | Bechan Sharma, Emmanuele Crespan, Giuseppe Villani, Giovanni Maga | The balance between the rates of inco... | |
| 2008 | Takuma Kimura, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Novel azaphilones, kasanosins A and B... | |
| 2008 | Samantha Zanoli, Sandra Gemma, Stefania Butini, Margherita Brindisi, Bhupendra P Joshi, Giuseppe Campiani, Caterina Fattorusso, Marco Persico, Emmanuele Crespan, Reynel Cancio, Silvio Spadari, Ulrich HĂĽbscher, Giovanni Maga | Selective targeting of the HIV-1 reve... | |
| 2008 | Mitsuki Naganuma, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | 1-deoxyrubralactone, a novel specific... | |
| 2008 | Jiaping Lai, Jun Wang, Zongwei Cai | Nucleoside reverse transcriptase inhi... | |
| 2008 | Anna-Maria Monforte, Angela Rao, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Maria Letizia Barreca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Novel N1-substituted 1,3-dihydro-2H-b... | |
| 2008 | Alberta Samuele, Marcella Facchini, Dante Rotili, Antonello Mai, Marino Artico, Mercedes Armand-Ugón, José A Esté, Giovanni Maga | Substrate-induced stable enzyme-inhib... | |
| 2008 | Julie Lemay, Priscilla Maidou-Peindara, Reynel Cancio, Eric Ennifar, Gaël Coadou, Giovanni Maga, Jean-Christophe Rain, Richard Benarous, Lang Xia Liu | AKAP149 binds to HIV-1 reverse transc... | |
| 2008 | Lu Gao, Mark Nils Hanson, Mini Balakrishnan, Paul L Boyer, Bernard P Roques, Stephen H Hughes, Baek Kim, Robert A Bambara | Apparent defects in processive DNA sy... | |
| 2008 | Jangsuk Oh, Mary Jane McWilliams, John G Julias, Stephen H Hughes | Mutations in the U5 region adjacent t... | |
| 2008 | Guangwei Yang, Jianhong Wang, Yao Cheng, Ginger E Dutschman, Hiromichi Tanaka, Masanori Baba, Yung-Chi Cheng | Mechanism of inhibition of human immu... | |
| 2008 | Joseph David Bauman, Kalyan Das, William C Ho, Mukta Baweja, Daniel M Himmel, Arthur D Clark, Deena A Oren, Paul L Boyer, Stephen H Hughes, Aaron J Shatkin, Edward Arnold | Crystal engineering of HIV-1 reverse ... | RT,All properties |
| 2008 | Ravindra K Rawal, Rajkamal Tripathi, Smitha Kulkarni, R Paranjape, S B Katti, Christophe Pannecouque, Erik De Clercq | 2-(2,6-Dihalo-phenyl)-3-heteroaryl-2-... | |
| 2008 | Jingshan Ren, Phillip P Chamberlain, Anna Stamp, Steven A Short, Kurt L Weaver, Karen R Romines, Richard J Hazen, Andrew Freeman, Robert G Ferris, C Webster Andrews, Lawrence R Boone, Joseph H Chan, David K Stammers | Structural basis for the improved dru... | RT,All properties |
| 2008 | Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Design and synthesis of 2-(2,6-dibrom... | |
| 2008 | Kalyan Das, Joseph David Bauman, Arthur D Clark, Yulia Volovik Frenkel, Paul J Lewi, Aaron J Shatkin, Stephen H Hughes, Edward Arnold | High-resolution structures of HIV-1 r... | RT,All properties |
| 2008 | Krista A Delviks-Frankenberry, Galina N Nikolenko, Paul L Boyer, Stephen H Hughes, John M Coffin, Abhay Jere, Vinay K Pathak | HIV-1 reverse transcriptase connectio... | |
| 2008 | Yongcheng Song, Julian M W Chan, Zev Tovian, Aaron Secrest, Eva Nagy, Kilannin Krysiak, Kyle Bergan, Michael A. Parniak, Eric Oldfield | Bisphosphonate inhibitors of ATP-medi... | |
| 2008 | Scott J Garforth, Michael A. Parniak, Vinayaka R Prasad | Utilization of a deoxynucleoside diph... | |
| 2008 | Tatiana Ilina, Michael A. Parniak | Inhibitors of HIV-1 reverse transcrip... | |
| 2008 | Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2008 | Thomas J Tucker, Sandeep Saggar, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan | The design and synthesis of diaryl et... | RT,All properties |
| 2008 | Zachary K Sweeney, James P Dunn, Yingqian Li, Gabrielle M Heilek, Pete W Dunten, Todd R Elworthy, Xiaochun Han, Seth F Harris, Donald R Hirschfeld, J Heather Hogg, Walter Huber, Ann C Kaiser, Denis J Kertesz, Woongki Kim, Taraneh Mirzadegan, Michael G Roepel, Y David Saito, Tania M P C Silva, Steven Swallow, Jahari L Tracy, Armando Villasenor, Harit Vora, Amy S Zhou, Klaus Klumpp | Discovery and optimization of pyridaz... | RT,All properties |
| 2008 | Peng Zhan, Xinyong Liu, Yuan Cao, Yan Wang, Christophe Pannecouque, Erik De Clercq | 1,2,3-Thiadiazole thioacetanilides as... | |
| 2008 | Roger G Ptak, Philippe A Gallay, Dirk Jochmans, Andrew P Halestrap, Urs T Ruegg, Luke A Pallansch, Michael D Bobardt, Marie-Pierre P De BĂ©thune, Johan Neyts, Erik De Clercq, Jean-Maurice Dumont, Pietro Scalfaro, Kamel Besseghir, Roland M Wenger, Brigitte Rosenwirth | Inhibition of human immunodeficiency ... | |
| 2008 | Thorsten A Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty, Albert C Liclican, Damian J McColl, Neil H Squires, Eric B Lansdon | Triazole derivatives as non-nucleosid... | RT,All properties |
| 2008 | Michaela Wendeler, Hsiu-Fang Lee, Alun Bermingham, Jennifer T Miller, Oleg Chertov, Marion K Bona, Noel S Baichoo, Maryam Ehteshami, John A Beutler, Barry R O'Keefe, Matthias Götte, Mamuka Kvaratskhelia, Stuart F J Le Grice | Vinylogous ureas as a novel class of ... | |
| 2008 | Chong Fang, Joseph David Bauman, Kalyan Das, Amanda Remorino, Edward Arnold, Robin M Hochstrasser | Two-dimensional infrared spectra reve... | |
| 2008 | Patrick P Lestienne, François Boudsocq, Jacques E Bonnet | Initiation of DNA replication by a th... | |
| 2008 | Zhengqiang Wang, Robert Vince | Design and synthesis of dual inhibito... | |
| 2008 | Maryam Ehteshami, Greg L Beilhartz, Brian J Scarth, Egor P Tchesnokov, Suzanne McCormick, Brian Wynhoven, P Richard Harrigan, Matthias Götte | Connection domain mutations N348I and... | |
| 2008 | Maryam Ehteshami, Brian J Scarth, Egor P Tchesnokov, Chandravanu Dash, Stuart F J Le Grice, Sabine Hallenberger, Dirk Jochmans, Matthias Götte | Mutations M184V and Y115F in HIV-1 re... | |
| 2008 | Atsushi Kawamoto, Eiichi N Kodama, Stefan G Sarafianos, Yasuko Sakagami, Satoru Kohgo, Kenji Kitano, Noriyuki Ashida, Yuko Iwai, Hiroyuki Hayakawa, Hirotomo Nakata, Hiroyuki Mitsuya, Edward Arnold, Masao Matsuoka | 2'-deoxy-4'-C-ethynyl-2-halo-adenosin... | |
| 2008 | Thomas J Tucker, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, John C Reid, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan | Discovery of 3-{5-[(6-amino-1H-pyrazo... | RT,All properties |
| 2008 | Atsuko Hachiya, Eiichi N Kodama, Stefan G Sarafianos, Matthew M Schuckmann, Yasuko Sakagami, Masao Matsuoka, Masafumi Takiguchi, Hiroyuki Gatanaga, Shinichi Oka | Amino acid mutation N348I in the conn... | |
| 2008 | Marco Radi, Chiara Falciani, Lorenzo Contemori, Elena Petricci, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Montserrat Terrazas, Marinunzia Castria, Andrea Togninelli, José A Esté, Imma Clotet-Codina, Mercedes Armand-Ugón, Maurizio Botta | A multidisciplinary approach for the ... | |
| 2007 | Paul L Boyer, Carolyn R Stenbak, David Hoberman, Maxine L Linial, Stephen H Hughes | In vitro fidelity of the prototype pr... | Full length or truncated,Frameshift Error Rate,Nucleotide Substitution Rate,Overall Error Rate,All properties |
| 2007 | Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, David Moore, Benita Yip, Evan Wood, Julio S G Montaner | Continued improvement in survival amo... | |
| 2007 | Zabrina L Brumme, Chanson J Brumme, Celia K S Chui, Theresa Mo, Brian Wynhoven, Conan K Woods, Bethany M Henrick, Robert S Hogg, Julio S G Montaner, P Richard Harrigan | Effects of human leukocyte antigen cl... | |
| 2007 | Matthew D Cullen, Bo-Liang Deng, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis and biological evaluation o... | |
| 2007 | Andrew J Low, Winnie W Y Dong, Dennison Chan, Tobias Sing, Ronald Swanstrom, Mark Jensen, Satish Pillai, Benjamin Good, P Richard Harrigan | Current V3 genotyping algorithms are ... | |
| 2007 | Lei Ji, Fen-Er Chen, Bin Xie, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV activity evalu... | |
| 2007 | Celia K S Chui, Zabrina L Brumme, Chanson J Brumme, Benita Yip, Elizabeth J Phillips, Julio S G Montaner, P Richard Harrigan | A simple screening approach to reduce... | |
| 2007 | Tokumi Maruyama, Yosuke Demizu, Shigetada Kozai, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq | Antiviral activity of 3-(3,5-dimethyl... | |
| 2007 | Lingjie Liao, Hui Xing, Xincang Li, Yuhua Ruan, Yongqing Zhang, Guangming Qin, Yiming Shao | Genotypic analysis of the protease an... | |
| 2007 | Fernando A Frankel, Dimitrios Coutsinos, Hongtao Xu, Mark A. Wainberg | Kinetics of inhibition of HIV type 1 ... | |
| 2007 | Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh, Eiichi N Kodama, Guangwei Yang, Christopher M Bailey, Satoru Kohgo, Hiroyuki Hayakawa, Masao Matsuoka, Karen S Anderson, Yung-Chi Cheng, Hiroyuki Mitsuya | Activity against human immunodeficien... | |
| 2007 | Dirk Daelemans, Richard Lu, Erik De Clercq, Alan Engelman | Characterization of a replication-com... | |
| 2007 | Kalyan Das, Stefan G Sarafianos, Arthur D Clark, Paul L Boyer, Stephen H Hughes, Edward Arnold | Crystal structures of clinically rele... | |
| 2007 | Clara E Cases-González, Sandra Franco, Miguel Angel MartĂnez, L MenĂ©ndez-Arias | Mutational patterns associated with t... | |
| 2007 | Jianbin Wang, H X Wang, T B Ng | A peptide with HIV-1 reverse transcri... | |
| 2007 | Michael G Thomas, Giovanni Maga, Jean-François Mouscadet, Nicola M Howarth | Investigation of novel lipid-function... | |
| 2007 | Krista A Delviks-Frankenberry, Galina N Nikolenko, Rebekah Barr, Vinay K Pathak | Mutations in human immunodeficiency v... | |
| 2007 | Adrian S Ray, Joy Y Feng, Eisuke Murakami, Chung K Chu, Raymond F Schinazi, Karen S Anderson | Interaction of 2'-deoxyguanosine trip... | |
| 2007 | Paul L Boyer, John G Julias, Zandrea Ambrose, Maqbool A Siddiqui, Victor E Marquez, Stephen H Hughes | The nucleoside analogs 4'C-methyl thy... | |
| 2007 | Marleen C D G Huigen, Loek de Graaf, Dirk Eggink, Rob Schuurman, Viktor MĂĽller, Anna Stamp, David K Stammers, Charles A B Boucher, Monique Nijhuis | Evolution of a novel 5-amino-acid ins... | |
| 2007 | J Scott Daniels, Robert Espina, Kevin Cao, Haodan Yuan, Jianrong Lin, Sharon Diamond, Barry Johnson, James Rodgers, Shimoga Prakash, Steve Unger, David Christ, Gerald Miwa, Liang-Shang Gan, Abdul Mutlib | Species-specific, P450- and sulfotran... | |
| 2007 | Kassim F Adebambo, Samantha Zanoli, Michael G Thomas, Reynel Cancio, Nicola M Howarth, Giovanni Maga | N2-benzyloxycarbonylguan-9-yl acetic ... | |
| 2007 | George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Matthias Gotte, Janice D Pata, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice | Investigating the "steric gate" of hu... | |
| 2007 | Hikaru Yamanaka, Hiroyuki Gatanaga, Pope Kosalaraksa, Saori Matsuoka-Aizawa, Tomonori Takahashi, Seisuke Kimura, Shinichi Oka | Novel mutation of human DNA polymeras... | |
| 2007 | Galina N Nikolenko, Krista A Delviks-Frankenberry, Sarah Palmer, Frank Maldarelli, Matthew J Fivash, John M Coffin, Vinay K Pathak | Mutations in the connection domain of... | |
| 2007 | Silvia Bertagnolio, Luis Soto-Ramirez, Richard Pilon, Roberto Rodriguez, Monica Viveros, Luis Fuentes, P Richard Harrigan, Theresa Mo, Don Sutherland, Paul Sandstrom | HIV-1 drug resistance surveillance us... | |
| 2007 | Katharina Skrabal, Andrew J Low, Winnie W Y Dong, Tobias Sing, Peter K Cheung, Fabrizio Mammano, P Richard Harrigan | Determining human immunodeficiency vi... | |
| 2007 | Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia K S Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P Richard Harrigan | Evidence of differential HLA class I-... | |
| 2007 | Bruno Marchand, Kirsten L White, John K Ly, Nicolas A Margot, Ruth Wang, Martin J McDermott, Michael D Miller, Matthias Götte | Effects of the translocation status o... | |
| 2007 | M R Loutfy, J M Raboud, J S G Montaner, T Antoniou, Brian Wynhoven, F Smaill, D Rouleau, J Gill, W Schlech, Zabrina L Brumme, Theresa Mo, K Gough, A Rachlis, P Richard Harrigan, S L Walmsley | Assay of HIV gp41 amino acid sequence... | |
| 2007 | Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, Joseph H Chan, Jörg-Peter Kleim, David K Stammers | Relationship of potency and resilienc... | RT,All properties |
| 2007 | Shinji Kamisuki, Chisato Ishimaru, Kadohiro Onoda, Isoko Kuriyama, Noriko Ida, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Nodulisporol and Nodulisporone, novel... | |
| 2007 | Bruno Marchand, Egor P Tchesnokov, Matthias Götte | The pyrophosphate analogue foscarnet ... | RT,All properties |
| 2007 | P Richard Harrigan, Theresa Mo, Jennifer Hirsch, Zabrina L Brumme, Paula McKenna, Lee Bacheler | A 21-base pair insertion/duplication ... | |
| 2007 | Guangwei Yang, Ginger E Dutschman, Chuan-Jen Wang, Hiromichi Tanaka, Masanori Baba, Karen S Anderson, Yung-Chi Cheng | Highly selective action of triphospha... | |
| 2007 | Chanson J Brumme, P Richard Harrigan, Emma C Preston, Winnie W Y Dong, Brian Wynhoven, Carol Murphy, Julio S G Montaner | Transmission of drug-resistant HIV-1 ... | |
| 2007 | L W Y Tam, Robert S Hogg, Benita Yip, J S G Montaner, P Richard Harrigan, Chanson J Brumme | Performance of a World Health Organiz... | |
| 2007 | Dirk Eggink, Marleen C D G Huigen, Charles A B Boucher, Matthias Götte, Monique Nijhuis | Insertions in the beta3-beta4 loop of... | |
| 2007 | Takeshi Sakamoto, Matthew D Cullen, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis and anti-HIV activity of ne... | |
| 2007 | Jan Balzarini, Barbara Orzeszko, Jan K Maurin, Andrzej Orzeszko | Synthesis and anti-HIV studies of 2-a... | |
| 2007 | Sonia de Castro, Graziela Andrei, Robert Snoeck, Jan Balzarini, MarĂa-JosĂ© Camarasa, Sonsoles Velázquez | Novel non-nucleoside human cytomegalo... | |
| 2007 | Giovanni Maga, Marco Radi, Samantha Zanoli, Fabrizio Manetti, Reynel Cancio, Ulrich HĂĽbscher, Silvio Spadari, Chiara Falciani, Montserrat Terrazas, Jaume Vilarrasa, Maurizio Botta | Discovery of non-nucleoside inhibitor... | |
| 2007 | Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna-Maria Monforte, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Alba Chimirri | Discovery of novel benzimidazolones a... | |
| 2007 | Lei Ji, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV-1 activity eva... | |
| 2007 | Alok Mulky, B Christie Vu, Joan A Conway, Stephen H Hughes, John C Kappes | Analysis of amino acids in the beta7-... | |
| 2007 | Tobias Sing, Andrew J Low, Niko Beerenwinkel, Oliver Sander, Peter K Cheung, Francisco S Domingues, Joachim Büch, Martin Däumer, Rolf Kaiser, Thomas Lengauer, P Richard Harrigan | Predicting HIV coreceptor usage on th... | |
| 2007 | Elizabeth J Phillips, Sonia Gutiérrez, Natalie Jahnke, Benita Yip, Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, Julio S G Montaner | Determinants of nevirapine hypersensi... | |
| 2007 | Soo-Huey Yap, Chih-Wei Sheen, Jonathan Fahey, Mark Zanin, David Tyssen, Viviane Dias Lima, Brian Wynhoven, Michael Kuiper, Nicolas Sluis-Cremer, P Richard Harrigan, Gilda Tachedjian | N348I in the connection domain of HIV... | RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Storage requirements,RNase H,All properties |
| 2007 | Fernando A Frankel, CĂ©dric F Invernizzi, Maureen Oliveira, Mark A. Wainberg | Diminished efficiency of HIV-1 revers... | |
| 2007 | Matthias Götte | Should we include connection domain m... | |
| 2007 | Jianing Wang, Yunho Jin, Kimberly L Rapp, Raymond F Schinazi, Chung K Chu | D- and L-2',3'-didehydro-2',3'-dideox... | |
| 2007 | Marshall L Morningstar, Thomas Roth, David W Farnsworth, Marilyn B Kroeger Smith, Karen M Watson, Robert W Buckheit, Kalyan Das, Weiming Zhang, Edward Arnold, John G Julias, Stephen H Hughes, Christopher J Michejda | Synthesis, biological activity, and c... | |
| 2007 | Zhengqiang Wang, Eric M Bennett, Daniel J Wilson, Christine E Salomon, Robert Vince | Rationally designed dual inhibitors o... | |
| 2007 | Yazan El Safadi, Valérie Vivet-Boudou, Roland Marquet | HIV-1 reverse transcriptase inhibitors. | RT,All properties |
| 2007 | Jingde Wu, Xinyong Liu, Xianchao Cheng, Yuan Cao, Defeng Wang, Zhongjie Li, Wenfang Xu, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq | Synthesis of novel derivatives of 4-a... | |
| 2007 | Ravindra K Rawal, Raj Kamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Synthesis and biological evaluation o... | |
| 2007 | Stefania Paolucci, Fausto Baldanti, Giulia Campanini, Reynel Cancio, Amalia Belfiore, Giovanni Maga, Giuseppe Gerna | NNRTI-selected mutations at codon 190... | |
| 2007 | Giuseppe La Regina, Antonio Coluccia, Francesco Piscitelli, Alberto Bergamini, Anna Sinistro, Antonella Cavazza, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Ettore Novellino, Marino Artico, Romano Silvestri | Indolyl aryl sulfones as HIV-1 non-nu... | |
| 2007 | William C Drosopoulos, Vinayaka R Prasad | The active site residue Valine 867 in... | |
| 2007 | Christian Castro, Eric D Smidansky, Kenneth R Maksimchuk, Jamie J Arnold, Victoria S Korneeva, Matthias Götte, William H Konigsberg, Craig E Cameron | Two proton transfers in the transitio... | |
| 2007 | Scott J Garforth, Tae Woo Kim, Michael A. Parniak, Eric T Kool, Vinayaka R Prasad | Site-directed mutagenesis in the fing... | |
| 2007 | Matthias Götte | Mechanisms of resistance associated w... | |
| 2007 | Naoko Iwata, Hiroaki Yoshida, Minoru Tobiume, Fumiko Ono, Takuya Shimazaki, Tetsutaro Sata, Noriko Nakajima | Simian fetal brain progenitor cells f... | |
| 2007 | Kristel Van Laethem, Christophe Pannecouque, Anne-Mieke Vandamme | Mutations at 65 and 70 within the con... | |
| 2007 | Qianwei Han, Stefan G Sarafianos, Edward Arnold, Michael A. Parniak, Barbara L Gaffney, Roger A Jones | Synthesis of AZTpSpCX2ppSA and AZTpSp... | |
| 2007 | Wei-Hao Liao, Kuo-Jung Huang, Yu-Fen Chang, Shiu-Mei Wang, Ying-Tzu Tseng, Chien-Cheng Chiang, Jaang-Jiun Wang, Chin-Tien Wang | Incorporation of human immunodeficien... | |
| 2007 | Reynel Cancio, Antonello Mai, Dante Rotili, Marino Artico, Gianluca Sbardella, Imma Clotet-Codina, José A Esté, Emmanuele Crespan, Samantha Zanoli, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Slow-, tight-binding HIV-1 reverse tr... | |
| 2007 | Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J Low, Peter K Cheung, P Richard Harrigan, Thomas Lengauer, Francisco S Domingues | Structural descriptors of gp120 V3 lo... | |
| 2007 | Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Synthesis and evaluation of 2-(2,6-di... | |
| 2007 | Erik De Clercq | Anti-HIV drugs. | |
| 2007 | Sanjeewa Dharmasena, Zita Pongracz, Edward Arnold, Stefan G Sarafianos, Michael A. Parniak | 3'-Azido-3'-deoxythymidine-(5')-tetra... | RT,All properties |
| 2006 | Tokumi Maruyama, Shigetada Kozai, Yosuke Demizu, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq | Synthesis and anti-HIV-1 and anti-HCM... | |
| 2006 | Daniel M Himmel, Stefan G Sarafianos, Sanjeewa Dharmasena, Mohammed M Hossain, Kessler McCoy-Simandle, Tatiana Ilina, Arthur D Clark, Jennifer L Knight, John G Julias, Patrick K Clark, Karsten Krogh-Jespersen, Ronald M Levy, Stephen H Hughes, Michael A. Parniak, Edward Arnold | HIV-1 reverse transcriptase structure... | RT,RNase H,All properties |
| 2006 | Najim A Al-Masoudi, Yaseen A Al-Soud, Aris Kalogerakis, Christophe Pannecouque, Erik De Clercq | Nitroimidazoles, part 2: Synthesis, a... | |
| 2006 | Varuni K Jamburuthugoda, Pauline Chugh, Baek Kim | Modification of human immunodeficienc... | |
| 2006 | Monica E Hamburgh, Kenneth A Curr, Melissa Monaghan, Vasudev R Rao, Snehlata Tripathi, Bradley D Preston, Stefan G Sarafianos, Edward Arnold, Thomas Darden, Vinayaka R Prasad | Structural determinants of slippage-m... | |
| 2006 | Antonio Lavecchia, Roberta Costi, Marino Artico, Gaetano Miele, Ettore Novellino, Alberto Bergamini, Emmanuele Crespan, Giovanni Maga, Roberto Di Santo | Arylthiopyrrole (AThP) derivatives as... | |
| 2006 | Nicolas Sluis-Cremer, Noureddine Hamamouch, Ana San FĂ©lix, Sonsoles Velazquez, Jan Balzarini, MarĂa-JosĂ© Camarasa | Structure-activity relationships of [... | |
| 2006 | Hiroshi Ohrui, Satoru Kohgo, Hiroyuki Hayakawa, Eiichi N Kodama, Masao Matsuoka, Tomohiro Nakata, Hiroyuki Mitsuya | 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosi... | RT,All properties |
| 2006 | N Machouf, R Thomas, V K Nguyen, B Trottier, M R Boulassel, Mark A. Wainberg, Jean-Pierre Routy | Effects of drug resistance on viral l... | |
| 2006 | Carlos Cruchaga, Elena AnsĂł, Ana Rouzaut, Juan J MartĂnez-Irujo | Selective excision of chain-terminati... | |
| 2006 | MarĂa-JosĂ© Camarasa, Sonsoles Velázquez, Ana San-FĂ©lix, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Federico Gago | Dimerization inhibitors of HIV-1 reve... | |
| 2006 | Klaus Klumpp, Tara Mirzadegan | Recent progress in the design of smal... | |
| 2006 | Kirsten L White, James M Chen, Joy Y Feng, Nicolas A Margot, John K Ly, Adrian S Ray, Holly L Macarthur, Martin J McDermott, S Swaminathan, Michael D Miller | The K65R reverse transcriptase mutati... | |
| 2006 | Bo-Liang Deng, Matthew D Cullen, Zhigang Zhou, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman | Synthesis and anti-HIV activity of ne... | |
| 2006 | Carrie Dykes, Jiong Wang, Xia Jin, Vicente Planelles, Dong Sung An, Amanda Tallo, Yangxin Huang, Hulin Wu, Lisa M Demeter | Evaluation of a multiple-cycle, recom... | |
| 2006 | Matthias Götte | Effects of nucleotides and nucleotide... | RT,All properties |
| 2006 | Paul L Boyer, Stefan G Sarafianos, Patrick K Clark, Edward Arnold, Stephen H Hughes | Why do HIV-1 and HIV-2 use different ... | |
| 2006 | Enzo Tramontano | HIV-1 RNase H: recent progress in an ... | |
| 2006 | Sarit Aviel-Ronen, Chang Qi Zhu, Bradley P Coe, Ni Liu, Spencer K Watson, Wan L Lam, Ming Sound Tsao | Large fragment Bst DNA polymerase for... | |
| 2006 | CF Perno, Valentina Svicher, Dominique Schols, Michela Pollicita, Jan Balzarini, Stefano Aquaro | Therapeutic strategies towards HIV-1 ... | |
| 2006 | MarĂa-JosĂ© Camarasa, Sonsoles Velázquez, Ana San-FĂ©lix, MarĂa-JesĂşs PĂ©rez-PĂ©rez, MarĂa-Cruz Bonache, Sonia de Castro | TSAO derivatives, inhibitors of HIV-1... | |
| 2006 | Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Combining mutations in HIV-1 reverse ... | |
| 2006 | Frank Goebel, Alexy Yakovlev, Anton L Pozniak, Elena Vinogradova, Griet Boogaerts, Richard Hoetelmans, Marie-Pierre P De BĂ©thune, Monika Peeters, Brian Woodfall | Short-term antiviral activity of TMC2... | |
| 2006 | Lei Ji, Fen-Er Chen, Xiao-Qing Feng, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2006 | Dirk Jochmans, Jérôme Deval, Bart Kesteleyn, Herwig Van Marck, Eva Bettens, Inky De Baere, Pascale Dehertogh, Tania Ivens, Marcia Van Ginderen, Bertrand Van Schoubroeck, Maryam Ehteshami, Piet Wigerinck, Matthias Götte, Kurt Hertogs | Indolopyridones inhibit human immunod... | RT,All properties |
| 2006 | Zandrea Ambrose, John G Julias, Paul L Boyer, Vineet N Kewalramani, Stephen H Hughes | The level of reverse transcriptase (R... | |
| 2006 | Jingshan Ren, Charles E Nichols, Anna Stamp, Phillip P Chamberlain, Robert G Ferris, Kurt L Weaver, Steven A Short, David K Stammers | Structural insights into mechanisms o... | |
| 2006 | Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong | Novel nonnucleoside inhibitors that s... | |
| 2006 | Valentina Svicher, Tobias Sing, Maria Mercedes Santoro, Federica Forbici, Fátima RodrĂguez-Barrios, Ada Bertoli, Niko Beerenwinkel, Maria Concetta Bellocchi, Federigo Gago, Antonella d'Arminio Monforte, Andrea Antinori, Thomas Lengauer, F Ceccherini-Silberstein, CF Perno | Involvement of novel human immunodefi... | |
| 2006 | Roberto Di Santo, Roberta Costi, Marino Artico, Gaetano Miele, Antonio Lavecchia, Ettore Novellino, Alberto Bergamini, Reynel Cancio, Giovanni Maga | Arylthiopyrrole (AThP) derivatives as... | |
| 2006 | Roberto Di Santo, Roberta Costi, Marino Artico, Rino Ragno, Antonio Lavecchia, Ettore Novellino, Enrico Gavuzzo, Francesco La Torre, Roberto Cirilli, Reynel Cancio, Giovanni Maga | Design, synthesis, biological evaluat... | |
| 2006 | Gabriella De Martino, Giuseppe La Regina, Rino Ragno, Antonio Coluccia, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri | Indolyl aryl sulphones as HIV-1 non-n... | |
| 2006 | Christine E Koval, Carrie Dykes, Jiong Wang, Lisa M Demeter | Relative replication fitness of efavi... | |
| 2006 | Jiong Wang, Carrie Dykes, R A Domaoal, Christine E Koval, R A Bambara, Lisa M Demeter | The HIV-1 reverse transcriptase mutan... | |
| 2005 | Jan Heeres, Marc R De Jonge, Lucien M H Koymans, Frits F D Daeyaert, Maarten H Vinkers, Koen J A Van Aken, Edward Arnold, Kalyan Das, Amuri Kilonda, Georges J Hoornaert, Frans Compernolle, Marek Cegla, Rasha A Azzam, Koen Andries, Marie-Pierre P De BĂ©thune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Paul A J Janssen | Design, synthesis, and SAR of a novel... | |
| 2005 | Rienk E Jeeninga, Barbara Jan, Birgit van der Linden, Henk van den Berg, Ben Berkhout | Construction of a minimal HIV-1 varia... | |
| 2005 | Kirsten L White, Nicolas A Margot, John K Ly, James M Chen, Adrian S Ray, Martina Pavelko, Ruth Wang, Martin J McDermott, S Swaminathan, Michael D Miller | A combination of decreased NRTI incor... | |
| 2005 | Scott R Budihas, Inna Gorshkova, Sergei A Gaidamakov, Antony Wamiru, Marion K Bona, Michael A. Parniak, Robert J Crouch, James B McMahon, John A Beutler, Stuart F J Le Grice | Selective inhibition of HIV-1 reverse... | |
| 2005 | Micha Nethe, Ben Berkhout, Antoinette C van der Kuyl | Retroviral superinfection resistance. | |
| 2005 | Luis R Miranda, Matthias Götte, Fei Liang, Daniel R Kuritzkes | The L74V mutation in human immunodefi... | |
| 2005 | Lia van der Hoek, Nicole Back, Maarten F Jebbink, Anthony de Ronde, Margreet Bakker, Suzanne Jurriaans, Peter Reiss, Neil Parkin, Ben Berkhout | Increased multinucleoside drug resist... | |
| 2005 | Ben Berkhout, Anthony de Ronde, Lia van der Hoek | Aggressive HIV-1? | |
| 2005 | Ronald B Geskus, Laurence Meyer, Jean-Baptiste Hubert, Hanneke Schuitemaker, Ben Berkhout, Christine Rouzioux, Ioannis D Theodorou, Jean-François Delfraissy, Maria Prins, Roel A Coutinho | Causal pathways of the effects of age... | |
| 2005 | Daniel M Himmel, Kalyan Das, Arthur D Clark, Stephen H Hughes, Abdellah Benjahad, Said Oumouch, JĂ©rĂ´me Guillemont, Sophie Coupa, Alain Poncelet, Imre Csoka, Christophe Meyer, Koen Andries, Chi Hung Nguyen, David S Grierson, Edward Arnold | Crystal structures for HIV-1 reverse ... | RT,Associated condition,All properties |
| 2005 | Erik De Clercq | Emerging anti-HIV drugs. | |
| 2005 | Tongfei Wu, Matheus Froeyen, Veerle Kempeneers, Christophe Pannecouque, Jing Wang, Roger Busson, Erik De Clercq, Piet Herdewijn | Deoxythreosyl phosphonate nucleosides... | |
| 2005 | Abdellah Benjahad, Martine Croisy, Claude Monneret, Emile Bisagni, Dominique Mabire, Sophie Coupa, Alain Poncelet, Imre Csoka, JĂ©rĂ´me Guillemont, Christophe Meyer, Koen Andries, Rudi Pauwels, Marie-Pierre P De BĂ©thune, Daniel M Himmel, Kalyan Das, Edward Arnold, Chi Hung Nguyen, David S Grierson | 4-Benzyl and 4-benzoyl-3-dimethylamin... | |
| 2005 | Kalyan Das, Paul J Lewi, Stephen H Hughes, Edward Arnold | Crystallography and the design of ant... | |
| 2005 | Joël Didierjean, Catherine Isel, Flore Querré, Jean-François Mouscadet, Anne-Marie Aubertin, Jean-Yves Valnot, Serge R Piettre, Roland Marquet | Inhibition of human immunodeficiency ... | |
| 2005 | Caterina Fattorusso, Sandra Gemma, Stefania Butini, Paul Huleatt, Bruno Catalanotti, Marco Persico, Meri De Angelis, Isabella Fiorini, Vito Nacci, Anna Ramunno, Manuela Rodriquez, Giovanni Greco, Ettore Novellino, Alberto Bergamini, Stefano Marini, Massimo Coletta, Giovanni Maga, Silvio Spadari, Giuseppe Campiani | Specific targeting highly conserved r... | |
| 2005 | Antonello Mai, Marino Artico, Rino Ragno, Gianluca Sbardella, Silvio Massa, Chiara Musiu, Massimo Mura, Flavia Marturana, Alessandra Cadeddu, Giovanni Maga, Paolo La Colla | 5-Alkyl-2-alkylamino-6-(2,6-difluorop... | |
| 2005 | Emmanuele Crespan, Giada A Locatelli, Reynel Cancio, Ulrich HĂĽbscher, Silvio Spadari, Giovanni Maga | Drug resistance mutations in the nucl... | |
| 2005 | Andrew R Zolopa, Laura C Lazzeroni, Alex Rinehart, Françoise Brun Vezinet, François Clavel, Ann Collier, Brian Conway, Roy M Gulick, Mark Holodniy, CF Perno, Robert W Shafer, Douglas D Richman, Mark A. Wainberg, Daniel R Kuritzkes | Accuracy, precision, and consistency ... | |
| 2005 | Yaofeng Zhao, Yang Jin, Jing-Houng Wang, Rui-Rui Wang, Liu-Meng Yang, Wen-Hui Lee, Yong-Tang Zheng, Yongqing Zhang | A novel heme-containing protein with ... | |
| 2005 | Mark A. Wainberg, James P C Sawyer, Julio S G Montaner, Robert L Murphy, Daniel R Kuritzkes, Francois Raffi | Challenges for the clinical developme... | |
| 2005 | Dan Turner, Bluma G Brenner, Daniela D Moisi, Chen Liang, Mark A. Wainberg | Substitutions in the Reverse Transcri... | |
| 2005 | Bo-Liang Deng, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman | Synthesis, anti-HIV activity, and met... | |
| 2005 | Cathryn A Shaw-Reid, Bradley Feuston, Vandna Munshi, Krista Getty, Julie Krueger, Daria J Hazuda, Michael A. Parniak, Michael D Miller, Dale Lewis | Dissecting the effects of DNA polymer... | |
| 2005 | Guang-Fu Sun, Yun-Yan Kuang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Non-nucleoside HIV reverse transcript... | |
| 2005 | Albert Nguyen Van Nhien, Cyrille Tomassi, Christophe Len, José Luis Marco-Contelles, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Denis Postel | First synthesis and evaluation of the... | |
| 2005 | Joeri Auwerx, Fátima RodrĂguez-Barrios, F Ceccherini-Silberstein, Ana San-FĂ©lix, Sonsoles Velázquez, Erik De Clercq, MarĂa-JosĂ© Camarasa, CF Perno, Federico Gago, Jan Balzarini | The role of Thr139 in the human immun... | |
| 2005 | Fátima RodrĂguez-Barrios, Jan Balzarini, Federico Gago | The molecular basis of resilience to ... | |
| 2005 | Ariel Roldan, Otis U Warren, Rodney S Russell, Chen Liang, Mark A. Wainberg | A HIV-1 minimal gag protein is superi... | |
| 2005 | Daniel Summerer, Andreas Marx | 4'C-ethynyl-thymidine acts as a chain... | |
| 2005 | Michael E Abram, Michael A. Parniak | Virion instability of human immunodef... | |
| 2005 | MarĂa-JosĂ© Camarasa, Sonsoles Velázquez, Ana San-FĂ©lix, MarĂa-JesĂşs PĂ©rez-PĂ©rez | TSAO derivatives the first non-peptid... | |
| 2005 | Darwin J Operario, Holly M Reynolds, Baek Kim | Comparison of DNA polymerase activiti... | Molecular Weight,Overall Error Rate,All properties |
| 2005 | Gabriella De Martino, Giuseppe La Regina, Alessandra Di Pasquali, Rino Ragno, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri | Novel 1-[2-(diarylmethoxy)ethyl]-2-me... | |
| 2005 | Paul A J Janssen, Paul J Lewi, Edward Arnold, Frits F D Daeyaert, Marc R De Jonge, Jan Heeres, Luc Koymans, Maarten H Vinkers, JĂ©rĂ´me Guillemont, Elisabeth Pasquier, Michael Kukla, Don Ludovici, Koen Andries, Marie-Pierre P De BĂ©thune, Rudi Pauwels, Kalyan Das, Arthur D Clark, Yulia Volovik Frenkel, Stephen H Hughes, Bart Medaer, Fons De Knaep, Hilde Bohets, Fred De Clerck, Ann Lampo, Peter Williams, Paul Stoffels | In search of a novel anti-HIV drug: m... | |
| 2005 | Jan Balzarini, Kristel Van Laethem, Sigrid Hatse, Matheus Froeyen, Els Van Damme, Anders Bolmstedt, Willy Peumans, Erik De Clercq, Dominique Schols | Marked depletion of glycosylation sit... | |
| 2005 | Junmei Wang, Xinshan Kang, Irwin D Kuntz, Peter A Kollman | Hierarchical database screenings for ... | |
| 2005 | Guang-Fu Sun, Xu-Xiang Chen, Fen-Er Chen, Yue-Ping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse-transcrip... | |
| 2005 | Jan Balzarini, Miguel Stevens, Erik De Clercq, Dominique Schols, Christophe Pannecouque | Pyridine N-oxide derivatives: unusual... | |
| 2005 | Emmanuele Crespan, Samantha Zanoli, Anastasiya Khandazhinskaya, Igor V Shevelev, Maxim Jasko, Ludmila Alexandrova, Marina Kukhanova, Giuseppina Blanca, Giuseppe Villani, Ulrich HĂĽbscher, Silvio Spadari, Giovanni Maga | Incorporation of non-nucleoside triph... | |
| 2005 | Joeri Auwerx, Joke Van Nieuwenhove, Fátima RodrĂguez-Barrios, Sonia de Castro, Sonsoles Velázquez, F Ceccherini-Silberstein, Erik De Clercq, MarĂa-JosĂ© Camarasa, CF Perno, Federico Gago, Jan Balzarini | The N137 and P140 amino acids in the ... | |
| 2005 | Hong Li, Zhengqiang Wang, Wei-guo Cui, Yan Liang, Tian-yi Xin, Jinming Li | [Study on adherence and interrelated ... | |
| 2005 | Hong Zang, Thomas M Harris, F Peter Guengerich | Kinetics of nucleotide incorporation ... | |
| 2005 | Hong Zang, Thomas M Harris, F Peter Guengerich | Kinetics of nucleotide incorporation ... | |
| 2005 | Nicolas Sluis-Cremer, Dominique Arion, Urvi Parikh, Dianna Koontz, Raymond F Schinazi, John W Mellors, Michael A. Parniak | The 3'-azido group is not the primary... | |
| 2005 | Melaku Adal, Workenesh Ayele, Dawit Wolday, Kifle Dagne, Tsehaynesh Messele, Tesfaye Tilahun, Ben Berkhout, Shlomo Mayaan, Georgios Pollakis, Wendelien Dorigo-Zetsma | Evidence of genetic variability of hu... | |
| 2005 | Fernando A Frankel, Bruno Marchand, Dan Turner, Matthias Götte, Mark A. Wainberg | Impaired rescue of chain-terminated D... | |
| 2005 | Johan Vingerhoets, Hilde Azijn, Els Fransen, Inky De Baere, Liesbet Smeulders, Dirk Jochmans, Koen Andries, Rudi Pauwels, Marie-Pierre P De BĂ©thune | TMC125 displays a high genetic barrie... | |
| 2005 | Alok Mulky, Stefan G Sarafianos, Yujiang Jia, Edward Arnold, John C Kappes | Identification of amino acid residues... | |
| 2005 | Dan Turner, Bluma G Brenner, Daniela Mosis, Chen Liang, Mark A. Wainberg | Substitutions in the reverse transcri... | |
| 2005 | Pia S Kivelä, Anneke Krol, Mika O Salminen, Ronald B Geskus, Jukka I Suni, Veli-Jukka Anttila, Kirsi Liitsola, Veera Zetterberg, Frank Miedema, Ben Berkhout, Roel A Coutinho, Matti A Ristola | High plasma HIV load in the CRF01-AE ... | |
| 2005 | Ariel Fernández, Dan S Tawfik, Ben Berkhout, Rogier W Sanders, Andrzej Kloczkowski, Taner Sen, Bob Jernigan | Protein promiscuity: drug resistance ... | |
| 2005 | F Ceccherini-Silberstein, Federico Gago, Maria Mercedes Santoro, Caterina Gori, Valentina Svicher, Fátima RodrĂguez-Barrios, Roberta d'Arrigo, Massimo Ciccozzi, Ada Bertoli, Antonella d'Arminio Monforte, Jan Balzarini, Andrea Antinori, CF Perno | High sequence conservation of human i... | |
| 2005 | Natalia A Lebedeva, T A Seredina, V N Silnikov, T V Abramova, A S Levina, Svetlana N Khodyreva, Nadejda I Rechkunova, Olga I Lavrik | Analysis of interactions of DNA polym... | |
| 2005 | Myriam Witvrouw, Valery Fikkert, Anke Hantson, Christophe Pannecouque, Barry R O'keefe, James McMahon, Leonidas Stamatatos, Erik De Clercq, Anders Bolmstedt | Resistance of human immunodeficiency ... | |
| 2005 | Jan Balzarini, Joeri Auwerx, Fátima RodrĂguez-Barrios, Allel Chedad, Viktor Farkas, F Ceccherini-Silberstein, Carlos GarcĂa-Aparicio, Sonsoles Velázquez, Erik De Clercq, CF Perno, MarĂa-JosĂ© Camarasa, Federico Gago | The amino acid Asn136 in HIV-1 revers... | |
| 2005 | Michael E Ignatov, Anthony J Berdis, Stuart F J Le Grice, Mary D Barkley | Attenuation of DNA replication by HIV... | |
| 2004 | Claudia M D'Abramo, Luciano Cellai, Matthias Götte | Excision of incorporated nucleotide a... | |
| 2004 | Rachelle J Bienstock, Willliam C Copeland | Molecular insights into NRTI inhibiti... | |
| 2004 | George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Kalavathy Sitaraman, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice | Site- and subunit-specific incorporat... | |
| 2004 | Eisuke Murakami, Adrian S Ray, Raymond F Schinazi, Karen S Anderson | Investigating the effects of stereoch... | |
| 2004 | Satoru Kohgo, Kohei Yamada, Kenji Kitano, Yuko Iwai, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui | Design, efficient synthesis, and anti... | |
| 2004 | Zandrea Ambrose, Valerie Boltz, Sarah Palmer, John M Coffin, Stephen H Hughes, Vineet N Kewalramani | In vitro characterization of a simian... | |
| 2004 | John G Julias, Paul L Boyer, Mary Jane McWilliams, W Gregory Alvord, Stephen H Hughes | Mutations at position 184 of human im... | |
| 2004 | A Michael Sismour, Stefan Lutz, Jeong-Ho Park, Michael J Lutz, Paul L Boyer, Stephen H Hughes, Steven A Benner | PCR amplification of DNA containing n... | |
| 2004 | Dan Turner, Bluma G Brenner, Daniela D Moisi, Mervi Detorio, Raymond Cesaire, Takashi Kurimura, Haruyo Mori, Max Essex, Shlomo Maayan, Mark A. Wainberg | Nucleotide and amino acid polymorphis... | |
| 2004 | Giada A Locatelli, Giuseppe Campiani, Reynel Cancio, Elena Morelli, Anna Ramunno, Sandra Gemma, Ulrich HĂĽbscher, Silvio Spadari, Giovanni Maga | Effects of drug resistance mutations ... | |
| 2004 | Stefania Paolucci, Fausto Baldanti, Giovanni Maga, Reynel Cancio, Maurizio Zazzi, Maurizio Zavattoni, Antonella Chiesa, Silvio Spadari, Giuseppe Gerna | Gln145Met/Leu changes in human immuno... | |
| 2004 | Peter R Meyer, Anthony J Smith, Suzanne E Matsuura, Walter A Scott | Effects of primer-template sequence o... | |
| 2004 | Julie Qi Hang, Surendran Rajendran, Yanli Yang, Yingqian Li, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin, Klaus Klumpp | Activity of the isolated HIV RNase H ... | |
| 2004 | Jan Balzarini | Current status of the non-nucleoside ... | |
| 2004 | Steve Tuske, Stefan G Sarafianos, Arthur D Clark, Jianping Ding, Lisa K Naeger, Kirsten L White, Michael D Miller, Craig S Gibbs, Paul L Boyer, Patrick K Clark, Gang Wang, Barbara L Gaffney, Roger A Jones, Donald M Jerina, Stephen H Hughes, Edward Arnold | Structures of HIV-1 RT-DNA complexes ... | |
| 2004 | Louise Z Wang, George L Kenyon, Kenneth A Johnson | Novel mechanism of inhibition of HIV-... | |
| 2004 | Stefan G Sarafianos, Stephen H Hughes, Edward Arnold | Designing anti-AIDS drugs targeting t... | |
| 2004 | Elena N Peletskaya, Alex A Kogon, Steven Tuske, Edward Arnold, Stephen H Hughes | Nonnucleoside inhibitor binding affec... | RT,Associated condition,All properties |
| 2004 | Joeri Auwerx, Miguel Stevens, An R Van Rompay, Louise E Bird, Jingshan Ren, Erik De Clercq, Bo Oberg, David K Stammers, Anna Karlsson, Jan Balzarini | The phenylmethylthiazolylthiourea non... | |
| 2004 | Erik De Clercq | Antiviral drugs in current clinical use. | |
| 2004 | Elisabetta Bulgheroni, Francesco Croce, Paola Citterio, Ottavia Viganò, Raffaella Visonà , Eugenio Sala, Massimo Galli, Stefano Rusconi | Unusual codon 69 insertions: influenc... | |
| 2004 | Erik De Clercq | Non-nucleoside reverse transcriptase ... | |
| 2004 | Michael B Doughty, Karam Aboudehen, Garland Anderson, Ke Li, Bob Moore, Tina Poolson | Side-chain conformational restriction... | |
| 2004 | MarĂa-JosĂ© Camarasa, Ana San-FĂ©lix, Sonsoles Velázquez, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Federico Gago, Jan Balzarini | TSAO compounds: the comprehensive sto... | |
| 2004 | CF Perno, Emanuela Balestra, M Francesconi, D Abdelahad, Raffaele Caliò, Jan Balzarini, Stefano Aquaro | Antiviral profile of HIV inhibitors i... | |
| 2004 | Esther W Hou, Rajendra Prasad, William A Beard, Samuel H Wilson | High-level expression and purificatio... | |
| 2004 | Matthias Götte | Inhibition of HIV-1 reverse transcrip... | |
| 2004 | Lisa F Rezende, Vinayaka R Prasad | Nucleoside-analog resistance mutation... | RT,Associated condition,All properties |
| 2004 | Paul J Lewi, Edward Arnold, Koen Andries, Hilde Bohets, Herman Borghys, Arthur D Clark, Frits F D Daeyaert, Kalyan Das, Marie-Pierre P De Béthune, Marc R De Jonge, Jan Heeres, Luc Koymans, Jos Leempoels, Jef Peeters, Philip Timmerman, Walter Van den Broeck, Frédéric Vanhoutte, Gerben Van't Klooster, Maarten H Vinkers, Yulia Volovik, Paul A J Janssen | Correlations between factors determin... | |
| 2004 | Nicolas Sluis-Cremer, Dominique Arion, Michael E Abram, Michael A. Parniak | Proteolytic processing of an HIV-1 po... | |
| 2004 | Yanping He, Fener Chen, Guangfu Sun, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | 5-Alkyl-2-[(aryl and alkyloxylcarbony... | |
| 2004 | Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna-Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria ZappalĂ | 2-(2,6-Dihalophenyl)-3-(pyrimidin-2-y... | |
| 2004 | Bruno Marchand, Matthias Götte | Impact of the translocational equilib... | |
| 2004 | Yanping He, Fener Chen, Xiongjie Yu, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse transcrip... | |
| 2004 | Florence Doualla-Bell, Simane Gaseitsiwe, Thumbi NdungĂş, Musetsanagepe Modukanele, Trevor Peter, Vladimir Novitsky, Ndwapi Ndwapi, Gaolathe Tendani, Ava Avalos, William Wester, Hermann Bussmann, Peter Cardiello, Richard G Marlink, Howard Moffat, Ibou Thior, Mark A. Wainberg, Max Essex | Mutations and polymorphisms associate... | |
| 2004 | Mark A. Wainberg | The impact of the M184V substitution ... | |
| 2004 | Dan Turner, Bluma G Brenner, Mark A. Wainberg | Relationships among various nucleosid... | |
| 2004 | George R Painter, Merrick R Almond, Shuli Mao, Dennis C Liotta | Biochemical and mechanistic basis for... | RT,Associated condition,All properties |
| 2004 | Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria ZappalĂ | Synthesis of new 2,3-diaryl-1,3-thiaz... | |
| 2004 | Jérôme Deval, Kirsten L White, Michael D Miller, Neil T Parkin, Jérôme Courcambeck, Philippe Halfon, Boulbaba Selmi, Joëlle Boretto, Bruno Canard | Mechanistic basis for reduced viral a... | |
| 2004 | Maqbool A Siddiqui, Stephen H Hughes, Paul L Boyer, Hiroyuki Mitsuya, Que N Van, Clifford George, Stefan G Sarafinanos, Victor E Marquez | A 4'-C-ethynyl-2',3'-dideoxynucleosid... | |
| 2004 | Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Zeev Rosberger, Michel Roger, Mark A. Wainberg | Diminished representation of HIV-1 va... | |
| 2004 | Dan Turner, Ariel Roldan, Bluma G Brenner, Daniela D Moisi, Jean-Pierre Routy, Mark A. Wainberg | Variability in the PR and RT genes of... | |
| 2004 | Joy Y Feng, Eisuke Murakami, Suzana M Zorca, Allison A Johnson, Kenneth A Johnson, Raymond F Schinazi, Phillip A Furman, Karen S Anderson | Relationship between antiviral activi... | |
| 2004 | Giada A Locatelli, Reynel Cancio, Silvio Spadari, Giovanni Maga | HIV-1 reverse transcriptase inhibitor... | |
| 2004 | Reynel Cancio, Silvio Spadari, Giovanni Maga | Vif is an auxiliary factor of the HIV... | |
| 2004 | Joeri Auwerx, Robert Esnouf, Erik De Clercq, Jan Balzarini | Susceptibility of feline immunodefici... | |
| 2004 | Kalyan Das, Arthur D Clark, Paul J Lewi, Jan Heeres, Marc R De Jonge, Lucien M H Koymans, H Maarten Vinkers, Frederik Daeyaert, Donald W Ludovici, Michael J Kukla, Bart De Corte, Robert W Kavash, Chih Y Ho, Hong Ye, Mark A Lichtenstein, Koen Andries, Rudi Pauwels, Marie-Pierre P De BĂ©thune, Paul L Boyer, Patrick K Clark, Stephen H Hughes, Paul A J Janssen, Edward Arnold | Roles of conformational and positiona... | |
| 2004 | Stefan G Sarafianos, Kalyan Das, Stephen H Hughes, Edward Arnold | Taking aim at a moving target: design... | |
| 2004 | Kenji Kitano, Satoru Kohgo, Kohei Yamada, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui | Attempt to reduce cytotoxicity by syn... | |
| 2004 | Myriam Witvrouw, Bénédicte Van Maele, J Vercammen, Anke Hantson, Y Engelborghs, Erik De Clercq, Christophe Pannecouque, Zeger Debyser | Novel inhibitors of HIV-1 integration. | |
| 2004 | King C Chan, Scott R Budihas, Stuart F J Le Grice, Michael A. Parniak, Robert J Crouch, Sergei A Gaidamakov, Haleem J Isaaq, Antony Wamiru, James B McMahon, John A Beutler | A capillary electrophoretic assay for... | |
| 2004 | Debanu Das, Millie M Georgiadis | The crystal structure of the monomeri... | |
| 2004 | Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Marco Petrella, Mark A. Wainberg | Rationale for maintenance of the M184... | |
| 2004 | George A Freeman, C Webster Andrews Iii, Andrew L Hopkins, Gina S Lowell, Lee T Schaller, Jill R Cowan, Stephen S Gonzales, George W Koszalka, Richard J Hazen, Lawrence R Boone, Rob G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, David J Reynolds, John Milton, Jingshan Ren, David I Stuart, David K Stammers, Joseph H Chan | Design of non-nucleoside inhibitors o... | RT,Associated condition,All properties |
| 2004 | Paul L Boyer, Tomozumi Imamichi, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Effects of the Delta67 complex of mut... | |
| 2004 | Koen Andries, Hilde Azijn, Theo Thielemans, Donald W Ludovici, Michael Kukla, Jan Heeres, Paul A J Janssen, Bart De Corte, Johan Vingerhoets, Rudi Pauwels, Marie-Pierre P De BĂ©thune | TMC125, a novel next-generation nonnu... | RT,Associated condition,All properties |
| 2004 | Kirsten L White, James M Chen, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Lisa K Naeger, S Swaminathan, Michael D Miller | Molecular mechanisms of tenofovir res... | |
| 2004 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Effects of mutations in the G tract o... | |
| 2004 | Jérôme Deval, Jean-Marc Navarro, Boulbaba Selmi, Jérôme Courcambeck, Joëlle Boretto, Philippe Halfon, Sarah Garrido-Urbani, Josephine Sire, Bruno Canard | A loss of viral replicative capacity ... | |
| 2004 | Maximilian A Silvestri, Muthukaman Nagarajan, Erik De Clercq, Christophe Pannecouque, Mark Cushman | Design, synthesis, anti-HIV activitie... | |
| 2004 | Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, David K Stammers | Crystal structures of HIV-1 reverse t... | |
| 2004 | Andrew L Hopkins, Jingshan Ren, John Milton, Richard J Hazen, Joseph H Chan, David I Stuart, David K Stammers | Design of non-nucleoside inhibitors o... | RT,Associated condition,All properties |
| 2004 | Alok Mulky, Stefan G Sarafianos, Edward Arnold, Xiaoming Wu, John C Kappes | Subunit-specific analysis of the huma... | |
| 2004 | Jeong-Yun Choi, F Peter Guengerich | Analysis of the effect of bulk at N2-... | |
| 2003 | J Gerardo GarcĂa-Lerma, Hamish MacInnes, Diane Bennett, Patrick Reid, Soumya Nidtha, Hillard Weinstock, Jonathan E Kaplan, Walid Heneine | A novel genetic pathway of human immu... | |
| 2003 | Yudong Quan, Bluma G Brenner, Maureen Oliveira, Mark A. Wainberg | Lamivudine can exert a modest antivir... | |
| 2003 | Martin StĂĽrmer, Schlomo Staszewski, Hans-Wilhelm Doerr, Brendan A Larder, Stuart Bloor, Kurt Hertogs | Correlation of phenotypic zidovudine ... | |
| 2003 | Bluma G Brenner, Dan Turner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Mauricio Carobene, Richard G Marlink, Jonathan Schapiro, Michel Roger, Mark A. Wainberg | A V106M mutation in HIV-1 clade C vir... | |
| 2003 | Joel E Gallant, Peter Z Gerondelis, Mark A. Wainberg, Nancy S Shulman, Richard H Haubrich, Marty St Clair, Ernest R Lanier, Nicholas S Hellmann, Douglas D Richman | Nucleoside and nucleotide analogue re... | RT,Associated condition,All properties |
| 2003 | Lingling Shen, Jianhua Shen, Xiaomin Luo, Feng Cheng, Yechun Xu, Kaixian Chen, Edward Arnold, Jianping Ding, Hualiang Jiang | Steered molecular dynamics simulation... | |
| 2003 | Harold R Lee, Jeremiah Hanes, Kenneth A Johnson | Toxicity of nucleoside analogues used... | |
| 2003 | Marilyn B Kroeger Smith, Brian M Hose, Arie Hawkins, James Lipchock, David W Farnsworth, Robert C Rizzo, Julian Tirado-Rives, Edward Arnold, Weiming Zhang, Stephen H Hughes, William L Jorgensen, Christopher J Michejda, Richard H Smith | Molecular modeling calculations of HI... | |
| 2003 | Peter R Meyer, Suzanne E Matsuura, Dianna Zonarich, Rahul R Chopra, Eric Pendarvis, Holly Z Bazmi, John W Mellors, Walter A Scott | Relationship between 3'-azido-3'-deox... | |
| 2003 | Adrian S Ray, Raymond F Schinazi, Eisuke Murakami, Aravind Basavapathruni, Junxing Shi, Suzana M Zorca, Chung K Chu, Karen S Anderson | Probing the mechanistic consequences ... | RT,Associated condition,All properties |
| 2003 | William A Beard, Samuel H Wilson | Structural insights into the origins ... | |
| 2003 | Bruno Marchand, Matthias Götte | Site-specific footprinting reveals di... | |
| 2003 | Stefania Paolucci, Fausto Baldanti, Marco Tinelli, Giovanni Maga, Giuseppe Gerna | Detection of a new HIV-1 reverse tran... | |
| 2003 | Jan Balzarini, Erik De Clercq, Beata Kaminska, Andrzej Orzeszko | Synthesis and antiviral activity of s... | |
| 2003 | Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini | Inhibition of human immunodeficiency ... | |
| 2003 | Giuseppina Blanca, Fausto Baldanti, Stefania Paolucci, Alexander Yu Skoblov, Lyubov Victorova, Ulrich HĂĽbscher, Giuseppe Gerna, Silvio Spadari, Giovanni Maga | Nevirapine resistance mutation at cod... | |
| 2003 | Cathryn A Shaw-Reid, Vandna Munshi, Pia Graham, Abigail Wolfe, Marc Witmer, Renee Danzeisen, David B Olsen, Steven S Carroll, Mark Embrey, John S Wai, Michael D Miller, James L Cole, Daria J Hazuda | Inhibition of HIV-1 ribonuclease H by... | |
| 2003 | Evguenia S Svarovskaia, Sara R Cheslock, Wen-Hui Zhang, Wei-Shau Hu, Vinay K Pathak | Retroviral mutation rates and reverse... | |
| 2003 | Marie L Coté, Mark Pflomm, Millie M Georgiadis | Staying straight with A-tracts: a DNA... | |
| 2003 | Romas Geleziunas, Karen Gallagher, Hangchun Zhang, Lee Bacheler, Sena Garber, Jing-Tao Wu, Guoen Shi, Michael J Otto, Raymond F Schinazi, Susan Erickson-Viitanen | HIV-1 resistance profile of the novel... | |
| 2003 | Klaus Klumpp, Julie Qi Hang, Surendran Rajendran, Yanli Yang, Andre Derosier, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin | Two-metal ion mechanism of RNA cleava... | |
| 2003 | Michael A. Parniak, Kyung-Lyum Min, Scott R Budihas, Stuart F J Le Grice, John A Beutler | A fluorescence-based high-throughput ... | |
| 2003 | Boulbaba Selmi, Jerome Deval, Karine Alvarez, Joelle Boretto, Simon Sarfati, Catherine Guerreiro, Bruno Canard | The Y181C substitution in 3'-azido-3'... | |
| 2003 | Mélanie Girouard, Karidia Diallo, Bruno Marchand, Suzanne McCormick, Matthias Götte | Mutations E44D and V118I in the rever... | |
| 2003 | Karidia Diallo, Bluma G Brenner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Matthias Götte, Mark A. Wainberg | The M184V substitution in human immun... | |
| 2003 | Angelo Ranise, Andrea Spallarossa, Silvia Schenone, Olga Bruno, Francesco Bondavalli, Laura Vargiu, Tiziana Marceddu, Massimo Mura, Paolo La Colla, Alessandra Pani | Design, synthesis, SAR, and molecular... | |
| 2003 | Susan E Lim, Mikhail V Ponamarev, Matthew J Longley, William C Copeland | Structural determinants in human DNA ... | |
| 2003 | Tokumi Maruyama, Shigetada Kozai, Tetsuo Yamasaki, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoeck, Graciella Andrei, Erik De Clercq | Synthesis and antiviral activity of 1... | |
| 2003 | MarĂa-Cruz Bonache, Cristina Chamorro, Esther LobatĂłn, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, MarĂa-JosĂ© Camarasa, Ana San-FĂ©lix | Structure-activity relationship studi... | |
| 2003 | Karidia Diallo, Bruno Marchand, Xin Wei, Luciano Cellai, Matthias Götte, Mark A. Wainberg | Diminished RNA primer usage associate... | |
| 2003 | Jaroslaw Poznanski, Maria Bretner, Tadeusz Kulikowski, Jan Balzarini, Arthur Van Aerschot, Erik De Clercq | Synthesis, solution conformation and ... | |
| 2003 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Mutation of amino acids in the connec... | |
| 2003 | Myriam Witvrouw, Christophe Pannecouque, Valery Fikkert, Anke Hantson, Barbara Van Remoortel, Marjan Hezareh, Erik De Clercq, Stephen J Brown | Potent and selective inhibition of HI... | |
| 2003 | Nicolas Sluis-Cremer, Ellis Kempner, Michael A. Parniak | Structure-activity relationships in H... | |
| 2003 | Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Mutations in the 5' end of the human ... | |
| 2003 | Yongseok Choi, Clifford George, Maria J Comin, Joseph J Barchi, Hak Sung Kim, Kenneth A Jacobson, Jan Balzarini, Hiroyuki Mitsuya, Paul L Boyer, Stephen H Hughes, Victor E Marquez | A conformationally locked analogue of... | |
| 2003 | Marie-Pierre Golinelli, Stephen H Hughes | Secondary structure in the nucleic ac... | |
| 2003 | Peter R Meyer, Johan Lennerstrand, Suzanne E Matsuura, Brendan A Larder, Walter A Scott | Effects of dipeptide insertions betwe... | |
| 2003 | Wei Huang, Andrea Gamarnik, Kay Limoli, Christos J Petropoulos, Jeannette M Whitcomb | Amino acid substitutions at position ... | |
| 2003 | Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg | Negative effect of the M184V mutation... | |
| 2003 | Sanjay U C Sankatsing, Gerrit J Weverling, Monika Peeters, Gerben van't Klooster, Boris Gruzdev, Aza Rakhmanova, Sven A Danner, Suzanne Jurriaans, Jan M Prins, Joep M A Lange | TMC125 exerts similar initial antivir... | |
| 2003 | Ge Meng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse transcrip... | |
| 2003 | Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini | Novel human immunodeficiency virus (H... | |
| 2003 | Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, Jingshan Ren, David I Stuart, David K Stammers | Cloning, expression, purification, an... | |
| 2003 | Adrian S Ray, Eisuke Murakami, Aravind Basavapathruni, Joseph A Vaccaro, Dagny Ulrich, Chung K Chu, Raymond F Schinazi, Karen S Anderson | Probing the molecular mechanisms of A... | |
| 2003 | Koyo Ariyoshi, Masakazu Matsuda, Hideka Miura, Sachiko Tateishi, Kaneo Yamada, Wataru Sugiura | Patterns of point mutations associate... | |
| 2003 | Maria Letizia Barreca, Alba Chimirri, Erik De Clercq, Laura De Luca, Anna-Maria Monforte, Pietro Monforte, Angela Rao, Maria ZappalĂ | Anti-HIV agents: design and discovery... | |
| 2003 | Marilyn B Kroeger Smith, Sandra Ruby, Stanislav Horouzhenko, Bryan Buckingham, Julia Richardson, Ina Puleri, Emily Potts, William L Jorgensen, Edward Arnold, Weiming Zhang, Stephen H Hughes, Christopher J Michejda, Richard H Smith | HIV-1 reverse transcriptase variants:... | |
| 2003 | Irene M Lagoja, Christophe Pannecouque, Arthur Van Aerschot, Myriam Witvrouw, Zeger Debyser, Jan Balzarini, Piet Herdewijn, Erik De Clercq | N-aminoimidazole derivatives inhibiti... | |
| 2003 | Eisuke Murakami, Joy Y Feng, Harold R Lee, Jeremiah Hanes, Kenneth A Johnson, Karen S Anderson | Characterization of novel reverse tra... | |
| 2003 | Qian Zhao, Hong Lu, Dominique Schols, Erik De Clercq, Shibo Jiang | Development of a cell-based enzyme-li... | |
| 2003 | Giuseppina Blanca, Igor V Shevelev, Kristijan Ramadan, Giuseppe Villani, Silvio Spadari, Ulrich HĂĽbscher, Giovanni Maga | Human DNA polymerase lambda diverged ... | |
| 2002 | Stefan G Sarafianos, Arthur D Clark, Kalyan Das, Steve Tuske, Jens J Birktoft, Palanichamy Ilankumaran, Andagar R Ramesha, Jane M Sayer, Donald M Jerina, Paul L Boyer, Stephen H Hughes, Edward Arnold | Structures of HIV-1 reverse transcrip... | |
| 2002 | Adrian S Ray, Aravind Basavapathruni, Karen S Anderson | Mechanistic studies to understand the... | |
| 2002 | Patrick K O'Neil, Guoli Sun, Hong Yu, Yacov Ron, Joseph P Dougherty, Bradley D Preston | Mutational analysis of HIV-1 long ter... | |
| 2002 | Karen S Anderson | Perspectives on the molecular mechani... | RT,Associated condition,All properties |
| 2002 | Louis M Mansky | HIV mutagenesis and the evolution of ... | |
| 2002 | Christopher J Hollowood, Steven V Ley, Shigeo Yamanoi | Synthesis of taurospongin A: a potent... | |
| 2002 | Peter R Meyer, Suzanne E Matsuura, Adviye A Tolun, Ingrid Pfeifer, Antero G So, John W Mellors, Walter A Scott | Effects of specific zidovudine resist... | |
| 2002 | Jason W Rausch, Daniela Lener, Jennifer T Miller, John G Julias, Stephen H Hughes, Stuart F J Le Grice | Altering the RNase H primer grip of h... | |
| 2002 | Mickael Rigourd, Chantal Ehresmann, Michael A. Parniak, Bernard Ehresmann, Roland Marquet | Primer unblocking and rescue of DNA s... | |
| 2002 | Robert L Lobato, Eun-Young Kim, Ronald M Kagan, Thomas C Merigan | Genotypic and phenotypic analysis of ... | |
| 2002 | Brigitte Montes, Michel Segondy | Prevalence of the mutational pattern ... | |
| 2002 | Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg | The M184V mutation in HIV-1 reverse t... | |
| 2002 | Yoshiyuki Mizushina, Chikako Murakami, Keisuke Ohta, Hirosato Takikawa, Kenji Mori, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi | Selective inhibition of the activitie... | |
| 2002 | Janice D Pata, Bradford R King, Thomas A Steitz | Assembly, purification and crystalliz... | |
| 2002 | Nobuyuki Kasai, Yoshiyuki Mizushina, Fumio Sugawara, Kengo Sakaguchi | Three-dimensional structural model an... | |
| 2002 | Adrienne M Woodside, F Peter Guengerich | Misincorporation and stalling at O(6)... | |
| 2002 | Fabienne Brulé, Roland Marquet, Liwei Rong, Mark A. Wainberg, Bernard P Roques, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann | Structural and functional properties ... | |
| 2002 | Erik De Clercq | New developments in anti-HIV chemothe... | |
| 2002 | Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak | Destabilization of the HIV-1 reverse ... | |
| 2002 | Yven Van Herrewege, Lieve Penne, Chris Vereecken, Katrien Fransen, Guido van der Groen, Luc Kestens, Jan Balzarini, Guido Vanham | Activity of reverse transcriptase inh... | |
| 2002 | Esther LobatĂłn, Fátima RodrĂguez-Barrios, Federico Gago, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Erik De Clercq, Jan Balzarini, MarĂa-JosĂ© Camarasa, Sonsoles Velázquez | Synthesis of 3' '-substituted TSAO de... | |
| 2002 | Joeri Auwerx, Thomas W North, Bradley D Preston, George J Klarmann, Erik De Clercq, Jan Balzarini | Chimeric human immunodeficiency virus... | |
| 2002 | Bluma G Brenner, Dan Turner, Mark A. Wainberg | HIV-1 drug resistance: can we overcome? | |
| 2002 | Dimitrios Motakis, Michael A. Parniak | A tight-binding mode of inhibition is... | |
| 2002 | Stefano Aquaro, Raffaele Caliò, Jan Balzarini, Maria Concetta Bellocchi, Enrico Garaci, CF Perno | Macrophages and HIV infection: therap... | |
| 2002 | Zeger Debyser, Peter Cherepanov, Bénédicte Van Maele, Erik De Clercq, Myriam Witvrouw | In search of authentic inhibitors of ... | |
| 2002 | Erik De Clercq | New anti-HIV agents and targets. | |
| 2002 | Wim Pluymers, Godwin Pais, Bénédicte Van Maele, Christophe Pannecouque, Valery Fikkert, Terrence R Burke, Erik De Clercq, Myriam Witvrouw, Nouri Neamati, Zeger Debyser | Inhibition of human immunodeficiency ... | |
| 2002 | Joke Snoeck, Sonia Van Dooren, Kristel Van Laethem, Inge Derdelinckx, Eric Van Wijngaerden, Erik De Clercq, Anne-Mieke Vandamme | Prevalence and origin of HIV-1 group ... | |
| 2002 | Qingli Shi, Kamalendra Singh, Aashish Srivastava, Neerja Kaushik, Mukund J Modak | Lysine 152 of MuLV reverse transcript... | |
| 2002 | Christophe Pannecouque, Wim Pluymers, Bénédicte Van Maele, Victor Tetz, Peter Cherepanov, Erik De Clercq, Myriam Witvrouw, Zeger Debyser | New class of HIV integrase inhibitors... | |
| 2002 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | The M184V mutation reduces the select... | |
| 2002 | Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg | Co-receptor usage and HIV-1 intra-cla... | |
| 2002 | L Menéndez-Arias | Molecular basis of fidelity of DNA sy... | |
| 2002 | Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg | Polymorphisms of cytotoxic T-lymphocy... | |
| 2002 | Michael Strerath, Janina Cramer, Tobias Restle, Andreas Marx | Implications of active site constrain... | |
| 2002 | Timothy S Fisher, Vinayaka R Prasad | Substitutions of Phe61 located in the... | RT,Associated condition,All properties |
| 2002 | Marie-Pierre Golinelli, Stephen H Hughes | Nontemplated nucleotide addition by H... | |
| 2002 | Marie-Pierre Golinelli, Stephen H Hughes | Nontemplated base addition by HIV-1 R... | |
| 2002 | Antonio Mas, Blanca M Vázquez-Alvarez, Esteban Domingo, L Menéndez-Arias | Multidrug-resistant HIV-1 reverse tra... | |
| 2002 | Kirsten L White, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Michael D Miller, Lisa K Naeger | Molecular mechanisms of resistance to... | |
| 2002 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Mutations in the RNase H domain of HI... | |
| 2002 | A Geoffrey Skillman, Karl W Maurer, Diana C Roe, Margaret J Stauber, Dolan Eargle, Todd J A Ewing, Angelika Muscate, Elisabeth Davioud-Charvet, Maxine V Medaglia, Robert J Fisher, Edward Arnold, Hong Qiang Gao, Robert W Buckheit, Paul L Boyer, Stephen H Hughes, Irwin D Kuntz, George L Kenyon | A novel mechanism for inhibition of H... | |
| 2002 | Jingshan Ren, Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, David I Stuart, David K Stammers | Structure of HIV-2 reverse transcript... | |
| 2002 | R Masciari, L Cosco, M C Diaco, Dora N Della, T Ferraro, T Raimondi, B Ruperti, E Santandrea | HIV-1: a case of RT67 deletion in a m... | |
| 2002 | Dominique Arion, Nicolas Sluis-Cremer, Kyung-Lyum Min, Michael E Abram, Ronald S Fletcher, Michael A. Parniak | Mutational analysis of Tyr-501 of HIV... | |
| 2002 | Adrienne M Woodside, F Peter Guengerich | Effect of the O6 substituent on misin... | |
| 2002 | Laurent Andréoletti, Laurence Weiss, Ali Si-Mohamed, Christophe Piketty, Thierry Prazuck, Gérard Calamy, Jean-Elie Malkin, Mathieu Matta, François-Xavier Mbopi-Kéou, François Clavel, Michel D Kazatchkine, Laurent Bélec | Multidrug-resistant HIV-1 RNA and pro... | |
| 2002 | Koen K A Van Rompay, Tim B Matthews, Joanne Higgins, Don R Canfield, Ross P Tarara, Mark A. Wainberg, Raymond F Schinazi, Niels C Pedersen, Thomas W North | Virulence and reduced fitness of simi... | |
| 2002 | P Richard Harrigan, Mahboob Salim, David K Stammers, Brian Wynhoven, Zabrina L Brumme, Paula McKenna, Brendan A Larder, S D Kemp | A mutation in the 3' region of the hu... | |
| 2002 | Jimmy Lindberg, Snaevar Sigurdsson, Seved Löwgren, Hans O Andersson, Christer Sahlberg, Rolf Noréen, Kerstin Fridborg, Haijiang Zhang, Torsten Unge | Structural basis for the inhibitory e... | |
| 2002 | Marinela Perpelescu, Jun'ichi Kobayashi, Miho Furuta, Yasutomo Ito, Shunji Izuta, Masaharu Takemura, Motoshi Suzuki, Shonen Yoshida | Novel phenalenone derivatives from a ... | |
| 2002 | N McLellan, Xin Wei, Bruno Marchand, Mark A. Wainberg, Matthias Götte | Nonradioactive detection of retrovira... | |
| 2002 | Giuseppe Campiani, Anna Ramunno, Giovanni Maga, Vito Nacci, Caterina Fattorusso, Bruno Catalanotti, Elena Morelli, Ettore Novellino | Non-nucleoside HIV-1 reverse transcri... | |
| 2002 | Erik De Clercq | Highlights in the development of new ... | |
| 2002 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Nucleoside analog resistance caused b... | |
| 2002 | Lisa K Naeger, Nicolas A Margot, Michael D Miller | ATP-dependent removal of nucleoside r... | |
| 2002 | Phillip P Chamberlain, Jingshan Ren, Charles E Nichols, L Douglas, Johan Lennerstrand, Brendan A Larder, David I Stuart, David K Stammers | Crystal structures of Zidovudine- or ... | |
| 2002 | Giovanni Maga, Silvio Spadari | Combinations against combinations: as... | |
| 2002 | Janina Cramer, Michael Strerath, Andreas Marx, Tobias Restle | Exploring the effects of active site ... | RT,Associated condition,All properties |
| 2001 | Erik De Clercq, Dominique Schols | Inhibition of HIV infection by CXCR4 ... | |
| 2001 | Johan Lennerstrand, Kurt Hertogs, David K Stammers, Brendan A Larder | Correlation between viral resistance ... | |
| 2001 | Stefan G Sarafianos, Kalyan Das, C Tantillo, Arthur D Clark, Jianping Ding, J M Whitcomb, Paul L Boyer, Stephen H Hughes, Edward Arnold | Crystal structure of HIV-1 reverse tr... | |
| 2001 | K E Squires | An introduction to nucleoside and nuc... | |
| 2001 | Lisa K Naeger, Michael D Miller | Mechanisms of HIV-1 nucleoside revers... | |
| 2001 | Jennifer T Miller, Bernard Ehresmann, Ulrich HĂĽbscher, Stuart F J Le Grice | A novel interaction of tRNA(Lys,3) wi... | |
| 2001 | M D Driscoll, Marie-Pierre Golinelli, Stephen H Hughes | In vitro analysis of human immunodefi... | |
| 2001 | J Y Wang, Hong Ling, Wei Wen Yang, R Craigie | Structure of a two-domain fragment of... | |
| 2001 | J L Hammond, D L Koontz, Holly Z Bazmi, J R Beadle, S E Hostetler, G D Kini, Kathy A Aldern, Douglas D Richman, Karl Y Hostetler, John W Mellors | Alkylglycerol prodrugs of phosphonofo... | |
| 2001 | L Menéndez-Arias, A Abraha, ME Quiñones-Mateu, Antonio Mas, M J Camarasa, E J Arts | Functional characterization of chimer... | |
| 2001 | Paul L Boyer, Hong Qiang Gao, Patrick K Clark, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | YADD mutants of human immunodeficienc... | |
| 2001 | Donald W Ludovici, B L De Corte, Michael J Kukla, Hong Ye, Chih Y Ho, Mark A Lichtenstein, Robert W Kavash, Koen Andries, Marie-Pierre P De BĂ©thune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Kalyan Das, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | M Gutiérrez-Rivas, L Menéndez-Arias | A mutation in the primer grip region ... | |
| 2001 | Jingshan Ren, C Nichols, L Bird, P Chamberlain, Kurt L Weaver, S Short, David I Stuart, David K Stammers | Structural mechanisms of drug resista... | |
| 2001 | Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | RNase H cleavage of the 5' end of the... | |
| 2001 | Alba Chimirri, Pietro Monforte, Angela Rao, Maria ZappalĂ , Anna-Maria Monforte, G De Sarro, Christophe Pannecouque, Myriam Witvrouw, Jan Balzarini, Erik De Clercq | Synthesis, biological activity, pharm... | |
| 2001 | Ei-Ichi Kodama, Satoru Kohgo, Kenji Kitano, H Machida, Hiroyuki Gatanaga, S Shigeta, Masao Matsuoka, Hiroshi Ohrui, Hiroyuki Mitsuya | 4'-Ethynyl nucleoside analogs: potent... | |
| 2001 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Selective excision of AZTMP by drug-r... | |
| 2001 | Giovanni Maga, Anna Ramunno, Vito Nacci, Giada A Locatelli, Silvio Spadari, Isabella Fiorini, Fausto Baldanti, Stefania Paolucci, Maurizio Zavattoni, Alberto Bergamini, Bruno Galletti, S Muck, Ulrich Hubscher, Gianluca Giorgi, G Guiso, S Caccia, Giuseppe Campiani | The stereoselective targeting of a sp... | |
| 2001 | G H Kijak, S E Pampuro, M M Avila, C Zala, P Cahn, Mark A. Wainberg, H SalomĂłn | Resistance profiles to antiretroviral... | |
| 2001 | M Madrid, J A Lukin, J D Madura, Jianping Ding, Edward Arnold | Molecular dynamics of HIV-1 reverse t... | |
| 2001 | A L Zakharenko, Dmitry M Kolpashchikov, Svetlana N Khodyreva, Olga I Lavrik, L Menéndez-Arias | Investigation of the dNTP-binding sit... | |
| 2001 | J E Fitzgibbon, B DiCola, Edward Arnold, Kalyan Das, B E Sha, J C Pottage, R Nahass, S Gaur, J F John | HIV-1 reverse transcriptase mutations... | |
| 2001 | M Lavigne, L Polomack, H Buc | Structures of complexes formed by HIV... | |
| 2001 | Erik De Clercq | New developments in anti-HIV chemothe... | |
| 2001 | Hiroshi Ohrui, Hiroyuki Mitsuya | 4'-C-substituted-2'-deoxynucleosides:... | |
| 2001 | Joseph H Chan, J S Hong, R N Hunter , G F Orr, Jill R Cowan, D B Sherman, S M Sparks, B E Reitter, C Webster Andrews, Richard J Hazen, M St Clair, Lawrence R Boone, Robert G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, R J Ott, Jingshan Ren, A Hopkins, David I Stuart, David K Stammers | 2-Amino-6-arylsulfonylbenzonitriles a... | |
| 2001 | Jan Balzarini, MarĂa-JosĂ© Camarasa, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Ana San-FĂ©lix, Sonsoles Velázquez, CF Perno, Erik De Clercq, J N Anderson, Anna Karlsson | Exploitation of the low fidelity of h... | |
| 2001 | Paul L Boyer, Hong Qiang Gao, P Frank, Patrick K Clark, Stephen H Hughes | The basic loop of the RNase H domain ... | |
| 2001 | Z Sevilya, S Loya, Stephen H Hughes, A Hizi | The ribonuclease H activity of the re... | |
| 2001 | G Tachedjian, M Orlova, Stefan G Sarafianos, Edward Arnold, S P Goff | Nonnucleoside reverse transcriptase i... | |
| 2001 | Donald W Ludovici, Michael J Kukla, P G Grous, S Krishnan, Koen Andries, Marie-Pierre P De BĂ©thune, Hilde Azijn, Rudi Pauwels, Erik De Clercq, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | I A Drachkova, Irina O Petruseva, I V Safronov, A L Zakharenko, G V Shishkin, Olga I Lavrik, Svetlana N Khodyreva | [Reagents for modification of protein... | |
| 2001 | Li Fan, Laurie S Kaguni | Multiple regions of subunit interacti... | |
| 2001 | V Molteni, J Greenwald, D Rhodes, Y Hwang, W Kwiatkowski, F D Bushman, J S Siegel, S Choe | Identification of a small-molecule bi... | |
| 2001 | Stephen H Hughes | Molecular matchmaking: NNRTIs can enh... | |
| 2001 | Cristina Chamorro, Esther LobatĂłn, MarĂa-Cruz Bonache, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, Ana San-FĂ©lix, MarĂa-JosĂ© Camarasa | Identification of a novel family of n... | |
| 2001 | Masanori Kameoka, Liwei Rong, Matthias Götte, Chen Liang, Rodney S Russell, Mark A. Wainberg | Role for human immunodeficiency virus... | |
| 2001 | Taurai Tasara, Giovanni Maga, Michael O Hottiger, Ulrich HĂĽbscher | HIV-1 reverse transcriptase and integ... | |
| 2001 | H Pelemans, Robert Esnouf, K L Min, M Parniak, Erik De Clercq, Jan Balzarini | Mutations at amino acid positions 63,... | |
| 2001 | R Hobi, Ulrich HĂĽbscher, K Neftel, E Alteri, B Poncioni, M R Walker, K Woods-Cook, P Schneider, J K Lazdins | Anti-HIV-1 activity in vitro of cefta... | |
| 2001 | A Martinez, C Gil, A Castro, C Perez, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq | Anti-HIV-1 activity of benzothiadiazi... | |
| 2001 | Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Paul L Boyer, Paul Lewi, Paul A J Janssen, Jörg-Peter Kleim, M Rösner, Stephen H Hughes, Edward Arnold | The Lys103Asn mutation of HIV-1 RT: a... | |
| 2001 | Elena N Peletskaya, Paul L Boyer, Alex A Kogon, Patrick K Clark, Heiko Kroth, Jane M Sayer, Donald M Jerina, Stephen H Hughes | Cross-linking of the fingers subdomai... | |
| 2001 | Matthias Götte, Masanori Kameoka, N McLellan, Luciano Cellai, Mark A. Wainberg | Analysis of efficiency and fidelity o... | |
| 2001 | H Pelemans, A Aertsen, Kristel Van Laethem, A-M Vandamme, Erik De Clercq, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Ana San-FĂ©lix, Sonsoles Velázquez, MarĂa-JosĂ© Camarasa, Jan Balzarini | Site-directed mutagenesis of human im... | |
| 2001 | Fátima RodrĂguez-Barrios, C PĂ©rez, Esther LobatĂłn, Sonsoles Velázquez, Cristina Chamorro, Ana San-FĂ©lix, MarĂa-JesĂşs PĂ©rez-PĂ©rez, MarĂa-JosĂ© Camarasa, H Pelemans, Jan Balzarini, Federico Gago | Identification of a putative binding ... | |
| 2001 | Phillip A Furman, J Jeffrey, L L Kiefer, Joy Y Feng, Karen S Anderson, K Borroto-Esoda, E Hill, William C Copeland, Chung K Chu, J P Sommadossi, I Liberman, Raymond F Schinazi, George R Painter | Mechanism of action of 1-beta-D-2,6-d... | |
| 2001 | Catherine Isel, Chantal Ehresmann, P Walter, Bernard Ehresmann, Roland Marquet | The emergence of different resistance... | |
| 2001 | Jan Balzarini, Erik De Clercq | Rapid alternation of drug therapy is ... | |
| 2001 | Liwei Rong, Chen Liang, M Hsu, Xiaofeng Guo, Bernard P Roques, Mark A. Wainberg | HIV-1 nucleocapsid protein and the se... | |
| 2001 | Wim Pluymers, Erik De Clercq, Zeger Debyser | HIV-1 integration as a target for ant... | |
| 2001 | Donald W Ludovici, Robert W Kavash, Michael J Kukla, Chih Y Ho, Hong Ye, B L De Corte, Koen Andries, Marie-Pierre P De BĂ©thune, Hilde Azijn, Rudi Pauwels, H E Moereels, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Paul J Lewi, Kalyan Das, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | Giuseppe Campiani, F Aiello, M Fabbrini, Elena Morelli, Anna Ramunno, S Armaroli, Vito Nacci, A Garofalo, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, L Ventura, B Bongiovanni, M Capozzi, F Bolacchi, Stefano Marini, Massimo Coletta, G Guiso, S Caccia | Quinoxalinylethylpyridylthioureas (QX... | |
| 2000 | Hong Qiang Gao, Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | The role of steric hindrance in 3TC r... | |
| 2000 | P Richard Harrigan, C Stone, P Griffin, I Nájera, Stuart Bloor, S Kemp, M Tisdale, Brendan A Larder | Resistance profile of the human immun... | |
| 2000 | Erik De Clercq | Current lead natural products for the... | |
| 2000 | Jingshan Ren, C Nichols, Louise E Bird, Tsuyoshi Fujiwara, H Sugimoto, David I Stuart, David K Stammers | Binding of the second generation non-... | |
| 2000 | A J Brown, H M Precious, Jeannette M Whitcomb, J K Wong, M Quigg, Wei Huang, E S Daar, R T D'Aquila, P H Keiser, E Connick, Nicholas S Hellmann, Christos J Petropoulos, Douglas D Richman, S J Little | Reduced susceptibility of human immun... | |
| 2000 | A Khorchid, H Javanbakht, S Wise, R Halwani, Michael A. Parniak, Mark A. Wainberg, Lawrence Kleiman | Sequences within Pr160gag-pol affecti... | |
| 2000 | Lawrence A Loeb, J I Mullins | Lethal mutagenesis of HIV by mutageni... | |
| 2000 | K Van Vaerenbergh, Kristel Van Laethem, J Albert, Charles A B Boucher, B Clotet, M Floridia, J Gerstoft, B Hejdeman, C Nielsen, Christophe Pannecouque, L Perrin, M F Pirillo, L Ruiz, J C Schmit, F Schneider, A Schoolmeester, Rob Schuurman, H J Stellbrink, L Stuyver, J Van Lunzen, Barbara Van Remoortel, Eric Van Wijngaerden, S Vella, Myriam Witvrouw, Sabine Yerly, Erik De Clercq, J Destmyer, Anne-Mieke Vandamme | Prevalence and characteristics of mul... | |
| 2000 | Jingshan Ren, John Milton, Kurt L Weaver, Steven A Short, David I Stuart, David K Stammers | Structural basis for the resilience o... | |
| 2000 | H Jonckheere, J Anné, Erik De Clercq | The HIV-1 reverse transcription (RT) ... | |
| 2000 | H Jonckheere, Erik De Clercq, J Anné | Fidelity analysis of HIV-1 reverse tr... | |
| 2000 | A Casimiro-Garcia, Erik De Clercq, Christophe Pannecouque, Myriam Witvrouw, T L Stup, J A Turpin, Robert W Buckheit, Mark Cushman | Synthesis and anti-HIV activity of co... | |
| 2000 | Myriam Witvrouw, Christophe Pannecouque, J Desmyter, Erik De Clercq, Koen Andries | In vitro evaluation of the effect of ... | |
| 2000 | E P Coakley, J M Gillis, S M Hammer | Phenotypic and genotypic resistance p... | |
| 2000 | W R Davis, J Tomsho, S Nikam, E M Cook, D Somand, J A Peliska | Inhibition of HIV-1 reverse transcrip... | |
| 2000 | V Miller, M Ait-Khaled, C Stone, P Griffin, D Mesogiti, A Cutrell, R Harrigan, Schlomo Staszewski, C Katlama, G Pearce, M Tisdale | HIV-1 reverse transcriptase (RT) geno... | |
| 2000 | Matthias Götte, Mark A. Wainberg | Biochemical mechanisms involved in ov... | |
| 2000 | Kamalendra Singh, Neerja Kaushik, J Jin, M Madhusudanan, Mukund J Modak | Role of Q190 of MuLV RT in ddNTP resi... | |
| 2000 | Holly Z Bazmi, J L Hammond, S C Cavalcanti, Chung K Chu, Raymond F Schinazi, John W Mellors | In vitro selection of mutations in th... | |
| 2000 | Giuseppe Campiani, M Fabbrini, Elena Morelli, Vito Nacci, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, C Fracasso, S Caccia | Non-nucleoside HIV-1 reverse transcri... | |
| 2000 | Mickael Rigourd, J M Lanchy, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann, Roland Marquet | Inhibition of the initiation of HIV-1... | |
| 2000 | L T Bacheler, E D Anton, P Kudish, D Baker, J Bunville, K Krakowski, L Bolling, M Aujay, X V Wang, D Ellis, M F Becker, A L Lasut, H J George, D R Spalding, G Hollis, K Abremski | Human immunodeficiency virus type 1 m... | |
| 2000 | Nicolas Sluis-Cremer, G I Dmitrienko, Jan Balzarini, MarĂa-JosĂ© Camarasa, Michael A. Parniak | Human immunodeficiency virus type 1 r... | |
| 2000 | A-M Vandamme, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Kristel Van Laethem, J C Schmit, J Desmyter, Erik De Clercq | Evaluating Clinical Isolates for Thei... | |
| 2000 | Jingshan Ren, J Diprose, J Warren, R M Esnouf, Louise E Bird, Shinji Ikemizu, M Slater, John Milton, Jan Balzarini, David I Stuart, David K Stammers | Phenylethylthiazolylthiourea (PETT) n... | |
| 2000 | Michael A. Parniak, Nicolas Sluis-Cremer | Inhibitors of HIV-1 reverse transcrip... | |
| 2000 | K Nozawa, Motoshi Suzuki, Masaharu Takemura, Shonen Yoshida | In vitro expansion of mammalian telom... | |
| 2000 | Matthias Götte, Dominique Arion, Michael A. Parniak, Mark A. Wainberg | The M184V mutation in the reverse tra... | |
| 2000 | Peter R Meyer, Suzanne E Matsuura, Raymond F Schinazi, Antero G So, Walter A Scott | Differential removal of thymidine nuc... | |
| 2000 | T V Rao, M T Haber, Jane M Sayer, Donald M Jerina | Incorporation of 4-thiothymidine into... | |
| 2000 | G J Latham, E Forgacs, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd | Vertical-scanning mutagenesis of a cr... | |
| 2000 | H Salomon, Mark A. Wainberg, Bluma G Brenner, Yudong Quan, D Rouleau, P Coté, R LeBlanc, E Lefebvre, Bonnie Spira, C Tsoukas, Rafick-Pierre Sekaly, Brian Conway, D Mayers, Jean-Pierre Routy | Prevalence of HIV-1 resistant to anti... | |
| 2000 | Jan Balzarini | Evaluation of Compounds Against Recom... | |
| 2000 | D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando | Drug resistance and drug combination ... | |
| 2000 | F S Shah, Kenneth A Curr, Monica E Hamburgh, M Parniak, Hiroyuki Mitsuya, J G Arnez, Vinayaka R Prasad | Differential influence of nucleoside ... | |
| 2000 | C E Cases-Gonzalez, M Gutierrez-Rivas, L Menéndez-Arias | Coupling ribose selection to fidelity... | |
| 2000 | Nicolas Sluis-Cremer, Dominique Arion, Neerja Kaushik, H Lim, Michael A. Parniak | Mutational analysis of Lys65 of HIV-1... | |
| 2000 | T Imamichi, T Sinha, H Imamichi, Y M Zhang, J A Metcalf, J Falloon, H C Lane | High-level resistance to 3'-azido-3'-... | |
| 2000 | C de Mendoza, V Soriano, C Briones, O Gallego, P Barreiro, A Alvarez, J González-Lahoz | Emergence of zidovudine resistance in... | |
| 2000 | Myriam Witvrouw, Valery Fikkert, Wim Pluymers, B Matthews, K Mardel, Dominique Schols, J Raff, Zeger Debyser, Erik De Clercq, G Holan, Christophe Pannecouque | Polyanionic (i.e., polysulfonate) den... | |
| 2000 | P Bonfanti, I Faggion, S La Seta Catamancio, M Violin, C Balotta, S Rusconi | Response to antiretroviral therapy in... | |
| 2000 | S Najmudin, Marie L Coté, D Sun, S Yohannan, Sherwin P Montano, J Gu, Millie M Georgiadis | Crystal structures of an N-terminal f... | |
| 2000 | Kristel Van Laethem, J C Schmit, H Pelemans, Jan Balzarini, Myriam Witvrouw, MarĂa-JesĂşs PĂ©rez-PĂ©rez, MarĂa-JosĂ© Camarasa, R M Esnouf, Stefano Aquaro, A Cenci, CF Perno, P Hermans, S Sprecher, L Ruiz, B Clotet, Eric Van Wijngaerden, M Van Ranst, J Desmyter, Erik De Clercq, A-M Vandamme | Presence of 2',5'-Bis-O-(tert-butyldi... | |
| 2000 | Ming Yu, W Kabat, Jian Wang | [Rapid detection of drug resistant HI... | |
| 2000 | Christos J Petropoulos, N T Parkin, K L Limoli, Y S Lie, Terri Wrin, Wei Huang, H Tian, D Smith, G A Winslow, D J Capon, Jeannette M Whitcomb | A novel phenotypic drug susceptibilit... | |
| 2000 | Antonio Mas, M Parera, C Briones, V Soriano, Miguel Angel MartĂnez, Esteban Domingo, L MenĂ©ndez-Arias | Role of a dipeptide insertion between... | |
| 2000 | Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak | Molecular mechanisms of HIV-1 resista... | |
| 2000 | K K Weiss, S J Isaacs, N H Tran, Elinor T Adman, Baek Kim | Molecular architecture of the mutagen... | |
| 2000 | H Pelemans, Robert Esnouf, Erik De Clercq, Jan Balzarini | Mutational analysis of trp-229 of hum... | |
| 2000 | Jan Balzarini, Erik De Clercq, A Carbonez, V Burt, Jörg-Peter Kleim | Long-term exposure of HIV type 1-infe... | |
| 2000 | Neerja Kaushik, K Chowdhury, V N Pandey, Mukund J Modak | Valine of the YVDD motif of moloney m... | |
| 2000 | Kurt Hertogs, Stuart Bloor, V De Vroey, C van Den Eynde, Pascale Dehertogh, A van Cauwenberge, Martin StĂĽrmer, T Alcorn, S Wegner, M van Houtte, V Miller, Brendan A Larder | A novel human immunodeficiency virus ... | |
| 2000 | N Richard, H Salomon, Maureen Oliveira, R Rando, T Mansour, Z Gu, Mark A. Wainberg | Selection of resistance-conferring mu... | |
| 2000 | N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of hum... | |
| 2000 | Bluma G Brenner, Mark A. Wainberg, H Salomon, D Rouleau, A Dascal, Bonnie Spira, Rafick-Pierre Sekaly, Brian Conway, Jean-Pierre Routy | Resistance to antiretroviral drugs in... | |
| 2000 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Analysis of mutations at positions 11... | |
| 2000 | L Mu, Stefan G Sarafianos, Marc C Nicklaus, P Russ, Maqbool A Siddiqui, H Ford, Hiroyuki Mitsuya, R Le, Eiichi N Kodama, Chris Meier, T Knispel, L Anderson, Joseph J Barchi, Victor E Marquez | Interactions of conformationally bias... | |
| 2000 | Neerja Kaushik, T T Talele, P K Pandey, D Harris, P N Yadav, V N Pandey | Role of glutamine 151 of human immuno... | |
| 2000 | Dominique Arion, Nicolas Sluis-Cremer, Michael A. Parniak | Mechanism by which phosphonoformic ac... | |
| 2000 | Paul L Boyer, Stephen H Hughes | Effects of amino acid substitutions a... | |
| 1999 | M Wisniewski, C Palaniappan, Z Fu, Stuart F J Le Grice, P Fay, Robert A Bambara | Mutations in the primer grip region o... | |
| 1999 | J M de Muys, H Gourdeau, N Nguyen-Ba, D L Taylor, P S Ahmed, T Mansour, C Locas, N Richard, Mark A. Wainberg, R F Rando | Anti-human immunodeficiency virus typ... | |
| 1999 | D A Lewis, Katarzyna Bebenek, William A Beard, Samuel H Wilson, Thomas A Kunkel | Uniquely altered DNA replication fide... | |
| 1999 | Dominique Arion, Michael A. Parniak | HIV resistance to zidovudine: the rol... | |
| 1999 | Matthias Götte, G Maier, A M Onori, Luciano Cellai, Mark A. Wainberg, H Heumann | Temporal coordination between initiat... | |
| 1999 | Lawrence A Loeb, J M Essigmann, F Kazazi, Jun Zhang, K D Rose, J I Mullins | Lethal mutagenesis of HIV with mutage... | |
| 1999 | Paul L Boyer, J Lisziewicz, F Lori, Stephen H Hughes | Analysis of amino insertion mutations... | |
| 1999 | L L Furge, F Peter Guengerich | Explanation of pre-steady-state kinet... | |
| 1999 | Matthias Götte, Xincang Li, Mark A. Wainberg | HIV-1 reverse transcription: a brief ... | |
| 1999 | Joy Y Feng, Karen S Anderson | Mechanistic studies comparing the inc... | |
| 1999 | Jan Balzarini | Suppression of resistance to drugs ta... | |
| 1999 | M E Arranz, J A DĂaz, S T Ingate, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, S Vega | Synthesis and anti-HIV activity of 1,... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Touching the heart of HIV-1 drug resi... | |
| 1999 | J J de Jong, J Goudsmit, V V Lukashov, M E Hillebrand, E Baan, R Huismans, Sven A Danner, J H ten Veen, F de Wolf, Suzanne Jurriaans | Insertion of two amino acids combined... | |
| 1999 | N Richar, Yudong Quan, H Salomon, M Hsu, J Bedard, P Richard Harrigan, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of HIV... | |
| 1999 | Myriam Witvrouw, Christophe Pannecouque, Kristel Van Laethem, J Desmyter, Erik De Clercq, Anne-Mieke Vandamme | Activity of non-nucleoside reverse tr... | |
| 1999 | Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Similarities and differences in the R... | |
| 1999 | M Madrid, A Jacobo-Molina, Jianping Ding, Edward Arnold | Major subdomain rearrangement in HIV-... | |
| 1999 | T Szyperski, Matthias Götte, M Billeter, E Perola, Luciano Cellai, H Heumann, K Wüthrich | NMR structure of the chimeric hybrid ... | |
| 1999 | Alexandra Vaisman, Susan E Lim, S M Patrick, William C Copeland, David C Hinkle, J J Turchi, Stephen G Chaney | Effect of DNA polymerases and high mo... | |
| 1999 | J Izopet, A Bicart-See, C Pasquier, K Sandres, E Bonnet, B Marchou, J Puel, P Massip | Mutations conferring resistance to zi... | |
| 1999 | G Borkow, Dominique Arion, Mark A. Wainberg, Michael A. Parniak | The thiocarboxanilide nonnucleoside i... | |
| 1999 | Sylvie Doublié, M R Sawaya, Tom Ellenberger | An open and closed case for all polym... | |
| 1999 | Mark A. Wainberg, Michael D Miller, Yudong Quan, H Salomon, A S Mulato, P D Lamy, Nicolas A Margot, K E Anton, J M Cherrington | In vitro selection and characterizati... | |
| 1999 | Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari | Molecular basis for the enantioselect... | |
| 1999 | Y Goldgur, R Craigie, G H Cohen, Tsuyoshi Fujiwara, T Yoshinaga, T Fujishita, H Sugimoto, T Endo, H Murai, D R Davies | Structure of the HIV-1 integrase cata... | |
| 1999 | S Cen, Yangxin Huang, A Khorchid, J L Darlix, Mark A. Wainberg, Lawrence Kleiman | The role of Pr55(gag) in the annealin... | |
| 1999 | Brendan A Larder, Stuart Bloor, S D Kemp, Kurt Hertogs, R L Desmet, V Miller, M Sturmer, Schlomo Staszewski, Jingshan Ren, David K Stammers, David I Stuart, Rudi Pauwels | A family of insertion mutations betwe... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Arthur D Clark, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Lamivudine (3TC) resistance in HIV-1 ... | |
| 1999 | Katarzyna Bebenek, J C Boyer, Thomas A Kunkel | The base substitution fidelity of HIV... | |
| 1999 | Yudong Quan, Liwei Rong, Chen Liang, Mark A. Wainberg | Reverse transcriptase inhibitors can ... | |
| 1999 | Michael D Miller, K E Anton, A S Mulato, P D Lamy, J M Cherrington | Human immunodeficiency virus type 1 e... | |
| 1999 | H RĂĽbsamen-Waigmann, E Huguenel, A Shah, A Paessens, H J Ruoff, H von Briesen, A Immelmann, U Dietrich, Mark A. Wainberg | Resistance mutations selected in vivo... | |
| 1999 | M D Powell, William A Beard, Katarzyna Bebenek, K J Howard, Stuart F J Le Grice, Thomas A Darden, Thomas A Kunkel, Samuel H Wilson, J G Levin | Residues in the alphaH and alphaI hel... | |
| 1999 | M Högberg, Christer Sahlberg, P Engelhardt, Rolf Noréen, J Kangasmetsä, N G Johansson, Bo Oberg, L Vrang, Haijiang Zhang, B L Sahlberg, Torsten Unge, S Lövgren, Kerstin Fridborg, K Bäckbro | Urea-PETT compounds as a new class of... | |
| 1999 | Baek Kim, J C Ayran, S G Sagar, Elinor T Adman, S M Fuller, N H Tran, J Horrigan | New human immunodeficiency virus, typ... | |
| 1999 | Junxing Shi, J J McAtee, S Schlueter Wirtz, P Tharnish, A Juodawlkis, Dennis C Liotta, Raymond F Schinazi | Synthesis and biological evaluation o... | |
| 1999 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, David I Stuart, David K Stammers | Crystallographic analysis of the bind... | |
| 1999 | Myriam Witvrouw, Christophe Pannecouque, Erik De Clercq, E Fernández-Alvarez, J L Marco | Inhibition of human immunodeficiency ... | |
| 1999 | Neerja Kaushik, Kamalendra Singh, I Alluru, Mukund J Modak | Tyrosine 222, a member of the YXDD mo... | |
| 1999 | Sonsoles Velázquez, V Tuñón, M L Jimeno, Cristina Chamorro, Erik De Clercq, Jan Balzarini, MarĂa-JosĂ© Camarasa | Potential multifunctional inhibitors ... | |
| 1999 | I Pellegrin, J Izopet, J Reynes, M Denayrolles, Brigitte Montes, J L Pellegrin, P Massip, J Puel, H Fleury, Michel Segondy | Emergence of zidovudine and multidrug... | |
| 1999 | H Idriss, S Kawa, Z Damuni, E B Thompson, Samuel H Wilson | HIV-1 reverse transcriptase is phosph... | |
| 1999 | Andrew L Hopkins, Jingshan Ren, Hiromichi Tanaka, Masanori Baba, M Okamato, David I Stuart, David K Stammers | Design of MKC-442 (emivirine) analogu... | |
| 1999 | Zucai Suo, S J Lippard, Kenneth A Johnson | Single d(GpG)/cis-diammineplatinum(II... | |
| 1999 | Taurai Tasara, Mario Amacker, Ulrich HĂĽbscher | Intramolecular chimeras of the p51 su... | |
| 1999 | P F Lin, C J González, B Griffith, G Friedland, V Calvez, F Ferchal, Raymond F Schinazi, D H Shepp, A B Ashraf, Mark A. Wainberg, V Soriano, John W Mellors, R J Colonno | Stavudine resistance: an update on su... | |
| 1999 | A Rakik, M Ait-Khaled, P Griffin, T A Thomas, M Tisdale, Jörg-Peter Kleim | A novel genotype encoding a single am... | |
| 1999 | Thomas A Steitz | DNA polymerases: structural diversity... | |
| 1999 | Giuseppe Campiani, Elena Morelli, M Fabbrini, Vito Nacci, Giovanni Greco, Ettore Novellino, Anna Ramunno, Giovanni Maga, Silvio Spadari, G Caliendo, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, A Nacca, S Caccia | Pyrrolobenzoxazepinone derivatives as... | |
| 1999 | Yudong Quan, Dimitrios Motakis, R Buckheit, Z Q Xu, M T Flavin, Michael A. Parniak, Mark A. Wainberg | Sensitivity and resistance to (+)-cal... | |
| 1999 | Z Gu, Mark A. Wainberg, N Nguyen-Ba, L L'Heureux, J M de Muys, T L Bowlin, R F Rando | Mechanism of action and in vitro acti... | |
| 1999 | Peter R Meyer, Suzanne E Matsuura, A M Mian, Antero G So, Walter A Scott | A mechanism of AZT resistance: an inc... | |
| 1999 | Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | Action of a new mammalian DNA polymer... | |
| 1999 | Andreas Marx, M Spichty, Mario Amacker, U Schwitter, Ulrich HĂĽbscher, Thomas A Bickle, Giovanni Maga, Bernd Giese | Probing interactions between HIV-1 re... | |
| 1998 | F J Palella, K M Delaney, A C Moorman, M O Loveless, J Fuhrer, G A Satten, D J Aschman, S D Holmberg | Declining morbidity and mortality amo... | |
| 1998 | Hong Qiang Gao, Paul L Boyer, Edward Arnold, Stephen H Hughes | Effects of mutations in the polymeras... | |
| 1998 | H Pelemans, R M Esnouf, Michael A. Parniak, A-M Vandamme, Erik De Clercq, Jan Balzarini | A proline-to-histidine substitution a... | |
| 1998 | Tsuyoshi Fujiwara, Akira Sato, M el-Farrash, S Miki, K Abe, Y Isaka, M Kodama, Y Wu, L B Chen, H Harada, H Sugimoto, Masami Hatanaka, Y Hinuma | S-1153 inhibits replication of known ... | |
| 1998 | L M Demeter, P M Meehan, G Morse, M A Fischl, M Para, W Powderly, J Leedom, J Holden-Wiltse, C Greisberger, K Wood, J Timpone, L K Wathen, T Nevin, L Resnick, D H Batts, R C Reichman | Phase I study of atevirdine mesylate ... | |
| 1998 | Yudong Quan, P Inouye, Chen Liang, Liwei Rong, Matthias Götte, Mark A. Wainberg | Dominance of the E89G substitution in... | |
| 1998 | Hao Huang, R Chopra, G L Verdine, S C Harrison | Structure of a covalently trapped cat... | |
| 1998 | Michael D Miller, P D Lamy, M D Fuller, A S Mulato, Nicolas A Margot, T Cihlar, J M Cherrington | Human immunodeficiency virus type 1 r... | |
| 1998 | Peter R Meyer, Suzanne E Matsuura, Antero G So, Walter A Scott | Unblocking of chain-terminated primer... | |
| 1998 | I Choudhury, Jianhong Wang, A B Rabson, S Stein, S Pooyan, S Stein, M J Leibowitz | Inhibition of HIV-1 replication by a ... | |
| 1998 | Baek Kim, T R Hathaway, Lawrence A Loeb | Fidelity of mutant HIV-1 reverse tran... | |
| 1998 | Mario Amacker, Ulrich HĂĽbscher | Chimeric HIV-1 and feline immunodefic... | |
| 1998 | M von Janta-Lipinski, B Costisella, H Ochs, Ulrich HĂĽbscher, P Hafkemeyer, E Matthes | Newly synthesized L-enantiomers of 3'... | |
| 1998 | C Katlama, M A Valantin, S Matheron, A Coutellier, V Calvez, D Descamps, C Longuet, M Bonmarchand, R Tubiana, M De Sa, R Lancar, Henri Agut, F Brun-Vezinet, D Costagliola | Efficacy and tolerability of stavudin... | |
| 1998 | M Wasner, Dominique Arion, G Borkow, A Noronha, A H Uddin, Michael A. Parniak, Masad J Damha | Physicochemical and biochemical prope... | |
| 1998 | Zucai Suo, Kenneth A Johnson | DNA secondary structure effects on DN... | |
| 1998 | Zucai Suo, Kenneth A Johnson | Selective inhibition of HIV-1 reverse... | |
| 1998 | H Salomon, Julio S G Montaner, A Belmonte, Mark A. Wainberg | Diminished HIV-1 sensitivity to stavu... | |
| 1998 | Mark Cushman, A Casimiro-Garcia, E Hejchman, J A Ruell, M Huang, C A Schaeffer, K Williamson, W G Rice, Robert W Buckheit | New alkenyldiarylmethanes with enhanc... | |
| 1998 | P Inouye, E Cherry, M Hsu, S Zolla-Pazner, Mark A. Wainberg | Neutralizing antibodies directed agai... | |
| 1998 | Yudong Quan, Z Gu, Xincang Li, Chen Liang, Michael A. Parniak, Mark A. Wainberg | Endogenous reverse transcriptase assa... | |
| 1998 | H Kwon, N Pelletier, C DeLuca, P Genin, S Cisternas, R Lin, Mark A. Wainberg, J Hiscott | Inducible expression of IkappaBalpha ... | |
| 1998 | S W Graves, Allison A Johnson, Kenneth A Johnson | Expression, purification, and initial... | Processivity,Kd,Vmax,All properties |
| 1998 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, J Warren, Jan Balzarini, David I Stuart, David K Stammers | Crystal structures of HIV-1 reverse t... | |
| 1998 | Akitsu Ogawa, Takashi Murate, Shunji Izuta, Masaharu Takemura, Kyoji Furuta, Jun'ichi Kobayashi, T Kamikawa, Y Nimura, Shonen Yoshida | Sulfated glycoglycerolipid from archa... | |
| 1998 | Y Hsiou, Kalyan Das, Jianping Ding, Arthur D Clark, Jörg-Peter Kleim, M Rösner, I Winkler, G Riess, Stephen H Hughes, Edward Arnold | Structures of Tyr188Leu mutant and wi... | |
| 1998 | Andreas Marx, Mario Amacker, M Stucki, Ulrich HĂĽbscher, Thomas A Bickle, Bernd Giese | 4'-Acylated thymidine 5'-triphosphate... | |
| 1998 | D Harris, P N Yadav, V N Pandey | Loss of polymerase activity due to Ty... | |
| 1998 | Matthias Götte, G Maier, H J Gross, H Heumann | Localization of the active site of HI... | |
| 1998 | D V Nissley, Paul L Boyer, D J Garfinkel, Stephen H Hughes, J N Strathern | Hybrid Ty1/HIV-1 elements used to det... | |
| 1998 | G Tachedjian, John W Mellors, H Bazmi, J Mills | Impaired fitness of foscarnet-resista... | |
| 1998 | Paul L Boyer, Hong Qiang Gao, Stephen H Hughes | A mutation at position 190 of human i... | |
| 1998 | Sonsoles Velázquez, Cristina Chamorro, MarĂa-JesĂşs PĂ©rez-PĂ©rez, R Alvarez, M L Jimeno, A MartĂn-Domenech, C PĂ©rez, Federico Gago, Erik De Clercq, Jan Balzarini, Ana San-FĂ©lix, MarĂa-JosĂ© Camarasa | Abasic analogues of TSAO-T as the fir... | |
| 1998 | H Togashi, Yoshiyuki Mizushina, Masaharu Takemura, Fumio Sugawara, Hiroyuki Koshino, Y Esumi, J Uzawa, H Kumagai, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | 4-Hydroxy-17-methylincisterol, an inh... | |
| 1998 | A Acel, B E Udashkin, Mark A. Wainberg, E A Faust | Efficient gap repair catalyzed in vit... | |
| 1998 | Joseph A Vaccaro, Karen S Anderson | Implication of the tRNA initiation st... | |
| 1998 | Monica E Hamburgh, William C Drosopoulos, Vinayaka R Prasad | The influence of 3TC-resistance mutat... | |
| 1998 | D Harris, Neerja Kaushik, P K Pandey, P N Yadav, V N Pandey | Functional analysis of amino acid res... | |
| 1998 | C Tamalet, J Izopet, N Koch, J Fantini, N Yahi | Stable rearrangements of the beta3-be... | |
| 1998 | Myriam Witvrouw, M E Arranz, Christophe Pannecouque, R Declercq, H Jonckheere, J C Schmit, A-M Vandamme, J A Diaz, S T Ingate, J Desmyter, Robert Esnouf, L Van Meervelt, S Vega, Jan Balzarini, Erik De Clercq | 1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,... | |
| 1998 | Yudong Quan, Chen Liang, P Inouye, Mark A. Wainberg | Enhanced impairment of chain elongati... | |
| 1998 | Kamalendra Singh, Mukund J Modak | A unified DNA- and dNTP-binding mode ... | |
| 1998 | E Cherry, Chen Liang, Liwei Rong, Yudong Quan, P Inouye, Xincang Li, N Morin, M Kotler, Mark A. Wainberg | Characterization of human immunodefic... | |
| 1998 | Bruno Canard, S R Sarfati, Charles C Richardson | Enhanced binding of azidothymidine-re... | |
| 1998 | Erik De Clercq | New perspectives for the treatment of... | |
| 1998 | J C Schmit, L Ruiz, L Stuyver, Kristel Van Laethem, I Vanderlinden, T Puig, R Rossau, J Desmyter, Erik De Clercq, B Clotet, A-M Vandamme | Comparison of the LiPA HIV-1 RT test,... | |
| 1998 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, E Yvonne Jones, I Kirby, J Keeling, C K Ross, Brendan A Larder, David I Stuart, David K Stammers | 3'-Azido-3'-deoxythymidine drug resis... | |
| 1998 | Dominique Arion, Neerja Kaushik, Suzanne McCormick, G Borkow, Michael A. Parniak | Phenotypic mechanism of HIV-1 resista... | |
| 1998 | E Cherry, N Morin, Mark A. Wainberg | Effect of HIV constructs containing p... | |
| 1998 | M A Winters, K L Coolley, Y A Girard, D J Levee, H Hamdan, R W Shafer, D A Katzenstein, T C Merigan | A 6-basepair insert in the reverse tr... | |
| 1998 | H J Einolf, N Schnetz-Boutaud, F Peter Guengerich | Steady-state and pre-steady-state kin... | |
| 1998 | M Nakayabu, S Miwa, Motoshi Suzuki, Shunji Izuta, G Sobue, Shonen Yoshida | Mismatched nucleotides may facilitate... | |
| 1998 | Silvio Spadari, Giovanni Maga, A Verri, Federico Focher | Molecular basis for the antiviral and... | |
| 1998 | Yoshiyuki Mizushina, L Hanashima, Tsuyoshi Yamaguchi, Masaharu Takemura, Fumio Sugawara, Mineo Saneyoshi, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | A mushroom fruiting body-inducing sub... | |
| 1998 | Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | Sulfoquinovosyldiacylglycerol, KM043,... | |
| 1998 | William A Beard, Katarzyna Bebenek, Thomas A Darden, Lin Li, Rajendra Prasad, Thomas A Kunkel, Samuel H Wilson | Vertical-scanning mutagenesis of a cr... | |
| 1998 | William C Drosopoulos, Lisa F Rezende, Mark A. Wainberg, Vinayaka R Prasad | Virtues of being faithful: can we lim... | |
| 1998 | Cristina Chamorro, MarĂa-JosĂ© Camarasa, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Erik De Clercq, Jan Balzarini, Ana San FĂ©lix | An approach towards the synthesis of ... | |
| 1998 | H Jonckheere, Myriam Witvrouw, Erik De Clercq, J Anné | Lamivudine resistance of HIV type 1 d... | |
| 1998 | Erik De Clercq | The role of non-nucleoside reverse tr... | |
| 1998 | Joachim Jaeger, Tobias Restle, Thomas A Steitz | The structure of HIV-1 reverse transc... | |
| 1998 | Jianping Ding, Kalyan Das, Y Hsiou, Stefan G Sarafianos, Arthur D Clark, A Jacobo-Molina, C Tantillo, Stephen H Hughes, Edward Arnold | Structure and functional implications... | |
| 1997 | R M Esnouf, Jingshan Ren, Andrew L Hopkins, C K Ross, E Yvonne Jones, David K Stammers, David I Stuart | Unique features in the structure of t... | |
| 1997 | L L Furge, F Peter Guengerich | Analysis of nucleotide insertion and ... | |
| 1997 | E Forgacs, G Latham, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd | Probing structure/function relationsh... | |
| 1997 | M D Powell, M Ghosh, P S Jacques, K J Howard, Stuart F J Le Grice, J G Levin | Alanine-scanning mutations in the "pr... | |
| 1997 | Myriam Witvrouw, Jan Balzarini, Christophe Pannecouque, S Jhaumeer-Laulloo, J A Esté, Dominique Schols, Peter Cherepanov, J C Schmit, Zeger Debyser, A-M Vandamme, J Desmyter, S R Ramadas, Erik De Clercq | SRR-SB3, a disulfide-containing macro... | |
| 1997 | Jan Balzarini, H Pelemans, G Riess, M Roesner, I Winkler, Erik De Clercq, Jörg-Peter Kleim | Zidovudine-resistant human immunodefi... | |
| 1997 | Jan Balzarini, Erik De Clercq, K Uberla | SIV/HIV-1 hybrid virus expressing the... | |
| 1997 | G Borkow, Ronald S Fletcher, J Barnard, Dominique Arion, Dimitrios Motakis, G I Dmitrienko, Michael A. Parniak | Inhibition of the ribonuclease H and ... | |
| 1997 | J Mak, A Khorchid, Q Cao, Yangxin Huang, I Lowy, Michael A. Parniak, Vinayaka R Prasad, Mark A. Wainberg, Lawrence Kleiman | Effects of mutations in Pr160gag-pol ... | |
| 1997 | G Gao, M Orlova, Millie M Georgiadis, W A Hendrickson, S P Goff | Conferring RNA polymerase activity to... | |
| 1997 | M Hsu, P Inouye, L Rezende, N Richard, Zhongjie Li, Vinayaka R Prasad, Mark A. Wainberg | Higher fidelity of RNA-dependent DNA ... | |
| 1997 | Jörg-Peter Kleim, I Winkler, M Rösner, R Kirsch, H Rübsamen-Waigmann, A Paessens, G Riess | In vitro selection for different muta... | |
| 1997 | Mark A. Wainberg | Increased fidelity of drug-selected M... | |
| 1997 | Zucai Suo, Kenneth A Johnson | Effect of RNA secondary structure on ... | |
| 1997 | Y M Lin, H Anderson, M T Flavin, Y H Pai, E Mata-Greenwood, T Pengsuparp, J M Pezzuto, Raymond F Schinazi, Stephen H Hughes, F C Chen | In vitro anti-HIV activity of biflavo... | |
| 1997 | G Borkow, J Barnard, T M Nguyen, A Belmonte, Mark A. Wainberg, Michael A. Parniak | Chemical barriers to human immunodefi... | |
| 1997 | C Palaniappan, M Wisniewski, P S Jacques, Stuart F J Le Grice, P J Fay, Robert A Bambara | Mutations within the primer grip regi... | |
| 1997 | Zucai Suo, Kenneth A Johnson | RNA secondary structure switching dur... | |
| 1997 | Chen Liang, Liwei Rong, N Morin, E Cherry, Yangxin Huang, Lawrence Kleiman, Mark A. Wainberg | The roles of the human immunodeficien... | |
| 1997 | Erik De Clercq | Development of resistance of human im... | |
| 1997 | R Krebs, U Immendörfer, S H Thrall, B M Wöhrl, R S Goody | Single-step kinetics of HIV-1 reverse... | |
| 1997 | W Tong, C D Lu, S K Sharma, S Matsuura, Antero G So, Walter A Scott | Nucleotide-induced stable complex for... | |
| 1997 | Takayuki Ueno, Hiroyuki Mitsuya | Comparative enzymatic study of HIV-1 ... | |
| 1997 | Thomas Roth, Marshall L Morningstar, Paul L Boyer, Stephen H Hughes, Robert W Buckheit, Christopher J Michejda | Synthesis and biological activity of ... | |
| 1997 | Mario Amacker, M Hottiger, R Mossi, Ulrich HĂĽbscher | HIV-1 nucleocapsid protein and replic... | |
| 1997 | M Tisdale, T Alnadaf, D Cousens | Combination of mutations in human imm... | |
| 1997 | Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, Koen Andries, Robert W Buckheit, Richard H Smith | Molecular modeling of HIV-1 reverse t... | |
| 1997 | Yoshiyuki Mizushina, Shonen Yoshida, Akio Matsukage, Kengo Sakaguchi | The inhibitory action of fatty acids ... | |
| 1997 | Ashwini S Kamath-Loeb, A Hizi, Hironori Kasai, Lawrence A Loeb | Incorporation of the guanosine tripho... | |
| 1997 | T Rubinek, M Bakhanashvili, R Taube, O Avidan, A Hizi | The fidelity of 3' misinsertion and m... | |
| 1997 | M A Winters, R W Shafer, R A Jellinger, G Mamtora, T Gingeras, T C Merigan | Human immunodeficiency virus type 1 r... | |
| 1997 | Jianping Ding, Stephen H Hughes, Edward Arnold | Protein-nucleic acid interactions and... | |
| 1997 | H Hara, T Fujihashi, T Sakata, A Kaji, H Kaji | Tetrahydronaphthalene lignan compound... | |
| 1997 | Erik De Clercq | In search of a selective antiviral ch... | |
| 1997 | I V Safronov, N V Shcherbik, Svetlana N Khodyreva, V A Vlasov, M I Dobrikov, G V Shishkin, Olga I Lavrik | [New photoreactive N(4)-substituted d... | |
| 1997 | S G Kerr, Karen S Anderson | Pre-steady-state kinetic characteriza... | |
| 1997 | Stefano Aquaro, CF Perno, Emanuela Balestra, Jan Balzarini, A Cenci, M Francesconi, S Panti, F Serra, N Villani, Raffaele Caliò | Inhibition of replication of HIV in p... | |
| 1997 | S Loya, Hong Qiang Gao, O Avidan, Paul L Boyer, Stephen H Hughes, A Hizi | Subunit-specific mutagenesis of the c... | |
| 1997 | R M Esnouf, David I Stuart, Erik De Clercq, E Schwartz, Jan Balzarini | Models which explain the inhibition o... | |
| 1997 | Giovanni Maga, Mario Amacker, N Ruel, Ulrich HĂĽbscher, Silvio Spadari | Resistance to nevirapine of HIV-1 rev... | |
| 1997 | Robert W Buckheit, M J Snow, V Fliakas-Boltz, T L Kinjerski, J D Russell, L A Pallansch, W G Brouwer, S S Yang | Highly potent oxathiin carboxanilide ... | |
| 1997 | Bruno Canard, R Sarfati, Charles C Richardson | Binding of RNA template to a complex ... | |
| 1997 | Chen Liang, Xincang Li, Liwei Rong, P Inouye, Yudong Quan, Lawrence Kleiman, Mark A. Wainberg | The importance of the A-rich loop in ... | |
| 1997 | A Hizi, Ashwini S Kamath-Loeb, K D Rose, Lawrence A Loeb | Mutagenesis by human immunodeficiency... | |
| 1997 | B P Burnett, Charles S McHenry | Posttranscriptional modification of r... | |
| 1997 | Neerja Kaushik, D Harris, N Rege, Mukund J Modak, P N Yadav, V N Pandey | Role of glutamine-151 of human immuno... | |
| 1997 | H Pelemans, Robert Esnouf, A Dunkler, Michael A. Parniak, A-M Vandamme, Anna Karlsson, Erik De Clercq, Jörg-Peter Kleim, Jan Balzarini | Characteristics of the Pro225His muta... | |
| 1997 | W Keulen, N K Back, A van Wijk, Charles A B Boucher, Ben Berkhout | Initial appearance of the 184Ile vari... | |
| 1997 | Myriam Witvrouw, Erik De Clercq | Sulfated polysaccharides extracted fr... | |
| 1997 | J Barnard, G Borkow, Michael A. Parniak | The thiocarboxanilide nonnucleoside U... | |
| 1997 | M Tanaka, R V Srinivas, Takayuki Ueno, M F Kavlick, F K Hui, A Fridland, J S Driscoll, Hiroyuki Mitsuya | In vitro induction of human immunodef... | |
| 1997 | G Borkow, Dominique Arion, A Noronha, M Scartozzi, Masad J Damha, Michael A. Parniak | Inhibitory potency of R-region specif... | |
| 1997 | F Lori, A G Malykh, A Foli, R Maserati, A De Antoni, L Minoli, D Padrini, A Degli Antoni, E Barchi, H Jessen, Mark A. Wainberg, R C Gallo, J Lisziewicz | Combination of a drug targeting the c... | |
| 1997 | A De Antoni, A Foli, J Lisziewicz, F Lori | Mutations in the pol gene of human im... | |
| 1997 | Zucai Suo, Kenneth A Johnson | Effect of RNA secondary structure on ... | |
| 1996 | J Ji, N J Clegg, K R Peterson, A L Jackson, C D Laird, Lawrence A Loeb | In vitro expansion of GGC:GCC repeats... | |
| 1996 | Yangxin Huang, A Shalom, Zhongjie Li, Jiong Wang, J Mak, Mark A. Wainberg, Lawrence Kleiman | Effects of modifying the tRNA(3Lys) a... | |
| 1996 | Jan Balzarini, H Pelemans, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Ana San-FĂ©lix, MarĂa-JosĂ© Camarasa, Erik De Clercq, Anna Karlsson | Marked inhibitory activity of non-nuc... | |
| 1996 | S Ingate, Erik De Clercq, Jan Balzarini, MarĂa-JosĂ© Camarasa | Novel L-lyxo and 5'-deoxy-5'-modified... | |
| 1996 | Dominique Arion, R Harada, Xincang Li, Mark A. Wainberg, Michael A. Parniak | HIV-1 reverse transcriptase shows no ... | |
| 1996 | A Foli, K M Sogocio, B Anderson, M Kavlick, M W Saville, Mark A. Wainberg, Z Gu, J M Cherrington, Hiroyuki Mitsuya, R Yarchoan | In vitro selection and molecular char... | |
| 1996 | D L Winslow, S Garber, C Reid, H Scarnati, D Baker, M M Rayner, E D Anton | Selection conditions affect the evolu... | |
| 1996 | H D Sun, S X Qiu, L Z Lin, Z Y Wang, Z W Lin, T Pengsuparp, J M Pezzuto, H H Fong, G A Cordell, N R Farnsworth | Nigranoic acid, a triterpenoid from S... | |
| 1996 | Baek Kim, T R Hathaway, Lawrence A Loeb | Human immunodeficiency virus reverse ... | |
| 1996 | T Pengsuparp, M Serit, Stephen H Hughes, D D Soejarto, J M Pezzuto | Specific inhibition of human immunode... | |
| 1996 | Jan Balzarini, O Wedgwood, J Kruining, H Pelemans, R Heijtink, Erik De Clercq, Christopher McGuigan | Anti-HIV and anti-HBV activity and re... | |
| 1996 | Olga I Lavrik, Rajendra Prasad, William A Beard, I V Safronov, M I Dobrikov, Deepak K Srivastava, G V Shishkin, T G Wood, Samuel H Wilson | dNTP binding to HIV-1 reverse transcr... | |
| 1996 | Kalyan Das, Jianping Ding, Y Hsiou, Arthur D Clark, H Moereels, Luc Koymans, Koen Andries, Rudi Pauwels, Paul A J Janssen, Paul L Boyer, Patrick K Clark, Richard H Smith, Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Edward Arnold | Crystal structures of 8-Cl and 9-Cl T... | |
| 1996 | Z Gu, Xincang Li, Yudong Quan, Michael A. Parniak, Mark A. Wainberg | Studies of neutralizing monoclonal an... | |
| 1996 | E.J. Arts, J P Marois, Z Gu, Stuart F J Le Grice, Mark A. Wainberg | Effects of 3'-deoxynucleoside 5'-trip... | |
| 1996 | V N Pandey, Neerja Kaushik, N Rege, Stefan G Sarafianos, P N Yadav, Mukund J Modak | Role of methionine 184 of human immun... | |
| 1996 | CF Perno, Emanuela Balestra, Stefano Aquaro, S Panti, A Cenci, G Lazzarino, B Tavazzi, D Di Pierro, Jan Balzarini, R Calio | Potent inhibition of human immunodefi... | |
| 1996 | Xincang Li, Yudong Quan, E.J. Arts, Zhongjie Li, Bradley D Preston, H de Rocquigny, Bernard P Roques, J L Darlix, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg | Human immunodeficiency virus Type 1 n... | |
| 1996 | Neerja Kaushik, N Rege, P N Yadav, Stefan G Sarafianos, Mukund J Modak, V N Pandey | Biochemical analysis of catalytically... | |
| 1996 | G Tachedjian, J Mellors, H Bazmi, C Birch, J Mills | Zidovudine resistance is suppressed b... | |
| 1996 | Charles A B Boucher, W Keulen, T van Bommel, Monique Nijhuis, D de Jong, M D de Jong, P Schipper, N K Back | Human immunodeficiency virus type 1 d... | |
| 1996 | J A Esté, K De Vreese, Myriam Witvrouw, J C Schmit, A-M Vandamme, J Anné, J Desmyter, G W Henson, G Bridger, Erik De Clercq | Antiviral activity of the bicyclam de... | |
| 1996 | F Soler, C Poujade, M Evers, J C Carry, Y HĂ©nin, Anne Bousseau, T Huet, Rudi Pauwels, Erik De Clercq, J F Mayaux, J B Le Pecq, N Dereu | Betulinic acid derivatives: a new cla... | |
| 1996 | Rudi Pauwels, Erik De Clercq | Development of vaginal microbicides f... | |
| 1996 | Zeger Debyser, Erik De Clercq | Chemical crosslinking of the subunits... | |
| 1996 | R A Olmsted, D E Slade, L A Kopta, S M Poppe, T J Poel, S W Newport, K B Rank, C Biles, R A Morge, T J Dueweke, Y Yagi, D L Romero, R C Thomas, S K Sharma, W G Tarpley | (Alkylamino) piperidine bis(heteroary... | |
| 1996 | Jan Balzarini, W G Brouwer, D C Dao, E M Osika, Erik De Clercq | Identification of novel thiocarboxani... | |
| 1996 | M G Davis, J E Wilson, N A VanDraanen, W H Miller, George A Freeman, S M Daluge, F L Boyd, A E Aulabaugh, George R Painter, Lawrence R Boone | DNA polymerase activity of hepatitis ... | |
| 1996 | B M Moore, Ke Li, Michael B Doughty | Deoxyadenosine-based DNA polymerase p... | |
| 1996 | Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Stephen H Hughes, Edward Arnold | Structure of unliganded HIV-1 reverse... | |
| 1996 | L Hong, A Treharne, J A Hartsuck, S Foundling, J Tang | Crystal structures of complexes of a ... | |
| 1996 | Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak | The K65R mutation confers increased D... | RT,Cloned or native,Full length or truncated,Extension from RNA primer,All properties |
| 1996 | Yudong Quan, Z Gu, Xincang Li, Zhongjie Li, C D Morrow, Mark A. Wainberg | Endogenous reverse transcription assa... | |
| 1996 | G Yang, Q Song, M Charles, William C Drosopoulos, Edward Arnold, Vinayaka R Prasad | Use of chimeric human immunodeficienc... | |
| 1996 | R A Spence, Karen S Anderson, Kenneth A Johnson | HIV-1 reverse transcriptase resistanc... | |
| 1996 | Edward Arnold, Kalyan Das, Jianping Ding, P N Yadav, Y Hsiou, Paul L Boyer, Stephen H Hughes | Targeting HIV reverse transcriptase f... | |
| 1996 | J M Cherrington, A S Mulato, M D Fuller, M S Chen | Novel mutation (K70E) in human immuno... | |
| 1996 | D J Hooker, G Tachedjian, A E Solomon, A D Gurusinghe, S Land, C Birch, J L Anderson, B M Roy, Edward Arnold, N J Deacon | An in vivo mutation from leucine to t... | |
| 1996 | P Richard Harrigan, I Kinghorn, Stuart Bloor, S D Kemp, I Nájera, A Kohli, Brendan A Larder | Significance of amino acid variation ... | |
| 1996 | Jörg-Peter Kleim, M Rösner, I Winkler, A Paessens, R Kirsch, Y Hsiou, Edward Arnold, G Riess | Selective pressure of a quinoxaline n... | |
| 1996 | J E Wilson, A Aulabaugh, B Caligan, S McPherson, J K Wakefield, S Jablonski, C D Morrow, J E Reardon, Phillip A Furman | Human immunodeficiency virus type-1 r... | |
| 1996 | William A Beard, Dana T Minnick, C L Wade, Rajendra Prasad, R L Won, A Kumar, Thomas A Kunkel, Samuel H Wilson | Role of the "helix clamp" in HIV-1 re... | |
| 1996 | M Hottiger, Ulrich HĂĽbscher | Human Immunodeficiency Virus type 1 r... | |
| 1996 | Stefan G Sarafianos, U Kortz, M T Pope, Mukund J Modak | Mechanism of polyoxometalate-mediated... | |
| 1996 | William C Drosopoulos, Vinayaka R Prasad | Increased polymerase fidelity of E89G... | |
| 1996 | Ronald S Fletcher, G Holleschak, Eva Nagy, Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak | Single-step purification of recombina... | |
| 1996 | Mark A. Wainberg, William C Drosopoulos, H Salomon, M Hsu, G Borkow, M Parniak, Z Gu, Q Song, J Manne, S Islam, G Castriota, Vinayaka R Prasad | Enhanced fidelity of 3TC-selected mut... | |
| 1996 | M Evers, C Poujade, F Soler, Y Ribeill, C James, Y Lelièvre, J C Gueguen, D Reisdorf, I Morize, Rudi Pauwels, Erik De Clercq, Y Hénin, Anne Bousseau, J F Mayaux, J B Le Pecq, N Dereu | Betulinic acid derivatives: a new cla... | |
| 1996 | Michael J Lutz, H A Held, M Hottiger, Ulrich HĂĽbscher, Steven A Benner | Differential discrimination of DNA po... | |
| 1996 | Mark A. Wainberg, M Hsu, Z Gu, G Borkow, Michael A. Parniak | Effectiveness of 3TC in HIV clinical ... | |
| 1996 | Erik De Clercq | Chemotherapy of human immunodeficienc... | |
| 1996 | A M MartĂn-Hernández, Esteban Domingo, L MenĂ©ndez-Arias | Human immunodeficiency virus type 1 r... | |
| 1996 | H Jonckheere, K De Vreese, Zeger Debyser, J Vandekerckhove, Jan Balzarini, J Desmyter, Erik De Clercq, J Anné | A two plasmid co-expression system in... | |
| 1996 | L M Mansky | Forward mutation rate of human immuno... | |
| 1996 | Mark A. Wainberg, L Lewis, H Salomon, Z Gu, A Keller, Nick Cammack, J Goldsmith, J Church, Bonnie Spira, S Wheeler, P Pizzo | Resistance to (-)-2',3'-dideoxy-3'-th... | |
| 1996 | A K Iversen, R W Shafer, K Wehrly, M A Winters, J I Mullins, B Chesebro, T C Merigan | Multidrug-resistant human immunodefic... | |
| 1996 | Zhongjie Li, A Shalom, Yangxin Huang, J Mak, E Arts, Mark A. Wainberg, Lawrence Kleiman | Multiple forms of tRNA(Lys3) in HIV-1. | |
| 1996 | J M Cherrington, M D Fuller, A S Mulato, S J Allen, S C Kunder, M A Ussery, Z Lesnikowski, Raymond F Schinazi, J P Sommadossi, M S Chen | Comparative kinetic analyses of inter... | |
| 1996 | Dominique Arion, Ronald S Fletcher, G Borkow, MarĂa-JosĂ© Camarasa, Jan Balzarini, G I Dmitrienko, Michael A. Parniak | Differences in the inhibition of huma... | |
| 1996 | D Bellarosa, G Antonelli, F Bambacioni, D Giannotti, G Viti, R Nannicini, A Giachetti, F Dianzani, Myriam Witvrouw, Rudi Pauwels, J Desmyter, Erik De Clercq | New arylpyrido-diazepine and -thiodia... | |
| 1996 | N K Back, Monique Nijhuis, W Keulen, Charles A B Boucher, B O Oude Essink, A B van Kuilenburg, A H van Gennip, Ben Berkhout | Reduced replication of 3TC-resistant ... | |
| 1996 | Andrew L Hopkins, Jingshan Ren, R M Esnouf, B E Willcox, E Yvonne Jones, C Ross, T Miyasaka, R T Walker, Hiromichi Tanaka, David K Stammers, David I Stuart | Complexes of HIV-1 reverse transcript... | |
| 1995 | Robert W Buckheit, V Fliakas-Boltz, S Yeagy-Bargo, O Weislow, D L Mayers, Paul L Boyer, Stephen H Hughes, B C Pan, S H Chu, J P Bader | Resistance to 1-[(2-hydroxyethoxy)met... | |
| 1995 | Takayuki Ueno, T Shirasaka, Hiroyuki Mitsuya | Enzymatic characterization of human i... | |
| 1995 | Jörg-Peter Kleim, R Bender, R Kirsch, C Meichsner, A Paessens, M Rösner, H Rübsamen-Waigmann, R Kaiser, M Wichers, K E Schneweis | Preclinical evaluation of HBY 097, a ... | |
| 1995 | Hongxing Zhang, Yang Zhang, T Spicer, D Henrard, B J Poiesz | Nascent human immunodeficiency virus ... | |
| 1995 | K Rittinger, G Divita, R S Goody | Human immunodeficiency virus reverse ... | |
| 1995 | P N Yadav, J S Yadav, Mukund J Modak | Nucleoside drug resistance in HIV-1 r... | |
| 1995 | Jianping Ding, Kalyan Das, H Moereels, Luc Koymans, Koen Andries, Paul A J Janssen, Stephen H Hughes, Edward Arnold | Structure of HIV-1 RT/TIBO R 86183 co... | |
| 1995 | Baek Kim, Lawrence A Loeb | Human immunodeficiency virus reverse ... | |
| 1995 | R Esnouf, Jingshan Ren, C Ross, Y Jones, D Stammers, David I Stuart | Mechanism of inhibition of HIV-1 reve... | |
| 1995 | R R Vyas, A K Basu | DNA polymerase action on an oligonucl... | |
| 1995 | D W Rodgers, S J Gamblin, B A Harris, S Ray, J S Culp, B Hellmig, D J Woolf, C Debouck, S C Harrison | The structure of unliganded reverse t... | |
| 1995 | Silvio Spadari, Giovanni Maga, A Verri, A Bendiscioli, L Tondelli, M Capobianco, F Colonna, A Garbesi, Federico Focher | Lack of stereospecificity of some cel... | |
| 1995 | P H Patel, A Jacobo-Molina, Jianping Ding, C Tantillo, Art D Clark, R Raag, R G Nanni, Stephen H Hughes, Edward Arnold | Insights into DNA polymerization mech... | |
| 1995 | B M Wöhrl, C Tantillo, Edward Arnold, Stuart F J Le Grice | An expanded model of replicating huma... | |
| 1995 | Edward Arnold, Jianping Ding, Stephen H Hughes, Z Hostomsky | Structures of DNA and RNA polymerases... | |
| 1995 | Jingshan Ren, R Esnouf, A Hopkins, C Ross, Y Jones, D Stammers, David I Stuart | The structure of HIV-1 reverse transc... | |
| 1995 | Marilyn B Kroeger Smith, C A Rouzer, L A Taneyhill, N A Smith, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, H Moereels, Luc Koymans, Edward Arnold | Molecular modeling studies of HIV-1 r... | |
| 1995 | Jan Balzarini, Masanori Baba, Erik De Clercq | Differential activities of 1-[(2-hydr... | |
| 1995 | Jianping Ding, Kalyan Das, C Tantillo, Weiming Zhang, Arthur D Clark, S Jessen, Xiaoqing Lu, Y Hsiou, A Jacobo-Molina, Koen Andries | Structure of HIV-1 reverse transcript... | |
| 1995 | L M Mansky, H M Temin | Lower in vivo mutation rate of human ... | |
| 1995 | Jan Balzarini | Novel concepts in the treatment of hu... | |
| 1995 | Z Gu, Yudong Quan, Zhongjie Li, E.J. Arts, Mark A. Wainberg | Effects of non-nucleoside inhibitors ... | |
| 1995 | Ronald S Fletcher, K Syed, S Mithani, G I Dmitrienko, Michael A. Parniak | Carboxanilide derivative non-nucleosi... | |
| 1995 | Matthias Götte, S Fackler, T Hermann, E Perola, Luciano Cellai, H J Gross, Stuart F J Le Grice, H Heumann | HIV-1 reverse transcriptase-associate... | |
| 1995 | Jingshan Ren, R Esnouf, E Garman, D Somers, C Ross, I Kirby, J Keeling, G Darby, Y Jones, David I Stuart | High resolution structures of HIV-1 R... | |
| 1995 | Mark A. Wainberg, Z Gu | Targeting HIV reverse transcriptase i... | |
| 1995 | Haijiang Zhang, L Vrang, K Bäckbro, P Lind, Christer Sahlberg, Torsten Unge, Bo Oberg | Inhibition of human immunodeficiency ... | |
| 1995 | V McKiel, Z Gu, Mark A. Wainberg, J Hiscott | Inhibition of human immunodeficiency ... | |
| 1995 | M Ghosh, K J Howard, Craig E Cameron, Stephen J Benkovic, Stephen H Hughes, Stuart F J Le Grice | Truncating alpha-helix E' of p66 huma... | |
| 1995 | Robert W Buckheit, T L Kinjerski, V Fliakas-Boltz, J D Russell, T L Stup, L A Pallansch, W G Brouwer, D C Dao, W A Harrison, R J Schultz | Structure-activity and cross-resistan... | |
| 1995 | Sonsoles Velázquez, R Alvarez, Ana San-FĂ©lix, M L Jimeno, Erik De Clercq, Jan Balzarini, MarĂa-JosĂ© Camarasa | Synthesis and anti-HIV activity of [A... | |
| 1995 | Jan Balzarini, M Weeger, MarĂa-JosĂ© Camarasa, Erik De Clercq, K Uberla | Sensitivity/resistance profile of a s... | |
| 1995 | G Tachedjian, D J Hooker, A D Gurusinghe, H Bazmi, N J Deacon, J Mellors, C Birch, J Mills | Characterisation of foscarnet-resista... | |
| 1995 | Erik De Clercq, Jan Balzarini | Knocking out human immunodeficiency v... | |
| 1995 | Katarzyna Bebenek, Thomas A Kunkel | Analyzing fidelity of DNA polymerases. | Frameshift Error Rate,Overall Error Rate,All properties |
| 1995 | Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari | Stereospecificity of human DNA polyme... | |
| 1995 | T Shirasaka, M F Kavlick, Takayuki Ueno, W Y Gao, E Kojima, M L Alcaide, S Chokekijchai, B M Roy, Edward Arnold, R Yarchoan | Emergence of human immunodeficiency v... | |
| 1995 | Jan Balzarini, W G Brouwer, E E Felauer, Erik De Clercq, Anna Karlsson | Activity of various thiocarboxanilide... | |
| 1995 | J Horlacher, M Hottiger, Vladimir N Podust, Ulrich HĂĽbscher, Steven A Benner | Recognition by viral and cellular DNA... | |
| 1995 | M Hottiger, K Gramatikoff, O Georgiev, C Chaponnier, W Schaffner, Ulrich HĂĽbscher | The large subunit of HIV-1 reverse tr... | |
| 1995 | Jan Balzarini, MarĂa-JesĂşs PĂ©rez-PĂ©rez, S VĂ©lazquez, Ana San-FĂ©lix, MarĂa-JosĂ© Camarasa, Erik De Clercq, Anna Karlsson | Suppression of the breakthrough of hu... | |
| 1995 | S D Young, S F Britcher, L O Tran, L S Payne, W C Lumma, T A Lyle, J R Huff, P S Anderson, David B Olsen, Steven S Carroll | L-743, 726 (DMP-266): a novel, highly... | |
| 1995 | John W Mellors, Holly Z Bazmi, Raymond F Schinazi, B M Roy, Y Hsiou, Edward Arnold, J Weir, D L Mayers | Novel mutations in reverse transcript... | |
| 1995 | M I Anazodo, H Salomon, A D Friesen, Mark A. Wainberg, J A Wright | Antiviral activity and protection of ... | |
| 1995 | Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak | Site-directed mutagenesis of arginine... | |
| 1995 | Mark A. Wainberg, Z Gu, H Salomon, E.J. Arts, Lawrence Kleiman, Michael A. Parniak, N Morin | [Molecular basis and clinical signifi... | |
| 1995 | N M Gray, C L Marr, C R Penn, J M Cameron, R C Bethell | The intracellular phosphorylation of ... | |
| 1995 | M I Anazodo, Mark A. Wainberg, A D Friesen, J A Wright | Sequence-specific inhibition of gene ... | |
| 1995 | Ronald S Fletcher, Dominique Arion, G Borkow, Mark A. Wainberg, G I Dmitrienko, Michael A. Parniak | Synergistic inhibition of HIV-1 rever... | |
| 1995 | Rob Schuurman, Monique Nijhuis, R van Leeuwen, P Schipper, D de Jong, P Collis, Sven A Danner, J Mulder, C Loveday, C Christopherson | Rapid changes in human immunodeficien... | |
| 1995 | M Jaju, William A Beard, Samuel H Wilson | Human immunodeficiency virus type 1 r... | |
| 1995 | Baek Kim, Lawrence A Loeb | A screen in Escherichia coli for nucl... | |
| 1995 | E.J. Arts, Zhongjie Li, Mark A. Wainberg | Analysis of Primer Extension and the ... | |
| 1995 | Z Gu, E.J. Arts, Michael A. Parniak, Mark A. Wainberg | Mutated K65R recombinant reverse tran... | |
| 1995 | R J Germinario, T DeSantis, Mark A. Wainberg | Insulin-like growth factor 1 and insu... | |
| 1995 | Brendan A Larder, S D Kemp, P Richard Harrigan | Potential mechanism for sustained ant... | |
| 1995 | R A Spence, W M Kati, Karen S Anderson, Kenneth A Johnson | Mechanism of inhibition of HIV-1 reve... | |
| 1995 | Katarzyna Bebenek, William A Beard, J R Casas-Finet, H R Kim, Thomas A Darden, Samuel H Wilson, Thomas A Kunkel | Reduced frameshift fidelity and proce... | |
| 1995 | Y Törnevik, B Ullman, Jan Balzarini, B Wahren, Staffan Eriksson | Cytotoxicity of 3'-azido-3'-deoxythym... | |
| 1995 | Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak | Glutamine 151 participates in the sub... | |
| 1995 | M Sala, S Wain-Hobson, F Schaeffer | Human immunodeficiency virus type 1 r... | |
| 1994 | Erik De Clercq | How to overcome resistance of HIV-1 t... | |
| 1994 | J Mak, M Jiang, Mark A. Wainberg, M L Hammarskjöld, D Rekosh, Lawrence Kleiman | Role of Pr160gag-pol in mediating the... | |
| 1994 | I Kang, Jing-Houng Wang | Design of structure-based reverse tra... | |
| 1994 | T Rubinek, S Loya, M Shaharabany, Stephen H Hughes, Patrick K Clark, A Hizi | The catalytic properties of the rever... | |
| 1994 | Douglas D Richman, D Havlir, J Corbeil, D Looney, C Ignacio, S A Spector, J Sullivan, S Cheeseman, K Barringer, D Pauletti | Nevirapine resistance mutations of hu... | |
| 1994 | Paul L Boyer, Jianping Ding, Edward Arnold, Stephen H Hughes | Subunit specificity of mutations that... | |
| 1994 | Paul L Boyer, Andrea L Ferris, Patrick K Clark, J Whitmer, P Frank, C Tantillo, Edward Arnold, Stephen H Hughes | Mutational analysis of the fingers an... | |
| 1994 | Z Gu, Ronald S Fletcher, E.J. Arts, Mark A. Wainberg, Michael A. Parniak | The K65R mutant reverse transcriptase... | |
| 1994 | C Tantillo, Jianping Ding, A Jacobo-Molina, R G Nanni, Paul L Boyer, Stephen H Hughes, Rudi Pauwels, Koen Andries, Paul A J Janssen, Edward Arnold | Locations of anti-AIDS drug binding s... | |
| 1994 | S Zinnen, J C Hsieh, P Modrich | Misincorporation and mispaired primer... | |
| 1994 | J Ji, Jean-SĂ©bastien Hoffmann, L Loeb | Mutagenicity and pausing of HIV rever... | |
| 1994 | Myron F Goodman, H Cai, Linda B Bloom, R Eritja | Nucleotide insertion and primer exten... | |
| 1994 | H Jonckheere, J M Taymans, Jan Balzarini, Sonsoles Velázquez, MarĂa-JosĂ© Camarasa, J Desmyter, Erik De Clercq, J AnnĂ© | Resistance of HIV-1 reverse transcrip... | |
| 1994 | T Hermann, T Meier, Matthias Götte, H Heumann | The 'helix clamp' in HIV-1 reverse tr... | |
| 1994 | L Mercure, B J Brenner, D Phaneuf, C Tsoukas, Mark A. Wainberg | Effect of 3'-azido-3'-deoxythymidine ... | |
| 1994 | William A Beard, Samuel H Wilson | Site-directed mutagenesis of HIV reve... | |
| 1994 | M D Delahunty, Samuel H Wilson, R L Karpel | Studies on primer binding of HIV-1 re... | |
| 1994 | S F Lacey, Brendan A Larder | Novel mutation (V75T) in human immuno... | |
| 1994 | P N Yadav, J S Yadav, Edward Arnold, Mukund J Modak | A computer-assisted analysis of conse... | |
| 1994 | V W Byrnes, E A Emini, W A Schleif, J H Condra, C L Schneider, W J Long, J A Wolfgang, D J Graham, L Gotlib, A J Schlabach | Susceptibilities of human immunodefic... | |
| 1994 | A-M Vandamme, Zeger Debyser, Rudi Pauwels, K De Vreese, P Goubau, M Youle, B Gazzard, P A Stoffels, G F Cauwenbergh, J Anne | Characterization of HIV-1 strains iso... | |
| 1994 | G Gosselin, Raymond F Schinazi, J P Sommadossi, C Mathé, M C Bergogne, A M Aubertin, A Kirn, J L Imbach | Anti-human immunodeficiency virus act... | |
| 1994 | A Okruszek, M Olesiak, Jan Balzarini | The synthesis of nucleoside 5'-O-(1,1... | |
| 1994 | Erik De Clercq | HIV resistance to reverse transcripta... | |
| 1994 | H Pelletier, M R Sawaya, A Kumar, Samuel H Wilson, J Kraut | Structures of ternary complexes of ra... | |
| 1994 | Jan Balzarini, Jörg-Peter Kleim, G Riess, MarĂa-JosĂ© Camarasa, Erik De Clercq, Anna Karlsson | Sensitivity of (138 Glu-->Lys) mutate... | |
| 1994 | S V Doronin, M I Dobrikov, M Buckle, P Roux, H Buc, Olga I Lavrik | Affinity modification of human immuno... | |
| 1994 | J Jäger, S J Smerdon, Jianhong Wang, D C Boisvert, Thomas A Steitz | Comparison of three different crystal... | |
| 1994 | E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg | Mature reverse transcriptase (p66/p51... | |
| 1994 | Jan Balzarini, Anna Karlsson, V V Sardana, E A Emini, MarĂa-JosĂ© Camarasa, Erik De Clercq | Human immunodeficiency virus 1 (HIV-1... | |
| 1994 | M Smith, H Salomon, Mark A. Wainberg | Development and significance of nucle... | |
| 1994 | Jianping Ding, A Jacobo-Molina, C Tantillo, Xiaoqing Lu, R G Nanni, Edward Arnold | Buried surface analysis of HIV-1 reve... | |
| 1994 | S Loya, M Bakhanashvili, R Tal, Stephen H Hughes, Paul L Boyer, A Hizi | Enzymatic properties of two mutants o... | |
| 1994 | Torsten Unge, S Knight, R Bhikhabhai, S Lövgren, Z Dauter, K Wilson, B Strandberg | 2.2 A resolution structure of the ami... | |
| 1994 | E.J. Arts, Xincang Li, Z Gu, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg | Comparison of deoxyoligonucleotide an... | |
| 1994 | S J Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, A J Chirino, J M Friedman, P A Rice, Thomas A Steitz | Structure of the binding site for non... | |
| 1994 | P S Jacques, B M Wöhrl, M Ottmann, J L Darlix, Stuart F J Le Grice | Mutating the "primer grip" of p66 HIV... | |
| 1994 | Paul L Boyer, C Tantillo, A Jacobo-Molina, R G Nanni, Jianping Ding, Edward Arnold, Stephen H Hughes | Sensitivity of wild-type human immuno... | |
| 1994 | M H Nguyen, Raymond F Schinazi, C Shi, N M Goudgaon, P M McKenna, John W Mellors | Resistance of human immunodeficiency ... | |
| 1994 | Z Gu, Q Gao, H Fang, Michael A. Parniak, Bluma G Brenner, Mark A. Wainberg | Identification of novel mutations tha... | |
| 1994 | M A Fisher, P N Yadav, J Yadav, D Kristol, Edward Arnold, Mukund J Modak | Identification of a pharmacophore for... | |
| 1994 | Masanori Baba, S Shigeta, S Yuasa, H Takashima, K Sekiya, M Ubasawa, Hiromichi Tanaka, T Miyasaka, R T Walker, Erik De Clercq | Preclinical evaluation of MKC-442, a ... | |
| 1994 | J Ji, Lawrence A Loeb | Fidelity of HIV-1 reverse transcripta... | |
| 1994 | M R Sawaya, H Pelletier, A Kumar, Samuel H Wilson, J Kraut | Crystal structure of rat DNA polymera... | |
| 1994 | Jan Balzarini, Anna Karlsson, C Meichsner, A Paessens, G Riess, Erik De Clercq, Jörg-Peter Kleim | Resistance pattern of human immunodef... | |
| 1994 | E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg | DNA found in human immunodeficiency v... | |
| 1994 | Erik De Clercq | New developments in the chemotherapy ... | |
| 1994 | Rudi Pauwels, Koen Andries, Zeger Debyser, Michael J Kukla, Dominique Schols, H J Breslin, R Woestenborghs, J Desmyter, M A Janssen, Erik De Clercq | New tetrahydroimidazo[4,5,1-jk][1,4]-... | |
| 1994 | M Hottiger, Vladimir N Podust, R L Thimmig, C McHenry, Ulrich HĂĽbscher | Strand displacement activity of the h... | |
| 1993 | Paul L Boyer, M J Currens, James B McMahon, M R Boyd, Stephen H Hughes | Analysis of nonnucleoside drug-resist... | |
| 1993 | S St Luce, E Arts, R Geleziunas, S Bour, Mark A. Wainberg | Infection of human monocyte-derived m... | |
| 1993 | S P Becerra, A Kumar, Samuel H Wilson | Expression of polypeptides of human i... | |
| 1993 | Katarzyna Bebenek, J Abbotts, Samuel H Wilson, Thomas A Kunkel | Error-prone polymerization by HIV-1 r... | |
| 1993 | H Cai, Linda B Bloom, R Eritja, Myron F Goodman | Kinetics of deoxyribonucleotide inser... | |
| 1993 | J Abbotts, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson | Mechanism of HIV-1 reverse transcript... | |
| 1993 | William A Beard, Samuel H Wilson | Kinetic analysis of template.primer i... | |
| 1993 | Robert W Sobol, W L Fisher, N L Reichenbach, A Kumar, William A Beard, Samuel H Wilson, R Charubala, W Pfleiderer, R J Suhadolnik | HIV-1 reverse transcriptase: inhibiti... | |
| 1993 | Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg | The same mutation that encodes low-le... | |
| 1993 | J C Hsieh, S Zinnen, P Modrich | Kinetic mechanism of the DNA-dependen... | |
| 1993 | Svetlana N Khodyreva, Vladimir N Podust, D S Sergeev, E M Ivanova, E I Frolova, A A Koshkin, T S Godovikova, V F Zarytova, Miria Ricchetti, Olga I Lavrik | Comparison of interactions of 5'-deri... | |
| 1993 | Jan Balzarini, Anna Karlsson, Erik De Clercq | Human immunodeficiency virus type 1 d... | |
| 1993 | W Y Gao, A Cara, R C Gallo, F Lori | Low levels of deoxynucleotides in per... | |
| 1993 | G Maass, U Immendoerfer, B Koenig, U Leser, B Mueller, R Goody, E Pfaff | Viral resistance to the thiazolo-iso-... | |
| 1993 | Xincang Li, E Amandoron, Mark A. Wainberg, Michael A. Parniak | Generation and characterization of mu... | |
| 1993 | Mark A. Wainberg, H Salomon, Bonnie Spira, L Mercure, J Wainberg, K Nagai, Z Bentwich, J Montaner | HIV resistance to anti-viral drugs. | |
| 1993 | Jörg-Peter Kleim, R Bender, U M Billhardt, C Meichsner, G Riess, M Rösner, I Winkler, A Paessens | Activity of a novel quinoxaline deriv... | |
| 1993 | M S Saag, E A Emini, O L Laskin, J Douglas, W I Lapidus, W A Schleif, R J Whitley, C Hildebrand, V W Byrnes, John C Kappes | A short-term clinical evaluation of L... | |
| 1993 | T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley | A mutation in reverse transcriptase o... | |
| 1993 | Jan Balzarini, Anna Karlsson, A-M Vandamme, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Haijiang Zhang, L Vrang, Bo Oberg, K Bäckbro, Torsten Unge, Ana San-FĂ©lix | Human immunodeficiency virus type 1 (... | |
| 1993 | Jan Balzarini, Anna Karlsson, MarĂa-JesĂşs PĂ©rez-PĂ©rez, MarĂa-JosĂ© Camarasa, Erik De Clercq | Knocking-out concentrations of HIV-1-... | |
| 1993 | C T Wang, Yongqing Zhang, J McDermott, E Barklis | Conditional infectivity of a human im... | |
| 1993 | Johan Neyts, F Stals, C Bruggeman, Erik De Clercq | Activity of the anti-HIV agent 9-(2-p... | |
| 1993 | Myron F Goodman, S Creighton, Linda B Bloom, John Petruska | Biochemical basis of DNA replication ... | |
| 1993 | Kristin A Eckert, Thomas A Kunkel | Fidelity of DNA synthesis catalyzed b... | Cloned or native,Full length or truncated,Specific Activity,3-5' exo,Nucleotide Substitution Rate,All properties |
| 1993 | A Jacobo-Molina, Jianping Ding, R G Nanni, Arthur D Clark, Xiaoqing Lu, C Tantillo, R L Williams, G Kamer, Andrea L Ferris, Patrick K Clark | Crystal structure of human immunodefi... | |
| 1993 | D Chattopadhyay, B C Finzel, S H Munson, D B Evans, S K Sharma, N A Strakalaitus, D P Brunner, F M Eckenrode, Z Dauter, C Betzel, H M Einspahr | Crystallographic analyses of an activ... | |
| 1993 | R L Thimmig, Charles S McHenry | Human immunodeficiency virus reverse ... | |
| 1993 | John W Mellors, G J Im, Enzo Tramontano, S R Winkler, D J Medina, Ginger E Dutschman, Holly Z Bazmi, G Piras, C J Gonzalez, Yung-Chi Cheng | A single conservative amino acid subs... | |
| 1993 | Thomas A Steitz, S Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, J M Friedman, Lorena S Beese, P A Rice | Two DNA polymerases: HIV reverse tran... | |
| 1993 | S Kawa, A Kumar, J S Smith, S P Becerra, William A Beard, Samuel H Wilson, E B Thompson | Expression and purification of the HI... | |
| 1993 | M Tisdale, S D Kemp, N R Parry, Brendan A Larder | Rapid in vitro selection of human imm... | |
| 1993 | A Kumar, H R Kim, Robert W Sobol, S P Becerra, B J Lee, D L Hatfield, R J Suhadolnik, Samuel H Wilson | Mapping of nucleic acid binding in pr... | |
| 1993 | Erik De Clercq | Antiviral agents: characteristic acti... | |
| 1993 | Zeger Debyser, K De Vreese, P P Knops-Gerrits, V Baekelandt, R Bhikhabhai, B Strandberg, Rudi Pauwels, J Anné, J Desmyter, Erik De Clercq | Kinetics of different human immunodef... | |
| 1993 | Erik De Clercq | HIV-1-specific RT inhibitors: highly ... | |
| 1993 | J L Martin, J E Wilson, R L Haynes, Phillip A Furman | Mechanism of resistance of human immu... | |
| 1993 | Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors | Characterization of human immunodefic... | |
| 1993 | M S Chen, R T Suttmann, E Papp, P D Cannon, M J McRoberts, C Bach, William C Copeland, Teresa S-F Wang | Selective action of 4'-azidothymidine... | |
| 1993 | R Sousa, Y J Chung, J P Rose, B C Wang | Crystal structure of bacteriophage T7... | |
| 1993 | Jan Balzarini, Sonsoles Velazquez, A San-Felix, Anna Karlsson, M J Perez-Perez, MarĂa-JosĂ© Camarasa, Erik De Clercq | Human immunodeficiency virus type 1-s... | |
| 1993 | Jan Balzarini, Anna Karlsson, MarĂa-JesĂşs PĂ©rez-PĂ©rez, MarĂa-JosĂ© Camarasa, W G Tarpley, Erik De Clercq | Treatment of human immunodeficiency v... | |
| 1993 | Mark A. Wainberg, Z Gu, Q Gao, E Arts, R Geleziunas, S Bour, R Beaulieu, C Tsoukas, J Singer, J Montaner | Clinical correlates and molecular bas... | |
| 1993 | Jan Balzarini, Anna Karlsson, MarĂa-JesĂşs PĂ©rez-PĂ©rez, L Vrang, J Walbers, Haijiang Zhang, Bo Oberg, A-M Vandamme, MarĂa-JosĂ© Camarasa, Erik De Clercq | HIV-1-specific reverse transcriptase ... | |
| 1993 | G T Tan, A Wickramasinghe, S Verma, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan | Sulfonic acid polymers are potent inh... | |
| 1993 | A Hizi, R Tal, M Shaharabany, M J Currens, M R Boyd, Stephen H Hughes, James B McMahon | Specific inhibition of the reverse tr... | |
| 1993 | R Goel, William A Beard, A Kumar, J R Casas-Finet, M P Strub, S J Stahl, M S Lewis, Katarzyna Bebenek, S P Becerra, Thomas A Kunkel | Structure/function studies of HIV-1(1... | |
| 1992 | G T Tan, J F Miller, A D Kinghorn, Stephen H Hughes, J M Pezzuto | HIV-1 and HIV-2 reverse transcriptase... | |
| 1992 | J J DeStefano, R G Buiser, L M Mallaber, P J Fay, Robert A Bambara | Parameters that influence processive ... | RT,Full length or truncated,Specific Activity,Processivity,Molecular Weight,RNase H,All properties |
| 1992 | W M Kati, Kenneth A Johnson, L F Jerva, Karen S Anderson | Mechanism and fidelity of HIV reverse... | |
| 1992 | Alberto Bergamini, CF Perno, Jan Balzarini, M Capozzi, Luciana Marinelli, G Milanese, C D Pesce, R CaliĂł, G Rocchi | Selective inhibition of HIV replicati... | |
| 1992 | R L Mitina, S V Doronin, M I Dobrikov, D R Tabatadze, A S Levina, Olga I Lavrik | Human immunodeficiency virus type 1 r... | |
| 1992 | Q Gao, Z X Gu, Michael A. Parniak, X G Li, Mark A. Wainberg | In vitro selection of variants of hum... | |
| 1992 | J A Coates, Nick Cammack, H J Jenkinson, I M Mutton, B A Pearson, R Storer, J M Cameron, C R Penn | The separated enantiomers of 2'-deoxy... | |
| 1992 | K De Vreese, Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, J Desmyter, Erik De Clercq, J Anné | Resistance of human immunodeficiency ... | |
| 1992 | William C Copeland, M S Chen, Teresa S-F Wang | Human DNA polymerases alpha and beta ... | |
| 1992 | S F Lacey, J E Reardon, E S Furfine, Thomas A Kunkel, Katarzyna Bebenek, Kristin A Eckert, S D Kemp, Brendan A Larder | Biochemical studies on the reverse tr... | |
| 1992 | Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, Masanori Baba, J Desmyter, Erik De Clercq | Kinetics of inhibition of endogenous ... | |
| 1992 | L Ding, Jan Balzarini, Dominique Schols, B Meunier, Erik De Clercq | Anti-human immunodeficiency virus eff... | |
| 1992 | Shunji Izuta, N Shimada, Masatoshi Kitagawa, Motoshi Suzuki, K Kojima, Shonen Yoshida | Inhibitory effects of triphosphate de... | |
| 1992 | N Yamamoto, Dominique Schols, Erik De Clercq, Zeger Debyser, Rudi Pauwels, Jan Balzarini, H Nakashima, Masanori Baba, M Hosoya, Robert Snoeck | Mechanism of anti-human immunodeficie... | |
| 1992 | A Hosmalin, S Kumar, D Barnd, R Houghten, G E Smith, Stephen H Hughes, J A Berzofsky | Immunization with soluble protein-pul... | |
| 1992 | S Loya, R Tal, Stephen H Hughes, A Hizi | The effects of cysteine mutations on ... | |
| 1992 | Jan Balzarini, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Ana San-FĂ©lix, Dominique Schols, CF Perno, A-M Vandamme, MarĂa-JosĂ© Camarasa, Erik De Clercq | 2',5'-Bis-O-(tert-butyldimethylsilyl)... | |
| 1992 | Hong Yu, Myron F Goodman | Comparison of HIV-1 and avian myelobl... | |
| 1992 | D L Mayers, F E McCutchan, E E Sanders-Buell, L I Merritt, S Dilworth, A K Fowler, C A Marks, N M Ruiz, Douglas D Richman, C R Roberts | Characterization of HIV isolates aris... | |
| 1992 | Edward Arnold, A Jacobo-Molina, R G Nanni, R L Williams, Xiaoqing Lu, Jianping Ding, Art D Clark, A Zhang, Andrea L Ferris, Patrick K Clark | Structure of HIV-1 reverse transcript... | |
| 1992 | M Jiang, J Mak, Mark A. Wainberg, Michael A. Parniak, E Cohen, Lawrence Kleiman | Variable tRNA content in HIV-1IIIB. | |
| 1992 | Erik De Clercq | HIV inhibitors targeted at the revers... | |
| 1992 | L A Kohlstaedt, Jianhong Wang, J M Friedman, P A Rice, Thomas A Steitz | Crystal structure at 3.5 A resolution... | |
| 1992 | M Bakhanashvili, A Hizi | Fidelity of the reverse transcriptase... | RT,3-5' exo,All properties |
| 1992 | J A Coates, Nick Cammack, H J Jenkinson, A J Jowett, M I Jowett, B A Pearson, C R Penn, P L Rouse, K C Viner, J M Cameron | (-)-2'-deoxy-3'-thiacytidine is a pot... | |
| 1992 | Zeger Debyser, K De Vreese, Rudi Pauwels, N Yamamoto, J Anné, Erik De Clercq, J Desmyter | Differential inhibitory effects of TI... | |
| 1992 | J Abbotts, Samuel H Wilson | Inhibitors of HIV-1 reverse transcrip... | |
| 1992 | C S Crumpacker | Mechanism of action of foscarnet agai... | |
| 1992 | John W Mellors, Ginger E Dutschman, G J Im, Enzo Tramontano, S R Winkler, Yung-Chi Cheng | In vitro selection and molecular char... | |
| 1992 | G T Tan, A Wickramasinghe, S Verma, R Singh, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan | Potential anti-AIDS naphthalenesulfon... | |
| 1992 | Paul L Boyer, Andrea L Ferris, Stephen H Hughes | Mutational analysis of the fingers do... | |
| 1992 | P Kellam, Charles A B Boucher, Brendan A Larder | Fifth mutation in human immunodeficie... | |
| 1992 | Brendan A Larder | 3'-Azido-3'-deoxythymidine resistance... | |
| 1992 | Mark A. Wainberg, R G Margolese | Strategies in the treatment of AIDS a... | |
| 1992 | A Basu, K K Ahluwalia, S Basu, Mukund J Modak | Identification of the primer binding ... | |
| 1992 | V V Sardana, E A Emini, L Gotlib, D J Graham, D W Lineberger, W J Long, A J Schlabach, J A Wolfgang, J H Condra | Functional analysis of HIV-1 reverse ... | |
| 1992 | J P Ji, Lawrence A Loeb | Fidelity of HIV-1 reverse transcripta... | |
| 1992 | I I Fedorov, E M Kazmina, N A Novicov, Galina V Gurskaya, A V Bochkarev, M V Jasko, L S Victorova, M K Kukhanova, Jan Balzarini, Erik De Clercq | 3'-C-branched 2'-deoxy-5-methyluridin... | |
| 1992 | Zeger Debyser, Rudi Pauwels, Koen Andries, Erik De Clercq | Specific HIV-1 reverse transcriptase ... | |
| 1992 | Jan Balzarini, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Ana San-FĂ©lix, MarĂa-JosĂ© Camarasa, I C Bathurst, P J Barr, Erik De Clercq | Kinetics of inhibition of human immun... | |
| 1992 | J A Peliska, Stephen J Benkovic | Mechanism of DNA strand transfer reac... | |
| 1992 | Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg | Novel mutation in the human immunodef... | |
| 1992 | Z Hostomsky, Z Hostomska, T B Fu, J Taylor | Reverse transcriptase of human immuno... | |
| 1992 | J C Boyer, Katarzyna Bebenek, Thomas A Kunkel | Unequal human immunodeficiency virus ... | |
| 1992 | Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Y Engelborghs, Paul A J Janssen, Erik De Clercq | Allosteric inhibition of human immuno... | |
| 1992 | L A Kohlstaedt, Thomas A Steitz | Reverse transcriptase of human immuno... | |
| 1992 | A Basu, S Basu, Mukund J Modak | Structure-activity analyses of HIV-1 ... | |
| 1992 | Erik De Clercq | New perspectives for the chemotherapy... | |
| 1992 | Jan Balzarini, MarĂa-JesĂşs PĂ©rez-PĂ©rez, Ana San-FĂ©lix, Sonsoles Velazquez, MarĂa-JosĂ© Camarasa, Erik De Clercq | [2',5'-Bis-O-(tert-butyldimethylsilyl... | |
| 1992 | J E Reardon | Human immunodeficiency virus reverse ... | |
| 1992 | M B Vasudevachari, C Battista, H C Lane, M C Psallidopoulos, B Zhao, J Cook, J R Palmer, D L Romero, W G Tarpley, N P Salzman | Prevention of the spread of HIV-1 inf... | |
| 1992 | Tsuyoshi Yamaguchi, Shunji Izuta, Motoshi Suzuki, Shonen Yoshida, Akio Matsukage, Mineo Saneyoshi | Inhibitory effects of 2'-deoxy-5-styr... | |
| 1992 | M M Huang, Norman Arnheim, Myron F Goodman | Extension of base mispairs by Taq DNA... | |
| 1992 | F Boulerice, R Geleziunas, S Bour, H L Li, M D'Addario, A Roulston, J Hiscott, Mark A. Wainberg | Differential susceptibilities of U-93... | |
| 1992 | V Gopalakrishnan, J A Peliska, Stephen J Benkovic | Human immunodeficiency virus type 1 r... | RT,Terminal Transferase,RNase H,All properties |
| 1991 | G T Tan, A D Kinghorn, Stephen H Hughes, J M Pezzuto | Psychotrine and its O-methyl ether ar... | |
| 1991 | R S Goody, B MĂĽller, Tobias Restle | Factors contributing to the inhibitio... | |
| 1991 | P Hafkemeyer, K Neftel, R Hobi, A Pfaltz, H Lutz, K LĂĽthi, Federico Focher, Silvio Spadari, Ulrich HĂĽbscher | HP 0.35, a cephalosporin degradation ... | RT,RNase H,All properties |
| 1991 | M Tisdale, T Schulze, Brendan A Larder, K Moelling | Mutations within the RNase H domain o... | |
| 1991 | M H St Clair, J L Martin, G Tudor-Williams, M C Bach, C L Vavro, D M King, P Kellam, S D Kemp, Brendan A Larder | Resistance to ddI and sensitivity to ... | |
| 1991 | Jan Balzarini, Antonin Holy, J Jindrich, H Dvorakova, Z Hao, Robert Snoeck, Piet Herdewijn, D G Johns, Erik De Clercq | 9-[(2RS)-3-fluoro-2-phosphonylmethoxy... | |
| 1991 | Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Michael Kukla, Paul A J Janssen, Erik De Clercq | An antiviral target on reverse transc... | |
| 1991 | D Richman, C K Shih, I Lowy, J Rose, P Prodanovich, S Goff, J Griffin | Human immunodeficiency virus type 1 m... | |
| 1991 | A S De Groot, M Clerici, A Hosmalin, Stephen H Hughes, D Barnd, C W Hendrix, R Houghten, G M Shearer, J A Berzofsky | Human immunodeficiency virus reverse ... | |
| 1991 | Olga I Lavrik | Oligonucleotides and their derivative... | |
| 1991 | E B Kopp, J J Miglietta, A G Shrutkowski, C K Shih, P M Grob, M T Skoog | Steady state kinetics and inhibition ... | KM,kcat,All properties |
| 1991 | Mark Cushman, P L Wang, S H Chang, C Wild, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen | Preparation and anti-HIV activities o... | |
| 1991 | P R Johnson, T E Hamm, S Goldstein, S Kitov, V M Hirsch | The genetic fate of molecularly clone... | |
| 1991 | Stuart F J Le Grice, T Naas, B Wohlgensinger, O Schatz | Subunit-selective mutagenesis indicat... | |
| 1991 | S P Becerra, A Kumar, M S Lewis, S G Widen, J Abbotts, E M Karawya, Stephen H Hughes, J Shiloach, Samuel H Wilson, M S Lewis | Protein-protein interactions of HIV-1... | |
| 1991 | Robert W Sobol, R J Suhadolnik, A Kumar, B J Lee, D L Hatfield, Samuel H Wilson | Localization of a polynucleotide bind... | |
| 1991 | J G Baillon, N T Nashed, A Kumar, Samuel H Wilson, Donald M Jerina | A leucine zipper-like motif may media... | |
| 1991 | Mark Cushman, S Kanamathareddy, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen | Synthesis and anti-HIV activities of ... | |
| 1991 | E S Furfine, J E Reardon | Reverse transcriptase.RNase H from th... | RT,All properties |
| 1991 | K B Frank, G J Noll, E V Connell, I S Sim | Kinetic interaction of human immunode... | |
| 1991 | J H Nunberg, W A Schleif, E J Boots, J A O'Brien, J C Quintero, J M Hoffman, E A Emini, M E Goldman | Viral resistance to human immunodefic... | |
| 1991 | Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, R T Walker, S Mori | Highly potent and selective inhibitio... | |
| 1991 | A Jacobo-Molina, Edward Arnold | HIV reverse transcriptase structure-f... | |
| 1991 | Brendan A Larder, K E Coates, S D Kemp | Zidovudine-resistant human immunodefi... | |
| 1991 | J Abbotts, M Jaju, Samuel H Wilson | Thermodynamics of A:G mismatch poly(d... | |
| 1991 | Mark A. Wainberg, R Rooke, M Tremblay, Xincang Li, Michael A. Parniak, Q Gao, X J Yao, C Tsoukas, J Montaner, M Fanning, J Ruedy | Clinical significance and characteriz... | |
| 1991 | Erik De Clercq | Chemotherapy of the acquired immune d... | |
| 1991 | F Boulerice, X G Li, A Lvovich, Mark A. Wainberg | Recovery of infectious human immunode... | |
| 1991 | A Hizi, R Tal, Stephen H Hughes | Mutational analysis of the DNA polyme... | |
| 1991 | J E Reardon, E S Furfine, N Cheng | Human immunodeficiency virus reverse ... | |
| 1991 | A DeVico, R C Montelaro, R C Gallo, M G Sarngadharan | Purification and partial characteriza... | RT,Full length or truncated,3-5' exo,Nucleotide Substitution Rate,RNase H,All properties |
| 1991 | Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, H Nakashima, S Mori | Potent and selective inhibition of hu... | |
| 1990 | M Tremblay, K Numazaki, H Goldman, Mark A. Wainberg | Infection of human thymic lymphocytes... | |
| 1990 | Stuart F J Le Grice, F GrĂĽninger-Leitch | Rapid purification of homodimer and h... | |
| 1990 | A I Glukhov, S A Gordeev, S V Vinogradov, V I Kiselev, V M Kramarov, O I Kiselev, E S Severin | Amplification of DNA sequences of Eps... | |
| 1990 | A Hizi, Stephen H Hughes, M Shaharabany | Mutational analysis of the ribonuclea... | |
| 1990 | Z Hao, D A Cooney, D Farquhar, CF Perno, K Zhang, R Masood, Y Wilson, N R Hartman, Jan Balzarini, D G Johns | Potent DNA chain termination activity... | |
| 1990 | W E Müller, E Matthes, P Reuter, R Wenger, K Friese, Y Kuchino, H C Schröder | Effect of nonviable preparations from... | |
| 1990 | Mark A. Wainberg, Bonnie Spira, G Bleau, R Thomas | Inactivation of human immunodeficienc... | |
| 1990 | Erik De Clercq | Targets and strategies for the antivi... | |
| 1990 | S P Becerra, G M Clore, A M Gronenborn, A R Karlström, S J Stahl, Samuel H Wilson, P T Wingfield | Purification and characterization of ... | |
| 1990 | Erik De Clercq | Selective virus inhibitors. | |
| 1990 | Andrea L Ferris, A Hizi, S D Showalter, S Pichuantes, L Babe, C S Craik, Stephen H Hughes | Immunologic and proteolytic analysis ... | |
| 1990 | V J Merluzzi, K D Hargrave, M Labadia, K Grozinger, M Skoog, J C Wu, C K Shih, K Eckner, S Hattox, J Adams | Inhibition of HIV-1 replication by a ... | |
| 1990 | Padmini S Kedar, J Abbotts, T Kovács, K Lesiak, P Torrence, Samuel H Wilson | Mechanism of HIV reverse transcriptas... | |
| 1990 | J E Reardon, W H Miller | Human immunodeficiency virus reverse ... | KM,kcat,All properties |
| 1990 | A M Barber, A Hizi, J V Maizel, Stephen H Hughes | HIV-1 reverse transcriptase: structur... | |
| 1990 | M Tremblay, K Numazaki, X G Li, M Gornitsky, J Hiscott, Mark A. Wainberg | Resistance to infection by HIV-1 of p... | |
| 1990 | R Rooke, M Tremblay, Mark A. Wainberg | AZT (zidovudine) may act postintegrat... | |
| 1990 | Brendan A Larder, B Chesebro, Douglas D Richman | Susceptibilities of zidovudine-suscep... | |
| 1990 | M Ricchetti, H Buc | Reverse transcriptases and genomic va... | |
| 1990 | F Boulerice, Mark A. Wainberg | Inhibition by AZT of HIV-1 replicatio... | |
| 1990 | K J Williams, Lawrence A Loeb, M Fry | Synthesis of DNA by human immunodefic... | |
| 1989 | M Tremblay, M Gornitsky, Mark A. Wainberg | Active replication of human immunodef... | |
| 1989 | Fred W Perrino, Bradley D Preston, L L Sandell, Lawrence A Loeb | Extension of mismatched 3' termini of... | |
| 1989 | H E Huber, J M McCoy, J S Seehra, Charles C Richardson | Human immunodeficiency virus 1 revers... | Processivity,3-5' exo,5-3' exo,KM,Kd,RNase H,All properties |
| 1989 | A Basu, R S Tirumalai, Mukund J Modak | Substrate binding in human immunodefi... | |
| 1989 | B MĂĽller, Tobias Restle, S Weiss, M Gautel, G Sczakiel, R S Goody | Co-expression of the subunits of the ... | |
| 1989 | M Ito, Masanori Baba, A Sato, K Hirabayashi, F Tanabe, S Shigeta, Erik De Clercq | Tumor necrosis factor enhances replic... | |
| 1989 | K Numazaki, X Q Bai, H Goldman, I Wong, Bonnie Spira, Mark A. Wainberg | Infection of cultured human thymic ep... | |
| 1989 | Masanori Baba, Dominique Schols, H Nakashima, Rudi Pauwels, G Parmentier, D K Meijer, Erik De Clercq | Selective activity of several cholic ... | |
| 1989 | Dominique Schols, Masanori Baba, Rudi Pauwels, Erik De Clercq | Flow cytometric method to demonstrate... | |
| 1989 | M Tremblay, Mark A. Wainberg | Susceptibility of EBV-carrying B cell... | |
| 1989 | C Majumdar, C A Stein, J S Cohen, S Broder, Samuel H Wilson | Stepwise mechanism of HIV reverse tra... | |
| 1989 | Masanori Baba, Hiromichi Tanaka, Erik De Clercq, Rudi Pauwels, Jan Balzarini, Dominique Schols, H Nakashima, CF Perno, R T Walker, T Miyasaka | Highly specific inhibition of human i... | |
| 1989 | Erik De Clercq | Potential drugs for the treatment of ... | |
| 1989 | Brendan A Larder, S D Kemp | Multiple mutations in HIV-1 reverse t... | |
| 1989 | A Hizi, A Barber, Stephen H Hughes | Effects of small insertions on the RN... | |
| 1988 | J D Roberts, Katarzyna Bebenek, Thomas A Kunkel | The accuracy of reverse transcriptase... | |
| 1988 | E M Wondrak, J Löwer, R Kurth | Inhibition of HIV-1 RNA-dependent DNA... | |
| 1988 | Masanori Baba, Dominique Schols, Rudi Pauwels, Jan Balzarini, Erik De Clercq | Fuchsin acid selectively inhibits hum... | |
| 1988 | Sujit Roy, L Fitz-Gibbon, L Poulin, Mark A. Wainberg | Infection of human monocytes/macropha... | |
| 1988 | Erik De Clercq | Perspectives for the chemotherapy of ... | |
| 1988 | M Tremblay, L Fitz-Gibbon, Mark A. Wainberg | Heterogeneity of HIV-1 replication an... | |
| 1988 | Bradley D Preston, B J Poiesz, Lawrence A Loeb | Fidelity of HIV-1 reverse transcriptase. | |
| 1988 | A Hizi, C McGill, Stephen H Hughes | Expression of soluble, enzymatically ... | |
| 1988 | Masanori Baba, Rudi Pauwels, Jan Balzarini, J Arnout, J Desmyter, Erik De Clercq | Mechanism of inhibitory effect of dex... | |
| 1987 | Brendan A Larder, D J Purifoy, K L Powell, G Darby | Site-specific mutagenesis of AIDS vir... | |
| 1987 | M Ito, H Nakashima, Masanori Baba, Rudi Pauwels, Erik De Clercq, S Shigeta, N Yamamoto | Inhibitory effect of glycyrrhizin on ... | |
| 1986 | H A Blough, Rudi Pauwels, Erik De Clercq, J Cogniaux, S Sprecher-Goldberger, L Thiry | Glycosylation inhibitors block the ex... | |
| 1986 | F di Marzo Veronese, T D Copeland, A L DeVico, R Rahman, S Oroszlan, R C Gallo, M G Sarngadharan | Characterization of highly immunogeni... | |
| 1986 | M M Lightfoote, J E Coligan, T M Folks, A S Fauci, M A Martin, S Venkatesan | Structural characterization of revers... | |
| 1986 | M S Johnson, M A McClure, D F Feng, J Gray, R F Doolittle | Computer analysis of retroviral pol g... | |
| 1985 | A D Hoffman, B Banapour, J A Levy | Characterization of the AIDS-associat... |
Protein information: Uniprot Q8Q292 search for HIV RT at UniProt
Sequence information: NCBI nucleotides European nucleotide archive