HIV RT
From
HIV
Welcome to the Polymerase Page
This page presents all the information in Polbase for HIV RT.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
HIV RT
is a family RT enzyme
from
HIV.
Selected Properties for HIV RT: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| No (4) | No (1) | 8.0e-06-4.7e-03 errors/bp (3) | 2.6e-05-3.2e-03 errors/bp (5) | 7.5e-05-8.0e-02 errors/bp (4) |
| Year | Authors | Title | Results by property |
|---|---|---|---|
| Sherine S L Chan, Janine H Santos, Joel N Meyer, Bhaskar S Mandavilli, Dennis L Cook, Consuelo L McCash, Grace E Kissling, Abraham Nyska, Julie F Foley, Bennett Van Houten, William C Copeland, Vernon E Walker, Kristine L Witt, Jack B Bishop | Mitochondrial toxicity in hearts of C... | ||
| G T Tan, J M Pezzuto, A D Kinghorn, Stephen H Hughes | Evaluation of natural products as inh... | ||
| Maria Letizia Barreca, Laura De Luca, Nunzio Iraci, Angela Rao, Stefania Ferro, Giovanni Maga, Alba Chimirri | Structure-based pharmacophore identif... | ||
| Chen Liang, Mark A. Wainberg | The role of Tat in HIV-1 replication:... | ||
| Mark A. Wainberg, S Bour, R Geleziunas, Z Bentwich | [Antiviral strategies in the replicat... | ||
| Jorge L Martínez-Cajas, Nitika Pant-Pai, Marina B Klein, Mark A. Wainberg | Role of genetic diversity amongst HIV... | ||
| P Hafkemeyer, K A Neftel, Ulrich Hübscher | HIV-reverse transcriptase and human D... | ||
| Paul J Lewi, Marc R De Jonge, Frits F D Daeyaert, Luc Koymans, Maarten H Vinkers, Jan Heeres, Paul A J Janssen, Edward Arnold, Kalyan Das, Art D Clark, Stephen H Hughes, Paul L Boyer, Marie-Pierre P De Béthune, Rudi Pauwels, Koen Andries, Michael Kukla, Donald W Ludovici, Bart De Corte, Robert W Kavash, Chih Y Ho, Paul J Lewis | On the detection of multiple-binding ... | ||
| N Düzgünes, S Simões, V Slepushkin, E Pretzer, J J Rossi, Erik De Clercq, V P Antao, M L Collins, M C de Lima | Enhanced inhibition of HIV-1 replicat... | ||
| Erik De Clercq | Perspectives of non-nucleoside revers... | ||
| Erik De Clercq | Novel compounds in preclinical/early ... | ||
| Erik De Clercq | New developments in anti-HIV chemothe... | ||
| Rudi Pauwels, M P de Bethune, Koen Andries, Paul Stoffels, P Janssen, Erik De Clercq | Discovery, development and characteri... | ||
| Erik De Clercq, Robert Snoeck | [Current acquisitions in antiviral dr... | ||
| Erik De Clercq | Perspectives for the chemotherapy of ... | ||
| Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari | Structural determinants of HIV-1 reve... | ||
| N Gashnikova, O Plyasunova, Y Kiseleva, N Fedyuk, A Pokrovsky | In vitro study of resistance-associat... | ||
| María-Cruz Bonache, Cristina Chamorro, Sonsoles Velázquez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Ana San-Félix | N-3 substituted TSAO derivatives as a... | ||
| 2013 | Mikhail S Novikov, Vladimir T Valuev-Elliston, Denis A Babkov, Maria P Paramonova, Alexander V Ivanov, Sergey A Gavryushov, Anastasia L Khandazhinskaya, Sergey N Kochetkov, Christophe Pannecouque, Graciela Andrei, Robert Snoeck, Jan Balzarini, Katherine L Seley-Radtke | N(1),N(3)-disubstituted uracils as no... | |
| 2013 | Erik De Clercq | The Nucleoside Reverse Transcriptase ... | |
| 2013 | Ravindra K Gupta, DA Van de Vijver, S Manicklal, MA Wainberg | Evolving uses of oral reverse transcr... | |
| 2013 | Xuwang Chen, Yuanyuan Li, Shufang Ding, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Huiqing Liu, Xinyong Liu | Discovery of Piperidine-Linked Pyridi... | |
| 2013 | R S K Vijayan, Edward Arnold, Kalyan Das | Molecular dynamics study of HIV-1 RT-... | |
| 2013 | Matthew McCallum, Maureen Oliveira, Ruxandra-Ilinca Ibanescu, Victor G Kramer, Daniela D Moisi, Eugene L Asahchop, Bluma G Brenner, Richard Harrigan, Hongtao Xu, Mark A. Wainberg | Basis for the Early and Preferential ... | |
| 2013 | Shiqiong Yang, Christophe Pannecouque, Dirk Daelemans, Xiao-Dong Ma, Yang Liu, Fen-Er Chen, Erik De Clercq | Molecular design, synthesis and biolo... | |
| 2013 | Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd | Inhibition of HIV-1 Reverse Transcrip... | |
| 2013 | Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Xinyong Liu | Novel piperidinylamino-diarylpyrimidi... | |
| 2013 | Venkata Ramana Sirivolu, Sanjeev Kumar V Verneka, Tatiana Ilina, Nataliya S Myshakina, Michael A. Parniak, Zhengqiang Wang | Clicking 3'-azidothymidine into novel... | |
| 2013 | Ye Tian, Diwakar Rai, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Huiqing Liu, Xinyong Liu | Design, Synthesis, and Biological Eva... | |
| 2013 | Kalyan Das, Edward Arnold | HIV-1 reverse transcriptase and antiv... | |
| 2013 | Linda L Dunn, Paul L Boyer, Patrick K Clark, Stephen H Hughes | Mutations in HIV-1 reverse transcript... | |
| 2013 | Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Rita S Schildknecht, Hongtao Xu, Simani Gaseitswe, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg | The preferential selection of K65R in... | |
| 2013 | J-H Lee, Atsuko Hachiya, S-K Shin, J Lee, Hiroyuki Gatanaga, Shinichi Oka, Karen A Kirby, Yee Tsuey Ong, Stefan G Sarafianos, William R Folk, Wangdon Yoo, Sun Pyo Hong, S-O Kim | Restriction fragment mass polymorphis... | |
| 2013 | Daniel G Kuroda, Joseph David Bauman, J Reddy Challa, Disha Patel, Thomas Troxler, Kalyan Das, Edward Arnold, Robin M Hochstrasser | Snapshot of the equilibrium dynamics ... | |
| 2013 | Dongyue Li, Peng Zhan, Huiqing Liu, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2013 | Kalyan Das, Edward Arnold | HIV-1 reverse transcriptase and antiv... | |
| 2013 | John E Tavis, Xiaohong Cheng, Yuan Hu, Michael Totten, Feng Cao, Eleftherios Michailidis, Rajeev Aurora, Marvin J Meyers, E Jon Jacobsen, Michael A. Parniak, Stefan G Sarafianos | The hepatitis B virus ribonuclease h ... | |
| 2013 | Joseph David Bauman, Disha Patel, Chhaya Dharia, Marc Fromer, Sameer Ahmed, Yulia Volovik Frenkel, J Thomas Eck, William C Ho, Kalyan Das, Aaron J Shatkin, Edward Arnold | Detecting allosteric sites of HIV-1 r... | |
| 2013 | Hong-Tao Xu, Susan P Colby-Germinario, Eugene L Asahchop, Maureen Oliveira, Matthew McCallum, Susan M Schader, Yingshan Han, Yudong Quan, Stefan G Sarafianos, Mark A. Wainberg | The Effect of Mutations at Position E... | |
| 2013 | Hai-Qiu Wu, Zi-Hong Yan, Wen-Xue Chen, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Dirk Daelemans, Christophe Pannecouque | Towards new C6-rigid S-DABO HIV-1 rev... | |
| 2013 | Jan Balzarini, Graciela Andrei, Emanuela Balestra, Dana Huskens, Christophe Vanpouille, Andrea Introini, Sonia Zicari, Sandra Liekens, Robert Snoeck, Antonín Holý, CF Perno, Leonid Margolis, Dominique Schols | A Multi-targeted Drug Candidate with ... | |
| 2013 | Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno Marchand, Maxwell D Leslie, Andrew D Huber, Yee Tsuey Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Hypersusceptibility mechanism of Teno... | |
| 2013 | Mariela Bollini, Kathleen M Frey, José A Cisneros, Krasimir A Spasov, Kalyan Das, Joseph David Bauman, Edward Arnold, Karen S Anderson, William L Jorgensen | Extension into the entrance channel o... | |
| 2013 | A Heredia, CE Davis, MS Reitz, NM Le, MA Wainberg, JS Foulke, LX Wang, RR Redfield | Targeting of the Purine Biosynthesis ... | |
| 2013 | Karen A Kirby, Eleftherios Michailidis, Tracy L Fetterly, MA Steinbach, Kamalendra Singh, Bruno Marchand, Maxwell D Leslie, Ariel N Hagedorn, Eiichi N Kodama, Victor E Marquez, Stephen H Hughes, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Effects of 4' - and 2-Substitutions o... | |
| 2012 | Wenwen Chen, Peng Zhan, Erik De Clercq, Xinyong Liu | Recent progress in small molecule CCR... | |
| 2012 | Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valeria Famiglini, Sandro Cosconati, Giovanni Maga, Alberta Samuele, Emmanuel Gonzales, B Clotet, Dominique Schols, Jose Este, Ettore Novellino, Romano Silvestri | New Nitrogen Containing Substituents ... | |
| 2012 | Martin T Christen, Lakshmi Menon, Nataliya S Myshakina, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima | Structural basis of the allosteric in... | |
| 2012 | Xuwang Chen, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2012 | Shuang-Xi Gu, Zhi-Ming Li, Xiao-Dong Ma, Shi-Qiong Yang, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Chiral resolution, absolute configura... | |
| 2012 | Xincang Li, Peng Zhan, Erik De Clercq, Xinyong Liu | The HIV-1 Non-Nucleoside Reverse Tran... | |
| 2012 | Changfu Yang, Shuyuan Liu, Taisong Zhang, Yaping Hou, Xiaoli Liu, Yun Gao, Guang Yang, Zhen Wang, Huayun Chen, Ming Li, Zhenyu Zhu | Transmitted antiretroviral drug resis... | |
| 2012 | Paul L Boyer, Patrick K Clark, Stephen H Hughes | HIV-1 and HIV-2 Reverse Transcriptase... | |
| 2012 | Victor G Kramer, Susan M Schader, Maureen Oliveira, Susan P Colby-Germinario, Daniel A Donahue, Diane N Singhroy, Randy Tressler, Richard D Sloan, Mark A. Wainberg | Maraviroc and other HIV-1 entry inhib... | |
| 2012 | Peng Zhan, Wenmin Chen, Zhongjie Li, Xincang Li, Xuwang Chen, Ye Tian, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Discovery of novel 2-(3-(2-chlorophen... | |
| 2012 | Sergio R Ribone, Volker Leen, Marcela Madrid, Wim Dehaen, Dirk Daelemans, Christophe Pannecouque, Margarita C Briñón | Synthesis, biological evaluation and ... | |
| 2012 | Eleftherios Michailidis, Kamlendra Singh, Emily M Ryan, Atsuko Hachiya, Yee Tsuey Ong, Karen A Kirby, Bruno Marchand, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Effect of translocation defective rev... | |
| 2012 | Dongyue Li, Peng Zhan, Erik De Clercq, Xinyong Liu | Strategies for the design of HIV-1 no... | |
| 2012 | Barry C Johnson, Gary T Pauly, Ganesha Rai, Disha Patel, Joseph David Bauman, Heather L Baker, Kalyan Das, Joel P Schneider, David J Maloney, Edward Arnold, Craig J Thomas, Stephen H Hughes | A comparison of the ability of rilpiv... | |
| 2012 | Wei-Shau Hu, Stephen H Hughes | HIV-1 Reverse Transcription. | |
| 2012 | Kalyan Das, Sergio E Martinez, Joseph David Bauman, Edward Arnold | HIV-1 reverse transcriptase complex w... | |
| 2012 | K O François, Jan Balzarini | Potential of carbohydrate-binding age... | |
| 2012 | Eva-María Priego, Anna Karlsson, Federico Gago, María-José Camarasa, Jan Balzarini, María-Jesús Pérez-Pérez | Recent advances in thymidine kinase 2... | |
| 2012 | Serdal Kirmizialtin, Virginia Nguyen, Kenneth A Johnson, Ron Elber | How conformational dynamics of DNA po... | |
| 2012 | Marco Radi, Mafalda Pagano, Luigi Franchi, Daniele Castagnolo, Silvia Schenone, Gianni Casaluce, Claudio Zamperini, Elena Dreassi, Giovanni Maga, Alberta Samuele, Encarna Gonzalo, B Clotet, José A Esté, Maurizio Botta | Synthesis, Biological Activity, and A... | |
| 2012 | Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd | DNA Polymerase β Gap-filling Transles... | |
| 2012 | Zhongjie Li, Yuan Cao, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Arylazolylthioacetanilide. Part 11: D... | |
| 2012 | Dante Rotili, Alberta Samuele, Domenico Tarantino, Rino Ragno, Ira Musmuca, Flavio Ballante, Giorgia Botta, Ludovica Morera, Marco Pierini, Roberto Cirilli, Maxim B Nawrozkij, Emmanuel Gonzalez, B Clotet, Marino Artico, José A Esté, Giovanni Maga, Antonello Mai | 2-(Alkyl/Aryl)Amino-6-Benzylpyrimidin... | |
| 2012 | Ye Tian, Peng Zhan, Diwakar Rai, Jiyan Zhang, Erik De Clercq, Xinyong Liu | Recent advances in the research of 2,... | |
| 2012 | Shiqiong Yang, Fen-Er Chen, Erik De Clercq | Dihydro-alkoxyl-benzyl-oxopyrimidine ... | |
| 2012 | Kamalendra Singh, Bruno Marchand, Devendra K Rai, Bechan Sharma, Eleftherios Michailidis, Emily M Ryan, Kayla B Matzek, Maxwell D Leslie, Ariel N Hagedorn, Zhongjie Li, Pieter R Norden, Atsuko Hachiya, Michael A. Parniak, Hong-Tao Xu, Mark A. Wainberg, Stefan G Sarafianos | Biochemical Mechanism of HIV-1 Resist... | |
| 2012 | Peng Zhan, Xincang Li, Zhongjie Li, Xuwang Chen, Ye Tian, Wenmin Chen, Xinyong Liu, Christophe Pannecouque, Erik De Clercq | Structure-based bioisosterism design,... | |
| 2012 | Xuwang Chen, Peng Zhan, Xin Liu, Ziheng Cheng, Caicai Meng, Siyuan Shao, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Design, synthesis, anti-HIV evaluatio... | |
| 2012 | Christophe Vanpouille, Andrea Lisco, Andrea Introini, Jean-Charles Grivel, Arshi Munawwar, Melanie Merbah, Raymond F Schinazi, Marco Derudas, Christopher McGuigan, Jan Balzarini, Leonid Margolis | Exploiting the anti-HIV-1 activity of... | |
| 2012 | Christal D Sohl, Rajesh Kasiviswanathan, Jiae Kim, Ugo Pradere, Raymond F Schinazi, William C Copeland, Hiroyuki Mitsuya, Masanori Baba, Karen S Anderson | Balancing Antiviral Potency and Host ... | |
| 2012 | Tatiana Ilina, Krystal Labarge, Stefan G Sarafianos, Rieko Ishima, Michael A. Parniak | Inhibitors of HIV-1 Reverse Transcrip... | |
| 2012 | Karen A Kirby, Bruno Marchand, Yee Tsuey Ong, Tanyaradzwa P Ndongwe, Atsuko Hachiya, Eleftherios Michailidis, Maxwell D Leslie, Daniel V Sietsema, Tracy L Fetterly, Christopher A Dorst, Kamalendra Singh, Zhengqiang Wang, Michael A. Parniak, Stefan G Sarafianos | Structural and Inhibition Studies of ... | |
| 2012 | Atsuko Hachiya, Bruno Marchand, Karen A Kirby, Eleftherios Michailidis, Xiongying Tu, Krzysztof Palczewski, Yee Tsuey Ong, Zhongjie Li, Daniel T Griffin, Matthew M Schuckmann, Junko Tanuma, Shinichi Oka, Kamalendra Singh, Eiichi N Kodama, Stefan G Sarafianos | HIV-1 reverse transcriptase (RT) poly... | |
| 2011 | Atsuko Hachiya, Eiichi N Kodama, Matthew M Schuckmann, Karen A Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G Sarafianos | K70Q adds high-level tenofovir resist... | |
| 2011 | Tao Dong, Yongqing Zhang, Ke Yi Xu, Huiping Yan, Ian James, Yanchun Peng, Marie-Eve Blais, Silvana Gaudieri, Xinyue Chen, Wenhui Lun, Hao Wu, Wen Yan Qu, Tim Rostron, Ning Li, Yu Mao, Simon Mallal, Xiaoning Xu, Andrew McMichael, Mina John, Sarah L Rowland-Jones | Extensive HLA-driven viral diversity ... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Mathieu Metifiot, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | 3-Hydroxypyrimidine-2,4-diones as an ... | |
| 2011 | Mark A. Wainberg, Daniela D Moisi, Maureen Oliveira, Thomas D'Aquin Toni, Bluma G Brenner | Transmission dynamics of the M184V dr... | |
| 2011 | Qingguo Gong, Lakshmi Menon, Tatiana Ilina, Lena G Miller, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima | Interaction of HIV-1 reverse transcri... | |
| 2011 | Bluma G Brenner, Matthew Lowe, Daniela D Moisi, Isabelle Hardy, Simon Gagnon, Hugues Charest, Jean Guy Baril, Mark A. Wainberg, Michel Roger | Subtype diversity associated with the... | |
| 2011 | Hong-Tao Xu, Eugene L Asahchop, Maureen Oliveira, Peter K Quashie, Yudong Quan, Bluma G Brenner, Mark A. Wainberg | Compensation by the E138K mutation in... | |
| 2011 | Eugene L Asahchop, Maureen Oliveira, Mark A. Wainberg, Bluma G Brenner, Daniela D Moisi, Thomas D'Aquin Toni, Cecile L Tremblay | Characterization of the E138K resista... | |
| 2011 | Brian J Scarth, Kirsten L White, James M Chen, Eric B Lansdon, S Swaminathan, Michael D Miller, Matthias Götte | Mechanism of resistance to GS-9148 co... | |
| 2011 | Zhinan Jin, Jerome Deval, Kenneth A Johnson, David C Swinney | Characterization of the elongation co... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | N-3 Hydroxylation of Pyrimidine-2,4-d... | |
| 2011 | Xiao-Dong Ma, Shi-Qiong Yang, Shuang-Xi Gu, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV activity of ar... | |
| 2011 | Yuan Yuan, Hui Xing, Xiao-Yu Wang, Chun-hua Liu, Li-Ting Yang, Ben-Feng Zheng, Xia Wang, Yu-Hua Ruan, Zhe Wang, Hong-wei Liu, Yi-ming Shao | [The prevalence of HIV-1 drug resista... | |
| 2011 | Mikhail S Novikov, Olga N Ivanova, Alexander V Ivanov, Alexander A Ozerov, Vladimir T Valuev-Elliston, Kartik Temburnikar, Galina V Gurskaya, Sergey N Kochetkov, Christophe Pannecouque, Jan Balzarini, Katherine L Seley-Radtke | 1-[2-(2-Benzoyl- and 2-benzylphenoxy)... | |
| 2011 | Jing-Rong Ye, Lei Guo, Hong-Yan Lu, Ruo-Lei Xin, Yi Zeng | [Genotypic resistance mutations to an... | |
| 2011 | Brian J Scarth, Suzanne McCormick, Matthias Götte | Effects of mutations F61A and A62V in... | |
| 2011 | Chandravanu Dash, Yousef Ahmadibeni, Michael J Hanley, Jui Pandhare, Mathias Gotte, Stuart F J Le Grice, Keykavous Parang | Inhibition of multi-drug resistant HI... | |
| 2011 | Anick Auger, Greg L Beilhartz, Siqi Zhu, Elizabeth Cauchon, Jean-Pierre Falgueyret, Jay A Grobler, Maryam Ehteshami, Matthias Götte, Roman A Melnyk | Impact of primer-induced conformation... | |
| 2011 | Alberta Samuele, Sara Bisi, Alexandra Kataropoulou, Giuseppe La Regina, Francesco Piscitelli, Valerio Gatti, Romano Silvestri, Giovanni Maga | Mechanism of interaction of novel ind... | |
| 2011 | Matthew W Kellinger, Kenneth A Johnson | Role of induced fit in limiting discr... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | 6-Benzoyl-3-hydroxypyrimidine-2,4-dio... | |
| 2011 | Matthias Götte | Initiation of HIV reverse transcripti... | |
| 2011 | Kalyan Das, Joseph David Bauman, Angela S Rim, Chhaya Dharia, Arthur D Clark, María-José Camarasa, Jan Balzarini, Edward Arnold | Crystal structure of tert-butyldimeth... | |
| 2011 | Brian D Herman, Raymond F Schinazi, Hong-Wang Zhang, James H Nettles, Richard Stanton, Mervi Detorio, Aleksandr Obikhod, Ugo Pradère, Steven J Coats, John W Mellors, Nicolas Sluis-Cremer | Substrate mimicry: HIV-1 reverse tran... | |
| 2011 | Allison K Delong, Mingham Wu, Diane Bennett, Neil Parkin, Zhijin Wu, Joseph W Hogan, Rami Kantor | Sequence Quality Analysis Tool (SQUAT... | |
| 2011 | Stefania Butini, Sandra Gemma, Margherita Brindisi, Giuseppe Borrelli, Isabella Fiorini, Alberta Samuele, Aristotele Karytinos, Marcella Facchini, Andrea Lossani, Samantha Zanoli, Giuseppe Campiani, Ettore Novellino, Federico Focher, Giovanni Maga | Enantioselective binding of second ge... | |
| 2011 | Peibin Zeng, Jingxing Wang, Yi Huang, Xiaoming Guo, Jinming Li, Guoxin Wen, Tonghan Yang, Zhongqiao Yun, Miao He, Yu Liu, Yuzhe Yuan, Jane Schulmann, Simone Glynn, Paul Ness, J Brooks Jackson, Hua Shan | The human immunodeficiency virus-1 ge... | |
| 2011 | Xuwang Chen, Peng Zhan, Dongyue Li, Erik De Clercq, Xinyong Liu | Recent advances in DAPYs and related ... | |
| 2011 | Peng Zhan, Xuwang Chen, Dongyue Li, Zengjun Fang, Erik De Clercq, Xinyong Liu | HIV-1 NNRTIs: Structural diversity, p... | |
| 2011 | Jing Zhang, Peng Zhan, Jingde Wu, Zhongjie Li, Yan Jiang, Weiying Ge, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2011 | Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valerio Gatti, Giovanni Maga, Alberta Samuele, Christophe Pannecouque, Dominique Schols, Jan Balzarini, Ettore Novellino, Romano Silvestri | Indolylarylsulfones as HIV-1 non-nucl... | |
| 2011 | Han-Ping Li, Wei Guo, Yong-Jian Liu, Zuo-Yi Bao, Lin Li, Dao-Min Zhuang, Si-Yang Liu, Zhengqiang Wang, Xiao-Lin Wang, Jing-Yun Li | [Screening program on novel drug resi... | |
| 2011 | Claudette S Satchell, Jane A O'Halloran, Aoife G Cotter, Aaron J Peace, Eileen F O'Connor, Anthony F Tedesco, Eoin R Feeney, John S Lambert, Gerard J Sheehan, Dermot Kenny, Patrick W G Mallon | Increased Platelet Reactivity in HIV-... | |
| 2011 | Graciela Andrei, Andrea Lisco, Christophe Vanpouille, Andrea Introini, Emanuela Balestra, Joost van den Oord, Tomas Cihlar, CF Perno, Robert Snoeck, Leonid Margolis, Jan Balzarini | Topical tenofovir, a microbicide effe... | |
| 2011 | Karen A Kirby, Kamalendra Singh, Eleftherios Michailidis, Bruno Marchand, Eiichi N Kodama, Noriyuki Ashida, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | The sugar ring conformation of 4'-eth... | |
| 2011 | O Jegede, A Khodyakova, M Chernov, J Weber, L Menéndez-Arias, A Gudkov, ME Quiñones-Mateu | Identification of low-molecular weigh... | |
| 2011 | Mingyan Yu, Zhongjie Li, Shuai Liu, Erkang Fan, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2011 | Erik De Clercq | A 40-year journey in search of select... | |
| 2011 | Dante Rotili, Domenico Tarantino, Marino Artico, Maxim B Nawrozkij, Emmanuel Gonzalez-Ortega, B Clotet, Alberta Samuele, José A Esté, Giovanni Maga, Antonello Mai | Diarylpyrimidine-dihydrobenzyloxopyri... | |
| 2011 | Joseph David Bauman, Disha Patel, Edward Arnold | Fragment Screening and HIV Therapeutics. | |
| 2011 | Suhman Chung, Jennifer T Miller, Barry C Johnson, Stephen H Hughes, Stuart F J Le Grice | Mutagenesis of the human immunodefici... | |
| 2011 | Suhman Chung, Daniel M Himmel, Jian-Kang Jiang, Krzysztof Wojtak, Joseph David Bauman, Jason W Rausch, Jennifer A Wilson, John A Beutler, Craig J Thomas, Edward Arnold, Stuart F J Le Grice | Synthesis, activity, and structural a... | |
| 2011 | Anthony K Felts, Krystal Labarge, Joseph David Bauman, Dishaben V Patel, Daniel M Himmel, Edward Arnold, Michael A. Parniak, Ronald M Levy | Identification of alternative binding... | |
| 2011 | Mark A Ditzler, Debojit Bose, Nikolozi Shkriabai, Bruno Marchand, Stefan G Sarafianos, Mamuka Kvaratskhelia, Donald H Burke | Broad-spectrum aptamer inhibitors of ... | |
| 2011 | Tanyaradzwa P Ndongwe, Adeyemi O Adedeji, Eleftherios Michailidis, Yee Tsuey Ong, Atsuko Hachiya, Bruno Marchand, Emily M Ryan, Devendra K Rai, Karen A Kirby, Angela S Whatley, Donald H Burke, Marc Johnson, Shilei Ding, Yi-Min Zheng, Shan-Lu Liu, Ei-Ichi Kodama, Krista A Delviks-Frankenberry, Vinay K Pathak, Hiroyuki Mitsuya, Michael A. Parniak, Kamalendra Singh, Stefan G Sarafianos | Biochemical, inhibition and inhibitor... | |
| 2011 | María-Cruz Bonache, Alessandra Cordeiro, Ernesto Quesada, Els Vanstreels, Dirk Daelemans, María-José Camarasa, Jan Balzarini, Ana San-Félix | Selective inhibition of Human Immunod... | |
| 2011 | Dimitrios Coutsinos, Cédric F Invernizzi, Daniela D Moisi, Maureen Oliveira, Jorge L Martinez-Cajas, Bluma G Brenner, Mark A. Wainberg | A template-dependent dislocation mech... | |
| 2010 | Michael L Mitchell, Jong Chan Son, Ill Young Lee, Chong-Kyo Lee, Hae Soo Kim, Hongyan Guo, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Gene Eisenberg, Romas Geleziunas, Lianhong Xu, Choung U Kim | N1-Heterocyclic pyrimidinediones as n... | RT,All properties |
| 2010 | Hua-Poo Su, Youwei Yan, G Sridhar Prasad, Robert F Smith, Christopher L Daniels, Pravien D Abeywickrema, John C Reid, H Marie Loughran, Maria Kornienko, Sujata Sharma, Jay A Grobler, Bei Xu, Vinod Sardana, Timothy J Allison, Peter D Williams, Paul L Darke, Daria J Hazuda, Sanjeev Munshi | Structural basis for the inhibition o... | RT,RNase H,All properties |
| 2010 | Matthias Götte, Jason W Rausch, Bruno Marchand, Stefan G Sarafianos, Stuart F J Le Grice | Reverse transcriptase in motion: conf... | |
| 2010 | Hong-Tao Xu, Yudong Quan, Eugene L Asahchop, Maureen Oliveira, Daniella Moisi, Mark A. Wainberg | Comparative biochemical analysis of r... | |
| 2010 | Guido van Marle, Deirdre L Church, Kali D Nunweiler, Kris Cannon, Mark A. Wainberg, M John Gill | Higher levels of Zidovudine resistant... | |
| 2010 | Michael E Abram, Stefan G Sarafianos, Michael A. Parniak | The mutation T477A in HIV-1 reverse t... | |
| 2010 | Denis J Kertesz, Christine Brotherton-Pleiss, Minmin Yang, Zhengqiang Wang, Xianfeng Lin, Zongxing Qiu, Donald R Hirschfeld, Shelley K Gleason, Taraneh Mirzadegan, Pete W Dunten, Seth F Harris, Armando G Villaseñor, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp | Discovery of piperidin-4-yl-aminopyri... | RT,All properties |
| 2010 | Anna-Maria Monforte, Patrizia Logoteta, Laura De Luca, Nunzio Iraci, Stefania Ferro, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Novel 1,3-dihydro-benzimidazol-2-ones... | |
| 2010 | Brian D Herman, Ivan Votruba, Antonin Holy, Nicolas Sluis-Cremer, Jan Balzarini | The acyclic 2,4-diaminopyrimidine nuc... | |
| 2010 | Suhman Chung, Michaela Wendeler, Jason W Rausch, Greg L Beilhartz, Matthias Gotte, Barry R O'Keefe, Alun Bermingham, John A Beutler, Shixin Liu, Xiaowei Zhuang, Stuart F J Le Grice | Structure-activity analysis of vinylo... | |
| 2010 | Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq | 1,2,3-thiadiazole thioacetanilides. P... | |
| 2010 | Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Bluma G Brenner, Mark A. Wainberg | Factors affecting template usage in t... | |
| 2010 | Michael L Mitchell, Jong Chan Son, Hongyan Guo, Yun-A Im, Eun Jung Cho, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Doris Graupe, Gerry Rhodes, Gong-Xin He, Romas Geleziunas, Lianhong Xu, Choung U Kim | N1-Alkyl pyrimidinediones as non-nucl... | RT,All properties |
| 2010 | H Nina Kim, Jing Wang, James Hughes, Robert Coombs, Jorge Sanchez, Stewart Reid, Sinead Delany-Moretlwe, Frances Cowan, Jonathan Fuchs, Susan H Eshleman, Leila Khaki, Moira A McMahon, Robert F Siliciano, Anna Wald, Connie Celum | Effect of acyclovir on HIV-1 set poin... | |
| 2010 | Greg L Beilhartz, Matthias Götte | HIV-1 Ribonuclease H: Structure, Cata... | |
| 2010 | Viktor von Wyl, Maryam Ehteshami, Lisa M Demeter, Philippe Bürgisser, Monique Nijhuis, Jori Symons, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard | HIV-1 reverse transcriptase connectio... | |
| 2010 | Viktor von Wyl, Maryam Ehteshami, Jori Symons, Philippe Bürgisser, Monique Nijhuis, Lisa M Demeter, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard | Epidemiological and biological eviden... | |
| 2010 | Matthew W Kellinger, Kenneth A Johnson | Nucleotide-dependent conformational c... | RT,All properties |
| 2010 | Erik De Clercq | Antiretroviral drugs. | |
| 2010 | Zhao-Sen Zeng, Qiu-Qin He, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Hybrid diarylbenzopyrimidine non-nucl... | |
| 2010 | Hong-Tao Xu, Maureen Oliveira, Yudong Quan, Tamara Bar-Magen, Mark A. Wainberg | Differential impact of the HIV-1 non-... | |
| 2010 | Xiongying Tu, Kalyan Das, Qianwei Han, Joseph David Bauman, Arthur D Clark, Xiaorong Hou, Yulia Volovik Frenkel, Barbara L Gaffney, Roger A Jones, Paul L Boyer, Stephen H Hughes, Stefan G Sarafianos, Edward Arnold | Structural basis of HIV-1 resistance ... | |
| 2010 | Michael E Abram, Andrea L Ferris, Wei Shao, W Gregory Alvord, Stephen H Hughes | Nature, position, and frequency of mu... | |
| 2010 | Wujie Li, Mou Cao, Lu Pei, Xiaomei Ling, Bingchao Li, Zhenjun Yang | Study on steady-state kinetics of nuc... | RT,All properties |
| 2010 | Séverine Freisz, Guillaume Bec, Marco Radi, Philippe Wolff, Emmanuele Crespan, Lucilla Angeli, Philippe Dumas, Giovanni Maga, Maurizio Botta, Eric Ennifar | Crystal Structure of HIV-1 Reverse Tr... | RT,All properties |
| 2010 | Mia J Biondi, Greg L Beilhartz, Suzanne McCormick, Matthias Götte | N348I in HIV-1 reverse transcriptase ... | |
| 2010 | Matthew M Schuckmann, Bruno Marchand, Atsuko Hachiya, Eiichi N Kodama, Karen A Kirby, Kamalendra Singh, Stefan G Sarafianos | The N348I mutation at the connection ... | |
| 2010 | Romuald Corbau, Julie Mori, Chris Phillips, Lesley Fishburn, Alex Martin, Charles Mowbray, Wendy Panton, Caroline Smith-Burchnell, Adele Thornberry, Heather Ringrose, Thorsten Knöchel, Steve Irving, Mike Westby, Anthony Wood, Manos Perros | Lersivirine: a Non-Nucleoside Reverse... | RT,All properties |
| 2010 | Erik De Clercq | In search of a selective therapy of v... | |
| 2010 | Li-Jia Xu, Zong-Gen Peng, Hong-Shan Chen, Jie Wang, Pei-Gen Xiao | Bioactive triterpenoids from Kadsura ... | |
| 2010 | Guozhi Tang, Denis J Kertesz, Minmin Yang, Xianfeng Lin, Zhengqiang Wang, Wentao Li, Zongxing Qiu, Junli Chen, Jianghua Mei, Li Chen, Taraneh Mirzadegan, Seth F Harris, Armando G Villaseñor, Jennifer Fretland, William L Fitch, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp | Exploration of piperidine-4-yl-aminop... | |
| 2010 | John C Martin, Michael J M Hitchcock, Erik De Clercq, William H Prusoff | Early nucleoside reverse transcriptas... | |
| 2010 | Pankaj R Daga, Jinsong Duan, Robert J Doerksen | Computational model of hepatitis B vi... | |
| 2010 | Eric B Lansdon, Katherine M Brendza, Magdeleine Hung, Ruth Wang, Susmith Mukund, Debi Jin, Gabriel Birkus, Nilima Kutty, Xiaohong Liu | Crystal structures of HIV-1 reverse t... | RT,Associated condition,All properties |
| 2010 | Zhengqiang Wang, Jing Tang, Christine E Salomon, Christine D Dreis, Robert Vince | Pharmacophore and structure-activity ... | |
| 2010 | Zhao-Sen Zeng, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq | Lead optimization of diarylpyrimidine... | |
| 2010 | Yong-Hong Liang, Qiu-Qin He, Zhao-Sen Zeng, Zhi-Qian Liu, Xiao-Qing Feng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq | Synthesis and anti-HIV activity of 2-... | |
| 2010 | Martin Di Grandi, Matthew Olson, Amar S Prashad, Geraldine Bebernitz, Amara Luckay, Stanley Mullen, Yongbo Hu, Girija Krishnamurthy, Keith Pitts, John O'Connell | Small molecule inhibitors of HIV RT R... | |
| 2010 | Eric B Lansdon, Dharmaraj Samuel, Leanna Lagpacan, Katherine M Brendza, Kirsten L White, Magdeleine Hung, Xiaohong Liu, Constantine G Boojamra, Richard L Mackman, Tomas Cihlar, Adrian S Ray, Mary E McGrath, S Swaminathan | Visualizing the molecular interaction... | RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Polymerase Catalytic Residue Amino Acids,Residues Involved in Catalysis of RNase H,Incorporation of non-standard nucleotides,All properties |
| 2010 | Giovanni Maga, Marco Radi, Marie-Aline Gerard, Maurizio Botta, Eric Ennifar | HIV-1 RT Inhibitors with a Novel Mech... | |
| 2010 | Yuhua Ruan, Hui Xing, Xia Wang, Heng Tang, Zhengqiang Wang, Hongwei Liu, Bin Su, Jianjun Wu, Hanping Li, Lingjie Liao, Jinming Li, Julia Wei Wu, Yiming Shao | Virologic outcomes of first-line HAAR... | |
| 2010 | Daniel A Donahue, Richard D Sloan, Björn D Kuhl, Tamara Bar-Magen, Susan M Schader, Mark A. Wainberg | Stage-dependent inhibition of HIV-1 r... | |
| 2010 | Alberta Samuele, Emmanuele Crespan, Samanta Vitellaro, Anna-Maria Monforte, Patrizia Logoteta, Alba Chimirri, Giovanni Maga | Slow binding-tight binding interactio... | |
| 2009 | Yong-Hong Liang, Xiao-Qing Feng, Zhao-Sen Zeng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq | Design, synthesis, and SAR of naphthy... | |
| 2009 | Daniel M Himmel, Karen A Maegley, Tom A Pauly, Joseph David Bauman, Kalyan Das, Chhaya Dharia, Arthur D Clark, Kevin Ryan, Michael J Hickey, Robert A Love, Stephen H Hughes, Simon Bergqvist, Edward Arnold | Structure of HIV-1 reverse transcript... | RT,RNase H,All properties |
| 2009 | Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg | Signature nucleotide polymorphisms at... | |
| 2009 | Greg L Beilhartz, Michaela Wendeler, Noel S Baichoo, Jason W Rausch, Stuart F J Le Grice, Matthias Götte | HIV-1 reverse transcriptase can simul... | |
| 2009 | Egor P Tchesnokov, Aleksandr Obikhod, Ivana Massud, Andrea Lisco, Christophe Vanpouille, Beda Brichacek, Jan Balzarini, Christopher McGuigan, Marco Derudas, Leonid Margolis, Raymond F Schinazi, Matthias Götte | Mechanisms associated with HIV-1 resi... | |
| 2009 | Atsuko Hachiya, Kazuki Shimane, Stefan G Sarafianos, Eiichi N Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi, Shinichi Oka | Clinical relevance of substitutions i... | |
| 2009 | Marco Derudas, Davide Carta, Andrea Brancale, Christophe Vanpouille, Andrea Lisco, Leonid Margolis, Jan Balzarini, Christopher McGuigan | The application of phosphoramidate pr... | |
| 2009 | Thorsten A Kirschberg, Mini Balakrishnan, Neil H Squires, Tiffany Barnes, Katherine M Brendza, Xiaowu Chen, Eugene J Eisenberg, Weili Jin, Nilima Kutty, Stephanie Leavitt, Albert C Liclican, Qi Liu, Xiaohong Liu, John Mak, Jason K Perry, Michael Wang, William J Watkins, Eric B Lansdon | RNase H active site inhibitors of hum... | |
| 2009 | Susan P Colby-Germinario, Adan Rios, Jorge Quesada, Dallas Anderson, Allan L Goldstein, Theresa Fossum, Mark A. Wainberg | HIV inactivation by cross-linking of ... | |
| 2009 | Stefania Butini, Margherita Brindisi, Sandro Cosconati, Luciana Marinelli, Giuseppe Borrelli, Salvatore Sanna Coccone, Anna Ramunno, Giuseppe Campiani, Ettore Novellino, Samantha Zanoli, Alberta Samuele, Gianluca Giorgi, Alberto Bergamini, Michela Di Mattia, Silvana Lalli, Bruno Galletti, Sandra Gemma, Giovanni Maga | Specific targeting of highly conserve... | |
| 2009 | Anna-Maria Monforte, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Design, synthesis, and structure-acti... | |
| 2009 | Marco Radi, Giovanni Maga, Maddalena Alongi, Lucilla Angeli, Alberta Samuele, Samantha Zanoli, Luca Bellucci, Andrea Tafi, Gianni Casaluce, Gianluca Giorgi, Mercedes Armand-Ugon, Emmanuel Gonzalez, José A Esté, Mireille Baltzinger, Guillaume Bec, Philippe Dumas, Eric Ennifar, Maurizio Botta | Discovery of chiral cyclopropyl dihyd... | |
| 2009 | Erik De Clercq | A new drug combination therapy for tr... | |
| 2009 | Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2009 | Hongtao Xu, Yudong Quan, Bluma G Brenner, Tamara Bar-Magen, Maureen Oliveira, Susan M Schader, Mark A. Wainberg | Human immunodeficiency virus type 1 r... | |
| 2009 | Bo-Liang Deng, Yaofeng Zhao, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis of alkenyldiarylmethanes (A... | |
| 2009 | Franck Chiappini, Elina Teicher, Raphaël Saffroy, Brigitte Debuire, Daniel Vittecoq, Antoinette Lemoine | Relationship between polymerase gamma... | |
| 2009 | Anders Vahlne | A historical reflection on the discov... | |
| 2009 | Takuma Kimura, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Eiji Ohashi, Haruo Ohmori, Chikahide Masutani, Fumio Hanaoka, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Penicilliols A and B, novel inhibitor... | |
| 2009 | MC Puertas, MJ Buzón, A Artese, S Alcaro, L Menéndez-Arias, CF Perno, B Clotet, F Ceccherini-Silberstein, J Martinez-Picado | Effect of the human immunodeficiency ... | |
| 2009 | Yoshiyuki Mizushina, Hirohisa Motoshima, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Ken Hirano, Fumio Sugawara, Hiromi Yoshida | 3-O-methylfunicone, a selective inhib... | |
| 2009 | Alexandra Kataropoulou, Chiara Bovolenta, Amalia Belfiore, Sonia Trabatti, Anna Garbelli, Simona Porcellini, Rossella Lupo, Giovanni Maga | Mutational analysis of the HIV-1 auxi... | |
| 2009 | Paul L Boyer, B Christie Vu, Zandrea Ambrose, John G Julias, Svenja Warnecke, Chenzhong Liao, Chris Meier, Victor E Marquez, Stephen H Hughes | The nucleoside analogue D-carba T blo... | |
| 2009 | Matthew D Cullen, William C Ho, Joseph David Bauman, Kalyan Das, Edward Arnold, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Crystallographic study of a novel sub... | RT,All properties |
| 2009 | Linda L Dunn, Mary Jane McWilliams, Kalyan Das, Edward Arnold, Stephen H Hughes | Mutations in the thumb allow human im... | |
| 2009 | Xuexiang Zhang, Xueyan Jiang, Hongzhou Lu, Fang Shen, Jiangrong Wang | Dyslipidaemia and Intima-Media Thickn... | |
| 2009 | Kristina A Paris, Omar Haq, Anthony K Felts, Kalyan Das, Edward Arnold, Ronald M Levy | Conformational landscape of the human... | |
| 2009 | Dai-Shi Su, John J Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J Felock, Meiqing Lu, Ming-Tain Lai, Sinoeun Touch, Gregory Moyer, Daniel J Distefano, Jessica A Flynn, Yuexia Liang, Rosa Sanchez, Sridhar Prasad, Youwei Yan, Rebecca A Perlow-Poehnelt, Maricel Torrent, Michael D Miller, Joe P Vacca, Theresa M Williams, Neville J Anthony | Substituted tetrahydroquinolines as p... | RT,All properties |
| 2009 | Alberta Samuele, Alexandra Kataropoulou, Marco Viola, Samantha Zanoli, Giuseppe La Regina, Francesco Piscitelli, Romano Silvestri, Giovanni Maga | Non-nucleoside HIV-1 reverse transcri... | |
| 2009 | Peng Zhan, Zhongjie Li, Xinyong Liu, Erik De Clercq | Sulfanyltriazole/tetrazoles: a promis... | |
| 2009 | Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Daniela D Moisi, Maureen Oliveira, Bluma G Brenner, Mark A. Wainberg | Template usage is responsible for the... | |
| 2009 | L Menéndez-Arias | Mutation Rates and Intrinsic Fidelity... | Frameshift Error Rate,All properties |
| 2009 | Dharmesh H Mahajan, Christophe Pannecouque, Erik De Clercq, Kishor H Chikhalia | Synthesis and studies of new 2-(couma... | |
| 2009 | Hironori Nishitsuji, Takaya Hayashi, Tomosaburo Takahashi, Masashi Miyano, Mari Kannagi, Takao Masuda | Augmentation of reverse transcription... | |
| 2009 | Dan Turner, Eduardo Shahar, Eugene Katchman, Eynat Kedem, Natasha Matus, Michal Katzir, Gamal Hassoun, Shimon Pollack, Rivka Kessner, Mark A. Wainberg, Boaz Avidor | Prevalence of the K65R resistance rev... | |
| 2009 | Kazuki Izumi, Eiichi N Kodama, Kazuya Shimura, Yasuko Sakagami, Kentaro Watanabe, Saori Ito, Tsuyoshi Watabe, Yukihiro Terakawa, Hiroki Nishikawa, Stefan G Sarafianos, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka | Design of peptide-based inhibitors fo... | |
| 2009 | Peng Zhan, Xinyong Liu, Junjie Zhu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Synthesis and biological evaluation o... | |
| 2009 | Stefan G Sarafianos, Bruno Marchand, Kalyan Das, Daniel M Himmel, Michael A. Parniak, Stephen H Hughes, Edward Arnold | Structure and function of HIV-1 rever... | |
| 2009 | Young-Sam Lee, W Dexter Kennedy, Y Whitney Yin | Structural insight into processive hu... | |
| 2009 | Takeshi Naito, Kazuki Izumi, Eiichi N Kodama, Yasuko Sakagami, Keiko Kajiwara, Hiroki Nishikawa, Kentaro Watanabe, Stefan G Sarafianos, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka | SC29EK, a peptide fusion inhibitor wi... | |
| 2009 | Kalyan Das, Rajiv P Bandwar, Kirsten L White, Joy Y Feng, Stefan G Sarafianos, Steven Tuske, Xiongying Tu, Arthur D Clark, Paul L Boyer, Xiaorong Hou, Barbara L Gaffney, Roger A Jones, Michael D Miller, Stephen H Hughes, Edward Arnold | Structural basis for the role of the ... | RT,All properties |
| 2009 | Peng Zhan, Xinyong Liu, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Design strategies of novel NNRTIs to ... | |
| 2009 | Peng Zhan, Xinyong Liu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Synthesis and anti-HIV activity evalu... | |
| 2009 | Peng Zhan, Xinyong Liu, Zengjun Fang, Christophe Pannecouque, Erik De Clercq | 1,2,3-Selenadiazole thioacetanilides:... | |
| 2009 | Yudong Quan, Chen Liang, Bluma G Brenner, Mark A. Wainberg | Multidrug-resistant variants of HIV t... | |
| 2009 | Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and in vitro anti-HIV evalu... | |
| 2009 | Erik De Clercq | Anti-HIV drugs: 25 compounds approved... | |
| 2009 | Francesco Piscitelli, Antonio Coluccia, Andrea Brancale, Giuseppe La Regina, Anna Sansone, Cesare Giordano, Jan Balzarini, Giovanni Maga, Samantha Zanoli, Alberta Samuele, Roberto Cirilli, Francesco La Torre, Antonio Lavecchia, Ettore Novellino, Romano Silvestri | Indolylarylsulfones bearing natural a... | |
| 2008 | Erik De Clercq | Emerging antiviral drugs. | |
| 2008 | Jingshan Ren, Phillip P Chamberlain, Anna Stamp, Steven A Short, Kurt L Weaver, Karen R Romines, Richard J Hazen, Andrew Freeman, Robert G Ferris, C Webster Andrews, Lawrence R Boone, Joseph H Chan, David K Stammers | Structural basis for the improved dru... | RT,All properties |
| 2008 | Michaela Wendeler, Hsiu-Fang Lee, Alun Bermingham, Jennifer T Miller, Oleg Chertov, Marion K Bona, Noel S Baichoo, Maryam Ehteshami, John A Beutler, Barry R O'Keefe, Matthias Götte, Mamuka Kvaratskhelia, Stuart F J Le Grice | Vinylogous ureas as a novel class of ... | |
| 2008 | Bluma G Brenner, Michel Roger, Daniela D Moisi, Maureen Oliveira, Isabelle Hardy, Reuven Turgel, Hugues Charest, Jean-Pierre Routy, Mark A. Wainberg | Transmission networks of drug resista... | |
| 2008 | Patrick P Lestienne, François Boudsocq, Jacques E Bonnet | Initiation of DNA replication by a th... | |
| 2008 | Matthew D Cullen, York-Fong Cheung, Miles D Houslay, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Investigation of the alkenyldiarylmet... | |
| 2008 | Thorsten A Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty, Albert C Liclican, Damian J McColl, Neil H Squires, Eric B Lansdon | Triazole derivatives as non-nucleosid... | RT,All properties |
| 2008 | Jiaping Lai, Jun Wang, Zongwei Cai | Nucleoside reverse transcriptase inhi... | |
| 2008 | Mitsuki Naganuma, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | 1-deoxyrubralactone, a novel specific... | |
| 2008 | Maryam Ehteshami, Greg L Beilhartz, Brian J Scarth, Egor P Tchesnokov, Suzanne McCormick, Brian Wynhoven, P Richard Harrigan, Matthias Götte | Connection domain mutations N348I and... | |
| 2008 | Maryam Ehteshami, Brian J Scarth, Egor P Tchesnokov, Chandravanu Dash, Stuart F J Le Grice, Sabine Hallenberger, Dirk Jochmans, Matthias Götte | Mutations M184V and Y115F in HIV-1 re... | |
| 2008 | Roger G Ptak, Philippe A Gallay, Dirk Jochmans, Andrew P Halestrap, Urs T Ruegg, Luke A Pallansch, Michael D Bobardt, Marie-Pierre P De Béthune, Johan Neyts, Erik De Clercq, Jean-Maurice Dumont, Pietro Scalfaro, Kamel Besseghir, Roland M Wenger, Brigitte Rosenwirth | Inhibition of human immunodeficiency ... | |
| 2008 | Samantha Zanoli, Sandra Gemma, Stefania Butini, Margherita Brindisi, Bhupendra P Joshi, Giuseppe Campiani, Caterina Fattorusso, Marco Persico, Emmanuele Crespan, Reynel Cancio, Silvio Spadari, Ulrich Hübscher, Giovanni Maga | Selective targeting of the HIV-1 reve... | |
| 2008 | Peng Zhan, Xinyong Liu, Yuan Cao, Yan Wang, Christophe Pannecouque, Erik De Clercq | 1,2,3-Thiadiazole thioacetanilides as... | |
| 2008 | Samir Abdurahman, Akos Végvári, Masoud Youssefi, Michael Levi, Stefan Höglund, Elin Andersson, Peter Horal, Bo Svennerholm, Jan Balzarini, Anders Vahlne | Activity of the small modified amino ... | |
| 2008 | Atsuko Hachiya, Eiichi N Kodama, Stefan G Sarafianos, Matthew M Schuckmann, Yasuko Sakagami, Masao Matsuoka, Masafumi Takiguchi, Hiroyuki Gatanaga, Shinichi Oka | Amino acid mutation N348I in the conn... | |
| 2008 | Anna-Maria Monforte, Angela Rao, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Maria Letizia Barreca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Novel N1-substituted 1,3-dihydro-2H-b... | |
| 2008 | Joseph David Bauman, Kalyan Das, William C Ho, Mukta Baweja, Daniel M Himmel, Arthur D Clark, Deena A Oren, Paul L Boyer, Stephen H Hughes, Aaron J Shatkin, Edward Arnold | Crystal engineering of HIV-1 reverse ... | RT,All properties |
| 2008 | Zhijian Zhao, Scott E Wolkenberg, Philip E J Sanderson, Meiqing Lu, Vandna Munshi, Gregory Moyer, Meizhen Feng, Anthony V Carella, Linda T Ecto, Lori J Gabryelski, Ming-Tain Lai, Sridar G Prasad, Youwei Yan, Georgia B McGaughey, Michael D Miller, Craig W Lindsley, George D Hartman, Joseph P Vacca, Theresa M Williams | Novel indole-3-sulfonamides as potent... | RT,All properties |
| 2008 | Takuma Kimura, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Novel azaphilones, kasanosins A and B... | |
| 2008 | Chandravanu Dash, Brian J Scarth, Christopher Badorrek, Matthias Götte, Stuart F J Le Grice | Examining the ribonuclease H primer g... | |
| 2008 | Zachary K Sweeney, Seth F Harris, Seth F Arora, Hassan Javanbakht, Yingqian Li, Jennifer Fretland, James P Davidson, J Roland Billedeau, Shelley K Gleason, Donald R Hirschfeld, Joshua J Kennedy-Smith, Taraneh Mirzadegan, Ralf Roetz, Mark Smith, Sarah Sperry, Judy M Suh, Jeffrey Wu, Stan Tsing, Armando G Villaseñor, Amber Paul, Guoping Su, Gabrielle M Heilek, Julie Qi Hang, Amy S Zhou, Jesper A Jernelius, Fang-Jie Zhang, Klaus Klumpp | Design of annulated pyrazoles as inhi... | RT,All properties |
| 2008 | Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Marco Ponassi, Torsten Unge, Martino Bolognesi | Crystal structures of HIV-1 reverse t... | RT,All properties |
| 2008 | Thomas J Tucker, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, John C Reid, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan | Discovery of 3-{5-[(6-amino-1H-pyrazo... | RT,All properties |
| 2008 | Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2008 | Andrea Lisco, Christophe Vanpouille, Egor P Tchesnokov, Jean-Charles Grivel, Angélique Biancotto, Beda Brichacek, Julie Elliott, Emilie Fromentin, Robin Shattock, Peter Anton, Robert Gorelick, Jan Balzarini, Christopher McGuigan, Marco Derudas, Matthias Götte, Raymond F Schinazi, Leonid Margolis | Acyclovir is activated into a HIV-1 r... | RT,All properties |
| 2008 | Kalyan Das, Joseph David Bauman, Arthur D Clark, Yulia Volovik Frenkel, Paul J Lewi, Aaron J Shatkin, Stephen H Hughes, Edward Arnold | High-resolution structures of HIV-1 r... | RT,All properties |
| 2008 | Atsushi Kawamoto, Eiichi N Kodama, Stefan G Sarafianos, Yasuko Sakagami, Satoru Kohgo, Kenji Kitano, Noriyuki Ashida, Yuko Iwai, Hiroyuki Hayakawa, Hirotomo Nakata, Hiroyuki Mitsuya, Edward Arnold, Masao Matsuoka | 2'-deoxy-4'-C-ethynyl-2-halo-adenosin... | |
| 2008 | Julie Lemay, Priscilla Maidou-Peindara, Reynel Cancio, Eric Ennifar, Gaël Coadou, Giovanni Maga, Jean-Christophe Rain, Richard Benarous, Lang Xia Liu | AKAP149 binds to HIV-1 reverse transc... | |
| 2008 | Alberta Samuele, Marcella Facchini, Dante Rotili, Antonello Mai, Marino Artico, Mercedes Armand-Ugón, José A Esté, Giovanni Maga | Substrate-induced stable enzyme-inhib... | |
| 2008 | Marco Radi, Chiara Falciani, Lorenzo Contemori, Elena Petricci, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Montserrat Terrazas, Marinunzia Castria, Andrea Togninelli, José A Esté, Imma Clotet-Codina, Mercedes Armand-Ugón, Maurizio Botta | A multidisciplinary approach for the ... | |
| 2008 | Bechan Sharma, Emmanuele Crespan, Giuseppe Villani, Giovanni Maga | The balance between the rates of inco... | |
| 2008 | Jangsuk Oh, Mary Jane McWilliams, John G Julias, Stephen H Hughes | Mutations in the U5 region adjacent t... | |
| 2008 | Lu Gao, Mark Nils Hanson, Mini Balakrishnan, Paul L Boyer, Bernard P Roques, Stephen H Hughes, Baek Kim, Robert A Bambara | Apparent defects in processive DNA sy... | |
| 2008 | Krista A Delviks-Frankenberry, Galina N Nikolenko, Paul L Boyer, Stephen H Hughes, John M Coffin, Abhay Jere, Vinay K Pathak | HIV-1 reverse transcriptase connectio... | |
| 2008 | Michel L Ntemgwa, Thomas D'Aquin Toni, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Maureen Oliveira, Mark A. Wainberg | Near full-length genomic analysis of ... | |
| 2008 | Zachary K Sweeney, James P Dunn, Yingqian Li, Gabrielle M Heilek, Pete W Dunten, Todd R Elworthy, Xiaochun Han, Seth F Harris, Donald R Hirschfeld, J Heather Hogg, Walter Huber, Ann C Kaiser, Denis J Kertesz, Woongki Kim, Taraneh Mirzadegan, Michael G Roepel, Y David Saito, Tania M P C Silva, Steven Swallow, Jahari L Tracy, Armando Villasenor, Harit Vora, Amy S Zhou, Klaus Klumpp | Discovery and optimization of pyridaz... | RT,All properties |
| 2008 | Maryam Ehteshami, Matthias Götte | Effects of mutations in the connectio... | |
| 2008 | Zhengqiang Wang, Robert Vince | Design and synthesis of dual inhibito... | |
| 2008 | Fang Yu, Xinyong Liu, Peng Zhan, Erik De Clercq | Recent advances in the research of HI... | |
| 2008 | Zhengqiang Wang, Robert Vince | Synthesis of pyrimidine and quinolone... | |
| 2008 | Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte | Delayed chain termination protects th... | |
| 2008 | Thomas J Tucker, Sandeep Saggar, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan | The design and synthesis of diaryl et... | RT,All properties |
| 2008 | Yueping Wang, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse-transcri... | |
| 2008 | Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and biological evaluation o... | |
| 2008 | Chong Fang, Joseph David Bauman, Kalyan Das, Amanda Remorino, Edward Arnold, Robin M Hochstrasser | Two-dimensional infrared spectra reve... | |
| 2008 | Tatiana Ilina, Michael A. Parniak | Inhibitors of HIV-1 reverse transcrip... | |
| 2008 | Scott J Garforth, Michael A. Parniak, Vinayaka R Prasad | Utilization of a deoxynucleoside diph... | |
| 2008 | Yongcheng Song, Julian M W Chan, Zev Tovian, Aaron Secrest, Eva Nagy, Kilannin Krysiak, Kyle Bergan, Michael A. Parniak, Eric Oldfield | Bisphosphonate inhibitors of ATP-medi... | |
| 2008 | Guangwei Yang, Jianhong Wang, Yao Cheng, Ginger E Dutschman, Hiromichi Tanaka, Masanori Baba, Yung-Chi Cheng | Mechanism of inhibition of human immu... | |
| 2008 | Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Design and synthesis of 2-(2,6-dibrom... | |
| 2008 | Ravindra K Rawal, Rajkamal Tripathi, Smitha Kulkarni, R Paranjape, S B Katti, Christophe Pannecouque, Erik De Clercq | 2-(2,6-Dihalo-phenyl)-3-heteroaryl-2-... | |
| 2007 | Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna-Maria Monforte, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Alba Chimirri | Discovery of novel benzimidazolones a... | |
| 2007 | P Richard Harrigan, Theresa Mo, Jennifer Hirsch, Zabrina L Brumme, Paula McKenna, Lee Bacheler | A 21-base pair insertion/duplication ... | |
| 2007 | Tokumi Maruyama, Yosuke Demizu, Shigetada Kozai, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq | Antiviral activity of 3-(3,5-dimethyl... | |
| 2007 | Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J Low, Peter K Cheung, P Richard Harrigan, Thomas Lengauer, Francisco S Domingues | Structural descriptors of gp120 V3 lo... | |
| 2007 | Shinji Kamisuki, Chisato Ishimaru, Kadohiro Onoda, Isoko Kuriyama, Noriko Ida, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Nodulisporol and Nodulisporone, novel... | |
| 2007 | Guangwei Yang, Ginger E Dutschman, Chuan-Jen Wang, Hiromichi Tanaka, Masanori Baba, Karen S Anderson, Yung-Chi Cheng | Highly selective action of triphospha... | |
| 2007 | Sanjeewa Dharmasena, Zita Pongracz, Edward Arnold, Stefan G Sarafianos, Michael A. Parniak | 3'-Azido-3'-deoxythymidine-(5')-tetra... | RT,All properties |
| 2007 | Clara E Cases-González, Sandra Franco, Miguel Angel Martínez, L Menéndez-Arias | Mutational patterns associated with t... | |
| 2007 | Kalyan Das, Stefan G Sarafianos, Arthur D Clark, Paul L Boyer, Stephen H Hughes, Edward Arnold | Crystal structures of clinically rele... | |
| 2007 | Wei-Hao Liao, Kuo-Jung Huang, Yu-Fen Chang, Shiu-Mei Wang, Ying-Tzu Tseng, Chien-Cheng Chiang, Jaang-Jiun Wang, Chin-Tien Wang | Incorporation of human immunodeficien... | |
| 2007 | Chanson J Brumme, P Richard Harrigan, Emma C Preston, Winnie W Y Dong, Brian Wynhoven, Carol Murphy, Julio S G Montaner | Transmission of drug-resistant HIV-1 ... | |
| 2007 | Jan Balzarini, Barbara Orzeszko, Jan K Maurin, Andrzej Orzeszko | Synthesis and anti-HIV studies of 2-a... | |
| 2007 | Sonia de Castro, Graziela Andrei, Robert Snoeck, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez | Novel non-nucleoside human cytomegalo... | |
| 2007 | Elizabeth J Phillips, Sonia Gutiérrez, Natalie Jahnke, Benita Yip, Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, Julio S G Montaner | Determinants of nevirapine hypersensi... | |
| 2007 | Kristel Van Laethem, Christophe Pannecouque, Anne-Mieke Vandamme | Mutations at 65 and 70 within the con... | |
| 2007 | Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh, Eiichi N Kodama, Guangwei Yang, Christopher M Bailey, Satoru Kohgo, Hiroyuki Hayakawa, Masao Matsuoka, Karen S Anderson, Yung-Chi Cheng, Hiroyuki Mitsuya | Activity against human immunodeficien... | |
| 2007 | Paul L Boyer, Carolyn R Stenbak, David Hoberman, Maxine L Linial, Stephen H Hughes | In vitro fidelity of the prototype pr... | Full length or truncated,Frameshift Error Rate,Nucleotide Substitution Rate,Overall Error Rate,All properties |
| 2007 | Matthew D Cullen, Bo-Liang Deng, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis and biological evaluation o... | |
| 2007 | Hikaru Yamanaka, Hiroyuki Gatanaga, Pope Kosalaraksa, Saori Matsuoka-Aizawa, Tomonori Takahashi, Seisuke Kimura, Shinichi Oka | Novel mutation of human DNA polymeras... | |
| 2007 | Celia K S Chui, Zabrina L Brumme, Chanson J Brumme, Benita Yip, Elizabeth J Phillips, Julio S G Montaner, P Richard Harrigan | A simple screening approach to reduce... | |
| 2007 | Dirk Daelemans, Richard Lu, Erik De Clercq, Alan Engelman | Characterization of a replication-com... | |
| 2007 | Tobias Sing, Andrew J Low, Niko Beerenwinkel, Oliver Sander, Peter K Cheung, Francisco S Domingues, Joachim Büch, Martin Däumer, Rolf Kaiser, Thomas Lengauer, P Richard Harrigan | Predicting HIV coreceptor usage on th... | |
| 2007 | Giovanni Maga, Marco Radi, Samantha Zanoli, Fabrizio Manetti, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Chiara Falciani, Montserrat Terrazas, Jaume Vilarrasa, Maurizio Botta | Discovery of non-nucleoside inhibitor... | |
| 2007 | Dirk Eggink, Marleen C D G Huigen, Charles A B Boucher, Matthias Götte, Monique Nijhuis | Insertions in the beta3-beta4 loop of... | |
| 2007 | Zabrina L Brumme, Chanson J Brumme, Celia K S Chui, Theresa Mo, Brian Wynhoven, Conan K Woods, Bethany M Henrick, Robert S Hogg, Julio S G Montaner, P Richard Harrigan | Effects of human leukocyte antigen cl... | |
| 2007 | Andrew J Low, Winnie W Y Dong, Dennison Chan, Tobias Sing, Ronald Swanstrom, Mark Jensen, Satish Pillai, Benjamin Good, P Richard Harrigan | Current V3 genotyping algorithms are ... | |
| 2007 | Giuseppe La Regina, Antonio Coluccia, Francesco Piscitelli, Alberto Bergamini, Anna Sinistro, Antonella Cavazza, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Ettore Novellino, Marino Artico, Romano Silvestri | Indolyl aryl sulfones as HIV-1 non-nu... | |
| 2007 | Michael G Thomas, Giovanni Maga, Jean-François Mouscadet, Nicola M Howarth | Investigation of novel lipid-function... | |
| 2007 | Lingjie Liao, Hui Xing, Xincang Li, Yuhua Ruan, Yongqing Zhang, Guangming Qin, Yiming Shao | Genotypic analysis of the protease an... | |
| 2007 | L W Y Tam, Robert S Hogg, Benita Yip, J S G Montaner, P Richard Harrigan, Chanson J Brumme | Performance of a World Health Organiz... | |
| 2007 | Fernando A Frankel, Dimitrios Coutsinos, Hongtao Xu, Mark A. Wainberg | Kinetics of inhibition of HIV type 1 ... | |
| 2007 | Alok Mulky, B Christie Vu, Joan A Conway, Stephen H Hughes, John C Kappes | Analysis of amino acids in the beta7-... | |
| 2007 | M R Loutfy, J M Raboud, J S G Montaner, T Antoniou, Brian Wynhoven, F Smaill, D Rouleau, J Gill, W Schlech, Zabrina L Brumme, Theresa Mo, K Gough, A Rachlis, P Richard Harrigan, S L Walmsley | Assay of HIV gp41 amino acid sequence... | |
| 2007 | Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, David Moore, Benita Yip, Evan Wood, Julio S G Montaner | Continued improvement in survival amo... | |
| 2007 | Lei Ji, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV-1 activity eva... | |
| 2007 | J Scott Daniels, Robert Espina, Kevin Cao, Haodan Yuan, Jianrong Lin, Sharon Diamond, Barry Johnson, James Rodgers, Shimoga Prakash, Steve Unger, David Christ, Gerald Miwa, Liang-Shang Gan, Abdul Mutlib | Species-specific, P450- and sulfotran... | |
| 2007 | George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Matthias Gotte, Janice D Pata, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice | Investigating the "steric gate" of hu... | |
| 2007 | Qianwei Han, Stefan G Sarafianos, Edward Arnold, Michael A. Parniak, Barbara L Gaffney, Roger A Jones | Synthesis of AZTpSpCX2ppSA and AZTpSp... | |
| 2007 | Stefania Paolucci, Fausto Baldanti, Giulia Campanini, Reynel Cancio, Amalia Belfiore, Giovanni Maga, Giuseppe Gerna | NNRTI-selected mutations at codon 190... | |
| 2007 | Matthias Götte | Should we include connection domain m... | |
| 2007 | Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, Joseph H Chan, Jörg-Peter Kleim, David K Stammers | Relationship of potency and resilienc... | RT,All properties |
| 2007 | Lei Ji, Fen-Er Chen, Bin Xie, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV activity evalu... | |
| 2007 | Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Synthesis and evaluation of 2-(2,6-di... | |
| 2007 | Erik De Clercq | Anti-HIV drugs. | |
| 2007 | Bruno Marchand, Kirsten L White, John K Ly, Nicolas A Margot, Ruth Wang, Martin J McDermott, Michael D Miller, Matthias Götte | Effects of the translocation status o... | |
| 2007 | Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia K S Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P Richard Harrigan | Evidence of differential HLA class I-... | |
| 2007 | William C Drosopoulos, Vinayaka R Prasad | The active site residue Valine 867 in... | |
| 2007 | Marshall L Morningstar, Thomas Roth, David W Farnsworth, Marilyn B Kroeger Smith, Karen M Watson, Robert W Buckheit, Kalyan Das, Weiming Zhang, Edward Arnold, John G Julias, Stephen H Hughes, Christopher J Michejda | Synthesis, biological activity, and c... | |
| 2007 | Bruno Marchand, Egor P Tchesnokov, Matthias Götte | The pyrophosphate analogue foscarnet ... | RT,All properties |
| 2007 | Christian Castro, Eric D Smidansky, Kenneth R Maksimchuk, Jamie J Arnold, Victoria S Korneeva, Matthias Götte, William H Konigsberg, Craig E Cameron | Two proton transfers in the transitio... | |
| 2007 | Naoko Iwata, Hiroaki Yoshida, Minoru Tobiume, Fumiko Ono, Takuya Shimazaki, Tetsutaro Sata, Noriko Nakajima | Simian fetal brain progenitor cells f... | |
| 2007 | Zhengqiang Wang, Eric M Bennett, Daniel J Wilson, Christine E Salomon, Robert Vince | Rationally designed dual inhibitors o... | |
| 2007 | Yazan El Safadi, Valérie Vivet-Boudou, Roland Marquet | HIV-1 reverse transcriptase inhibitors. | RT,All properties |
| 2007 | Jingde Wu, Xinyong Liu, Xianchao Cheng, Yuan Cao, Defeng Wang, Zhongjie Li, Wenfang Xu, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq | Synthesis of novel derivatives of 4-a... | |
| 2007 | Ravindra K Rawal, Raj Kamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Synthesis and biological evaluation o... | |
| 2007 | Katharina Skrabal, Andrew J Low, Winnie W Y Dong, Tobias Sing, Peter K Cheung, Fabrizio Mammano, P Richard Harrigan | Determining human immunodeficiency vi... | |
| 2007 | Scott J Garforth, Tae Woo Kim, Michael A. Parniak, Eric T Kool, Vinayaka R Prasad | Site-directed mutagenesis in the fing... | |
| 2007 | Kassim F Adebambo, Samantha Zanoli, Michael G Thomas, Reynel Cancio, Nicola M Howarth, Giovanni Maga | N2-benzyloxycarbonylguan-9-yl acetic ... | |
| 2007 | Fernando A Frankel, Cédric F Invernizzi, Maureen Oliveira, Mark A. Wainberg | Diminished efficiency of HIV-1 revers... | |
| 2007 | Reynel Cancio, Antonello Mai, Dante Rotili, Marino Artico, Gianluca Sbardella, Imma Clotet-Codina, José A Esté, Emmanuele Crespan, Samantha Zanoli, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Slow-, tight-binding HIV-1 reverse tr... | |
| 2007 | Galina N Nikolenko, Krista A Delviks-Frankenberry, Sarah Palmer, Frank Maldarelli, Matthew J Fivash, John M Coffin, Vinay K Pathak | Mutations in the connection domain of... | |
| 2007 | Soo-Huey Yap, Chih-Wei Sheen, Jonathan Fahey, Mark Zanin, David Tyssen, Viviane Dias Lima, Brian Wynhoven, Michael Kuiper, Nicolas Sluis-Cremer, P Richard Harrigan, Gilda Tachedjian | N348I in the connection domain of HIV... | RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Storage requirements,RNase H,All properties |
| 2007 | Jianbin Wang, H X Wang, T B Ng | A peptide with HIV-1 reverse transcri... | |
| 2007 | Jianing Wang, Yunho Jin, Kimberly L Rapp, Raymond F Schinazi, Chung K Chu | D- and L-2',3'-didehydro-2',3'-dideox... | |
| 2007 | Marleen C D G Huigen, Loek de Graaf, Dirk Eggink, Rob Schuurman, Viktor Müller, Anna Stamp, David K Stammers, Charles A B Boucher, Monique Nijhuis | Evolution of a novel 5-amino-acid ins... | |
| 2007 | Silvia Bertagnolio, Luis Soto-Ramirez, Richard Pilon, Roberto Rodriguez, Monica Viveros, Luis Fuentes, P Richard Harrigan, Theresa Mo, Don Sutherland, Paul Sandstrom | HIV-1 drug resistance surveillance us... | |
| 2007 | Paul L Boyer, John G Julias, Zandrea Ambrose, Maqbool A Siddiqui, Victor E Marquez, Stephen H Hughes | The nucleoside analogs 4'C-methyl thy... | |
| 2007 | Adrian S Ray, Joy Y Feng, Eisuke Murakami, Chung K Chu, Raymond F Schinazi, Karen S Anderson | Interaction of 2'-deoxyguanosine trip... | |
| 2007 | Takeshi Sakamoto, Matthew D Cullen, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis and anti-HIV activity of ne... | |
| 2007 | Krista A Delviks-Frankenberry, Galina N Nikolenko, Rebekah Barr, Vinay K Pathak | Mutations in human immunodeficiency v... | |
| 2007 | Matthias Götte | Mechanisms of resistance associated w... | |
| 2006 | Antonio Lavecchia, Roberta Costi, Marino Artico, Gaetano Miele, Ettore Novellino, Alberto Bergamini, Emmanuele Crespan, Giovanni Maga, Roberto Di Santo | Arylthiopyrrole (AThP) derivatives as... | |
| 2006 | Varuni K Jamburuthugoda, Pauline Chugh, Baek Kim | Modification of human immunodeficienc... | |
| 2006 | Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Combining mutations in HIV-1 reverse ... | |
| 2006 | Lei Ji, Fen-Er Chen, Xiao-Qing Feng, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2006 | Christine E Koval, Carrie Dykes, Jiong Wang, Lisa M Demeter | Relative replication fitness of efavi... | |
| 2006 | Monica E Hamburgh, Kenneth A Curr, Melissa Monaghan, Vasudev R Rao, Snehlata Tripathi, Bradley D Preston, Stefan G Sarafianos, Edward Arnold, Thomas Darden, Vinayaka R Prasad | Structural determinants of slippage-m... | |
| 2006 | Klaus Klumpp, Tara Mirzadegan | Recent progress in the design of smal... | |
| 2006 | Nicolas Sluis-Cremer, Noureddine Hamamouch, Ana San Félix, Sonsoles Velazquez, Jan Balzarini, María-José Camarasa | Structure-activity relationships of [... | |
| 2006 | Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong | Novel nonnucleoside inhibitors that s... | |
| 2006 | Tokumi Maruyama, Shigetada Kozai, Yosuke Demizu, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq | Synthesis and anti-HIV-1 and anti-HCM... | |
| 2006 | Jiong Wang, Carrie Dykes, R A Domaoal, Christine E Koval, R A Bambara, Lisa M Demeter | The HIV-1 reverse transcriptase mutan... | |
| 2006 | Matthias Götte | Effects of nucleotides and nucleotide... | RT,All properties |
| 2006 | Gabriella De Martino, Giuseppe La Regina, Rino Ragno, Antonio Coluccia, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri | Indolyl aryl sulphones as HIV-1 non-n... | |
| 2006 | Sarit Aviel-Ronen, Chang Qi Zhu, Bradley P Coe, Ni Liu, Spencer K Watson, Wan L Lam, Ming Sound Tsao | Large fragment Bst DNA polymerase for... | |
| 2006 | Paul L Boyer, Stefan G Sarafianos, Patrick K Clark, Edward Arnold, Stephen H Hughes | Why do HIV-1 and HIV-2 use different ... | |
| 2006 | Zandrea Ambrose, John G Julias, Paul L Boyer, Vineet N Kewalramani, Stephen H Hughes | The level of reverse transcriptase (R... | |
| 2006 | Roberto Di Santo, Roberta Costi, Marino Artico, Rino Ragno, Antonio Lavecchia, Ettore Novellino, Enrico Gavuzzo, Francesco La Torre, Roberto Cirilli, Reynel Cancio, Giovanni Maga | Design, synthesis, biological evaluat... | |
| 2006 | Valentina Svicher, Tobias Sing, Maria Mercedes Santoro, Federica Forbici, Fátima Rodríguez-Barrios, Ada Bertoli, Niko Beerenwinkel, Maria Concetta Bellocchi, Federigo Gago, Antonella d'Arminio Monforte, Andrea Antinori, Thomas Lengauer, F Ceccherini-Silberstein, CF Perno | Involvement of novel human immunodefi... | |
| 2006 | Hiroshi Ohrui, Satoru Kohgo, Hiroyuki Hayakawa, Eiichi N Kodama, Masao Matsuoka, Tomohiro Nakata, Hiroyuki Mitsuya | 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosi... | RT,All properties |
| 2006 | Carrie Dykes, Jiong Wang, Xia Jin, Vicente Planelles, Dong Sung An, Amanda Tallo, Yangxin Huang, Hulin Wu, Lisa M Demeter | Evaluation of a multiple-cycle, recom... | |
| 2006 | Carlos Cruchaga, Elena Ansó, Ana Rouzaut, Juan J Martínez-Irujo | Selective excision of chain-terminati... | |
| 2006 | Bo-Liang Deng, Matthew D Cullen, Zhigang Zhou, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman | Synthesis and anti-HIV activity of ne... | |
| 2006 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, Federico Gago | Dimerization inhibitors of HIV-1 reve... | |
| 2006 | Frank Goebel, Alexy Yakovlev, Anton L Pozniak, Elena Vinogradova, Griet Boogaerts, Richard Hoetelmans, Marie-Pierre P De Béthune, Monika Peeters, Brian Woodfall | Short-term antiviral activity of TMC2... | |
| 2006 | Jingshan Ren, Charles E Nichols, Anna Stamp, Phillip P Chamberlain, Robert G Ferris, Kurt L Weaver, Steven A Short, David K Stammers | Structural insights into mechanisms o... | |
| 2006 | Roberto Di Santo, Roberta Costi, Marino Artico, Gaetano Miele, Antonio Lavecchia, Ettore Novellino, Alberto Bergamini, Reynel Cancio, Giovanni Maga | Arylthiopyrrole (AThP) derivatives as... | |
| 2006 | Dirk Jochmans, Jérôme Deval, Bart Kesteleyn, Herwig Van Marck, Eva Bettens, Inky De Baere, Pascale Dehertogh, Tania Ivens, Marcia Van Ginderen, Bertrand Van Schoubroeck, Maryam Ehteshami, Piet Wigerinck, Matthias Götte, Kurt Hertogs | Indolopyridones inhibit human immunod... | RT,All properties |
| 2006 | CF Perno, Valentina Svicher, Dominique Schols, Michela Pollicita, Jan Balzarini, Stefano Aquaro | Therapeutic strategies towards HIV-1 ... | |
| 2006 | Kirsten L White, James M Chen, Joy Y Feng, Nicolas A Margot, John K Ly, Adrian S Ray, Holly L Macarthur, Martin J McDermott, S Swaminathan, Michael D Miller | The K65R reverse transcriptase mutati... | |
| 2006 | N Machouf, R Thomas, V K Nguyen, B Trottier, M R Boulassel, Mark A. Wainberg, Jean-Pierre Routy | Effects of drug resistance on viral l... | |
| 2006 | Enzo Tramontano | HIV-1 RNase H: recent progress in an ... | |
| 2006 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, María-Cruz Bonache, Sonia de Castro | TSAO derivatives, inhibitors of HIV-1... | |
| 2006 | Daniel M Himmel, Stefan G Sarafianos, Sanjeewa Dharmasena, Mohammed M Hossain, Kessler McCoy-Simandle, Tatiana Ilina, Arthur D Clark, Jennifer L Knight, John G Julias, Patrick K Clark, Karsten Krogh-Jespersen, Ronald M Levy, Stephen H Hughes, Michael A. Parniak, Edward Arnold | HIV-1 reverse transcriptase structure... | RT,RNase H,All properties |
| 2006 | Najim A Al-Masoudi, Yaseen A Al-Soud, Aris Kalogerakis, Christophe Pannecouque, Erik De Clercq | Nitroimidazoles, part 2: Synthesis, a... | |
| 2005 | Daniel Summerer, Andreas Marx | 4'C-ethynyl-thymidine acts as a chain... | |
| 2005 | Hong Zang, Thomas M Harris, F Peter Guengerich | Kinetics of nucleotide incorporation ... | |
| 2005 | Hong Zang, Thomas M Harris, F Peter Guengerich | Kinetics of nucleotide incorporation ... | |
| 2005 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez | TSAO derivatives the first non-peptid... | |
| 2005 | Kirsten L White, Nicolas A Margot, John K Ly, James M Chen, Adrian S Ray, Martina Pavelko, Ruth Wang, Martin J McDermott, S Swaminathan, Michael D Miller | A combination of decreased NRTI incor... | |
| 2005 | Myriam Witvrouw, Valery Fikkert, Anke Hantson, Christophe Pannecouque, Barry R O'keefe, James McMahon, Leonidas Stamatatos, Erik De Clercq, Anders Bolmstedt | Resistance of human immunodeficiency ... | |
| 2005 | Scott R Budihas, Inna Gorshkova, Sergei A Gaidamakov, Antony Wamiru, Marion K Bona, Michael A. Parniak, Robert J Crouch, James B McMahon, John A Beutler, Stuart F J Le Grice | Selective inhibition of HIV-1 reverse... | |
| 2005 | Micha Nethe, Ben Berkhout, Antoinette C van der Kuyl | Retroviral superinfection resistance. | |
| 2005 | F Ceccherini-Silberstein, Federico Gago, Maria Mercedes Santoro, Caterina Gori, Valentina Svicher, Fátima Rodríguez-Barrios, Roberta d'Arrigo, Massimo Ciccozzi, Ada Bertoli, Antonella d'Arminio Monforte, Jan Balzarini, Andrea Antinori, CF Perno | High sequence conservation of human i... | |
| 2005 | Dan Turner, Bluma G Brenner, Daniela Mosis, Chen Liang, Mark A. Wainberg | Substitutions in the reverse transcri... | |
| 2005 | Luis R Miranda, Matthias Götte, Fei Liang, Daniel R Kuritzkes | The L74V mutation in human immunodefi... | |
| 2005 | Lia van der Hoek, Nicole Back, Maarten F Jebbink, Anthony de Ronde, Margreet Bakker, Suzanne Jurriaans, Peter Reiss, Neil Parkin, Ben Berkhout | Increased multinucleoside drug resist... | |
| 2005 | Ben Berkhout, Anthony de Ronde, Lia van der Hoek | Aggressive HIV-1? | |
| 2005 | Ronald B Geskus, Laurence Meyer, Jean-Baptiste Hubert, Hanneke Schuitemaker, Ben Berkhout, Christine Rouzioux, Ioannis D Theodorou, Jean-François Delfraissy, Maria Prins, Roel A Coutinho | Causal pathways of the effects of age... | |
| 2005 | Daniel M Himmel, Kalyan Das, Arthur D Clark, Stephen H Hughes, Abdellah Benjahad, Said Oumouch, Jérôme Guillemont, Sophie Coupa, Alain Poncelet, Imre Csoka, Christophe Meyer, Koen Andries, Chi Hung Nguyen, David S Grierson, Edward Arnold | Crystal structures for HIV-1 reverse ... | RT,Associated condition,All properties |
| 2005 | Jan Balzarini, Miguel Stevens, Erik De Clercq, Dominique Schols, Christophe Pannecouque | Pyridine N-oxide derivatives: unusual... | |
| 2005 | Jan Balzarini, Kristel Van Laethem, Sigrid Hatse, Matheus Froeyen, Els Van Damme, Anders Bolmstedt, Willy Peumans, Erik De Clercq, Dominique Schols | Marked depletion of glycosylation sit... | |
| 2005 | Jan Balzarini, Joeri Auwerx, Fátima Rodríguez-Barrios, Allel Chedad, Viktor Farkas, F Ceccherini-Silberstein, Carlos García-Aparicio, Sonsoles Velázquez, Erik De Clercq, CF Perno, María-José Camarasa, Federico Gago | The amino acid Asn136 in HIV-1 revers... | |
| 2005 | Joeri Auwerx, Joke Van Nieuwenhove, Fátima Rodríguez-Barrios, Sonia de Castro, Sonsoles Velázquez, F Ceccherini-Silberstein, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini | The N137 and P140 amino acids in the ... | |
| 2005 | Guang-Fu Sun, Xu-Xiang Chen, Fen-Er Chen, Yue-Ping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse-transcrip... | |
| 2005 | Michael E Abram, Michael A. Parniak | Virion instability of human immunodef... | |
| 2005 | Ariel Roldan, Otis U Warren, Rodney S Russell, Chen Liang, Mark A. Wainberg | A HIV-1 minimal gag protein is superi... | |
| 2005 | Melaku Adal, Workenesh Ayele, Dawit Wolday, Kifle Dagne, Tsehaynesh Messele, Tesfaye Tilahun, Ben Berkhout, Shlomo Mayaan, Georgios Pollakis, Wendelien Dorigo-Zetsma | Evidence of genetic variability of hu... | |
| 2005 | Michael E Ignatov, Anthony J Berdis, Stuart F J Le Grice, Mary D Barkley | Attenuation of DNA replication by HIV... | |
| 2005 | Erik De Clercq | Emerging anti-HIV drugs. | |
| 2005 | Ariel Fernández, Dan S Tawfik, Ben Berkhout, Rogier W Sanders, Andrzej Kloczkowski, Taner Sen, Bob Jernigan | Protein promiscuity: drug resistance ... | |
| 2005 | Fátima Rodríguez-Barrios, Jan Balzarini, Federico Gago | The molecular basis of resilience to ... | |
| 2005 | Joeri Auwerx, Fátima Rodríguez-Barrios, F Ceccherini-Silberstein, Ana San-Félix, Sonsoles Velázquez, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini | The role of Thr139 in the human immun... | |
| 2005 | Albert Nguyen Van Nhien, Cyrille Tomassi, Christophe Len, José Luis Marco-Contelles, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Denis Postel | First synthesis and evaluation of the... | |
| 2005 | Guang-Fu Sun, Yun-Yan Kuang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Non-nucleoside HIV reverse transcript... | |
| 2005 | Darwin J Operario, Holly M Reynolds, Baek Kim | Comparison of DNA polymerase activiti... | Molecular Weight,Overall Error Rate,All properties |
| 2005 | Pia S Kivelä, Anneke Krol, Mika O Salminen, Ronald B Geskus, Jukka I Suni, Veli-Jukka Anttila, Kirsi Liitsola, Veera Zetterberg, Frank Miedema, Ben Berkhout, Roel A Coutinho, Matti A Ristola | High plasma HIV load in the CRF01-AE ... | |
| 2005 | Jan Heeres, Marc R De Jonge, Lucien M H Koymans, Frits F D Daeyaert, Maarten H Vinkers, Koen J A Van Aken, Edward Arnold, Kalyan Das, Amuri Kilonda, Georges J Hoornaert, Frans Compernolle, Marek Cegla, Rasha A Azzam, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Paul A J Janssen | Design, synthesis, and SAR of a novel... | |
| 2005 | Nicolas Sluis-Cremer, Dominique Arion, Urvi Parikh, Dianna Koontz, Raymond F Schinazi, John W Mellors, Michael A. Parniak | The 3'-azido group is not the primary... | |
| 2005 | Cathryn A Shaw-Reid, Bradley Feuston, Vandna Munshi, Krista Getty, Julie Krueger, Daria J Hazuda, Michael A. Parniak, Michael D Miller, Dale Lewis | Dissecting the effects of DNA polymer... | |
| 2005 | Paul A J Janssen, Paul J Lewi, Edward Arnold, Frits F D Daeyaert, Marc R De Jonge, Jan Heeres, Luc Koymans, Maarten H Vinkers, Jérôme Guillemont, Elisabeth Pasquier, Michael Kukla, Don Ludovici, Koen Andries, Marie-Pierre P De Béthune, Rudi Pauwels, Kalyan Das, Arthur D Clark, Yulia Volovik Frenkel, Stephen H Hughes, Bart Medaer, Fons De Knaep, Hilde Bohets, Fred De Clerck, Ann Lampo, Peter Williams, Paul Stoffels | In search of a novel anti-HIV drug: m... | |
| 2005 | Alok Mulky, Stefan G Sarafianos, Yujiang Jia, Edward Arnold, John C Kappes | Identification of amino acid residues... | |
| 2005 | Bo-Liang Deng, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman | Synthesis, anti-HIV activity, and met... | |
| 2005 | Tongfei Wu, Matheus Froeyen, Veerle Kempeneers, Christophe Pannecouque, Jing Wang, Roger Busson, Erik De Clercq, Piet Herdewijn | Deoxythreosyl phosphonate nucleosides... | |
| 2005 | Dan Turner, Bluma G Brenner, Daniela D Moisi, Chen Liang, Mark A. Wainberg | Substitutions in the Reverse Transcri... | |
| 2005 | Mark A. Wainberg, James P C Sawyer, Julio S G Montaner, Robert L Murphy, Daniel R Kuritzkes, Francois Raffi | Challenges for the clinical developme... | |
| 2005 | Rienk E Jeeninga, Barbara Jan, Birgit van der Linden, Henk van den Berg, Ben Berkhout | Construction of a minimal HIV-1 varia... | |
| 2005 | Junmei Wang, Xinshan Kang, Irwin D Kuntz, Peter A Kollman | Hierarchical database screenings for ... | |
| 2005 | Yaofeng Zhao, Yang Jin, Jing-Houng Wang, Rui-Rui Wang, Liu-Meng Yang, Wen-Hui Lee, Yong-Tang Zheng, Yongqing Zhang | A novel heme-containing protein with ... | |
| 2005 | Fernando A Frankel, Bruno Marchand, Dan Turner, Matthias Götte, Mark A. Wainberg | Impaired rescue of chain-terminated D... | |
| 2005 | Abdellah Benjahad, Martine Croisy, Claude Monneret, Emile Bisagni, Dominique Mabire, Sophie Coupa, Alain Poncelet, Imre Csoka, Jérôme Guillemont, Christophe Meyer, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Daniel M Himmel, Kalyan Das, Edward Arnold, Chi Hung Nguyen, David S Grierson | 4-Benzyl and 4-benzoyl-3-dimethylamin... | |
| 2005 | Hong Li, Zhengqiang Wang, Wei-guo Cui, Yan Liang, Tian-yi Xin, Jinming Li | [Study on adherence and interrelated ... | |
| 2005 | Kalyan Das, Paul J Lewi, Stephen H Hughes, Edward Arnold | Crystallography and the design of ant... | |
| 2005 | Andrew R Zolopa, Laura C Lazzeroni, Alex Rinehart, Françoise Brun Vezinet, François Clavel, Ann Collier, Brian Conway, Roy M Gulick, Mark Holodniy, CF Perno, Robert W Shafer, Douglas D Richman, Mark A. Wainberg, Daniel R Kuritzkes | Accuracy, precision, and consistency ... | |
| 2005 | Emmanuele Crespan, Giada A Locatelli, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Drug resistance mutations in the nucl... | |
| 2005 | Antonello Mai, Marino Artico, Rino Ragno, Gianluca Sbardella, Silvio Massa, Chiara Musiu, Massimo Mura, Flavia Marturana, Alessandra Cadeddu, Giovanni Maga, Paolo La Colla | 5-Alkyl-2-alkylamino-6-(2,6-difluorop... | |
| 2005 | Joël Didierjean, Catherine Isel, Flore Querré, Jean-François Mouscadet, Anne-Marie Aubertin, Jean-Yves Valnot, Serge R Piettre, Roland Marquet | Inhibition of human immunodeficiency ... | |
| 2005 | Gabriella De Martino, Giuseppe La Regina, Alessandra Di Pasquali, Rino Ragno, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri | Novel 1-[2-(diarylmethoxy)ethyl]-2-me... | |
| 2005 | Johan Vingerhoets, Hilde Azijn, Els Fransen, Inky De Baere, Liesbet Smeulders, Dirk Jochmans, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune | TMC125 displays a high genetic barrie... | |
| 2005 | Emmanuele Crespan, Samantha Zanoli, Anastasiya Khandazhinskaya, Igor V Shevelev, Maxim Jasko, Ludmila Alexandrova, Marina Kukhanova, Giuseppina Blanca, Giuseppe Villani, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Incorporation of non-nucleoside triph... | |
| 2005 | Natalia A Lebedeva, T A Seredina, V N Silnikov, T V Abramova, A S Levina, Svetlana N Khodyreva, Nadejda I Rechkunova, Olga I Lavrik | Analysis of interactions of DNA polym... | |
| 2005 | Caterina Fattorusso, Sandra Gemma, Stefania Butini, Paul Huleatt, Bruno Catalanotti, Marco Persico, Meri De Angelis, Isabella Fiorini, Vito Nacci, Anna Ramunno, Manuela Rodriquez, Giovanni Greco, Ettore Novellino, Alberto Bergamini, Stefano Marini, Massimo Coletta, Giovanni Maga, Silvio Spadari, Giuseppe Campiani | Specific targeting highly conserved r... | |
| 2004 | Yanping He, Fener Chen, Guangfu Sun, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | 5-Alkyl-2-[(aryl and alkyloxylcarbony... | |
| 2004 | Bruno Marchand, Matthias Götte | Impact of the translocational equilib... | |
| 2004 | Kenji Kitano, Satoru Kohgo, Kohei Yamada, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui | Attempt to reduce cytotoxicity by syn... | |
| 2004 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Effects of mutations in the G tract o... | |
| 2004 | Zandrea Ambrose, Valerie Boltz, Sarah Palmer, John M Coffin, Stephen H Hughes, Vineet N Kewalramani | In vitro characterization of a simian... | |
| 2004 | John G Julias, Paul L Boyer, Mary Jane McWilliams, W Gregory Alvord, Stephen H Hughes | Mutations at position 184 of human im... | |
| 2004 | A Michael Sismour, Stefan Lutz, Jeong-Ho Park, Michael J Lutz, Paul L Boyer, Stephen H Hughes, Steven A Benner | PCR amplification of DNA containing n... | |
| 2004 | Erik De Clercq | Non-nucleoside reverse transcriptase ... | |
| 2004 | Stefan G Sarafianos, Kalyan Das, Stephen H Hughes, Edward Arnold | Taking aim at a moving target: design... | |
| 2004 | Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Marco Petrella, Mark A. Wainberg | Rationale for maintenance of the M184... | |
| 2004 | Esther W Hou, Rajendra Prasad, William A Beard, Samuel H Wilson | High-level expression and purificatio... | |
| 2004 | Jérôme Deval, Jean-Marc Navarro, Boulbaba Selmi, Jérôme Courcambeck, Joëlle Boretto, Philippe Halfon, Sarah Garrido-Urbani, Josephine Sire, Bruno Canard | A loss of viral replicative capacity ... | |
| 2004 | Dan Turner, Bluma G Brenner, Mark A. Wainberg | Relationships among various nucleosid... | |
| 2004 | Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, David K Stammers | Crystal structures of HIV-1 reverse t... | |
| 2004 | Peter R Meyer, Anthony J Smith, Suzanne E Matsuura, Walter A Scott | Effects of primer-template sequence o... | |
| 2004 | Stefan G Sarafianos, Stephen H Hughes, Edward Arnold | Designing anti-AIDS drugs targeting t... | |
| 2004 | Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna-Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà | 2-(2,6-Dihalophenyl)-3-(pyrimidin-2-y... | |
| 2004 | Andrew L Hopkins, Jingshan Ren, John Milton, Richard J Hazen, Joseph H Chan, David I Stuart, David K Stammers | Design of non-nucleoside inhibitors o... | RT,Associated condition,All properties |
| 2004 | George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Kalavathy Sitaraman, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice | Site- and subunit-specific incorporat... | |
| 2004 | CF Perno, Emanuela Balestra, M Francesconi, D Abdelahad, Raffaele Caliò, Jan Balzarini, Stefano Aquaro | Antiviral profile of HIV inhibitors i... | |
| 2004 | Michael B Doughty, Karam Aboudehen, Garland Anderson, Ke Li, Bob Moore, Tina Poolson | Side-chain conformational restriction... | |
| 2004 | Debanu Das, Millie M Georgiadis | The crystal structure of the monomeri... | |
| 2004 | Steve Tuske, Stefan G Sarafianos, Arthur D Clark, Jianping Ding, Lisa K Naeger, Kirsten L White, Michael D Miller, Craig S Gibbs, Paul L Boyer, Patrick K Clark, Gang Wang, Barbara L Gaffney, Roger A Jones, Donald M Jerina, Stephen H Hughes, Edward Arnold | Structures of HIV-1 RT-DNA complexes ... | |
| 2004 | Jérôme Deval, Kirsten L White, Michael D Miller, Neil T Parkin, Jérôme Courcambeck, Philippe Halfon, Boulbaba Selmi, Joëlle Boretto, Bruno Canard | Mechanistic basis for reduced viral a... | |
| 2004 | Jan Balzarini | Current status of the non-nucleoside ... | |
| 2004 | Satoru Kohgo, Kohei Yamada, Kenji Kitano, Yuko Iwai, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui | Design, efficient synthesis, and anti... | |
| 2004 | Jeong-Yun Choi, F Peter Guengerich | Analysis of the effect of bulk at N2-... | |
| 2004 | Joeri Auwerx, Robert Esnouf, Erik De Clercq, Jan Balzarini | Susceptibility of feline immunodefici... | |
| 2004 | María-José Camarasa, Ana San-Félix, Sonsoles Velázquez, María-Jesús Pérez-Pérez, Federico Gago, Jan Balzarini | TSAO compounds: the comprehensive sto... | |
| 2004 | Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà | Synthesis of new 2,3-diaryl-1,3-thiaz... | |
| 2004 | Matthias Götte | Inhibition of HIV-1 reverse transcrip... | |
| 2004 | Lisa F Rezende, Vinayaka R Prasad | Nucleoside-analog resistance mutation... | RT,Associated condition,All properties |
| 2004 | Yanping He, Fener Chen, Xiongjie Yu, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse transcrip... | |
| 2004 | George R Painter, Merrick R Almond, Shuli Mao, Dennis C Liotta | Biochemical and mechanistic basis for... | RT,Associated condition,All properties |
| 2004 | Dan Turner, Bluma G Brenner, Daniela D Moisi, Mervi Detorio, Raymond Cesaire, Takashi Kurimura, Haruyo Mori, Max Essex, Shlomo Maayan, Mark A. Wainberg | Nucleotide and amino acid polymorphis... | |
| 2004 | Louise Z Wang, George L Kenyon, Kenneth A Johnson | Novel mechanism of inhibition of HIV-... | |
| 2004 | Mark A. Wainberg | The impact of the M184V substitution ... | |
| 2004 | Dan Turner, Ariel Roldan, Bluma G Brenner, Daniela D Moisi, Jean-Pierre Routy, Mark A. Wainberg | Variability in the PR and RT genes of... | |
| 2004 | Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Zeev Rosberger, Michel Roger, Mark A. Wainberg | Diminished representation of HIV-1 va... | |
| 2004 | Maqbool A Siddiqui, Stephen H Hughes, Paul L Boyer, Hiroyuki Mitsuya, Que N Van, Clifford George, Stefan G Sarafinanos, Victor E Marquez | A 4'-C-ethynyl-2',3'-dideoxynucleosid... | |
| 2004 | Koen Andries, Hilde Azijn, Theo Thielemans, Donald W Ludovici, Michael Kukla, Jan Heeres, Paul A J Janssen, Bart De Corte, Johan Vingerhoets, Rudi Pauwels, Marie-Pierre P De Béthune | TMC125, a novel next-generation nonnu... | RT,Associated condition,All properties |
| 2004 | Reynel Cancio, Silvio Spadari, Giovanni Maga | Vif is an auxiliary factor of the HIV... | |
| 2004 | Giada A Locatelli, Giuseppe Campiani, Reynel Cancio, Elena Morelli, Anna Ramunno, Sandra Gemma, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Effects of drug resistance mutations ... | |
| 2004 | Giada A Locatelli, Reynel Cancio, Silvio Spadari, Giovanni Maga | HIV-1 reverse transcriptase inhibitor... | |
| 2004 | Julie Qi Hang, Surendran Rajendran, Yanli Yang, Yingqian Li, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin, Klaus Klumpp | Activity of the isolated HIV RNase H ... | |
| 2004 | Paul L Boyer, Tomozumi Imamichi, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Effects of the Delta67 complex of mut... | |
| 2004 | Claudia M D'Abramo, Luciano Cellai, Matthias Götte | Excision of incorporated nucleotide a... | |
| 2004 | Stefania Paolucci, Fausto Baldanti, Giovanni Maga, Reynel Cancio, Maurizio Zazzi, Maurizio Zavattoni, Antonella Chiesa, Silvio Spadari, Giuseppe Gerna | Gln145Met/Leu changes in human immuno... | |
| 2004 | Joy Y Feng, Eisuke Murakami, Suzana M Zorca, Allison A Johnson, Kenneth A Johnson, Raymond F Schinazi, Phillip A Furman, Karen S Anderson | Relationship between antiviral activi... | |
| 2004 | Paul J Lewi, Edward Arnold, Koen Andries, Hilde Bohets, Herman Borghys, Arthur D Clark, Frits F D Daeyaert, Kalyan Das, Marie-Pierre P De Béthune, Marc R De Jonge, Jan Heeres, Luc Koymans, Jos Leempoels, Jef Peeters, Philip Timmerman, Walter Van den Broeck, Frédéric Vanhoutte, Gerben Van't Klooster, Maarten H Vinkers, Yulia Volovik, Paul A J Janssen | Correlations between factors determin... | |
| 2004 | Eisuke Murakami, Adrian S Ray, Raymond F Schinazi, Karen S Anderson | Investigating the effects of stereoch... | |
| 2004 | Erik De Clercq | Antiviral drugs in current clinical use. | |
| 2004 | George A Freeman, C Webster Andrews Iii, Andrew L Hopkins, Gina S Lowell, Lee T Schaller, Jill R Cowan, Stephen S Gonzales, George W Koszalka, Richard J Hazen, Lawrence R Boone, Rob G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, David J Reynolds, John Milton, Jingshan Ren, David I Stuart, David K Stammers, Joseph H Chan | Design of non-nucleoside inhibitors o... | RT,Associated condition,All properties |
| 2004 | Maximilian A Silvestri, Muthukaman Nagarajan, Erik De Clercq, Christophe Pannecouque, Mark Cushman | Design, synthesis, anti-HIV activitie... | |
| 2004 | Kalyan Das, Arthur D Clark, Paul J Lewi, Jan Heeres, Marc R De Jonge, Lucien M H Koymans, H Maarten Vinkers, Frederik Daeyaert, Donald W Ludovici, Michael J Kukla, Bart De Corte, Robert W Kavash, Chih Y Ho, Hong Ye, Mark A Lichtenstein, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Paul L Boyer, Patrick K Clark, Stephen H Hughes, Paul A J Janssen, Edward Arnold | Roles of conformational and positiona... | |
| 2004 | Elena N Peletskaya, Alex A Kogon, Steven Tuske, Edward Arnold, Stephen H Hughes | Nonnucleoside inhibitor binding affec... | RT,Associated condition,All properties |
| 2004 | King C Chan, Scott R Budihas, Stuart F J Le Grice, Michael A. Parniak, Robert J Crouch, Sergei A Gaidamakov, Haleem J Isaaq, Antony Wamiru, James B McMahon, John A Beutler | A capillary electrophoretic assay for... | |
| 2004 | Myriam Witvrouw, Bénédicte Van Maele, J Vercammen, Anke Hantson, Y Engelborghs, Erik De Clercq, Christophe Pannecouque, Zeger Debyser | Novel inhibitors of HIV-1 integration. | |
| 2004 | Elisabetta Bulgheroni, Francesco Croce, Paola Citterio, Ottavia Viganò, Raffaella Visonà, Eugenio Sala, Massimo Galli, Stefano Rusconi | Unusual codon 69 insertions: influenc... | |
| 2004 | Alok Mulky, Stefan G Sarafianos, Edward Arnold, Xiaoming Wu, John C Kappes | Subunit-specific analysis of the huma... | |
| 2004 | Kirsten L White, James M Chen, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Lisa K Naeger, S Swaminathan, Michael D Miller | Molecular mechanisms of tenofovir res... | |
| 2004 | Rachelle J Bienstock, Willliam C Copeland | Molecular insights into NRTI inhibiti... | |
| 2004 | Nicolas Sluis-Cremer, Dominique Arion, Michael E Abram, Michael A. Parniak | Proteolytic processing of an HIV-1 po... | |
| 2004 | Florence Doualla-Bell, Simane Gaseitsiwe, Thumbi Ndungú, Musetsanagepe Modukanele, Trevor Peter, Vladimir Novitsky, Ndwapi Ndwapi, Gaolathe Tendani, Ava Avalos, William Wester, Hermann Bussmann, Peter Cardiello, Richard G Marlink, Howard Moffat, Ibou Thior, Mark A. Wainberg, Max Essex | Mutations and polymorphisms associate... | |
| 2004 | Joeri Auwerx, Miguel Stevens, An R Van Rompay, Louise E Bird, Jingshan Ren, Erik De Clercq, Bo Oberg, David K Stammers, Anna Karlsson, Jan Balzarini | The phenylmethylthiazolylthiourea non... | |
| 2003 | Stefania Paolucci, Fausto Baldanti, Marco Tinelli, Giovanni Maga, Giuseppe Gerna | Detection of a new HIV-1 reverse tran... | |
| 2003 | Marie-Pierre Golinelli, Stephen H Hughes | Secondary structure in the nucleic ac... | |
| 2003 | Sanjay U C Sankatsing, Gerrit J Weverling, Monika Peeters, Gerben van't Klooster, Boris Gruzdev, Aza Rakhmanova, Sven A Danner, Suzanne Jurriaans, Jan M Prins, Joep M A Lange | TMC125 exerts similar initial antivir... | |
| 2003 | Giuseppina Blanca, Igor V Shevelev, Kristijan Ramadan, Giuseppe Villani, Silvio Spadari, Ulrich Hübscher, Giovanni Maga | Human DNA polymerase lambda diverged ... | |
| 2003 | Marie L Coté, Mark Pflomm, Millie M Georgiadis | Staying straight with A-tracts: a DNA... | |
| 2003 | Lingling Shen, Jianhua Shen, Xiaomin Luo, Feng Cheng, Yechun Xu, Kaixian Chen, Edward Arnold, Jianping Ding, Hualiang Jiang | Steered molecular dynamics simulation... | |
| 2003 | Angelo Ranise, Andrea Spallarossa, Silvia Schenone, Olga Bruno, Francesco Bondavalli, Laura Vargiu, Tiziana Marceddu, Massimo Mura, Paolo La Colla, Alessandra Pani | Design, synthesis, SAR, and molecular... | |
| 2003 | Adrian S Ray, Eisuke Murakami, Aravind Basavapathruni, Joseph A Vaccaro, Dagny Ulrich, Chung K Chu, Raymond F Schinazi, Karen S Anderson | Probing the molecular mechanisms of A... | |
| 2003 | Harold R Lee, Jeremiah Hanes, Kenneth A Johnson | Toxicity of nucleoside analogues used... | |
| 2003 | Jan Balzarini, Erik De Clercq, Beata Kaminska, Andrzej Orzeszko | Synthesis and antiviral activity of s... | |
| 2003 | Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini | Inhibition of human immunodeficiency ... | |
| 2003 | Evguenia S Svarovskaia, Sara R Cheslock, Wen-Hui Zhang, Wei-Shau Hu, Vinay K Pathak | Retroviral mutation rates and reverse... | |
| 2003 | Mélanie Girouard, Karidia Diallo, Bruno Marchand, Suzanne McCormick, Matthias Götte | Mutations E44D and V118I in the rever... | |
| 2003 | Eisuke Murakami, Joy Y Feng, Harold R Lee, Jeremiah Hanes, Kenneth A Johnson, Karen S Anderson | Characterization of novel reverse tra... | |
| 2003 | Peter R Meyer, Suzanne E Matsuura, Dianna Zonarich, Rahul R Chopra, Eric Pendarvis, Holly Z Bazmi, John W Mellors, Walter A Scott | Relationship between 3'-azido-3'-deox... | |
| 2003 | Ge Meng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse transcrip... | |
| 2003 | Koyo Ariyoshi, Masakazu Matsuda, Hideka Miura, Sachiko Tateishi, Kaneo Yamada, Wataru Sugiura | Patterns of point mutations associate... | |
| 2003 | Wei Huang, Andrea Gamarnik, Kay Limoli, Christos J Petropoulos, Jeannette M Whitcomb | Amino acid substitutions at position ... | |
| 2003 | Marilyn B Kroeger Smith, Sandra Ruby, Stanislav Horouzhenko, Bryan Buckingham, Julia Richardson, Ina Puleri, Emily Potts, William L Jorgensen, Edward Arnold, Weiming Zhang, Stephen H Hughes, Christopher J Michejda, Richard H Smith | HIV-1 reverse transcriptase variants:... | |
| 2003 | Marilyn B Kroeger Smith, Brian M Hose, Arie Hawkins, James Lipchock, David W Farnsworth, Robert C Rizzo, Julian Tirado-Rives, Edward Arnold, Weiming Zhang, Stephen H Hughes, William L Jorgensen, Christopher J Michejda, Richard H Smith | Molecular modeling calculations of HI... | |
| 2003 | Irene M Lagoja, Christophe Pannecouque, Arthur Van Aerschot, Myriam Witvrouw, Zeger Debyser, Jan Balzarini, Piet Herdewijn, Erik De Clercq | N-aminoimidazole derivatives inhibiti... | |
| 2003 | Romas Geleziunas, Karen Gallagher, Hangchun Zhang, Lee Bacheler, Sena Garber, Jing-Tao Wu, Guoen Shi, Michael J Otto, Raymond F Schinazi, Susan Erickson-Viitanen | HIV-1 resistance profile of the novel... | |
| 2003 | Maria Letizia Barreca, Alba Chimirri, Erik De Clercq, Laura De Luca, Anna-Maria Monforte, Pietro Monforte, Angela Rao, Maria Zappalà | Anti-HIV agents: design and discovery... | |
| 2003 | Cathryn A Shaw-Reid, Vandna Munshi, Pia Graham, Abigail Wolfe, Marc Witmer, Renee Danzeisen, David B Olsen, Steven S Carroll, Mark Embrey, John S Wai, Michael D Miller, James L Cole, Daria J Hazuda | Inhibition of HIV-1 ribonuclease H by... | |
| 2003 | Susan E Lim, Mikhail V Ponamarev, Matthew J Longley, William C Copeland | Structural determinants in human DNA ... | |
| 2003 | Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, Jingshan Ren, David I Stuart, David K Stammers | Cloning, expression, purification, an... | |
| 2003 | Nicolas Sluis-Cremer, Ellis Kempner, Michael A. Parniak | Structure-activity relationships in H... | |
| 2003 | Michael A. Parniak, Kyung-Lyum Min, Scott R Budihas, Stuart F J Le Grice, John A Beutler | A fluorescence-based high-throughput ... | |
| 2003 | Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Mutations in the 5' end of the human ... | |
| 2003 | Tokumi Maruyama, Shigetada Kozai, Tetsuo Yamasaki, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoeck, Graciella Andrei, Erik De Clercq | Synthesis and antiviral activity of 1... | |
| 2003 | María-Cruz Bonache, Cristina Chamorro, Esther Lobatón, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, Ana San-Félix | Structure-activity relationship studi... | |
| 2003 | Joel E Gallant, Peter Z Gerondelis, Mark A. Wainberg, Nancy S Shulman, Richard H Haubrich, Marty St Clair, Ernest R Lanier, Nicholas S Hellmann, Douglas D Richman | Nucleoside and nucleotide analogue re... | RT,Associated condition,All properties |
| 2003 | Jaroslaw Poznanski, Maria Bretner, Tadeusz Kulikowski, Jan Balzarini, Arthur Van Aerschot, Erik De Clercq | Synthesis, solution conformation and ... | |
| 2003 | Boulbaba Selmi, Jerome Deval, Karine Alvarez, Joelle Boretto, Simon Sarfati, Catherine Guerreiro, Bruno Canard | The Y181C substitution in 3'-azido-3'... | |
| 2003 | Giuseppina Blanca, Fausto Baldanti, Stefania Paolucci, Alexander Yu Skoblov, Lyubov Victorova, Ulrich Hübscher, Giuseppe Gerna, Silvio Spadari, Giovanni Maga | Nevirapine resistance mutation at cod... | |
| 2003 | Martin Stürmer, Schlomo Staszewski, Hans-Wilhelm Doerr, Brendan A Larder, Stuart Bloor, Kurt Hertogs | Correlation of phenotypic zidovudine ... | |
| 2003 | Bluma G Brenner, Dan Turner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Mauricio Carobene, Richard G Marlink, Jonathan Schapiro, Michel Roger, Mark A. Wainberg | A V106M mutation in HIV-1 clade C vir... | |
| 2003 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Mutation of amino acids in the connec... | |
| 2003 | Yudong Quan, Bluma G Brenner, Maureen Oliveira, Mark A. Wainberg | Lamivudine can exert a modest antivir... | |
| 2003 | Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini | Novel human immunodeficiency virus (H... | |
| 2003 | J Gerardo García-Lerma, Hamish MacInnes, Diane Bennett, Patrick Reid, Soumya Nidtha, Hillard Weinstock, Jonathan E Kaplan, Walid Heneine | A novel genetic pathway of human immu... | |
| 2003 | Bruno Marchand, Matthias Götte | Site-specific footprinting reveals di... | |
| 2003 | Karidia Diallo, Bluma G Brenner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Matthias Götte, Mark A. Wainberg | The M184V substitution in human immun... | |
| 2003 | William A Beard, Samuel H Wilson | Structural insights into the origins ... | |
| 2003 | Qian Zhao, Hong Lu, Dominique Schols, Erik De Clercq, Shibo Jiang | Development of a cell-based enzyme-li... | |
| 2003 | Karidia Diallo, Bruno Marchand, Xin Wei, Luciano Cellai, Matthias Götte, Mark A. Wainberg | Diminished RNA primer usage associate... | |
| 2003 | Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg | Negative effect of the M184V mutation... | |
| 2003 | Adrian S Ray, Raymond F Schinazi, Eisuke Murakami, Aravind Basavapathruni, Junxing Shi, Suzana M Zorca, Chung K Chu, Karen S Anderson | Probing the mechanistic consequences ... | RT,Associated condition,All properties |
| 2003 | Myriam Witvrouw, Christophe Pannecouque, Valery Fikkert, Anke Hantson, Barbara Van Remoortel, Marjan Hezareh, Erik De Clercq, Stephen J Brown | Potent and selective inhibition of HI... | |
| 2003 | Yongseok Choi, Clifford George, Maria J Comin, Joseph J Barchi, Hak Sung Kim, Kenneth A Jacobson, Jan Balzarini, Hiroyuki Mitsuya, Paul L Boyer, Stephen H Hughes, Victor E Marquez | A conformationally locked analogue of... | |
| 2003 | Peter R Meyer, Johan Lennerstrand, Suzanne E Matsuura, Brendan A Larder, Walter A Scott | Effects of dipeptide insertions betwe... | |
| 2003 | Klaus Klumpp, Julie Qi Hang, Surendran Rajendran, Yanli Yang, Andre Derosier, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin | Two-metal ion mechanism of RNA cleava... | |
| 2002 | Jason W Rausch, Daniela Lener, Jennifer T Miller, John G Julias, Stephen H Hughes, Stuart F J Le Grice | Altering the RNase H primer grip of h... | |
| 2002 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Nucleoside analog resistance caused b... | |
| 2002 | Lisa K Naeger, Nicolas A Margot, Michael D Miller | ATP-dependent removal of nucleoside r... | |
| 2002 | Adrienne M Woodside, F Peter Guengerich | Misincorporation and stalling at O(6)... | |
| 2002 | Adrian S Ray, Aravind Basavapathruni, Karen S Anderson | Mechanistic studies to understand the... | |
| 2002 | Nobuyuki Kasai, Yoshiyuki Mizushina, Fumio Sugawara, Kengo Sakaguchi | Three-dimensional structural model an... | |
| 2002 | Erik De Clercq | Highlights in the development of new ... | |
| 2002 | N McLellan, Xin Wei, Bruno Marchand, Mark A. Wainberg, Matthias Götte | Nonradioactive detection of retrovira... | |
| 2002 | Giovanni Maga, Silvio Spadari | Combinations against combinations: as... | |
| 2002 | Marie-Pierre Golinelli, Stephen H Hughes | Nontemplated nucleotide addition by H... | |
| 2002 | Phillip P Chamberlain, Jingshan Ren, Charles E Nichols, L Douglas, Johan Lennerstrand, Brendan A Larder, David I Stuart, David K Stammers | Crystal structures of Zidovudine- or ... | |
| 2002 | Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak | Destabilization of the HIV-1 reverse ... | |
| 2002 | Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg | Polymorphisms of cytotoxic T-lymphocy... | |
| 2002 | Laurent Andréoletti, Laurence Weiss, Ali Si-Mohamed, Christophe Piketty, Thierry Prazuck, Gérard Calamy, Jean-Elie Malkin, Mathieu Matta, François-Xavier Mbopi-Kéou, François Clavel, Michel D Kazatchkine, Laurent Bélec | Multidrug-resistant HIV-1 RNA and pro... | |
| 2002 | Janina Cramer, Michael Strerath, Andreas Marx, Tobias Restle | Exploring the effects of active site ... | RT,Associated condition,All properties |
| 2002 | Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg | Co-receptor usage and HIV-1 intra-cla... | |
| 2002 | Christophe Pannecouque, Wim Pluymers, Bénédicte Van Maele, Victor Tetz, Peter Cherepanov, Erik De Clercq, Myriam Witvrouw, Zeger Debyser | New class of HIV integrase inhibitors... | |
| 2002 | R Masciari, L Cosco, M C Diaco, Dora N Della, T Ferraro, T Raimondi, B Ruperti, E Santandrea | HIV-1: a case of RT67 deletion in a m... | |
| 2002 | Zeger Debyser, Peter Cherepanov, Bénédicte Van Maele, Erik De Clercq, Myriam Witvrouw | In search of authentic inhibitors of ... | |
| 2002 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Mutations in the RNase H domain of HI... | |
| 2002 | Robert L Lobato, Eun-Young Kim, Ronald M Kagan, Thomas C Merigan | Genotypic and phenotypic analysis of ... | |
| 2002 | Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg | The M184V mutation in HIV-1 reverse t... | |
| 2002 | Patrick K O'Neil, Guoli Sun, Hong Yu, Yacov Ron, Joseph P Dougherty, Bradley D Preston | Mutational analysis of HIV-1 long ter... | |
| 2002 | Karen S Anderson | Perspectives on the molecular mechani... | RT,Associated condition,All properties |
| 2002 | A Geoffrey Skillman, Karl W Maurer, Diana C Roe, Margaret J Stauber, Dolan Eargle, Todd J A Ewing, Angelika Muscate, Elisabeth Davioud-Charvet, Maxine V Medaglia, Robert J Fisher, Edward Arnold, Hong Qiang Gao, Robert W Buckheit, Paul L Boyer, Stephen H Hughes, Irwin D Kuntz, George L Kenyon | A novel mechanism for inhibition of H... | |
| 2002 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | The M184V mutation reduces the select... | |
| 2002 | Marinela Perpelescu, Jun'ichi Kobayashi, Miho Furuta, Yasutomo Ito, Shunji Izuta, Masaharu Takemura, Motoshi Suzuki, Shonen Yoshida | Novel phenalenone derivatives from a ... | |
| 2002 | Bluma G Brenner, Dan Turner, Mark A. Wainberg | HIV-1 drug resistance: can we overcome? | |
| 2002 | Janice D Pata, Bradford R King, Thomas A Steitz | Assembly, purification and crystalliz... | |
| 2002 | Timothy S Fisher, Vinayaka R Prasad | Substitutions of Phe61 located in the... | RT,Associated condition,All properties |
| 2002 | Michael Strerath, Janina Cramer, Tobias Restle, Andreas Marx | Implications of active site constrain... | |
| 2002 | Fabienne Brulé, Roland Marquet, Liwei Rong, Mark A. Wainberg, Bernard P Roques, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann | Structural and functional properties ... | |
| 2002 | Erik De Clercq | New developments in anti-HIV chemothe... | |
| 2002 | Adrienne M Woodside, F Peter Guengerich | Effect of the O6 substituent on misin... | |
| 2002 | Christopher J Hollowood, Steven V Ley, Shigeo Yamanoi | Synthesis of taurospongin A: a potent... | |
| 2002 | Erik De Clercq | New anti-HIV agents and targets. | |
| 2002 | Wim Pluymers, Godwin Pais, Bénédicte Van Maele, Christophe Pannecouque, Valery Fikkert, Terrence R Burke, Erik De Clercq, Myriam Witvrouw, Nouri Neamati, Zeger Debyser | Inhibition of human immunodeficiency ... | |
| 2002 | Peter R Meyer, Suzanne E Matsuura, Adviye A Tolun, Ingrid Pfeifer, Antero G So, John W Mellors, Walter A Scott | Effects of specific zidovudine resist... | |
| 2002 | P Richard Harrigan, Mahboob Salim, David K Stammers, Brian Wynhoven, Zabrina L Brumme, Paula McKenna, Brendan A Larder, S D Kemp | A mutation in the 3' region of the hu... | |
| 2002 | Joke Snoeck, Sonia Van Dooren, Kristel Van Laethem, Inge Derdelinckx, Eric Van Wijngaerden, Erik De Clercq, Anne-Mieke Vandamme | Prevalence and origin of HIV-1 group ... | |
| 2002 | Qingli Shi, Kamalendra Singh, Aashish Srivastava, Neerja Kaushik, Mukund J Modak | Lysine 152 of MuLV reverse transcript... | |
| 2002 | Joeri Auwerx, Thomas W North, Bradley D Preston, George J Klarmann, Erik De Clercq, Jan Balzarini | Chimeric human immunodeficiency virus... | |
| 2002 | Yoshiyuki Mizushina, Chikako Murakami, Keisuke Ohta, Hirosato Takikawa, Kenji Mori, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi | Selective inhibition of the activitie... | |
| 2002 | Mickael Rigourd, Chantal Ehresmann, Michael A. Parniak, Bernard Ehresmann, Roland Marquet | Primer unblocking and rescue of DNA s... | |
| 2002 | Giuseppe Campiani, Anna Ramunno, Giovanni Maga, Vito Nacci, Caterina Fattorusso, Bruno Catalanotti, Elena Morelli, Ettore Novellino | Non-nucleoside HIV-1 reverse transcri... | |
| 2002 | Stefano Aquaro, Raffaele Caliò, Jan Balzarini, Maria Concetta Bellocchi, Enrico Garaci, CF Perno | Macrophages and HIV infection: therap... | |
| 2002 | Kirsten L White, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Michael D Miller, Lisa K Naeger | Molecular mechanisms of resistance to... | |
| 2002 | Brigitte Montes, Michel Segondy | Prevalence of the mutational pattern ... | |
| 2002 | Dominique Arion, Nicolas Sluis-Cremer, Kyung-Lyum Min, Michael E Abram, Ronald S Fletcher, Michael A. Parniak | Mutational analysis of Tyr-501 of HIV... | |
| 2002 | Dimitrios Motakis, Michael A. Parniak | A tight-binding mode of inhibition is... | |
| 2002 | Jingshan Ren, Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, David I Stuart, David K Stammers | Structure of HIV-2 reverse transcript... | |
| 2002 | L Menéndez-Arias | Molecular basis of fidelity of DNA sy... | |
| 2002 | Marie-Pierre Golinelli, Stephen H Hughes | Nontemplated base addition by HIV-1 R... | |
| 2002 | Koen K A Van Rompay, Tim B Matthews, Joanne Higgins, Don R Canfield, Ross P Tarara, Mark A. Wainberg, Raymond F Schinazi, Niels C Pedersen, Thomas W North | Virulence and reduced fitness of simi... | |
| 2002 | Esther Lobatón, Fátima Rodríguez-Barrios, Federico Gago, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez | Synthesis of 3' '-substituted TSAO de... | |
| 2002 | Yven Van Herrewege, Lieve Penne, Chris Vereecken, Katrien Fransen, Guido van der Groen, Luc Kestens, Jan Balzarini, Guido Vanham | Activity of reverse transcriptase inh... | |
| 2002 | Antonio Mas, Blanca M Vázquez-Alvarez, Esteban Domingo, L Menéndez-Arias | Multidrug-resistant HIV-1 reverse tra... | |
| 2002 | Jimmy Lindberg, Snaevar Sigurdsson, Seved Löwgren, Hans O Andersson, Christer Sahlberg, Rolf Noréen, Kerstin Fridborg, Haijiang Zhang, Torsten Unge | Structural basis for the inhibitory e... | |
| 2002 | Louis M Mansky | HIV mutagenesis and the evolution of ... | |
| 2002 | Stefan G Sarafianos, Arthur D Clark, Kalyan Das, Steve Tuske, Jens J Birktoft, Palanichamy Ilankumaran, Andagar R Ramesha, Jane M Sayer, Donald M Jerina, Paul L Boyer, Stephen H Hughes, Edward Arnold | Structures of HIV-1 reverse transcrip... | |
| 2001 | J Y Wang, Hong Ling, Wei Wen Yang, R Craigie | Structure of a two-domain fragment of... | |
| 2001 | K E Squires | An introduction to nucleoside and nuc... | |
| 2001 | Johan Lennerstrand, Kurt Hertogs, David K Stammers, Brendan A Larder | Correlation between viral resistance ... | |
| 2001 | Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | RNase H cleavage of the 5' end of the... | |
| 2001 | Stefan G Sarafianos, Kalyan Das, C Tantillo, Arthur D Clark, Jianping Ding, J M Whitcomb, Paul L Boyer, Stephen H Hughes, Edward Arnold | Crystal structure of HIV-1 reverse tr... | |
| 2001 | Jingshan Ren, C Nichols, L Bird, P Chamberlain, Kurt L Weaver, S Short, David I Stuart, David K Stammers | Structural mechanisms of drug resista... | |
| 2001 | Ei-Ichi Kodama, Satoru Kohgo, Kenji Kitano, H Machida, Hiroyuki Gatanaga, S Shigeta, Masao Matsuoka, Hiroshi Ohrui, Hiroyuki Mitsuya | 4'-Ethynyl nucleoside analogs: potent... | |
| 2001 | J L Hammond, D L Koontz, Holly Z Bazmi, J R Beadle, S E Hostetler, G D Kini, Kathy A Aldern, Douglas D Richman, Karl Y Hostetler, John W Mellors | Alkylglycerol prodrugs of phosphonofo... | |
| 2001 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Selective excision of AZTMP by drug-r... | |
| 2001 | M Lavigne, L Polomack, H Buc | Structures of complexes formed by HIV... | |
| 2001 | M Gutiérrez-Rivas, L Menéndez-Arias | A mutation in the primer grip region ... | |
| 2001 | Hiroshi Ohrui, Hiroyuki Mitsuya | 4'-C-substituted-2'-deoxynucleosides:... | |
| 2001 | Paul L Boyer, Hong Qiang Gao, Patrick K Clark, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | YADD mutants of human immunodeficienc... | |
| 2001 | V Molteni, J Greenwald, D Rhodes, Y Hwang, W Kwiatkowski, F D Bushman, J S Siegel, S Choe | Identification of a small-molecule bi... | |
| 2001 | Stephen H Hughes | Molecular matchmaking: NNRTIs can enh... | |
| 2001 | Lisa K Naeger, Michael D Miller | Mechanisms of HIV-1 nucleoside revers... | |
| 2001 | G Tachedjian, M Orlova, Stefan G Sarafianos, Edward Arnold, S P Goff | Nonnucleoside reverse transcriptase i... | |
| 2001 | Matthias Götte, Masanori Kameoka, N McLellan, Luciano Cellai, Mark A. Wainberg | Analysis of efficiency and fidelity o... | |
| 2001 | R Hobi, Ulrich Hübscher, K Neftel, E Alteri, B Poncioni, M R Walker, K Woods-Cook, P Schneider, J K Lazdins | Anti-HIV-1 activity in vitro of cefta... | |
| 2001 | Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Paul L Boyer, Paul Lewi, Paul A J Janssen, Jörg-Peter Kleim, M Rösner, Stephen H Hughes, Edward Arnold | The Lys103Asn mutation of HIV-1 RT: a... | |
| 2001 | Li Fan, Laurie S Kaguni | Multiple regions of subunit interacti... | |
| 2001 | Donald W Ludovici, Robert W Kavash, Michael J Kukla, Chih Y Ho, Hong Ye, B L De Corte, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, H E Moereels, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Paul J Lewi, Kalyan Das, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | J E Fitzgibbon, B DiCola, Edward Arnold, Kalyan Das, B E Sha, J C Pottage, R Nahass, S Gaur, J F John | HIV-1 reverse transcriptase mutations... | |
| 2001 | Donald W Ludovici, Michael J Kukla, P G Grous, S Krishnan, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Erik De Clercq, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | Joseph H Chan, J S Hong, R N Hunter , G F Orr, Jill R Cowan, D B Sherman, S M Sparks, B E Reitter, C Webster Andrews, Richard J Hazen, M St Clair, Lawrence R Boone, Robert G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, R J Ott, Jingshan Ren, A Hopkins, David I Stuart, David K Stammers | 2-Amino-6-arylsulfonylbenzonitriles a... | |
| 2001 | I A Drachkova, Irina O Petruseva, I V Safronov, A L Zakharenko, G V Shishkin, Olga I Lavrik, Svetlana N Khodyreva | [Reagents for modification of protein... | |
| 2001 | Z Sevilya, S Loya, Stephen H Hughes, A Hizi | The ribonuclease H activity of the re... | |
| 2001 | Paul L Boyer, Hong Qiang Gao, P Frank, Patrick K Clark, Stephen H Hughes | The basic loop of the RNase H domain ... | |
| 2001 | M Madrid, J A Lukin, J D Madura, Jianping Ding, Edward Arnold | Molecular dynamics of HIV-1 reverse t... | |
| 2001 | Elena N Peletskaya, Paul L Boyer, Alex A Kogon, Patrick K Clark, Heiko Kroth, Jane M Sayer, Donald M Jerina, Stephen H Hughes | Cross-linking of the fingers subdomai... | |
| 2001 | M D Driscoll, Marie-Pierre Golinelli, Stephen H Hughes | In vitro analysis of human immunodefi... | |
| 2001 | Phillip A Furman, J Jeffrey, L L Kiefer, Joy Y Feng, Karen S Anderson, K Borroto-Esoda, E Hill, William C Copeland, Chung K Chu, J P Sommadossi, I Liberman, Raymond F Schinazi, George R Painter | Mechanism of action of 1-beta-D-2,6-d... | |
| 2001 | Catherine Isel, Chantal Ehresmann, P Walter, Bernard Ehresmann, Roland Marquet | The emergence of different resistance... | |
| 2001 | Giovanni Maga, Anna Ramunno, Vito Nacci, Giada A Locatelli, Silvio Spadari, Isabella Fiorini, Fausto Baldanti, Stefania Paolucci, Maurizio Zavattoni, Alberto Bergamini, Bruno Galletti, S Muck, Ulrich Hubscher, Gianluca Giorgi, G Guiso, S Caccia, Giuseppe Campiani | The stereoselective targeting of a sp... | |
| 2001 | Masanori Kameoka, Liwei Rong, Matthias Götte, Chen Liang, Rodney S Russell, Mark A. Wainberg | Role for human immunodeficiency virus... | |
| 2001 | Taurai Tasara, Giovanni Maga, Michael O Hottiger, Ulrich Hübscher | HIV-1 reverse transcriptase and integ... | |
| 2001 | Donald W Ludovici, B L De Corte, Michael J Kukla, Hong Ye, Chih Y Ho, Mark A Lichtenstein, Robert W Kavash, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Kalyan Das, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | Giuseppe Campiani, F Aiello, M Fabbrini, Elena Morelli, Anna Ramunno, S Armaroli, Vito Nacci, A Garofalo, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, L Ventura, B Bongiovanni, M Capozzi, F Bolacchi, Stefano Marini, Massimo Coletta, G Guiso, S Caccia | Quinoxalinylethylpyridylthioureas (QX... | |
| 2001 | Jennifer T Miller, Bernard Ehresmann, Ulrich Hübscher, Stuart F J Le Grice | A novel interaction of tRNA(Lys,3) wi... | |
| 2001 | A L Zakharenko, Dmitry M Kolpashchikov, Svetlana N Khodyreva, Olga I Lavrik, L Menéndez-Arias | Investigation of the dNTP-binding sit... | |
| 2001 | Liwei Rong, Chen Liang, M Hsu, Xiaofeng Guo, Bernard P Roques, Mark A. Wainberg | HIV-1 nucleocapsid protein and the se... | |
| 2001 | G H Kijak, S E Pampuro, M M Avila, C Zala, P Cahn, Mark A. Wainberg, H Salomón | Resistance profiles to antiretroviral... | |
| 2001 | Alba Chimirri, Pietro Monforte, Angela Rao, Maria Zappalà, Anna-Maria Monforte, G De Sarro, Christophe Pannecouque, Myriam Witvrouw, Jan Balzarini, Erik De Clercq | Synthesis, biological activity, pharm... | |
| 2001 | Jan Balzarini, Erik De Clercq | Rapid alternation of drug therapy is ... | |
| 2001 | Cristina Chamorro, Esther Lobatón, María-Cruz Bonache, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, Ana San-Félix, María-José Camarasa | Identification of a novel family of n... | |
| 2001 | H Pelemans, Robert Esnouf, K L Min, M Parniak, Erik De Clercq, Jan Balzarini | Mutations at amino acid positions 63,... | |
| 2001 | Erik De Clercq | New developments in anti-HIV chemothe... | |
| 2001 | A Martinez, C Gil, A Castro, C Perez, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq | Anti-HIV-1 activity of benzothiadiazi... | |
| 2001 | H Pelemans, A Aertsen, Kristel Van Laethem, A-M Vandamme, Erik De Clercq, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, María-José Camarasa, Jan Balzarini | Site-directed mutagenesis of human im... | |
| 2001 | Fátima Rodríguez-Barrios, C Pérez, Esther Lobatón, Sonsoles Velázquez, Cristina Chamorro, Ana San-Félix, María-Jesús Pérez-Pérez, María-José Camarasa, H Pelemans, Jan Balzarini, Federico Gago | Identification of a putative binding ... | |
| 2001 | Jan Balzarini, María-José Camarasa, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, CF Perno, Erik De Clercq, J N Anderson, Anna Karlsson | Exploitation of the low fidelity of h... | |
| 2001 | Wim Pluymers, Erik De Clercq, Zeger Debyser | HIV-1 integration as a target for ant... | |
| 2001 | Erik De Clercq, Dominique Schols | Inhibition of HIV infection by CXCR4 ... | |
| 2001 | L Menéndez-Arias, A Abraha, ME Quiñones-Mateu, Antonio Mas, M J Camarasa, E J Arts | Functional characterization of chimer... | |
| 2000 | Erik De Clercq | Current lead natural products for the... | |
| 2000 | Matthias Götte, Mark A. Wainberg | Biochemical mechanisms involved in ov... | |
| 2000 | K Nozawa, Motoshi Suzuki, Masaharu Takemura, Shonen Yoshida | In vitro expansion of mammalian telom... | |
| 2000 | Paul L Boyer, Stephen H Hughes | Effects of amino acid substitutions a... | |
| 2000 | Ming Yu, W Kabat, Jian Wang | [Rapid detection of drug resistant HI... | |
| 2000 | N Richard, H Salomon, Maureen Oliveira, R Rando, T Mansour, Z Gu, Mark A. Wainberg | Selection of resistance-conferring mu... | |
| 2000 | K Van Vaerenbergh, Kristel Van Laethem, J Albert, Charles A B Boucher, B Clotet, M Floridia, J Gerstoft, B Hejdeman, C Nielsen, Christophe Pannecouque, L Perrin, M F Pirillo, L Ruiz, J C Schmit, F Schneider, A Schoolmeester, Rob Schuurman, H J Stellbrink, L Stuyver, J Van Lunzen, Barbara Van Remoortel, Eric Van Wijngaerden, S Vella, Myriam Witvrouw, Sabine Yerly, Erik De Clercq, J Destmyer, Anne-Mieke Vandamme | Prevalence and characteristics of mul... | |
| 2000 | N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of hum... | |
| 2000 | Holly Z Bazmi, J L Hammond, S C Cavalcanti, Chung K Chu, Raymond F Schinazi, John W Mellors | In vitro selection of mutations in th... | |
| 2000 | Nicolas Sluis-Cremer, Dominique Arion, Neerja Kaushik, H Lim, Michael A. Parniak | Mutational analysis of Lys65 of HIV-1... | |
| 2000 | Kurt Hertogs, Stuart Bloor, V De Vroey, C van Den Eynde, Pascale Dehertogh, A van Cauwenberge, Martin Stürmer, T Alcorn, S Wegner, M van Houtte, V Miller, Brendan A Larder | A novel human immunodeficiency virus ... | |
| 2000 | C E Cases-Gonzalez, M Gutierrez-Rivas, L Menéndez-Arias | Coupling ribose selection to fidelity... | |
| 2000 | T Imamichi, T Sinha, H Imamichi, Y M Zhang, J A Metcalf, J Falloon, H C Lane | High-level resistance to 3'-azido-3'-... | |
| 2000 | E P Coakley, J M Gillis, S M Hammer | Phenotypic and genotypic resistance p... | |
| 2000 | Neerja Kaushik, K Chowdhury, V N Pandey, Mukund J Modak | Valine of the YVDD motif of moloney m... | |
| 2000 | Kamalendra Singh, Neerja Kaushik, J Jin, M Madhusudanan, Mukund J Modak | Role of Q190 of MuLV RT in ddNTP resi... | |
| 2000 | V Miller, M Ait-Khaled, C Stone, P Griffin, D Mesogiti, A Cutrell, R Harrigan, Schlomo Staszewski, C Katlama, G Pearce, M Tisdale | HIV-1 reverse transcriptase (RT) geno... | |
| 2000 | H Jonckheere, J Anné, Erik De Clercq | The HIV-1 reverse transcription (RT) ... | |
| 2000 | Matthias Götte, Dominique Arion, Michael A. Parniak, Mark A. Wainberg | The M184V mutation in the reverse tra... | |
| 2000 | Myriam Witvrouw, Christophe Pannecouque, J Desmyter, Erik De Clercq, Koen Andries | In vitro evaluation of the effect of ... | |
| 2000 | Jan Balzarini | Evaluation of Compounds Against Recom... | |
| 2000 | A Casimiro-Garcia, Erik De Clercq, Christophe Pannecouque, Myriam Witvrouw, T L Stup, J A Turpin, Robert W Buckheit, Mark Cushman | Synthesis and anti-HIV activity of co... | |
| 2000 | D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando | Drug resistance and drug combination ... | |
| 2000 | H Jonckheere, Erik De Clercq, J Anné | Fidelity analysis of HIV-1 reverse tr... | |
| 2000 | A-M Vandamme, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Kristel Van Laethem, J C Schmit, J Desmyter, Erik De Clercq | Evaluating Clinical Isolates for Thei... | |
| 2000 | Jingshan Ren, J Diprose, J Warren, R M Esnouf, Louise E Bird, Shinji Ikemizu, M Slater, John Milton, Jan Balzarini, David I Stuart, David K Stammers | Phenylethylthiazolylthiourea (PETT) n... | |
| 2000 | W R Davis, J Tomsho, S Nikam, E M Cook, D Somand, J A Peliska | Inhibition of HIV-1 reverse transcrip... | |
| 2000 | Myriam Witvrouw, Valery Fikkert, Wim Pluymers, B Matthews, K Mardel, Dominique Schols, J Raff, Zeger Debyser, Erik De Clercq, G Holan, Christophe Pannecouque | Polyanionic (i.e., polysulfonate) den... | |
| 2000 | T V Rao, M T Haber, Jane M Sayer, Donald M Jerina | Incorporation of 4-thiothymidine into... | |
| 2000 | Christos J Petropoulos, N T Parkin, K L Limoli, Y S Lie, Terri Wrin, Wei Huang, H Tian, D Smith, G A Winslow, D J Capon, Jeannette M Whitcomb | A novel phenotypic drug susceptibilit... | |
| 2000 | P Bonfanti, I Faggion, S La Seta Catamancio, M Violin, C Balotta, S Rusconi | Response to antiretroviral therapy in... | |
| 2000 | H Salomon, Mark A. Wainberg, Bluma G Brenner, Yudong Quan, D Rouleau, P Coté, R LeBlanc, E Lefebvre, Bonnie Spira, C Tsoukas, Rafick-Pierre Sekaly, Brian Conway, D Mayers, Jean-Pierre Routy | Prevalence of HIV-1 resistant to anti... | |
| 2000 | Antonio Mas, M Parera, C Briones, V Soriano, Miguel Angel Martínez, Esteban Domingo, L Menéndez-Arias | Role of a dipeptide insertion between... | |
| 2000 | Neerja Kaushik, T T Talele, P K Pandey, D Harris, P N Yadav, V N Pandey | Role of glutamine 151 of human immuno... | |
| 2000 | L Mu, Stefan G Sarafianos, Marc C Nicklaus, P Russ, Maqbool A Siddiqui, H Ford, Hiroyuki Mitsuya, R Le, Eiichi N Kodama, Chris Meier, T Knispel, L Anderson, Joseph J Barchi, Victor E Marquez | Interactions of conformationally bias... | |
| 2000 | F S Shah, Kenneth A Curr, Monica E Hamburgh, M Parniak, Hiroyuki Mitsuya, J G Arnez, Vinayaka R Prasad | Differential influence of nucleoside ... | |
| 2000 | Kristel Van Laethem, J C Schmit, H Pelemans, Jan Balzarini, Myriam Witvrouw, María-Jesús Pérez-Pérez, María-José Camarasa, R M Esnouf, Stefano Aquaro, A Cenci, CF Perno, P Hermans, S Sprecher, L Ruiz, B Clotet, Eric Van Wijngaerden, M Van Ranst, J Desmyter, Erik De Clercq, A-M Vandamme | Presence of 2',5'-Bis-O-(tert-butyldi... | |
| 2000 | Bluma G Brenner, Mark A. Wainberg, H Salomon, D Rouleau, A Dascal, Bonnie Spira, Rafick-Pierre Sekaly, Brian Conway, Jean-Pierre Routy | Resistance to antiretroviral drugs in... | |
| 2000 | K K Weiss, S J Isaacs, N H Tran, Elinor T Adman, Baek Kim | Molecular architecture of the mutagen... | |
| 2000 | P Richard Harrigan, C Stone, P Griffin, I Nájera, Stuart Bloor, S Kemp, M Tisdale, Brendan A Larder | Resistance profile of the human immun... | |
| 2000 | Nicolas Sluis-Cremer, G I Dmitrienko, Jan Balzarini, María-José Camarasa, Michael A. Parniak | Human immunodeficiency virus type 1 r... | |
| 2000 | Michael A. Parniak, Nicolas Sluis-Cremer | Inhibitors of HIV-1 reverse transcrip... | |
| 2000 | Jingshan Ren, C Nichols, Louise E Bird, Tsuyoshi Fujiwara, H Sugimoto, David I Stuart, David K Stammers | Binding of the second generation non-... | |
| 2000 | S Najmudin, Marie L Coté, D Sun, S Yohannan, Sherwin P Montano, J Gu, Millie M Georgiadis | Crystal structures of an N-terminal f... | |
| 2000 | A J Brown, H M Precious, Jeannette M Whitcomb, J K Wong, M Quigg, Wei Huang, E S Daar, R T D'Aquila, P H Keiser, E Connick, Nicholas S Hellmann, Christos J Petropoulos, Douglas D Richman, S J Little | Reduced susceptibility of human immun... | |
| 2000 | Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak | Molecular mechanisms of HIV-1 resista... | |
| 2000 | Lawrence A Loeb, J I Mullins | Lethal mutagenesis of HIV by mutageni... | |
| 2000 | G J Latham, E Forgacs, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd | Vertical-scanning mutagenesis of a cr... | |
| 2000 | Mickael Rigourd, J M Lanchy, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann, Roland Marquet | Inhibition of the initiation of HIV-1... | |
| 2000 | A Khorchid, H Javanbakht, S Wise, R Halwani, Michael A. Parniak, Mark A. Wainberg, Lawrence Kleiman | Sequences within Pr160gag-pol affecti... | |
| 2000 | Dominique Arion, Nicolas Sluis-Cremer, Michael A. Parniak | Mechanism by which phosphonoformic ac... | |
| 2000 | Jingshan Ren, John Milton, Kurt L Weaver, Steven A Short, David I Stuart, David K Stammers | Structural basis for the resilience o... | |
| 2000 | Giuseppe Campiani, M Fabbrini, Elena Morelli, Vito Nacci, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, C Fracasso, S Caccia | Non-nucleoside HIV-1 reverse transcri... | |
| 2000 | L T Bacheler, E D Anton, P Kudish, D Baker, J Bunville, K Krakowski, L Bolling, M Aujay, X V Wang, D Ellis, M F Becker, A L Lasut, H J George, D R Spalding, G Hollis, K Abremski | Human immunodeficiency virus type 1 m... | |
| 2000 | Hong Qiang Gao, Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | The role of steric hindrance in 3TC r... | |
| 2000 | C de Mendoza, V Soriano, C Briones, O Gallego, P Barreiro, A Alvarez, J González-Lahoz | Emergence of zidovudine resistance in... | |
| 2000 | Peter R Meyer, Suzanne E Matsuura, Raymond F Schinazi, Antero G So, Walter A Scott | Differential removal of thymidine nuc... | |
| 2000 | H Pelemans, Robert Esnouf, Erik De Clercq, Jan Balzarini | Mutational analysis of trp-229 of hum... | |
| 2000 | Jan Balzarini, Erik De Clercq, A Carbonez, V Burt, Jörg-Peter Kleim | Long-term exposure of HIV type 1-infe... | |
| 2000 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Analysis of mutations at positions 11... | |
| 1999 | M Madrid, A Jacobo-Molina, Jianping Ding, Edward Arnold | Major subdomain rearrangement in HIV-... | |
| 1999 | Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Similarities and differences in the R... | |
| 1999 | Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | Action of a new mammalian DNA polymer... | |
| 1999 | Thomas A Steitz | DNA polymerases: structural diversity... | |
| 1999 | Lawrence A Loeb, J M Essigmann, F Kazazi, Jun Zhang, K D Rose, J I Mullins | Lethal mutagenesis of HIV with mutage... | |
| 1999 | Taurai Tasara, Mario Amacker, Ulrich Hübscher | Intramolecular chimeras of the p51 su... | |
| 1999 | Andreas Marx, M Spichty, Mario Amacker, U Schwitter, Ulrich Hübscher, Thomas A Bickle, Giovanni Maga, Bernd Giese | Probing interactions between HIV-1 re... | |
| 1999 | L L Furge, F Peter Guengerich | Explanation of pre-steady-state kinet... | |
| 1999 | Matthias Götte, G Maier, A M Onori, Luciano Cellai, Mark A. Wainberg, H Heumann | Temporal coordination between initiat... | |
| 1999 | Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari | Molecular basis for the enantioselect... | |
| 1999 | Y Goldgur, R Craigie, G H Cohen, Tsuyoshi Fujiwara, T Yoshinaga, T Fujishita, H Sugimoto, T Endo, H Murai, D R Davies | Structure of the HIV-1 integrase cata... | |
| 1999 | Paul L Boyer, J Lisziewicz, F Lori, Stephen H Hughes | Analysis of amino insertion mutations... | |
| 1999 | J Izopet, A Bicart-See, C Pasquier, K Sandres, E Bonnet, B Marchou, J Puel, P Massip | Mutations conferring resistance to zi... | |
| 1999 | M D Powell, William A Beard, Katarzyna Bebenek, K J Howard, Stuart F J Le Grice, Thomas A Darden, Thomas A Kunkel, Samuel H Wilson, J G Levin | Residues in the alphaH and alphaI hel... | |
| 1999 | S Cen, Yangxin Huang, A Khorchid, J L Darlix, Mark A. Wainberg, Lawrence Kleiman | The role of Pr55(gag) in the annealin... | |
| 1999 | J M de Muys, H Gourdeau, N Nguyen-Ba, D L Taylor, P S Ahmed, T Mansour, C Locas, N Richard, Mark A. Wainberg, R F Rando | Anti-human immunodeficiency virus typ... | |
| 1999 | P F Lin, C J González, B Griffith, G Friedland, V Calvez, F Ferchal, Raymond F Schinazi, D H Shepp, A B Ashraf, Mark A. Wainberg, V Soriano, John W Mellors, R J Colonno | Stavudine resistance: an update on su... | |
| 1999 | M E Arranz, J A Díaz, S T Ingate, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, S Vega | Synthesis and anti-HIV activity of 1,... | |
| 1999 | M Högberg, Christer Sahlberg, P Engelhardt, Rolf Noréen, J Kangasmetsä, N G Johansson, Bo Oberg, L Vrang, Haijiang Zhang, B L Sahlberg, Torsten Unge, S Lövgren, Kerstin Fridborg, K Bäckbro | Urea-PETT compounds as a new class of... | |
| 1999 | Baek Kim, J C Ayran, S G Sagar, Elinor T Adman, S M Fuller, N H Tran, J Horrigan | New human immunodeficiency virus, typ... | |
| 1999 | M Wisniewski, C Palaniappan, Z Fu, Stuart F J Le Grice, P Fay, Robert A Bambara | Mutations in the primer grip region o... | |
| 1999 | I Pellegrin, J Izopet, J Reynes, M Denayrolles, Brigitte Montes, J L Pellegrin, P Massip, J Puel, H Fleury, Michel Segondy | Emergence of zidovudine and multidrug... | |
| 1999 | D A Lewis, Katarzyna Bebenek, William A Beard, Samuel H Wilson, Thomas A Kunkel | Uniquely altered DNA replication fide... | |
| 1999 | Dominique Arion, Michael A. Parniak | HIV resistance to zidovudine: the rol... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Touching the heart of HIV-1 drug resi... | |
| 1999 | Giuseppe Campiani, Elena Morelli, M Fabbrini, Vito Nacci, Giovanni Greco, Ettore Novellino, Anna Ramunno, Giovanni Maga, Silvio Spadari, G Caliendo, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, A Nacca, S Caccia | Pyrrolobenzoxazepinone derivatives as... | |
| 1999 | T Szyperski, Matthias Götte, M Billeter, E Perola, Luciano Cellai, H Heumann, K Wüthrich | NMR structure of the chimeric hybrid ... | |
| 1999 | Myriam Witvrouw, Christophe Pannecouque, Erik De Clercq, E Fernández-Alvarez, J L Marco | Inhibition of human immunodeficiency ... | |
| 1999 | Matthias Götte, Xincang Li, Mark A. Wainberg | HIV-1 reverse transcription: a brief ... | |
| 1999 | J J de Jong, J Goudsmit, V V Lukashov, M E Hillebrand, E Baan, R Huismans, Sven A Danner, J H ten Veen, F de Wolf, Suzanne Jurriaans | Insertion of two amino acids combined... | |
| 1999 | N Richar, Yudong Quan, H Salomon, M Hsu, J Bedard, P Richard Harrigan, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of HIV... | |
| 1999 | Yudong Quan, Liwei Rong, Chen Liang, Mark A. Wainberg | Reverse transcriptase inhibitors can ... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Arthur D Clark, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Lamivudine (3TC) resistance in HIV-1 ... | |
| 1999 | Myriam Witvrouw, Christophe Pannecouque, Kristel Van Laethem, J Desmyter, Erik De Clercq, Anne-Mieke Vandamme | Activity of non-nucleoside reverse tr... | |
| 1999 | Neerja Kaushik, Kamalendra Singh, I Alluru, Mukund J Modak | Tyrosine 222, a member of the YXDD mo... | |
| 1999 | A Rakik, M Ait-Khaled, P Griffin, T A Thomas, M Tisdale, Jörg-Peter Kleim | A novel genotype encoding a single am... | |
| 1999 | Zucai Suo, S J Lippard, Kenneth A Johnson | Single d(GpG)/cis-diammineplatinum(II... | |
| 1999 | Sylvie Doublié, M R Sawaya, Tom Ellenberger | An open and closed case for all polym... | |
| 1999 | Alexandra Vaisman, Susan E Lim, S M Patrick, William C Copeland, David C Hinkle, J J Turchi, Stephen G Chaney | Effect of DNA polymerases and high mo... | |
| 1999 | Yudong Quan, Dimitrios Motakis, R Buckheit, Z Q Xu, M T Flavin, Michael A. Parniak, Mark A. Wainberg | Sensitivity and resistance to (+)-cal... | |
| 1999 | Jan Balzarini | Suppression of resistance to drugs ta... | |
| 1999 | Sonsoles Velázquez, V Tuñón, M L Jimeno, Cristina Chamorro, Erik De Clercq, Jan Balzarini, María-José Camarasa | Potential multifunctional inhibitors ... | |
| 1999 | Brendan A Larder, Stuart Bloor, S D Kemp, Kurt Hertogs, R L Desmet, V Miller, M Sturmer, Schlomo Staszewski, Jingshan Ren, David K Stammers, David I Stuart, Rudi Pauwels | A family of insertion mutations betwe... | |
| 1999 | Peter R Meyer, Suzanne E Matsuura, A M Mian, Antero G So, Walter A Scott | A mechanism of AZT resistance: an inc... | |
| 1999 | Joy Y Feng, Karen S Anderson | Mechanistic studies comparing the inc... | |
| 1999 | Mark A. Wainberg, Michael D Miller, Yudong Quan, H Salomon, A S Mulato, P D Lamy, Nicolas A Margot, K E Anton, J M Cherrington | In vitro selection and characterizati... | |
| 1999 | Michael D Miller, K E Anton, A S Mulato, P D Lamy, J M Cherrington | Human immunodeficiency virus type 1 e... | |
| 1999 | Andrew L Hopkins, Jingshan Ren, Hiromichi Tanaka, Masanori Baba, M Okamato, David I Stuart, David K Stammers | Design of MKC-442 (emivirine) analogu... | |
| 1999 | G Borkow, Dominique Arion, Mark A. Wainberg, Michael A. Parniak | The thiocarboxanilide nonnucleoside i... | |
| 1999 | H Rübsamen-Waigmann, E Huguenel, A Shah, A Paessens, H J Ruoff, H von Briesen, A Immelmann, U Dietrich, Mark A. Wainberg | Resistance mutations selected in vivo... | |
| 1999 | Z Gu, Mark A. Wainberg, N Nguyen-Ba, L L'Heureux, J M de Muys, T L Bowlin, R F Rando | Mechanism of action and in vitro acti... | |
| 1999 | H Idriss, S Kawa, Z Damuni, E B Thompson, Samuel H Wilson | HIV-1 reverse transcriptase is phosph... | |
| 1999 | Katarzyna Bebenek, J C Boyer, Thomas A Kunkel | The base substitution fidelity of HIV... | |
| 1999 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, David I Stuart, David K Stammers | Crystallographic analysis of the bind... | |
| 1999 | Junxing Shi, J J McAtee, S Schlueter Wirtz, P Tharnish, A Juodawlkis, Dennis C Liotta, Raymond F Schinazi | Synthesis and biological evaluation o... | |
| 1998 | H Salomon, Julio S G Montaner, A Belmonte, Mark A. Wainberg | Diminished HIV-1 sensitivity to stavu... | |
| 1998 | Mark Cushman, A Casimiro-Garcia, E Hejchman, J A Ruell, M Huang, C A Schaeffer, K Williamson, W G Rice, Robert W Buckheit | New alkenyldiarylmethanes with enhanc... | |
| 1998 | L M Demeter, P M Meehan, G Morse, M A Fischl, M Para, W Powderly, J Leedom, J Holden-Wiltse, C Greisberger, K Wood, J Timpone, L K Wathen, T Nevin, L Resnick, D H Batts, R C Reichman | Phase I study of atevirdine mesylate ... | |
| 1998 | Yudong Quan, P Inouye, Chen Liang, Liwei Rong, Matthias Götte, Mark A. Wainberg | Dominance of the E89G substitution in... | |
| 1998 | H J Einolf, N Schnetz-Boutaud, F Peter Guengerich | Steady-state and pre-steady-state kin... | |
| 1998 | M Nakayabu, S Miwa, Motoshi Suzuki, Shunji Izuta, G Sobue, Shonen Yoshida | Mismatched nucleotides may facilitate... | |
| 1998 | Jianping Ding, Kalyan Das, Y Hsiou, Stefan G Sarafianos, Arthur D Clark, A Jacobo-Molina, C Tantillo, Stephen H Hughes, Edward Arnold | Structure and functional implications... | |
| 1998 | Silvio Spadari, Giovanni Maga, A Verri, Federico Focher | Molecular basis for the antiviral and... | |
| 1998 | Michael D Miller, P D Lamy, M D Fuller, A S Mulato, Nicolas A Margot, T Cihlar, J M Cherrington | Human immunodeficiency virus type 1 r... | |
| 1998 | Andreas Marx, Mario Amacker, M Stucki, Ulrich Hübscher, Thomas A Bickle, Bernd Giese | 4'-Acylated thymidine 5'-triphosphate... | |
| 1998 | H Togashi, Yoshiyuki Mizushina, Masaharu Takemura, Fumio Sugawara, Hiroyuki Koshino, Y Esumi, J Uzawa, H Kumagai, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | 4-Hydroxy-17-methylincisterol, an inh... | |
| 1998 | Yoshiyuki Mizushina, L Hanashima, Tsuyoshi Yamaguchi, Masaharu Takemura, Fumio Sugawara, Mineo Saneyoshi, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | A mushroom fruiting body-inducing sub... | |
| 1998 | Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | Sulfoquinovosyldiacylglycerol, KM043,... | |
| 1998 | William A Beard, Katarzyna Bebenek, Thomas A Darden, Lin Li, Rajendra Prasad, Thomas A Kunkel, Samuel H Wilson | Vertical-scanning mutagenesis of a cr... | |
| 1998 | D V Nissley, Paul L Boyer, D J Garfinkel, Stephen H Hughes, J N Strathern | Hybrid Ty1/HIV-1 elements used to det... | |
| 1998 | Zucai Suo, Kenneth A Johnson | DNA secondary structure effects on DN... | |
| 1998 | I Choudhury, Jianhong Wang, A B Rabson, S Stein, S Pooyan, S Stein, M J Leibowitz | Inhibition of HIV-1 replication by a ... | |
| 1998 | Zucai Suo, Kenneth A Johnson | Selective inhibition of HIV-1 reverse... | |
| 1998 | Mario Amacker, Ulrich Hübscher | Chimeric HIV-1 and feline immunodefic... | |
| 1998 | M von Janta-Lipinski, B Costisella, H Ochs, Ulrich Hübscher, P Hafkemeyer, E Matthes | Newly synthesized L-enantiomers of 3'... | |
| 1998 | Paul L Boyer, Hong Qiang Gao, Stephen H Hughes | A mutation at position 190 of human i... | |
| 1998 | William C Drosopoulos, Lisa F Rezende, Mark A. Wainberg, Vinayaka R Prasad | Virtues of being faithful: can we lim... | |
| 1998 | Hong Qiang Gao, Paul L Boyer, Edward Arnold, Stephen H Hughes | Effects of mutations in the polymeras... | |
| 1998 | E Cherry, N Morin, Mark A. Wainberg | Effect of HIV constructs containing p... | |
| 1998 | Akitsu Ogawa, Takashi Murate, Shunji Izuta, Masaharu Takemura, Kyoji Furuta, Jun'ichi Kobayashi, T Kamikawa, Y Nimura, Shonen Yoshida | Sulfated glycoglycerolipid from archa... | |
| 1998 | E Cherry, Chen Liang, Liwei Rong, Yudong Quan, P Inouye, Xincang Li, N Morin, M Kotler, Mark A. Wainberg | Characterization of human immunodefic... | |
| 1998 | P Inouye, E Cherry, M Hsu, S Zolla-Pazner, Mark A. Wainberg | Neutralizing antibodies directed agai... | |
| 1998 | Yudong Quan, Z Gu, Xincang Li, Chen Liang, Michael A. Parniak, Mark A. Wainberg | Endogenous reverse transcriptase assa... | |
| 1998 | H Kwon, N Pelletier, C DeLuca, P Genin, S Cisternas, R Lin, Mark A. Wainberg, J Hiscott | Inducible expression of IkappaBalpha ... | |
| 1998 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, J Warren, Jan Balzarini, David I Stuart, David K Stammers | Crystal structures of HIV-1 reverse t... | |
| 1998 | S W Graves, Allison A Johnson, Kenneth A Johnson | Expression, purification, and initial... | Processivity,Kd,Vmax,All properties |
| 1998 | Cristina Chamorro, María-José Camarasa, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, Ana San Félix | An approach towards the synthesis of ... | |
| 1998 | Dominique Arion, Neerja Kaushik, Suzanne McCormick, G Borkow, Michael A. Parniak | Phenotypic mechanism of HIV-1 resista... | |
| 1998 | C Katlama, M A Valantin, S Matheron, A Coutellier, V Calvez, D Descamps, C Longuet, M Bonmarchand, R Tubiana, M De Sa, R Lancar, Henri Agut, F Brun-Vezinet, D Costagliola | Efficacy and tolerability of stavudin... | |
| 1998 | Bruno Canard, S R Sarfati, Charles C Richardson | Enhanced binding of azidothymidine-re... | |
| 1998 | Baek Kim, T R Hathaway, Lawrence A Loeb | Fidelity of mutant HIV-1 reverse tran... | |
| 1998 | Joachim Jaeger, Tobias Restle, Thomas A Steitz | The structure of HIV-1 reverse transc... | |
| 1998 | Peter R Meyer, Suzanne E Matsuura, Antero G So, Walter A Scott | Unblocking of chain-terminated primer... | |
| 1998 | J C Schmit, L Ruiz, L Stuyver, Kristel Van Laethem, I Vanderlinden, T Puig, R Rossau, J Desmyter, Erik De Clercq, B Clotet, A-M Vandamme | Comparison of the LiPA HIV-1 RT test,... | |
| 1998 | Erik De Clercq | New perspectives for the treatment of... | |
| 1998 | D Harris, Neerja Kaushik, P K Pandey, P N Yadav, V N Pandey | Functional analysis of amino acid res... | |
| 1998 | Hao Huang, R Chopra, G L Verdine, S C Harrison | Structure of a covalently trapped cat... | |
| 1998 | G Tachedjian, John W Mellors, H Bazmi, J Mills | Impaired fitness of foscarnet-resista... | |
| 1998 | Yudong Quan, Chen Liang, P Inouye, Mark A. Wainberg | Enhanced impairment of chain elongati... | |
| 1998 | Joseph A Vaccaro, Karen S Anderson | Implication of the tRNA initiation st... | |
| 1998 | M Wasner, Dominique Arion, G Borkow, A Noronha, A H Uddin, Michael A. Parniak, Masad J Damha | Physicochemical and biochemical prope... | |
| 1998 | C Tamalet, J Izopet, N Koch, J Fantini, N Yahi | Stable rearrangements of the beta3-be... | |
| 1998 | Monica E Hamburgh, William C Drosopoulos, Vinayaka R Prasad | The influence of 3TC-resistance mutat... | |
| 1998 | Y Hsiou, Kalyan Das, Jianping Ding, Arthur D Clark, Jörg-Peter Kleim, M Rösner, I Winkler, G Riess, Stephen H Hughes, Edward Arnold | Structures of Tyr188Leu mutant and wi... | |
| 1998 | F J Palella, K M Delaney, A C Moorman, M O Loveless, J Fuhrer, G A Satten, D J Aschman, S D Holmberg | Declining morbidity and mortality amo... | |
| 1998 | Sonsoles Velázquez, Cristina Chamorro, María-Jesús Pérez-Pérez, R Alvarez, M L Jimeno, A Martín-Domenech, C Pérez, Federico Gago, Erik De Clercq, Jan Balzarini, Ana San-Félix, María-José Camarasa | Abasic analogues of TSAO-T as the fir... | |
| 1998 | A Acel, B E Udashkin, Mark A. Wainberg, E A Faust | Efficient gap repair catalyzed in vit... | |
| 1998 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, E Yvonne Jones, I Kirby, J Keeling, C K Ross, Brendan A Larder, David I Stuart, David K Stammers | 3'-Azido-3'-deoxythymidine drug resis... | |
| 1998 | M A Winters, K L Coolley, Y A Girard, D J Levee, H Hamdan, R W Shafer, D A Katzenstein, T C Merigan | A 6-basepair insert in the reverse tr... | |
| 1998 | Erik De Clercq | The role of non-nucleoside reverse tr... | |
| 1998 | H Jonckheere, Myriam Witvrouw, Erik De Clercq, J Anné | Lamivudine resistance of HIV type 1 d... | |
| 1998 | Matthias Götte, G Maier, H J Gross, H Heumann | Localization of the active site of HI... | |
| 1998 | D Harris, P N Yadav, V N Pandey | Loss of polymerase activity due to Ty... | |
| 1998 | Kamalendra Singh, Mukund J Modak | A unified DNA- and dNTP-binding mode ... | |
| 1998 | Myriam Witvrouw, M E Arranz, Christophe Pannecouque, R Declercq, H Jonckheere, J C Schmit, A-M Vandamme, J A Diaz, S T Ingate, J Desmyter, Robert Esnouf, L Van Meervelt, S Vega, Jan Balzarini, Erik De Clercq | 1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,... | |
| 1998 | H Pelemans, R M Esnouf, Michael A. Parniak, A-M Vandamme, Erik De Clercq, Jan Balzarini | A proline-to-histidine substitution a... | |
| 1998 | Tsuyoshi Fujiwara, Akira Sato, M el-Farrash, S Miki, K Abe, Y Isaka, M Kodama, Y Wu, L B Chen, H Harada, H Sugimoto, Masami Hatanaka, Y Hinuma | S-1153 inhibits replication of known ... | |
| 1997 | R M Esnouf, Jingshan Ren, Andrew L Hopkins, C K Ross, E Yvonne Jones, David K Stammers, David I Stuart | Unique features in the structure of t... | |
| 1997 | Jan Balzarini, H Pelemans, G Riess, M Roesner, I Winkler, Erik De Clercq, Jörg-Peter Kleim | Zidovudine-resistant human immunodefi... | |
| 1997 | Jan Balzarini, Erik De Clercq, K Uberla | SIV/HIV-1 hybrid virus expressing the... | |
| 1997 | I V Safronov, N V Shcherbik, Svetlana N Khodyreva, V A Vlasov, M I Dobrikov, G V Shishkin, Olga I Lavrik | [New photoreactive N(4)-substituted d... | |
| 1997 | Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, Koen Andries, Robert W Buckheit, Richard H Smith | Molecular modeling of HIV-1 reverse t... | |
| 1997 | Neerja Kaushik, D Harris, N Rege, Mukund J Modak, P N Yadav, V N Pandey | Role of glutamine-151 of human immuno... | |
| 1997 | Thomas Roth, Marshall L Morningstar, Paul L Boyer, Stephen H Hughes, Robert W Buckheit, Christopher J Michejda | Synthesis and biological activity of ... | |
| 1997 | Stefano Aquaro, CF Perno, Emanuela Balestra, Jan Balzarini, A Cenci, M Francesconi, S Panti, F Serra, N Villani, Raffaele Caliò | Inhibition of replication of HIV in p... | |
| 1997 | Jörg-Peter Kleim, I Winkler, M Rösner, R Kirsch, H Rübsamen-Waigmann, A Paessens, G Riess | In vitro selection for different muta... | |
| 1997 | Y M Lin, H Anderson, M T Flavin, Y H Pai, E Mata-Greenwood, T Pengsuparp, J M Pezzuto, Raymond F Schinazi, Stephen H Hughes, F C Chen | In vitro anti-HIV activity of biflavo... | |
| 1997 | A De Antoni, A Foli, J Lisziewicz, F Lori | Mutations in the pol gene of human im... | |
| 1997 | M D Powell, M Ghosh, P S Jacques, K J Howard, Stuart F J Le Grice, J G Levin | Alanine-scanning mutations in the "pr... | |
| 1997 | Myriam Witvrouw, Jan Balzarini, Christophe Pannecouque, S Jhaumeer-Laulloo, J A Esté, Dominique Schols, Peter Cherepanov, J C Schmit, Zeger Debyser, A-M Vandamme, J Desmyter, S R Ramadas, Erik De Clercq | SRR-SB3, a disulfide-containing macro... | |
| 1997 | G Gao, M Orlova, Millie M Georgiadis, W A Hendrickson, S P Goff | Conferring RNA polymerase activity to... | |
| 1997 | T Rubinek, M Bakhanashvili, R Taube, O Avidan, A Hizi | The fidelity of 3' misinsertion and m... | |
| 1997 | E Forgacs, G Latham, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd | Probing structure/function relationsh... | |
| 1997 | Zucai Suo, Kenneth A Johnson | Effect of RNA secondary structure on ... | |
| 1997 | M A Winters, R W Shafer, R A Jellinger, G Mamtora, T Gingeras, T C Merigan | Human immunodeficiency virus type 1 r... | |
| 1997 | H Pelemans, Robert Esnouf, A Dunkler, Michael A. Parniak, A-M Vandamme, Anna Karlsson, Erik De Clercq, Jörg-Peter Kleim, Jan Balzarini | Characteristics of the Pro225His muta... | |
| 1997 | Robert W Buckheit, M J Snow, V Fliakas-Boltz, T L Kinjerski, J D Russell, L A Pallansch, W G Brouwer, S S Yang | Highly potent oxathiin carboxanilide ... | |
| 1997 | B P Burnett, Charles S McHenry | Posttranscriptional modification of r... | |
| 1997 | Zucai Suo, Kenneth A Johnson | RNA secondary structure switching dur... | |
| 1997 | Erik De Clercq | Development of resistance of human im... | |
| 1997 | Giovanni Maga, Mario Amacker, N Ruel, Ulrich Hübscher, Silvio Spadari | Resistance to nevirapine of HIV-1 rev... | |
| 1997 | Erik De Clercq | In search of a selective antiviral ch... | |
| 1997 | F Lori, A G Malykh, A Foli, R Maserati, A De Antoni, L Minoli, D Padrini, A Degli Antoni, E Barchi, H Jessen, Mark A. Wainberg, R C Gallo, J Lisziewicz | Combination of a drug targeting the c... | |
| 1997 | M Hsu, P Inouye, L Rezende, N Richard, Zhongjie Li, Vinayaka R Prasad, Mark A. Wainberg | Higher fidelity of RNA-dependent DNA ... | |
| 1997 | Mark A. Wainberg | Increased fidelity of drug-selected M... | |
| 1997 | J Mak, A Khorchid, Q Cao, Yangxin Huang, I Lowy, Michael A. Parniak, Vinayaka R Prasad, Mark A. Wainberg, Lawrence Kleiman | Effects of mutations in Pr160gag-pol ... | |
| 1997 | L L Furge, F Peter Guengerich | Analysis of nucleotide insertion and ... | |
| 1997 | Zucai Suo, Kenneth A Johnson | Effect of RNA secondary structure on ... | |
| 1997 | W Tong, C D Lu, S K Sharma, S Matsuura, Antero G So, Walter A Scott | Nucleotide-induced stable complex for... | |
| 1997 | Myriam Witvrouw, Erik De Clercq | Sulfated polysaccharides extracted fr... | |
| 1997 | Takayuki Ueno, Hiroyuki Mitsuya | Comparative enzymatic study of HIV-1 ... | |
| 1997 | C Palaniappan, M Wisniewski, P S Jacques, Stuart F J Le Grice, P J Fay, Robert A Bambara | Mutations within the primer grip regi... | |
| 1997 | J Barnard, G Borkow, Michael A. Parniak | The thiocarboxanilide nonnucleoside U... | |
| 1997 | Bruno Canard, R Sarfati, Charles C Richardson | Binding of RNA template to a complex ... | |
| 1997 | Jianping Ding, Stephen H Hughes, Edward Arnold | Protein-nucleic acid interactions and... | |
| 1997 | M Tanaka, R V Srinivas, Takayuki Ueno, M F Kavlick, F K Hui, A Fridland, J S Driscoll, Hiroyuki Mitsuya | In vitro induction of human immunodef... | |
| 1997 | Ashwini S Kamath-Loeb, A Hizi, Hironori Kasai, Lawrence A Loeb | Incorporation of the guanosine tripho... | |
| 1997 | A Hizi, Ashwini S Kamath-Loeb, K D Rose, Lawrence A Loeb | Mutagenesis by human immunodeficiency... | |
| 1997 | Mario Amacker, M Hottiger, R Mossi, Ulrich Hübscher | HIV-1 nucleocapsid protein and replic... | |
| 1997 | G Borkow, J Barnard, T M Nguyen, A Belmonte, Mark A. Wainberg, Michael A. Parniak | Chemical barriers to human immunodefi... | |
| 1997 | G Borkow, Ronald S Fletcher, J Barnard, Dominique Arion, Dimitrios Motakis, G I Dmitrienko, Michael A. Parniak | Inhibition of the ribonuclease H and ... | |
| 1997 | R Krebs, U Immendörfer, S H Thrall, B M Wöhrl, R S Goody | Single-step kinetics of HIV-1 reverse... | |
| 1997 | Chen Liang, Liwei Rong, N Morin, E Cherry, Yangxin Huang, Lawrence Kleiman, Mark A. Wainberg | The roles of the human immunodeficien... | |
| 1997 | S G Kerr, Karen S Anderson | Pre-steady-state kinetic characteriza... | |
| 1997 | G Borkow, Dominique Arion, A Noronha, M Scartozzi, Masad J Damha, Michael A. Parniak | Inhibitory potency of R-region specif... | |
| 1997 | Chen Liang, Xincang Li, Liwei Rong, P Inouye, Yudong Quan, Lawrence Kleiman, Mark A. Wainberg | The importance of the A-rich loop in ... | |
| 1997 | S Loya, Hong Qiang Gao, O Avidan, Paul L Boyer, Stephen H Hughes, A Hizi | Subunit-specific mutagenesis of the c... | |
| 1997 | Yoshiyuki Mizushina, Shonen Yoshida, Akio Matsukage, Kengo Sakaguchi | The inhibitory action of fatty acids ... | |
| 1997 | R M Esnouf, David I Stuart, Erik De Clercq, E Schwartz, Jan Balzarini | Models which explain the inhibition o... | |
| 1997 | H Hara, T Fujihashi, T Sakata, A Kaji, H Kaji | Tetrahydronaphthalene lignan compound... | |
| 1997 | W Keulen, N K Back, A van Wijk, Charles A B Boucher, Ben Berkhout | Initial appearance of the 184Ile vari... | |
| 1997 | M Tisdale, T Alnadaf, D Cousens | Combination of mutations in human imm... | |
| 1996 | J A Esté, K De Vreese, Myriam Witvrouw, J C Schmit, A-M Vandamme, J Anné, J Desmyter, G W Henson, G Bridger, Erik De Clercq | Antiviral activity of the bicyclam de... | |
| 1996 | Z Gu, Xincang Li, Yudong Quan, Michael A. Parniak, Mark A. Wainberg | Studies of neutralizing monoclonal an... | |
| 1996 | R A Spence, Karen S Anderson, Kenneth A Johnson | HIV-1 reverse transcriptase resistanc... | |
| 1996 | Jan Balzarini, W G Brouwer, D C Dao, E M Osika, Erik De Clercq | Identification of novel thiocarboxani... | |
| 1996 | V N Pandey, Neerja Kaushik, N Rege, Stefan G Sarafianos, P N Yadav, Mukund J Modak | Role of methionine 184 of human immun... | |
| 1996 | CF Perno, Emanuela Balestra, Stefano Aquaro, S Panti, A Cenci, G Lazzarino, B Tavazzi, D Di Pierro, Jan Balzarini, R Calio | Potent inhibition of human immunodefi... | |
| 1996 | Edward Arnold, Kalyan Das, Jianping Ding, P N Yadav, Y Hsiou, Paul L Boyer, Stephen H Hughes | Targeting HIV reverse transcriptase f... | |
| 1996 | Mark A. Wainberg, M Hsu, Z Gu, G Borkow, Michael A. Parniak | Effectiveness of 3TC in HIV clinical ... | |
| 1996 | H D Sun, S X Qiu, L Z Lin, Z Y Wang, Z W Lin, T Pengsuparp, J M Pezzuto, H H Fong, G A Cordell, N R Farnsworth | Nigranoic acid, a triterpenoid from S... | |
| 1996 | J M Cherrington, M D Fuller, A S Mulato, S J Allen, S C Kunder, M A Ussery, Z Lesnikowski, Raymond F Schinazi, J P Sommadossi, M S Chen | Comparative kinetic analyses of inter... | |
| 1996 | H Jonckheere, K De Vreese, Zeger Debyser, J Vandekerckhove, Jan Balzarini, J Desmyter, Erik De Clercq, J Anné | A two plasmid co-expression system in... | |
| 1996 | Jan Balzarini, O Wedgwood, J Kruining, H Pelemans, R Heijtink, Erik De Clercq, Christopher McGuigan | Anti-HIV and anti-HBV activity and re... | |
| 1996 | William C Drosopoulos, Vinayaka R Prasad | Increased polymerase fidelity of E89G... | |
| 1996 | Dominique Arion, Ronald S Fletcher, G Borkow, María-José Camarasa, Jan Balzarini, G I Dmitrienko, Michael A. Parniak | Differences in the inhibition of huma... | |
| 1996 | G Tachedjian, J Mellors, H Bazmi, C Birch, J Mills | Zidovudine resistance is suppressed b... | |
| 1996 | Jan Balzarini, H Pelemans, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson | Marked inhibitory activity of non-nuc... | |
| 1996 | A Foli, K M Sogocio, B Anderson, M Kavlick, M W Saville, Mark A. Wainberg, Z Gu, J M Cherrington, Hiroyuki Mitsuya, R Yarchoan | In vitro selection and molecular char... | |
| 1996 | Ronald S Fletcher, G Holleschak, Eva Nagy, Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak | Single-step purification of recombina... | |
| 1996 | Mark A. Wainberg, L Lewis, H Salomon, Z Gu, A Keller, Nick Cammack, J Goldsmith, J Church, Bonnie Spira, S Wheeler, P Pizzo | Resistance to (-)-2',3'-dideoxy-3'-th... | |
| 1996 | F Soler, C Poujade, M Evers, J C Carry, Y Hénin, Anne Bousseau, T Huet, Rudi Pauwels, Erik De Clercq, J F Mayaux, J B Le Pecq, N Dereu | Betulinic acid derivatives: a new cla... | |
| 1996 | Charles A B Boucher, W Keulen, T van Bommel, Monique Nijhuis, D de Jong, M D de Jong, P Schipper, N K Back | Human immunodeficiency virus type 1 d... | |
| 1996 | Xincang Li, Yudong Quan, E.J. Arts, Zhongjie Li, Bradley D Preston, H de Rocquigny, Bernard P Roques, J L Darlix, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg | Human immunodeficiency virus Type 1 n... | |
| 1996 | Baek Kim, T R Hathaway, Lawrence A Loeb | Human immunodeficiency virus reverse ... | |
| 1996 | A K Iversen, R W Shafer, K Wehrly, M A Winters, J I Mullins, B Chesebro, T C Merigan | Multidrug-resistant human immunodefic... | |
| 1996 | Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Stephen H Hughes, Edward Arnold | Structure of unliganded HIV-1 reverse... | |
| 1996 | J M Cherrington, A S Mulato, M D Fuller, M S Chen | Novel mutation (K70E) in human immuno... | |
| 1996 | Mark A. Wainberg, William C Drosopoulos, H Salomon, M Hsu, G Borkow, M Parniak, Z Gu, Q Song, J Manne, S Islam, G Castriota, Vinayaka R Prasad | Enhanced fidelity of 3TC-selected mut... | |
| 1996 | B M Moore, Ke Li, Michael B Doughty | Deoxyadenosine-based DNA polymerase p... | |
| 1996 | Neerja Kaushik, N Rege, P N Yadav, Stefan G Sarafianos, Mukund J Modak, V N Pandey | Biochemical analysis of catalytically... | |
| 1996 | William A Beard, Dana T Minnick, C L Wade, Rajendra Prasad, R L Won, A Kumar, Thomas A Kunkel, Samuel H Wilson | Role of the "helix clamp" in HIV-1 re... | |
| 1996 | L M Mansky | Forward mutation rate of human immuno... | |
| 1996 | M G Davis, J E Wilson, N A VanDraanen, W H Miller, George A Freeman, S M Daluge, F L Boyd, A E Aulabaugh, George R Painter, Lawrence R Boone | DNA polymerase activity of hepatitis ... | |
| 1996 | Andrew L Hopkins, Jingshan Ren, R M Esnouf, B E Willcox, E Yvonne Jones, C Ross, T Miyasaka, R T Walker, Hiromichi Tanaka, David K Stammers, David I Stuart | Complexes of HIV-1 reverse transcript... | |
| 1996 | A M Martín-Hernández, Esteban Domingo, L Menéndez-Arias | Human immunodeficiency virus type 1 r... | |
| 1996 | Zeger Debyser, Erik De Clercq | Chemical crosslinking of the subunits... | |
| 1996 | Zhongjie Li, A Shalom, Yangxin Huang, J Mak, E Arts, Mark A. Wainberg, Lawrence Kleiman | Multiple forms of tRNA(Lys3) in HIV-1. | |
| 1996 | M Evers, C Poujade, F Soler, Y Ribeill, C James, Y Lelièvre, J C Gueguen, D Reisdorf, I Morize, Rudi Pauwels, Erik De Clercq, Y Hénin, Anne Bousseau, J F Mayaux, J B Le Pecq, N Dereu | Betulinic acid derivatives: a new cla... | |
| 1996 | Rudi Pauwels, Erik De Clercq | Development of vaginal microbicides f... | |
| 1996 | Yudong Quan, Z Gu, Xincang Li, Zhongjie Li, C D Morrow, Mark A. Wainberg | Endogenous reverse transcription assa... | |
| 1996 | Stefan G Sarafianos, U Kortz, M T Pope, Mukund J Modak | Mechanism of polyoxometalate-mediated... | |
| 1996 | J Ji, N J Clegg, K R Peterson, A L Jackson, C D Laird, Lawrence A Loeb | In vitro expansion of GGC:GCC repeats... | |
| 1996 | J E Wilson, A Aulabaugh, B Caligan, S McPherson, J K Wakefield, S Jablonski, C D Morrow, J E Reardon, Phillip A Furman | Human immunodeficiency virus type-1 r... | |
| 1996 | N K Back, Monique Nijhuis, W Keulen, Charles A B Boucher, B O Oude Essink, A B van Kuilenburg, A H van Gennip, Ben Berkhout | Reduced replication of 3TC-resistant ... | |
| 1996 | R A Olmsted, D E Slade, L A Kopta, S M Poppe, T J Poel, S W Newport, K B Rank, C Biles, R A Morge, T J Dueweke, Y Yagi, D L Romero, R C Thomas, S K Sharma, W G Tarpley | (Alkylamino) piperidine bis(heteroary... | |
| 1996 | D Bellarosa, G Antonelli, F Bambacioni, D Giannotti, G Viti, R Nannicini, A Giachetti, F Dianzani, Myriam Witvrouw, Rudi Pauwels, J Desmyter, Erik De Clercq | New arylpyrido-diazepine and -thiodia... | |
| 1996 | L Hong, A Treharne, J A Hartsuck, S Foundling, J Tang | Crystal structures of complexes of a ... | |
| 1996 | D L Winslow, S Garber, C Reid, H Scarnati, D Baker, M M Rayner, E D Anton | Selection conditions affect the evolu... | |
| 1996 | G Yang, Q Song, M Charles, William C Drosopoulos, Edward Arnold, Vinayaka R Prasad | Use of chimeric human immunodeficienc... | |
| 1996 | Michael J Lutz, H A Held, M Hottiger, Ulrich Hübscher, Steven A Benner | Differential discrimination of DNA po... | |
| 1996 | Yangxin Huang, A Shalom, Zhongjie Li, Jiong Wang, J Mak, Mark A. Wainberg, Lawrence Kleiman | Effects of modifying the tRNA(3Lys) a... | |
| 1996 | S Ingate, Erik De Clercq, Jan Balzarini, María-José Camarasa | Novel L-lyxo and 5'-deoxy-5'-modified... | |
| 1996 | Dominique Arion, R Harada, Xincang Li, Mark A. Wainberg, Michael A. Parniak | HIV-1 reverse transcriptase shows no ... | |
| 1996 | M Hottiger, Ulrich Hübscher | Human Immunodeficiency Virus type 1 r... | |
| 1996 | Erik De Clercq | Chemotherapy of human immunodeficienc... | |
| 1996 | P Richard Harrigan, I Kinghorn, Stuart Bloor, S D Kemp, I Nájera, A Kohli, Brendan A Larder | Significance of amino acid variation ... | |
| 1996 | Olga I Lavrik, Rajendra Prasad, William A Beard, I V Safronov, M I Dobrikov, Deepak K Srivastava, G V Shishkin, T G Wood, Samuel H Wilson | dNTP binding to HIV-1 reverse transcr... | |
| 1996 | Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak | The K65R mutation confers increased D... | RT,Cloned or native,Full length or truncated,Extension from RNA primer,All properties |
| 1996 | E.J. Arts, J P Marois, Z Gu, Stuart F J Le Grice, Mark A. Wainberg | Effects of 3'-deoxynucleoside 5'-trip... | |
| 1996 | D J Hooker, G Tachedjian, A E Solomon, A D Gurusinghe, S Land, C Birch, J L Anderson, B M Roy, Edward Arnold, N J Deacon | An in vivo mutation from leucine to t... | |
| 1996 | T Pengsuparp, M Serit, Stephen H Hughes, D D Soejarto, J M Pezzuto | Specific inhibition of human immunode... | |
| 1996 | Kalyan Das, Jianping Ding, Y Hsiou, Arthur D Clark, H Moereels, Luc Koymans, Koen Andries, Rudi Pauwels, Paul A J Janssen, Paul L Boyer, Patrick K Clark, Richard H Smith, Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Edward Arnold | Crystal structures of 8-Cl and 9-Cl T... | |
| 1996 | Jörg-Peter Kleim, M Rösner, I Winkler, A Paessens, R Kirsch, Y Hsiou, Edward Arnold, G Riess | Selective pressure of a quinoxaline n... | |
| 1995 | Jan Balzarini, M Weeger, María-José Camarasa, Erik De Clercq, K Uberla | Sensitivity/resistance profile of a s... | |
| 1995 | Sonsoles Velázquez, R Alvarez, Ana San-Félix, M L Jimeno, Erik De Clercq, Jan Balzarini, María-José Camarasa | Synthesis and anti-HIV activity of [A... | |
| 1995 | Y Törnevik, B Ullman, Jan Balzarini, B Wahren, Staffan Eriksson | Cytotoxicity of 3'-azido-3'-deoxythym... | |
| 1995 | Jan Balzarini | Novel concepts in the treatment of hu... | |
| 1995 | Jan Balzarini, Masanori Baba, Erik De Clercq | Differential activities of 1-[(2-hydr... | |
| 1995 | Jianping Ding, Kalyan Das, H Moereels, Luc Koymans, Koen Andries, Paul A J Janssen, Stephen H Hughes, Edward Arnold | Structure of HIV-1 RT/TIBO R 86183 co... | |
| 1995 | Z Gu, E.J. Arts, Michael A. Parniak, Mark A. Wainberg | Mutated K65R recombinant reverse tran... | |
| 1995 | Takayuki Ueno, T Shirasaka, Hiroyuki Mitsuya | Enzymatic characterization of human i... | |
| 1995 | Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak | Site-directed mutagenesis of arginine... | |
| 1995 | Mark A. Wainberg, Z Gu, H Salomon, E.J. Arts, Lawrence Kleiman, Michael A. Parniak, N Morin | [Molecular basis and clinical signifi... | |
| 1995 | Ronald S Fletcher, Dominique Arion, G Borkow, Mark A. Wainberg, G I Dmitrienko, Michael A. Parniak | Synergistic inhibition of HIV-1 rever... | |
| 1995 | M I Anazodo, Mark A. Wainberg, A D Friesen, J A Wright | Sequence-specific inhibition of gene ... | |
| 1995 | K Rittinger, G Divita, R S Goody | Human immunodeficiency virus reverse ... | |
| 1995 | D W Rodgers, S J Gamblin, B A Harris, S Ray, J S Culp, B Hellmig, D J Woolf, C Debouck, S C Harrison | The structure of unliganded reverse t... | |
| 1995 | Rob Schuurman, Monique Nijhuis, R van Leeuwen, P Schipper, D de Jong, P Collis, Sven A Danner, J Mulder, C Loveday, C Christopherson | Rapid changes in human immunodeficien... | |
| 1995 | Ronald S Fletcher, K Syed, S Mithani, G I Dmitrienko, Michael A. Parniak | Carboxanilide derivative non-nucleosi... | |
| 1995 | Brendan A Larder, S D Kemp, P Richard Harrigan | Potential mechanism for sustained ant... | |
| 1995 | M Hottiger, K Gramatikoff, O Georgiev, C Chaponnier, W Schaffner, Ulrich Hübscher | The large subunit of HIV-1 reverse tr... | |
| 1995 | P H Patel, A Jacobo-Molina, Jianping Ding, C Tantillo, Art D Clark, R Raag, R G Nanni, Stephen H Hughes, Edward Arnold | Insights into DNA polymerization mech... | |
| 1995 | B M Wöhrl, C Tantillo, Edward Arnold, Stuart F J Le Grice | An expanded model of replicating huma... | |
| 1995 | M Ghosh, K J Howard, Craig E Cameron, Stephen J Benkovic, Stephen H Hughes, Stuart F J Le Grice | Truncating alpha-helix E' of p66 huma... | |
| 1995 | Edward Arnold, Jianping Ding, Stephen H Hughes, Z Hostomsky | Structures of DNA and RNA polymerases... | |
| 1995 | Jianping Ding, Kalyan Das, C Tantillo, Weiming Zhang, Arthur D Clark, S Jessen, Xiaoqing Lu, Y Hsiou, A Jacobo-Molina, Koen Andries | Structure of HIV-1 reverse transcript... | |
| 1995 | T Shirasaka, M F Kavlick, Takayuki Ueno, W Y Gao, E Kojima, M L Alcaide, S Chokekijchai, B M Roy, Edward Arnold, R Yarchoan | Emergence of human immunodeficiency v... | |
| 1995 | Silvio Spadari, Giovanni Maga, A Verri, A Bendiscioli, L Tondelli, M Capobianco, F Colonna, A Garbesi, Federico Focher | Lack of stereospecificity of some cel... | |
| 1995 | P N Yadav, J S Yadav, Mukund J Modak | Nucleoside drug resistance in HIV-1 r... | |
| 1995 | Erik De Clercq, Jan Balzarini | Knocking out human immunodeficiency v... | |
| 1995 | Jan Balzarini, W G Brouwer, E E Felauer, Erik De Clercq, Anna Karlsson | Activity of various thiocarboxanilide... | |
| 1995 | Marilyn B Kroeger Smith, C A Rouzer, L A Taneyhill, N A Smith, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, H Moereels, Luc Koymans, Edward Arnold | Molecular modeling studies of HIV-1 r... | |
| 1995 | Jingshan Ren, R Esnouf, E Garman, D Somers, C Ross, I Kirby, J Keeling, G Darby, Y Jones, David I Stuart | High resolution structures of HIV-1 R... | |
| 1995 | Baek Kim, Lawrence A Loeb | A screen in Escherichia coli for nucl... | |
| 1995 | J Horlacher, M Hottiger, Vladimir N Podust, Ulrich Hübscher, Steven A Benner | Recognition by viral and cellular DNA... | |
| 1995 | Mark A. Wainberg, Z Gu | Targeting HIV reverse transcriptase i... | |
| 1995 | G Tachedjian, D J Hooker, A D Gurusinghe, H Bazmi, N J Deacon, J Mellors, C Birch, J Mills | Characterisation of foscarnet-resista... | |
| 1995 | L M Mansky, H M Temin | Lower in vivo mutation rate of human ... | |
| 1995 | Robert W Buckheit, T L Kinjerski, V Fliakas-Boltz, J D Russell, T L Stup, L A Pallansch, W G Brouwer, D C Dao, W A Harrison, R J Schultz | Structure-activity and cross-resistan... | |
| 1995 | Z Gu, Yudong Quan, Zhongjie Li, E.J. Arts, Mark A. Wainberg | Effects of non-nucleoside inhibitors ... | |
| 1995 | M I Anazodo, H Salomon, A D Friesen, Mark A. Wainberg, J A Wright | Antiviral activity and protection of ... | |
| 1995 | John W Mellors, Holly Z Bazmi, Raymond F Schinazi, B M Roy, Y Hsiou, Edward Arnold, J Weir, D L Mayers | Novel mutations in reverse transcript... | |
| 1995 | E.J. Arts, Zhongjie Li, Mark A. Wainberg | Analysis of Primer Extension and the ... | |
| 1995 | V McKiel, Z Gu, Mark A. Wainberg, J Hiscott | Inhibition of human immunodeficiency ... | |
| 1995 | M Sala, S Wain-Hobson, F Schaeffer | Human immunodeficiency virus type 1 r... | |
| 1995 | R J Germinario, T DeSantis, Mark A. Wainberg | Insulin-like growth factor 1 and insu... | |
| 1995 | Matthias Götte, S Fackler, T Hermann, E Perola, Luciano Cellai, H J Gross, Stuart F J Le Grice, H Heumann | HIV-1 reverse transcriptase-associate... | |
| 1995 | S D Young, S F Britcher, L O Tran, L S Payne, W C Lumma, T A Lyle, J R Huff, P S Anderson, David B Olsen, Steven S Carroll | L-743, 726 (DMP-266): a novel, highly... | |
| 1995 | Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak | Glutamine 151 participates in the sub... | |
| 1995 | Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari | Stereospecificity of human DNA polyme... | |
| 1995 | Katarzyna Bebenek, William A Beard, J R Casas-Finet, H R Kim, Thomas A Darden, Samuel H Wilson, Thomas A Kunkel | Reduced frameshift fidelity and proce... | |
| 1995 | M Jaju, William A Beard, Samuel H Wilson | Human immunodeficiency virus type 1 r... | |
| 1995 | Robert W Buckheit, V Fliakas-Boltz, S Yeagy-Bargo, O Weislow, D L Mayers, Paul L Boyer, Stephen H Hughes, B C Pan, S H Chu, J P Bader | Resistance to 1-[(2-hydroxyethoxy)met... | |
| 1995 | Haijiang Zhang, L Vrang, K Bäckbro, P Lind, Christer Sahlberg, Torsten Unge, Bo Oberg | Inhibition of human immunodeficiency ... | |
| 1995 | Jörg-Peter Kleim, R Bender, R Kirsch, C Meichsner, A Paessens, M Rösner, H Rübsamen-Waigmann, R Kaiser, M Wichers, K E Schneweis | Preclinical evaluation of HBY 097, a ... | |
| 1995 | Jan Balzarini, María-Jesús Pérez-Pérez, S Vélazquez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson | Suppression of the breakthrough of hu... | |
| 1995 | Hongxing Zhang, Yang Zhang, T Spicer, D Henrard, B J Poiesz | Nascent human immunodeficiency virus ... | |
| 1995 | R A Spence, W M Kati, Karen S Anderson, Kenneth A Johnson | Mechanism of inhibition of HIV-1 reve... | |
| 1995 | N M Gray, C L Marr, C R Penn, J M Cameron, R C Bethell | The intracellular phosphorylation of ... | |
| 1995 | Katarzyna Bebenek, Thomas A Kunkel | Analyzing fidelity of DNA polymerases. | Frameshift Error Rate,Overall Error Rate,All properties |
| 1995 | Baek Kim, Lawrence A Loeb | Human immunodeficiency virus reverse ... | |
| 1995 | R Esnouf, Jingshan Ren, C Ross, Y Jones, D Stammers, David I Stuart | Mechanism of inhibition of HIV-1 reve... | |
| 1995 | R R Vyas, A K Basu | DNA polymerase action on an oligonucl... | |
| 1995 | Jingshan Ren, R Esnouf, A Hopkins, C Ross, Y Jones, D Stammers, David I Stuart | The structure of HIV-1 reverse transc... | |
| 1994 | Paul L Boyer, Andrea L Ferris, Patrick K Clark, J Whitmer, P Frank, C Tantillo, Edward Arnold, Stephen H Hughes | Mutational analysis of the fingers an... | |
| 1994 | Myron F Goodman, H Cai, Linda B Bloom, R Eritja | Nucleotide insertion and primer exten... | |
| 1994 | S Loya, M Bakhanashvili, R Tal, Stephen H Hughes, Paul L Boyer, A Hizi | Enzymatic properties of two mutants o... | |
| 1994 | Douglas D Richman, D Havlir, J Corbeil, D Looney, C Ignacio, S A Spector, J Sullivan, S Cheeseman, K Barringer, D Pauletti | Nevirapine resistance mutations of hu... | |
| 1994 | T Rubinek, S Loya, M Shaharabany, Stephen H Hughes, Patrick K Clark, A Hizi | The catalytic properties of the rever... | |
| 1994 | S Zinnen, J C Hsieh, P Modrich | Misincorporation and mispaired primer... | |
| 1994 | Torsten Unge, S Knight, R Bhikhabhai, S Lövgren, Z Dauter, K Wilson, B Strandberg | 2.2 A resolution structure of the ami... | |
| 1994 | V W Byrnes, E A Emini, W A Schleif, J H Condra, C L Schneider, W J Long, J A Wolfgang, D J Graham, L Gotlib, A J Schlabach | Susceptibilities of human immunodefic... | |
| 1994 | A-M Vandamme, Zeger Debyser, Rudi Pauwels, K De Vreese, P Goubau, M Youle, B Gazzard, P A Stoffels, G F Cauwenbergh, J Anne | Characterization of HIV-1 strains iso... | |
| 1994 | S V Doronin, M I Dobrikov, M Buckle, P Roux, H Buc, Olga I Lavrik | Affinity modification of human immuno... | |
| 1994 | Z Gu, Q Gao, H Fang, Michael A. Parniak, Bluma G Brenner, Mark A. Wainberg | Identification of novel mutations tha... | |
| 1994 | E.J. Arts, Xincang Li, Z Gu, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg | Comparison of deoxyoligonucleotide an... | |
| 1994 | Z Gu, Ronald S Fletcher, E.J. Arts, Mark A. Wainberg, Michael A. Parniak | The K65R mutant reverse transcriptase... | |
| 1994 | M Smith, H Salomon, Mark A. Wainberg | Development and significance of nucle... | |
| 1994 | I Kang, Jing-Houng Wang | Design of structure-based reverse tra... | |
| 1994 | M H Nguyen, Raymond F Schinazi, C Shi, N M Goudgaon, P M McKenna, John W Mellors | Resistance of human immunodeficiency ... | |
| 1994 | M Hottiger, Vladimir N Podust, R L Thimmig, C McHenry, Ulrich Hübscher | Strand displacement activity of the h... | |
| 1994 | P N Yadav, J S Yadav, Edward Arnold, Mukund J Modak | A computer-assisted analysis of conse... | |
| 1994 | H Pelletier, M R Sawaya, A Kumar, Samuel H Wilson, J Kraut | Structures of ternary complexes of ra... | |
| 1994 | M A Fisher, P N Yadav, J Yadav, D Kristol, Edward Arnold, Mukund J Modak | Identification of a pharmacophore for... | |
| 1994 | William A Beard, Samuel H Wilson | Site-directed mutagenesis of HIV reve... | |
| 1994 | H Jonckheere, J M Taymans, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, J Desmyter, Erik De Clercq, J Anné | Resistance of HIV-1 reverse transcrip... | |
| 1994 | M R Sawaya, H Pelletier, A Kumar, Samuel H Wilson, J Kraut | Crystal structure of rat DNA polymera... | |
| 1994 | Jan Balzarini, Anna Karlsson, V V Sardana, E A Emini, María-José Camarasa, Erik De Clercq | Human immunodeficiency virus 1 (HIV-1... | |
| 1994 | Jan Balzarini, Anna Karlsson, C Meichsner, A Paessens, G Riess, Erik De Clercq, Jörg-Peter Kleim | Resistance pattern of human immunodef... | |
| 1994 | G Gosselin, Raymond F Schinazi, J P Sommadossi, C Mathé, M C Bergogne, A M Aubertin, A Kirn, J L Imbach | Anti-human immunodeficiency virus act... | |
| 1994 | M D Delahunty, Samuel H Wilson, R L Karpel | Studies on primer binding of HIV-1 re... | |
| 1994 | Paul L Boyer, Jianping Ding, Edward Arnold, Stephen H Hughes | Subunit specificity of mutations that... | |
| 1994 | S J Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, A J Chirino, J M Friedman, P A Rice, Thomas A Steitz | Structure of the binding site for non... | |
| 1994 | T Hermann, T Meier, Matthias Götte, H Heumann | The 'helix clamp' in HIV-1 reverse tr... | |
| 1994 | Paul L Boyer, C Tantillo, A Jacobo-Molina, R G Nanni, Jianping Ding, Edward Arnold, Stephen H Hughes | Sensitivity of wild-type human immuno... | |
| 1994 | Erik De Clercq | HIV resistance to reverse transcripta... | |
| 1994 | Erik De Clercq | How to overcome resistance of HIV-1 t... | |
| 1994 | L Mercure, B J Brenner, D Phaneuf, C Tsoukas, Mark A. Wainberg | Effect of 3'-azido-3'-deoxythymidine ... | |
| 1994 | J Ji, Lawrence A Loeb | Fidelity of HIV-1 reverse transcripta... | |
| 1994 | Jan Balzarini, Jörg-Peter Kleim, G Riess, María-José Camarasa, Erik De Clercq, Anna Karlsson | Sensitivity of (138 Glu-->Lys) mutate... | |
| 1994 | P S Jacques, B M Wöhrl, M Ottmann, J L Darlix, Stuart F J Le Grice | Mutating the "primer grip" of p66 HIV... | |
| 1994 | E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg | DNA found in human immunodeficiency v... | |
| 1994 | Masanori Baba, S Shigeta, S Yuasa, H Takashima, K Sekiya, M Ubasawa, Hiromichi Tanaka, T Miyasaka, R T Walker, Erik De Clercq | Preclinical evaluation of MKC-442, a ... | |
| 1994 | E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg | Mature reverse transcriptase (p66/p51... | |
| 1994 | Jianping Ding, A Jacobo-Molina, C Tantillo, Xiaoqing Lu, R G Nanni, Edward Arnold | Buried surface analysis of HIV-1 reve... | |
| 1994 | J Mak, M Jiang, Mark A. Wainberg, M L Hammarskjöld, D Rekosh, Lawrence Kleiman | Role of Pr160gag-pol in mediating the... | |
| 1994 | Erik De Clercq | New developments in the chemotherapy ... | |
| 1994 | J Ji, Jean-Sébastien Hoffmann, L Loeb | Mutagenicity and pausing of HIV rever... | |
| 1994 | C Tantillo, Jianping Ding, A Jacobo-Molina, R G Nanni, Paul L Boyer, Stephen H Hughes, Rudi Pauwels, Koen Andries, Paul A J Janssen, Edward Arnold | Locations of anti-AIDS drug binding s... | |
| 1994 | Rudi Pauwels, Koen Andries, Zeger Debyser, Michael J Kukla, Dominique Schols, H J Breslin, R Woestenborghs, J Desmyter, M A Janssen, Erik De Clercq | New tetrahydroimidazo[4,5,1-jk][1,4]-... | |
| 1994 | A Okruszek, M Olesiak, Jan Balzarini | The synthesis of nucleoside 5'-O-(1,1... | |
| 1994 | J Jäger, S J Smerdon, Jianhong Wang, D C Boisvert, Thomas A Steitz | Comparison of three different crystal... | |
| 1994 | S F Lacey, Brendan A Larder | Novel mutation (V75T) in human immuno... | |
| 1993 | Jan Balzarini, Anna Karlsson, A-M Vandamme, María-Jesús Pérez-Pérez, Haijiang Zhang, L Vrang, Bo Oberg, K Bäckbro, Torsten Unge, Ana San-Félix | Human immunodeficiency virus type 1 (... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, L Vrang, J Walbers, Haijiang Zhang, Bo Oberg, A-M Vandamme, María-José Camarasa, Erik De Clercq | HIV-1-specific reverse transcriptase ... | |
| 1993 | Kristin A Eckert, Thomas A Kunkel | Fidelity of DNA synthesis catalyzed b... | Cloned or native,Full length or truncated,Specific Activity,3-5' exo,Nucleotide Substitution Rate,All properties |
| 1993 | J Abbotts, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson | Mechanism of HIV-1 reverse transcript... | |
| 1993 | Jörg-Peter Kleim, R Bender, U M Billhardt, C Meichsner, G Riess, M Rösner, I Winkler, A Paessens | Activity of a novel quinoxaline deriv... | |
| 1993 | R L Thimmig, Charles S McHenry | Human immunodeficiency virus reverse ... | |
| 1993 | W Y Gao, A Cara, R C Gallo, F Lori | Low levels of deoxynucleotides in per... | |
| 1993 | John W Mellors, G J Im, Enzo Tramontano, S R Winkler, D J Medina, Ginger E Dutschman, Holly Z Bazmi, G Piras, C J Gonzalez, Yung-Chi Cheng | A single conservative amino acid subs... | |
| 1993 | A Kumar, H R Kim, Robert W Sobol, S P Becerra, B J Lee, D L Hatfield, R J Suhadolnik, Samuel H Wilson | Mapping of nucleic acid binding in pr... | |
| 1993 | J L Martin, J E Wilson, R L Haynes, Phillip A Furman | Mechanism of resistance of human immu... | |
| 1993 | S P Becerra, A Kumar, Samuel H Wilson | Expression of polypeptides of human i... | |
| 1993 | A Jacobo-Molina, Jianping Ding, R G Nanni, Arthur D Clark, Xiaoqing Lu, C Tantillo, R L Williams, G Kamer, Andrea L Ferris, Patrick K Clark | Crystal structure of human immunodefi... | |
| 1993 | M S Chen, R T Suttmann, E Papp, P D Cannon, M J McRoberts, C Bach, William C Copeland, Teresa S-F Wang | Selective action of 4'-azidothymidine... | |
| 1993 | M Tisdale, S D Kemp, N R Parry, Brendan A Larder | Rapid in vitro selection of human imm... | |
| 1993 | Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors | Characterization of human immunodefic... | |
| 1993 | G T Tan, A Wickramasinghe, S Verma, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan | Sulfonic acid polymers are potent inh... | |
| 1993 | H Cai, Linda B Bloom, R Eritja, Myron F Goodman | Kinetics of deoxyribonucleotide inser... | |
| 1993 | J C Hsieh, S Zinnen, P Modrich | Kinetic mechanism of the DNA-dependen... | |
| 1993 | Erik De Clercq | HIV-1-specific RT inhibitors: highly ... | |
| 1993 | Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg | The same mutation that encodes low-le... | |
| 1993 | Jan Balzarini, Anna Karlsson, Erik De Clercq | Human immunodeficiency virus type 1 d... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, W G Tarpley, Erik De Clercq | Treatment of human immunodeficiency v... | |
| 1993 | S Kawa, A Kumar, J S Smith, S P Becerra, William A Beard, Samuel H Wilson, E B Thompson | Expression and purification of the HI... | |
| 1993 | S St Luce, E Arts, R Geleziunas, S Bour, Mark A. Wainberg | Infection of human monocyte-derived m... | |
| 1993 | Johan Neyts, F Stals, C Bruggeman, Erik De Clercq | Activity of the anti-HIV agent 9-(2-p... | |
| 1993 | R Goel, William A Beard, A Kumar, J R Casas-Finet, M P Strub, S J Stahl, M S Lewis, Katarzyna Bebenek, S P Becerra, Thomas A Kunkel | Structure/function studies of HIV-1(1... | |
| 1993 | Mark A. Wainberg, Z Gu, Q Gao, E Arts, R Geleziunas, S Bour, R Beaulieu, C Tsoukas, J Singer, J Montaner | Clinical correlates and molecular bas... | |
| 1993 | M S Saag, E A Emini, O L Laskin, J Douglas, W I Lapidus, W A Schleif, R J Whitley, C Hildebrand, V W Byrnes, John C Kappes | A short-term clinical evaluation of L... | |
| 1993 | C T Wang, Yongqing Zhang, J McDermott, E Barklis | Conditional infectivity of a human im... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, Erik De Clercq | Knocking-out concentrations of HIV-1-... | |
| 1993 | A Hizi, R Tal, M Shaharabany, M J Currens, M R Boyd, Stephen H Hughes, James B McMahon | Specific inhibition of the reverse tr... | |
| 1993 | T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley | A mutation in reverse transcriptase o... | |
| 1993 | Paul L Boyer, M J Currens, James B McMahon, M R Boyd, Stephen H Hughes | Analysis of nonnucleoside drug-resist... | |
| 1993 | Xincang Li, E Amandoron, Mark A. Wainberg, Michael A. Parniak | Generation and characterization of mu... | |
| 1993 | D Chattopadhyay, B C Finzel, S H Munson, D B Evans, S K Sharma, N A Strakalaitus, D P Brunner, F M Eckenrode, Z Dauter, C Betzel, H M Einspahr | Crystallographic analyses of an activ... | |
| 1993 | Thomas A Steitz, S Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, J M Friedman, Lorena S Beese, P A Rice | Two DNA polymerases: HIV reverse tran... | |
| 1993 | Mark A. Wainberg, H Salomon, Bonnie Spira, L Mercure, J Wainberg, K Nagai, Z Bentwich, J Montaner | HIV resistance to anti-viral drugs. | |
| 1993 | Katarzyna Bebenek, J Abbotts, Samuel H Wilson, Thomas A Kunkel | Error-prone polymerization by HIV-1 r... | |
| 1993 | Myron F Goodman, S Creighton, Linda B Bloom, John Petruska | Biochemical basis of DNA replication ... | |
| 1993 | Jan Balzarini, Sonsoles Velazquez, A San-Felix, Anna Karlsson, M J Perez-Perez, María-José Camarasa, Erik De Clercq | Human immunodeficiency virus type 1-s... | |
| 1993 | R Sousa, Y J Chung, J P Rose, B C Wang | Crystal structure of bacteriophage T7... | |
| 1993 | Svetlana N Khodyreva, Vladimir N Podust, D S Sergeev, E M Ivanova, E I Frolova, A A Koshkin, T S Godovikova, V F Zarytova, Miria Ricchetti, Olga I Lavrik | Comparison of interactions of 5'-deri... | |
| 1993 | Robert W Sobol, W L Fisher, N L Reichenbach, A Kumar, William A Beard, Samuel H Wilson, R Charubala, W Pfleiderer, R J Suhadolnik | HIV-1 reverse transcriptase: inhibiti... | |
| 1993 | Erik De Clercq | Antiviral agents: characteristic acti... | |
| 1993 | William A Beard, Samuel H Wilson | Kinetic analysis of template.primer i... | |
| 1993 | G Maass, U Immendoerfer, B Koenig, U Leser, B Mueller, R Goody, E Pfaff | Viral resistance to the thiazolo-iso-... | |
| 1993 | Zeger Debyser, K De Vreese, P P Knops-Gerrits, V Baekelandt, R Bhikhabhai, B Strandberg, Rudi Pauwels, J Anné, J Desmyter, Erik De Clercq | Kinetics of different human immunodef... | |
| 1992 | J A Coates, Nick Cammack, H J Jenkinson, I M Mutton, B A Pearson, R Storer, J M Cameron, C R Penn | The separated enantiomers of 2'-deoxy... | |
| 1992 | G T Tan, A Wickramasinghe, S Verma, R Singh, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan | Potential anti-AIDS naphthalenesulfon... | |
| 1992 | J C Boyer, Katarzyna Bebenek, Thomas A Kunkel | Unequal human immunodeficiency virus ... | |
| 1992 | L Ding, Jan Balzarini, Dominique Schols, B Meunier, Erik De Clercq | Anti-human immunodeficiency virus eff... | |
| 1992 | Z Hostomsky, Z Hostomska, T B Fu, J Taylor | Reverse transcriptase of human immuno... | |
| 1992 | William C Copeland, M S Chen, Teresa S-F Wang | Human DNA polymerases alpha and beta ... | |
| 1992 | J E Reardon | Human immunodeficiency virus reverse ... | |
| 1992 | Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg | Novel mutation in the human immunodef... | |
| 1992 | John W Mellors, Ginger E Dutschman, G J Im, Enzo Tramontano, S R Winkler, Yung-Chi Cheng | In vitro selection and molecular char... | |
| 1992 | N Yamamoto, Dominique Schols, Erik De Clercq, Zeger Debyser, Rudi Pauwels, Jan Balzarini, H Nakashima, Masanori Baba, M Hosoya, Robert Snoeck | Mechanism of anti-human immunodeficie... | |
| 1992 | I I Fedorov, E M Kazmina, N A Novicov, Galina V Gurskaya, A V Bochkarev, M V Jasko, L S Victorova, M K Kukhanova, Jan Balzarini, Erik De Clercq | 3'-C-branched 2'-deoxy-5-methyluridin... | |
| 1992 | Hong Yu, Myron F Goodman | Comparison of HIV-1 and avian myelobl... | |
| 1992 | D L Mayers, F E McCutchan, E E Sanders-Buell, L I Merritt, S Dilworth, A K Fowler, C A Marks, N M Ruiz, Douglas D Richman, C R Roberts | Characterization of HIV isolates aris... | |
| 1992 | Alberto Bergamini, CF Perno, Jan Balzarini, M Capozzi, Luciana Marinelli, G Milanese, C D Pesce, R Calió, G Rocchi | Selective inhibition of HIV replicati... | |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Dominique Schols, CF Perno, A-M Vandamme, María-José Camarasa, Erik De Clercq | 2',5'-Bis-O-(tert-butyldimethylsilyl)... | |
| 1992 | W M Kati, Kenneth A Johnson, L F Jerva, Karen S Anderson | Mechanism and fidelity of HIV reverse... | |
| 1992 | R L Mitina, S V Doronin, M I Dobrikov, D R Tabatadze, A S Levina, Olga I Lavrik | Human immunodeficiency virus type 1 r... | |
| 1992 | Shunji Izuta, N Shimada, Masatoshi Kitagawa, Motoshi Suzuki, K Kojima, Shonen Yoshida | Inhibitory effects of triphosphate de... | |
| 1992 | P Kellam, Charles A B Boucher, Brendan A Larder | Fifth mutation in human immunodeficie... | |
| 1992 | Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, Masanori Baba, J Desmyter, Erik De Clercq | Kinetics of inhibition of endogenous ... | |
| 1992 | K De Vreese, Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, J Desmyter, Erik De Clercq, J Anné | Resistance of human immunodeficiency ... | |
| 1992 | Erik De Clercq | HIV inhibitors targeted at the revers... | |
| 1992 | Erik De Clercq | New perspectives for the chemotherapy... | |
| 1992 | Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Y Engelborghs, Paul A J Janssen, Erik De Clercq | Allosteric inhibition of human immuno... | |
| 1992 | Zeger Debyser, Rudi Pauwels, Koen Andries, Erik De Clercq | Specific HIV-1 reverse transcriptase ... | |
| 1992 | A Basu, S Basu, Mukund J Modak | Structure-activity analyses of HIV-1 ... | |
| 1992 | S F Lacey, J E Reardon, E S Furfine, Thomas A Kunkel, Katarzyna Bebenek, Kristin A Eckert, S D Kemp, Brendan A Larder | Biochemical studies on the reverse tr... | |
| 1992 | M B Vasudevachari, C Battista, H C Lane, M C Psallidopoulos, B Zhao, J Cook, J R Palmer, D L Romero, W G Tarpley, N P Salzman | Prevention of the spread of HIV-1 inf... | |
| 1992 | F Boulerice, R Geleziunas, S Bour, H L Li, M D'Addario, A Roulston, J Hiscott, Mark A. Wainberg | Differential susceptibilities of U-93... | |
| 1992 | M Jiang, J Mak, Mark A. Wainberg, Michael A. Parniak, E Cohen, Lawrence Kleiman | Variable tRNA content in HIV-1IIIB. | |
| 1992 | Mark A. Wainberg, R G Margolese | Strategies in the treatment of AIDS a... | |
| 1992 | M Bakhanashvili, A Hizi | Fidelity of the reverse transcriptase... | RT,3-5' exo,All properties |
| 1992 | J J DeStefano, R G Buiser, L M Mallaber, P J Fay, Robert A Bambara | Parameters that influence processive ... | RT,Full length or truncated,Specific Activity,Processivity,Molecular Weight,RNase H,All properties |
| 1992 | Q Gao, Z X Gu, Michael A. Parniak, X G Li, Mark A. Wainberg | In vitro selection of variants of hum... | |
| 1992 | J A Coates, Nick Cammack, H J Jenkinson, A J Jowett, M I Jowett, B A Pearson, C R Penn, P L Rouse, K C Viner, J M Cameron | (-)-2'-deoxy-3'-thiacytidine is a pot... | |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, I C Bathurst, P J Barr, Erik De Clercq | Kinetics of inhibition of human immun... | |
| 1992 | J A Peliska, Stephen J Benkovic | Mechanism of DNA strand transfer reac... | |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velazquez, María-José Camarasa, Erik De Clercq | [2',5'-Bis-O-(tert-butyldimethylsilyl... | |
| 1992 | A Basu, K K Ahluwalia, S Basu, Mukund J Modak | Identification of the primer binding ... | |
| 1992 | J Abbotts, Samuel H Wilson | Inhibitors of HIV-1 reverse transcrip... | |
| 1992 | C S Crumpacker | Mechanism of action of foscarnet agai... | |
| 1992 | Zeger Debyser, K De Vreese, Rudi Pauwels, N Yamamoto, J Anné, Erik De Clercq, J Desmyter | Differential inhibitory effects of TI... | |
| 1992 | V V Sardana, E A Emini, L Gotlib, D J Graham, D W Lineberger, W J Long, A J Schlabach, J A Wolfgang, J H Condra | Functional analysis of HIV-1 reverse ... | |
| 1992 | L A Kohlstaedt, Jianhong Wang, J M Friedman, P A Rice, Thomas A Steitz | Crystal structure at 3.5 A resolution... | |
| 1992 | M M Huang, Norman Arnheim, Myron F Goodman | Extension of base mispairs by Taq DNA... | |
| 1992 | V Gopalakrishnan, J A Peliska, Stephen J Benkovic | Human immunodeficiency virus type 1 r... | RT,Terminal Transferase,RNase H,All properties |
| 1992 | J P Ji, Lawrence A Loeb | Fidelity of HIV-1 reverse transcripta... | |
| 1992 | L A Kohlstaedt, Thomas A Steitz | Reverse transcriptase of human immuno... | |
| 1992 | Brendan A Larder | 3'-Azido-3'-deoxythymidine resistance... | |
| 1992 | G T Tan, J F Miller, A D Kinghorn, Stephen H Hughes, J M Pezzuto | HIV-1 and HIV-2 reverse transcriptase... | |
| 1992 | S Loya, R Tal, Stephen H Hughes, A Hizi | The effects of cysteine mutations on ... | |
| 1992 | Tsuyoshi Yamaguchi, Shunji Izuta, Motoshi Suzuki, Shonen Yoshida, Akio Matsukage, Mineo Saneyoshi | Inhibitory effects of 2'-deoxy-5-styr... | |
| 1992 | A Hosmalin, S Kumar, D Barnd, R Houghten, G E Smith, Stephen H Hughes, J A Berzofsky | Immunization with soluble protein-pul... | |
| 1992 | Edward Arnold, A Jacobo-Molina, R G Nanni, R L Williams, Xiaoqing Lu, Jianping Ding, Art D Clark, A Zhang, Andrea L Ferris, Patrick K Clark | Structure of HIV-1 reverse transcript... | |
| 1992 | Paul L Boyer, Andrea L Ferris, Stephen H Hughes | Mutational analysis of the fingers do... | |
| 1991 | Mark A. Wainberg, R Rooke, M Tremblay, Xincang Li, Michael A. Parniak, Q Gao, X J Yao, C Tsoukas, J Montaner, M Fanning, J Ruedy | Clinical significance and characteriz... | |
| 1991 | E B Kopp, J J Miglietta, A G Shrutkowski, C K Shih, P M Grob, M T Skoog | Steady state kinetics and inhibition ... | KM,kcat,All properties |
| 1991 | Olga I Lavrik | Oligonucleotides and their derivative... | |
| 1991 | Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, R T Walker, S Mori | Highly potent and selective inhibitio... | |
| 1991 | M Tisdale, T Schulze, Brendan A Larder, K Moelling | Mutations within the RNase H domain o... | |
| 1991 | R S Goody, B Müller, Tobias Restle | Factors contributing to the inhibitio... | |
| 1991 | Brendan A Larder, K E Coates, S D Kemp | Zidovudine-resistant human immunodefi... | |
| 1991 | J Abbotts, M Jaju, Samuel H Wilson | Thermodynamics of A:G mismatch poly(d... | |
| 1991 | Mark Cushman, S Kanamathareddy, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen | Synthesis and anti-HIV activities of ... | |
| 1991 | Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Michael Kukla, Paul A J Janssen, Erik De Clercq | An antiviral target on reverse transc... | |
| 1991 | D Richman, C K Shih, I Lowy, J Rose, P Prodanovich, S Goff, J Griffin | Human immunodeficiency virus type 1 m... | |
| 1991 | E S Furfine, J E Reardon | Reverse transcriptase.RNase H from th... | RT,All properties |
| 1991 | J G Baillon, N T Nashed, A Kumar, Samuel H Wilson, Donald M Jerina | A leucine zipper-like motif may media... | |
| 1991 | Robert W Sobol, R J Suhadolnik, A Kumar, B J Lee, D L Hatfield, Samuel H Wilson | Localization of a polynucleotide bind... | |
| 1991 | Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, H Nakashima, S Mori | Potent and selective inhibition of hu... | |
| 1991 | A S De Groot, M Clerici, A Hosmalin, Stephen H Hughes, D Barnd, C W Hendrix, R Houghten, G M Shearer, J A Berzofsky | Human immunodeficiency virus reverse ... | |
| 1991 | G T Tan, A D Kinghorn, Stephen H Hughes, J M Pezzuto | Psychotrine and its O-methyl ether ar... | |
| 1991 | A Hizi, R Tal, Stephen H Hughes | Mutational analysis of the DNA polyme... | |
| 1991 | Jan Balzarini, Antonin Holy, J Jindrich, H Dvorakova, Z Hao, Robert Snoeck, Piet Herdewijn, D G Johns, Erik De Clercq | 9-[(2RS)-3-fluoro-2-phosphonylmethoxy... | |
| 1991 | S P Becerra, A Kumar, M S Lewis, S G Widen, J Abbotts, E M Karawya, Stephen H Hughes, J Shiloach, Samuel H Wilson, M S Lewis | Protein-protein interactions of HIV-1... | |
| 1991 | Mark Cushman, P L Wang, S H Chang, C Wild, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen | Preparation and anti-HIV activities o... | |
| 1991 | A Jacobo-Molina, Edward Arnold | HIV reverse transcriptase structure-f... | |
| 1991 | J E Reardon, E S Furfine, N Cheng | Human immunodeficiency virus reverse ... | |
| 1991 | M H St Clair, J L Martin, G Tudor-Williams, M C Bach, C L Vavro, D M King, P Kellam, S D Kemp, Brendan A Larder | Resistance to ddI and sensitivity to ... | |
| 1991 | P R Johnson, T E Hamm, S Goldstein, S Kitov, V M Hirsch | The genetic fate of molecularly clone... | |
| 1991 | A DeVico, R C Montelaro, R C Gallo, M G Sarngadharan | Purification and partial characteriza... | RT,Full length or truncated,3-5' exo,Nucleotide Substitution Rate,RNase H,All properties |
| 1991 | Erik De Clercq | Chemotherapy of the acquired immune d... | |
| 1991 | J H Nunberg, W A Schleif, E J Boots, J A O'Brien, J C Quintero, J M Hoffman, E A Emini, M E Goldman | Viral resistance to human immunodefic... | |
| 1991 | F Boulerice, X G Li, A Lvovich, Mark A. Wainberg | Recovery of infectious human immunode... | |
| 1991 | Stuart F J Le Grice, T Naas, B Wohlgensinger, O Schatz | Subunit-selective mutagenesis indicat... | |
| 1991 | K B Frank, G J Noll, E V Connell, I S Sim | Kinetic interaction of human immunode... | |
| 1991 | P Hafkemeyer, K Neftel, R Hobi, A Pfaltz, H Lutz, K Lüthi, Federico Focher, Silvio Spadari, Ulrich Hübscher | HP 0.35, a cephalosporin degradation ... | RT,RNase H,All properties |
| 1990 | Stuart F J Le Grice, F Grüninger-Leitch | Rapid purification of homodimer and h... | |
| 1990 | Mark A. Wainberg, Bonnie Spira, G Bleau, R Thomas | Inactivation of human immunodeficienc... | |
| 1990 | V J Merluzzi, K D Hargrave, M Labadia, K Grozinger, M Skoog, J C Wu, C K Shih, K Eckner, S Hattox, J Adams | Inhibition of HIV-1 replication by a ... | |
| 1990 | W E Müller, E Matthes, P Reuter, R Wenger, K Friese, Y Kuchino, H C Schröder | Effect of nonviable preparations from... | |
| 1990 | M Ricchetti, H Buc | Reverse transcriptases and genomic va... | |
| 1990 | Brendan A Larder, B Chesebro, Douglas D Richman | Susceptibilities of zidovudine-suscep... | |
| 1990 | A I Glukhov, S A Gordeev, S V Vinogradov, V I Kiselev, V M Kramarov, O I Kiselev, E S Severin | Amplification of DNA sequences of Eps... | |
| 1990 | J E Reardon, W H Miller | Human immunodeficiency virus reverse ... | KM,kcat,All properties |
| 1990 | A Hizi, Stephen H Hughes, M Shaharabany | Mutational analysis of the ribonuclea... | |
| 1990 | Andrea L Ferris, A Hizi, S D Showalter, S Pichuantes, L Babe, C S Craik, Stephen H Hughes | Immunologic and proteolytic analysis ... | |
| 1990 | Z Hao, D A Cooney, D Farquhar, CF Perno, K Zhang, R Masood, Y Wilson, N R Hartman, Jan Balzarini, D G Johns | Potent DNA chain termination activity... | |
| 1990 | F Boulerice, Mark A. Wainberg | Inhibition by AZT of HIV-1 replicatio... | |
| 1990 | M Tremblay, K Numazaki, X G Li, M Gornitsky, J Hiscott, Mark A. Wainberg | Resistance to infection by HIV-1 of p... | |
| 1990 | Erik De Clercq | Selective virus inhibitors. | |
| 1990 | S P Becerra, G M Clore, A M Gronenborn, A R Karlström, S J Stahl, Samuel H Wilson, P T Wingfield | Purification and characterization of ... | |
| 1990 | A M Barber, A Hizi, J V Maizel, Stephen H Hughes | HIV-1 reverse transcriptase: structur... | |
| 1990 | K J Williams, Lawrence A Loeb, M Fry | Synthesis of DNA by human immunodefic... | |
| 1990 | R Rooke, M Tremblay, Mark A. Wainberg | AZT (zidovudine) may act postintegrat... | |
| 1990 | Padmini S Kedar, J Abbotts, T Kovács, K Lesiak, P Torrence, Samuel H Wilson | Mechanism of HIV reverse transcriptas... | |
| 1990 | M Tremblay, K Numazaki, H Goldman, Mark A. Wainberg | Infection of human thymic lymphocytes... | |
| 1990 | Erik De Clercq | Targets and strategies for the antivi... | |
| 1989 | C Majumdar, C A Stein, J S Cohen, S Broder, Samuel H Wilson | Stepwise mechanism of HIV reverse tra... | |
| 1989 | H E Huber, J M McCoy, J S Seehra, Charles C Richardson | Human immunodeficiency virus 1 revers... | Processivity,3-5' exo,5-3' exo,KM,Kd,RNase H,All properties |
| 1989 | M Tremblay, Mark A. Wainberg | Susceptibility of EBV-carrying B cell... | |
| 1989 | M Tremblay, M Gornitsky, Mark A. Wainberg | Active replication of human immunodef... | |
| 1989 | B Müller, Tobias Restle, S Weiss, M Gautel, G Sczakiel, R S Goody | Co-expression of the subunits of the ... | |
| 1989 | A Basu, R S Tirumalai, Mukund J Modak | Substrate binding in human immunodefi... | |
| 1989 | M Ito, Masanori Baba, A Sato, K Hirabayashi, F Tanabe, S Shigeta, Erik De Clercq | Tumor necrosis factor enhances replic... | |
| 1989 | Masanori Baba, Dominique Schols, H Nakashima, Rudi Pauwels, G Parmentier, D K Meijer, Erik De Clercq | Selective activity of several cholic ... | |
| 1989 | Dominique Schols, Masanori Baba, Rudi Pauwels, Erik De Clercq | Flow cytometric method to demonstrate... | |
| 1989 | A Hizi, A Barber, Stephen H Hughes | Effects of small insertions on the RN... | |
| 1989 | Fred W Perrino, Bradley D Preston, L L Sandell, Lawrence A Loeb | Extension of mismatched 3' termini of... | |
| 1989 | Masanori Baba, Hiromichi Tanaka, Erik De Clercq, Rudi Pauwels, Jan Balzarini, Dominique Schols, H Nakashima, CF Perno, R T Walker, T Miyasaka | Highly specific inhibition of human i... | |
| 1989 | K Numazaki, X Q Bai, H Goldman, I Wong, Bonnie Spira, Mark A. Wainberg | Infection of cultured human thymic ep... | |
| 1989 | Brendan A Larder, S D Kemp | Multiple mutations in HIV-1 reverse t... | |
| 1989 | Erik De Clercq | Potential drugs for the treatment of ... | |
| 1988 | Sujit Roy, L Fitz-Gibbon, L Poulin, Mark A. Wainberg | Infection of human monocytes/macropha... | |
| 1988 | Masanori Baba, Rudi Pauwels, Jan Balzarini, J Arnout, J Desmyter, Erik De Clercq | Mechanism of inhibitory effect of dex... | |
| 1988 | J D Roberts, Katarzyna Bebenek, Thomas A Kunkel | The accuracy of reverse transcriptase... | |
| 1988 | Bradley D Preston, B J Poiesz, Lawrence A Loeb | Fidelity of HIV-1 reverse transcriptase. | |
| 1988 | M Tremblay, L Fitz-Gibbon, Mark A. Wainberg | Heterogeneity of HIV-1 replication an... | |
| 1988 | Masanori Baba, Dominique Schols, Rudi Pauwels, Jan Balzarini, Erik De Clercq | Fuchsin acid selectively inhibits hum... | |
| 1988 | E M Wondrak, J Löwer, R Kurth | Inhibition of HIV-1 RNA-dependent DNA... | |
| 1988 | Erik De Clercq | Perspectives for the chemotherapy of ... | |
| 1988 | A Hizi, C McGill, Stephen H Hughes | Expression of soluble, enzymatically ... | |
| 1987 | M Ito, H Nakashima, Masanori Baba, Rudi Pauwels, Erik De Clercq, S Shigeta, N Yamamoto | Inhibitory effect of glycyrrhizin on ... | |
| 1987 | Brendan A Larder, D J Purifoy, K L Powell, G Darby | Site-specific mutagenesis of AIDS vir... | |
| 1986 | F di Marzo Veronese, T D Copeland, A L DeVico, R Rahman, S Oroszlan, R C Gallo, M G Sarngadharan | Characterization of highly immunogeni... | |
| 1986 | M M Lightfoote, J E Coligan, T M Folks, A S Fauci, M A Martin, S Venkatesan | Structural characterization of revers... | |
| 1986 | H A Blough, Rudi Pauwels, Erik De Clercq, J Cogniaux, S Sprecher-Goldberger, L Thiry | Glycosylation inhibitors block the ex... | |
| 1986 | M S Johnson, M A McClure, D F Feng, J Gray, R F Doolittle | Computer analysis of retroviral pol g... | |
| 1985 | A D Hoffman, B Banapour, J A Levy | Characterization of the AIDS-associat... |
DNA sequence:
Protein information: Uniprot Q8Q292 search for HIV RT at UniProt
Sequence information: NCBI nucleotides European nucleotide archive