HIV RT
From
HIV
Welcome to the Polymerase Page
This page presents all the information in Polbase for HIV RT.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
HIV RT
is a family RT enzyme
from
HIV.
Selected Properties for HIV RT: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| No (4) | No (1) | 8.0e-06-4.7e-03 errors/bp (3) | 2.6e-05-3.2e-03 errors/bp (5) | 7.5e-05-8.0e-02 errors/bp (4) |
| Year | Authors | Title | Results by property |
|---|---|---|---|
| P Hafkemeyer, K A Neftel, Ulrich Hübscher | HIV-reverse transcriptase and human D... | ||
| Erik De Clercq | Perspectives for the chemotherapy of ... | ||
| Chen Liang, Mark A. Wainberg | The role of Tat in HIV-1 replication:... | ||
| Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari | Structural determinants of HIV-1 reve... | ||
| Maria Letizia Barreca, Laura De Luca, Nunzio Iraci, Angela Rao, Stefania Ferro, Giovanni Maga, Alba Chimirri | Structure-based pharmacophore identif... | ||
| Sherine S L Chan, Janine H Santos, Joel N Meyer, Bhaskar S Mandavilli, Dennis L Cook, Consuelo L McCash, Grace E Kissling, Abraham Nyska, Julie F Foley, Bennett Van Houten, William C Copeland, Vernon E Walker, Kristine L Witt, Jack B Bishop | Mitochondrial toxicity in hearts of C... | ||
| Mark A. Wainberg, S Bour, R Geleziunas, Z Bentwich | [Antiviral strategies in the replicat... | ||
| N Düzgünes, S Simões, V Slepushkin, E Pretzer, J J Rossi, Erik De Clercq, V P Antao, M L Collins, M C de Lima | Enhanced inhibition of HIV-1 replicat... | ||
| María-Cruz Bonache, Cristina Chamorro, Sonsoles Velázquez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Ana San-Félix | N-3 substituted TSAO derivatives as a... | ||
| Jorge L Martínez-Cajas, Nitika Pant-Pai, Marina B Klein, Mark A. Wainberg | Role of genetic diversity amongst HIV... | ||
| Erik De Clercq, Robert Snoeck | [Current acquisitions in antiviral dr... | ||
| G T Tan, J M Pezzuto, A D Kinghorn, Stephen H Hughes | Evaluation of natural products as inh... | ||
| Rudi Pauwels, M P de Bethune, Koen Andries, Paul Stoffels, P Janssen, Erik De Clercq | Discovery, development and characteri... | ||
| Erik De Clercq | Perspectives of non-nucleoside revers... | ||
| N Gashnikova, O Plyasunova, Y Kiseleva, N Fedyuk, A Pokrovsky | In vitro study of resistance-associat... | ||
| Erik De Clercq | Novel compounds in preclinical/early ... | ||
| Erik De Clercq | New developments in anti-HIV chemothe... | ||
| Paul J Lewi, Marc R De Jonge, Frits F D Daeyaert, Luc Koymans, Maarten H Vinkers, Jan Heeres, Paul A J Janssen, Edward Arnold, Kalyan Das, Art D Clark, Stephen H Hughes, Paul L Boyer, Marie-Pierre P De Béthune, Rudi Pauwels, Koen Andries, Michael Kukla, Donald W Ludovici, Bart De Corte, Robert W Kavash, Chih Y Ho, Paul J Lewis | On the detection of multiple-binding ... | ||
| 2013 | Xuwang Chen, Yuanyuan Li, Shufang Ding, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Huiqing Liu, Xinyong Liu | Discovery of Piperidine-Linked Pyridi... | |
| 2013 | Mikhail S Novikov, Vladimir T Valuev-Elliston, Denis A Babkov, Maria P Paramonova, Alexander V Ivanov, Sergey A Gavryushov, Anastasia L Khandazhinskaya, Sergey N Kochetkov, Christophe Pannecouque, Graciela Andrei, Robert Snoeck, Jan Balzarini, Katherine L Seley-Radtke | N(1),N(3)-disubstituted uracils as no... | |
| 2013 | Dongyue Li, Peng Zhan, Huiqing Liu, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2013 | Daniel G Kuroda, Joseph David Bauman, J Reddy Challa, Disha Patel, Thomas Troxler, Kalyan Das, Edward Arnold, Robin M Hochstrasser | Snapshot of the equilibrium dynamics ... | |
| 2013 | J-H Lee, Atsuko Hachiya, S-K Shin, J Lee, Hiroyuki Gatanaga, Shinichi Oka, Karen A Kirby, Yee Tsuey Ong, Stefan G Sarafianos, William R Folk, Wangdon Yoo, Sun Pyo Hong, S-O Kim | Restriction fragment mass polymorphis... | |
| 2013 | Kalyan Das, Edward Arnold | HIV-1 reverse transcriptase and antiv... | |
| 2013 | Kalyan Das, Edward Arnold | HIV-1 reverse transcriptase and antiv... | |
| 2013 | Hong-Tao Xu, Susan P Colby-Germinario, Eugene L Asahchop, Maureen Oliveira, Matthew McCallum, Susan M Schader, Yingshan Han, Yudong Quan, Stefan G Sarafianos, Mark A. Wainberg | The Effect of Mutations at Position E... | |
| 2013 | John E Tavis, Xiaohong Cheng, Yuan Hu, Michael Totten, Feng Cao, Eleftherios Michailidis, Rajeev Aurora, Marvin J Meyers, E Jon Jacobsen, Michael A. Parniak, Stefan G Sarafianos | The hepatitis B virus ribonuclease h ... | |
| 2013 | Mariela Bollini, Kathleen M Frey, José A Cisneros, Krasimir A Spasov, Kalyan Das, Joseph David Bauman, Edward Arnold, Karen S Anderson, William L Jorgensen | Extension into the entrance channel o... | |
| 2013 | A Heredia, CE Davis, MS Reitz, NM Le, MA Wainberg, JS Foulke, LX Wang, RR Redfield | Targeting of the Purine Biosynthesis ... | |
| 2013 | Jan Balzarini, Graciela Andrei, Emanuela Balestra, Dana Huskens, Christophe Vanpouille, Andrea Introini, Sonia Zicari, Sandra Liekens, Robert Snoeck, Antonín Holý, CF Perno, Leonid Margolis, Dominique Schols | A Multi-targeted Drug Candidate with ... | |
| 2013 | Ye Tian, Diwakar Rai, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Huiqing Liu, Xinyong Liu | Design, Synthesis, and Biological Eva... | |
| 2013 | Hai-Qiu Wu, Zi-Hong Yan, Wen-Xue Chen, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Dirk Daelemans, Christophe Pannecouque | Towards new C6-rigid S-DABO HIV-1 rev... | |
| 2013 | Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd | Inhibition of HIV-1 Reverse Transcrip... | |
| 2013 | Ravindra K Gupta, DA Van de Vijver, S Manicklal, MA Wainberg | Evolving uses of oral reverse transcr... | |
| 2013 | Karen A Kirby, Eleftherios Michailidis, Tracy L Fetterly, MA Steinbach, Kamalendra Singh, Bruno Marchand, Maxwell D Leslie, Ariel N Hagedorn, Eiichi N Kodama, Victor E Marquez, Stephen H Hughes, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Effects of 4' - and 2-Substitutions o... | |
| 2013 | Venkata Ramana Sirivolu, Sanjeev Kumar V Verneka, Tatiana Ilina, Nataliya S Myshakina, Michael A. Parniak, Zhengqiang Wang | Clicking 3'-azidothymidine into novel... | |
| 2013 | R S K Vijayan, Edward Arnold, Kalyan Das | Molecular dynamics study of HIV-1 RT-... | |
| 2013 | Matthew McCallum, Maureen Oliveira, Ruxandra-Ilinca Ibanescu, Victor G Kramer, Daniela D Moisi, Eugene L Asahchop, Bluma G Brenner, Richard Harrigan, Hongtao Xu, Mark A. Wainberg | Basis for the Early and Preferential ... | |
| 2013 | Erik De Clercq | The Nucleoside Reverse Transcriptase ... | |
| 2013 | Linda L Dunn, Paul L Boyer, Patrick K Clark, Stephen H Hughes | Mutations in HIV-1 reverse transcript... | |
| 2013 | Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno Marchand, Maxwell D Leslie, Andrew D Huber, Yee Tsuey Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Hypersusceptibility mechanism of Teno... | |
| 2013 | Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Xinyong Liu | Novel piperidinylamino-diarylpyrimidi... | |
| 2013 | Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Rita S Schildknecht, Hongtao Xu, Simani Gaseitswe, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg | The preferential selection of K65R in... | |
| 2013 | Joseph David Bauman, Disha Patel, Chhaya Dharia, Marc Fromer, Sameer Ahmed, Yulia Volovik Frenkel, J Thomas Eck, William C Ho, Kalyan Das, Aaron J Shatkin, Edward Arnold | Detecting allosteric sites of HIV-1 r... | |
| 2013 | Shiqiong Yang, Christophe Pannecouque, Dirk Daelemans, Xiao-Dong Ma, Yang Liu, Fen-Er Chen, Erik De Clercq | Molecular design, synthesis and biolo... | |
| 2012 | Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd | DNA Polymerase β Gap-filling Transles... | |
| 2012 | Barry C Johnson, Gary T Pauly, Ganesha Rai, Disha Patel, Joseph David Bauman, Heather L Baker, Kalyan Das, Joel P Schneider, David J Maloney, Edward Arnold, Craig J Thomas, Stephen H Hughes | A comparison of the ability of rilpiv... | |
| 2012 | Shuang-Xi Gu, Zhi-Ming Li, Xiao-Dong Ma, Shi-Qiong Yang, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Chiral resolution, absolute configura... | |
| 2012 | Victor G Kramer, Susan M Schader, Maureen Oliveira, Susan P Colby-Germinario, Daniel A Donahue, Diane N Singhroy, Randy Tressler, Richard D Sloan, Mark A. Wainberg | Maraviroc and other HIV-1 entry inhib... | |
| 2012 | Kalyan Das, Sergio E Martinez, Joseph David Bauman, Edward Arnold | HIV-1 reverse transcriptase complex w... | |
| 2012 | Peng Zhan, Xincang Li, Zhongjie Li, Xuwang Chen, Ye Tian, Wenmin Chen, Xinyong Liu, Christophe Pannecouque, Erik De Clercq | Structure-based bioisosterism design,... | |
| 2012 | Xuwang Chen, Peng Zhan, Xin Liu, Ziheng Cheng, Caicai Meng, Siyuan Shao, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Design, synthesis, anti-HIV evaluatio... | |
| 2012 | Karen A Kirby, Bruno Marchand, Yee Tsuey Ong, Tanyaradzwa P Ndongwe, Atsuko Hachiya, Eleftherios Michailidis, Maxwell D Leslie, Daniel V Sietsema, Tracy L Fetterly, Christopher A Dorst, Kamalendra Singh, Zhengqiang Wang, Michael A. Parniak, Stefan G Sarafianos | Structural and Inhibition Studies of ... | |
| 2012 | Tatiana Ilina, Krystal Labarge, Stefan G Sarafianos, Rieko Ishima, Michael A. Parniak | Inhibitors of HIV-1 Reverse Transcrip... | |
| 2012 | Ye Tian, Peng Zhan, Diwakar Rai, Jiyan Zhang, Erik De Clercq, Xinyong Liu | Recent advances in the research of 2,... | |
| 2012 | Eleftherios Michailidis, Kamlendra Singh, Emily M Ryan, Atsuko Hachiya, Yee Tsuey Ong, Karen A Kirby, Bruno Marchand, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Effect of translocation defective rev... | |
| 2012 | Sergio R Ribone, Volker Leen, Marcela Madrid, Wim Dehaen, Dirk Daelemans, Christophe Pannecouque, Margarita C Briñón | Synthesis, biological evaluation and ... | |
| 2012 | Shiqiong Yang, Fen-Er Chen, Erik De Clercq | Dihydro-alkoxyl-benzyl-oxopyrimidine ... | |
| 2012 | Dongyue Li, Peng Zhan, Erik De Clercq, Xinyong Liu | Strategies for the design of HIV-1 no... | |
| 2012 | Peng Zhan, Wenmin Chen, Zhongjie Li, Xincang Li, Xuwang Chen, Ye Tian, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Discovery of novel 2-(3-(2-chlorophen... | |
| 2012 | Wenwen Chen, Peng Zhan, Erik De Clercq, Xinyong Liu | Recent progress in small molecule CCR... | |
| 2012 | Eva-María Priego, Anna Karlsson, Federico Gago, María-José Camarasa, Jan Balzarini, María-Jesús Pérez-Pérez | Recent advances in thymidine kinase 2... | |
| 2012 | Xuwang Chen, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2012 | Christophe Vanpouille, Andrea Lisco, Andrea Introini, Jean-Charles Grivel, Arshi Munawwar, Melanie Merbah, Raymond F Schinazi, Marco Derudas, Christopher McGuigan, Jan Balzarini, Leonid Margolis | Exploiting the anti-HIV-1 activity of... | |
| 2012 | Xincang Li, Peng Zhan, Erik De Clercq, Xinyong Liu | The HIV-1 Non-Nucleoside Reverse Tran... | |
| 2012 | Zhongjie Li, Yuan Cao, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Arylazolylthioacetanilide. Part 11: D... | |
| 2012 | K O François, Jan Balzarini | Potential of carbohydrate-binding age... | |
| 2012 | Martin T Christen, Lakshmi Menon, Nataliya S Myshakina, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima | Structural basis of the allosteric in... | |
| 2012 | Kamalendra Singh, Bruno Marchand, Devendra K Rai, Bechan Sharma, Eleftherios Michailidis, Emily M Ryan, Kayla B Matzek, Maxwell D Leslie, Ariel N Hagedorn, Zhongjie Li, Pieter R Norden, Atsuko Hachiya, Michael A. Parniak, Hong-Tao Xu, Mark A. Wainberg, Stefan G Sarafianos | Biochemical Mechanism of HIV-1 Resist... | |
| 2012 | Wei-Shau Hu, Stephen H Hughes | HIV-1 Reverse Transcription. | |
| 2012 | Atsuko Hachiya, Bruno Marchand, Karen A Kirby, Eleftherios Michailidis, Xiongying Tu, Krzysztof Palczewski, Yee Tsuey Ong, Zhongjie Li, Daniel T Griffin, Matthew M Schuckmann, Junko Tanuma, Shinichi Oka, Kamalendra Singh, Eiichi N Kodama, Stefan G Sarafianos | HIV-1 reverse transcriptase (RT) poly... | |
| 2012 | Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valeria Famiglini, Sandro Cosconati, Giovanni Maga, Alberta Samuele, Emmanuel Gonzales, B Clotet, Dominique Schols, Jose Este, Ettore Novellino, Romano Silvestri | New Nitrogen Containing Substituents ... | |
| 2012 | Paul L Boyer, Patrick K Clark, Stephen H Hughes | HIV-1 and HIV-2 Reverse Transcriptase... | |
| 2012 | Dante Rotili, Alberta Samuele, Domenico Tarantino, Rino Ragno, Ira Musmuca, Flavio Ballante, Giorgia Botta, Ludovica Morera, Marco Pierini, Roberto Cirilli, Maxim B Nawrozkij, Emmanuel Gonzalez, B Clotet, Marino Artico, José A Esté, Giovanni Maga, Antonello Mai | 2-(Alkyl/Aryl)Amino-6-Benzylpyrimidin... | |
| 2012 | Marco Radi, Mafalda Pagano, Luigi Franchi, Daniele Castagnolo, Silvia Schenone, Gianni Casaluce, Claudio Zamperini, Elena Dreassi, Giovanni Maga, Alberta Samuele, Encarna Gonzalo, B Clotet, José A Esté, Maurizio Botta | Synthesis, Biological Activity, and A... | |
| 2012 | Serdal Kirmizialtin, Virginia Nguyen, Kenneth A Johnson, Ron Elber | How conformational dynamics of DNA po... | |
| 2012 | Christal D Sohl, Rajesh Kasiviswanathan, Jiae Kim, Ugo Pradere, Raymond F Schinazi, William C Copeland, Hiroyuki Mitsuya, Masanori Baba, Karen S Anderson | Balancing Antiviral Potency and Host ... | |
| 2012 | Changfu Yang, Shuyuan Liu, Taisong Zhang, Yaping Hou, Xiaoli Liu, Yun Gao, Guang Yang, Zhen Wang, Huayun Chen, Ming Li, Zhenyu Zhu | Transmitted antiretroviral drug resis... | |
| 2011 | Dimitrios Coutsinos, Cédric F Invernizzi, Daniela D Moisi, Maureen Oliveira, Jorge L Martinez-Cajas, Bluma G Brenner, Mark A. Wainberg | A template-dependent dislocation mech... | |
| 2011 | Mark A. Wainberg, Daniela D Moisi, Maureen Oliveira, Thomas D'Aquin Toni, Bluma G Brenner | Transmission dynamics of the M184V dr... | |
| 2011 | Hong-Tao Xu, Eugene L Asahchop, Maureen Oliveira, Peter K Quashie, Yudong Quan, Bluma G Brenner, Mark A. Wainberg | Compensation by the E138K mutation in... | |
| 2011 | Kalyan Das, Joseph David Bauman, Angela S Rim, Chhaya Dharia, Arthur D Clark, María-José Camarasa, Jan Balzarini, Edward Arnold | Crystal structure of tert-butyldimeth... | |
| 2011 | Matthias Götte | Initiation of HIV reverse transcripti... | |
| 2011 | Anick Auger, Greg L Beilhartz, Siqi Zhu, Elizabeth Cauchon, Jean-Pierre Falgueyret, Jay A Grobler, Maryam Ehteshami, Matthias Götte, Roman A Melnyk | Impact of primer-induced conformation... | |
| 2011 | Chandravanu Dash, Yousef Ahmadibeni, Michael J Hanley, Jui Pandhare, Mathias Gotte, Stuart F J Le Grice, Keykavous Parang | Inhibition of multi-drug resistant HI... | |
| 2011 | Brian J Scarth, Kirsten L White, James M Chen, Eric B Lansdon, S Swaminathan, Michael D Miller, Matthias Götte | Mechanism of resistance to GS-9148 co... | |
| 2011 | Brian J Scarth, Suzanne McCormick, Matthias Götte | Effects of mutations F61A and A62V in... | |
| 2011 | O Jegede, A Khodyakova, M Chernov, J Weber, L Menéndez-Arias, A Gudkov, ME Quiñones-Mateu | Identification of low-molecular weigh... | |
| 2011 | Erik De Clercq | A 40-year journey in search of select... | |
| 2011 | Xuwang Chen, Peng Zhan, Dongyue Li, Erik De Clercq, Xinyong Liu | Recent advances in DAPYs and related ... | |
| 2011 | Mingyan Yu, Zhongjie Li, Shuai Liu, Erkang Fan, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2011 | Peng Zhan, Xuwang Chen, Dongyue Li, Zengjun Fang, Erik De Clercq, Xinyong Liu | HIV-1 NNRTIs: Structural diversity, p... | |
| 2011 | Jing Zhang, Peng Zhan, Jingde Wu, Zhongjie Li, Yan Jiang, Weiying Ge, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2011 | Claudette S Satchell, Jane A O'Halloran, Aoife G Cotter, Aaron J Peace, Eileen F O'Connor, Anthony F Tedesco, Eoin R Feeney, John S Lambert, Gerard J Sheehan, Dermot Kenny, Patrick W G Mallon | Increased Platelet Reactivity in HIV-... | |
| 2011 | Allison K Delong, Mingham Wu, Diane Bennett, Neil Parkin, Zhijin Wu, Joseph W Hogan, Rami Kantor | Sequence Quality Analysis Tool (SQUAT... | |
| 2011 | Brian D Herman, Raymond F Schinazi, Hong-Wang Zhang, James H Nettles, Richard Stanton, Mervi Detorio, Aleksandr Obikhod, Ugo Pradère, Steven J Coats, John W Mellors, Nicolas Sluis-Cremer | Substrate mimicry: HIV-1 reverse tran... | |
| 2011 | Jing-Rong Ye, Lei Guo, Hong-Yan Lu, Ruo-Lei Xin, Yi Zeng | [Genotypic resistance mutations to an... | |
| 2011 | María-Cruz Bonache, Alessandra Cordeiro, Ernesto Quesada, Els Vanstreels, Dirk Daelemans, María-José Camarasa, Jan Balzarini, Ana San-Félix | Selective inhibition of Human Immunod... | |
| 2011 | Mikhail S Novikov, Olga N Ivanova, Alexander V Ivanov, Alexander A Ozerov, Vladimir T Valuev-Elliston, Kartik Temburnikar, Galina V Gurskaya, Sergey N Kochetkov, Christophe Pannecouque, Jan Balzarini, Katherine L Seley-Radtke | 1-[2-(2-Benzoyl- and 2-benzylphenoxy)... | |
| 2011 | Xiao-Dong Ma, Shi-Qiong Yang, Shuang-Xi Gu, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV activity of ar... | |
| 2011 | Graciela Andrei, Andrea Lisco, Christophe Vanpouille, Andrea Introini, Emanuela Balestra, Joost van den Oord, Tomas Cihlar, CF Perno, Robert Snoeck, Leonid Margolis, Jan Balzarini | Topical tenofovir, a microbicide effe... | |
| 2011 | Han-Ping Li, Wei Guo, Yong-Jian Liu, Zuo-Yi Bao, Lin Li, Dao-Min Zhuang, Si-Yang Liu, Zhengqiang Wang, Xiao-Lin Wang, Jing-Yun Li | [Screening program on novel drug resi... | |
| 2011 | Tao Dong, Yongqing Zhang, Ke Yi Xu, Huiping Yan, Ian James, Yanchun Peng, Marie-Eve Blais, Silvana Gaudieri, Xinyue Chen, Wenhui Lun, Hao Wu, Wen Yan Qu, Tim Rostron, Ning Li, Yu Mao, Simon Mallal, Xiaoning Xu, Andrew McMichael, Mina John, Sarah L Rowland-Jones | Extensive HLA-driven viral diversity ... | |
| 2011 | Qingguo Gong, Lakshmi Menon, Tatiana Ilina, Lena G Miller, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima | Interaction of HIV-1 reverse transcri... | |
| 2011 | Matthew W Kellinger, Kenneth A Johnson | Role of induced fit in limiting discr... | |
| 2011 | Zhinan Jin, Jerome Deval, Kenneth A Johnson, David C Swinney | Characterization of the elongation co... | |
| 2011 | Stefania Butini, Sandra Gemma, Margherita Brindisi, Giuseppe Borrelli, Isabella Fiorini, Alberta Samuele, Aristotele Karytinos, Marcella Facchini, Andrea Lossani, Samantha Zanoli, Giuseppe Campiani, Ettore Novellino, Federico Focher, Giovanni Maga | Enantioselective binding of second ge... | |
| 2011 | Dante Rotili, Domenico Tarantino, Marino Artico, Maxim B Nawrozkij, Emmanuel Gonzalez-Ortega, B Clotet, Alberta Samuele, José A Esté, Giovanni Maga, Antonello Mai | Diarylpyrimidine-dihydrobenzyloxopyri... | |
| 2011 | Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valerio Gatti, Giovanni Maga, Alberta Samuele, Christophe Pannecouque, Dominique Schols, Jan Balzarini, Ettore Novellino, Romano Silvestri | Indolylarylsulfones as HIV-1 non-nucl... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | N-3 Hydroxylation of Pyrimidine-2,4-d... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | 6-Benzoyl-3-hydroxypyrimidine-2,4-dio... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Mathieu Metifiot, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | 3-Hydroxypyrimidine-2,4-diones as an ... | |
| 2011 | Yuan Yuan, Hui Xing, Xiao-Yu Wang, Chun-hua Liu, Li-Ting Yang, Ben-Feng Zheng, Xia Wang, Yu-Hua Ruan, Zhe Wang, Hong-wei Liu, Yi-ming Shao | [The prevalence of HIV-1 drug resista... | |
| 2011 | Peibin Zeng, Jingxing Wang, Yi Huang, Xiaoming Guo, Jinming Li, Guoxin Wen, Tonghan Yang, Zhongqiao Yun, Miao He, Yu Liu, Yuzhe Yuan, Jane Schulmann, Simone Glynn, Paul Ness, J Brooks Jackson, Hua Shan | The human immunodeficiency virus-1 ge... | |
| 2011 | Alberta Samuele, Sara Bisi, Alexandra Kataropoulou, Giuseppe La Regina, Francesco Piscitelli, Valerio Gatti, Romano Silvestri, Giovanni Maga | Mechanism of interaction of novel ind... | |
| 2011 | Tanyaradzwa P Ndongwe, Adeyemi O Adedeji, Eleftherios Michailidis, Yee Tsuey Ong, Atsuko Hachiya, Bruno Marchand, Emily M Ryan, Devendra K Rai, Karen A Kirby, Angela S Whatley, Donald H Burke, Marc Johnson, Shilei Ding, Yi-Min Zheng, Shan-Lu Liu, Ei-Ichi Kodama, Krista A Delviks-Frankenberry, Vinay K Pathak, Hiroyuki Mitsuya, Michael A. Parniak, Kamalendra Singh, Stefan G Sarafianos | Biochemical, inhibition and inhibitor... | |
| 2011 | Mark A Ditzler, Debojit Bose, Nikolozi Shkriabai, Bruno Marchand, Stefan G Sarafianos, Mamuka Kvaratskhelia, Donald H Burke | Broad-spectrum aptamer inhibitors of ... | |
| 2011 | Karen A Kirby, Kamalendra Singh, Eleftherios Michailidis, Bruno Marchand, Eiichi N Kodama, Noriyuki Ashida, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | The sugar ring conformation of 4'-eth... | |
| 2011 | Atsuko Hachiya, Eiichi N Kodama, Matthew M Schuckmann, Karen A Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G Sarafianos | K70Q adds high-level tenofovir resist... | |
| 2011 | Joseph David Bauman, Disha Patel, Edward Arnold | Fragment Screening and HIV Therapeutics. | |
| 2011 | Anthony K Felts, Krystal Labarge, Joseph David Bauman, Dishaben V Patel, Daniel M Himmel, Edward Arnold, Michael A. Parniak, Ronald M Levy | Identification of alternative binding... | |
| 2011 | Suhman Chung, Daniel M Himmel, Jian-Kang Jiang, Krzysztof Wojtak, Joseph David Bauman, Jason W Rausch, Jennifer A Wilson, John A Beutler, Craig J Thomas, Edward Arnold, Stuart F J Le Grice | Synthesis, activity, and structural a... | |
| 2011 | Suhman Chung, Jennifer T Miller, Barry C Johnson, Stephen H Hughes, Stuart F J Le Grice | Mutagenesis of the human immunodefici... | |
| 2011 | Eugene L Asahchop, Maureen Oliveira, Mark A. Wainberg, Bluma G Brenner, Daniela D Moisi, Thomas D'Aquin Toni, Cecile L Tremblay | Characterization of the E138K resista... | |
| 2011 | Bluma G Brenner, Matthew Lowe, Daniela D Moisi, Isabelle Hardy, Simon Gagnon, Hugues Charest, Jean Guy Baril, Mark A. Wainberg, Michel Roger | Subtype diversity associated with the... | |
| 2010 | Martin Di Grandi, Matthew Olson, Amar S Prashad, Geraldine Bebernitz, Amara Luckay, Stanley Mullen, Yongbo Hu, Girija Krishnamurthy, Keith Pitts, John O'Connell | Small molecule inhibitors of HIV RT R... | |
| 2010 | Erik De Clercq | In search of a selective therapy of v... | |
| 2010 | Wujie Li, Mou Cao, Lu Pei, Xiaomei Ling, Bingchao Li, Zhenjun Yang | Study on steady-state kinetics of nuc... | RT,All properties |
| 2010 | Giovanni Maga, Marco Radi, Marie-Aline Gerard, Maurizio Botta, Eric Ennifar | HIV-1 RT Inhibitors with a Novel Mech... | |
| 2010 | Michael E Abram, Andrea L Ferris, Wei Shao, W Gregory Alvord, Stephen H Hughes | Nature, position, and frequency of mu... | |
| 2010 | Li-Jia Xu, Zong-Gen Peng, Hong-Shan Chen, Jie Wang, Pei-Gen Xiao | Bioactive triterpenoids from Kadsura ... | |
| 2010 | Viktor von Wyl, Maryam Ehteshami, Lisa M Demeter, Philippe Bürgisser, Monique Nijhuis, Jori Symons, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard | HIV-1 reverse transcriptase connectio... | |
| 2010 | H Nina Kim, Jing Wang, James Hughes, Robert Coombs, Jorge Sanchez, Stewart Reid, Sinead Delany-Moretlwe, Frances Cowan, Jonathan Fuchs, Susan H Eshleman, Leila Khaki, Moira A McMahon, Robert F Siliciano, Anna Wald, Connie Celum | Effect of acyclovir on HIV-1 set poin... | |
| 2010 | Romuald Corbau, Julie Mori, Chris Phillips, Lesley Fishburn, Alex Martin, Charles Mowbray, Wendy Panton, Caroline Smith-Burchnell, Adele Thornberry, Heather Ringrose, Thorsten Knöchel, Steve Irving, Mike Westby, Anthony Wood, Manos Perros | Lersivirine: a Non-Nucleoside Reverse... | RT,All properties |
| 2010 | Alberta Samuele, Emmanuele Crespan, Samanta Vitellaro, Anna-Maria Monforte, Patrizia Logoteta, Alba Chimirri, Giovanni Maga | Slow binding-tight binding interactio... | |
| 2010 | Hong-Tao Xu, Yudong Quan, Eugene L Asahchop, Maureen Oliveira, Daniella Moisi, Mark A. Wainberg | Comparative biochemical analysis of r... | |
| 2010 | Michael E Abram, Stefan G Sarafianos, Michael A. Parniak | The mutation T477A in HIV-1 reverse t... | |
| 2010 | Xiongying Tu, Kalyan Das, Qianwei Han, Joseph David Bauman, Arthur D Clark, Xiaorong Hou, Yulia Volovik Frenkel, Barbara L Gaffney, Roger A Jones, Paul L Boyer, Stephen H Hughes, Stefan G Sarafianos, Edward Arnold | Structural basis of HIV-1 resistance ... | |
| 2010 | Matthew M Schuckmann, Bruno Marchand, Atsuko Hachiya, Eiichi N Kodama, Karen A Kirby, Kamalendra Singh, Stefan G Sarafianos | The N348I mutation at the connection ... | |
| 2010 | Daniel A Donahue, Richard D Sloan, Björn D Kuhl, Tamara Bar-Magen, Susan M Schader, Mark A. Wainberg | Stage-dependent inhibition of HIV-1 r... | |
| 2010 | Matthias Götte, Jason W Rausch, Bruno Marchand, Stefan G Sarafianos, Stuart F J Le Grice | Reverse transcriptase in motion: conf... | |
| 2010 | Viktor von Wyl, Maryam Ehteshami, Jori Symons, Philippe Bürgisser, Monique Nijhuis, Lisa M Demeter, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard | Epidemiological and biological eviden... | |
| 2010 | Eric B Lansdon, Dharmaraj Samuel, Leanna Lagpacan, Katherine M Brendza, Kirsten L White, Magdeleine Hung, Xiaohong Liu, Constantine G Boojamra, Richard L Mackman, Tomas Cihlar, Adrian S Ray, Mary E McGrath, S Swaminathan | Visualizing the molecular interaction... | RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Polymerase Catalytic Residue Amino Acids,Residues Involved in Catalysis of RNase H,Incorporation of non-standard nucleotides,All properties |
| 2010 | Anna-Maria Monforte, Patrizia Logoteta, Laura De Luca, Nunzio Iraci, Stefania Ferro, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Novel 1,3-dihydro-benzimidazol-2-ones... | |
| 2010 | Suhman Chung, Michaela Wendeler, Jason W Rausch, Greg L Beilhartz, Matthias Gotte, Barry R O'Keefe, Alun Bermingham, John A Beutler, Shixin Liu, Xiaowei Zhuang, Stuart F J Le Grice | Structure-activity analysis of vinylo... | |
| 2010 | Hua-Poo Su, Youwei Yan, G Sridhar Prasad, Robert F Smith, Christopher L Daniels, Pravien D Abeywickrema, John C Reid, H Marie Loughran, Maria Kornienko, Sujata Sharma, Jay A Grobler, Bei Xu, Vinod Sardana, Timothy J Allison, Peter D Williams, Paul L Darke, Daria J Hazuda, Sanjeev Munshi | Structural basis for the inhibition o... | RT,RNase H,All properties |
| 2010 | Yuhua Ruan, Hui Xing, Xia Wang, Heng Tang, Zhengqiang Wang, Hongwei Liu, Bin Su, Jianjun Wu, Hanping Li, Lingjie Liao, Jinming Li, Julia Wei Wu, Yiming Shao | Virologic outcomes of first-line HAAR... | |
| 2010 | Zhengqiang Wang, Jing Tang, Christine E Salomon, Christine D Dreis, Robert Vince | Pharmacophore and structure-activity ... | |
| 2010 | Denis J Kertesz, Christine Brotherton-Pleiss, Minmin Yang, Zhengqiang Wang, Xianfeng Lin, Zongxing Qiu, Donald R Hirschfeld, Shelley K Gleason, Taraneh Mirzadegan, Pete W Dunten, Seth F Harris, Armando G Villaseñor, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp | Discovery of piperidin-4-yl-aminopyri... | RT,All properties |
| 2010 | Michael L Mitchell, Jong Chan Son, Ill Young Lee, Chong-Kyo Lee, Hae Soo Kim, Hongyan Guo, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Gene Eisenberg, Romas Geleziunas, Lianhong Xu, Choung U Kim | N1-Heterocyclic pyrimidinediones as n... | RT,All properties |
| 2010 | Brian D Herman, Ivan Votruba, Antonin Holy, Nicolas Sluis-Cremer, Jan Balzarini | The acyclic 2,4-diaminopyrimidine nuc... | |
| 2010 | Mia J Biondi, Greg L Beilhartz, Suzanne McCormick, Matthias Götte | N348I in HIV-1 reverse transcriptase ... | |
| 2010 | Michael L Mitchell, Jong Chan Son, Hongyan Guo, Yun-A Im, Eun Jung Cho, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Doris Graupe, Gerry Rhodes, Gong-Xin He, Romas Geleziunas, Lianhong Xu, Choung U Kim | N1-Alkyl pyrimidinediones as non-nucl... | RT,All properties |
| 2010 | Matthew W Kellinger, Kenneth A Johnson | Nucleotide-dependent conformational c... | RT,All properties |
| 2010 | Hong-Tao Xu, Maureen Oliveira, Yudong Quan, Tamara Bar-Magen, Mark A. Wainberg | Differential impact of the HIV-1 non-... | |
| 2010 | Séverine Freisz, Guillaume Bec, Marco Radi, Philippe Wolff, Emmanuele Crespan, Lucilla Angeli, Philippe Dumas, Giovanni Maga, Maurizio Botta, Eric Ennifar | Crystal Structure of HIV-1 Reverse Tr... | RT,All properties |
| 2010 | Guido van Marle, Deirdre L Church, Kali D Nunweiler, Kris Cannon, Mark A. Wainberg, M John Gill | Higher levels of Zidovudine resistant... | |
| 2010 | Eric B Lansdon, Katherine M Brendza, Magdeleine Hung, Ruth Wang, Susmith Mukund, Debi Jin, Gabriel Birkus, Nilima Kutty, Xiaohong Liu | Crystal structures of HIV-1 reverse t... | RT,Associated condition,All properties |
| 2010 | Guozhi Tang, Denis J Kertesz, Minmin Yang, Xianfeng Lin, Zhengqiang Wang, Wentao Li, Zongxing Qiu, Junli Chen, Jianghua Mei, Li Chen, Taraneh Mirzadegan, Seth F Harris, Armando G Villaseñor, Jennifer Fretland, William L Fitch, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp | Exploration of piperidine-4-yl-aminop... | |
| 2010 | Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq | 1,2,3-thiadiazole thioacetanilides. P... | |
| 2010 | Zhao-Sen Zeng, Qiu-Qin He, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Hybrid diarylbenzopyrimidine non-nucl... | |
| 2010 | Erik De Clercq | Antiretroviral drugs. | |
| 2010 | Zhao-Sen Zeng, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq | Lead optimization of diarylpyrimidine... | |
| 2010 | Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Bluma G Brenner, Mark A. Wainberg | Factors affecting template usage in t... | |
| 2010 | Yong-Hong Liang, Qiu-Qin He, Zhao-Sen Zeng, Zhi-Qian Liu, Xiao-Qing Feng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq | Synthesis and anti-HIV activity of 2-... | |
| 2010 | Greg L Beilhartz, Matthias Götte | HIV-1 Ribonuclease H: Structure, Cata... | |
| 2010 | John C Martin, Michael J M Hitchcock, Erik De Clercq, William H Prusoff | Early nucleoside reverse transcriptas... | |
| 2010 | Pankaj R Daga, Jinsong Duan, Robert J Doerksen | Computational model of hepatitis B vi... | |
| 2009 | Paul L Boyer, B Christie Vu, Zandrea Ambrose, John G Julias, Svenja Warnecke, Chenzhong Liao, Chris Meier, Victor E Marquez, Stephen H Hughes | The nucleoside analogue D-carba T blo... | |
| 2009 | Daniel M Himmel, Karen A Maegley, Tom A Pauly, Joseph David Bauman, Kalyan Das, Chhaya Dharia, Arthur D Clark, Kevin Ryan, Michael J Hickey, Robert A Love, Stephen H Hughes, Simon Bergqvist, Edward Arnold | Structure of HIV-1 reverse transcript... | RT,RNase H,All properties |
| 2009 | L Menéndez-Arias | Mutation Rates and Intrinsic Fidelity... | Frameshift Error Rate,All properties |
| 2009 | Kalyan Das, Rajiv P Bandwar, Kirsten L White, Joy Y Feng, Stefan G Sarafianos, Steven Tuske, Xiongying Tu, Arthur D Clark, Paul L Boyer, Xiaorong Hou, Barbara L Gaffney, Roger A Jones, Michael D Miller, Stephen H Hughes, Edward Arnold | Structural basis for the role of the ... | RT,All properties |
| 2009 | Yoshiyuki Mizushina, Hirohisa Motoshima, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Ken Hirano, Fumio Sugawara, Hiromi Yoshida | 3-O-methylfunicone, a selective inhib... | |
| 2009 | Marco Derudas, Davide Carta, Andrea Brancale, Christophe Vanpouille, Andrea Lisco, Leonid Margolis, Jan Balzarini, Christopher McGuigan | The application of phosphoramidate pr... | |
| 2009 | Anna-Maria Monforte, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Design, synthesis, and structure-acti... | |
| 2009 | Alexandra Kataropoulou, Chiara Bovolenta, Amalia Belfiore, Sonia Trabatti, Anna Garbelli, Simona Porcellini, Rossella Lupo, Giovanni Maga | Mutational analysis of the HIV-1 auxi... | |
| 2009 | Francesco Piscitelli, Antonio Coluccia, Andrea Brancale, Giuseppe La Regina, Anna Sansone, Cesare Giordano, Jan Balzarini, Giovanni Maga, Samantha Zanoli, Alberta Samuele, Roberto Cirilli, Francesco La Torre, Antonio Lavecchia, Ettore Novellino, Romano Silvestri | Indolylarylsulfones bearing natural a... | |
| 2009 | MC Puertas, MJ Buzón, A Artese, S Alcaro, L Menéndez-Arias, CF Perno, B Clotet, F Ceccherini-Silberstein, J Martinez-Picado | Effect of the human immunodeficiency ... | |
| 2009 | Stefania Butini, Margherita Brindisi, Sandro Cosconati, Luciana Marinelli, Giuseppe Borrelli, Salvatore Sanna Coccone, Anna Ramunno, Giuseppe Campiani, Ettore Novellino, Samantha Zanoli, Alberta Samuele, Gianluca Giorgi, Alberto Bergamini, Michela Di Mattia, Silvana Lalli, Bruno Galletti, Sandra Gemma, Giovanni Maga | Specific targeting of highly conserve... | |
| 2009 | Marco Radi, Giovanni Maga, Maddalena Alongi, Lucilla Angeli, Alberta Samuele, Samantha Zanoli, Luca Bellucci, Andrea Tafi, Gianni Casaluce, Gianluca Giorgi, Mercedes Armand-Ugon, Emmanuel Gonzalez, José A Esté, Mireille Baltzinger, Guillaume Bec, Philippe Dumas, Eric Ennifar, Maurizio Botta | Discovery of chiral cyclopropyl dihyd... | |
| 2009 | Peng Zhan, Xinyong Liu, Junjie Zhu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Synthesis and biological evaluation o... | |
| 2009 | Erik De Clercq | A new drug combination therapy for tr... | |
| 2009 | Peng Zhan, Xinyong Liu, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Design strategies of novel NNRTIs to ... | |
| 2009 | Peng Zhan, Xinyong Liu, Zengjun Fang, Christophe Pannecouque, Erik De Clercq | 1,2,3-Selenadiazole thioacetanilides:... | |
| 2009 | Peng Zhan, Xinyong Liu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Synthesis and anti-HIV activity evalu... | |
| 2009 | Peng Zhan, Zhongjie Li, Xinyong Liu, Erik De Clercq | Sulfanyltriazole/tetrazoles: a promis... | |
| 2009 | Yong-Hong Liang, Xiao-Qing Feng, Zhao-Sen Zeng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq | Design, synthesis, and SAR of naphthy... | |
| 2009 | Dharmesh H Mahajan, Christophe Pannecouque, Erik De Clercq, Kishor H Chikhalia | Synthesis and studies of new 2-(couma... | |
| 2009 | Franck Chiappini, Elina Teicher, Raphaël Saffroy, Brigitte Debuire, Daniel Vittecoq, Antoinette Lemoine | Relationship between polymerase gamma... | |
| 2009 | Linda L Dunn, Mary Jane McWilliams, Kalyan Das, Edward Arnold, Stephen H Hughes | Mutations in the thumb allow human im... | |
| 2009 | Kristina A Paris, Omar Haq, Anthony K Felts, Kalyan Das, Edward Arnold, Ronald M Levy | Conformational landscape of the human... | |
| 2009 | Erik De Clercq | Anti-HIV drugs: 25 compounds approved... | |
| 2009 | Bo-Liang Deng, Yaofeng Zhao, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis of alkenyldiarylmethanes (A... | |
| 2009 | Hironori Nishitsuji, Takaya Hayashi, Tomosaburo Takahashi, Masashi Miyano, Mari Kannagi, Takao Masuda | Augmentation of reverse transcription... | |
| 2009 | Egor P Tchesnokov, Aleksandr Obikhod, Ivana Massud, Andrea Lisco, Christophe Vanpouille, Beda Brichacek, Jan Balzarini, Christopher McGuigan, Marco Derudas, Leonid Margolis, Raymond F Schinazi, Matthias Götte | Mechanisms associated with HIV-1 resi... | |
| 2009 | Alberta Samuele, Alexandra Kataropoulou, Marco Viola, Samantha Zanoli, Giuseppe La Regina, Francesco Piscitelli, Romano Silvestri, Giovanni Maga | Non-nucleoside HIV-1 reverse transcri... | |
| 2009 | Stefan G Sarafianos, Bruno Marchand, Kalyan Das, Daniel M Himmel, Michael A. Parniak, Stephen H Hughes, Edward Arnold | Structure and function of HIV-1 rever... | |
| 2009 | Kazuki Izumi, Eiichi N Kodama, Kazuya Shimura, Yasuko Sakagami, Kentaro Watanabe, Saori Ito, Tsuyoshi Watabe, Yukihiro Terakawa, Hiroki Nishikawa, Stefan G Sarafianos, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka | Design of peptide-based inhibitors fo... | |
| 2009 | Dan Turner, Eduardo Shahar, Eugene Katchman, Eynat Kedem, Natasha Matus, Michal Katzir, Gamal Hassoun, Shimon Pollack, Rivka Kessner, Mark A. Wainberg, Boaz Avidor | Prevalence of the K65R resistance rev... | |
| 2009 | Greg L Beilhartz, Michaela Wendeler, Noel S Baichoo, Jason W Rausch, Stuart F J Le Grice, Matthias Götte | HIV-1 reverse transcriptase can simul... | |
| 2009 | Takuma Kimura, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Eiji Ohashi, Haruo Ohmori, Chikahide Masutani, Fumio Hanaoka, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Penicilliols A and B, novel inhibitor... | |
| 2009 | Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2009 | Takeshi Naito, Kazuki Izumi, Eiichi N Kodama, Yasuko Sakagami, Keiko Kajiwara, Hiroki Nishikawa, Kentaro Watanabe, Stefan G Sarafianos, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka | SC29EK, a peptide fusion inhibitor wi... | |
| 2009 | Atsuko Hachiya, Kazuki Shimane, Stefan G Sarafianos, Eiichi N Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi, Shinichi Oka | Clinical relevance of substitutions i... | |
| 2009 | Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg | Signature nucleotide polymorphisms at... | |
| 2009 | Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and in vitro anti-HIV evalu... | |
| 2009 | Yudong Quan, Chen Liang, Bluma G Brenner, Mark A. Wainberg | Multidrug-resistant variants of HIV t... | |
| 2009 | Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Daniela D Moisi, Maureen Oliveira, Bluma G Brenner, Mark A. Wainberg | Template usage is responsible for the... | |
| 2009 | Matthew D Cullen, William C Ho, Joseph David Bauman, Kalyan Das, Edward Arnold, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Crystallographic study of a novel sub... | RT,All properties |
| 2009 | Dai-Shi Su, John J Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J Felock, Meiqing Lu, Ming-Tain Lai, Sinoeun Touch, Gregory Moyer, Daniel J Distefano, Jessica A Flynn, Yuexia Liang, Rosa Sanchez, Sridhar Prasad, Youwei Yan, Rebecca A Perlow-Poehnelt, Maricel Torrent, Michael D Miller, Joe P Vacca, Theresa M Williams, Neville J Anthony | Substituted tetrahydroquinolines as p... | RT,All properties |
| 2009 | Susan P Colby-Germinario, Adan Rios, Jorge Quesada, Dallas Anderson, Allan L Goldstein, Theresa Fossum, Mark A. Wainberg | HIV inactivation by cross-linking of ... | |
| 2009 | Hongtao Xu, Yudong Quan, Bluma G Brenner, Tamara Bar-Magen, Maureen Oliveira, Susan M Schader, Mark A. Wainberg | Human immunodeficiency virus type 1 r... | |
| 2009 | Young-Sam Lee, W Dexter Kennedy, Y Whitney Yin | Structural insight into processive hu... | |
| 2009 | Xuexiang Zhang, Xueyan Jiang, Hongzhou Lu, Fang Shen, Jiangrong Wang | Dyslipidaemia and Intima-Media Thickn... | |
| 2009 | Thorsten A Kirschberg, Mini Balakrishnan, Neil H Squires, Tiffany Barnes, Katherine M Brendza, Xiaowu Chen, Eugene J Eisenberg, Weili Jin, Nilima Kutty, Stephanie Leavitt, Albert C Liclican, Qi Liu, Xiaohong Liu, John Mak, Jason K Perry, Michael Wang, William J Watkins, Eric B Lansdon | RNase H active site inhibitors of hum... | |
| 2009 | Anders Vahlne | A historical reflection on the discov... | |
| 2008 | Tatiana Ilina, Michael A. Parniak | Inhibitors of HIV-1 reverse transcrip... | |
| 2008 | Matthew D Cullen, York-Fong Cheung, Miles D Houslay, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Investigation of the alkenyldiarylmet... | |
| 2008 | Roger G Ptak, Philippe A Gallay, Dirk Jochmans, Andrew P Halestrap, Urs T Ruegg, Luke A Pallansch, Michael D Bobardt, Marie-Pierre P De Béthune, Johan Neyts, Erik De Clercq, Jean-Maurice Dumont, Pietro Scalfaro, Kamel Besseghir, Roland M Wenger, Brigitte Rosenwirth | Inhibition of human immunodeficiency ... | |
| 2008 | Michaela Wendeler, Hsiu-Fang Lee, Alun Bermingham, Jennifer T Miller, Oleg Chertov, Marion K Bona, Noel S Baichoo, Maryam Ehteshami, John A Beutler, Barry R O'Keefe, Matthias Götte, Mamuka Kvaratskhelia, Stuart F J Le Grice | Vinylogous ureas as a novel class of ... | |
| 2008 | Chandravanu Dash, Brian J Scarth, Christopher Badorrek, Matthias Götte, Stuart F J Le Grice | Examining the ribonuclease H primer g... | |
| 2008 | Patrick P Lestienne, François Boudsocq, Jacques E Bonnet | Initiation of DNA replication by a th... | |
| 2008 | Michel L Ntemgwa, Thomas D'Aquin Toni, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Maureen Oliveira, Mark A. Wainberg | Near full-length genomic analysis of ... | |
| 2008 | Takuma Kimura, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Novel azaphilones, kasanosins A and B... | |
| 2008 | Thomas J Tucker, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, John C Reid, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan | Discovery of 3-{5-[(6-amino-1H-pyrazo... | RT,All properties |
| 2008 | Jingshan Ren, Phillip P Chamberlain, Anna Stamp, Steven A Short, Kurt L Weaver, Karen R Romines, Richard J Hazen, Andrew Freeman, Robert G Ferris, C Webster Andrews, Lawrence R Boone, Joseph H Chan, David K Stammers | Structural basis for the improved dru... | RT,All properties |
| 2008 | Kalyan Das, Joseph David Bauman, Arthur D Clark, Yulia Volovik Frenkel, Paul J Lewi, Aaron J Shatkin, Stephen H Hughes, Edward Arnold | High-resolution structures of HIV-1 r... | RT,All properties |
| 2008 | Joseph David Bauman, Kalyan Das, William C Ho, Mukta Baweja, Daniel M Himmel, Arthur D Clark, Deena A Oren, Paul L Boyer, Stephen H Hughes, Aaron J Shatkin, Edward Arnold | Crystal engineering of HIV-1 reverse ... | RT,All properties |
| 2008 | Thorsten A Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty, Albert C Liclican, Damian J McColl, Neil H Squires, Eric B Lansdon | Triazole derivatives as non-nucleosid... | RT,All properties |
| 2008 | Zachary K Sweeney, Seth F Harris, Seth F Arora, Hassan Javanbakht, Yingqian Li, Jennifer Fretland, James P Davidson, J Roland Billedeau, Shelley K Gleason, Donald R Hirschfeld, Joshua J Kennedy-Smith, Taraneh Mirzadegan, Ralf Roetz, Mark Smith, Sarah Sperry, Judy M Suh, Jeffrey Wu, Stan Tsing, Armando G Villaseñor, Amber Paul, Guoping Su, Gabrielle M Heilek, Julie Qi Hang, Amy S Zhou, Jesper A Jernelius, Fang-Jie Zhang, Klaus Klumpp | Design of annulated pyrazoles as inhi... | RT,All properties |
| 2008 | Andrea Lisco, Christophe Vanpouille, Egor P Tchesnokov, Jean-Charles Grivel, Angélique Biancotto, Beda Brichacek, Julie Elliott, Emilie Fromentin, Robin Shattock, Peter Anton, Robert Gorelick, Jan Balzarini, Christopher McGuigan, Marco Derudas, Matthias Götte, Raymond F Schinazi, Leonid Margolis | Acyclovir is activated into a HIV-1 r... | RT,All properties |
| 2008 | Thomas J Tucker, Sandeep Saggar, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan | The design and synthesis of diaryl et... | RT,All properties |
| 2008 | Julie Lemay, Priscilla Maidou-Peindara, Reynel Cancio, Eric Ennifar, Gaël Coadou, Giovanni Maga, Jean-Christophe Rain, Richard Benarous, Lang Xia Liu | AKAP149 binds to HIV-1 reverse transc... | |
| 2008 | Anna-Maria Monforte, Angela Rao, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Maria Letizia Barreca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Novel N1-substituted 1,3-dihydro-2H-b... | |
| 2008 | Samantha Zanoli, Sandra Gemma, Stefania Butini, Margherita Brindisi, Bhupendra P Joshi, Giuseppe Campiani, Caterina Fattorusso, Marco Persico, Emmanuele Crespan, Reynel Cancio, Silvio Spadari, Ulrich Hübscher, Giovanni Maga | Selective targeting of the HIV-1 reve... | |
| 2008 | Alberta Samuele, Marcella Facchini, Dante Rotili, Antonello Mai, Marino Artico, Mercedes Armand-Ugón, José A Esté, Giovanni Maga | Substrate-induced stable enzyme-inhib... | |
| 2008 | Marco Radi, Chiara Falciani, Lorenzo Contemori, Elena Petricci, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Montserrat Terrazas, Marinunzia Castria, Andrea Togninelli, José A Esté, Imma Clotet-Codina, Mercedes Armand-Ugón, Maurizio Botta | A multidisciplinary approach for the ... | |
| 2008 | Bechan Sharma, Emmanuele Crespan, Giuseppe Villani, Giovanni Maga | The balance between the rates of inco... | |
| 2008 | Zhijian Zhao, Scott E Wolkenberg, Philip E J Sanderson, Meiqing Lu, Vandna Munshi, Gregory Moyer, Meizhen Feng, Anthony V Carella, Linda T Ecto, Lori J Gabryelski, Ming-Tain Lai, Sridar G Prasad, Youwei Yan, Georgia B McGaughey, Michael D Miller, Craig W Lindsley, George D Hartman, Joseph P Vacca, Theresa M Williams | Novel indole-3-sulfonamides as potent... | RT,All properties |
| 2008 | Bluma G Brenner, Michel Roger, Daniela D Moisi, Maureen Oliveira, Isabelle Hardy, Reuven Turgel, Hugues Charest, Jean-Pierre Routy, Mark A. Wainberg | Transmission networks of drug resista... | |
| 2008 | Samir Abdurahman, Akos Végvári, Masoud Youssefi, Michael Levi, Stefan Höglund, Elin Andersson, Peter Horal, Bo Svennerholm, Jan Balzarini, Anders Vahlne | Activity of the small modified amino ... | |
| 2008 | Atsuko Hachiya, Eiichi N Kodama, Stefan G Sarafianos, Matthew M Schuckmann, Yasuko Sakagami, Masao Matsuoka, Masafumi Takiguchi, Hiroyuki Gatanaga, Shinichi Oka | Amino acid mutation N348I in the conn... | |
| 2008 | Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and biological evaluation o... | |
| 2008 | Zhengqiang Wang, Robert Vince | Design and synthesis of dual inhibito... | |
| 2008 | Krista A Delviks-Frankenberry, Galina N Nikolenko, Paul L Boyer, Stephen H Hughes, John M Coffin, Abhay Jere, Vinay K Pathak | HIV-1 reverse transcriptase connectio... | |
| 2008 | Zhengqiang Wang, Robert Vince | Synthesis of pyrimidine and quinolone... | |
| 2008 | Zachary K Sweeney, James P Dunn, Yingqian Li, Gabrielle M Heilek, Pete W Dunten, Todd R Elworthy, Xiaochun Han, Seth F Harris, Donald R Hirschfeld, J Heather Hogg, Walter Huber, Ann C Kaiser, Denis J Kertesz, Woongki Kim, Taraneh Mirzadegan, Michael G Roepel, Y David Saito, Tania M P C Silva, Steven Swallow, Jahari L Tracy, Armando Villasenor, Harit Vora, Amy S Zhou, Klaus Klumpp | Discovery and optimization of pyridaz... | RT,All properties |
| 2008 | Maryam Ehteshami, Brian J Scarth, Egor P Tchesnokov, Chandravanu Dash, Stuart F J Le Grice, Sabine Hallenberger, Dirk Jochmans, Matthias Götte | Mutations M184V and Y115F in HIV-1 re... | |
| 2008 | Mitsuki Naganuma, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | 1-deoxyrubralactone, a novel specific... | |
| 2008 | Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte | Delayed chain termination protects th... | |
| 2008 | Maryam Ehteshami, Matthias Götte | Effects of mutations in the connectio... | |
| 2008 | Maryam Ehteshami, Greg L Beilhartz, Brian J Scarth, Egor P Tchesnokov, Suzanne McCormick, Brian Wynhoven, P Richard Harrigan, Matthias Götte | Connection domain mutations N348I and... | |
| 2008 | Jiaping Lai, Jun Wang, Zongwei Cai | Nucleoside reverse transcriptase inhi... | |
| 2008 | Guangwei Yang, Jianhong Wang, Yao Cheng, Ginger E Dutschman, Hiromichi Tanaka, Masanori Baba, Yung-Chi Cheng | Mechanism of inhibition of human immu... | |
| 2008 | Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Marco Ponassi, Torsten Unge, Martino Bolognesi | Crystal structures of HIV-1 reverse t... | RT,All properties |
| 2008 | Yueping Wang, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse-transcri... | |
| 2008 | Jangsuk Oh, Mary Jane McWilliams, John G Julias, Stephen H Hughes | Mutations in the U5 region adjacent t... | |
| 2008 | Lu Gao, Mark Nils Hanson, Mini Balakrishnan, Paul L Boyer, Bernard P Roques, Stephen H Hughes, Baek Kim, Robert A Bambara | Apparent defects in processive DNA sy... | |
| 2008 | Chong Fang, Joseph David Bauman, Kalyan Das, Amanda Remorino, Edward Arnold, Robin M Hochstrasser | Two-dimensional infrared spectra reve... | |
| 2008 | Yongcheng Song, Julian M W Chan, Zev Tovian, Aaron Secrest, Eva Nagy, Kilannin Krysiak, Kyle Bergan, Michael A. Parniak, Eric Oldfield | Bisphosphonate inhibitors of ATP-medi... | |
| 2008 | Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2008 | Fang Yu, Xinyong Liu, Peng Zhan, Erik De Clercq | Recent advances in the research of HI... | |
| 2008 | Scott J Garforth, Michael A. Parniak, Vinayaka R Prasad | Utilization of a deoxynucleoside diph... | |
| 2008 | Peng Zhan, Xinyong Liu, Yuan Cao, Yan Wang, Christophe Pannecouque, Erik De Clercq | 1,2,3-Thiadiazole thioacetanilides as... | |
| 2008 | Atsushi Kawamoto, Eiichi N Kodama, Stefan G Sarafianos, Yasuko Sakagami, Satoru Kohgo, Kenji Kitano, Noriyuki Ashida, Yuko Iwai, Hiroyuki Hayakawa, Hirotomo Nakata, Hiroyuki Mitsuya, Edward Arnold, Masao Matsuoka | 2'-deoxy-4'-C-ethynyl-2-halo-adenosin... | |
| 2008 | Erik De Clercq | Emerging antiviral drugs. | |
| 2008 | Ravindra K Rawal, Rajkamal Tripathi, Smitha Kulkarni, R Paranjape, S B Katti, Christophe Pannecouque, Erik De Clercq | 2-(2,6-Dihalo-phenyl)-3-heteroaryl-2-... | |
| 2008 | Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Design and synthesis of 2-(2,6-dibrom... | |
| 2007 | Yazan El Safadi, Valérie Vivet-Boudou, Roland Marquet | HIV-1 reverse transcriptase inhibitors. | RT,All properties |
| 2007 | Matthias Götte | Mechanisms of resistance associated w... | |
| 2007 | Kalyan Das, Stefan G Sarafianos, Arthur D Clark, Paul L Boyer, Stephen H Hughes, Edward Arnold | Crystal structures of clinically rele... | |
| 2007 | George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Matthias Gotte, Janice D Pata, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice | Investigating the "steric gate" of hu... | |
| 2007 | Scott J Garforth, Tae Woo Kim, Michael A. Parniak, Eric T Kool, Vinayaka R Prasad | Site-directed mutagenesis in the fing... | |
| 2007 | Lingjie Liao, Hui Xing, Xincang Li, Yuhua Ruan, Yongqing Zhang, Guangming Qin, Yiming Shao | Genotypic analysis of the protease an... | |
| 2007 | Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J Low, Peter K Cheung, P Richard Harrigan, Thomas Lengauer, Francisco S Domingues | Structural descriptors of gp120 V3 lo... | |
| 2007 | Sanjeewa Dharmasena, Zita Pongracz, Edward Arnold, Stefan G Sarafianos, Michael A. Parniak | 3'-Azido-3'-deoxythymidine-(5')-tetra... | RT,All properties |
| 2007 | Bruno Marchand, Egor P Tchesnokov, Matthias Götte | The pyrophosphate analogue foscarnet ... | RT,All properties |
| 2007 | Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, Joseph H Chan, Jörg-Peter Kleim, David K Stammers | Relationship of potency and resilienc... | RT,All properties |
| 2007 | Zabrina L Brumme, Chanson J Brumme, Celia K S Chui, Theresa Mo, Brian Wynhoven, Conan K Woods, Bethany M Henrick, Robert S Hogg, Julio S G Montaner, P Richard Harrigan | Effects of human leukocyte antigen cl... | |
| 2007 | Chanson J Brumme, P Richard Harrigan, Emma C Preston, Winnie W Y Dong, Brian Wynhoven, Carol Murphy, Julio S G Montaner | Transmission of drug-resistant HIV-1 ... | |
| 2007 | Shinji Kamisuki, Chisato Ishimaru, Kadohiro Onoda, Isoko Kuriyama, Noriko Ida, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Nodulisporol and Nodulisporone, novel... | |
| 2007 | Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, David Moore, Benita Yip, Evan Wood, Julio S G Montaner | Continued improvement in survival amo... | |
| 2007 | Hikaru Yamanaka, Hiroyuki Gatanaga, Pope Kosalaraksa, Saori Matsuoka-Aizawa, Tomonori Takahashi, Seisuke Kimura, Shinichi Oka | Novel mutation of human DNA polymeras... | |
| 2007 | Guangwei Yang, Ginger E Dutschman, Chuan-Jen Wang, Hiromichi Tanaka, Masanori Baba, Karen S Anderson, Yung-Chi Cheng | Highly selective action of triphospha... | |
| 2007 | Fernando A Frankel, Dimitrios Coutsinos, Hongtao Xu, Mark A. Wainberg | Kinetics of inhibition of HIV type 1 ... | |
| 2007 | Fernando A Frankel, Cédric F Invernizzi, Maureen Oliveira, Mark A. Wainberg | Diminished efficiency of HIV-1 revers... | |
| 2007 | Christian Castro, Eric D Smidansky, Kenneth R Maksimchuk, Jamie J Arnold, Victoria S Korneeva, Matthias Götte, William H Konigsberg, Craig E Cameron | Two proton transfers in the transitio... | |
| 2007 | Soo-Huey Yap, Chih-Wei Sheen, Jonathan Fahey, Mark Zanin, David Tyssen, Viviane Dias Lima, Brian Wynhoven, Michael Kuiper, Nicolas Sluis-Cremer, P Richard Harrigan, Gilda Tachedjian | N348I in the connection domain of HIV... | RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Storage requirements,RNase H,All properties |
| 2007 | Marshall L Morningstar, Thomas Roth, David W Farnsworth, Marilyn B Kroeger Smith, Karen M Watson, Robert W Buckheit, Kalyan Das, Weiming Zhang, Edward Arnold, John G Julias, Stephen H Hughes, Christopher J Michejda | Synthesis, biological activity, and c... | |
| 2007 | Silvia Bertagnolio, Luis Soto-Ramirez, Richard Pilon, Roberto Rodriguez, Monica Viveros, Luis Fuentes, P Richard Harrigan, Theresa Mo, Don Sutherland, Paul Sandstrom | HIV-1 drug resistance surveillance us... | |
| 2007 | Matthew D Cullen, Bo-Liang Deng, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis and biological evaluation o... | |
| 2007 | Qianwei Han, Stefan G Sarafianos, Edward Arnold, Michael A. Parniak, Barbara L Gaffney, Roger A Jones | Synthesis of AZTpSpCX2ppSA and AZTpSp... | |
| 2007 | Paul L Boyer, John G Julias, Zandrea Ambrose, Maqbool A Siddiqui, Victor E Marquez, Stephen H Hughes | The nucleoside analogs 4'C-methyl thy... | |
| 2007 | M R Loutfy, J M Raboud, J S G Montaner, T Antoniou, Brian Wynhoven, F Smaill, D Rouleau, J Gill, W Schlech, Zabrina L Brumme, Theresa Mo, K Gough, A Rachlis, P Richard Harrigan, S L Walmsley | Assay of HIV gp41 amino acid sequence... | |
| 2007 | L W Y Tam, Robert S Hogg, Benita Yip, J S G Montaner, P Richard Harrigan, Chanson J Brumme | Performance of a World Health Organiz... | |
| 2007 | Adrian S Ray, Joy Y Feng, Eisuke Murakami, Chung K Chu, Raymond F Schinazi, Karen S Anderson | Interaction of 2'-deoxyguanosine trip... | |
| 2007 | Andrew J Low, Winnie W Y Dong, Dennison Chan, Tobias Sing, Ronald Swanstrom, Mark Jensen, Satish Pillai, Benjamin Good, P Richard Harrigan | Current V3 genotyping algorithms are ... | |
| 2007 | Dirk Daelemans, Richard Lu, Erik De Clercq, Alan Engelman | Characterization of a replication-com... | |
| 2007 | Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Synthesis and evaluation of 2-(2,6-di... | |
| 2007 | Erik De Clercq | Anti-HIV drugs. | |
| 2007 | Takeshi Sakamoto, Matthew D Cullen, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis and anti-HIV activity of ne... | |
| 2007 | Ravindra K Rawal, Raj Kamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Synthesis and biological evaluation o... | |
| 2007 | Jingde Wu, Xinyong Liu, Xianchao Cheng, Yuan Cao, Defeng Wang, Zhongjie Li, Wenfang Xu, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq | Synthesis of novel derivatives of 4-a... | |
| 2007 | Alok Mulky, B Christie Vu, Joan A Conway, Stephen H Hughes, John C Kappes | Analysis of amino acids in the beta7-... | |
| 2007 | Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia K S Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P Richard Harrigan | Evidence of differential HLA class I-... | |
| 2007 | William C Drosopoulos, Vinayaka R Prasad | The active site residue Valine 867 in... | |
| 2007 | Jianbin Wang, H X Wang, T B Ng | A peptide with HIV-1 reverse transcri... | |
| 2007 | Wei-Hao Liao, Kuo-Jung Huang, Yu-Fen Chang, Shiu-Mei Wang, Ying-Tzu Tseng, Chien-Cheng Chiang, Jaang-Jiun Wang, Chin-Tien Wang | Incorporation of human immunodeficien... | |
| 2007 | Jianing Wang, Yunho Jin, Kimberly L Rapp, Raymond F Schinazi, Chung K Chu | D- and L-2',3'-didehydro-2',3'-dideox... | |
| 2007 | Celia K S Chui, Zabrina L Brumme, Chanson J Brumme, Benita Yip, Elizabeth J Phillips, Julio S G Montaner, P Richard Harrigan | A simple screening approach to reduce... | |
| 2007 | Clara E Cases-González, Sandra Franco, Miguel Angel Martínez, L Menéndez-Arias | Mutational patterns associated with t... | |
| 2007 | Krista A Delviks-Frankenberry, Galina N Nikolenko, Rebekah Barr, Vinay K Pathak | Mutations in human immunodeficiency v... | |
| 2007 | Dirk Eggink, Marleen C D G Huigen, Charles A B Boucher, Matthias Götte, Monique Nijhuis | Insertions in the beta3-beta4 loop of... | |
| 2007 | Zhengqiang Wang, Eric M Bennett, Daniel J Wilson, Christine E Salomon, Robert Vince | Rationally designed dual inhibitors o... | |
| 2007 | Kristel Van Laethem, Christophe Pannecouque, Anne-Mieke Vandamme | Mutations at 65 and 70 within the con... | |
| 2007 | P Richard Harrigan, Theresa Mo, Jennifer Hirsch, Zabrina L Brumme, Paula McKenna, Lee Bacheler | A 21-base pair insertion/duplication ... | |
| 2007 | Marleen C D G Huigen, Loek de Graaf, Dirk Eggink, Rob Schuurman, Viktor Müller, Anna Stamp, David K Stammers, Charles A B Boucher, Monique Nijhuis | Evolution of a novel 5-amino-acid ins... | |
| 2007 | Bruno Marchand, Kirsten L White, John K Ly, Nicolas A Margot, Ruth Wang, Martin J McDermott, Michael D Miller, Matthias Götte | Effects of the translocation status o... | |
| 2007 | Giovanni Maga, Marco Radi, Samantha Zanoli, Fabrizio Manetti, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Chiara Falciani, Montserrat Terrazas, Jaume Vilarrasa, Maurizio Botta | Discovery of non-nucleoside inhibitor... | |
| 2007 | Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna-Maria Monforte, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Alba Chimirri | Discovery of novel benzimidazolones a... | |
| 2007 | Reynel Cancio, Antonello Mai, Dante Rotili, Marino Artico, Gianluca Sbardella, Imma Clotet-Codina, José A Esté, Emmanuele Crespan, Samantha Zanoli, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Slow-, tight-binding HIV-1 reverse tr... | |
| 2007 | Kassim F Adebambo, Samantha Zanoli, Michael G Thomas, Reynel Cancio, Nicola M Howarth, Giovanni Maga | N2-benzyloxycarbonylguan-9-yl acetic ... | |
| 2007 | Stefania Paolucci, Fausto Baldanti, Giulia Campanini, Reynel Cancio, Amalia Belfiore, Giovanni Maga, Giuseppe Gerna | NNRTI-selected mutations at codon 190... | |
| 2007 | Galina N Nikolenko, Krista A Delviks-Frankenberry, Sarah Palmer, Frank Maldarelli, Matthew J Fivash, John M Coffin, Vinay K Pathak | Mutations in the connection domain of... | |
| 2007 | Giuseppe La Regina, Antonio Coluccia, Francesco Piscitelli, Alberto Bergamini, Anna Sinistro, Antonella Cavazza, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Ettore Novellino, Marino Artico, Romano Silvestri | Indolyl aryl sulfones as HIV-1 non-nu... | |
| 2007 | Michael G Thomas, Giovanni Maga, Jean-François Mouscadet, Nicola M Howarth | Investigation of novel lipid-function... | |
| 2007 | Tobias Sing, Andrew J Low, Niko Beerenwinkel, Oliver Sander, Peter K Cheung, Francisco S Domingues, Joachim Büch, Martin Däumer, Rolf Kaiser, Thomas Lengauer, P Richard Harrigan | Predicting HIV coreceptor usage on th... | |
| 2007 | Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh, Eiichi N Kodama, Guangwei Yang, Christopher M Bailey, Satoru Kohgo, Hiroyuki Hayakawa, Masao Matsuoka, Karen S Anderson, Yung-Chi Cheng, Hiroyuki Mitsuya | Activity against human immunodeficien... | |
| 2007 | Katharina Skrabal, Andrew J Low, Winnie W Y Dong, Tobias Sing, Peter K Cheung, Fabrizio Mammano, P Richard Harrigan | Determining human immunodeficiency vi... | |
| 2007 | Paul L Boyer, Carolyn R Stenbak, David Hoberman, Maxine L Linial, Stephen H Hughes | In vitro fidelity of the prototype pr... | Full length or truncated,Frameshift Error Rate,Nucleotide Substitution Rate,Overall Error Rate,All properties |
| 2007 | Elizabeth J Phillips, Sonia Gutiérrez, Natalie Jahnke, Benita Yip, Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, Julio S G Montaner | Determinants of nevirapine hypersensi... | |
| 2007 | Matthias Götte | Should we include connection domain m... | |
| 2007 | Naoko Iwata, Hiroaki Yoshida, Minoru Tobiume, Fumiko Ono, Takuya Shimazaki, Tetsutaro Sata, Noriko Nakajima | Simian fetal brain progenitor cells f... | |
| 2007 | J Scott Daniels, Robert Espina, Kevin Cao, Haodan Yuan, Jianrong Lin, Sharon Diamond, Barry Johnson, James Rodgers, Shimoga Prakash, Steve Unger, David Christ, Gerald Miwa, Liang-Shang Gan, Abdul Mutlib | Species-specific, P450- and sulfotran... | |
| 2007 | Lei Ji, Fen-Er Chen, Bin Xie, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV activity evalu... | |
| 2007 | Jan Balzarini, Barbara Orzeszko, Jan K Maurin, Andrzej Orzeszko | Synthesis and anti-HIV studies of 2-a... | |
| 2007 | Lei Ji, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV-1 activity eva... | |
| 2007 | Tokumi Maruyama, Yosuke Demizu, Shigetada Kozai, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq | Antiviral activity of 3-(3,5-dimethyl... | |
| 2007 | Sonia de Castro, Graziela Andrei, Robert Snoeck, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez | Novel non-nucleoside human cytomegalo... | |
| 2006 | Jiong Wang, Carrie Dykes, R A Domaoal, Christine E Koval, R A Bambara, Lisa M Demeter | The HIV-1 reverse transcriptase mutan... | |
| 2006 | Tokumi Maruyama, Shigetada Kozai, Yosuke Demizu, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq | Synthesis and anti-HIV-1 and anti-HCM... | |
| 2006 | Monica E Hamburgh, Kenneth A Curr, Melissa Monaghan, Vasudev R Rao, Snehlata Tripathi, Bradley D Preston, Stefan G Sarafianos, Edward Arnold, Thomas Darden, Vinayaka R Prasad | Structural determinants of slippage-m... | |
| 2006 | CF Perno, Valentina Svicher, Dominique Schols, Michela Pollicita, Jan Balzarini, Stefano Aquaro | Therapeutic strategies towards HIV-1 ... | |
| 2006 | Enzo Tramontano | HIV-1 RNase H: recent progress in an ... | |
| 2006 | Zandrea Ambrose, John G Julias, Paul L Boyer, Vineet N Kewalramani, Stephen H Hughes | The level of reverse transcriptase (R... | |
| 2006 | Bo-Liang Deng, Matthew D Cullen, Zhigang Zhou, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman | Synthesis and anti-HIV activity of ne... | |
| 2006 | Klaus Klumpp, Tara Mirzadegan | Recent progress in the design of smal... | |
| 2006 | Nicolas Sluis-Cremer, Noureddine Hamamouch, Ana San Félix, Sonsoles Velazquez, Jan Balzarini, María-José Camarasa | Structure-activity relationships of [... | |
| 2006 | Lei Ji, Fen-Er Chen, Xiao-Qing Feng, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2006 | Varuni K Jamburuthugoda, Pauline Chugh, Baek Kim | Modification of human immunodeficienc... | |
| 2006 | Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Combining mutations in HIV-1 reverse ... | |
| 2006 | Valentina Svicher, Tobias Sing, Maria Mercedes Santoro, Federica Forbici, Fátima Rodríguez-Barrios, Ada Bertoli, Niko Beerenwinkel, Maria Concetta Bellocchi, Federigo Gago, Antonella d'Arminio Monforte, Andrea Antinori, Thomas Lengauer, F Ceccherini-Silberstein, CF Perno | Involvement of novel human immunodefi... | |
| 2006 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, María-Cruz Bonache, Sonia de Castro | TSAO derivatives, inhibitors of HIV-1... | |
| 2006 | Roberto Di Santo, Roberta Costi, Marino Artico, Rino Ragno, Antonio Lavecchia, Ettore Novellino, Enrico Gavuzzo, Francesco La Torre, Roberto Cirilli, Reynel Cancio, Giovanni Maga | Design, synthesis, biological evaluat... | |
| 2006 | Frank Goebel, Alexy Yakovlev, Anton L Pozniak, Elena Vinogradova, Griet Boogaerts, Richard Hoetelmans, Marie-Pierre P De Béthune, Monika Peeters, Brian Woodfall | Short-term antiviral activity of TMC2... | |
| 2006 | Matthias Götte | Effects of nucleotides and nucleotide... | RT,All properties |
| 2006 | Daniel M Himmel, Stefan G Sarafianos, Sanjeewa Dharmasena, Mohammed M Hossain, Kessler McCoy-Simandle, Tatiana Ilina, Arthur D Clark, Jennifer L Knight, John G Julias, Patrick K Clark, Karsten Krogh-Jespersen, Ronald M Levy, Stephen H Hughes, Michael A. Parniak, Edward Arnold | HIV-1 reverse transcriptase structure... | RT,RNase H,All properties |
| 2006 | Dirk Jochmans, Jérôme Deval, Bart Kesteleyn, Herwig Van Marck, Eva Bettens, Inky De Baere, Pascale Dehertogh, Tania Ivens, Marcia Van Ginderen, Bertrand Van Schoubroeck, Maryam Ehteshami, Piet Wigerinck, Matthias Götte, Kurt Hertogs | Indolopyridones inhibit human immunod... | RT,All properties |
| 2006 | Gabriella De Martino, Giuseppe La Regina, Rino Ragno, Antonio Coluccia, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri | Indolyl aryl sulphones as HIV-1 non-n... | |
| 2006 | Najim A Al-Masoudi, Yaseen A Al-Soud, Aris Kalogerakis, Christophe Pannecouque, Erik De Clercq | Nitroimidazoles, part 2: Synthesis, a... | |
| 2006 | Hiroshi Ohrui, Satoru Kohgo, Hiroyuki Hayakawa, Eiichi N Kodama, Masao Matsuoka, Tomohiro Nakata, Hiroyuki Mitsuya | 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosi... | RT,All properties |
| 2006 | Carrie Dykes, Jiong Wang, Xia Jin, Vicente Planelles, Dong Sung An, Amanda Tallo, Yangxin Huang, Hulin Wu, Lisa M Demeter | Evaluation of a multiple-cycle, recom... | |
| 2006 | Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong | Novel nonnucleoside inhibitors that s... | |
| 2006 | Jingshan Ren, Charles E Nichols, Anna Stamp, Phillip P Chamberlain, Robert G Ferris, Kurt L Weaver, Steven A Short, David K Stammers | Structural insights into mechanisms o... | |
| 2006 | Sarit Aviel-Ronen, Chang Qi Zhu, Bradley P Coe, Ni Liu, Spencer K Watson, Wan L Lam, Ming Sound Tsao | Large fragment Bst DNA polymerase for... | |
| 2006 | Carlos Cruchaga, Elena Ansó, Ana Rouzaut, Juan J Martínez-Irujo | Selective excision of chain-terminati... | |
| 2006 | Roberto Di Santo, Roberta Costi, Marino Artico, Gaetano Miele, Antonio Lavecchia, Ettore Novellino, Alberto Bergamini, Reynel Cancio, Giovanni Maga | Arylthiopyrrole (AThP) derivatives as... | |
| 2006 | Antonio Lavecchia, Roberta Costi, Marino Artico, Gaetano Miele, Ettore Novellino, Alberto Bergamini, Emmanuele Crespan, Giovanni Maga, Roberto Di Santo | Arylthiopyrrole (AThP) derivatives as... | |
| 2006 | Paul L Boyer, Stefan G Sarafianos, Patrick K Clark, Edward Arnold, Stephen H Hughes | Why do HIV-1 and HIV-2 use different ... | |
| 2006 | Kirsten L White, James M Chen, Joy Y Feng, Nicolas A Margot, John K Ly, Adrian S Ray, Holly L Macarthur, Martin J McDermott, S Swaminathan, Michael D Miller | The K65R reverse transcriptase mutati... | |
| 2006 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, Federico Gago | Dimerization inhibitors of HIV-1 reve... | |
| 2006 | Christine E Koval, Carrie Dykes, Jiong Wang, Lisa M Demeter | Relative replication fitness of efavi... | |
| 2006 | N Machouf, R Thomas, V K Nguyen, B Trottier, M R Boulassel, Mark A. Wainberg, Jean-Pierre Routy | Effects of drug resistance on viral l... | |
| 2005 | Jan Heeres, Marc R De Jonge, Lucien M H Koymans, Frits F D Daeyaert, Maarten H Vinkers, Koen J A Van Aken, Edward Arnold, Kalyan Das, Amuri Kilonda, Georges J Hoornaert, Frans Compernolle, Marek Cegla, Rasha A Azzam, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Paul A J Janssen | Design, synthesis, and SAR of a novel... | |
| 2005 | Kalyan Das, Paul J Lewi, Stephen H Hughes, Edward Arnold | Crystallography and the design of ant... | |
| 2005 | Yaofeng Zhao, Yang Jin, Jing-Houng Wang, Rui-Rui Wang, Liu-Meng Yang, Wen-Hui Lee, Yong-Tang Zheng, Yongqing Zhang | A novel heme-containing protein with ... | |
| 2005 | Darwin J Operario, Holly M Reynolds, Baek Kim | Comparison of DNA polymerase activiti... | Molecular Weight,Overall Error Rate,All properties |
| 2005 | Dan Turner, Bluma G Brenner, Daniela D Moisi, Chen Liang, Mark A. Wainberg | Substitutions in the Reverse Transcri... | |
| 2005 | Jan Balzarini, Miguel Stevens, Erik De Clercq, Dominique Schols, Christophe Pannecouque | Pyridine N-oxide derivatives: unusual... | |
| 2005 | Ben Berkhout, Anthony de Ronde, Lia van der Hoek | Aggressive HIV-1? | |
| 2005 | Luis R Miranda, Matthias Götte, Fei Liang, Daniel R Kuritzkes | The L74V mutation in human immunodefi... | |
| 2005 | Fátima Rodríguez-Barrios, Jan Balzarini, Federico Gago | The molecular basis of resilience to ... | |
| 2005 | Joeri Auwerx, Fátima Rodríguez-Barrios, F Ceccherini-Silberstein, Ana San-Félix, Sonsoles Velázquez, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini | The role of Thr139 in the human immun... | |
| 2005 | Ronald B Geskus, Laurence Meyer, Jean-Baptiste Hubert, Hanneke Schuitemaker, Ben Berkhout, Christine Rouzioux, Ioannis D Theodorou, Jean-François Delfraissy, Maria Prins, Roel A Coutinho | Causal pathways of the effects of age... | |
| 2005 | Mark A. Wainberg, James P C Sawyer, Julio S G Montaner, Robert L Murphy, Daniel R Kuritzkes, Francois Raffi | Challenges for the clinical developme... | |
| 2005 | Daniel M Himmel, Kalyan Das, Arthur D Clark, Stephen H Hughes, Abdellah Benjahad, Said Oumouch, Jérôme Guillemont, Sophie Coupa, Alain Poncelet, Imre Csoka, Christophe Meyer, Koen Andries, Chi Hung Nguyen, David S Grierson, Edward Arnold | Crystal structures for HIV-1 reverse ... | RT,Associated condition,All properties |
| 2005 | Andrew R Zolopa, Laura C Lazzeroni, Alex Rinehart, Françoise Brun Vezinet, François Clavel, Ann Collier, Brian Conway, Roy M Gulick, Mark Holodniy, CF Perno, Robert W Shafer, Douglas D Richman, Mark A. Wainberg, Daniel R Kuritzkes | Accuracy, precision, and consistency ... | |
| 2005 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez | TSAO derivatives the first non-peptid... | |
| 2005 | Nicolas Sluis-Cremer, Dominique Arion, Urvi Parikh, Dianna Koontz, Raymond F Schinazi, John W Mellors, Michael A. Parniak | The 3'-azido group is not the primary... | |
| 2005 | Melaku Adal, Workenesh Ayele, Dawit Wolday, Kifle Dagne, Tsehaynesh Messele, Tesfaye Tilahun, Ben Berkhout, Shlomo Mayaan, Georgios Pollakis, Wendelien Dorigo-Zetsma | Evidence of genetic variability of hu... | |
| 2005 | Joël Didierjean, Catherine Isel, Flore Querré, Jean-François Mouscadet, Anne-Marie Aubertin, Jean-Yves Valnot, Serge R Piettre, Roland Marquet | Inhibition of human immunodeficiency ... | |
| 2005 | Johan Vingerhoets, Hilde Azijn, Els Fransen, Inky De Baere, Liesbet Smeulders, Dirk Jochmans, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune | TMC125 displays a high genetic barrie... | |
| 2005 | Lia van der Hoek, Nicole Back, Maarten F Jebbink, Anthony de Ronde, Margreet Bakker, Suzanne Jurriaans, Peter Reiss, Neil Parkin, Ben Berkhout | Increased multinucleoside drug resist... | |
| 2005 | Fernando A Frankel, Bruno Marchand, Dan Turner, Matthias Götte, Mark A. Wainberg | Impaired rescue of chain-terminated D... | |
| 2005 | Dan Turner, Bluma G Brenner, Daniela Mosis, Chen Liang, Mark A. Wainberg | Substitutions in the reverse transcri... | |
| 2005 | Kirsten L White, Nicolas A Margot, John K Ly, James M Chen, Adrian S Ray, Martina Pavelko, Ruth Wang, Martin J McDermott, S Swaminathan, Michael D Miller | A combination of decreased NRTI incor... | |
| 2005 | Daniel Summerer, Andreas Marx | 4'C-ethynyl-thymidine acts as a chain... | |
| 2005 | Tongfei Wu, Matheus Froeyen, Veerle Kempeneers, Christophe Pannecouque, Jing Wang, Roger Busson, Erik De Clercq, Piet Herdewijn | Deoxythreosyl phosphonate nucleosides... | |
| 2005 | Pia S Kivelä, Anneke Krol, Mika O Salminen, Ronald B Geskus, Jukka I Suni, Veli-Jukka Anttila, Kirsi Liitsola, Veera Zetterberg, Frank Miedema, Ben Berkhout, Roel A Coutinho, Matti A Ristola | High plasma HIV load in the CRF01-AE ... | |
| 2005 | Hong Li, Zhengqiang Wang, Wei-guo Cui, Yan Liang, Tian-yi Xin, Jinming Li | [Study on adherence and interrelated ... | |
| 2005 | Scott R Budihas, Inna Gorshkova, Sergei A Gaidamakov, Antony Wamiru, Marion K Bona, Michael A. Parniak, Robert J Crouch, James B McMahon, John A Beutler, Stuart F J Le Grice | Selective inhibition of HIV-1 reverse... | |
| 2005 | Albert Nguyen Van Nhien, Cyrille Tomassi, Christophe Len, José Luis Marco-Contelles, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Denis Postel | First synthesis and evaluation of the... | |
| 2005 | F Ceccherini-Silberstein, Federico Gago, Maria Mercedes Santoro, Caterina Gori, Valentina Svicher, Fátima Rodríguez-Barrios, Roberta d'Arrigo, Massimo Ciccozzi, Ada Bertoli, Antonella d'Arminio Monforte, Jan Balzarini, Andrea Antinori, CF Perno | High sequence conservation of human i... | |
| 2005 | Hong Zang, Thomas M Harris, F Peter Guengerich | Kinetics of nucleotide incorporation ... | |
| 2005 | Ariel Fernández, Dan S Tawfik, Ben Berkhout, Rogier W Sanders, Andrzej Kloczkowski, Taner Sen, Bob Jernigan | Protein promiscuity: drug resistance ... | |
| 2005 | Hong Zang, Thomas M Harris, F Peter Guengerich | Kinetics of nucleotide incorporation ... | |
| 2005 | Cathryn A Shaw-Reid, Bradley Feuston, Vandna Munshi, Krista Getty, Julie Krueger, Daria J Hazuda, Michael A. Parniak, Michael D Miller, Dale Lewis | Dissecting the effects of DNA polymer... | |
| 2005 | Jan Balzarini, Kristel Van Laethem, Sigrid Hatse, Matheus Froeyen, Els Van Damme, Anders Bolmstedt, Willy Peumans, Erik De Clercq, Dominique Schols | Marked depletion of glycosylation sit... | |
| 2005 | Alok Mulky, Stefan G Sarafianos, Yujiang Jia, Edward Arnold, John C Kappes | Identification of amino acid residues... | |
| 2005 | Guang-Fu Sun, Xu-Xiang Chen, Fen-Er Chen, Yue-Ping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse-transcrip... | |
| 2005 | Ariel Roldan, Otis U Warren, Rodney S Russell, Chen Liang, Mark A. Wainberg | A HIV-1 minimal gag protein is superi... | |
| 2005 | Paul A J Janssen, Paul J Lewi, Edward Arnold, Frits F D Daeyaert, Marc R De Jonge, Jan Heeres, Luc Koymans, Maarten H Vinkers, Jérôme Guillemont, Elisabeth Pasquier, Michael Kukla, Don Ludovici, Koen Andries, Marie-Pierre P De Béthune, Rudi Pauwels, Kalyan Das, Arthur D Clark, Yulia Volovik Frenkel, Stephen H Hughes, Bart Medaer, Fons De Knaep, Hilde Bohets, Fred De Clerck, Ann Lampo, Peter Williams, Paul Stoffels | In search of a novel anti-HIV drug: m... | |
| 2005 | Michael E Ignatov, Anthony J Berdis, Stuart F J Le Grice, Mary D Barkley | Attenuation of DNA replication by HIV... | |
| 2005 | Natalia A Lebedeva, T A Seredina, V N Silnikov, T V Abramova, A S Levina, Svetlana N Khodyreva, Nadejda I Rechkunova, Olga I Lavrik | Analysis of interactions of DNA polym... | |
| 2005 | Jan Balzarini, Joeri Auwerx, Fátima Rodríguez-Barrios, Allel Chedad, Viktor Farkas, F Ceccherini-Silberstein, Carlos García-Aparicio, Sonsoles Velázquez, Erik De Clercq, CF Perno, María-José Camarasa, Federico Gago | The amino acid Asn136 in HIV-1 revers... | |
| 2005 | Michael E Abram, Michael A. Parniak | Virion instability of human immunodef... | |
| 2005 | Rienk E Jeeninga, Barbara Jan, Birgit van der Linden, Henk van den Berg, Ben Berkhout | Construction of a minimal HIV-1 varia... | |
| 2005 | Junmei Wang, Xinshan Kang, Irwin D Kuntz, Peter A Kollman | Hierarchical database screenings for ... | |
| 2005 | Joeri Auwerx, Joke Van Nieuwenhove, Fátima Rodríguez-Barrios, Sonia de Castro, Sonsoles Velázquez, F Ceccherini-Silberstein, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini | The N137 and P140 amino acids in the ... | |
| 2005 | Micha Nethe, Ben Berkhout, Antoinette C van der Kuyl | Retroviral superinfection resistance. | |
| 2005 | Erik De Clercq | Emerging anti-HIV drugs. | |
| 2005 | Emmanuele Crespan, Giada A Locatelli, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Drug resistance mutations in the nucl... | |
| 2005 | Antonello Mai, Marino Artico, Rino Ragno, Gianluca Sbardella, Silvio Massa, Chiara Musiu, Massimo Mura, Flavia Marturana, Alessandra Cadeddu, Giovanni Maga, Paolo La Colla | 5-Alkyl-2-alkylamino-6-(2,6-difluorop... | |
| 2005 | Gabriella De Martino, Giuseppe La Regina, Alessandra Di Pasquali, Rino Ragno, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri | Novel 1-[2-(diarylmethoxy)ethyl]-2-me... | |
| 2005 | Bo-Liang Deng, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman | Synthesis, anti-HIV activity, and met... | |
| 2005 | Myriam Witvrouw, Valery Fikkert, Anke Hantson, Christophe Pannecouque, Barry R O'keefe, James McMahon, Leonidas Stamatatos, Erik De Clercq, Anders Bolmstedt | Resistance of human immunodeficiency ... | |
| 2005 | Emmanuele Crespan, Samantha Zanoli, Anastasiya Khandazhinskaya, Igor V Shevelev, Maxim Jasko, Ludmila Alexandrova, Marina Kukhanova, Giuseppina Blanca, Giuseppe Villani, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Incorporation of non-nucleoside triph... | |
| 2005 | Caterina Fattorusso, Sandra Gemma, Stefania Butini, Paul Huleatt, Bruno Catalanotti, Marco Persico, Meri De Angelis, Isabella Fiorini, Vito Nacci, Anna Ramunno, Manuela Rodriquez, Giovanni Greco, Ettore Novellino, Alberto Bergamini, Stefano Marini, Massimo Coletta, Giovanni Maga, Silvio Spadari, Giuseppe Campiani | Specific targeting highly conserved r... | |
| 2005 | Guang-Fu Sun, Yun-Yan Kuang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Non-nucleoside HIV reverse transcript... | |
| 2005 | Abdellah Benjahad, Martine Croisy, Claude Monneret, Emile Bisagni, Dominique Mabire, Sophie Coupa, Alain Poncelet, Imre Csoka, Jérôme Guillemont, Christophe Meyer, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Daniel M Himmel, Kalyan Das, Edward Arnold, Chi Hung Nguyen, David S Grierson | 4-Benzyl and 4-benzoyl-3-dimethylamin... | |
| 2004 | George A Freeman, C Webster Andrews Iii, Andrew L Hopkins, Gina S Lowell, Lee T Schaller, Jill R Cowan, Stephen S Gonzales, George W Koszalka, Richard J Hazen, Lawrence R Boone, Rob G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, David J Reynolds, John Milton, Jingshan Ren, David I Stuart, David K Stammers, Joseph H Chan | Design of non-nucleoside inhibitors o... | RT,Associated condition,All properties |
| 2004 | Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Marco Petrella, Mark A. Wainberg | Rationale for maintenance of the M184... | |
| 2004 | Jérôme Deval, Kirsten L White, Michael D Miller, Neil T Parkin, Jérôme Courcambeck, Philippe Halfon, Boulbaba Selmi, Joëlle Boretto, Bruno Canard | Mechanistic basis for reduced viral a... | |
| 2004 | Jérôme Deval, Jean-Marc Navarro, Boulbaba Selmi, Jérôme Courcambeck, Joëlle Boretto, Philippe Halfon, Sarah Garrido-Urbani, Josephine Sire, Bruno Canard | A loss of viral replicative capacity ... | |
| 2004 | Paul L Boyer, Tomozumi Imamichi, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Effects of the Delta67 complex of mut... | |
| 2004 | Jeong-Yun Choi, F Peter Guengerich | Analysis of the effect of bulk at N2-... | |
| 2004 | Matthias Götte | Inhibition of HIV-1 reverse transcrip... | |
| 2004 | Erik De Clercq | Antiviral drugs in current clinical use. | |
| 2004 | Bruno Marchand, Matthias Götte | Impact of the translocational equilib... | |
| 2004 | Eisuke Murakami, Adrian S Ray, Raymond F Schinazi, Karen S Anderson | Investigating the effects of stereoch... | |
| 2004 | Joeri Auwerx, Miguel Stevens, An R Van Rompay, Louise E Bird, Jingshan Ren, Erik De Clercq, Bo Oberg, David K Stammers, Anna Karlsson, Jan Balzarini | The phenylmethylthiazolylthiourea non... | |
| 2004 | Kenji Kitano, Satoru Kohgo, Kohei Yamada, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui | Attempt to reduce cytotoxicity by syn... | |
| 2004 | Kalyan Das, Arthur D Clark, Paul J Lewi, Jan Heeres, Marc R De Jonge, Lucien M H Koymans, H Maarten Vinkers, Frederik Daeyaert, Donald W Ludovici, Michael J Kukla, Bart De Corte, Robert W Kavash, Chih Y Ho, Hong Ye, Mark A Lichtenstein, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Paul L Boyer, Patrick K Clark, Stephen H Hughes, Paul A J Janssen, Edward Arnold | Roles of conformational and positiona... | |
| 2004 | Giada A Locatelli, Giuseppe Campiani, Reynel Cancio, Elena Morelli, Anna Ramunno, Sandra Gemma, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Effects of drug resistance mutations ... | |
| 2004 | Reynel Cancio, Silvio Spadari, Giovanni Maga | Vif is an auxiliary factor of the HIV... | |
| 2004 | Giada A Locatelli, Reynel Cancio, Silvio Spadari, Giovanni Maga | HIV-1 reverse transcriptase inhibitor... | |
| 2004 | Stefania Paolucci, Fausto Baldanti, Giovanni Maga, Reynel Cancio, Maurizio Zazzi, Maurizio Zavattoni, Antonella Chiesa, Silvio Spadari, Giuseppe Gerna | Gln145Met/Leu changes in human immuno... | |
| 2004 | Alok Mulky, Stefan G Sarafianos, Edward Arnold, Xiaoming Wu, John C Kappes | Subunit-specific analysis of the huma... | |
| 2004 | Elena N Peletskaya, Alex A Kogon, Steven Tuske, Edward Arnold, Stephen H Hughes | Nonnucleoside inhibitor binding affec... | RT,Associated condition,All properties |
| 2004 | George R Painter, Merrick R Almond, Shuli Mao, Dennis C Liotta | Biochemical and mechanistic basis for... | RT,Associated condition,All properties |
| 2004 | Lisa F Rezende, Vinayaka R Prasad | Nucleoside-analog resistance mutation... | RT,Associated condition,All properties |
| 2004 | A Michael Sismour, Stefan Lutz, Jeong-Ho Park, Michael J Lutz, Paul L Boyer, Stephen H Hughes, Steven A Benner | PCR amplification of DNA containing n... | |
| 2004 | Koen Andries, Hilde Azijn, Theo Thielemans, Donald W Ludovici, Michael Kukla, Jan Heeres, Paul A J Janssen, Bart De Corte, Johan Vingerhoets, Rudi Pauwels, Marie-Pierre P De Béthune | TMC125, a novel next-generation nonnu... | RT,Associated condition,All properties |
| 2004 | John G Julias, Paul L Boyer, Mary Jane McWilliams, W Gregory Alvord, Stephen H Hughes | Mutations at position 184 of human im... | |
| 2004 | Stefan G Sarafianos, Kalyan Das, Stephen H Hughes, Edward Arnold | Taking aim at a moving target: design... | |
| 2004 | Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, David K Stammers | Crystal structures of HIV-1 reverse t... | |
| 2004 | King C Chan, Scott R Budihas, Stuart F J Le Grice, Michael A. Parniak, Robert J Crouch, Sergei A Gaidamakov, Haleem J Isaaq, Antony Wamiru, James B McMahon, John A Beutler | A capillary electrophoretic assay for... | |
| 2004 | Kirsten L White, James M Chen, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Lisa K Naeger, S Swaminathan, Michael D Miller | Molecular mechanisms of tenofovir res... | |
| 2004 | Rachelle J Bienstock, Willliam C Copeland | Molecular insights into NRTI inhibiti... | |
| 2004 | Satoru Kohgo, Kohei Yamada, Kenji Kitano, Yuko Iwai, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui | Design, efficient synthesis, and anti... | |
| 2004 | Esther W Hou, Rajendra Prasad, William A Beard, Samuel H Wilson | High-level expression and purificatio... | |
| 2004 | Claudia M D'Abramo, Luciano Cellai, Matthias Götte | Excision of incorporated nucleotide a... | |
| 2004 | George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Kalavathy Sitaraman, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice | Site- and subunit-specific incorporat... | |
| 2004 | Elisabetta Bulgheroni, Francesco Croce, Paola Citterio, Ottavia Viganò, Raffaella Visonà, Eugenio Sala, Massimo Galli, Stefano Rusconi | Unusual codon 69 insertions: influenc... | |
| 2004 | Andrew L Hopkins, Jingshan Ren, John Milton, Richard J Hazen, Joseph H Chan, David I Stuart, David K Stammers | Design of non-nucleoside inhibitors o... | RT,Associated condition,All properties |
| 2004 | Joy Y Feng, Eisuke Murakami, Suzana M Zorca, Allison A Johnson, Kenneth A Johnson, Raymond F Schinazi, Phillip A Furman, Karen S Anderson | Relationship between antiviral activi... | |
| 2004 | Nicolas Sluis-Cremer, Dominique Arion, Michael E Abram, Michael A. Parniak | Proteolytic processing of an HIV-1 po... | |
| 2004 | Joeri Auwerx, Robert Esnouf, Erik De Clercq, Jan Balzarini | Susceptibility of feline immunodefici... | |
| 2004 | Julie Qi Hang, Surendran Rajendran, Yanli Yang, Yingqian Li, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin, Klaus Klumpp | Activity of the isolated HIV RNase H ... | |
| 2004 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Effects of mutations in the G tract o... | |
| 2004 | Peter R Meyer, Anthony J Smith, Suzanne E Matsuura, Walter A Scott | Effects of primer-template sequence o... | |
| 2004 | Dan Turner, Bluma G Brenner, Mark A. Wainberg | Relationships among various nucleosid... | |
| 2004 | Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà | Synthesis of new 2,3-diaryl-1,3-thiaz... | |
| 2004 | Erik De Clercq | Non-nucleoside reverse transcriptase ... | |
| 2004 | Jan Balzarini | Current status of the non-nucleoside ... | |
| 2004 | María-José Camarasa, Ana San-Félix, Sonsoles Velázquez, María-Jesús Pérez-Pérez, Federico Gago, Jan Balzarini | TSAO compounds: the comprehensive sto... | |
| 2004 | CF Perno, Emanuela Balestra, M Francesconi, D Abdelahad, Raffaele Caliò, Jan Balzarini, Stefano Aquaro | Antiviral profile of HIV inhibitors i... | |
| 2004 | Yanping He, Fener Chen, Guangfu Sun, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | 5-Alkyl-2-[(aryl and alkyloxylcarbony... | |
| 2004 | Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna-Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà | 2-(2,6-Dihalophenyl)-3-(pyrimidin-2-y... | |
| 2004 | Yanping He, Fener Chen, Xiongjie Yu, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse transcrip... | |
| 2004 | Myriam Witvrouw, Bénédicte Van Maele, J Vercammen, Anke Hantson, Y Engelborghs, Erik De Clercq, Christophe Pannecouque, Zeger Debyser | Novel inhibitors of HIV-1 integration. | |
| 2004 | Maximilian A Silvestri, Muthukaman Nagarajan, Erik De Clercq, Christophe Pannecouque, Mark Cushman | Design, synthesis, anti-HIV activitie... | |
| 2004 | Maqbool A Siddiqui, Stephen H Hughes, Paul L Boyer, Hiroyuki Mitsuya, Que N Van, Clifford George, Stefan G Sarafinanos, Victor E Marquez | A 4'-C-ethynyl-2',3'-dideoxynucleosid... | |
| 2004 | Louise Z Wang, George L Kenyon, Kenneth A Johnson | Novel mechanism of inhibition of HIV-... | |
| 2004 | Stefan G Sarafianos, Stephen H Hughes, Edward Arnold | Designing anti-AIDS drugs targeting t... | |
| 2004 | Paul J Lewi, Edward Arnold, Koen Andries, Hilde Bohets, Herman Borghys, Arthur D Clark, Frits F D Daeyaert, Kalyan Das, Marie-Pierre P De Béthune, Marc R De Jonge, Jan Heeres, Luc Koymans, Jos Leempoels, Jef Peeters, Philip Timmerman, Walter Van den Broeck, Frédéric Vanhoutte, Gerben Van't Klooster, Maarten H Vinkers, Yulia Volovik, Paul A J Janssen | Correlations between factors determin... | |
| 2004 | Dan Turner, Bluma G Brenner, Daniela D Moisi, Mervi Detorio, Raymond Cesaire, Takashi Kurimura, Haruyo Mori, Max Essex, Shlomo Maayan, Mark A. Wainberg | Nucleotide and amino acid polymorphis... | |
| 2004 | Michael B Doughty, Karam Aboudehen, Garland Anderson, Ke Li, Bob Moore, Tina Poolson | Side-chain conformational restriction... | |
| 2004 | Florence Doualla-Bell, Simane Gaseitsiwe, Thumbi Ndungú, Musetsanagepe Modukanele, Trevor Peter, Vladimir Novitsky, Ndwapi Ndwapi, Gaolathe Tendani, Ava Avalos, William Wester, Hermann Bussmann, Peter Cardiello, Richard G Marlink, Howard Moffat, Ibou Thior, Mark A. Wainberg, Max Essex | Mutations and polymorphisms associate... | |
| 2004 | Mark A. Wainberg | The impact of the M184V substitution ... | |
| 2004 | Dan Turner, Ariel Roldan, Bluma G Brenner, Daniela D Moisi, Jean-Pierre Routy, Mark A. Wainberg | Variability in the PR and RT genes of... | |
| 2004 | Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Zeev Rosberger, Michel Roger, Mark A. Wainberg | Diminished representation of HIV-1 va... | |
| 2004 | Steve Tuske, Stefan G Sarafianos, Arthur D Clark, Jianping Ding, Lisa K Naeger, Kirsten L White, Michael D Miller, Craig S Gibbs, Paul L Boyer, Patrick K Clark, Gang Wang, Barbara L Gaffney, Roger A Jones, Donald M Jerina, Stephen H Hughes, Edward Arnold | Structures of HIV-1 RT-DNA complexes ... | |
| 2004 | Zandrea Ambrose, Valerie Boltz, Sarah Palmer, John M Coffin, Stephen H Hughes, Vineet N Kewalramani | In vitro characterization of a simian... | |
| 2004 | Debanu Das, Millie M Georgiadis | The crystal structure of the monomeri... | |
| 2003 | Giuseppina Blanca, Igor V Shevelev, Kristijan Ramadan, Giuseppe Villani, Silvio Spadari, Ulrich Hübscher, Giovanni Maga | Human DNA polymerase lambda diverged ... | |
| 2003 | Sanjay U C Sankatsing, Gerrit J Weverling, Monika Peeters, Gerben van't Klooster, Boris Gruzdev, Aza Rakhmanova, Sven A Danner, Suzanne Jurriaans, Jan M Prins, Joep M A Lange | TMC125 exerts similar initial antivir... | |
| 2003 | Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, Jingshan Ren, David I Stuart, David K Stammers | Cloning, expression, purification, an... | |
| 2003 | Eisuke Murakami, Joy Y Feng, Harold R Lee, Jeremiah Hanes, Kenneth A Johnson, Karen S Anderson | Characterization of novel reverse tra... | |
| 2003 | Harold R Lee, Jeremiah Hanes, Kenneth A Johnson | Toxicity of nucleoside analogues used... | |
| 2003 | Joel E Gallant, Peter Z Gerondelis, Mark A. Wainberg, Nancy S Shulman, Richard H Haubrich, Marty St Clair, Ernest R Lanier, Nicholas S Hellmann, Douglas D Richman | Nucleoside and nucleotide analogue re... | RT,Associated condition,All properties |
| 2003 | Romas Geleziunas, Karen Gallagher, Hangchun Zhang, Lee Bacheler, Sena Garber, Jing-Tao Wu, Guoen Shi, Michael J Otto, Raymond F Schinazi, Susan Erickson-Viitanen | HIV-1 resistance profile of the novel... | |
| 2003 | J Gerardo García-Lerma, Hamish MacInnes, Diane Bennett, Patrick Reid, Soumya Nidtha, Hillard Weinstock, Jonathan E Kaplan, Walid Heneine | A novel genetic pathway of human immu... | |
| 2003 | William A Beard, Samuel H Wilson | Structural insights into the origins ... | |
| 2003 | Maria Letizia Barreca, Alba Chimirri, Erik De Clercq, Laura De Luca, Anna-Maria Monforte, Pietro Monforte, Angela Rao, Maria Zappalà | Anti-HIV agents: design and discovery... | |
| 2003 | Qian Zhao, Hong Lu, Dominique Schols, Erik De Clercq, Shibo Jiang | Development of a cell-based enzyme-li... | |
| 2003 | Myriam Witvrouw, Christophe Pannecouque, Valery Fikkert, Anke Hantson, Barbara Van Remoortel, Marjan Hezareh, Erik De Clercq, Stephen J Brown | Potent and selective inhibition of HI... | |
| 2003 | Adrian S Ray, Raymond F Schinazi, Eisuke Murakami, Aravind Basavapathruni, Junxing Shi, Suzana M Zorca, Chung K Chu, Karen S Anderson | Probing the mechanistic consequences ... | RT,Associated condition,All properties |
| 2003 | Evguenia S Svarovskaia, Sara R Cheslock, Wen-Hui Zhang, Wei-Shau Hu, Vinay K Pathak | Retroviral mutation rates and reverse... | |
| 2003 | Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Mutations in the 5' end of the human ... | |
| 2003 | Klaus Klumpp, Julie Qi Hang, Surendran Rajendran, Yanli Yang, Andre Derosier, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin | Two-metal ion mechanism of RNA cleava... | |
| 2003 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Mutation of amino acids in the connec... | |
| 2003 | Bruno Marchand, Matthias Götte | Site-specific footprinting reveals di... | |
| 2003 | Mélanie Girouard, Karidia Diallo, Bruno Marchand, Suzanne McCormick, Matthias Götte | Mutations E44D and V118I in the rever... | |
| 2003 | Peter R Meyer, Johan Lennerstrand, Suzanne E Matsuura, Brendan A Larder, Walter A Scott | Effects of dipeptide insertions betwe... | |
| 2003 | Adrian S Ray, Eisuke Murakami, Aravind Basavapathruni, Joseph A Vaccaro, Dagny Ulrich, Chung K Chu, Raymond F Schinazi, Karen S Anderson | Probing the molecular mechanisms of A... | |
| 2003 | Boulbaba Selmi, Jerome Deval, Karine Alvarez, Joelle Boretto, Simon Sarfati, Catherine Guerreiro, Bruno Canard | The Y181C substitution in 3'-azido-3'... | |
| 2003 | Martin Stürmer, Schlomo Staszewski, Hans-Wilhelm Doerr, Brendan A Larder, Stuart Bloor, Kurt Hertogs | Correlation of phenotypic zidovudine ... | |
| 2003 | Irene M Lagoja, Christophe Pannecouque, Arthur Van Aerschot, Myriam Witvrouw, Zeger Debyser, Jan Balzarini, Piet Herdewijn, Erik De Clercq | N-aminoimidazole derivatives inhibiti... | |
| 2003 | Ge Meng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse transcrip... | |
| 2003 | Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini | Inhibition of human immunodeficiency ... | |
| 2003 | Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini | Novel human immunodeficiency virus (H... | |
| 2003 | Jaroslaw Poznanski, Maria Bretner, Tadeusz Kulikowski, Jan Balzarini, Arthur Van Aerschot, Erik De Clercq | Synthesis, solution conformation and ... | |
| 2003 | Jan Balzarini, Erik De Clercq, Beata Kaminska, Andrzej Orzeszko | Synthesis and antiviral activity of s... | |
| 2003 | Peter R Meyer, Suzanne E Matsuura, Dianna Zonarich, Rahul R Chopra, Eric Pendarvis, Holly Z Bazmi, John W Mellors, Walter A Scott | Relationship between 3'-azido-3'-deox... | |
| 2003 | María-Cruz Bonache, Cristina Chamorro, Esther Lobatón, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, Ana San-Félix | Structure-activity relationship studi... | |
| 2003 | Koyo Ariyoshi, Masakazu Matsuda, Hideka Miura, Sachiko Tateishi, Kaneo Yamada, Wataru Sugiura | Patterns of point mutations associate... | |
| 2003 | Tokumi Maruyama, Shigetada Kozai, Tetsuo Yamasaki, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoeck, Graciella Andrei, Erik De Clercq | Synthesis and antiviral activity of 1... | |
| 2003 | Angelo Ranise, Andrea Spallarossa, Silvia Schenone, Olga Bruno, Francesco Bondavalli, Laura Vargiu, Tiziana Marceddu, Massimo Mura, Paolo La Colla, Alessandra Pani | Design, synthesis, SAR, and molecular... | |
| 2003 | Bluma G Brenner, Dan Turner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Mauricio Carobene, Richard G Marlink, Jonathan Schapiro, Michel Roger, Mark A. Wainberg | A V106M mutation in HIV-1 clade C vir... | |
| 2003 | Wei Huang, Andrea Gamarnik, Kay Limoli, Christos J Petropoulos, Jeannette M Whitcomb | Amino acid substitutions at position ... | |
| 2003 | Yongseok Choi, Clifford George, Maria J Comin, Joseph J Barchi, Hak Sung Kim, Kenneth A Jacobson, Jan Balzarini, Hiroyuki Mitsuya, Paul L Boyer, Stephen H Hughes, Victor E Marquez | A conformationally locked analogue of... | |
| 2003 | Marie-Pierre Golinelli, Stephen H Hughes | Secondary structure in the nucleic ac... | |
| 2003 | Karidia Diallo, Bluma G Brenner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Matthias Götte, Mark A. Wainberg | The M184V substitution in human immun... | |
| 2003 | Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg | Negative effect of the M184V mutation... | |
| 2003 | Karidia Diallo, Bruno Marchand, Xin Wei, Luciano Cellai, Matthias Götte, Mark A. Wainberg | Diminished RNA primer usage associate... | |
| 2003 | Nicolas Sluis-Cremer, Ellis Kempner, Michael A. Parniak | Structure-activity relationships in H... | |
| 2003 | Michael A. Parniak, Kyung-Lyum Min, Scott R Budihas, Stuart F J Le Grice, John A Beutler | A fluorescence-based high-throughput ... | |
| 2003 | Stefania Paolucci, Fausto Baldanti, Marco Tinelli, Giovanni Maga, Giuseppe Gerna | Detection of a new HIV-1 reverse tran... | |
| 2003 | Giuseppina Blanca, Fausto Baldanti, Stefania Paolucci, Alexander Yu Skoblov, Lyubov Victorova, Ulrich Hübscher, Giuseppe Gerna, Silvio Spadari, Giovanni Maga | Nevirapine resistance mutation at cod... | |
| 2003 | Yudong Quan, Bluma G Brenner, Maureen Oliveira, Mark A. Wainberg | Lamivudine can exert a modest antivir... | |
| 2003 | Marilyn B Kroeger Smith, Sandra Ruby, Stanislav Horouzhenko, Bryan Buckingham, Julia Richardson, Ina Puleri, Emily Potts, William L Jorgensen, Edward Arnold, Weiming Zhang, Stephen H Hughes, Christopher J Michejda, Richard H Smith | HIV-1 reverse transcriptase variants:... | |
| 2003 | Lingling Shen, Jianhua Shen, Xiaomin Luo, Feng Cheng, Yechun Xu, Kaixian Chen, Edward Arnold, Jianping Ding, Hualiang Jiang | Steered molecular dynamics simulation... | |
| 2003 | Marilyn B Kroeger Smith, Brian M Hose, Arie Hawkins, James Lipchock, David W Farnsworth, Robert C Rizzo, Julian Tirado-Rives, Edward Arnold, Weiming Zhang, Stephen H Hughes, William L Jorgensen, Christopher J Michejda, Richard H Smith | Molecular modeling calculations of HI... | |
| 2003 | Cathryn A Shaw-Reid, Vandna Munshi, Pia Graham, Abigail Wolfe, Marc Witmer, Renee Danzeisen, David B Olsen, Steven S Carroll, Mark Embrey, John S Wai, Michael D Miller, James L Cole, Daria J Hazuda | Inhibition of HIV-1 ribonuclease H by... | |
| 2003 | Susan E Lim, Mikhail V Ponamarev, Matthew J Longley, William C Copeland | Structural determinants in human DNA ... | |
| 2003 | Marie L Coté, Mark Pflomm, Millie M Georgiadis | Staying straight with A-tracts: a DNA... | |
| 2002 | Qingli Shi, Kamalendra Singh, Aashish Srivastava, Neerja Kaushik, Mukund J Modak | Lysine 152 of MuLV reverse transcript... | |
| 2002 | Dominique Arion, Nicolas Sluis-Cremer, Kyung-Lyum Min, Michael E Abram, Ronald S Fletcher, Michael A. Parniak | Mutational analysis of Tyr-501 of HIV... | |
| 2002 | Laurent Andréoletti, Laurence Weiss, Ali Si-Mohamed, Christophe Piketty, Thierry Prazuck, Gérard Calamy, Jean-Elie Malkin, Mathieu Matta, François-Xavier Mbopi-Kéou, François Clavel, Michel D Kazatchkine, Laurent Bélec | Multidrug-resistant HIV-1 RNA and pro... | |
| 2002 | Brigitte Montes, Michel Segondy | Prevalence of the mutational pattern ... | |
| 2002 | Kirsten L White, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Michael D Miller, Lisa K Naeger | Molecular mechanisms of resistance to... | |
| 2002 | Stefan G Sarafianos, Arthur D Clark, Kalyan Das, Steve Tuske, Jens J Birktoft, Palanichamy Ilankumaran, Andagar R Ramesha, Jane M Sayer, Donald M Jerina, Paul L Boyer, Stephen H Hughes, Edward Arnold | Structures of HIV-1 reverse transcrip... | |
| 2002 | A Geoffrey Skillman, Karl W Maurer, Diana C Roe, Margaret J Stauber, Dolan Eargle, Todd J A Ewing, Angelika Muscate, Elisabeth Davioud-Charvet, Maxine V Medaglia, Robert J Fisher, Edward Arnold, Hong Qiang Gao, Robert W Buckheit, Paul L Boyer, Stephen H Hughes, Irwin D Kuntz, George L Kenyon | A novel mechanism for inhibition of H... | |
| 2002 | Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg | Co-receptor usage and HIV-1 intra-cla... | |
| 2002 | Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg | Polymorphisms of cytotoxic T-lymphocy... | |
| 2002 | Bluma G Brenner, Dan Turner, Mark A. Wainberg | HIV-1 drug resistance: can we overcome? | |
| 2002 | Christopher J Hollowood, Steven V Ley, Shigeo Yamanoi | Synthesis of taurospongin A: a potent... | |
| 2002 | Erik De Clercq | New anti-HIV agents and targets. | |
| 2002 | Jimmy Lindberg, Snaevar Sigurdsson, Seved Löwgren, Hans O Andersson, Christer Sahlberg, Rolf Noréen, Kerstin Fridborg, Haijiang Zhang, Torsten Unge | Structural basis for the inhibitory e... | |
| 2002 | Erik De Clercq | Highlights in the development of new ... | |
| 2002 | N McLellan, Xin Wei, Bruno Marchand, Mark A. Wainberg, Matthias Götte | Nonradioactive detection of retrovira... | |
| 2002 | Lisa K Naeger, Nicolas A Margot, Michael D Miller | ATP-dependent removal of nucleoside r... | |
| 2002 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Mutations in the RNase H domain of HI... | |
| 2002 | L Menéndez-Arias | Molecular basis of fidelity of DNA sy... | |
| 2002 | Michael Strerath, Janina Cramer, Tobias Restle, Andreas Marx | Implications of active site constrain... | |
| 2002 | Marinela Perpelescu, Jun'ichi Kobayashi, Miho Furuta, Yasutomo Ito, Shunji Izuta, Masaharu Takemura, Motoshi Suzuki, Shonen Yoshida | Novel phenalenone derivatives from a ... | |
| 2002 | Marie-Pierre Golinelli, Stephen H Hughes | Nontemplated base addition by HIV-1 R... | |
| 2002 | Janice D Pata, Bradford R King, Thomas A Steitz | Assembly, purification and crystalliz... | |
| 2002 | Jason W Rausch, Daniela Lener, Jennifer T Miller, John G Julias, Stephen H Hughes, Stuart F J Le Grice | Altering the RNase H primer grip of h... | |
| 2002 | Patrick K O'Neil, Guoli Sun, Hong Yu, Yacov Ron, Joseph P Dougherty, Bradley D Preston | Mutational analysis of HIV-1 long ter... | |
| 2002 | Jingshan Ren, Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, David I Stuart, David K Stammers | Structure of HIV-2 reverse transcript... | |
| 2002 | Robert L Lobato, Eun-Young Kim, Ronald M Kagan, Thomas C Merigan | Genotypic and phenotypic analysis of ... | |
| 2002 | Adrienne M Woodside, F Peter Guengerich | Misincorporation and stalling at O(6)... | |
| 2002 | R Masciari, L Cosco, M C Diaco, Dora N Della, T Ferraro, T Raimondi, B Ruperti, E Santandrea | HIV-1: a case of RT67 deletion in a m... | |
| 2002 | Yven Van Herrewege, Lieve Penne, Chris Vereecken, Katrien Fransen, Guido van der Groen, Luc Kestens, Jan Balzarini, Guido Vanham | Activity of reverse transcriptase inh... | |
| 2002 | Esther Lobatón, Fátima Rodríguez-Barrios, Federico Gago, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez | Synthesis of 3' '-substituted TSAO de... | |
| 2002 | Stefano Aquaro, Raffaele Caliò, Jan Balzarini, Maria Concetta Bellocchi, Enrico Garaci, CF Perno | Macrophages and HIV infection: therap... | |
| 2002 | Mickael Rigourd, Chantal Ehresmann, Michael A. Parniak, Bernard Ehresmann, Roland Marquet | Primer unblocking and rescue of DNA s... | |
| 2002 | Adrian S Ray, Aravind Basavapathruni, Karen S Anderson | Mechanistic studies to understand the... | |
| 2002 | Joeri Auwerx, Thomas W North, Bradley D Preston, George J Klarmann, Erik De Clercq, Jan Balzarini | Chimeric human immunodeficiency virus... | |
| 2002 | Joke Snoeck, Sonia Van Dooren, Kristel Van Laethem, Inge Derdelinckx, Eric Van Wijngaerden, Erik De Clercq, Anne-Mieke Vandamme | Prevalence and origin of HIV-1 group ... | |
| 2002 | Adrienne M Woodside, F Peter Guengerich | Effect of the O6 substituent on misin... | |
| 2002 | Erik De Clercq | New developments in anti-HIV chemothe... | |
| 2002 | Antonio Mas, Blanca M Vázquez-Alvarez, Esteban Domingo, L Menéndez-Arias | Multidrug-resistant HIV-1 reverse tra... | |
| 2002 | Louis M Mansky | HIV mutagenesis and the evolution of ... | |
| 2002 | Christophe Pannecouque, Wim Pluymers, Bénédicte Van Maele, Victor Tetz, Peter Cherepanov, Erik De Clercq, Myriam Witvrouw, Zeger Debyser | New class of HIV integrase inhibitors... | |
| 2002 | Marie-Pierre Golinelli, Stephen H Hughes | Nontemplated nucleotide addition by H... | |
| 2002 | Dimitrios Motakis, Michael A. Parniak | A tight-binding mode of inhibition is... | |
| 2002 | Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak | Destabilization of the HIV-1 reverse ... | |
| 2002 | Zeger Debyser, Peter Cherepanov, Bénédicte Van Maele, Erik De Clercq, Myriam Witvrouw | In search of authentic inhibitors of ... | |
| 2002 | Phillip P Chamberlain, Jingshan Ren, Charles E Nichols, L Douglas, Johan Lennerstrand, Brendan A Larder, David I Stuart, David K Stammers | Crystal structures of Zidovudine- or ... | |
| 2002 | Giuseppe Campiani, Anna Ramunno, Giovanni Maga, Vito Nacci, Caterina Fattorusso, Bruno Catalanotti, Elena Morelli, Ettore Novellino | Non-nucleoside HIV-1 reverse transcri... | |
| 2002 | Giovanni Maga, Silvio Spadari | Combinations against combinations: as... | |
| 2002 | Yoshiyuki Mizushina, Chikako Murakami, Keisuke Ohta, Hirosato Takikawa, Kenji Mori, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi | Selective inhibition of the activitie... | |
| 2002 | Wim Pluymers, Godwin Pais, Bénédicte Van Maele, Christophe Pannecouque, Valery Fikkert, Terrence R Burke, Erik De Clercq, Myriam Witvrouw, Nouri Neamati, Zeger Debyser | Inhibition of human immunodeficiency ... | |
| 2002 | Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg | The M184V mutation in HIV-1 reverse t... | |
| 2002 | Fabienne Brulé, Roland Marquet, Liwei Rong, Mark A. Wainberg, Bernard P Roques, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann | Structural and functional properties ... | |
| 2002 | Peter R Meyer, Suzanne E Matsuura, Adviye A Tolun, Ingrid Pfeifer, Antero G So, John W Mellors, Walter A Scott | Effects of specific zidovudine resist... | |
| 2002 | Nobuyuki Kasai, Yoshiyuki Mizushina, Fumio Sugawara, Kengo Sakaguchi | Three-dimensional structural model an... | |
| 2002 | Karen S Anderson | Perspectives on the molecular mechani... | RT,Associated condition,All properties |
| 2002 | P Richard Harrigan, Mahboob Salim, David K Stammers, Brian Wynhoven, Zabrina L Brumme, Paula McKenna, Brendan A Larder, S D Kemp | A mutation in the 3' region of the hu... | |
| 2002 | Timothy S Fisher, Vinayaka R Prasad | Substitutions of Phe61 located in the... | RT,Associated condition,All properties |
| 2002 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | The M184V mutation reduces the select... | |
| 2002 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Nucleoside analog resistance caused b... | |
| 2002 | Janina Cramer, Michael Strerath, Andreas Marx, Tobias Restle | Exploring the effects of active site ... | RT,Associated condition,All properties |
| 2002 | Koen K A Van Rompay, Tim B Matthews, Joanne Higgins, Don R Canfield, Ross P Tarara, Mark A. Wainberg, Raymond F Schinazi, Niels C Pedersen, Thomas W North | Virulence and reduced fitness of simi... | |
| 2001 | Stephen H Hughes | Molecular matchmaking: NNRTIs can enh... | |
| 2001 | I A Drachkova, Irina O Petruseva, I V Safronov, A L Zakharenko, G V Shishkin, Olga I Lavrik, Svetlana N Khodyreva | [Reagents for modification of protein... | |
| 2001 | A Martinez, C Gil, A Castro, C Perez, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq | Anti-HIV-1 activity of benzothiadiazi... | |
| 2001 | R Hobi, Ulrich Hübscher, K Neftel, E Alteri, B Poncioni, M R Walker, K Woods-Cook, P Schneider, J K Lazdins | Anti-HIV-1 activity in vitro of cefta... | |
| 2001 | Jennifer T Miller, Bernard Ehresmann, Ulrich Hübscher, Stuart F J Le Grice | A novel interaction of tRNA(Lys,3) wi... | |
| 2001 | Masanori Kameoka, Liwei Rong, Matthias Götte, Chen Liang, Rodney S Russell, Mark A. Wainberg | Role for human immunodeficiency virus... | |
| 2001 | Li Fan, Laurie S Kaguni | Multiple regions of subunit interacti... | |
| 2001 | Jingshan Ren, C Nichols, L Bird, P Chamberlain, Kurt L Weaver, S Short, David I Stuart, David K Stammers | Structural mechanisms of drug resista... | |
| 2001 | Ei-Ichi Kodama, Satoru Kohgo, Kenji Kitano, H Machida, Hiroyuki Gatanaga, S Shigeta, Masao Matsuoka, Hiroshi Ohrui, Hiroyuki Mitsuya | 4'-Ethynyl nucleoside analogs: potent... | |
| 2001 | Erik De Clercq, Dominique Schols | Inhibition of HIV infection by CXCR4 ... | |
| 2001 | Liwei Rong, Chen Liang, M Hsu, Xiaofeng Guo, Bernard P Roques, Mark A. Wainberg | HIV-1 nucleocapsid protein and the se... | |
| 2001 | J L Hammond, D L Koontz, Holly Z Bazmi, J R Beadle, S E Hostetler, G D Kini, Kathy A Aldern, Douglas D Richman, Karl Y Hostetler, John W Mellors | Alkylglycerol prodrugs of phosphonofo... | |
| 2001 | Taurai Tasara, Giovanni Maga, Michael O Hottiger, Ulrich Hübscher | HIV-1 reverse transcriptase and integ... | |
| 2001 | Lisa K Naeger, Michael D Miller | Mechanisms of HIV-1 nucleoside revers... | |
| 2001 | Joseph H Chan, J S Hong, R N Hunter , G F Orr, Jill R Cowan, D B Sherman, S M Sparks, B E Reitter, C Webster Andrews, Richard J Hazen, M St Clair, Lawrence R Boone, Robert G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, R J Ott, Jingshan Ren, A Hopkins, David I Stuart, David K Stammers | 2-Amino-6-arylsulfonylbenzonitriles a... | |
| 2001 | Giovanni Maga, Anna Ramunno, Vito Nacci, Giada A Locatelli, Silvio Spadari, Isabella Fiorini, Fausto Baldanti, Stefania Paolucci, Maurizio Zavattoni, Alberto Bergamini, Bruno Galletti, S Muck, Ulrich Hubscher, Gianluca Giorgi, G Guiso, S Caccia, Giuseppe Campiani | The stereoselective targeting of a sp... | |
| 2001 | Stefan G Sarafianos, Kalyan Das, C Tantillo, Arthur D Clark, Jianping Ding, J M Whitcomb, Paul L Boyer, Stephen H Hughes, Edward Arnold | Crystal structure of HIV-1 reverse tr... | |
| 2001 | Giuseppe Campiani, F Aiello, M Fabbrini, Elena Morelli, Anna Ramunno, S Armaroli, Vito Nacci, A Garofalo, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, L Ventura, B Bongiovanni, M Capozzi, F Bolacchi, Stefano Marini, Massimo Coletta, G Guiso, S Caccia | Quinoxalinylethylpyridylthioureas (QX... | |
| 2001 | Wim Pluymers, Erik De Clercq, Zeger Debyser | HIV-1 integration as a target for ant... | |
| 2001 | M D Driscoll, Marie-Pierre Golinelli, Stephen H Hughes | In vitro analysis of human immunodefi... | |
| 2001 | L Menéndez-Arias, A Abraha, ME Quiñones-Mateu, Antonio Mas, M J Camarasa, E J Arts | Functional characterization of chimer... | |
| 2001 | Jan Balzarini, Erik De Clercq | Rapid alternation of drug therapy is ... | |
| 2001 | Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | RNase H cleavage of the 5' end of the... | |
| 2001 | Matthias Götte, Masanori Kameoka, N McLellan, Luciano Cellai, Mark A. Wainberg | Analysis of efficiency and fidelity o... | |
| 2001 | M Gutiérrez-Rivas, L Menéndez-Arias | A mutation in the primer grip region ... | |
| 2001 | M Lavigne, L Polomack, H Buc | Structures of complexes formed by HIV... | |
| 2001 | Cristina Chamorro, Esther Lobatón, María-Cruz Bonache, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, Ana San-Félix, María-José Camarasa | Identification of a novel family of n... | |
| 2001 | H Pelemans, Robert Esnouf, K L Min, M Parniak, Erik De Clercq, Jan Balzarini | Mutations at amino acid positions 63,... | |
| 2001 | Donald W Ludovici, Robert W Kavash, Michael J Kukla, Chih Y Ho, Hong Ye, B L De Corte, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, H E Moereels, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Paul J Lewi, Kalyan Das, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | K E Squires | An introduction to nucleoside and nuc... | |
| 2001 | Paul L Boyer, Hong Qiang Gao, P Frank, Patrick K Clark, Stephen H Hughes | The basic loop of the RNase H domain ... | |
| 2001 | A L Zakharenko, Dmitry M Kolpashchikov, Svetlana N Khodyreva, Olga I Lavrik, L Menéndez-Arias | Investigation of the dNTP-binding sit... | |
| 2001 | Jan Balzarini, María-José Camarasa, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, CF Perno, Erik De Clercq, J N Anderson, Anna Karlsson | Exploitation of the low fidelity of h... | |
| 2001 | Donald W Ludovici, B L De Corte, Michael J Kukla, Hong Ye, Chih Y Ho, Mark A Lichtenstein, Robert W Kavash, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Kalyan Das, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | J Y Wang, Hong Ling, Wei Wen Yang, R Craigie | Structure of a two-domain fragment of... | |
| 2001 | Johan Lennerstrand, Kurt Hertogs, David K Stammers, Brendan A Larder | Correlation between viral resistance ... | |
| 2001 | Fátima Rodríguez-Barrios, C Pérez, Esther Lobatón, Sonsoles Velázquez, Cristina Chamorro, Ana San-Félix, María-Jesús Pérez-Pérez, María-José Camarasa, H Pelemans, Jan Balzarini, Federico Gago | Identification of a putative binding ... | |
| 2001 | Elena N Peletskaya, Paul L Boyer, Alex A Kogon, Patrick K Clark, Heiko Kroth, Jane M Sayer, Donald M Jerina, Stephen H Hughes | Cross-linking of the fingers subdomai... | |
| 2001 | G Tachedjian, M Orlova, Stefan G Sarafianos, Edward Arnold, S P Goff | Nonnucleoside reverse transcriptase i... | |
| 2001 | H Pelemans, A Aertsen, Kristel Van Laethem, A-M Vandamme, Erik De Clercq, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, María-José Camarasa, Jan Balzarini | Site-directed mutagenesis of human im... | |
| 2001 | G H Kijak, S E Pampuro, M M Avila, C Zala, P Cahn, Mark A. Wainberg, H Salomón | Resistance profiles to antiretroviral... | |
| 2001 | V Molteni, J Greenwald, D Rhodes, Y Hwang, W Kwiatkowski, F D Bushman, J S Siegel, S Choe | Identification of a small-molecule bi... | |
| 2001 | Phillip A Furman, J Jeffrey, L L Kiefer, Joy Y Feng, Karen S Anderson, K Borroto-Esoda, E Hill, William C Copeland, Chung K Chu, J P Sommadossi, I Liberman, Raymond F Schinazi, George R Painter | Mechanism of action of 1-beta-D-2,6-d... | |
| 2001 | Hiroshi Ohrui, Hiroyuki Mitsuya | 4'-C-substituted-2'-deoxynucleosides:... | |
| 2001 | Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Paul L Boyer, Paul Lewi, Paul A J Janssen, Jörg-Peter Kleim, M Rösner, Stephen H Hughes, Edward Arnold | The Lys103Asn mutation of HIV-1 RT: a... | |
| 2001 | M Madrid, J A Lukin, J D Madura, Jianping Ding, Edward Arnold | Molecular dynamics of HIV-1 reverse t... | |
| 2001 | Donald W Ludovici, Michael J Kukla, P G Grous, S Krishnan, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Erik De Clercq, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Selective excision of AZTMP by drug-r... | |
| 2001 | Z Sevilya, S Loya, Stephen H Hughes, A Hizi | The ribonuclease H activity of the re... | |
| 2001 | Alba Chimirri, Pietro Monforte, Angela Rao, Maria Zappalà, Anna-Maria Monforte, G De Sarro, Christophe Pannecouque, Myriam Witvrouw, Jan Balzarini, Erik De Clercq | Synthesis, biological activity, pharm... | |
| 2001 | Erik De Clercq | New developments in anti-HIV chemothe... | |
| 2001 | Paul L Boyer, Hong Qiang Gao, Patrick K Clark, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | YADD mutants of human immunodeficienc... | |
| 2001 | Catherine Isel, Chantal Ehresmann, P Walter, Bernard Ehresmann, Roland Marquet | The emergence of different resistance... | |
| 2001 | J E Fitzgibbon, B DiCola, Edward Arnold, Kalyan Das, B E Sha, J C Pottage, R Nahass, S Gaur, J F John | HIV-1 reverse transcriptase mutations... | |
| 2000 | Nicolas Sluis-Cremer, G I Dmitrienko, Jan Balzarini, María-José Camarasa, Michael A. Parniak | Human immunodeficiency virus type 1 r... | |
| 2000 | Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak | Molecular mechanisms of HIV-1 resista... | |
| 2000 | Kamalendra Singh, Neerja Kaushik, J Jin, M Madhusudanan, Mukund J Modak | Role of Q190 of MuLV RT in ddNTP resi... | |
| 2000 | Matthias Götte, Mark A. Wainberg | Biochemical mechanisms involved in ov... | |
| 2000 | Lawrence A Loeb, J I Mullins | Lethal mutagenesis of HIV by mutageni... | |
| 2000 | Kristel Van Laethem, J C Schmit, H Pelemans, Jan Balzarini, Myriam Witvrouw, María-Jesús Pérez-Pérez, María-José Camarasa, R M Esnouf, Stefano Aquaro, A Cenci, CF Perno, P Hermans, S Sprecher, L Ruiz, B Clotet, Eric Van Wijngaerden, M Van Ranst, J Desmyter, Erik De Clercq, A-M Vandamme | Presence of 2',5'-Bis-O-(tert-butyldi... | |
| 2000 | Paul L Boyer, Stephen H Hughes | Effects of amino acid substitutions a... | |
| 2000 | A J Brown, H M Precious, Jeannette M Whitcomb, J K Wong, M Quigg, Wei Huang, E S Daar, R T D'Aquila, P H Keiser, E Connick, Nicholas S Hellmann, Christos J Petropoulos, Douglas D Richman, S J Little | Reduced susceptibility of human immun... | |
| 2000 | H Salomon, Mark A. Wainberg, Bluma G Brenner, Yudong Quan, D Rouleau, P Coté, R LeBlanc, E Lefebvre, Bonnie Spira, C Tsoukas, Rafick-Pierre Sekaly, Brian Conway, D Mayers, Jean-Pierre Routy | Prevalence of HIV-1 resistant to anti... | |
| 2000 | A Khorchid, H Javanbakht, S Wise, R Halwani, Michael A. Parniak, Mark A. Wainberg, Lawrence Kleiman | Sequences within Pr160gag-pol affecti... | |
| 2000 | Bluma G Brenner, Mark A. Wainberg, H Salomon, D Rouleau, A Dascal, Bonnie Spira, Rafick-Pierre Sekaly, Brian Conway, Jean-Pierre Routy | Resistance to antiretroviral drugs in... | |
| 2000 | N Richard, H Salomon, Maureen Oliveira, R Rando, T Mansour, Z Gu, Mark A. Wainberg | Selection of resistance-conferring mu... | |
| 2000 | L T Bacheler, E D Anton, P Kudish, D Baker, J Bunville, K Krakowski, L Bolling, M Aujay, X V Wang, D Ellis, M F Becker, A L Lasut, H J George, D R Spalding, G Hollis, K Abremski | Human immunodeficiency virus type 1 m... | |
| 2000 | N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of hum... | |
| 2000 | Peter R Meyer, Suzanne E Matsuura, Raymond F Schinazi, Antero G So, Walter A Scott | Differential removal of thymidine nuc... | |
| 2000 | Antonio Mas, M Parera, C Briones, V Soriano, Miguel Angel Martínez, Esteban Domingo, L Menéndez-Arias | Role of a dipeptide insertion between... | |
| 2000 | H Pelemans, Robert Esnouf, Erik De Clercq, Jan Balzarini | Mutational analysis of trp-229 of hum... | |
| 2000 | Jan Balzarini, Erik De Clercq, A Carbonez, V Burt, Jörg-Peter Kleim | Long-term exposure of HIV type 1-infe... | |
| 2000 | Jingshan Ren, J Diprose, J Warren, R M Esnouf, Louise E Bird, Shinji Ikemizu, M Slater, John Milton, Jan Balzarini, David I Stuart, David K Stammers | Phenylethylthiazolylthiourea (PETT) n... | |
| 2000 | Christos J Petropoulos, N T Parkin, K L Limoli, Y S Lie, Terri Wrin, Wei Huang, H Tian, D Smith, G A Winslow, D J Capon, Jeannette M Whitcomb | A novel phenotypic drug susceptibilit... | |
| 2000 | Giuseppe Campiani, M Fabbrini, Elena Morelli, Vito Nacci, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, C Fracasso, S Caccia | Non-nucleoside HIV-1 reverse transcri... | |
| 2000 | Jan Balzarini | Evaluation of Compounds Against Recom... | |
| 2000 | K Nozawa, Motoshi Suzuki, Masaharu Takemura, Shonen Yoshida | In vitro expansion of mammalian telom... | |
| 2000 | Kurt Hertogs, Stuart Bloor, V De Vroey, C van Den Eynde, Pascale Dehertogh, A van Cauwenberge, Martin Stürmer, T Alcorn, S Wegner, M van Houtte, V Miller, Brendan A Larder | A novel human immunodeficiency virus ... | |
| 2000 | P Richard Harrigan, C Stone, P Griffin, I Nájera, Stuart Bloor, S Kemp, M Tisdale, Brendan A Larder | Resistance profile of the human immun... | |
| 2000 | A-M Vandamme, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Kristel Van Laethem, J C Schmit, J Desmyter, Erik De Clercq | Evaluating Clinical Isolates for Thei... | |
| 2000 | Matthias Götte, Dominique Arion, Michael A. Parniak, Mark A. Wainberg | The M184V mutation in the reverse tra... | |
| 2000 | Hong Qiang Gao, Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | The role of steric hindrance in 3TC r... | |
| 2000 | C de Mendoza, V Soriano, C Briones, O Gallego, P Barreiro, A Alvarez, J González-Lahoz | Emergence of zidovudine resistance in... | |
| 2000 | P Bonfanti, I Faggion, S La Seta Catamancio, M Violin, C Balotta, S Rusconi | Response to antiretroviral therapy in... | |
| 2000 | Dominique Arion, Nicolas Sluis-Cremer, Michael A. Parniak | Mechanism by which phosphonoformic ac... | |
| 2000 | F S Shah, Kenneth A Curr, Monica E Hamburgh, M Parniak, Hiroyuki Mitsuya, J G Arnez, Vinayaka R Prasad | Differential influence of nucleoside ... | |
| 2000 | Ming Yu, W Kabat, Jian Wang | [Rapid detection of drug resistant HI... | |
| 2000 | Neerja Kaushik, T T Talele, P K Pandey, D Harris, P N Yadav, V N Pandey | Role of glutamine 151 of human immuno... | |
| 2000 | Nicolas Sluis-Cremer, Dominique Arion, Neerja Kaushik, H Lim, Michael A. Parniak | Mutational analysis of Lys65 of HIV-1... | |
| 2000 | K K Weiss, S J Isaacs, N H Tran, Elinor T Adman, Baek Kim | Molecular architecture of the mutagen... | |
| 2000 | L Mu, Stefan G Sarafianos, Marc C Nicklaus, P Russ, Maqbool A Siddiqui, H Ford, Hiroyuki Mitsuya, R Le, Eiichi N Kodama, Chris Meier, T Knispel, L Anderson, Joseph J Barchi, Victor E Marquez | Interactions of conformationally bias... | |
| 2000 | Jingshan Ren, C Nichols, Louise E Bird, Tsuyoshi Fujiwara, H Sugimoto, David I Stuart, David K Stammers | Binding of the second generation non-... | |
| 2000 | Jingshan Ren, John Milton, Kurt L Weaver, Steven A Short, David I Stuart, David K Stammers | Structural basis for the resilience o... | |
| 2000 | T V Rao, M T Haber, Jane M Sayer, Donald M Jerina | Incorporation of 4-thiothymidine into... | |
| 2000 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Analysis of mutations at positions 11... | |
| 2000 | Mickael Rigourd, J M Lanchy, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann, Roland Marquet | Inhibition of the initiation of HIV-1... | |
| 2000 | W R Davis, J Tomsho, S Nikam, E M Cook, D Somand, J A Peliska | Inhibition of HIV-1 reverse transcrip... | |
| 2000 | T Imamichi, T Sinha, H Imamichi, Y M Zhang, J A Metcalf, J Falloon, H C Lane | High-level resistance to 3'-azido-3'-... | |
| 2000 | Neerja Kaushik, K Chowdhury, V N Pandey, Mukund J Modak | Valine of the YVDD motif of moloney m... | |
| 2000 | Myriam Witvrouw, Valery Fikkert, Wim Pluymers, B Matthews, K Mardel, Dominique Schols, J Raff, Zeger Debyser, Erik De Clercq, G Holan, Christophe Pannecouque | Polyanionic (i.e., polysulfonate) den... | |
| 2000 | D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando | Drug resistance and drug combination ... | |
| 2000 | A Casimiro-Garcia, Erik De Clercq, Christophe Pannecouque, Myriam Witvrouw, T L Stup, J A Turpin, Robert W Buckheit, Mark Cushman | Synthesis and anti-HIV activity of co... | |
| 2000 | Erik De Clercq | Current lead natural products for the... | |
| 2000 | K Van Vaerenbergh, Kristel Van Laethem, J Albert, Charles A B Boucher, B Clotet, M Floridia, J Gerstoft, B Hejdeman, C Nielsen, Christophe Pannecouque, L Perrin, M F Pirillo, L Ruiz, J C Schmit, F Schneider, A Schoolmeester, Rob Schuurman, H J Stellbrink, L Stuyver, J Van Lunzen, Barbara Van Remoortel, Eric Van Wijngaerden, S Vella, Myriam Witvrouw, Sabine Yerly, Erik De Clercq, J Destmyer, Anne-Mieke Vandamme | Prevalence and characteristics of mul... | |
| 2000 | Holly Z Bazmi, J L Hammond, S C Cavalcanti, Chung K Chu, Raymond F Schinazi, John W Mellors | In vitro selection of mutations in th... | |
| 2000 | V Miller, M Ait-Khaled, C Stone, P Griffin, D Mesogiti, A Cutrell, R Harrigan, Schlomo Staszewski, C Katlama, G Pearce, M Tisdale | HIV-1 reverse transcriptase (RT) geno... | |
| 2000 | Myriam Witvrouw, Christophe Pannecouque, J Desmyter, Erik De Clercq, Koen Andries | In vitro evaluation of the effect of ... | |
| 2000 | H Jonckheere, Erik De Clercq, J Anné | Fidelity analysis of HIV-1 reverse tr... | |
| 2000 | H Jonckheere, J Anné, Erik De Clercq | The HIV-1 reverse transcription (RT) ... | |
| 2000 | E P Coakley, J M Gillis, S M Hammer | Phenotypic and genotypic resistance p... | |
| 2000 | C E Cases-Gonzalez, M Gutierrez-Rivas, L Menéndez-Arias | Coupling ribose selection to fidelity... | |
| 2000 | G J Latham, E Forgacs, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd | Vertical-scanning mutagenesis of a cr... | |
| 2000 | S Najmudin, Marie L Coté, D Sun, S Yohannan, Sherwin P Montano, J Gu, Millie M Georgiadis | Crystal structures of an N-terminal f... | |
| 2000 | Michael A. Parniak, Nicolas Sluis-Cremer | Inhibitors of HIV-1 reverse transcrip... | |
| 1999 | Myriam Witvrouw, Christophe Pannecouque, Kristel Van Laethem, J Desmyter, Erik De Clercq, Anne-Mieke Vandamme | Activity of non-nucleoside reverse tr... | |
| 1999 | Giuseppe Campiani, Elena Morelli, M Fabbrini, Vito Nacci, Giovanni Greco, Ettore Novellino, Anna Ramunno, Giovanni Maga, Silvio Spadari, G Caliendo, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, A Nacca, S Caccia | Pyrrolobenzoxazepinone derivatives as... | |
| 1999 | Myriam Witvrouw, Christophe Pannecouque, Erik De Clercq, E Fernández-Alvarez, J L Marco | Inhibition of human immunodeficiency ... | |
| 1999 | J Izopet, A Bicart-See, C Pasquier, K Sandres, E Bonnet, B Marchou, J Puel, P Massip | Mutations conferring resistance to zi... | |
| 1999 | M E Arranz, J A Díaz, S T Ingate, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, S Vega | Synthesis and anti-HIV activity of 1,... | |
| 1999 | Brendan A Larder, Stuart Bloor, S D Kemp, Kurt Hertogs, R L Desmet, V Miller, M Sturmer, Schlomo Staszewski, Jingshan Ren, David K Stammers, David I Stuart, Rudi Pauwels | A family of insertion mutations betwe... | |
| 1999 | Peter R Meyer, Suzanne E Matsuura, A M Mian, Antero G So, Walter A Scott | A mechanism of AZT resistance: an inc... | |
| 1999 | I Pellegrin, J Izopet, J Reynes, M Denayrolles, Brigitte Montes, J L Pellegrin, P Massip, J Puel, H Fleury, Michel Segondy | Emergence of zidovudine and multidrug... | |
| 1999 | A Rakik, M Ait-Khaled, P Griffin, T A Thomas, M Tisdale, Jörg-Peter Kleim | A novel genotype encoding a single am... | |
| 1999 | Joy Y Feng, Karen S Anderson | Mechanistic studies comparing the inc... | |
| 1999 | Neerja Kaushik, Kamalendra Singh, I Alluru, Mukund J Modak | Tyrosine 222, a member of the YXDD mo... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Touching the heart of HIV-1 drug resi... | |
| 1999 | Mark A. Wainberg, Michael D Miller, Yudong Quan, H Salomon, A S Mulato, P D Lamy, Nicolas A Margot, K E Anton, J M Cherrington | In vitro selection and characterizati... | |
| 1999 | J M de Muys, H Gourdeau, N Nguyen-Ba, D L Taylor, P S Ahmed, T Mansour, C Locas, N Richard, Mark A. Wainberg, R F Rando | Anti-human immunodeficiency virus typ... | |
| 1999 | Yudong Quan, Liwei Rong, Chen Liang, Mark A. Wainberg | Reverse transcriptase inhibitors can ... | |
| 1999 | T Szyperski, Matthias Götte, M Billeter, E Perola, Luciano Cellai, H Heumann, K Wüthrich | NMR structure of the chimeric hybrid ... | |
| 1999 | Y Goldgur, R Craigie, G H Cohen, Tsuyoshi Fujiwara, T Yoshinaga, T Fujishita, H Sugimoto, T Endo, H Murai, D R Davies | Structure of the HIV-1 integrase cata... | |
| 1999 | H Rübsamen-Waigmann, E Huguenel, A Shah, A Paessens, H J Ruoff, H von Briesen, A Immelmann, U Dietrich, Mark A. Wainberg | Resistance mutations selected in vivo... | |
| 1999 | N Richar, Yudong Quan, H Salomon, M Hsu, J Bedard, P Richard Harrigan, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of HIV... | |
| 1999 | P F Lin, C J González, B Griffith, G Friedland, V Calvez, F Ferchal, Raymond F Schinazi, D H Shepp, A B Ashraf, Mark A. Wainberg, V Soriano, John W Mellors, R J Colonno | Stavudine resistance: an update on su... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Arthur D Clark, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Lamivudine (3TC) resistance in HIV-1 ... | |
| 1999 | S Cen, Yangxin Huang, A Khorchid, J L Darlix, Mark A. Wainberg, Lawrence Kleiman | The role of Pr55(gag) in the annealin... | |
| 1999 | G Borkow, Dominique Arion, Mark A. Wainberg, Michael A. Parniak | The thiocarboxanilide nonnucleoside i... | |
| 1999 | Paul L Boyer, J Lisziewicz, F Lori, Stephen H Hughes | Analysis of amino insertion mutations... | |
| 1999 | L L Furge, F Peter Guengerich | Explanation of pre-steady-state kinet... | |
| 1999 | Michael D Miller, K E Anton, A S Mulato, P D Lamy, J M Cherrington | Human immunodeficiency virus type 1 e... | |
| 1999 | Lawrence A Loeb, J M Essigmann, F Kazazi, Jun Zhang, K D Rose, J I Mullins | Lethal mutagenesis of HIV with mutage... | |
| 1999 | Matthias Götte, Xincang Li, Mark A. Wainberg | HIV-1 reverse transcription: a brief ... | |
| 1999 | Alexandra Vaisman, Susan E Lim, S M Patrick, William C Copeland, David C Hinkle, J J Turchi, Stephen G Chaney | Effect of DNA polymerases and high mo... | |
| 1999 | Yudong Quan, Dimitrios Motakis, R Buckheit, Z Q Xu, M T Flavin, Michael A. Parniak, Mark A. Wainberg | Sensitivity and resistance to (+)-cal... | |
| 1999 | H Idriss, S Kawa, Z Damuni, E B Thompson, Samuel H Wilson | HIV-1 reverse transcriptase is phosph... | |
| 1999 | Z Gu, Mark A. Wainberg, N Nguyen-Ba, L L'Heureux, J M de Muys, T L Bowlin, R F Rando | Mechanism of action and in vitro acti... | |
| 1999 | Thomas A Steitz | DNA polymerases: structural diversity... | |
| 1999 | Junxing Shi, J J McAtee, S Schlueter Wirtz, P Tharnish, A Juodawlkis, Dennis C Liotta, Raymond F Schinazi | Synthesis and biological evaluation o... | |
| 1999 | Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari | Molecular basis for the enantioselect... | |
| 1999 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, David I Stuart, David K Stammers | Crystallographic analysis of the bind... | |
| 1999 | Andrew L Hopkins, Jingshan Ren, Hiromichi Tanaka, Masanori Baba, M Okamato, David I Stuart, David K Stammers | Design of MKC-442 (emivirine) analogu... | |
| 1999 | M Högberg, Christer Sahlberg, P Engelhardt, Rolf Noréen, J Kangasmetsä, N G Johansson, Bo Oberg, L Vrang, Haijiang Zhang, B L Sahlberg, Torsten Unge, S Lövgren, Kerstin Fridborg, K Bäckbro | Urea-PETT compounds as a new class of... | |
| 1999 | Dominique Arion, Michael A. Parniak | HIV resistance to zidovudine: the rol... | |
| 1999 | Katarzyna Bebenek, J C Boyer, Thomas A Kunkel | The base substitution fidelity of HIV... | |
| 1999 | M Wisniewski, C Palaniappan, Z Fu, Stuart F J Le Grice, P Fay, Robert A Bambara | Mutations in the primer grip region o... | |
| 1999 | M D Powell, William A Beard, Katarzyna Bebenek, K J Howard, Stuart F J Le Grice, Thomas A Darden, Thomas A Kunkel, Samuel H Wilson, J G Levin | Residues in the alphaH and alphaI hel... | |
| 1999 | D A Lewis, Katarzyna Bebenek, William A Beard, Samuel H Wilson, Thomas A Kunkel | Uniquely altered DNA replication fide... | |
| 1999 | Baek Kim, J C Ayran, S G Sagar, Elinor T Adman, S M Fuller, N H Tran, J Horrigan | New human immunodeficiency virus, typ... | |
| 1999 | Zucai Suo, S J Lippard, Kenneth A Johnson | Single d(GpG)/cis-diammineplatinum(II... | |
| 1999 | Matthias Götte, G Maier, A M Onori, Luciano Cellai, Mark A. Wainberg, H Heumann | Temporal coordination between initiat... | |
| 1999 | Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Similarities and differences in the R... | |
| 1999 | Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | Action of a new mammalian DNA polymer... | |
| 1999 | Sylvie Doublié, M R Sawaya, Tom Ellenberger | An open and closed case for all polym... | |
| 1999 | Taurai Tasara, Mario Amacker, Ulrich Hübscher | Intramolecular chimeras of the p51 su... | |
| 1999 | J J de Jong, J Goudsmit, V V Lukashov, M E Hillebrand, E Baan, R Huismans, Sven A Danner, J H ten Veen, F de Wolf, Suzanne Jurriaans | Insertion of two amino acids combined... | |
| 1999 | Jan Balzarini | Suppression of resistance to drugs ta... | |
| 1999 | Sonsoles Velázquez, V Tuñón, M L Jimeno, Cristina Chamorro, Erik De Clercq, Jan Balzarini, María-José Camarasa | Potential multifunctional inhibitors ... | |
| 1999 | Andreas Marx, M Spichty, Mario Amacker, U Schwitter, Ulrich Hübscher, Thomas A Bickle, Giovanni Maga, Bernd Giese | Probing interactions between HIV-1 re... | |
| 1999 | M Madrid, A Jacobo-Molina, Jianping Ding, Edward Arnold | Major subdomain rearrangement in HIV-... | |
| 1998 | Zucai Suo, Kenneth A Johnson | DNA secondary structure effects on DN... | |
| 1998 | A Acel, B E Udashkin, Mark A. Wainberg, E A Faust | Efficient gap repair catalyzed in vit... | |
| 1998 | F J Palella, K M Delaney, A C Moorman, M O Loveless, J Fuhrer, G A Satten, D J Aschman, S D Holmberg | Declining morbidity and mortality amo... | |
| 1998 | C Tamalet, J Izopet, N Koch, J Fantini, N Yahi | Stable rearrangements of the beta3-be... | |
| 1998 | C Katlama, M A Valantin, S Matheron, A Coutellier, V Calvez, D Descamps, C Longuet, M Bonmarchand, R Tubiana, M De Sa, R Lancar, Henri Agut, F Brun-Vezinet, D Costagliola | Efficacy and tolerability of stavudin... | |
| 1998 | Akitsu Ogawa, Takashi Murate, Shunji Izuta, Masaharu Takemura, Kyoji Furuta, Jun'ichi Kobayashi, T Kamikawa, Y Nimura, Shonen Yoshida | Sulfated glycoglycerolipid from archa... | |
| 1998 | Zucai Suo, Kenneth A Johnson | Selective inhibition of HIV-1 reverse... | |
| 1998 | Monica E Hamburgh, William C Drosopoulos, Vinayaka R Prasad | The influence of 3TC-resistance mutat... | |
| 1998 | Jianping Ding, Kalyan Das, Y Hsiou, Stefan G Sarafianos, Arthur D Clark, A Jacobo-Molina, C Tantillo, Stephen H Hughes, Edward Arnold | Structure and functional implications... | |
| 1998 | Hao Huang, R Chopra, G L Verdine, S C Harrison | Structure of a covalently trapped cat... | |
| 1998 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, J Warren, Jan Balzarini, David I Stuart, David K Stammers | Crystal structures of HIV-1 reverse t... | |
| 1998 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, E Yvonne Jones, I Kirby, J Keeling, C K Ross, Brendan A Larder, David I Stuart, David K Stammers | 3'-Azido-3'-deoxythymidine drug resis... | |
| 1998 | Joachim Jaeger, Tobias Restle, Thomas A Steitz | The structure of HIV-1 reverse transc... | |
| 1998 | Y Hsiou, Kalyan Das, Jianping Ding, Arthur D Clark, Jörg-Peter Kleim, M Rösner, I Winkler, G Riess, Stephen H Hughes, Edward Arnold | Structures of Tyr188Leu mutant and wi... | |
| 1998 | S W Graves, Allison A Johnson, Kenneth A Johnson | Expression, purification, and initial... | Processivity,Kd,Vmax,All properties |
| 1998 | Baek Kim, T R Hathaway, Lawrence A Loeb | Fidelity of mutant HIV-1 reverse tran... | |
| 1998 | D Harris, P N Yadav, V N Pandey | Loss of polymerase activity due to Ty... | |
| 1998 | D Harris, Neerja Kaushik, P K Pandey, P N Yadav, V N Pandey | Functional analysis of amino acid res... | |
| 1998 | Matthias Götte, G Maier, H J Gross, H Heumann | Localization of the active site of HI... | |
| 1998 | G Tachedjian, John W Mellors, H Bazmi, J Mills | Impaired fitness of foscarnet-resista... | |
| 1998 | Dominique Arion, Neerja Kaushik, Suzanne McCormick, G Borkow, Michael A. Parniak | Phenotypic mechanism of HIV-1 resista... | |
| 1998 | Bruno Canard, S R Sarfati, Charles C Richardson | Enhanced binding of azidothymidine-re... | |
| 1998 | Peter R Meyer, Suzanne E Matsuura, Antero G So, Walter A Scott | Unblocking of chain-terminated primer... | |
| 1998 | Joseph A Vaccaro, Karen S Anderson | Implication of the tRNA initiation st... | |
| 1998 | M A Winters, K L Coolley, Y A Girard, D J Levee, H Hamdan, R W Shafer, D A Katzenstein, T C Merigan | A 6-basepair insert in the reverse tr... | |
| 1998 | Michael D Miller, P D Lamy, M D Fuller, A S Mulato, Nicolas A Margot, T Cihlar, J M Cherrington | Human immunodeficiency virus type 1 r... | |
| 1998 | Mark Cushman, A Casimiro-Garcia, E Hejchman, J A Ruell, M Huang, C A Schaeffer, K Williamson, W G Rice, Robert W Buckheit | New alkenyldiarylmethanes with enhanc... | |
| 1998 | L M Demeter, P M Meehan, G Morse, M A Fischl, M Para, W Powderly, J Leedom, J Holden-Wiltse, C Greisberger, K Wood, J Timpone, L K Wathen, T Nevin, L Resnick, D H Batts, R C Reichman | Phase I study of atevirdine mesylate ... | |
| 1998 | Tsuyoshi Fujiwara, Akira Sato, M el-Farrash, S Miki, K Abe, Y Isaka, M Kodama, Y Wu, L B Chen, H Harada, H Sugimoto, Masami Hatanaka, Y Hinuma | S-1153 inhibits replication of known ... | |
| 1998 | Myriam Witvrouw, M E Arranz, Christophe Pannecouque, R Declercq, H Jonckheere, J C Schmit, A-M Vandamme, J A Diaz, S T Ingate, J Desmyter, Robert Esnouf, L Van Meervelt, S Vega, Jan Balzarini, Erik De Clercq | 1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,... | |
| 1998 | H Pelemans, R M Esnouf, Michael A. Parniak, A-M Vandamme, Erik De Clercq, Jan Balzarini | A proline-to-histidine substitution a... | |
| 1998 | H Togashi, Yoshiyuki Mizushina, Masaharu Takemura, Fumio Sugawara, Hiroyuki Koshino, Y Esumi, J Uzawa, H Kumagai, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | 4-Hydroxy-17-methylincisterol, an inh... | |
| 1998 | Yoshiyuki Mizushina, L Hanashima, Tsuyoshi Yamaguchi, Masaharu Takemura, Fumio Sugawara, Mineo Saneyoshi, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | A mushroom fruiting body-inducing sub... | |
| 1998 | Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | Sulfoquinovosyldiacylglycerol, KM043,... | |
| 1998 | M Nakayabu, S Miwa, Motoshi Suzuki, Shunji Izuta, G Sobue, Shonen Yoshida | Mismatched nucleotides may facilitate... | |
| 1998 | H J Einolf, N Schnetz-Boutaud, F Peter Guengerich | Steady-state and pre-steady-state kin... | |
| 1998 | Silvio Spadari, Giovanni Maga, A Verri, Federico Focher | Molecular basis for the antiviral and... | |
| 1998 | William A Beard, Katarzyna Bebenek, Thomas A Darden, Lin Li, Rajendra Prasad, Thomas A Kunkel, Samuel H Wilson | Vertical-scanning mutagenesis of a cr... | |
| 1998 | I Choudhury, Jianhong Wang, A B Rabson, S Stein, S Pooyan, S Stein, M J Leibowitz | Inhibition of HIV-1 replication by a ... | |
| 1998 | Andreas Marx, Mario Amacker, M Stucki, Ulrich Hübscher, Thomas A Bickle, Bernd Giese | 4'-Acylated thymidine 5'-triphosphate... | |
| 1998 | M von Janta-Lipinski, B Costisella, H Ochs, Ulrich Hübscher, P Hafkemeyer, E Matthes | Newly synthesized L-enantiomers of 3'... | |
| 1998 | Mario Amacker, Ulrich Hübscher | Chimeric HIV-1 and feline immunodefic... | |
| 1998 | Hong Qiang Gao, Paul L Boyer, Edward Arnold, Stephen H Hughes | Effects of mutations in the polymeras... | |
| 1998 | D V Nissley, Paul L Boyer, D J Garfinkel, Stephen H Hughes, J N Strathern | Hybrid Ty1/HIV-1 elements used to det... | |
| 1998 | Paul L Boyer, Hong Qiang Gao, Stephen H Hughes | A mutation at position 190 of human i... | |
| 1998 | Yudong Quan, P Inouye, Chen Liang, Liwei Rong, Matthias Götte, Mark A. Wainberg | Dominance of the E89G substitution in... | |
| 1998 | H Salomon, Julio S G Montaner, A Belmonte, Mark A. Wainberg | Diminished HIV-1 sensitivity to stavu... | |
| 1998 | Yudong Quan, Chen Liang, P Inouye, Mark A. Wainberg | Enhanced impairment of chain elongati... | |
| 1998 | E Cherry, Chen Liang, Liwei Rong, Yudong Quan, P Inouye, Xincang Li, N Morin, M Kotler, Mark A. Wainberg | Characterization of human immunodefic... | |
| 1998 | William C Drosopoulos, Lisa F Rezende, Mark A. Wainberg, Vinayaka R Prasad | Virtues of being faithful: can we lim... | |
| 1998 | E Cherry, N Morin, Mark A. Wainberg | Effect of HIV constructs containing p... | |
| 1998 | P Inouye, E Cherry, M Hsu, S Zolla-Pazner, Mark A. Wainberg | Neutralizing antibodies directed agai... | |
| 1998 | Yudong Quan, Z Gu, Xincang Li, Chen Liang, Michael A. Parniak, Mark A. Wainberg | Endogenous reverse transcriptase assa... | |
| 1998 | H Kwon, N Pelletier, C DeLuca, P Genin, S Cisternas, R Lin, Mark A. Wainberg, J Hiscott | Inducible expression of IkappaBalpha ... | |
| 1998 | M Wasner, Dominique Arion, G Borkow, A Noronha, A H Uddin, Michael A. Parniak, Masad J Damha | Physicochemical and biochemical prope... | |
| 1998 | Cristina Chamorro, María-José Camarasa, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, Ana San Félix | An approach towards the synthesis of ... | |
| 1998 | Sonsoles Velázquez, Cristina Chamorro, María-Jesús Pérez-Pérez, R Alvarez, M L Jimeno, A Martín-Domenech, C Pérez, Federico Gago, Erik De Clercq, Jan Balzarini, Ana San-Félix, María-José Camarasa | Abasic analogues of TSAO-T as the fir... | |
| 1998 | Erik De Clercq | The role of non-nucleoside reverse tr... | |
| 1998 | J C Schmit, L Ruiz, L Stuyver, Kristel Van Laethem, I Vanderlinden, T Puig, R Rossau, J Desmyter, Erik De Clercq, B Clotet, A-M Vandamme | Comparison of the LiPA HIV-1 RT test,... | |
| 1998 | Erik De Clercq | New perspectives for the treatment of... | |
| 1998 | H Jonckheere, Myriam Witvrouw, Erik De Clercq, J Anné | Lamivudine resistance of HIV type 1 d... | |
| 1998 | Kamalendra Singh, Mukund J Modak | A unified DNA- and dNTP-binding mode ... | |
| 1997 | S Loya, Hong Qiang Gao, O Avidan, Paul L Boyer, Stephen H Hughes, A Hizi | Subunit-specific mutagenesis of the c... | |
| 1997 | Robert W Buckheit, M J Snow, V Fliakas-Boltz, T L Kinjerski, J D Russell, L A Pallansch, W G Brouwer, S S Yang | Highly potent oxathiin carboxanilide ... | |
| 1997 | Myriam Witvrouw, Erik De Clercq | Sulfated polysaccharides extracted fr... | |
| 1997 | Jianping Ding, Stephen H Hughes, Edward Arnold | Protein-nucleic acid interactions and... | |
| 1997 | H Pelemans, Robert Esnouf, A Dunkler, Michael A. Parniak, A-M Vandamme, Anna Karlsson, Erik De Clercq, Jörg-Peter Kleim, Jan Balzarini | Characteristics of the Pro225His muta... | |
| 1997 | E Forgacs, G Latham, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd | Probing structure/function relationsh... | |
| 1997 | Jörg-Peter Kleim, I Winkler, M Rösner, R Kirsch, H Rübsamen-Waigmann, A Paessens, G Riess | In vitro selection for different muta... | |
| 1997 | M Tanaka, R V Srinivas, Takayuki Ueno, M F Kavlick, F K Hui, A Fridland, J S Driscoll, Hiroyuki Mitsuya | In vitro induction of human immunodef... | |
| 1997 | Myriam Witvrouw, Jan Balzarini, Christophe Pannecouque, S Jhaumeer-Laulloo, J A Esté, Dominique Schols, Peter Cherepanov, J C Schmit, Zeger Debyser, A-M Vandamme, J Desmyter, S R Ramadas, Erik De Clercq | SRR-SB3, a disulfide-containing macro... | |
| 1997 | Stefano Aquaro, CF Perno, Emanuela Balestra, Jan Balzarini, A Cenci, M Francesconi, S Panti, F Serra, N Villani, Raffaele Caliò | Inhibition of replication of HIV in p... | |
| 1997 | Erik De Clercq | Development of resistance of human im... | |
| 1997 | Yoshiyuki Mizushina, Shonen Yoshida, Akio Matsukage, Kengo Sakaguchi | The inhibitory action of fatty acids ... | |
| 1997 | Jan Balzarini, H Pelemans, G Riess, M Roesner, I Winkler, Erik De Clercq, Jörg-Peter Kleim | Zidovudine-resistant human immunodefi... | |
| 1997 | L L Furge, F Peter Guengerich | Analysis of nucleotide insertion and ... | |
| 1997 | Giovanni Maga, Mario Amacker, N Ruel, Ulrich Hübscher, Silvio Spadari | Resistance to nevirapine of HIV-1 rev... | |
| 1997 | Erik De Clercq | In search of a selective antiviral ch... | |
| 1997 | H Hara, T Fujihashi, T Sakata, A Kaji, H Kaji | Tetrahydronaphthalene lignan compound... | |
| 1997 | I V Safronov, N V Shcherbik, Svetlana N Khodyreva, V A Vlasov, M I Dobrikov, G V Shishkin, Olga I Lavrik | [New photoreactive N(4)-substituted d... | |
| 1997 | B P Burnett, Charles S McHenry | Posttranscriptional modification of r... | |
| 1997 | Bruno Canard, R Sarfati, Charles C Richardson | Binding of RNA template to a complex ... | |
| 1997 | W Keulen, N K Back, A van Wijk, Charles A B Boucher, Ben Berkhout | Initial appearance of the 184Ile vari... | |
| 1997 | Ashwini S Kamath-Loeb, A Hizi, Hironori Kasai, Lawrence A Loeb | Incorporation of the guanosine tripho... | |
| 1997 | G Borkow, Dominique Arion, A Noronha, M Scartozzi, Masad J Damha, Michael A. Parniak | Inhibitory potency of R-region specif... | |
| 1997 | M Hsu, P Inouye, L Rezende, N Richard, Zhongjie Li, Vinayaka R Prasad, Mark A. Wainberg | Higher fidelity of RNA-dependent DNA ... | |
| 1997 | Chen Liang, Liwei Rong, N Morin, E Cherry, Yangxin Huang, Lawrence Kleiman, Mark A. Wainberg | The roles of the human immunodeficien... | |
| 1997 | F Lori, A G Malykh, A Foli, R Maserati, A De Antoni, L Minoli, D Padrini, A Degli Antoni, E Barchi, H Jessen, Mark A. Wainberg, R C Gallo, J Lisziewicz | Combination of a drug targeting the c... | |
| 1997 | Chen Liang, Xincang Li, Liwei Rong, P Inouye, Yudong Quan, Lawrence Kleiman, Mark A. Wainberg | The importance of the A-rich loop in ... | |
| 1997 | Mark A. Wainberg | Increased fidelity of drug-selected M... | |
| 1997 | J Mak, A Khorchid, Q Cao, Yangxin Huang, I Lowy, Michael A. Parniak, Vinayaka R Prasad, Mark A. Wainberg, Lawrence Kleiman | Effects of mutations in Pr160gag-pol ... | |
| 1997 | M D Powell, M Ghosh, P S Jacques, K J Howard, Stuart F J Le Grice, J G Levin | Alanine-scanning mutations in the "pr... | |
| 1997 | C Palaniappan, M Wisniewski, P S Jacques, Stuart F J Le Grice, P J Fay, Robert A Bambara | Mutations within the primer grip regi... | |
| 1997 | Neerja Kaushik, D Harris, N Rege, Mukund J Modak, P N Yadav, V N Pandey | Role of glutamine-151 of human immuno... | |
| 1997 | G Gao, M Orlova, Millie M Georgiadis, W A Hendrickson, S P Goff | Conferring RNA polymerase activity to... | |
| 1997 | A De Antoni, A Foli, J Lisziewicz, F Lori | Mutations in the pol gene of human im... | |
| 1997 | Jan Balzarini, Erik De Clercq, K Uberla | SIV/HIV-1 hybrid virus expressing the... | |
| 1997 | R M Esnouf, David I Stuart, Erik De Clercq, E Schwartz, Jan Balzarini | Models which explain the inhibition o... | |
| 1997 | J Barnard, G Borkow, Michael A. Parniak | The thiocarboxanilide nonnucleoside U... | |
| 1997 | M Tisdale, T Alnadaf, D Cousens | Combination of mutations in human imm... | |
| 1997 | Takayuki Ueno, Hiroyuki Mitsuya | Comparative enzymatic study of HIV-1 ... | |
| 1997 | Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, Koen Andries, Robert W Buckheit, Richard H Smith | Molecular modeling of HIV-1 reverse t... | |
| 1997 | Y M Lin, H Anderson, M T Flavin, Y H Pai, E Mata-Greenwood, T Pengsuparp, J M Pezzuto, Raymond F Schinazi, Stephen H Hughes, F C Chen | In vitro anti-HIV activity of biflavo... | |
| 1997 | A Hizi, Ashwini S Kamath-Loeb, K D Rose, Lawrence A Loeb | Mutagenesis by human immunodeficiency... | |
| 1997 | T Rubinek, M Bakhanashvili, R Taube, O Avidan, A Hizi | The fidelity of 3' misinsertion and m... | |
| 1997 | G Borkow, Ronald S Fletcher, J Barnard, Dominique Arion, Dimitrios Motakis, G I Dmitrienko, Michael A. Parniak | Inhibition of the ribonuclease H and ... | |
| 1997 | G Borkow, J Barnard, T M Nguyen, A Belmonte, Mark A. Wainberg, Michael A. Parniak | Chemical barriers to human immunodefi... | |
| 1997 | S G Kerr, Karen S Anderson | Pre-steady-state kinetic characteriza... | |
| 1997 | R Krebs, U Immendörfer, S H Thrall, B M Wöhrl, R S Goody | Single-step kinetics of HIV-1 reverse... | |
| 1997 | R M Esnouf, Jingshan Ren, Andrew L Hopkins, C K Ross, E Yvonne Jones, David K Stammers, David I Stuart | Unique features in the structure of t... | |
| 1997 | W Tong, C D Lu, S K Sharma, S Matsuura, Antero G So, Walter A Scott | Nucleotide-induced stable complex for... | |
| 1997 | Zucai Suo, Kenneth A Johnson | Effect of RNA secondary structure on ... | |
| 1997 | Zucai Suo, Kenneth A Johnson | RNA secondary structure switching dur... | |
| 1997 | M A Winters, R W Shafer, R A Jellinger, G Mamtora, T Gingeras, T C Merigan | Human immunodeficiency virus type 1 r... | |
| 1997 | Mario Amacker, M Hottiger, R Mossi, Ulrich Hübscher | HIV-1 nucleocapsid protein and replic... | |
| 1997 | Thomas Roth, Marshall L Morningstar, Paul L Boyer, Stephen H Hughes, Robert W Buckheit, Christopher J Michejda | Synthesis and biological activity of ... | |
| 1997 | Zucai Suo, Kenneth A Johnson | Effect of RNA secondary structure on ... | |
| 1996 | T Pengsuparp, M Serit, Stephen H Hughes, D D Soejarto, J M Pezzuto | Specific inhibition of human immunode... | |
| 1996 | M Hottiger, Ulrich Hübscher | Human Immunodeficiency Virus type 1 r... | |
| 1996 | F Soler, C Poujade, M Evers, J C Carry, Y Hénin, Anne Bousseau, T Huet, Rudi Pauwels, Erik De Clercq, J F Mayaux, J B Le Pecq, N Dereu | Betulinic acid derivatives: a new cla... | |
| 1996 | Erik De Clercq | Chemotherapy of human immunodeficienc... | |
| 1996 | Mark A. Wainberg, M Hsu, Z Gu, G Borkow, Michael A. Parniak | Effectiveness of 3TC in HIV clinical ... | |
| 1996 | Zhongjie Li, A Shalom, Yangxin Huang, J Mak, E Arts, Mark A. Wainberg, Lawrence Kleiman | Multiple forms of tRNA(Lys3) in HIV-1. | |
| 1996 | Dominique Arion, R Harada, Xincang Li, Mark A. Wainberg, Michael A. Parniak | HIV-1 reverse transcriptase shows no ... | |
| 1996 | Xincang Li, Yudong Quan, E.J. Arts, Zhongjie Li, Bradley D Preston, H de Rocquigny, Bernard P Roques, J L Darlix, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg | Human immunodeficiency virus Type 1 n... | |
| 1996 | A M Martín-Hernández, Esteban Domingo, L Menéndez-Arias | Human immunodeficiency virus type 1 r... | |
| 1996 | J M Cherrington, M D Fuller, A S Mulato, S J Allen, S C Kunder, M A Ussery, Z Lesnikowski, Raymond F Schinazi, J P Sommadossi, M S Chen | Comparative kinetic analyses of inter... | |
| 1996 | D L Winslow, S Garber, C Reid, H Scarnati, D Baker, M M Rayner, E D Anton | Selection conditions affect the evolu... | |
| 1996 | Jan Balzarini, W G Brouwer, D C Dao, E M Osika, Erik De Clercq | Identification of novel thiocarboxani... | |
| 1996 | Mark A. Wainberg, L Lewis, H Salomon, Z Gu, A Keller, Nick Cammack, J Goldsmith, J Church, Bonnie Spira, S Wheeler, P Pizzo | Resistance to (-)-2',3'-dideoxy-3'-th... | |
| 1996 | Z Gu, Xincang Li, Yudong Quan, Michael A. Parniak, Mark A. Wainberg | Studies of neutralizing monoclonal an... | |
| 1996 | J A Esté, K De Vreese, Myriam Witvrouw, J C Schmit, A-M Vandamme, J Anné, J Desmyter, G W Henson, G Bridger, Erik De Clercq | Antiviral activity of the bicyclam de... | |
| 1996 | Dominique Arion, Ronald S Fletcher, G Borkow, María-José Camarasa, Jan Balzarini, G I Dmitrienko, Michael A. Parniak | Differences in the inhibition of huma... | |
| 1996 | Neerja Kaushik, N Rege, P N Yadav, Stefan G Sarafianos, Mukund J Modak, V N Pandey | Biochemical analysis of catalytically... | |
| 1996 | Mark A. Wainberg, William C Drosopoulos, H Salomon, M Hsu, G Borkow, M Parniak, Z Gu, Q Song, J Manne, S Islam, G Castriota, Vinayaka R Prasad | Enhanced fidelity of 3TC-selected mut... | |
| 1996 | H Jonckheere, K De Vreese, Zeger Debyser, J Vandekerckhove, Jan Balzarini, J Desmyter, Erik De Clercq, J Anné | A two plasmid co-expression system in... | |
| 1996 | William A Beard, Dana T Minnick, C L Wade, Rajendra Prasad, R L Won, A Kumar, Thomas A Kunkel, Samuel H Wilson | Role of the "helix clamp" in HIV-1 re... | |
| 1996 | S Ingate, Erik De Clercq, Jan Balzarini, María-José Camarasa | Novel L-lyxo and 5'-deoxy-5'-modified... | |
| 1996 | Ronald S Fletcher, G Holleschak, Eva Nagy, Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak | Single-step purification of recombina... | |
| 1996 | E.J. Arts, J P Marois, Z Gu, Stuart F J Le Grice, Mark A. Wainberg | Effects of 3'-deoxynucleoside 5'-trip... | |
| 1996 | Jan Balzarini, O Wedgwood, J Kruining, H Pelemans, R Heijtink, Erik De Clercq, Christopher McGuigan | Anti-HIV and anti-HBV activity and re... | |
| 1996 | Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak | The K65R mutation confers increased D... | RT,Cloned or native,Full length or truncated,Extension from RNA primer,All properties |
| 1996 | M G Davis, J E Wilson, N A VanDraanen, W H Miller, George A Freeman, S M Daluge, F L Boyd, A E Aulabaugh, George R Painter, Lawrence R Boone | DNA polymerase activity of hepatitis ... | |
| 1996 | B M Moore, Ke Li, Michael B Doughty | Deoxyadenosine-based DNA polymerase p... | |
| 1996 | D Bellarosa, G Antonelli, F Bambacioni, D Giannotti, G Viti, R Nannicini, A Giachetti, F Dianzani, Myriam Witvrouw, Rudi Pauwels, J Desmyter, Erik De Clercq | New arylpyrido-diazepine and -thiodia... | |
| 1996 | L Hong, A Treharne, J A Hartsuck, S Foundling, J Tang | Crystal structures of complexes of a ... | |
| 1996 | Jan Balzarini, H Pelemans, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson | Marked inhibitory activity of non-nuc... | |
| 1996 | R A Spence, Karen S Anderson, Kenneth A Johnson | HIV-1 reverse transcriptase resistanc... | |
| 1996 | Edward Arnold, Kalyan Das, Jianping Ding, P N Yadav, Y Hsiou, Paul L Boyer, Stephen H Hughes | Targeting HIV reverse transcriptase f... | |
| 1996 | J E Wilson, A Aulabaugh, B Caligan, S McPherson, J K Wakefield, S Jablonski, C D Morrow, J E Reardon, Phillip A Furman | Human immunodeficiency virus type-1 r... | |
| 1996 | Baek Kim, T R Hathaway, Lawrence A Loeb | Human immunodeficiency virus reverse ... | |
| 1996 | J Ji, N J Clegg, K R Peterson, A L Jackson, C D Laird, Lawrence A Loeb | In vitro expansion of GGC:GCC repeats... | |
| 1996 | Zeger Debyser, Erik De Clercq | Chemical crosslinking of the subunits... | |
| 1996 | CF Perno, Emanuela Balestra, Stefano Aquaro, S Panti, A Cenci, G Lazzarino, B Tavazzi, D Di Pierro, Jan Balzarini, R Calio | Potent inhibition of human immunodefi... | |
| 1996 | Rudi Pauwels, Erik De Clercq | Development of vaginal microbicides f... | |
| 1996 | D J Hooker, G Tachedjian, A E Solomon, A D Gurusinghe, S Land, C Birch, J L Anderson, B M Roy, Edward Arnold, N J Deacon | An in vivo mutation from leucine to t... | |
| 1996 | Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Stephen H Hughes, Edward Arnold | Structure of unliganded HIV-1 reverse... | |
| 1996 | Andrew L Hopkins, Jingshan Ren, R M Esnouf, B E Willcox, E Yvonne Jones, C Ross, T Miyasaka, R T Walker, Hiromichi Tanaka, David K Stammers, David I Stuart | Complexes of HIV-1 reverse transcript... | |
| 1996 | R A Olmsted, D E Slade, L A Kopta, S M Poppe, T J Poel, S W Newport, K B Rank, C Biles, R A Morge, T J Dueweke, Y Yagi, D L Romero, R C Thomas, S K Sharma, W G Tarpley | (Alkylamino) piperidine bis(heteroary... | |
| 1996 | G Yang, Q Song, M Charles, William C Drosopoulos, Edward Arnold, Vinayaka R Prasad | Use of chimeric human immunodeficienc... | |
| 1996 | J M Cherrington, A S Mulato, M D Fuller, M S Chen | Novel mutation (K70E) in human immuno... | |
| 1996 | H D Sun, S X Qiu, L Z Lin, Z Y Wang, Z W Lin, T Pengsuparp, J M Pezzuto, H H Fong, G A Cordell, N R Farnsworth | Nigranoic acid, a triterpenoid from S... | |
| 1996 | M Evers, C Poujade, F Soler, Y Ribeill, C James, Y Lelièvre, J C Gueguen, D Reisdorf, I Morize, Rudi Pauwels, Erik De Clercq, Y Hénin, Anne Bousseau, J F Mayaux, J B Le Pecq, N Dereu | Betulinic acid derivatives: a new cla... | |
| 1996 | P Richard Harrigan, I Kinghorn, Stuart Bloor, S D Kemp, I Nájera, A Kohli, Brendan A Larder | Significance of amino acid variation ... | |
| 1996 | A K Iversen, R W Shafer, K Wehrly, M A Winters, J I Mullins, B Chesebro, T C Merigan | Multidrug-resistant human immunodefic... | |
| 1996 | Yudong Quan, Z Gu, Xincang Li, Zhongjie Li, C D Morrow, Mark A. Wainberg | Endogenous reverse transcription assa... | |
| 1996 | V N Pandey, Neerja Kaushik, N Rege, Stefan G Sarafianos, P N Yadav, Mukund J Modak | Role of methionine 184 of human immun... | |
| 1996 | Jörg-Peter Kleim, M Rösner, I Winkler, A Paessens, R Kirsch, Y Hsiou, Edward Arnold, G Riess | Selective pressure of a quinoxaline n... | |
| 1996 | Olga I Lavrik, Rajendra Prasad, William A Beard, I V Safronov, M I Dobrikov, Deepak K Srivastava, G V Shishkin, T G Wood, Samuel H Wilson | dNTP binding to HIV-1 reverse transcr... | |
| 1996 | Kalyan Das, Jianping Ding, Y Hsiou, Arthur D Clark, H Moereels, Luc Koymans, Koen Andries, Rudi Pauwels, Paul A J Janssen, Paul L Boyer, Patrick K Clark, Richard H Smith, Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Edward Arnold | Crystal structures of 8-Cl and 9-Cl T... | |
| 1996 | G Tachedjian, J Mellors, H Bazmi, C Birch, J Mills | Zidovudine resistance is suppressed b... | |
| 1996 | William C Drosopoulos, Vinayaka R Prasad | Increased polymerase fidelity of E89G... | |
| 1996 | Yangxin Huang, A Shalom, Zhongjie Li, Jiong Wang, J Mak, Mark A. Wainberg, Lawrence Kleiman | Effects of modifying the tRNA(3Lys) a... | |
| 1996 | A Foli, K M Sogocio, B Anderson, M Kavlick, M W Saville, Mark A. Wainberg, Z Gu, J M Cherrington, Hiroyuki Mitsuya, R Yarchoan | In vitro selection and molecular char... | |
| 1996 | Stefan G Sarafianos, U Kortz, M T Pope, Mukund J Modak | Mechanism of polyoxometalate-mediated... | |
| 1996 | Charles A B Boucher, W Keulen, T van Bommel, Monique Nijhuis, D de Jong, M D de Jong, P Schipper, N K Back | Human immunodeficiency virus type 1 d... | |
| 1996 | Michael J Lutz, H A Held, M Hottiger, Ulrich Hübscher, Steven A Benner | Differential discrimination of DNA po... | |
| 1996 | L M Mansky | Forward mutation rate of human immuno... | |
| 1996 | N K Back, Monique Nijhuis, W Keulen, Charles A B Boucher, B O Oude Essink, A B van Kuilenburg, A H van Gennip, Ben Berkhout | Reduced replication of 3TC-resistant ... | |
| 1995 | Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak | Glutamine 151 participates in the sub... | |
| 1995 | D W Rodgers, S J Gamblin, B A Harris, S Ray, J S Culp, B Hellmig, D J Woolf, C Debouck, S C Harrison | The structure of unliganded reverse t... | |
| 1995 | Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak | Site-directed mutagenesis of arginine... | |
| 1995 | Jan Balzarini | Novel concepts in the treatment of hu... | |
| 1995 | M Sala, S Wain-Hobson, F Schaeffer | Human immunodeficiency virus type 1 r... | |
| 1995 | L M Mansky, H M Temin | Lower in vivo mutation rate of human ... | |
| 1995 | N M Gray, C L Marr, C R Penn, J M Cameron, R C Bethell | The intracellular phosphorylation of ... | |
| 1995 | P N Yadav, J S Yadav, Mukund J Modak | Nucleoside drug resistance in HIV-1 r... | |
| 1995 | R A Spence, W M Kati, Karen S Anderson, Kenneth A Johnson | Mechanism of inhibition of HIV-1 reve... | |
| 1995 | R R Vyas, A K Basu | DNA polymerase action on an oligonucl... | |
| 1995 | Baek Kim, Lawrence A Loeb | Human immunodeficiency virus reverse ... | |
| 1995 | Z Gu, Yudong Quan, Zhongjie Li, E.J. Arts, Mark A. Wainberg | Effects of non-nucleoside inhibitors ... | |
| 1995 | M I Anazodo, H Salomon, A D Friesen, Mark A. Wainberg, J A Wright | Antiviral activity and protection of ... | |
| 1995 | E.J. Arts, Zhongjie Li, Mark A. Wainberg | Analysis of Primer Extension and the ... | |
| 1995 | V McKiel, Z Gu, Mark A. Wainberg, J Hiscott | Inhibition of human immunodeficiency ... | |
| 1995 | Ronald S Fletcher, Dominique Arion, G Borkow, Mark A. Wainberg, G I Dmitrienko, Michael A. Parniak | Synergistic inhibition of HIV-1 rever... | |
| 1995 | Mark A. Wainberg, Z Gu | Targeting HIV reverse transcriptase i... | |
| 1995 | R J Germinario, T DeSantis, Mark A. Wainberg | Insulin-like growth factor 1 and insu... | |
| 1995 | Z Gu, E.J. Arts, Michael A. Parniak, Mark A. Wainberg | Mutated K65R recombinant reverse tran... | |
| 1995 | M I Anazodo, Mark A. Wainberg, A D Friesen, J A Wright | Sequence-specific inhibition of gene ... | |
| 1995 | Mark A. Wainberg, Z Gu, H Salomon, E.J. Arts, Lawrence Kleiman, Michael A. Parniak, N Morin | [Molecular basis and clinical signifi... | |
| 1995 | M Ghosh, K J Howard, Craig E Cameron, Stephen J Benkovic, Stephen H Hughes, Stuart F J Le Grice | Truncating alpha-helix E' of p66 huma... | |
| 1995 | T Shirasaka, M F Kavlick, Takayuki Ueno, W Y Gao, E Kojima, M L Alcaide, S Chokekijchai, B M Roy, Edward Arnold, R Yarchoan | Emergence of human immunodeficiency v... | |
| 1995 | Brendan A Larder, S D Kemp, P Richard Harrigan | Potential mechanism for sustained ant... | |
| 1995 | Rob Schuurman, Monique Nijhuis, R van Leeuwen, P Schipper, D de Jong, P Collis, Sven A Danner, J Mulder, C Loveday, C Christopherson | Rapid changes in human immunodeficien... | |
| 1995 | K Rittinger, G Divita, R S Goody | Human immunodeficiency virus reverse ... | |
| 1995 | Matthias Götte, S Fackler, T Hermann, E Perola, Luciano Cellai, H J Gross, Stuart F J Le Grice, H Heumann | HIV-1 reverse transcriptase-associate... | |
| 1995 | Ronald S Fletcher, K Syed, S Mithani, G I Dmitrienko, Michael A. Parniak | Carboxanilide derivative non-nucleosi... | |
| 1995 | M Jaju, William A Beard, Samuel H Wilson | Human immunodeficiency virus type 1 r... | |
| 1995 | Hongxing Zhang, Yang Zhang, T Spicer, D Henrard, B J Poiesz | Nascent human immunodeficiency virus ... | |
| 1995 | Silvio Spadari, Giovanni Maga, A Verri, A Bendiscioli, L Tondelli, M Capobianco, F Colonna, A Garbesi, Federico Focher | Lack of stereospecificity of some cel... | |
| 1995 | Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari | Stereospecificity of human DNA polyme... | |
| 1995 | Baek Kim, Lawrence A Loeb | A screen in Escherichia coli for nucl... | |
| 1995 | Edward Arnold, Jianping Ding, Stephen H Hughes, Z Hostomsky | Structures of DNA and RNA polymerases... | |
| 1995 | Katarzyna Bebenek, William A Beard, J R Casas-Finet, H R Kim, Thomas A Darden, Samuel H Wilson, Thomas A Kunkel | Reduced frameshift fidelity and proce... | |
| 1995 | B M Wöhrl, C Tantillo, Edward Arnold, Stuart F J Le Grice | An expanded model of replicating huma... | |
| 1995 | P H Patel, A Jacobo-Molina, Jianping Ding, C Tantillo, Art D Clark, R Raag, R G Nanni, Stephen H Hughes, Edward Arnold | Insights into DNA polymerization mech... | |
| 1995 | Jörg-Peter Kleim, R Bender, R Kirsch, C Meichsner, A Paessens, M Rösner, H Rübsamen-Waigmann, R Kaiser, M Wichers, K E Schneweis | Preclinical evaluation of HBY 097, a ... | |
| 1995 | Marilyn B Kroeger Smith, C A Rouzer, L A Taneyhill, N A Smith, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, H Moereels, Luc Koymans, Edward Arnold | Molecular modeling studies of HIV-1 r... | |
| 1995 | Robert W Buckheit, V Fliakas-Boltz, S Yeagy-Bargo, O Weislow, D L Mayers, Paul L Boyer, Stephen H Hughes, B C Pan, S H Chu, J P Bader | Resistance to 1-[(2-hydroxyethoxy)met... | |
| 1995 | Haijiang Zhang, L Vrang, K Bäckbro, P Lind, Christer Sahlberg, Torsten Unge, Bo Oberg | Inhibition of human immunodeficiency ... | |
| 1995 | Robert W Buckheit, T L Kinjerski, V Fliakas-Boltz, J D Russell, T L Stup, L A Pallansch, W G Brouwer, D C Dao, W A Harrison, R J Schultz | Structure-activity and cross-resistan... | |
| 1995 | Jan Balzarini, María-Jesús Pérez-Pérez, S Vélazquez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson | Suppression of the breakthrough of hu... | |
| 1995 | M Hottiger, K Gramatikoff, O Georgiev, C Chaponnier, W Schaffner, Ulrich Hübscher | The large subunit of HIV-1 reverse tr... | |
| 1995 | J Horlacher, M Hottiger, Vladimir N Podust, Ulrich Hübscher, Steven A Benner | Recognition by viral and cellular DNA... | |
| 1995 | S D Young, S F Britcher, L O Tran, L S Payne, W C Lumma, T A Lyle, J R Huff, P S Anderson, David B Olsen, Steven S Carroll | L-743, 726 (DMP-266): a novel, highly... | |
| 1995 | Katarzyna Bebenek, Thomas A Kunkel | Analyzing fidelity of DNA polymerases. | Frameshift Error Rate,Overall Error Rate,All properties |
| 1995 | G Tachedjian, D J Hooker, A D Gurusinghe, H Bazmi, N J Deacon, J Mellors, C Birch, J Mills | Characterisation of foscarnet-resista... | |
| 1995 | Takayuki Ueno, T Shirasaka, Hiroyuki Mitsuya | Enzymatic characterization of human i... | |
| 1995 | John W Mellors, Holly Z Bazmi, Raymond F Schinazi, B M Roy, Y Hsiou, Edward Arnold, J Weir, D L Mayers | Novel mutations in reverse transcript... | |
| 1995 | Jingshan Ren, R Esnouf, E Garman, D Somers, C Ross, I Kirby, J Keeling, G Darby, Y Jones, David I Stuart | High resolution structures of HIV-1 R... | |
| 1995 | Jianping Ding, Kalyan Das, H Moereels, Luc Koymans, Koen Andries, Paul A J Janssen, Stephen H Hughes, Edward Arnold | Structure of HIV-1 RT/TIBO R 86183 co... | |
| 1995 | R Esnouf, Jingshan Ren, C Ross, Y Jones, D Stammers, David I Stuart | Mechanism of inhibition of HIV-1 reve... | |
| 1995 | Jingshan Ren, R Esnouf, A Hopkins, C Ross, Y Jones, D Stammers, David I Stuart | The structure of HIV-1 reverse transc... | |
| 1995 | Jianping Ding, Kalyan Das, C Tantillo, Weiming Zhang, Arthur D Clark, S Jessen, Xiaoqing Lu, Y Hsiou, A Jacobo-Molina, Koen Andries | Structure of HIV-1 reverse transcript... | |
| 1995 | Erik De Clercq, Jan Balzarini | Knocking out human immunodeficiency v... | |
| 1995 | Jan Balzarini, M Weeger, María-José Camarasa, Erik De Clercq, K Uberla | Sensitivity/resistance profile of a s... | |
| 1995 | Jan Balzarini, W G Brouwer, E E Felauer, Erik De Clercq, Anna Karlsson | Activity of various thiocarboxanilide... | |
| 1995 | Sonsoles Velázquez, R Alvarez, Ana San-Félix, M L Jimeno, Erik De Clercq, Jan Balzarini, María-José Camarasa | Synthesis and anti-HIV activity of [A... | |
| 1995 | Jan Balzarini, Masanori Baba, Erik De Clercq | Differential activities of 1-[(2-hydr... | |
| 1995 | Y Törnevik, B Ullman, Jan Balzarini, B Wahren, Staffan Eriksson | Cytotoxicity of 3'-azido-3'-deoxythym... | |
| 1994 | Jan Balzarini, Anna Karlsson, C Meichsner, A Paessens, G Riess, Erik De Clercq, Jörg-Peter Kleim | Resistance pattern of human immunodef... | |
| 1994 | T Hermann, T Meier, Matthias Götte, H Heumann | The 'helix clamp' in HIV-1 reverse tr... | |
| 1994 | Rudi Pauwels, Koen Andries, Zeger Debyser, Michael J Kukla, Dominique Schols, H J Breslin, R Woestenborghs, J Desmyter, M A Janssen, Erik De Clercq | New tetrahydroimidazo[4,5,1-jk][1,4]-... | |
| 1994 | S F Lacey, Brendan A Larder | Novel mutation (V75T) in human immuno... | |
| 1994 | Erik De Clercq | How to overcome resistance of HIV-1 t... | |
| 1994 | Erik De Clercq | New developments in the chemotherapy ... | |
| 1994 | P S Jacques, B M Wöhrl, M Ottmann, J L Darlix, Stuart F J Le Grice | Mutating the "primer grip" of p66 HIV... | |
| 1994 | Torsten Unge, S Knight, R Bhikhabhai, S Lövgren, Z Dauter, K Wilson, B Strandberg | 2.2 A resolution structure of the ami... | |
| 1994 | Masanori Baba, S Shigeta, S Yuasa, H Takashima, K Sekiya, M Ubasawa, Hiromichi Tanaka, T Miyasaka, R T Walker, Erik De Clercq | Preclinical evaluation of MKC-442, a ... | |
| 1994 | Erik De Clercq | HIV resistance to reverse transcripta... | |
| 1994 | J Mak, M Jiang, Mark A. Wainberg, M L Hammarskjöld, D Rekosh, Lawrence Kleiman | Role of Pr160gag-pol in mediating the... | |
| 1994 | Z Gu, Q Gao, H Fang, Michael A. Parniak, Bluma G Brenner, Mark A. Wainberg | Identification of novel mutations tha... | |
| 1994 | E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg | Mature reverse transcriptase (p66/p51... | |
| 1994 | S Zinnen, J C Hsieh, P Modrich | Misincorporation and mispaired primer... | |
| 1994 | L Mercure, B J Brenner, D Phaneuf, C Tsoukas, Mark A. Wainberg | Effect of 3'-azido-3'-deoxythymidine ... | |
| 1994 | Paul L Boyer, C Tantillo, A Jacobo-Molina, R G Nanni, Jianping Ding, Edward Arnold, Stephen H Hughes | Sensitivity of wild-type human immuno... | |
| 1994 | E.J. Arts, Xincang Li, Z Gu, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg | Comparison of deoxyoligonucleotide an... | |
| 1994 | M Smith, H Salomon, Mark A. Wainberg | Development and significance of nucle... | |
| 1994 | S J Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, A J Chirino, J M Friedman, P A Rice, Thomas A Steitz | Structure of the binding site for non... | |
| 1994 | V W Byrnes, E A Emini, W A Schleif, J H Condra, C L Schneider, W J Long, J A Wolfgang, D J Graham, L Gotlib, A J Schlabach | Susceptibilities of human immunodefic... | |
| 1994 | E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg | DNA found in human immunodeficiency v... | |
| 1994 | Z Gu, Ronald S Fletcher, E.J. Arts, Mark A. Wainberg, Michael A. Parniak | The K65R mutant reverse transcriptase... | |
| 1994 | M R Sawaya, H Pelletier, A Kumar, Samuel H Wilson, J Kraut | Crystal structure of rat DNA polymera... | |
| 1994 | P N Yadav, J S Yadav, Edward Arnold, Mukund J Modak | A computer-assisted analysis of conse... | |
| 1994 | J Ji, Lawrence A Loeb | Fidelity of HIV-1 reverse transcripta... | |
| 1994 | Jan Balzarini, Jörg-Peter Kleim, G Riess, María-José Camarasa, Erik De Clercq, Anna Karlsson | Sensitivity of (138 Glu-->Lys) mutate... | |
| 1994 | M H Nguyen, Raymond F Schinazi, C Shi, N M Goudgaon, P M McKenna, John W Mellors | Resistance of human immunodeficiency ... | |
| 1994 | S Loya, M Bakhanashvili, R Tal, Stephen H Hughes, Paul L Boyer, A Hizi | Enzymatic properties of two mutants o... | |
| 1994 | Jan Balzarini, Anna Karlsson, V V Sardana, E A Emini, María-José Camarasa, Erik De Clercq | Human immunodeficiency virus 1 (HIV-1... | |
| 1994 | A-M Vandamme, Zeger Debyser, Rudi Pauwels, K De Vreese, P Goubau, M Youle, B Gazzard, P A Stoffels, G F Cauwenbergh, J Anne | Characterization of HIV-1 strains iso... | |
| 1994 | H Jonckheere, J M Taymans, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, J Desmyter, Erik De Clercq, J Anné | Resistance of HIV-1 reverse transcrip... | |
| 1994 | G Gosselin, Raymond F Schinazi, J P Sommadossi, C Mathé, M C Bergogne, A M Aubertin, A Kirn, J L Imbach | Anti-human immunodeficiency virus act... | |
| 1994 | Myron F Goodman, H Cai, Linda B Bloom, R Eritja | Nucleotide insertion and primer exten... | |
| 1994 | Paul L Boyer, Andrea L Ferris, Patrick K Clark, J Whitmer, P Frank, C Tantillo, Edward Arnold, Stephen H Hughes | Mutational analysis of the fingers an... | |
| 1994 | J Ji, Jean-Sébastien Hoffmann, L Loeb | Mutagenicity and pausing of HIV rever... | |
| 1994 | I Kang, Jing-Houng Wang | Design of structure-based reverse tra... | |
| 1994 | C Tantillo, Jianping Ding, A Jacobo-Molina, R G Nanni, Paul L Boyer, Stephen H Hughes, Rudi Pauwels, Koen Andries, Paul A J Janssen, Edward Arnold | Locations of anti-AIDS drug binding s... | |
| 1994 | William A Beard, Samuel H Wilson | Site-directed mutagenesis of HIV reve... | |
| 1994 | M Hottiger, Vladimir N Podust, R L Thimmig, C McHenry, Ulrich Hübscher | Strand displacement activity of the h... | |
| 1994 | M D Delahunty, Samuel H Wilson, R L Karpel | Studies on primer binding of HIV-1 re... | |
| 1994 | Douglas D Richman, D Havlir, J Corbeil, D Looney, C Ignacio, S A Spector, J Sullivan, S Cheeseman, K Barringer, D Pauletti | Nevirapine resistance mutations of hu... | |
| 1994 | T Rubinek, S Loya, M Shaharabany, Stephen H Hughes, Patrick K Clark, A Hizi | The catalytic properties of the rever... | |
| 1994 | M A Fisher, P N Yadav, J Yadav, D Kristol, Edward Arnold, Mukund J Modak | Identification of a pharmacophore for... | |
| 1994 | Paul L Boyer, Jianping Ding, Edward Arnold, Stephen H Hughes | Subunit specificity of mutations that... | |
| 1994 | H Pelletier, M R Sawaya, A Kumar, Samuel H Wilson, J Kraut | Structures of ternary complexes of ra... | |
| 1994 | S V Doronin, M I Dobrikov, M Buckle, P Roux, H Buc, Olga I Lavrik | Affinity modification of human immuno... | |
| 1994 | J Jäger, S J Smerdon, Jianhong Wang, D C Boisvert, Thomas A Steitz | Comparison of three different crystal... | |
| 1994 | A Okruszek, M Olesiak, Jan Balzarini | The synthesis of nucleoside 5'-O-(1,1... | |
| 1994 | Jianping Ding, A Jacobo-Molina, C Tantillo, Xiaoqing Lu, R G Nanni, Edward Arnold | Buried surface analysis of HIV-1 reve... | |
| 1993 | Paul L Boyer, M J Currens, James B McMahon, M R Boyd, Stephen H Hughes | Analysis of nonnucleoside drug-resist... | |
| 1993 | A Hizi, R Tal, M Shaharabany, M J Currens, M R Boyd, Stephen H Hughes, James B McMahon | Specific inhibition of the reverse tr... | |
| 1993 | R L Thimmig, Charles S McHenry | Human immunodeficiency virus reverse ... | |
| 1993 | H Cai, Linda B Bloom, R Eritja, Myron F Goodman | Kinetics of deoxyribonucleotide inser... | |
| 1993 | S St Luce, E Arts, R Geleziunas, S Bour, Mark A. Wainberg | Infection of human monocyte-derived m... | |
| 1993 | Xincang Li, E Amandoron, Mark A. Wainberg, Michael A. Parniak | Generation and characterization of mu... | |
| 1993 | Mark A. Wainberg, H Salomon, Bonnie Spira, L Mercure, J Wainberg, K Nagai, Z Bentwich, J Montaner | HIV resistance to anti-viral drugs. | |
| 1993 | Mark A. Wainberg, Z Gu, Q Gao, E Arts, R Geleziunas, S Bour, R Beaulieu, C Tsoukas, J Singer, J Montaner | Clinical correlates and molecular bas... | |
| 1993 | R Goel, William A Beard, A Kumar, J R Casas-Finet, M P Strub, S J Stahl, M S Lewis, Katarzyna Bebenek, S P Becerra, Thomas A Kunkel | Structure/function studies of HIV-1(1... | |
| 1993 | J Abbotts, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson | Mechanism of HIV-1 reverse transcript... | |
| 1993 | Katarzyna Bebenek, J Abbotts, Samuel H Wilson, Thomas A Kunkel | Error-prone polymerization by HIV-1 r... | |
| 1993 | S P Becerra, A Kumar, Samuel H Wilson | Expression of polypeptides of human i... | |
| 1993 | A Kumar, H R Kim, Robert W Sobol, S P Becerra, B J Lee, D L Hatfield, R J Suhadolnik, Samuel H Wilson | Mapping of nucleic acid binding in pr... | |
| 1993 | William A Beard, Samuel H Wilson | Kinetic analysis of template.primer i... | |
| 1993 | Robert W Sobol, W L Fisher, N L Reichenbach, A Kumar, William A Beard, Samuel H Wilson, R Charubala, W Pfleiderer, R J Suhadolnik | HIV-1 reverse transcriptase: inhibiti... | |
| 1993 | C T Wang, Yongqing Zhang, J McDermott, E Barklis | Conditional infectivity of a human im... | |
| 1993 | Svetlana N Khodyreva, Vladimir N Podust, D S Sergeev, E M Ivanova, E I Frolova, A A Koshkin, T S Godovikova, V F Zarytova, Miria Ricchetti, Olga I Lavrik | Comparison of interactions of 5'-deri... | |
| 1993 | S Kawa, A Kumar, J S Smith, S P Becerra, William A Beard, Samuel H Wilson, E B Thompson | Expression and purification of the HI... | |
| 1993 | T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley | A mutation in reverse transcriptase o... | |
| 1993 | Jörg-Peter Kleim, R Bender, U M Billhardt, C Meichsner, G Riess, M Rösner, I Winkler, A Paessens | Activity of a novel quinoxaline deriv... | |
| 1993 | G Maass, U Immendoerfer, B Koenig, U Leser, B Mueller, R Goody, E Pfaff | Viral resistance to the thiazolo-iso-... | |
| 1993 | Jan Balzarini, Anna Karlsson, A-M Vandamme, María-Jesús Pérez-Pérez, Haijiang Zhang, L Vrang, Bo Oberg, K Bäckbro, Torsten Unge, Ana San-Félix | Human immunodeficiency virus type 1 (... | |
| 1993 | Jan Balzarini, Sonsoles Velazquez, A San-Felix, Anna Karlsson, M J Perez-Perez, María-José Camarasa, Erik De Clercq | Human immunodeficiency virus type 1-s... | |
| 1993 | Jan Balzarini, Anna Karlsson, Erik De Clercq | Human immunodeficiency virus type 1 d... | |
| 1993 | M S Saag, E A Emini, O L Laskin, J Douglas, W I Lapidus, W A Schleif, R J Whitley, C Hildebrand, V W Byrnes, John C Kappes | A short-term clinical evaluation of L... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, L Vrang, J Walbers, Haijiang Zhang, Bo Oberg, A-M Vandamme, María-José Camarasa, Erik De Clercq | HIV-1-specific reverse transcriptase ... | |
| 1993 | John W Mellors, G J Im, Enzo Tramontano, S R Winkler, D J Medina, Ginger E Dutschman, Holly Z Bazmi, G Piras, C J Gonzalez, Yung-Chi Cheng | A single conservative amino acid subs... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, W G Tarpley, Erik De Clercq | Treatment of human immunodeficiency v... | |
| 1993 | Kristin A Eckert, Thomas A Kunkel | Fidelity of DNA synthesis catalyzed b... | Cloned or native,Full length or truncated,Specific Activity,3-5' exo,Nucleotide Substitution Rate,All properties |
| 1993 | M Tisdale, S D Kemp, N R Parry, Brendan A Larder | Rapid in vitro selection of human imm... | |
| 1993 | J L Martin, J E Wilson, R L Haynes, Phillip A Furman | Mechanism of resistance of human immu... | |
| 1993 | Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg | The same mutation that encodes low-le... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, Erik De Clercq | Knocking-out concentrations of HIV-1-... | |
| 1993 | J C Hsieh, S Zinnen, P Modrich | Kinetic mechanism of the DNA-dependen... | |
| 1993 | A Jacobo-Molina, Jianping Ding, R G Nanni, Arthur D Clark, Xiaoqing Lu, C Tantillo, R L Williams, G Kamer, Andrea L Ferris, Patrick K Clark | Crystal structure of human immunodefi... | |
| 1993 | W Y Gao, A Cara, R C Gallo, F Lori | Low levels of deoxynucleotides in per... | |
| 1993 | Johan Neyts, F Stals, C Bruggeman, Erik De Clercq | Activity of the anti-HIV agent 9-(2-p... | |
| 1993 | Erik De Clercq | HIV-1-specific RT inhibitors: highly ... | |
| 1993 | Zeger Debyser, K De Vreese, P P Knops-Gerrits, V Baekelandt, R Bhikhabhai, B Strandberg, Rudi Pauwels, J Anné, J Desmyter, Erik De Clercq | Kinetics of different human immunodef... | |
| 1993 | Erik De Clercq | Antiviral agents: characteristic acti... | |
| 1993 | Thomas A Steitz, S Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, J M Friedman, Lorena S Beese, P A Rice | Two DNA polymerases: HIV reverse tran... | |
| 1993 | D Chattopadhyay, B C Finzel, S H Munson, D B Evans, S K Sharma, N A Strakalaitus, D P Brunner, F M Eckenrode, Z Dauter, C Betzel, H M Einspahr | Crystallographic analyses of an activ... | |
| 1993 | Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors | Characterization of human immunodefic... | |
| 1993 | M S Chen, R T Suttmann, E Papp, P D Cannon, M J McRoberts, C Bach, William C Copeland, Teresa S-F Wang | Selective action of 4'-azidothymidine... | |
| 1993 | R Sousa, Y J Chung, J P Rose, B C Wang | Crystal structure of bacteriophage T7... | |
| 1993 | Myron F Goodman, S Creighton, Linda B Bloom, John Petruska | Biochemical basis of DNA replication ... | |
| 1993 | G T Tan, A Wickramasinghe, S Verma, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan | Sulfonic acid polymers are potent inh... | |
| 1992 | C S Crumpacker | Mechanism of action of foscarnet agai... | |
| 1992 | M Jiang, J Mak, Mark A. Wainberg, Michael A. Parniak, E Cohen, Lawrence Kleiman | Variable tRNA content in HIV-1IIIB. | |
| 1992 | J C Boyer, Katarzyna Bebenek, Thomas A Kunkel | Unequal human immunodeficiency virus ... | |
| 1992 | Paul L Boyer, Andrea L Ferris, Stephen H Hughes | Mutational analysis of the fingers do... | |
| 1992 | F Boulerice, R Geleziunas, S Bour, H L Li, M D'Addario, A Roulston, J Hiscott, Mark A. Wainberg | Differential susceptibilities of U-93... | |
| 1992 | Mark A. Wainberg, R G Margolese | Strategies in the treatment of AIDS a... | |
| 1992 | A Hosmalin, S Kumar, D Barnd, R Houghten, G E Smith, Stephen H Hughes, J A Berzofsky | Immunization with soluble protein-pul... | |
| 1992 | N Yamamoto, Dominique Schols, Erik De Clercq, Zeger Debyser, Rudi Pauwels, Jan Balzarini, H Nakashima, Masanori Baba, M Hosoya, Robert Snoeck | Mechanism of anti-human immunodeficie... | |
| 1992 | J P Ji, Lawrence A Loeb | Fidelity of HIV-1 reverse transcripta... | |
| 1992 | S Loya, R Tal, Stephen H Hughes, A Hizi | The effects of cysteine mutations on ... | |
| 1992 | Zeger Debyser, K De Vreese, Rudi Pauwels, N Yamamoto, J Anné, Erik De Clercq, J Desmyter | Differential inhibitory effects of TI... | |
| 1992 | Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, Masanori Baba, J Desmyter, Erik De Clercq | Kinetics of inhibition of endogenous ... | |
| 1992 | K De Vreese, Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, J Desmyter, Erik De Clercq, J Anné | Resistance of human immunodeficiency ... | |
| 1992 | Erik De Clercq | HIV inhibitors targeted at the revers... | |
| 1992 | Erik De Clercq | New perspectives for the chemotherapy... | |
| 1992 | Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Y Engelborghs, Paul A J Janssen, Erik De Clercq | Allosteric inhibition of human immuno... | |
| 1992 | Zeger Debyser, Rudi Pauwels, Koen Andries, Erik De Clercq | Specific HIV-1 reverse transcriptase ... | |
| 1992 | M M Huang, Norman Arnheim, Myron F Goodman | Extension of base mispairs by Taq DNA... | |
| 1992 | Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg | Novel mutation in the human immunodef... | |
| 1992 | Z Hostomsky, Z Hostomska, T B Fu, J Taylor | Reverse transcriptase of human immuno... | |
| 1992 | P Kellam, Charles A B Boucher, Brendan A Larder | Fifth mutation in human immunodeficie... | |
| 1992 | S F Lacey, J E Reardon, E S Furfine, Thomas A Kunkel, Katarzyna Bebenek, Kristin A Eckert, S D Kemp, Brendan A Larder | Biochemical studies on the reverse tr... | |
| 1992 | William C Copeland, M S Chen, Teresa S-F Wang | Human DNA polymerases alpha and beta ... | |
| 1992 | G T Tan, J F Miller, A D Kinghorn, Stephen H Hughes, J M Pezzuto | HIV-1 and HIV-2 reverse transcriptase... | |
| 1992 | Brendan A Larder | 3'-Azido-3'-deoxythymidine resistance... | |
| 1992 | Edward Arnold, A Jacobo-Molina, R G Nanni, R L Williams, Xiaoqing Lu, Jianping Ding, Art D Clark, A Zhang, Andrea L Ferris, Patrick K Clark | Structure of HIV-1 reverse transcript... | |
| 1992 | A Basu, S Basu, Mukund J Modak | Structure-activity analyses of HIV-1 ... | |
| 1992 | Tsuyoshi Yamaguchi, Shunji Izuta, Motoshi Suzuki, Shonen Yoshida, Akio Matsukage, Mineo Saneyoshi | Inhibitory effects of 2'-deoxy-5-styr... | |
| 1992 | R L Mitina, S V Doronin, M I Dobrikov, D R Tabatadze, A S Levina, Olga I Lavrik | Human immunodeficiency virus type 1 r... | |
| 1992 | L A Kohlstaedt, Thomas A Steitz | Reverse transcriptase of human immuno... | |
| 1992 | J A Coates, Nick Cammack, H J Jenkinson, I M Mutton, B A Pearson, R Storer, J M Cameron, C R Penn | The separated enantiomers of 2'-deoxy... | |
| 1992 | J A Coates, Nick Cammack, H J Jenkinson, A J Jowett, M I Jowett, B A Pearson, C R Penn, P L Rouse, K C Viner, J M Cameron | (-)-2'-deoxy-3'-thiacytidine is a pot... | |
| 1992 | D L Mayers, F E McCutchan, E E Sanders-Buell, L I Merritt, S Dilworth, A K Fowler, C A Marks, N M Ruiz, Douglas D Richman, C R Roberts | Characterization of HIV isolates aris... | |
| 1992 | John W Mellors, Ginger E Dutschman, G J Im, Enzo Tramontano, S R Winkler, Yung-Chi Cheng | In vitro selection and molecular char... | |
| 1992 | Hong Yu, Myron F Goodman | Comparison of HIV-1 and avian myelobl... | |
| 1992 | W M Kati, Kenneth A Johnson, L F Jerva, Karen S Anderson | Mechanism and fidelity of HIV reverse... | |
| 1992 | J J DeStefano, R G Buiser, L M Mallaber, P J Fay, Robert A Bambara | Parameters that influence processive ... | RT,Full length or truncated,Specific Activity,Processivity,Molecular Weight,RNase H,All properties |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velazquez, María-José Camarasa, Erik De Clercq | [2',5'-Bis-O-(tert-butyldimethylsilyl... | |
| 1992 | V V Sardana, E A Emini, L Gotlib, D J Graham, D W Lineberger, W J Long, A J Schlabach, J A Wolfgang, J H Condra | Functional analysis of HIV-1 reverse ... | |
| 1992 | J E Reardon | Human immunodeficiency virus reverse ... | |
| 1992 | A Basu, K K Ahluwalia, S Basu, Mukund J Modak | Identification of the primer binding ... | |
| 1992 | G T Tan, A Wickramasinghe, S Verma, R Singh, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan | Potential anti-AIDS naphthalenesulfon... | |
| 1992 | M Bakhanashvili, A Hizi | Fidelity of the reverse transcriptase... | RT,3-5' exo,All properties |
| 1992 | M B Vasudevachari, C Battista, H C Lane, M C Psallidopoulos, B Zhao, J Cook, J R Palmer, D L Romero, W G Tarpley, N P Salzman | Prevention of the spread of HIV-1 inf... | |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Dominique Schols, CF Perno, A-M Vandamme, María-José Camarasa, Erik De Clercq | 2',5'-Bis-O-(tert-butyldimethylsilyl)... | |
| 1992 | Q Gao, Z X Gu, Michael A. Parniak, X G Li, Mark A. Wainberg | In vitro selection of variants of hum... | |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, I C Bathurst, P J Barr, Erik De Clercq | Kinetics of inhibition of human immun... | |
| 1992 | Shunji Izuta, N Shimada, Masatoshi Kitagawa, Motoshi Suzuki, K Kojima, Shonen Yoshida | Inhibitory effects of triphosphate de... | |
| 1992 | L A Kohlstaedt, Jianhong Wang, J M Friedman, P A Rice, Thomas A Steitz | Crystal structure at 3.5 A resolution... | |
| 1992 | J Abbotts, Samuel H Wilson | Inhibitors of HIV-1 reverse transcrip... | |
| 1992 | Alberto Bergamini, CF Perno, Jan Balzarini, M Capozzi, Luciana Marinelli, G Milanese, C D Pesce, R Calió, G Rocchi | Selective inhibition of HIV replicati... | |
| 1992 | L Ding, Jan Balzarini, Dominique Schols, B Meunier, Erik De Clercq | Anti-human immunodeficiency virus eff... | |
| 1992 | V Gopalakrishnan, J A Peliska, Stephen J Benkovic | Human immunodeficiency virus type 1 r... | RT,Terminal Transferase,RNase H,All properties |
| 1992 | I I Fedorov, E M Kazmina, N A Novicov, Galina V Gurskaya, A V Bochkarev, M V Jasko, L S Victorova, M K Kukhanova, Jan Balzarini, Erik De Clercq | 3'-C-branched 2'-deoxy-5-methyluridin... | |
| 1992 | J A Peliska, Stephen J Benkovic | Mechanism of DNA strand transfer reac... | |
| 1991 | F Boulerice, X G Li, A Lvovich, Mark A. Wainberg | Recovery of infectious human immunode... | |
| 1991 | Jan Balzarini, Antonin Holy, J Jindrich, H Dvorakova, Z Hao, Robert Snoeck, Piet Herdewijn, D G Johns, Erik De Clercq | 9-[(2RS)-3-fluoro-2-phosphonylmethoxy... | |
| 1991 | P Hafkemeyer, K Neftel, R Hobi, A Pfaltz, H Lutz, K Lüthi, Federico Focher, Silvio Spadari, Ulrich Hübscher | HP 0.35, a cephalosporin degradation ... | RT,RNase H,All properties |
| 1991 | R S Goody, B Müller, Tobias Restle | Factors contributing to the inhibitio... | |
| 1991 | Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Michael Kukla, Paul A J Janssen, Erik De Clercq | An antiviral target on reverse transc... | |
| 1991 | E S Furfine, J E Reardon | Reverse transcriptase.RNase H from th... | RT,All properties |
| 1991 | Brendan A Larder, K E Coates, S D Kemp | Zidovudine-resistant human immunodefi... | |
| 1991 | D Richman, C K Shih, I Lowy, J Rose, P Prodanovich, S Goff, J Griffin | Human immunodeficiency virus type 1 m... | |
| 1991 | E B Kopp, J J Miglietta, A G Shrutkowski, C K Shih, P M Grob, M T Skoog | Steady state kinetics and inhibition ... | KM,kcat,All properties |
| 1991 | M H St Clair, J L Martin, G Tudor-Williams, M C Bach, C L Vavro, D M King, P Kellam, S D Kemp, Brendan A Larder | Resistance to ddI and sensitivity to ... | |
| 1991 | A DeVico, R C Montelaro, R C Gallo, M G Sarngadharan | Purification and partial characteriza... | RT,Full length or truncated,3-5' exo,Nucleotide Substitution Rate,RNase H,All properties |
| 1991 | J H Nunberg, W A Schleif, E J Boots, J A O'Brien, J C Quintero, J M Hoffman, E A Emini, M E Goldman | Viral resistance to human immunodefic... | |
| 1991 | Olga I Lavrik | Oligonucleotides and their derivative... | |
| 1991 | S P Becerra, A Kumar, M S Lewis, S G Widen, J Abbotts, E M Karawya, Stephen H Hughes, J Shiloach, Samuel H Wilson, M S Lewis | Protein-protein interactions of HIV-1... | |
| 1991 | Robert W Sobol, R J Suhadolnik, A Kumar, B J Lee, D L Hatfield, Samuel H Wilson | Localization of a polynucleotide bind... | |
| 1991 | J G Baillon, N T Nashed, A Kumar, Samuel H Wilson, Donald M Jerina | A leucine zipper-like motif may media... | |
| 1991 | J Abbotts, M Jaju, Samuel H Wilson | Thermodynamics of A:G mismatch poly(d... | |
| 1991 | A Hizi, R Tal, Stephen H Hughes | Mutational analysis of the DNA polyme... | |
| 1991 | A S De Groot, M Clerici, A Hosmalin, Stephen H Hughes, D Barnd, C W Hendrix, R Houghten, G M Shearer, J A Berzofsky | Human immunodeficiency virus reverse ... | |
| 1991 | Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, R T Walker, S Mori | Highly potent and selective inhibitio... | |
| 1991 | Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, H Nakashima, S Mori | Potent and selective inhibition of hu... | |
| 1991 | Erik De Clercq | Chemotherapy of the acquired immune d... | |
| 1991 | Mark Cushman, S Kanamathareddy, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen | Synthesis and anti-HIV activities of ... | |
| 1991 | Mark Cushman, P L Wang, S H Chang, C Wild, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen | Preparation and anti-HIV activities o... | |
| 1991 | G T Tan, A D Kinghorn, Stephen H Hughes, J M Pezzuto | Psychotrine and its O-methyl ether ar... | |
| 1991 | P R Johnson, T E Hamm, S Goldstein, S Kitov, V M Hirsch | The genetic fate of molecularly clone... | |
| 1991 | Mark A. Wainberg, R Rooke, M Tremblay, Xincang Li, Michael A. Parniak, Q Gao, X J Yao, C Tsoukas, J Montaner, M Fanning, J Ruedy | Clinical significance and characteriz... | |
| 1991 | A Jacobo-Molina, Edward Arnold | HIV reverse transcriptase structure-f... | |
| 1991 | K B Frank, G J Noll, E V Connell, I S Sim | Kinetic interaction of human immunode... | |
| 1991 | Stuart F J Le Grice, T Naas, B Wohlgensinger, O Schatz | Subunit-selective mutagenesis indicat... | |
| 1991 | J E Reardon, E S Furfine, N Cheng | Human immunodeficiency virus reverse ... | |
| 1991 | M Tisdale, T Schulze, Brendan A Larder, K Moelling | Mutations within the RNase H domain o... | |
| 1990 | V J Merluzzi, K D Hargrave, M Labadia, K Grozinger, M Skoog, J C Wu, C K Shih, K Eckner, S Hattox, J Adams | Inhibition of HIV-1 replication by a ... | |
| 1990 | Z Hao, D A Cooney, D Farquhar, CF Perno, K Zhang, R Masood, Y Wilson, N R Hartman, Jan Balzarini, D G Johns | Potent DNA chain termination activity... | |
| 1990 | Mark A. Wainberg, Bonnie Spira, G Bleau, R Thomas | Inactivation of human immunodeficienc... | |
| 1990 | Padmini S Kedar, J Abbotts, T Kovács, K Lesiak, P Torrence, Samuel H Wilson | Mechanism of HIV reverse transcriptas... | |
| 1990 | S P Becerra, G M Clore, A M Gronenborn, A R Karlström, S J Stahl, Samuel H Wilson, P T Wingfield | Purification and characterization of ... | |
| 1990 | Erik De Clercq | Selective virus inhibitors. | |
| 1990 | Erik De Clercq | Targets and strategies for the antivi... | |
| 1990 | M Tremblay, K Numazaki, H Goldman, Mark A. Wainberg | Infection of human thymic lymphocytes... | |
| 1990 | R Rooke, M Tremblay, Mark A. Wainberg | AZT (zidovudine) may act postintegrat... | |
| 1990 | Brendan A Larder, B Chesebro, Douglas D Richman | Susceptibilities of zidovudine-suscep... | |
| 1990 | Stuart F J Le Grice, F Grüninger-Leitch | Rapid purification of homodimer and h... | |
| 1990 | F Boulerice, Mark A. Wainberg | Inhibition by AZT of HIV-1 replicatio... | |
| 1990 | J E Reardon, W H Miller | Human immunodeficiency virus reverse ... | KM,kcat,All properties |
| 1990 | A M Barber, A Hizi, J V Maizel, Stephen H Hughes | HIV-1 reverse transcriptase: structur... | |
| 1990 | M Tremblay, K Numazaki, X G Li, M Gornitsky, J Hiscott, Mark A. Wainberg | Resistance to infection by HIV-1 of p... | |
| 1990 | M Ricchetti, H Buc | Reverse transcriptases and genomic va... | |
| 1990 | W E Müller, E Matthes, P Reuter, R Wenger, K Friese, Y Kuchino, H C Schröder | Effect of nonviable preparations from... | |
| 1990 | Andrea L Ferris, A Hizi, S D Showalter, S Pichuantes, L Babe, C S Craik, Stephen H Hughes | Immunologic and proteolytic analysis ... | |
| 1990 | A Hizi, Stephen H Hughes, M Shaharabany | Mutational analysis of the ribonuclea... | |
| 1990 | A I Glukhov, S A Gordeev, S V Vinogradov, V I Kiselev, V M Kramarov, O I Kiselev, E S Severin | Amplification of DNA sequences of Eps... | |
| 1990 | K J Williams, Lawrence A Loeb, M Fry | Synthesis of DNA by human immunodefic... | |
| 1989 | M Tremblay, M Gornitsky, Mark A. Wainberg | Active replication of human immunodef... | |
| 1989 | M Tremblay, Mark A. Wainberg | Susceptibility of EBV-carrying B cell... | |
| 1989 | A Hizi, A Barber, Stephen H Hughes | Effects of small insertions on the RN... | |
| 1989 | C Majumdar, C A Stein, J S Cohen, S Broder, Samuel H Wilson | Stepwise mechanism of HIV reverse tra... | |
| 1989 | B Müller, Tobias Restle, S Weiss, M Gautel, G Sczakiel, R S Goody | Co-expression of the subunits of the ... | |
| 1989 | Brendan A Larder, S D Kemp | Multiple mutations in HIV-1 reverse t... | |
| 1989 | H E Huber, J M McCoy, J S Seehra, Charles C Richardson | Human immunodeficiency virus 1 revers... | Processivity,3-5' exo,5-3' exo,KM,Kd,RNase H,All properties |
| 1989 | A Basu, R S Tirumalai, Mukund J Modak | Substrate binding in human immunodefi... | |
| 1989 | Masanori Baba, Hiromichi Tanaka, Erik De Clercq, Rudi Pauwels, Jan Balzarini, Dominique Schols, H Nakashima, CF Perno, R T Walker, T Miyasaka | Highly specific inhibition of human i... | |
| 1989 | Fred W Perrino, Bradley D Preston, L L Sandell, Lawrence A Loeb | Extension of mismatched 3' termini of... | |
| 1989 | M Ito, Masanori Baba, A Sato, K Hirabayashi, F Tanabe, S Shigeta, Erik De Clercq | Tumor necrosis factor enhances replic... | |
| 1989 | Erik De Clercq | Potential drugs for the treatment of ... | |
| 1989 | Masanori Baba, Dominique Schols, H Nakashima, Rudi Pauwels, G Parmentier, D K Meijer, Erik De Clercq | Selective activity of several cholic ... | |
| 1989 | Dominique Schols, Masanori Baba, Rudi Pauwels, Erik De Clercq | Flow cytometric method to demonstrate... | |
| 1989 | K Numazaki, X Q Bai, H Goldman, I Wong, Bonnie Spira, Mark A. Wainberg | Infection of cultured human thymic ep... | |
| 1988 | Masanori Baba, Dominique Schols, Rudi Pauwels, Jan Balzarini, Erik De Clercq | Fuchsin acid selectively inhibits hum... | |
| 1988 | J D Roberts, Katarzyna Bebenek, Thomas A Kunkel | The accuracy of reverse transcriptase... | |
| 1988 | Sujit Roy, L Fitz-Gibbon, L Poulin, Mark A. Wainberg | Infection of human monocytes/macropha... | |
| 1988 | A Hizi, C McGill, Stephen H Hughes | Expression of soluble, enzymatically ... | |
| 1988 | Masanori Baba, Rudi Pauwels, Jan Balzarini, J Arnout, J Desmyter, Erik De Clercq | Mechanism of inhibitory effect of dex... | |
| 1988 | M Tremblay, L Fitz-Gibbon, Mark A. Wainberg | Heterogeneity of HIV-1 replication an... | |
| 1988 | E M Wondrak, J Löwer, R Kurth | Inhibition of HIV-1 RNA-dependent DNA... | |
| 1988 | Erik De Clercq | Perspectives for the chemotherapy of ... | |
| 1988 | Bradley D Preston, B J Poiesz, Lawrence A Loeb | Fidelity of HIV-1 reverse transcriptase. | |
| 1987 | Brendan A Larder, D J Purifoy, K L Powell, G Darby | Site-specific mutagenesis of AIDS vir... | |
| 1987 | M Ito, H Nakashima, Masanori Baba, Rudi Pauwels, Erik De Clercq, S Shigeta, N Yamamoto | Inhibitory effect of glycyrrhizin on ... | |
| 1986 | M S Johnson, M A McClure, D F Feng, J Gray, R F Doolittle | Computer analysis of retroviral pol g... | |
| 1986 | F di Marzo Veronese, T D Copeland, A L DeVico, R Rahman, S Oroszlan, R C Gallo, M G Sarngadharan | Characterization of highly immunogeni... | |
| 1986 | M M Lightfoote, J E Coligan, T M Folks, A S Fauci, M A Martin, S Venkatesan | Structural characterization of revers... | |
| 1986 | H A Blough, Rudi Pauwels, Erik De Clercq, J Cogniaux, S Sprecher-Goldberger, L Thiry | Glycosylation inhibitors block the ex... | |
| 1985 | A D Hoffman, B Banapour, J A Levy | Characterization of the AIDS-associat... |
DNA sequence:
Protein information: Uniprot Q8Q292 search for HIV RT at UniProt
Sequence information: NCBI nucleotides European nucleotide archive