HIV RT
From
HIV
Welcome to the Polymerase Page
This page presents all the information in Polbase for HIV RT.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
HIV RT
is a family RT enzyme
from
HIV.
Selected Properties for HIV RT: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| No (4) | No (1) | 8.0e-06-4.7e-03 errors/bp (3) | 2.6e-05-3.2e-03 errors/bp (5) | 7.5e-05-8.0e-02 errors/bp (4) |
| Year | Authors | Title | Results by property |
|---|---|---|---|
| N Düzgünes, S Simões, V Slepushkin, E Pretzer, J J Rossi, Erik De Clercq, V P Antao, M L Collins, M C de Lima | Enhanced inhibition of HIV-1 replicat... | ||
| Paul J Lewi, Marc R De Jonge, Frits F D Daeyaert, Luc Koymans, Maarten H Vinkers, Jan Heeres, Paul A J Janssen, Edward Arnold, Kalyan Das, Art D Clark, Stephen H Hughes, Paul L Boyer, Marie-Pierre P De Béthune, Rudi Pauwels, Koen Andries, Michael Kukla, Donald W Ludovici, Bart De Corte, Robert W Kavash, Chih Y Ho, Paul J Lewis | On the detection of multiple-binding ... | ||
| P Hafkemeyer, K A Neftel, Ulrich Hübscher | HIV-reverse transcriptase and human D... | ||
| Erik De Clercq | Perspectives for the chemotherapy of ... | ||
| Chen Liang, Mark A. Wainberg | The role of Tat in HIV-1 replication:... | ||
| Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari | Structural determinants of HIV-1 reve... | ||
| Maria Letizia Barreca, Laura De Luca, Nunzio Iraci, Angela Rao, Stefania Ferro, Giovanni Maga, Alba Chimirri | Structure-based pharmacophore identif... | ||
| Sherine S L Chan, Janine H Santos, Joel N Meyer, Bhaskar S Mandavilli, Dennis L Cook, Consuelo L McCash, Grace E Kissling, Abraham Nyska, Julie F Foley, Bennett Van Houten, William C Copeland, Vernon E Walker, Kristine L Witt, Jack B Bishop | Mitochondrial toxicity in hearts of C... | ||
| Mark A. Wainberg, S Bour, R Geleziunas, Z Bentwich | [Antiviral strategies in the replicat... | ||
| María-Cruz Bonache, Cristina Chamorro, Sonsoles Velázquez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Ana San-Félix | N-3 substituted TSAO derivatives as a... | ||
| G T Tan, J M Pezzuto, A D Kinghorn, Stephen H Hughes | Evaluation of natural products as inh... | ||
| Jorge L Martínez-Cajas, Nitika Pant-Pai, Marina B Klein, Mark A. Wainberg | Role of genetic diversity amongst HIV... | ||
| Erik De Clercq, Robert Snoeck | [Current acquisitions in antiviral dr... | ||
| Rudi Pauwels, M P de Bethune, Koen Andries, Paul Stoffels, P Janssen, Erik De Clercq | Discovery, development and characteri... | ||
| Erik De Clercq | Perspectives of non-nucleoside revers... | ||
| N Gashnikova, O Plyasunova, Y Kiseleva, N Fedyuk, A Pokrovsky | In vitro study of resistance-associat... | ||
| Erik De Clercq | Novel compounds in preclinical/early ... | ||
| Erik De Clercq | New developments in anti-HIV chemothe... | ||
| 2013 | John E Tavis, Xiaohong Cheng, Yuan Hu, Michael Totten, Feng Cao, Eleftherios Michailidis, Rajeev Aurora, Marvin J Meyers, E Jon Jacobsen, Michael A. Parniak, Stefan G Sarafianos | The hepatitis B virus ribonuclease h ... | |
| 2013 | Mikhail S Novikov, Vladimir T Valuev-Elliston, Denis A Babkov, Maria P Paramonova, Alexander V Ivanov, Sergey A Gavryushov, Anastasia L Khandazhinskaya, Sergey N Kochetkov, Christophe Pannecouque, Graciela Andrei, Robert Snoeck, Jan Balzarini, Katherine L Seley-Radtke | N(1),N(3)-disubstituted uracils as no... | |
| 2013 | Dongyue Li, Peng Zhan, Huiqing Liu, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2013 | Daniel G Kuroda, Joseph David Bauman, J Reddy Challa, Disha Patel, Thomas Troxler, Kalyan Das, Edward Arnold, Robin M Hochstrasser | Snapshot of the equilibrium dynamics ... | |
| 2013 | J-H Lee, Atsuko Hachiya, S-K Shin, J Lee, Hiroyuki Gatanaga, Shinichi Oka, Karen A Kirby, Yee Tsuey Ong, Stefan G Sarafianos, William R Folk, Wangdon Yoo, Sun Pyo Hong, S-O Kim | Restriction fragment mass polymorphis... | |
| 2013 | Kalyan Das, Edward Arnold | HIV-1 reverse transcriptase and antiv... | |
| 2013 | Kalyan Das, Edward Arnold | HIV-1 reverse transcriptase and antiv... | |
| 2013 | Hong-Tao Xu, Susan P Colby-Germinario, Eugene L Asahchop, Maureen Oliveira, Matthew McCallum, Susan M Schader, Yingshan Han, Yudong Quan, Stefan G Sarafianos, Mark A. Wainberg | The Effect of Mutations at Position E... | |
| 2013 | Xuwang Chen, Yuanyuan Li, Shufang Ding, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Huiqing Liu, Xinyong Liu | Discovery of Piperidine-Linked Pyridi... | |
| 2013 | Ravindra K Gupta, DA Van de Vijver, S Manicklal, MA Wainberg | Evolving uses of oral reverse transcr... | |
| 2013 | Mariela Bollini, Kathleen M Frey, José A Cisneros, Krasimir A Spasov, Kalyan Das, Joseph David Bauman, Edward Arnold, Karen S Anderson, William L Jorgensen | Extension into the entrance channel o... | |
| 2013 | A Heredia, CE Davis, MS Reitz, NM Le, MA Wainberg, JS Foulke, LX Wang, RR Redfield | Targeting of the Purine Biosynthesis ... | |
| 2013 | Jan Balzarini, Graciela Andrei, Emanuela Balestra, Dana Huskens, Christophe Vanpouille, Andrea Introini, Sonia Zicari, Sandra Liekens, Robert Snoeck, Antonín Holý, CF Perno, Leonid Margolis, Dominique Schols | A Multi-targeted Drug Candidate with ... | |
| 2013 | Ye Tian, Diwakar Rai, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Huiqing Liu, Xinyong Liu | Design, Synthesis, and Biological Eva... | |
| 2013 | Hai-Qiu Wu, Zi-Hong Yan, Wen-Xue Chen, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Dirk Daelemans, Christophe Pannecouque | Towards new C6-rigid S-DABO HIV-1 rev... | |
| 2013 | Matthew McCallum, Maureen Oliveira, Ruxandra-Ilinca Ibanescu, Victor G Kramer, Daniela D Moisi, Eugene L Asahchop, Bluma G Brenner, Richard Harrigan, Hongtao Xu, Mark A. Wainberg | Basis for the Early and Preferential ... | |
| 2013 | Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd | Inhibition of HIV-1 Reverse Transcrip... | |
| 2013 | Karen A Kirby, Eleftherios Michailidis, Tracy L Fetterly, MA Steinbach, Kamalendra Singh, Bruno Marchand, Maxwell D Leslie, Ariel N Hagedorn, Eiichi N Kodama, Victor E Marquez, Stephen H Hughes, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Effects of 4' - and 2-Substitutions o... | |
| 2013 | Venkata Ramana Sirivolu, Sanjeev Kumar V Verneka, Tatiana Ilina, Nataliya S Myshakina, Michael A. Parniak, Zhengqiang Wang | Clicking 3'-azidothymidine into novel... | |
| 2013 | Erik De Clercq | The Nucleoside Reverse Transcriptase ... | |
| 2013 | Linda L Dunn, Paul L Boyer, Patrick K Clark, Stephen H Hughes | Mutations in HIV-1 reverse transcript... | |
| 2013 | Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno Marchand, Maxwell D Leslie, Andrew D Huber, Yee Tsuey Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Hypersusceptibility mechanism of Teno... | |
| 2013 | Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Rita S Schildknecht, Hongtao Xu, Simani Gaseitswe, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg | The preferential selection of K65R in... | |
| 2013 | R S K Vijayan, Edward Arnold, Kalyan Das | Molecular dynamics study of HIV-1 RT-... | |
| 2013 | Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Xinyong Liu | Novel piperidinylamino-diarylpyrimidi... | |
| 2013 | Joseph David Bauman, Disha Patel, Chhaya Dharia, Marc Fromer, Sameer Ahmed, Yulia Volovik Frenkel, J Thomas Eck, William C Ho, Kalyan Das, Aaron J Shatkin, Edward Arnold | Detecting allosteric sites of HIV-1 r... | |
| 2013 | Shiqiong Yang, Christophe Pannecouque, Dirk Daelemans, Xiao-Dong Ma, Yang Liu, Fen-Er Chen, Erik De Clercq | Molecular design, synthesis and biolo... | |
| 2012 | Christal D Sohl, Rajesh Kasiviswanathan, Jiae Kim, Ugo Pradere, Raymond F Schinazi, William C Copeland, Hiroyuki Mitsuya, Masanori Baba, Karen S Anderson | Balancing Antiviral Potency and Host ... | |
| 2012 | Barry C Johnson, Gary T Pauly, Ganesha Rai, Disha Patel, Joseph David Bauman, Heather L Baker, Kalyan Das, Joel P Schneider, David J Maloney, Edward Arnold, Craig J Thomas, Stephen H Hughes | A comparison of the ability of rilpiv... | |
| 2012 | Martin T Christen, Lakshmi Menon, Nataliya S Myshakina, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima | Structural basis of the allosteric in... | |
| 2012 | Victor G Kramer, Susan M Schader, Maureen Oliveira, Susan P Colby-Germinario, Daniel A Donahue, Diane N Singhroy, Randy Tressler, Richard D Sloan, Mark A. Wainberg | Maraviroc and other HIV-1 entry inhib... | |
| 2012 | Kalyan Das, Sergio E Martinez, Joseph David Bauman, Edward Arnold | HIV-1 reverse transcriptase complex w... | |
| 2012 | Karen A Kirby, Bruno Marchand, Yee Tsuey Ong, Tanyaradzwa P Ndongwe, Atsuko Hachiya, Eleftherios Michailidis, Maxwell D Leslie, Daniel V Sietsema, Tracy L Fetterly, Christopher A Dorst, Kamalendra Singh, Zhengqiang Wang, Michael A. Parniak, Stefan G Sarafianos | Structural and Inhibition Studies of ... | |
| 2012 | Peng Zhan, Xincang Li, Zhongjie Li, Xuwang Chen, Ye Tian, Wenmin Chen, Xinyong Liu, Christophe Pannecouque, Erik De Clercq | Structure-based bioisosterism design,... | |
| 2012 | Xuwang Chen, Peng Zhan, Xin Liu, Ziheng Cheng, Caicai Meng, Siyuan Shao, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Design, synthesis, anti-HIV evaluatio... | |
| 2012 | Atsuko Hachiya, Bruno Marchand, Karen A Kirby, Eleftherios Michailidis, Xiongying Tu, Krzysztof Palczewski, Yee Tsuey Ong, Zhongjie Li, Daniel T Griffin, Matthew M Schuckmann, Junko Tanuma, Shinichi Oka, Kamalendra Singh, Eiichi N Kodama, Stefan G Sarafianos | HIV-1 reverse transcriptase (RT) poly... | |
| 2012 | Tatiana Ilina, Krystal Labarge, Stefan G Sarafianos, Rieko Ishima, Michael A. Parniak | Inhibitors of HIV-1 Reverse Transcrip... | |
| 2012 | Ye Tian, Peng Zhan, Diwakar Rai, Jiyan Zhang, Erik De Clercq, Xinyong Liu | Recent advances in the research of 2,... | |
| 2012 | Eleftherios Michailidis, Kamlendra Singh, Emily M Ryan, Atsuko Hachiya, Yee Tsuey Ong, Karen A Kirby, Bruno Marchand, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | Effect of translocation defective rev... | |
| 2012 | Sergio R Ribone, Volker Leen, Marcela Madrid, Wim Dehaen, Dirk Daelemans, Christophe Pannecouque, Margarita C Briñón | Synthesis, biological evaluation and ... | |
| 2012 | Shiqiong Yang, Fen-Er Chen, Erik De Clercq | Dihydro-alkoxyl-benzyl-oxopyrimidine ... | |
| 2012 | Dongyue Li, Peng Zhan, Erik De Clercq, Xinyong Liu | Strategies for the design of HIV-1 no... | |
| 2012 | Wenwen Chen, Peng Zhan, Erik De Clercq, Xinyong Liu | Recent progress in small molecule CCR... | |
| 2012 | Zhongjie Li, Yuan Cao, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Arylazolylthioacetanilide. Part 11: D... | |
| 2012 | Shuang-Xi Gu, Zhi-Ming Li, Xiao-Dong Ma, Shi-Qiong Yang, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Chiral resolution, absolute configura... | |
| 2012 | Eva-María Priego, Anna Karlsson, Federico Gago, María-José Camarasa, Jan Balzarini, María-Jesús Pérez-Pérez | Recent advances in thymidine kinase 2... | |
| 2012 | Xuwang Chen, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2012 | Christophe Vanpouille, Andrea Lisco, Andrea Introini, Jean-Charles Grivel, Arshi Munawwar, Melanie Merbah, Raymond F Schinazi, Marco Derudas, Christopher McGuigan, Jan Balzarini, Leonid Margolis | Exploiting the anti-HIV-1 activity of... | |
| 2012 | Peng Zhan, Wenmin Chen, Zhongjie Li, Xincang Li, Xuwang Chen, Ye Tian, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Discovery of novel 2-(3-(2-chlorophen... | |
| 2012 | Xincang Li, Peng Zhan, Erik De Clercq, Xinyong Liu | The HIV-1 Non-Nucleoside Reverse Tran... | |
| 2012 | K O François, Jan Balzarini | Potential of carbohydrate-binding age... | |
| 2012 | Kamalendra Singh, Bruno Marchand, Devendra K Rai, Bechan Sharma, Eleftherios Michailidis, Emily M Ryan, Kayla B Matzek, Maxwell D Leslie, Ariel N Hagedorn, Zhongjie Li, Pieter R Norden, Atsuko Hachiya, Michael A. Parniak, Hong-Tao Xu, Mark A. Wainberg, Stefan G Sarafianos | Biochemical Mechanism of HIV-1 Resist... | |
| 2012 | Wei-Shau Hu, Stephen H Hughes | HIV-1 Reverse Transcription. | |
| 2012 | Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd | DNA Polymerase β Gap-filling Transles... | |
| 2012 | Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valeria Famiglini, Sandro Cosconati, Giovanni Maga, Alberta Samuele, Emmanuel Gonzales, B Clotet, Dominique Schols, Jose Este, Ettore Novellino, Romano Silvestri | New Nitrogen Containing Substituents ... | |
| 2012 | Changfu Yang, Shuyuan Liu, Taisong Zhang, Yaping Hou, Xiaoli Liu, Yun Gao, Guang Yang, Zhen Wang, Huayun Chen, Ming Li, Zhenyu Zhu | Transmitted antiretroviral drug resis... | |
| 2012 | Paul L Boyer, Patrick K Clark, Stephen H Hughes | HIV-1 and HIV-2 Reverse Transcriptase... | |
| 2012 | Dante Rotili, Alberta Samuele, Domenico Tarantino, Rino Ragno, Ira Musmuca, Flavio Ballante, Giorgia Botta, Ludovica Morera, Marco Pierini, Roberto Cirilli, Maxim B Nawrozkij, Emmanuel Gonzalez, B Clotet, Marino Artico, José A Esté, Giovanni Maga, Antonello Mai | 2-(Alkyl/Aryl)Amino-6-Benzylpyrimidin... | |
| 2012 | Marco Radi, Mafalda Pagano, Luigi Franchi, Daniele Castagnolo, Silvia Schenone, Gianni Casaluce, Claudio Zamperini, Elena Dreassi, Giovanni Maga, Alberta Samuele, Encarna Gonzalo, B Clotet, José A Esté, Maurizio Botta | Synthesis, Biological Activity, and A... | |
| 2012 | Serdal Kirmizialtin, Virginia Nguyen, Kenneth A Johnson, Ron Elber | How conformational dynamics of DNA po... | |
| 2011 | Dimitrios Coutsinos, Cédric F Invernizzi, Daniela D Moisi, Maureen Oliveira, Jorge L Martinez-Cajas, Bluma G Brenner, Mark A. Wainberg | A template-dependent dislocation mech... | |
| 2011 | Mark A. Wainberg, Daniela D Moisi, Maureen Oliveira, Thomas D'Aquin Toni, Bluma G Brenner | Transmission dynamics of the M184V dr... | |
| 2011 | Hong-Tao Xu, Eugene L Asahchop, Maureen Oliveira, Peter K Quashie, Yudong Quan, Bluma G Brenner, Mark A. Wainberg | Compensation by the E138K mutation in... | |
| 2011 | Kalyan Das, Joseph David Bauman, Angela S Rim, Chhaya Dharia, Arthur D Clark, María-José Camarasa, Jan Balzarini, Edward Arnold | Crystal structure of tert-butyldimeth... | |
| 2011 | Matthias Götte | Initiation of HIV reverse transcripti... | |
| 2011 | Anick Auger, Greg L Beilhartz, Siqi Zhu, Elizabeth Cauchon, Jean-Pierre Falgueyret, Jay A Grobler, Maryam Ehteshami, Matthias Götte, Roman A Melnyk | Impact of primer-induced conformation... | |
| 2011 | Chandravanu Dash, Yousef Ahmadibeni, Michael J Hanley, Jui Pandhare, Mathias Gotte, Stuart F J Le Grice, Keykavous Parang | Inhibition of multi-drug resistant HI... | |
| 2011 | Brian J Scarth, Kirsten L White, James M Chen, Eric B Lansdon, S Swaminathan, Michael D Miller, Matthias Götte | Mechanism of resistance to GS-9148 co... | |
| 2011 | Brian J Scarth, Suzanne McCormick, Matthias Götte | Effects of mutations F61A and A62V in... | |
| 2011 | O Jegede, A Khodyakova, M Chernov, J Weber, L Menéndez-Arias, A Gudkov, ME Quiñones-Mateu | Identification of low-molecular weigh... | |
| 2011 | Erik De Clercq | A 40-year journey in search of select... | |
| 2011 | Xuwang Chen, Peng Zhan, Dongyue Li, Erik De Clercq, Xinyong Liu | Recent advances in DAPYs and related ... | |
| 2011 | Mingyan Yu, Zhongjie Li, Shuai Liu, Erkang Fan, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2011 | Peng Zhan, Xuwang Chen, Dongyue Li, Zengjun Fang, Erik De Clercq, Xinyong Liu | HIV-1 NNRTIs: Structural diversity, p... | |
| 2011 | Jing Zhang, Peng Zhan, Jingde Wu, Zhongjie Li, Yan Jiang, Weiying Ge, Christophe Pannecouque, Erik De Clercq, Xinyong Liu | Synthesis and biological evaluation o... | |
| 2011 | Claudette S Satchell, Jane A O'Halloran, Aoife G Cotter, Aaron J Peace, Eileen F O'Connor, Anthony F Tedesco, Eoin R Feeney, John S Lambert, Gerard J Sheehan, Dermot Kenny, Patrick W G Mallon | Increased Platelet Reactivity in HIV-... | |
| 2011 | Allison K Delong, Mingham Wu, Diane Bennett, Neil Parkin, Zhijin Wu, Joseph W Hogan, Rami Kantor | Sequence Quality Analysis Tool (SQUAT... | |
| 2011 | Brian D Herman, Raymond F Schinazi, Hong-Wang Zhang, James H Nettles, Richard Stanton, Mervi Detorio, Aleksandr Obikhod, Ugo Pradère, Steven J Coats, John W Mellors, Nicolas Sluis-Cremer | Substrate mimicry: HIV-1 reverse tran... | |
| 2011 | Jing-Rong Ye, Lei Guo, Hong-Yan Lu, Ruo-Lei Xin, Yi Zeng | [Genotypic resistance mutations to an... | |
| 2011 | María-Cruz Bonache, Alessandra Cordeiro, Ernesto Quesada, Els Vanstreels, Dirk Daelemans, María-José Camarasa, Jan Balzarini, Ana San-Félix | Selective inhibition of Human Immunod... | |
| 2011 | Mikhail S Novikov, Olga N Ivanova, Alexander V Ivanov, Alexander A Ozerov, Vladimir T Valuev-Elliston, Kartik Temburnikar, Galina V Gurskaya, Sergey N Kochetkov, Christophe Pannecouque, Jan Balzarini, Katherine L Seley-Radtke | 1-[2-(2-Benzoyl- and 2-benzylphenoxy)... | |
| 2011 | Xiao-Dong Ma, Shi-Qiong Yang, Shuang-Xi Gu, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV activity of ar... | |
| 2011 | Graciela Andrei, Andrea Lisco, Christophe Vanpouille, Andrea Introini, Emanuela Balestra, Joost van den Oord, Tomas Cihlar, CF Perno, Robert Snoeck, Leonid Margolis, Jan Balzarini | Topical tenofovir, a microbicide effe... | |
| 2011 | Han-Ping Li, Wei Guo, Yong-Jian Liu, Zuo-Yi Bao, Lin Li, Dao-Min Zhuang, Si-Yang Liu, Zhengqiang Wang, Xiao-Lin Wang, Jing-Yun Li | [Screening program on novel drug resi... | |
| 2011 | Tao Dong, Yongqing Zhang, Ke Yi Xu, Huiping Yan, Ian James, Yanchun Peng, Marie-Eve Blais, Silvana Gaudieri, Xinyue Chen, Wenhui Lun, Hao Wu, Wen Yan Qu, Tim Rostron, Ning Li, Yu Mao, Simon Mallal, Xiaoning Xu, Andrew McMichael, Mina John, Sarah L Rowland-Jones | Extensive HLA-driven viral diversity ... | |
| 2011 | Qingguo Gong, Lakshmi Menon, Tatiana Ilina, Lena G Miller, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima | Interaction of HIV-1 reverse transcri... | |
| 2011 | Matthew W Kellinger, Kenneth A Johnson | Role of induced fit in limiting discr... | |
| 2011 | Zhinan Jin, Jerome Deval, Kenneth A Johnson, David C Swinney | Characterization of the elongation co... | |
| 2011 | Stefania Butini, Sandra Gemma, Margherita Brindisi, Giuseppe Borrelli, Isabella Fiorini, Alberta Samuele, Aristotele Karytinos, Marcella Facchini, Andrea Lossani, Samantha Zanoli, Giuseppe Campiani, Ettore Novellino, Federico Focher, Giovanni Maga | Enantioselective binding of second ge... | |
| 2011 | Dante Rotili, Domenico Tarantino, Marino Artico, Maxim B Nawrozkij, Emmanuel Gonzalez-Ortega, B Clotet, Alberta Samuele, José A Esté, Giovanni Maga, Antonello Mai | Diarylpyrimidine-dihydrobenzyloxopyri... | |
| 2011 | Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valerio Gatti, Giovanni Maga, Alberta Samuele, Christophe Pannecouque, Dominique Schols, Jan Balzarini, Ettore Novellino, Romano Silvestri | Indolylarylsulfones as HIV-1 non-nucl... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | N-3 Hydroxylation of Pyrimidine-2,4-d... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | 6-Benzoyl-3-hydroxypyrimidine-2,4-dio... | |
| 2011 | Jing Tang, Kasthuraiah Maddali, Mathieu Metifiot, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang | 3-Hydroxypyrimidine-2,4-diones as an ... | |
| 2011 | Yuan Yuan, Hui Xing, Xiao-Yu Wang, Chun-hua Liu, Li-Ting Yang, Ben-Feng Zheng, Xia Wang, Yu-Hua Ruan, Zhe Wang, Hong-wei Liu, Yi-ming Shao | [The prevalence of HIV-1 drug resista... | |
| 2011 | Peibin Zeng, Jingxing Wang, Yi Huang, Xiaoming Guo, Jinming Li, Guoxin Wen, Tonghan Yang, Zhongqiao Yun, Miao He, Yu Liu, Yuzhe Yuan, Jane Schulmann, Simone Glynn, Paul Ness, J Brooks Jackson, Hua Shan | The human immunodeficiency virus-1 ge... | |
| 2011 | Alberta Samuele, Sara Bisi, Alexandra Kataropoulou, Giuseppe La Regina, Francesco Piscitelli, Valerio Gatti, Romano Silvestri, Giovanni Maga | Mechanism of interaction of novel ind... | |
| 2011 | Tanyaradzwa P Ndongwe, Adeyemi O Adedeji, Eleftherios Michailidis, Yee Tsuey Ong, Atsuko Hachiya, Bruno Marchand, Emily M Ryan, Devendra K Rai, Karen A Kirby, Angela S Whatley, Donald H Burke, Marc Johnson, Shilei Ding, Yi-Min Zheng, Shan-Lu Liu, Ei-Ichi Kodama, Krista A Delviks-Frankenberry, Vinay K Pathak, Hiroyuki Mitsuya, Michael A. Parniak, Kamalendra Singh, Stefan G Sarafianos | Biochemical, inhibition and inhibitor... | |
| 2011 | Mark A Ditzler, Debojit Bose, Nikolozi Shkriabai, Bruno Marchand, Stefan G Sarafianos, Mamuka Kvaratskhelia, Donald H Burke | Broad-spectrum aptamer inhibitors of ... | |
| 2011 | Karen A Kirby, Kamalendra Singh, Eleftherios Michailidis, Bruno Marchand, Eiichi N Kodama, Noriyuki Ashida, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos | The sugar ring conformation of 4'-eth... | |
| 2011 | Atsuko Hachiya, Eiichi N Kodama, Matthew M Schuckmann, Karen A Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G Sarafianos | K70Q adds high-level tenofovir resist... | |
| 2011 | Joseph David Bauman, Disha Patel, Edward Arnold | Fragment Screening and HIV Therapeutics. | |
| 2011 | Anthony K Felts, Krystal Labarge, Joseph David Bauman, Dishaben V Patel, Daniel M Himmel, Edward Arnold, Michael A. Parniak, Ronald M Levy | Identification of alternative binding... | |
| 2011 | Suhman Chung, Daniel M Himmel, Jian-Kang Jiang, Krzysztof Wojtak, Joseph David Bauman, Jason W Rausch, Jennifer A Wilson, John A Beutler, Craig J Thomas, Edward Arnold, Stuart F J Le Grice | Synthesis, activity, and structural a... | |
| 2011 | Suhman Chung, Jennifer T Miller, Barry C Johnson, Stephen H Hughes, Stuart F J Le Grice | Mutagenesis of the human immunodefici... | |
| 2011 | Eugene L Asahchop, Maureen Oliveira, Mark A. Wainberg, Bluma G Brenner, Daniela D Moisi, Thomas D'Aquin Toni, Cecile L Tremblay | Characterization of the E138K resista... | |
| 2011 | Bluma G Brenner, Matthew Lowe, Daniela D Moisi, Isabelle Hardy, Simon Gagnon, Hugues Charest, Jean Guy Baril, Mark A. Wainberg, Michel Roger | Subtype diversity associated with the... | |
| 2010 | Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Bluma G Brenner, Mark A. Wainberg | Factors affecting template usage in t... | |
| 2010 | Guido van Marle, Deirdre L Church, Kali D Nunweiler, Kris Cannon, Mark A. Wainberg, M John Gill | Higher levels of Zidovudine resistant... | |
| 2010 | Hong-Tao Xu, Maureen Oliveira, Yudong Quan, Tamara Bar-Magen, Mark A. Wainberg | Differential impact of the HIV-1 non-... | |
| 2010 | Wujie Li, Mou Cao, Lu Pei, Xiaomei Ling, Bingchao Li, Zhenjun Yang | Study on steady-state kinetics of nuc... | RT,All properties |
| 2010 | Erik De Clercq | Antiretroviral drugs. | |
| 2010 | John C Martin, Michael J M Hitchcock, Erik De Clercq, William H Prusoff | Early nucleoside reverse transcriptas... | |
| 2010 | Erik De Clercq | In search of a selective therapy of v... | |
| 2010 | Zhao-Sen Zeng, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq | Lead optimization of diarylpyrimidine... | |
| 2010 | Yong-Hong Liang, Qiu-Qin He, Zhao-Sen Zeng, Zhi-Qian Liu, Xiao-Qing Feng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq | Synthesis and anti-HIV activity of 2-... | |
| 2010 | Romuald Corbau, Julie Mori, Chris Phillips, Lesley Fishburn, Alex Martin, Charles Mowbray, Wendy Panton, Caroline Smith-Burchnell, Adele Thornberry, Heather Ringrose, Thorsten Knöchel, Steve Irving, Mike Westby, Anthony Wood, Manos Perros | Lersivirine: a Non-Nucleoside Reverse... | RT,All properties |
| 2010 | Zhao-Sen Zeng, Qiu-Qin He, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Hybrid diarylbenzopyrimidine non-nucl... | |
| 2010 | Alberta Samuele, Emmanuele Crespan, Samanta Vitellaro, Anna-Maria Monforte, Patrizia Logoteta, Alba Chimirri, Giovanni Maga | Slow binding-tight binding interactio... | |
| 2010 | Anna-Maria Monforte, Patrizia Logoteta, Laura De Luca, Nunzio Iraci, Stefania Ferro, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Novel 1,3-dihydro-benzimidazol-2-ones... | |
| 2010 | Matthias Götte, Jason W Rausch, Bruno Marchand, Stefan G Sarafianos, Stuart F J Le Grice | Reverse transcriptase in motion: conf... | |
| 2010 | Viktor von Wyl, Maryam Ehteshami, Jori Symons, Philippe Bürgisser, Monique Nijhuis, Lisa M Demeter, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard | Epidemiological and biological eviden... | |
| 2010 | Greg L Beilhartz, Matthias Götte | HIV-1 Ribonuclease H: Structure, Cata... | |
| 2010 | Yuhua Ruan, Hui Xing, Xia Wang, Heng Tang, Zhengqiang Wang, Hongwei Liu, Bin Su, Jianjun Wu, Hanping Li, Lingjie Liao, Jinming Li, Julia Wei Wu, Yiming Shao | Virologic outcomes of first-line HAAR... | |
| 2010 | Zhengqiang Wang, Jing Tang, Christine E Salomon, Christine D Dreis, Robert Vince | Pharmacophore and structure-activity ... | |
| 2010 | Martin Di Grandi, Matthew Olson, Amar S Prashad, Geraldine Bebernitz, Amara Luckay, Stanley Mullen, Yongbo Hu, Girija Krishnamurthy, Keith Pitts, John O'Connell | Small molecule inhibitors of HIV RT R... | |
| 2010 | Li-Jia Xu, Zong-Gen Peng, Hong-Shan Chen, Jie Wang, Pei-Gen Xiao | Bioactive triterpenoids from Kadsura ... | |
| 2010 | H Nina Kim, Jing Wang, James Hughes, Robert Coombs, Jorge Sanchez, Stewart Reid, Sinead Delany-Moretlwe, Frances Cowan, Jonathan Fuchs, Susan H Eshleman, Leila Khaki, Moira A McMahon, Robert F Siliciano, Anna Wald, Connie Celum | Effect of acyclovir on HIV-1 set poin... | |
| 2010 | Hua-Poo Su, Youwei Yan, G Sridhar Prasad, Robert F Smith, Christopher L Daniels, Pravien D Abeywickrema, John C Reid, H Marie Loughran, Maria Kornienko, Sujata Sharma, Jay A Grobler, Bei Xu, Vinod Sardana, Timothy J Allison, Peter D Williams, Paul L Darke, Daria J Hazuda, Sanjeev Munshi | Structural basis for the inhibition o... | RT,RNase H,All properties |
| 2010 | Mia J Biondi, Greg L Beilhartz, Suzanne McCormick, Matthias Götte | N348I in HIV-1 reverse transcriptase ... | |
| 2010 | Pankaj R Daga, Jinsong Duan, Robert J Doerksen | Computational model of hepatitis B vi... | |
| 2010 | Suhman Chung, Michaela Wendeler, Jason W Rausch, Greg L Beilhartz, Matthias Gotte, Barry R O'Keefe, Alun Bermingham, John A Beutler, Shixin Liu, Xiaowei Zhuang, Stuart F J Le Grice | Structure-activity analysis of vinylo... | |
| 2010 | Guozhi Tang, Denis J Kertesz, Minmin Yang, Xianfeng Lin, Zhengqiang Wang, Wentao Li, Zongxing Qiu, Junli Chen, Jianghua Mei, Li Chen, Taraneh Mirzadegan, Seth F Harris, Armando G Villaseñor, Jennifer Fretland, William L Fitch, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp | Exploration of piperidine-4-yl-aminop... | |
| 2010 | Giovanni Maga, Marco Radi, Marie-Aline Gerard, Maurizio Botta, Eric Ennifar | HIV-1 RT Inhibitors with a Novel Mech... | |
| 2010 | Brian D Herman, Ivan Votruba, Antonin Holy, Nicolas Sluis-Cremer, Jan Balzarini | The acyclic 2,4-diaminopyrimidine nuc... | |
| 2010 | Michael E Abram, Andrea L Ferris, Wei Shao, W Gregory Alvord, Stephen H Hughes | Nature, position, and frequency of mu... | |
| 2010 | Hong-Tao Xu, Yudong Quan, Eugene L Asahchop, Maureen Oliveira, Daniella Moisi, Mark A. Wainberg | Comparative biochemical analysis of r... | |
| 2010 | Daniel A Donahue, Richard D Sloan, Björn D Kuhl, Tamara Bar-Magen, Susan M Schader, Mark A. Wainberg | Stage-dependent inhibition of HIV-1 r... | |
| 2010 | Matthew M Schuckmann, Bruno Marchand, Atsuko Hachiya, Eiichi N Kodama, Karen A Kirby, Kamalendra Singh, Stefan G Sarafianos | The N348I mutation at the connection ... | |
| 2010 | Séverine Freisz, Guillaume Bec, Marco Radi, Philippe Wolff, Emmanuele Crespan, Lucilla Angeli, Philippe Dumas, Giovanni Maga, Maurizio Botta, Eric Ennifar | Crystal Structure of HIV-1 Reverse Tr... | RT,All properties |
| 2010 | Xiongying Tu, Kalyan Das, Qianwei Han, Joseph David Bauman, Arthur D Clark, Xiaorong Hou, Yulia Volovik Frenkel, Barbara L Gaffney, Roger A Jones, Paul L Boyer, Stephen H Hughes, Stefan G Sarafianos, Edward Arnold | Structural basis of HIV-1 resistance ... | |
| 2010 | Matthew W Kellinger, Kenneth A Johnson | Nucleotide-dependent conformational c... | RT,All properties |
| 2010 | Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq | 1,2,3-thiadiazole thioacetanilides. P... | |
| 2010 | Michael L Mitchell, Jong Chan Son, Hongyan Guo, Yun-A Im, Eun Jung Cho, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Doris Graupe, Gerry Rhodes, Gong-Xin He, Romas Geleziunas, Lianhong Xu, Choung U Kim | N1-Alkyl pyrimidinediones as non-nucl... | RT,All properties |
| 2010 | Michael L Mitchell, Jong Chan Son, Ill Young Lee, Chong-Kyo Lee, Hae Soo Kim, Hongyan Guo, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Gene Eisenberg, Romas Geleziunas, Lianhong Xu, Choung U Kim | N1-Heterocyclic pyrimidinediones as n... | RT,All properties |
| 2010 | Eric B Lansdon, Katherine M Brendza, Magdeleine Hung, Ruth Wang, Susmith Mukund, Debi Jin, Gabriel Birkus, Nilima Kutty, Xiaohong Liu | Crystal structures of HIV-1 reverse t... | RT,Associated condition,All properties |
| 2010 | Eric B Lansdon, Dharmaraj Samuel, Leanna Lagpacan, Katherine M Brendza, Kirsten L White, Magdeleine Hung, Xiaohong Liu, Constantine G Boojamra, Richard L Mackman, Tomas Cihlar, Adrian S Ray, Mary E McGrath, S Swaminathan | Visualizing the molecular interaction... | RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Polymerase Catalytic Residue Amino Acids,Residues Involved in Catalysis of RNase H,Incorporation of non-standard nucleotides,All properties |
| 2010 | Denis J Kertesz, Christine Brotherton-Pleiss, Minmin Yang, Zhengqiang Wang, Xianfeng Lin, Zongxing Qiu, Donald R Hirschfeld, Shelley K Gleason, Taraneh Mirzadegan, Pete W Dunten, Seth F Harris, Armando G Villaseñor, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp | Discovery of piperidin-4-yl-aminopyri... | RT,All properties |
| 2010 | Viktor von Wyl, Maryam Ehteshami, Lisa M Demeter, Philippe Bürgisser, Monique Nijhuis, Jori Symons, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard | HIV-1 reverse transcriptase connectio... | |
| 2010 | Michael E Abram, Stefan G Sarafianos, Michael A. Parniak | The mutation T477A in HIV-1 reverse t... | |
| 2009 | Thorsten A Kirschberg, Mini Balakrishnan, Neil H Squires, Tiffany Barnes, Katherine M Brendza, Xiaowu Chen, Eugene J Eisenberg, Weili Jin, Nilima Kutty, Stephanie Leavitt, Albert C Liclican, Qi Liu, Xiaohong Liu, John Mak, Jason K Perry, Michael Wang, William J Watkins, Eric B Lansdon | RNase H active site inhibitors of hum... | |
| 2009 | Egor P Tchesnokov, Aleksandr Obikhod, Ivana Massud, Andrea Lisco, Christophe Vanpouille, Beda Brichacek, Jan Balzarini, Christopher McGuigan, Marco Derudas, Leonid Margolis, Raymond F Schinazi, Matthias Götte | Mechanisms associated with HIV-1 resi... | |
| 2009 | Paul L Boyer, B Christie Vu, Zandrea Ambrose, John G Julias, Svenja Warnecke, Chenzhong Liao, Chris Meier, Victor E Marquez, Stephen H Hughes | The nucleoside analogue D-carba T blo... | |
| 2009 | Greg L Beilhartz, Michaela Wendeler, Noel S Baichoo, Jason W Rausch, Stuart F J Le Grice, Matthias Götte | HIV-1 reverse transcriptase can simul... | |
| 2009 | Linda L Dunn, Mary Jane McWilliams, Kalyan Das, Edward Arnold, Stephen H Hughes | Mutations in the thumb allow human im... | |
| 2009 | Kristina A Paris, Omar Haq, Anthony K Felts, Kalyan Das, Edward Arnold, Ronald M Levy | Conformational landscape of the human... | |
| 2009 | Stefan G Sarafianos, Bruno Marchand, Kalyan Das, Daniel M Himmel, Michael A. Parniak, Stephen H Hughes, Edward Arnold | Structure and function of HIV-1 rever... | |
| 2009 | Kazuki Izumi, Eiichi N Kodama, Kazuya Shimura, Yasuko Sakagami, Kentaro Watanabe, Saori Ito, Tsuyoshi Watabe, Yukihiro Terakawa, Hiroki Nishikawa, Stefan G Sarafianos, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka | Design of peptide-based inhibitors fo... | |
| 2009 | Takeshi Naito, Kazuki Izumi, Eiichi N Kodama, Yasuko Sakagami, Keiko Kajiwara, Hiroki Nishikawa, Kentaro Watanabe, Stefan G Sarafianos, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka | SC29EK, a peptide fusion inhibitor wi... | |
| 2009 | Atsuko Hachiya, Kazuki Shimane, Stefan G Sarafianos, Eiichi N Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi, Shinichi Oka | Clinical relevance of substitutions i... | |
| 2009 | Matthew D Cullen, William C Ho, Joseph David Bauman, Kalyan Das, Edward Arnold, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Crystallographic study of a novel sub... | RT,All properties |
| 2009 | Dai-Shi Su, John J Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J Felock, Meiqing Lu, Ming-Tain Lai, Sinoeun Touch, Gregory Moyer, Daniel J Distefano, Jessica A Flynn, Yuexia Liang, Rosa Sanchez, Sridhar Prasad, Youwei Yan, Rebecca A Perlow-Poehnelt, Maricel Torrent, Michael D Miller, Joe P Vacca, Theresa M Williams, Neville J Anthony | Substituted tetrahydroquinolines as p... | RT,All properties |
| 2009 | Young-Sam Lee, W Dexter Kennedy, Y Whitney Yin | Structural insight into processive hu... | |
| 2009 | Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg | Signature nucleotide polymorphisms at... | |
| 2009 | Yudong Quan, Chen Liang, Bluma G Brenner, Mark A. Wainberg | Multidrug-resistant variants of HIV t... | |
| 2009 | Susan P Colby-Germinario, Adan Rios, Jorge Quesada, Dallas Anderson, Allan L Goldstein, Theresa Fossum, Mark A. Wainberg | HIV inactivation by cross-linking of ... | |
| 2009 | Hongtao Xu, Yudong Quan, Bluma G Brenner, Tamara Bar-Magen, Maureen Oliveira, Susan M Schader, Mark A. Wainberg | Human immunodeficiency virus type 1 r... | |
| 2009 | Dan Turner, Eduardo Shahar, Eugene Katchman, Eynat Kedem, Natasha Matus, Michal Katzir, Gamal Hassoun, Shimon Pollack, Rivka Kessner, Mark A. Wainberg, Boaz Avidor | Prevalence of the K65R resistance rev... | |
| 2009 | Daniel M Himmel, Karen A Maegley, Tom A Pauly, Joseph David Bauman, Kalyan Das, Chhaya Dharia, Arthur D Clark, Kevin Ryan, Michael J Hickey, Robert A Love, Stephen H Hughes, Simon Bergqvist, Edward Arnold | Structure of HIV-1 reverse transcript... | RT,RNase H,All properties |
| 2009 | Kalyan Das, Rajiv P Bandwar, Kirsten L White, Joy Y Feng, Stefan G Sarafianos, Steven Tuske, Xiongying Tu, Arthur D Clark, Paul L Boyer, Xiaorong Hou, Barbara L Gaffney, Roger A Jones, Michael D Miller, Stephen H Hughes, Edward Arnold | Structural basis for the role of the ... | RT,All properties |
| 2009 | Hironori Nishitsuji, Takaya Hayashi, Tomosaburo Takahashi, Masashi Miyano, Mari Kannagi, Takao Masuda | Augmentation of reverse transcription... | |
| 2009 | L Menéndez-Arias | Mutation Rates and Intrinsic Fidelity... | Frameshift Error Rate,All properties |
| 2009 | Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Daniela D Moisi, Maureen Oliveira, Bluma G Brenner, Mark A. Wainberg | Template usage is responsible for the... | |
| 2009 | Anders Vahlne | A historical reflection on the discov... | |
| 2009 | Alberta Samuele, Alexandra Kataropoulou, Marco Viola, Samantha Zanoli, Giuseppe La Regina, Francesco Piscitelli, Romano Silvestri, Giovanni Maga | Non-nucleoside HIV-1 reverse transcri... | |
| 2009 | Marco Radi, Giovanni Maga, Maddalena Alongi, Lucilla Angeli, Alberta Samuele, Samantha Zanoli, Luca Bellucci, Andrea Tafi, Gianni Casaluce, Gianluca Giorgi, Mercedes Armand-Ugon, Emmanuel Gonzalez, José A Esté, Mireille Baltzinger, Guillaume Bec, Philippe Dumas, Eric Ennifar, Maurizio Botta | Discovery of chiral cyclopropyl dihyd... | |
| 2009 | MC Puertas, MJ Buzón, A Artese, S Alcaro, L Menéndez-Arias, CF Perno, B Clotet, F Ceccherini-Silberstein, J Martinez-Picado | Effect of the human immunodeficiency ... | |
| 2009 | Stefania Butini, Margherita Brindisi, Sandro Cosconati, Luciana Marinelli, Giuseppe Borrelli, Salvatore Sanna Coccone, Anna Ramunno, Giuseppe Campiani, Ettore Novellino, Samantha Zanoli, Alberta Samuele, Gianluca Giorgi, Alberto Bergamini, Michela Di Mattia, Silvana Lalli, Bruno Galletti, Sandra Gemma, Giovanni Maga | Specific targeting of highly conserve... | |
| 2009 | Francesco Piscitelli, Antonio Coluccia, Andrea Brancale, Giuseppe La Regina, Anna Sansone, Cesare Giordano, Jan Balzarini, Giovanni Maga, Samantha Zanoli, Alberta Samuele, Roberto Cirilli, Francesco La Torre, Antonio Lavecchia, Ettore Novellino, Romano Silvestri | Indolylarylsulfones bearing natural a... | |
| 2009 | Alexandra Kataropoulou, Chiara Bovolenta, Amalia Belfiore, Sonia Trabatti, Anna Garbelli, Simona Porcellini, Rossella Lupo, Giovanni Maga | Mutational analysis of the HIV-1 auxi... | |
| 2009 | Anna-Maria Monforte, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Design, synthesis, and structure-acti... | |
| 2009 | Takuma Kimura, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Eiji Ohashi, Haruo Ohmori, Chikahide Masutani, Fumio Hanaoka, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Penicilliols A and B, novel inhibitor... | |
| 2009 | Yoshiyuki Mizushina, Hirohisa Motoshima, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Ken Hirano, Fumio Sugawara, Hiromi Yoshida | 3-O-methylfunicone, a selective inhib... | |
| 2009 | Bo-Liang Deng, Yaofeng Zhao, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis of alkenyldiarylmethanes (A... | |
| 2009 | Erik De Clercq | Anti-HIV drugs: 25 compounds approved... | |
| 2009 | Dharmesh H Mahajan, Christophe Pannecouque, Erik De Clercq, Kishor H Chikhalia | Synthesis and studies of new 2-(couma... | |
| 2009 | Peng Zhan, Zhongjie Li, Xinyong Liu, Erik De Clercq | Sulfanyltriazole/tetrazoles: a promis... | |
| 2009 | Peng Zhan, Xinyong Liu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Synthesis and anti-HIV activity evalu... | |
| 2009 | Peng Zhan, Xinyong Liu, Zengjun Fang, Christophe Pannecouque, Erik De Clercq | 1,2,3-Selenadiazole thioacetanilides:... | |
| 2009 | Peng Zhan, Xinyong Liu, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Design strategies of novel NNRTIs to ... | |
| 2009 | Erik De Clercq | A new drug combination therapy for tr... | |
| 2009 | Franck Chiappini, Elina Teicher, Raphaël Saffroy, Brigitte Debuire, Daniel Vittecoq, Antoinette Lemoine | Relationship between polymerase gamma... | |
| 2009 | Marco Derudas, Davide Carta, Andrea Brancale, Christophe Vanpouille, Andrea Lisco, Leonid Margolis, Jan Balzarini, Christopher McGuigan | The application of phosphoramidate pr... | |
| 2009 | Yong-Hong Liang, Xiao-Qing Feng, Zhao-Sen Zeng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq | Design, synthesis, and SAR of naphthy... | |
| 2009 | Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2009 | Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and in vitro anti-HIV evalu... | |
| 2009 | Xuexiang Zhang, Xueyan Jiang, Hongzhou Lu, Fang Shen, Jiangrong Wang | Dyslipidaemia and Intima-Media Thickn... | |
| 2009 | Peng Zhan, Xinyong Liu, Junjie Zhu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq | Synthesis and biological evaluation o... | |
| 2008 | Thomas J Tucker, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, John C Reid, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan | Discovery of 3-{5-[(6-amino-1H-pyrazo... | RT,All properties |
| 2008 | Thomas J Tucker, Sandeep Saggar, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan | The design and synthesis of diaryl et... | RT,All properties |
| 2008 | Andrea Lisco, Christophe Vanpouille, Egor P Tchesnokov, Jean-Charles Grivel, Angélique Biancotto, Beda Brichacek, Julie Elliott, Emilie Fromentin, Robin Shattock, Peter Anton, Robert Gorelick, Jan Balzarini, Christopher McGuigan, Marco Derudas, Matthias Götte, Raymond F Schinazi, Leonid Margolis | Acyclovir is activated into a HIV-1 r... | RT,All properties |
| 2008 | Julie Lemay, Priscilla Maidou-Peindara, Reynel Cancio, Eric Ennifar, Gaël Coadou, Giovanni Maga, Jean-Christophe Rain, Richard Benarous, Lang Xia Liu | AKAP149 binds to HIV-1 reverse transc... | |
| 2008 | Zhengqiang Wang, Robert Vince | Design and synthesis of dual inhibito... | |
| 2008 | Zachary K Sweeney, Seth F Harris, Seth F Arora, Hassan Javanbakht, Yingqian Li, Jennifer Fretland, James P Davidson, J Roland Billedeau, Shelley K Gleason, Donald R Hirschfeld, Joshua J Kennedy-Smith, Taraneh Mirzadegan, Ralf Roetz, Mark Smith, Sarah Sperry, Judy M Suh, Jeffrey Wu, Stan Tsing, Armando G Villaseñor, Amber Paul, Guoping Su, Gabrielle M Heilek, Julie Qi Hang, Amy S Zhou, Jesper A Jernelius, Fang-Jie Zhang, Klaus Klumpp | Design of annulated pyrazoles as inhi... | RT,All properties |
| 2008 | Samir Abdurahman, Akos Végvári, Masoud Youssefi, Michael Levi, Stefan Höglund, Elin Andersson, Peter Horal, Bo Svennerholm, Jan Balzarini, Anders Vahlne | Activity of the small modified amino ... | |
| 2008 | Thorsten A Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty, Albert C Liclican, Damian J McColl, Neil H Squires, Eric B Lansdon | Triazole derivatives as non-nucleosid... | RT,All properties |
| 2008 | Chandravanu Dash, Brian J Scarth, Christopher Badorrek, Matthias Götte, Stuart F J Le Grice | Examining the ribonuclease H primer g... | |
| 2008 | Chong Fang, Joseph David Bauman, Kalyan Das, Amanda Remorino, Edward Arnold, Robin M Hochstrasser | Two-dimensional infrared spectra reve... | |
| 2008 | Fang Yu, Xinyong Liu, Peng Zhan, Erik De Clercq | Recent advances in the research of HI... | |
| 2008 | Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and biological evaluation o... | |
| 2008 | Yueping Wang, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse-transcri... | |
| 2008 | Patrick P Lestienne, François Boudsocq, Jacques E Bonnet | Initiation of DNA replication by a th... | |
| 2008 | Guangwei Yang, Jianhong Wang, Yao Cheng, Ginger E Dutschman, Hiromichi Tanaka, Masanori Baba, Yung-Chi Cheng | Mechanism of inhibition of human immu... | |
| 2008 | Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2008 | Maryam Ehteshami, Brian J Scarth, Egor P Tchesnokov, Chandravanu Dash, Stuart F J Le Grice, Sabine Hallenberger, Dirk Jochmans, Matthias Götte | Mutations M184V and Y115F in HIV-1 re... | |
| 2008 | Bluma G Brenner, Michel Roger, Daniela D Moisi, Maureen Oliveira, Isabelle Hardy, Reuven Turgel, Hugues Charest, Jean-Pierre Routy, Mark A. Wainberg | Transmission networks of drug resista... | |
| 2008 | Maryam Ehteshami, Greg L Beilhartz, Brian J Scarth, Egor P Tchesnokov, Suzanne McCormick, Brian Wynhoven, P Richard Harrigan, Matthias Götte | Connection domain mutations N348I and... | |
| 2008 | Atsuko Hachiya, Eiichi N Kodama, Stefan G Sarafianos, Matthew M Schuckmann, Yasuko Sakagami, Masao Matsuoka, Masafumi Takiguchi, Hiroyuki Gatanaga, Shinichi Oka | Amino acid mutation N348I in the conn... | |
| 2008 | Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Marco Ponassi, Torsten Unge, Martino Bolognesi | Crystal structures of HIV-1 reverse t... | RT,All properties |
| 2008 | Mitsuki Naganuma, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | 1-deoxyrubralactone, a novel specific... | |
| 2008 | Takuma Kimura, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Novel azaphilones, kasanosins A and B... | |
| 2008 | Krista A Delviks-Frankenberry, Galina N Nikolenko, Paul L Boyer, Stephen H Hughes, John M Coffin, Abhay Jere, Vinay K Pathak | HIV-1 reverse transcriptase connectio... | |
| 2008 | Peng Zhan, Xinyong Liu, Yuan Cao, Yan Wang, Christophe Pannecouque, Erik De Clercq | 1,2,3-Thiadiazole thioacetanilides as... | |
| 2008 | Atsushi Kawamoto, Eiichi N Kodama, Stefan G Sarafianos, Yasuko Sakagami, Satoru Kohgo, Kenji Kitano, Noriyuki Ashida, Yuko Iwai, Hiroyuki Hayakawa, Hirotomo Nakata, Hiroyuki Mitsuya, Edward Arnold, Masao Matsuoka | 2'-deoxy-4'-C-ethynyl-2-halo-adenosin... | |
| 2008 | Jingshan Ren, Phillip P Chamberlain, Anna Stamp, Steven A Short, Kurt L Weaver, Karen R Romines, Richard J Hazen, Andrew Freeman, Robert G Ferris, C Webster Andrews, Lawrence R Boone, Joseph H Chan, David K Stammers | Structural basis for the improved dru... | RT,All properties |
| 2008 | Yongcheng Song, Julian M W Chan, Zev Tovian, Aaron Secrest, Eva Nagy, Kilannin Krysiak, Kyle Bergan, Michael A. Parniak, Eric Oldfield | Bisphosphonate inhibitors of ATP-medi... | |
| 2008 | Scott J Garforth, Michael A. Parniak, Vinayaka R Prasad | Utilization of a deoxynucleoside diph... | |
| 2008 | Tatiana Ilina, Michael A. Parniak | Inhibitors of HIV-1 reverse transcrip... | |
| 2008 | Kalyan Das, Joseph David Bauman, Arthur D Clark, Yulia Volovik Frenkel, Paul J Lewi, Aaron J Shatkin, Stephen H Hughes, Edward Arnold | High-resolution structures of HIV-1 r... | RT,All properties |
| 2008 | Michel L Ntemgwa, Thomas D'Aquin Toni, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Maureen Oliveira, Mark A. Wainberg | Near full-length genomic analysis of ... | |
| 2008 | Joseph David Bauman, Kalyan Das, William C Ho, Mukta Baweja, Daniel M Himmel, Arthur D Clark, Deena A Oren, Paul L Boyer, Stephen H Hughes, Aaron J Shatkin, Edward Arnold | Crystal engineering of HIV-1 reverse ... | RT,All properties |
| 2008 | Jiaping Lai, Jun Wang, Zongwei Cai | Nucleoside reverse transcriptase inhi... | |
| 2008 | Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte | Delayed chain termination protects th... | |
| 2008 | Lu Gao, Mark Nils Hanson, Mini Balakrishnan, Paul L Boyer, Bernard P Roques, Stephen H Hughes, Baek Kim, Robert A Bambara | Apparent defects in processive DNA sy... | |
| 2008 | Michaela Wendeler, Hsiu-Fang Lee, Alun Bermingham, Jennifer T Miller, Oleg Chertov, Marion K Bona, Noel S Baichoo, Maryam Ehteshami, John A Beutler, Barry R O'Keefe, Matthias Götte, Mamuka Kvaratskhelia, Stuart F J Le Grice | Vinylogous ureas as a novel class of ... | |
| 2008 | Jangsuk Oh, Mary Jane McWilliams, John G Julias, Stephen H Hughes | Mutations in the U5 region adjacent t... | |
| 2008 | Zhengqiang Wang, Robert Vince | Synthesis of pyrimidine and quinolone... | |
| 2008 | Bechan Sharma, Emmanuele Crespan, Giuseppe Villani, Giovanni Maga | The balance between the rates of inco... | |
| 2008 | Maryam Ehteshami, Matthias Götte | Effects of mutations in the connectio... | |
| 2008 | Marco Radi, Chiara Falciani, Lorenzo Contemori, Elena Petricci, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Montserrat Terrazas, Marinunzia Castria, Andrea Togninelli, José A Esté, Imma Clotet-Codina, Mercedes Armand-Ugón, Maurizio Botta | A multidisciplinary approach for the ... | |
| 2008 | Alberta Samuele, Marcella Facchini, Dante Rotili, Antonello Mai, Marino Artico, Mercedes Armand-Ugón, José A Esté, Giovanni Maga | Substrate-induced stable enzyme-inhib... | |
| 2008 | Samantha Zanoli, Sandra Gemma, Stefania Butini, Margherita Brindisi, Bhupendra P Joshi, Giuseppe Campiani, Caterina Fattorusso, Marco Persico, Emmanuele Crespan, Reynel Cancio, Silvio Spadari, Ulrich Hübscher, Giovanni Maga | Selective targeting of the HIV-1 reve... | |
| 2008 | Anna-Maria Monforte, Angela Rao, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Maria Letizia Barreca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri | Novel N1-substituted 1,3-dihydro-2H-b... | |
| 2008 | Zachary K Sweeney, James P Dunn, Yingqian Li, Gabrielle M Heilek, Pete W Dunten, Todd R Elworthy, Xiaochun Han, Seth F Harris, Donald R Hirschfeld, J Heather Hogg, Walter Huber, Ann C Kaiser, Denis J Kertesz, Woongki Kim, Taraneh Mirzadegan, Michael G Roepel, Y David Saito, Tania M P C Silva, Steven Swallow, Jahari L Tracy, Armando Villasenor, Harit Vora, Amy S Zhou, Klaus Klumpp | Discovery and optimization of pyridaz... | RT,All properties |
| 2008 | Roger G Ptak, Philippe A Gallay, Dirk Jochmans, Andrew P Halestrap, Urs T Ruegg, Luke A Pallansch, Michael D Bobardt, Marie-Pierre P De Béthune, Johan Neyts, Erik De Clercq, Jean-Maurice Dumont, Pietro Scalfaro, Kamel Besseghir, Roland M Wenger, Brigitte Rosenwirth | Inhibition of human immunodeficiency ... | |
| 2008 | Matthew D Cullen, York-Fong Cheung, Miles D Houslay, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Investigation of the alkenyldiarylmet... | |
| 2008 | Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Design and synthesis of 2-(2,6-dibrom... | |
| 2008 | Ravindra K Rawal, Rajkamal Tripathi, Smitha Kulkarni, R Paranjape, S B Katti, Christophe Pannecouque, Erik De Clercq | 2-(2,6-Dihalo-phenyl)-3-heteroaryl-2-... | |
| 2008 | Erik De Clercq | Emerging antiviral drugs. | |
| 2008 | Zhijian Zhao, Scott E Wolkenberg, Philip E J Sanderson, Meiqing Lu, Vandna Munshi, Gregory Moyer, Meizhen Feng, Anthony V Carella, Linda T Ecto, Lori J Gabryelski, Ming-Tain Lai, Sridar G Prasad, Youwei Yan, Georgia B McGaughey, Michael D Miller, Craig W Lindsley, George D Hartman, Joseph P Vacca, Theresa M Williams | Novel indole-3-sulfonamides as potent... | RT,All properties |
| 2007 | Jingde Wu, Xinyong Liu, Xianchao Cheng, Yuan Cao, Defeng Wang, Zhongjie Li, Wenfang Xu, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq | Synthesis of novel derivatives of 4-a... | |
| 2007 | Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J Low, Peter K Cheung, P Richard Harrigan, Thomas Lengauer, Francisco S Domingues | Structural descriptors of gp120 V3 lo... | |
| 2007 | Hikaru Yamanaka, Hiroyuki Gatanaga, Pope Kosalaraksa, Saori Matsuoka-Aizawa, Tomonori Takahashi, Seisuke Kimura, Shinichi Oka | Novel mutation of human DNA polymeras... | |
| 2007 | Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, David Moore, Benita Yip, Evan Wood, Julio S G Montaner | Continued improvement in survival amo... | |
| 2007 | Tobias Sing, Andrew J Low, Niko Beerenwinkel, Oliver Sander, Peter K Cheung, Francisco S Domingues, Joachim Büch, Martin Däumer, Rolf Kaiser, Thomas Lengauer, P Richard Harrigan | Predicting HIV coreceptor usage on th... | |
| 2007 | Adrian S Ray, Joy Y Feng, Eisuke Murakami, Chung K Chu, Raymond F Schinazi, Karen S Anderson | Interaction of 2'-deoxyguanosine trip... | |
| 2007 | Jianbin Wang, H X Wang, T B Ng | A peptide with HIV-1 reverse transcri... | |
| 2007 | Wei-Hao Liao, Kuo-Jung Huang, Yu-Fen Chang, Shiu-Mei Wang, Ying-Tzu Tseng, Chien-Cheng Chiang, Jaang-Jiun Wang, Chin-Tien Wang | Incorporation of human immunodeficien... | |
| 2007 | Christian Castro, Eric D Smidansky, Kenneth R Maksimchuk, Jamie J Arnold, Victoria S Korneeva, Matthias Götte, William H Konigsberg, Craig E Cameron | Two proton transfers in the transitio... | |
| 2007 | Jianing Wang, Yunho Jin, Kimberly L Rapp, Raymond F Schinazi, Chung K Chu | D- and L-2',3'-didehydro-2',3'-dideox... | |
| 2007 | Zabrina L Brumme, Chanson J Brumme, Celia K S Chui, Theresa Mo, Brian Wynhoven, Conan K Woods, Bethany M Henrick, Robert S Hogg, Julio S G Montaner, P Richard Harrigan | Effects of human leukocyte antigen cl... | |
| 2007 | Zhengqiang Wang, Eric M Bennett, Daniel J Wilson, Christine E Salomon, Robert Vince | Rationally designed dual inhibitors o... | |
| 2007 | Soo-Huey Yap, Chih-Wei Sheen, Jonathan Fahey, Mark Zanin, David Tyssen, Viviane Dias Lima, Brian Wynhoven, Michael Kuiper, Nicolas Sluis-Cremer, P Richard Harrigan, Gilda Tachedjian | N348I in the connection domain of HIV... | RT,Cloned or native,Tagged,Tag Name,Full length or truncated,Storage requirements,RNase H,All properties |
| 2007 | L W Y Tam, Robert S Hogg, Benita Yip, J S G Montaner, P Richard Harrigan, Chanson J Brumme | Performance of a World Health Organiz... | |
| 2007 | Silvia Bertagnolio, Luis Soto-Ramirez, Richard Pilon, Roberto Rodriguez, Monica Viveros, Luis Fuentes, P Richard Harrigan, Theresa Mo, Don Sutherland, Paul Sandstrom | HIV-1 drug resistance surveillance us... | |
| 2007 | M R Loutfy, J M Raboud, J S G Montaner, T Antoniou, Brian Wynhoven, F Smaill, D Rouleau, J Gill, W Schlech, Zabrina L Brumme, Theresa Mo, K Gough, A Rachlis, P Richard Harrigan, S L Walmsley | Assay of HIV gp41 amino acid sequence... | |
| 2007 | Matthew D Cullen, Bo-Liang Deng, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis and biological evaluation o... | |
| 2007 | Giovanni Maga, Marco Radi, Samantha Zanoli, Fabrizio Manetti, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Chiara Falciani, Montserrat Terrazas, Jaume Vilarrasa, Maurizio Botta | Discovery of non-nucleoside inhibitor... | |
| 2007 | Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna-Maria Monforte, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Alba Chimirri | Discovery of novel benzimidazolones a... | |
| 2007 | Reynel Cancio, Antonello Mai, Dante Rotili, Marino Artico, Gianluca Sbardella, Imma Clotet-Codina, José A Esté, Emmanuele Crespan, Samantha Zanoli, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Slow-, tight-binding HIV-1 reverse tr... | |
| 2007 | Kassim F Adebambo, Samantha Zanoli, Michael G Thomas, Reynel Cancio, Nicola M Howarth, Giovanni Maga | N2-benzyloxycarbonylguan-9-yl acetic ... | |
| 2007 | Stefania Paolucci, Fausto Baldanti, Giulia Campanini, Reynel Cancio, Amalia Belfiore, Giovanni Maga, Giuseppe Gerna | NNRTI-selected mutations at codon 190... | |
| 2007 | Giuseppe La Regina, Antonio Coluccia, Francesco Piscitelli, Alberto Bergamini, Anna Sinistro, Antonella Cavazza, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Ettore Novellino, Marino Artico, Romano Silvestri | Indolyl aryl sulfones as HIV-1 non-nu... | |
| 2007 | Michael G Thomas, Giovanni Maga, Jean-François Mouscadet, Nicola M Howarth | Investigation of novel lipid-function... | |
| 2007 | Guangwei Yang, Ginger E Dutschman, Chuan-Jen Wang, Hiromichi Tanaka, Masanori Baba, Karen S Anderson, Yung-Chi Cheng | Highly selective action of triphospha... | |
| 2007 | Paul L Boyer, John G Julias, Zandrea Ambrose, Maqbool A Siddiqui, Victor E Marquez, Stephen H Hughes | The nucleoside analogs 4'C-methyl thy... | |
| 2007 | Celia K S Chui, Zabrina L Brumme, Chanson J Brumme, Benita Yip, Elizabeth J Phillips, Julio S G Montaner, P Richard Harrigan | A simple screening approach to reduce... | |
| 2007 | Sonia de Castro, Graziela Andrei, Robert Snoeck, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez | Novel non-nucleoside human cytomegalo... | |
| 2007 | Tokumi Maruyama, Yosuke Demizu, Shigetada Kozai, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq | Antiviral activity of 3-(3,5-dimethyl... | |
| 2007 | Bruno Marchand, Kirsten L White, John K Ly, Nicolas A Margot, Ruth Wang, Martin J McDermott, Michael D Miller, Matthias Götte | Effects of the translocation status o... | |
| 2007 | Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh, Eiichi N Kodama, Guangwei Yang, Christopher M Bailey, Satoru Kohgo, Hiroyuki Hayakawa, Masao Matsuoka, Karen S Anderson, Yung-Chi Cheng, Hiroyuki Mitsuya | Activity against human immunodeficien... | |
| 2007 | Matthias Götte | Should we include connection domain m... | |
| 2007 | Naoko Iwata, Hiroaki Yoshida, Minoru Tobiume, Fumiko Ono, Takuya Shimazaki, Tetsutaro Sata, Noriko Nakajima | Simian fetal brain progenitor cells f... | |
| 2007 | J Scott Daniels, Robert Espina, Kevin Cao, Haodan Yuan, Jianrong Lin, Sharon Diamond, Barry Johnson, James Rodgers, Shimoga Prakash, Steve Unger, David Christ, Gerald Miwa, Liang-Shang Gan, Abdul Mutlib | Species-specific, P450- and sulfotran... | |
| 2007 | Lei Ji, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV-1 activity eva... | |
| 2007 | Matthias Götte | Mechanisms of resistance associated w... | |
| 2007 | George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Matthias Gotte, Janice D Pata, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice | Investigating the "steric gate" of hu... | |
| 2007 | Scott J Garforth, Tae Woo Kim, Michael A. Parniak, Eric T Kool, Vinayaka R Prasad | Site-directed mutagenesis in the fing... | |
| 2007 | Lingjie Liao, Hui Xing, Xincang Li, Yuhua Ruan, Yongqing Zhang, Guangming Qin, Yiming Shao | Genotypic analysis of the protease an... | |
| 2007 | Kristel Van Laethem, Christophe Pannecouque, Anne-Mieke Vandamme | Mutations at 65 and 70 within the con... | |
| 2007 | Kalyan Das, Stefan G Sarafianos, Arthur D Clark, Paul L Boyer, Stephen H Hughes, Edward Arnold | Crystal structures of clinically rele... | |
| 2007 | Galina N Nikolenko, Krista A Delviks-Frankenberry, Sarah Palmer, Frank Maldarelli, Matthew J Fivash, John M Coffin, Vinay K Pathak | Mutations in the connection domain of... | |
| 2007 | Marleen C D G Huigen, Loek de Graaf, Dirk Eggink, Rob Schuurman, Viktor Müller, Anna Stamp, David K Stammers, Charles A B Boucher, Monique Nijhuis | Evolution of a novel 5-amino-acid ins... | |
| 2007 | Chanson J Brumme, P Richard Harrigan, Emma C Preston, Winnie W Y Dong, Brian Wynhoven, Carol Murphy, Julio S G Montaner | Transmission of drug-resistant HIV-1 ... | |
| 2007 | Andrew J Low, Winnie W Y Dong, Dennison Chan, Tobias Sing, Ronald Swanstrom, Mark Jensen, Satish Pillai, Benjamin Good, P Richard Harrigan | Current V3 genotyping algorithms are ... | |
| 2007 | Katharina Skrabal, Andrew J Low, Winnie W Y Dong, Tobias Sing, Peter K Cheung, Fabrizio Mammano, P Richard Harrigan | Determining human immunodeficiency vi... | |
| 2007 | Dirk Daelemans, Richard Lu, Erik De Clercq, Alan Engelman | Characterization of a replication-com... | |
| 2007 | Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Synthesis and evaluation of 2-(2,6-di... | |
| 2007 | Erik De Clercq | Anti-HIV drugs. | |
| 2007 | Takeshi Sakamoto, Matthew D Cullen, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman | Synthesis and anti-HIV activity of ne... | |
| 2007 | Ravindra K Rawal, Raj Kamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq | Synthesis and biological evaluation o... | |
| 2007 | Jan Balzarini, Barbara Orzeszko, Jan K Maurin, Andrzej Orzeszko | Synthesis and anti-HIV studies of 2-a... | |
| 2007 | Clara E Cases-González, Sandra Franco, Miguel Angel Martínez, L Menéndez-Arias | Mutational patterns associated with t... | |
| 2007 | Lei Ji, Fen-Er Chen, Bin Xie, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Synthesis and anti-HIV activity evalu... | |
| 2007 | Bruno Marchand, Egor P Tchesnokov, Matthias Götte | The pyrophosphate analogue foscarnet ... | RT,All properties |
| 2007 | Marshall L Morningstar, Thomas Roth, David W Farnsworth, Marilyn B Kroeger Smith, Karen M Watson, Robert W Buckheit, Kalyan Das, Weiming Zhang, Edward Arnold, John G Julias, Stephen H Hughes, Christopher J Michejda | Synthesis, biological activity, and c... | |
| 2007 | P Richard Harrigan, Theresa Mo, Jennifer Hirsch, Zabrina L Brumme, Paula McKenna, Lee Bacheler | A 21-base pair insertion/duplication ... | |
| 2007 | Sanjeewa Dharmasena, Zita Pongracz, Edward Arnold, Stefan G Sarafianos, Michael A. Parniak | 3'-Azido-3'-deoxythymidine-(5')-tetra... | RT,All properties |
| 2007 | Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, Joseph H Chan, Jörg-Peter Kleim, David K Stammers | Relationship of potency and resilienc... | RT,All properties |
| 2007 | Elizabeth J Phillips, Sonia Gutiérrez, Natalie Jahnke, Benita Yip, Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, Julio S G Montaner | Determinants of nevirapine hypersensi... | |
| 2007 | Krista A Delviks-Frankenberry, Galina N Nikolenko, Rebekah Barr, Vinay K Pathak | Mutations in human immunodeficiency v... | |
| 2007 | Qianwei Han, Stefan G Sarafianos, Edward Arnold, Michael A. Parniak, Barbara L Gaffney, Roger A Jones | Synthesis of AZTpSpCX2ppSA and AZTpSp... | |
| 2007 | Paul L Boyer, Carolyn R Stenbak, David Hoberman, Maxine L Linial, Stephen H Hughes | In vitro fidelity of the prototype pr... | Full length or truncated,Frameshift Error Rate,Nucleotide Substitution Rate,Overall Error Rate,All properties |
| 2007 | Alok Mulky, B Christie Vu, Joan A Conway, Stephen H Hughes, John C Kappes | Analysis of amino acids in the beta7-... | |
| 2007 | Fernando A Frankel, Cédric F Invernizzi, Maureen Oliveira, Mark A. Wainberg | Diminished efficiency of HIV-1 revers... | |
| 2007 | Fernando A Frankel, Dimitrios Coutsinos, Hongtao Xu, Mark A. Wainberg | Kinetics of inhibition of HIV type 1 ... | |
| 2007 | Yazan El Safadi, Valérie Vivet-Boudou, Roland Marquet | HIV-1 reverse transcriptase inhibitors. | RT,All properties |
| 2007 | Shinji Kamisuki, Chisato Ishimaru, Kadohiro Onoda, Isoko Kuriyama, Noriko Ida, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina | Nodulisporol and Nodulisporone, novel... | |
| 2007 | Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia K S Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P Richard Harrigan | Evidence of differential HLA class I-... | |
| 2007 | Dirk Eggink, Marleen C D G Huigen, Charles A B Boucher, Matthias Götte, Monique Nijhuis | Insertions in the beta3-beta4 loop of... | |
| 2007 | William C Drosopoulos, Vinayaka R Prasad | The active site residue Valine 867 in... | |
| 2006 | Hiroshi Ohrui, Satoru Kohgo, Hiroyuki Hayakawa, Eiichi N Kodama, Masao Matsuoka, Tomohiro Nakata, Hiroyuki Mitsuya | 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosi... | RT,All properties |
| 2006 | Dirk Jochmans, Jérôme Deval, Bart Kesteleyn, Herwig Van Marck, Eva Bettens, Inky De Baere, Pascale Dehertogh, Tania Ivens, Marcia Van Ginderen, Bertrand Van Schoubroeck, Maryam Ehteshami, Piet Wigerinck, Matthias Götte, Kurt Hertogs | Indolopyridones inhibit human immunod... | RT,All properties |
| 2006 | Matthias Götte | Effects of nucleotides and nucleotide... | RT,All properties |
| 2006 | Jiong Wang, Carrie Dykes, R A Domaoal, Christine E Koval, R A Bambara, Lisa M Demeter | The HIV-1 reverse transcriptase mutan... | |
| 2006 | Zandrea Ambrose, John G Julias, Paul L Boyer, Vineet N Kewalramani, Stephen H Hughes | The level of reverse transcriptase (R... | |
| 2006 | Frank Goebel, Alexy Yakovlev, Anton L Pozniak, Elena Vinogradova, Griet Boogaerts, Richard Hoetelmans, Marie-Pierre P De Béthune, Monika Peeters, Brian Woodfall | Short-term antiviral activity of TMC2... | |
| 2006 | Antonio Lavecchia, Roberta Costi, Marino Artico, Gaetano Miele, Ettore Novellino, Alberto Bergamini, Emmanuele Crespan, Giovanni Maga, Roberto Di Santo | Arylthiopyrrole (AThP) derivatives as... | |
| 2006 | Roberto Di Santo, Roberta Costi, Marino Artico, Gaetano Miele, Antonio Lavecchia, Ettore Novellino, Alberto Bergamini, Reynel Cancio, Giovanni Maga | Arylthiopyrrole (AThP) derivatives as... | |
| 2006 | Daniel M Himmel, Stefan G Sarafianos, Sanjeewa Dharmasena, Mohammed M Hossain, Kessler McCoy-Simandle, Tatiana Ilina, Arthur D Clark, Jennifer L Knight, John G Julias, Patrick K Clark, Karsten Krogh-Jespersen, Ronald M Levy, Stephen H Hughes, Michael A. Parniak, Edward Arnold | HIV-1 reverse transcriptase structure... | RT,RNase H,All properties |
| 2006 | Gabriella De Martino, Giuseppe La Regina, Rino Ragno, Antonio Coluccia, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri | Indolyl aryl sulphones as HIV-1 non-n... | |
| 2006 | Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong | Novel nonnucleoside inhibitors that s... | |
| 2006 | Jingshan Ren, Charles E Nichols, Anna Stamp, Phillip P Chamberlain, Robert G Ferris, Kurt L Weaver, Steven A Short, David K Stammers | Structural insights into mechanisms o... | |
| 2006 | Roberto Di Santo, Roberta Costi, Marino Artico, Rino Ragno, Antonio Lavecchia, Ettore Novellino, Enrico Gavuzzo, Francesco La Torre, Roberto Cirilli, Reynel Cancio, Giovanni Maga | Design, synthesis, biological evaluat... | |
| 2006 | Carlos Cruchaga, Elena Ansó, Ana Rouzaut, Juan J Martínez-Irujo | Selective excision of chain-terminati... | |
| 2006 | Paul L Boyer, Stefan G Sarafianos, Patrick K Clark, Edward Arnold, Stephen H Hughes | Why do HIV-1 and HIV-2 use different ... | |
| 2006 | Monica E Hamburgh, Kenneth A Curr, Melissa Monaghan, Vasudev R Rao, Snehlata Tripathi, Bradley D Preston, Stefan G Sarafianos, Edward Arnold, Thomas Darden, Vinayaka R Prasad | Structural determinants of slippage-m... | |
| 2006 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, Federico Gago | Dimerization inhibitors of HIV-1 reve... | |
| 2006 | Tokumi Maruyama, Shigetada Kozai, Yosuke Demizu, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq | Synthesis and anti-HIV-1 and anti-HCM... | |
| 2006 | Sarit Aviel-Ronen, Chang Qi Zhu, Bradley P Coe, Ni Liu, Spencer K Watson, Wan L Lam, Ming Sound Tsao | Large fragment Bst DNA polymerase for... | |
| 2006 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, María-Cruz Bonache, Sonia de Castro | TSAO derivatives, inhibitors of HIV-1... | |
| 2006 | N Machouf, R Thomas, V K Nguyen, B Trottier, M R Boulassel, Mark A. Wainberg, Jean-Pierre Routy | Effects of drug resistance on viral l... | |
| 2006 | Lei Ji, Fen-Er Chen, Xiao-Qing Feng, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Non-nucleoside HIV-1 reverse transcri... | |
| 2006 | Nicolas Sluis-Cremer, Noureddine Hamamouch, Ana San Félix, Sonsoles Velazquez, Jan Balzarini, María-José Camarasa | Structure-activity relationships of [... | |
| 2006 | Kirsten L White, James M Chen, Joy Y Feng, Nicolas A Margot, John K Ly, Adrian S Ray, Holly L Macarthur, Martin J McDermott, S Swaminathan, Michael D Miller | The K65R reverse transcriptase mutati... | |
| 2006 | Christine E Koval, Carrie Dykes, Jiong Wang, Lisa M Demeter | Relative replication fitness of efavi... | |
| 2006 | Enzo Tramontano | HIV-1 RNase H: recent progress in an ... | |
| 2006 | Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Combining mutations in HIV-1 reverse ... | |
| 2006 | Carrie Dykes, Jiong Wang, Xia Jin, Vicente Planelles, Dong Sung An, Amanda Tallo, Yangxin Huang, Hulin Wu, Lisa M Demeter | Evaluation of a multiple-cycle, recom... | |
| 2006 | Klaus Klumpp, Tara Mirzadegan | Recent progress in the design of smal... | |
| 2006 | Najim A Al-Masoudi, Yaseen A Al-Soud, Aris Kalogerakis, Christophe Pannecouque, Erik De Clercq | Nitroimidazoles, part 2: Synthesis, a... | |
| 2006 | CF Perno, Valentina Svicher, Dominique Schols, Michela Pollicita, Jan Balzarini, Stefano Aquaro | Therapeutic strategies towards HIV-1 ... | |
| 2006 | Bo-Liang Deng, Matthew D Cullen, Zhigang Zhou, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman | Synthesis and anti-HIV activity of ne... | |
| 2006 | Varuni K Jamburuthugoda, Pauline Chugh, Baek Kim | Modification of human immunodeficienc... | |
| 2006 | Valentina Svicher, Tobias Sing, Maria Mercedes Santoro, Federica Forbici, Fátima Rodríguez-Barrios, Ada Bertoli, Niko Beerenwinkel, Maria Concetta Bellocchi, Federigo Gago, Antonella d'Arminio Monforte, Andrea Antinori, Thomas Lengauer, F Ceccherini-Silberstein, CF Perno | Involvement of novel human immunodefi... | |
| 2005 | Scott R Budihas, Inna Gorshkova, Sergei A Gaidamakov, Antony Wamiru, Marion K Bona, Michael A. Parniak, Robert J Crouch, James B McMahon, John A Beutler, Stuart F J Le Grice | Selective inhibition of HIV-1 reverse... | |
| 2005 | Paul A J Janssen, Paul J Lewi, Edward Arnold, Frits F D Daeyaert, Marc R De Jonge, Jan Heeres, Luc Koymans, Maarten H Vinkers, Jérôme Guillemont, Elisabeth Pasquier, Michael Kukla, Don Ludovici, Koen Andries, Marie-Pierre P De Béthune, Rudi Pauwels, Kalyan Das, Arthur D Clark, Yulia Volovik Frenkel, Stephen H Hughes, Bart Medaer, Fons De Knaep, Hilde Bohets, Fred De Clerck, Ann Lampo, Peter Williams, Paul Stoffels | In search of a novel anti-HIV drug: m... | |
| 2005 | Alok Mulky, Stefan G Sarafianos, Yujiang Jia, Edward Arnold, John C Kappes | Identification of amino acid residues... | |
| 2005 | Joël Didierjean, Catherine Isel, Flore Querré, Jean-François Mouscadet, Anne-Marie Aubertin, Jean-Yves Valnot, Serge R Piettre, Roland Marquet | Inhibition of human immunodeficiency ... | |
| 2005 | Fernando A Frankel, Bruno Marchand, Dan Turner, Matthias Götte, Mark A. Wainberg | Impaired rescue of chain-terminated D... | |
| 2005 | Daniel M Himmel, Kalyan Das, Arthur D Clark, Stephen H Hughes, Abdellah Benjahad, Said Oumouch, Jérôme Guillemont, Sophie Coupa, Alain Poncelet, Imre Csoka, Christophe Meyer, Koen Andries, Chi Hung Nguyen, David S Grierson, Edward Arnold | Crystal structures for HIV-1 reverse ... | RT,Associated condition,All properties |
| 2005 | Erik De Clercq | Emerging anti-HIV drugs. | |
| 2005 | Myriam Witvrouw, Valery Fikkert, Anke Hantson, Christophe Pannecouque, Barry R O'keefe, James McMahon, Leonidas Stamatatos, Erik De Clercq, Anders Bolmstedt | Resistance of human immunodeficiency ... | |
| 2005 | Bo-Liang Deng, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman | Synthesis, anti-HIV activity, and met... | |
| 2005 | Michael E Ignatov, Anthony J Berdis, Stuart F J Le Grice, Mary D Barkley | Attenuation of DNA replication by HIV... | |
| 2005 | Rienk E Jeeninga, Barbara Jan, Birgit van der Linden, Henk van den Berg, Ben Berkhout | Construction of a minimal HIV-1 varia... | |
| 2005 | Ronald B Geskus, Laurence Meyer, Jean-Baptiste Hubert, Hanneke Schuitemaker, Ben Berkhout, Christine Rouzioux, Ioannis D Theodorou, Jean-François Delfraissy, Maria Prins, Roel A Coutinho | Causal pathways of the effects of age... | |
| 2005 | Ben Berkhout, Anthony de Ronde, Lia van der Hoek | Aggressive HIV-1? | |
| 2005 | Luis R Miranda, Matthias Götte, Fei Liang, Daniel R Kuritzkes | The L74V mutation in human immunodefi... | |
| 2005 | Nicolas Sluis-Cremer, Dominique Arion, Urvi Parikh, Dianna Koontz, Raymond F Schinazi, John W Mellors, Michael A. Parniak | The 3'-azido group is not the primary... | |
| 2005 | Lia van der Hoek, Nicole Back, Maarten F Jebbink, Anthony de Ronde, Margreet Bakker, Suzanne Jurriaans, Peter Reiss, Neil Parkin, Ben Berkhout | Increased multinucleoside drug resist... | |
| 2005 | Kirsten L White, Nicolas A Margot, John K Ly, James M Chen, Adrian S Ray, Martina Pavelko, Ruth Wang, Martin J McDermott, S Swaminathan, Michael D Miller | A combination of decreased NRTI incor... | |
| 2005 | Darwin J Operario, Holly M Reynolds, Baek Kim | Comparison of DNA polymerase activiti... | Molecular Weight,Overall Error Rate,All properties |
| 2005 | Jan Balzarini, Miguel Stevens, Erik De Clercq, Dominique Schols, Christophe Pannecouque | Pyridine N-oxide derivatives: unusual... | |
| 2005 | Jan Balzarini, Kristel Van Laethem, Sigrid Hatse, Matheus Froeyen, Els Van Damme, Anders Bolmstedt, Willy Peumans, Erik De Clercq, Dominique Schols | Marked depletion of glycosylation sit... | |
| 2005 | Jan Balzarini, Joeri Auwerx, Fátima Rodríguez-Barrios, Allel Chedad, Viktor Farkas, F Ceccherini-Silberstein, Carlos García-Aparicio, Sonsoles Velázquez, Erik De Clercq, CF Perno, María-José Camarasa, Federico Gago | The amino acid Asn136 in HIV-1 revers... | |
| 2005 | Joeri Auwerx, Joke Van Nieuwenhove, Fátima Rodríguez-Barrios, Sonia de Castro, Sonsoles Velázquez, F Ceccherini-Silberstein, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini | The N137 and P140 amino acids in the ... | |
| 2005 | Fátima Rodríguez-Barrios, Jan Balzarini, Federico Gago | The molecular basis of resilience to ... | |
| 2005 | Joeri Auwerx, Fátima Rodríguez-Barrios, F Ceccherini-Silberstein, Ana San-Félix, Sonsoles Velázquez, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini | The role of Thr139 in the human immun... | |
| 2005 | Albert Nguyen Van Nhien, Cyrille Tomassi, Christophe Len, José Luis Marco-Contelles, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Denis Postel | First synthesis and evaluation of the... | |
| 2005 | F Ceccherini-Silberstein, Federico Gago, Maria Mercedes Santoro, Caterina Gori, Valentina Svicher, Fátima Rodríguez-Barrios, Roberta d'Arrigo, Massimo Ciccozzi, Ada Bertoli, Antonella d'Arminio Monforte, Jan Balzarini, Andrea Antinori, CF Perno | High sequence conservation of human i... | |
| 2005 | Guang-Fu Sun, Xu-Xiang Chen, Fen-Er Chen, Yue-Ping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse-transcrip... | |
| 2005 | Guang-Fu Sun, Yun-Yan Kuang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Non-nucleoside HIV reverse transcript... | |
| 2005 | Johan Vingerhoets, Hilde Azijn, Els Fransen, Inky De Baere, Liesbet Smeulders, Dirk Jochmans, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune | TMC125 displays a high genetic barrie... | |
| 2005 | Natalia A Lebedeva, T A Seredina, V N Silnikov, T V Abramova, A S Levina, Svetlana N Khodyreva, Nadejda I Rechkunova, Olga I Lavrik | Analysis of interactions of DNA polym... | |
| 2005 | Hong Zang, Thomas M Harris, F Peter Guengerich | Kinetics of nucleotide incorporation ... | |
| 2005 | Hong Zang, Thomas M Harris, F Peter Guengerich | Kinetics of nucleotide incorporation ... | |
| 2005 | Tongfei Wu, Matheus Froeyen, Veerle Kempeneers, Christophe Pannecouque, Jing Wang, Roger Busson, Erik De Clercq, Piet Herdewijn | Deoxythreosyl phosphonate nucleosides... | |
| 2005 | Cathryn A Shaw-Reid, Bradley Feuston, Vandna Munshi, Krista Getty, Julie Krueger, Daria J Hazuda, Michael A. Parniak, Michael D Miller, Dale Lewis | Dissecting the effects of DNA polymer... | |
| 2005 | Michael E Abram, Michael A. Parniak | Virion instability of human immunodef... | |
| 2005 | Daniel Summerer, Andreas Marx | 4'C-ethynyl-thymidine acts as a chain... | |
| 2005 | Micha Nethe, Ben Berkhout, Antoinette C van der Kuyl | Retroviral superinfection resistance. | |
| 2005 | Caterina Fattorusso, Sandra Gemma, Stefania Butini, Paul Huleatt, Bruno Catalanotti, Marco Persico, Meri De Angelis, Isabella Fiorini, Vito Nacci, Anna Ramunno, Manuela Rodriquez, Giovanni Greco, Ettore Novellino, Alberto Bergamini, Stefano Marini, Massimo Coletta, Giovanni Maga, Silvio Spadari, Giuseppe Campiani | Specific targeting highly conserved r... | |
| 2005 | Emmanuele Crespan, Samantha Zanoli, Anastasiya Khandazhinskaya, Igor V Shevelev, Maxim Jasko, Ludmila Alexandrova, Marina Kukhanova, Giuseppina Blanca, Giuseppe Villani, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Incorporation of non-nucleoside triph... | |
| 2005 | Gabriella De Martino, Giuseppe La Regina, Alessandra Di Pasquali, Rino Ragno, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri | Novel 1-[2-(diarylmethoxy)ethyl]-2-me... | |
| 2005 | Antonello Mai, Marino Artico, Rino Ragno, Gianluca Sbardella, Silvio Massa, Chiara Musiu, Massimo Mura, Flavia Marturana, Alessandra Cadeddu, Giovanni Maga, Paolo La Colla | 5-Alkyl-2-alkylamino-6-(2,6-difluorop... | |
| 2005 | Emmanuele Crespan, Giada A Locatelli, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Drug resistance mutations in the nucl... | |
| 2005 | Hong Li, Zhengqiang Wang, Wei-guo Cui, Yan Liang, Tian-yi Xin, Jinming Li | [Study on adherence and interrelated ... | |
| 2005 | Yaofeng Zhao, Yang Jin, Jing-Houng Wang, Rui-Rui Wang, Liu-Meng Yang, Wen-Hui Lee, Yong-Tang Zheng, Yongqing Zhang | A novel heme-containing protein with ... | |
| 2005 | Junmei Wang, Xinshan Kang, Irwin D Kuntz, Peter A Kollman | Hierarchical database screenings for ... | |
| 2005 | Abdellah Benjahad, Martine Croisy, Claude Monneret, Emile Bisagni, Dominique Mabire, Sophie Coupa, Alain Poncelet, Imre Csoka, Jérôme Guillemont, Christophe Meyer, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Daniel M Himmel, Kalyan Das, Edward Arnold, Chi Hung Nguyen, David S Grierson | 4-Benzyl and 4-benzoyl-3-dimethylamin... | |
| 2005 | Jan Heeres, Marc R De Jonge, Lucien M H Koymans, Frits F D Daeyaert, Maarten H Vinkers, Koen J A Van Aken, Edward Arnold, Kalyan Das, Amuri Kilonda, Georges J Hoornaert, Frans Compernolle, Marek Cegla, Rasha A Azzam, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Paul A J Janssen | Design, synthesis, and SAR of a novel... | |
| 2005 | Kalyan Das, Paul J Lewi, Stephen H Hughes, Edward Arnold | Crystallography and the design of ant... | |
| 2005 | Dan Turner, Bluma G Brenner, Daniela D Moisi, Chen Liang, Mark A. Wainberg | Substitutions in the Reverse Transcri... | |
| 2005 | Ariel Roldan, Otis U Warren, Rodney S Russell, Chen Liang, Mark A. Wainberg | A HIV-1 minimal gag protein is superi... | |
| 2005 | Mark A. Wainberg, James P C Sawyer, Julio S G Montaner, Robert L Murphy, Daniel R Kuritzkes, Francois Raffi | Challenges for the clinical developme... | |
| 2005 | Andrew R Zolopa, Laura C Lazzeroni, Alex Rinehart, Françoise Brun Vezinet, François Clavel, Ann Collier, Brian Conway, Roy M Gulick, Mark Holodniy, CF Perno, Robert W Shafer, Douglas D Richman, Mark A. Wainberg, Daniel R Kuritzkes | Accuracy, precision, and consistency ... | |
| 2005 | Dan Turner, Bluma G Brenner, Daniela Mosis, Chen Liang, Mark A. Wainberg | Substitutions in the reverse transcri... | |
| 2005 | Ariel Fernández, Dan S Tawfik, Ben Berkhout, Rogier W Sanders, Andrzej Kloczkowski, Taner Sen, Bob Jernigan | Protein promiscuity: drug resistance ... | |
| 2005 | Melaku Adal, Workenesh Ayele, Dawit Wolday, Kifle Dagne, Tsehaynesh Messele, Tesfaye Tilahun, Ben Berkhout, Shlomo Mayaan, Georgios Pollakis, Wendelien Dorigo-Zetsma | Evidence of genetic variability of hu... | |
| 2005 | María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez | TSAO derivatives the first non-peptid... | |
| 2005 | Pia S Kivelä, Anneke Krol, Mika O Salminen, Ronald B Geskus, Jukka I Suni, Veli-Jukka Anttila, Kirsi Liitsola, Veera Zetterberg, Frank Miedema, Ben Berkhout, Roel A Coutinho, Matti A Ristola | High plasma HIV load in the CRF01-AE ... | |
| 2004 | Rachelle J Bienstock, Willliam C Copeland | Molecular insights into NRTI inhibiti... | |
| 2004 | Kirsten L White, James M Chen, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Lisa K Naeger, S Swaminathan, Michael D Miller | Molecular mechanisms of tenofovir res... | |
| 2004 | Elena N Peletskaya, Alex A Kogon, Steven Tuske, Edward Arnold, Stephen H Hughes | Nonnucleoside inhibitor binding affec... | RT,Associated condition,All properties |
| 2004 | Maqbool A Siddiqui, Stephen H Hughes, Paul L Boyer, Hiroyuki Mitsuya, Que N Van, Clifford George, Stefan G Sarafinanos, Victor E Marquez | A 4'-C-ethynyl-2',3'-dideoxynucleosid... | |
| 2004 | Myriam Witvrouw, Bénédicte Van Maele, J Vercammen, Anke Hantson, Y Engelborghs, Erik De Clercq, Christophe Pannecouque, Zeger Debyser | Novel inhibitors of HIV-1 integration. | |
| 2004 | Erik De Clercq | Non-nucleoside reverse transcriptase ... | |
| 2004 | Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Marco Petrella, Mark A. Wainberg | Rationale for maintenance of the M184... | |
| 2004 | Peter R Meyer, Anthony J Smith, Suzanne E Matsuura, Walter A Scott | Effects of primer-template sequence o... | |
| 2004 | George R Painter, Merrick R Almond, Shuli Mao, Dennis C Liotta | Biochemical and mechanistic basis for... | RT,Associated condition,All properties |
| 2004 | Lisa F Rezende, Vinayaka R Prasad | Nucleoside-analog resistance mutation... | RT,Associated condition,All properties |
| 2004 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Effects of mutations in the G tract o... | |
| 2004 | Koen Andries, Hilde Azijn, Theo Thielemans, Donald W Ludovici, Michael Kukla, Jan Heeres, Paul A J Janssen, Bart De Corte, Johan Vingerhoets, Rudi Pauwels, Marie-Pierre P De Béthune | TMC125, a novel next-generation nonnu... | RT,Associated condition,All properties |
| 2004 | Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna-Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà | 2-(2,6-Dihalophenyl)-3-(pyrimidin-2-y... | |
| 2004 | Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, David K Stammers | Crystal structures of HIV-1 reverse t... | |
| 2004 | Julie Qi Hang, Surendran Rajendran, Yanli Yang, Yingqian Li, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin, Klaus Klumpp | Activity of the isolated HIV RNase H ... | |
| 2004 | Yanping He, Fener Chen, Xiongjie Yu, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse transcrip... | |
| 2004 | Jeong-Yun Choi, F Peter Guengerich | Analysis of the effect of bulk at N2-... | |
| 2004 | Satoru Kohgo, Kohei Yamada, Kenji Kitano, Yuko Iwai, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui | Design, efficient synthesis, and anti... | |
| 2004 | Bruno Marchand, Matthias Götte | Impact of the translocational equilib... | |
| 2004 | Eisuke Murakami, Adrian S Ray, Raymond F Schinazi, Karen S Anderson | Investigating the effects of stereoch... | |
| 2004 | Michael B Doughty, Karam Aboudehen, Garland Anderson, Ke Li, Bob Moore, Tina Poolson | Side-chain conformational restriction... | |
| 2004 | Paul J Lewi, Edward Arnold, Koen Andries, Hilde Bohets, Herman Borghys, Arthur D Clark, Frits F D Daeyaert, Kalyan Das, Marie-Pierre P De Béthune, Marc R De Jonge, Jan Heeres, Luc Koymans, Jos Leempoels, Jef Peeters, Philip Timmerman, Walter Van den Broeck, Frédéric Vanhoutte, Gerben Van't Klooster, Maarten H Vinkers, Yulia Volovik, Paul A J Janssen | Correlations between factors determin... | |
| 2004 | Giada A Locatelli, Reynel Cancio, Silvio Spadari, Giovanni Maga | HIV-1 reverse transcriptase inhibitor... | |
| 2004 | Stefania Paolucci, Fausto Baldanti, Giovanni Maga, Reynel Cancio, Maurizio Zazzi, Maurizio Zavattoni, Antonella Chiesa, Silvio Spadari, Giuseppe Gerna | Gln145Met/Leu changes in human immuno... | |
| 2004 | Paul L Boyer, Tomozumi Imamichi, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Effects of the Delta67 complex of mut... | |
| 2004 | Joy Y Feng, Eisuke Murakami, Suzana M Zorca, Allison A Johnson, Kenneth A Johnson, Raymond F Schinazi, Phillip A Furman, Karen S Anderson | Relationship between antiviral activi... | |
| 2004 | Matthias Götte | Inhibition of HIV-1 reverse transcrip... | |
| 2004 | King C Chan, Scott R Budihas, Stuart F J Le Grice, Michael A. Parniak, Robert J Crouch, Sergei A Gaidamakov, Haleem J Isaaq, Antony Wamiru, James B McMahon, John A Beutler | A capillary electrophoretic assay for... | |
| 2004 | Elisabetta Bulgheroni, Francesco Croce, Paola Citterio, Ottavia Viganò, Raffaella Visonà, Eugenio Sala, Massimo Galli, Stefano Rusconi | Unusual codon 69 insertions: influenc... | |
| 2004 | Dan Turner, Bluma G Brenner, Mark A. Wainberg | Relationships among various nucleosid... | |
| 2004 | Dan Turner, Bluma G Brenner, Daniela D Moisi, Mervi Detorio, Raymond Cesaire, Takashi Kurimura, Haruyo Mori, Max Essex, Shlomo Maayan, Mark A. Wainberg | Nucleotide and amino acid polymorphis... | |
| 2004 | Jérôme Deval, Jean-Marc Navarro, Boulbaba Selmi, Jérôme Courcambeck, Joëlle Boretto, Philippe Halfon, Sarah Garrido-Urbani, Josephine Sire, Bruno Canard | A loss of viral replicative capacity ... | |
| 2004 | Jérôme Deval, Kirsten L White, Michael D Miller, Neil T Parkin, Jérôme Courcambeck, Philippe Halfon, Boulbaba Selmi, Joëlle Boretto, Bruno Canard | Mechanistic basis for reduced viral a... | |
| 2004 | Debanu Das, Millie M Georgiadis | The crystal structure of the monomeri... | |
| 2004 | Zandrea Ambrose, Valerie Boltz, Sarah Palmer, John M Coffin, Stephen H Hughes, Vineet N Kewalramani | In vitro characterization of a simian... | |
| 2004 | John G Julias, Paul L Boyer, Mary Jane McWilliams, W Gregory Alvord, Stephen H Hughes | Mutations at position 184 of human im... | |
| 2004 | A Michael Sismour, Stefan Lutz, Jeong-Ho Park, Michael J Lutz, Paul L Boyer, Stephen H Hughes, Steven A Benner | PCR amplification of DNA containing n... | |
| 2004 | Alok Mulky, Stefan G Sarafianos, Edward Arnold, Xiaoming Wu, John C Kappes | Subunit-specific analysis of the huma... | |
| 2004 | Stefan G Sarafianos, Kalyan Das, Stephen H Hughes, Edward Arnold | Taking aim at a moving target: design... | |
| 2004 | George A Freeman, C Webster Andrews Iii, Andrew L Hopkins, Gina S Lowell, Lee T Schaller, Jill R Cowan, Stephen S Gonzales, George W Koszalka, Richard J Hazen, Lawrence R Boone, Rob G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, David J Reynolds, John Milton, Jingshan Ren, David I Stuart, David K Stammers, Joseph H Chan | Design of non-nucleoside inhibitors o... | RT,Associated condition,All properties |
| 2004 | Joeri Auwerx, Robert Esnouf, Erik De Clercq, Jan Balzarini | Susceptibility of feline immunodefici... | |
| 2004 | Stefan G Sarafianos, Stephen H Hughes, Edward Arnold | Designing anti-AIDS drugs targeting t... | |
| 2004 | Giada A Locatelli, Giuseppe Campiani, Reynel Cancio, Elena Morelli, Anna Ramunno, Sandra Gemma, Ulrich Hübscher, Silvio Spadari, Giovanni Maga | Effects of drug resistance mutations ... | |
| 2004 | Reynel Cancio, Silvio Spadari, Giovanni Maga | Vif is an auxiliary factor of the HIV... | |
| 2004 | Louise Z Wang, George L Kenyon, Kenneth A Johnson | Novel mechanism of inhibition of HIV-... | |
| 2004 | Andrew L Hopkins, Jingshan Ren, John Milton, Richard J Hazen, Joseph H Chan, David I Stuart, David K Stammers | Design of non-nucleoside inhibitors o... | RT,Associated condition,All properties |
| 2004 | Erik De Clercq | Antiviral drugs in current clinical use. | |
| 2004 | Joeri Auwerx, Miguel Stevens, An R Van Rompay, Louise E Bird, Jingshan Ren, Erik De Clercq, Bo Oberg, David K Stammers, Anna Karlsson, Jan Balzarini | The phenylmethylthiazolylthiourea non... | |
| 2004 | Kenji Kitano, Satoru Kohgo, Kohei Yamada, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui | Attempt to reduce cytotoxicity by syn... | |
| 2004 | Claudia M D'Abramo, Luciano Cellai, Matthias Götte | Excision of incorporated nucleotide a... | |
| 2004 | Esther W Hou, Rajendra Prasad, William A Beard, Samuel H Wilson | High-level expression and purificatio... | |
| 2004 | George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Kalavathy Sitaraman, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice | Site- and subunit-specific incorporat... | |
| 2004 | Florence Doualla-Bell, Simane Gaseitsiwe, Thumbi Ndungú, Musetsanagepe Modukanele, Trevor Peter, Vladimir Novitsky, Ndwapi Ndwapi, Gaolathe Tendani, Ava Avalos, William Wester, Hermann Bussmann, Peter Cardiello, Richard G Marlink, Howard Moffat, Ibou Thior, Mark A. Wainberg, Max Essex | Mutations and polymorphisms associate... | |
| 2004 | Mark A. Wainberg | The impact of the M184V substitution ... | |
| 2004 | Steve Tuske, Stefan G Sarafianos, Arthur D Clark, Jianping Ding, Lisa K Naeger, Kirsten L White, Michael D Miller, Craig S Gibbs, Paul L Boyer, Patrick K Clark, Gang Wang, Barbara L Gaffney, Roger A Jones, Donald M Jerina, Stephen H Hughes, Edward Arnold | Structures of HIV-1 RT-DNA complexes ... | |
| 2004 | Nicolas Sluis-Cremer, Dominique Arion, Michael E Abram, Michael A. Parniak | Proteolytic processing of an HIV-1 po... | |
| 2004 | Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà | Synthesis of new 2,3-diaryl-1,3-thiaz... | |
| 2004 | Dan Turner, Ariel Roldan, Bluma G Brenner, Daniela D Moisi, Jean-Pierre Routy, Mark A. Wainberg | Variability in the PR and RT genes of... | |
| 2004 | Jan Balzarini | Current status of the non-nucleoside ... | |
| 2004 | María-José Camarasa, Ana San-Félix, Sonsoles Velázquez, María-Jesús Pérez-Pérez, Federico Gago, Jan Balzarini | TSAO compounds: the comprehensive sto... | |
| 2004 | Maximilian A Silvestri, Muthukaman Nagarajan, Erik De Clercq, Christophe Pannecouque, Mark Cushman | Design, synthesis, anti-HIV activitie... | |
| 2004 | Kalyan Das, Arthur D Clark, Paul J Lewi, Jan Heeres, Marc R De Jonge, Lucien M H Koymans, H Maarten Vinkers, Frederik Daeyaert, Donald W Ludovici, Michael J Kukla, Bart De Corte, Robert W Kavash, Chih Y Ho, Hong Ye, Mark A Lichtenstein, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Paul L Boyer, Patrick K Clark, Stephen H Hughes, Paul A J Janssen, Edward Arnold | Roles of conformational and positiona... | |
| 2004 | CF Perno, Emanuela Balestra, M Francesconi, D Abdelahad, Raffaele Caliò, Jan Balzarini, Stefano Aquaro | Antiviral profile of HIV inhibitors i... | |
| 2004 | Yanping He, Fener Chen, Guangfu Sun, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | 5-Alkyl-2-[(aryl and alkyloxylcarbony... | |
| 2004 | Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Zeev Rosberger, Michel Roger, Mark A. Wainberg | Diminished representation of HIV-1 va... | |
| 2003 | Peter R Meyer, Johan Lennerstrand, Suzanne E Matsuura, Brendan A Larder, Walter A Scott | Effects of dipeptide insertions betwe... | |
| 2003 | Maria Letizia Barreca, Alba Chimirri, Erik De Clercq, Laura De Luca, Anna-Maria Monforte, Pietro Monforte, Angela Rao, Maria Zappalà | Anti-HIV agents: design and discovery... | |
| 2003 | Marilyn B Kroeger Smith, Brian M Hose, Arie Hawkins, James Lipchock, David W Farnsworth, Robert C Rizzo, Julian Tirado-Rives, Edward Arnold, Weiming Zhang, Stephen H Hughes, William L Jorgensen, Christopher J Michejda, Richard H Smith | Molecular modeling calculations of HI... | |
| 2003 | Nicolas Sluis-Cremer, Ellis Kempner, Michael A. Parniak | Structure-activity relationships in H... | |
| 2003 | Michael A. Parniak, Kyung-Lyum Min, Scott R Budihas, Stuart F J Le Grice, John A Beutler | A fluorescence-based high-throughput ... | |
| 2003 | Romas Geleziunas, Karen Gallagher, Hangchun Zhang, Lee Bacheler, Sena Garber, Jing-Tao Wu, Guoen Shi, Michael J Otto, Raymond F Schinazi, Susan Erickson-Viitanen | HIV-1 resistance profile of the novel... | |
| 2003 | Joel E Gallant, Peter Z Gerondelis, Mark A. Wainberg, Nancy S Shulman, Richard H Haubrich, Marty St Clair, Ernest R Lanier, Nicholas S Hellmann, Douglas D Richman | Nucleoside and nucleotide analogue re... | RT,Associated condition,All properties |
| 2003 | Tokumi Maruyama, Shigetada Kozai, Tetsuo Yamasaki, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoeck, Graciella Andrei, Erik De Clercq | Synthesis and antiviral activity of 1... | |
| 2003 | Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, Jingshan Ren, David I Stuart, David K Stammers | Cloning, expression, purification, an... | |
| 2003 | Myriam Witvrouw, Christophe Pannecouque, Valery Fikkert, Anke Hantson, Barbara Van Remoortel, Marjan Hezareh, Erik De Clercq, Stephen J Brown | Potent and selective inhibition of HI... | |
| 2003 | Karidia Diallo, Bluma G Brenner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Matthias Götte, Mark A. Wainberg | The M184V substitution in human immun... | |
| 2003 | Wei Huang, Andrea Gamarnik, Kay Limoli, Christos J Petropoulos, Jeannette M Whitcomb | Amino acid substitutions at position ... | |
| 2003 | Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg | Negative effect of the M184V mutation... | |
| 2003 | William A Beard, Samuel H Wilson | Structural insights into the origins ... | |
| 2003 | Adrian S Ray, Eisuke Murakami, Aravind Basavapathruni, Joseph A Vaccaro, Dagny Ulrich, Chung K Chu, Raymond F Schinazi, Karen S Anderson | Probing the molecular mechanisms of A... | |
| 2003 | Jaroslaw Poznanski, Maria Bretner, Tadeusz Kulikowski, Jan Balzarini, Arthur Van Aerschot, Erik De Clercq | Synthesis, solution conformation and ... | |
| 2003 | Adrian S Ray, Raymond F Schinazi, Eisuke Murakami, Aravind Basavapathruni, Junxing Shi, Suzana M Zorca, Chung K Chu, Karen S Anderson | Probing the mechanistic consequences ... | RT,Associated condition,All properties |
| 2003 | Susan E Lim, Mikhail V Ponamarev, Matthew J Longley, William C Copeland | Structural determinants in human DNA ... | |
| 2003 | Yudong Quan, Bluma G Brenner, Maureen Oliveira, Mark A. Wainberg | Lamivudine can exert a modest antivir... | |
| 2003 | Bluma G Brenner, Dan Turner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Mauricio Carobene, Richard G Marlink, Jonathan Schapiro, Michel Roger, Mark A. Wainberg | A V106M mutation in HIV-1 clade C vir... | |
| 2003 | Ge Meng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque | Nonnucleoside HIV-1 reverse transcrip... | |
| 2003 | Karidia Diallo, Bruno Marchand, Xin Wei, Luciano Cellai, Matthias Götte, Mark A. Wainberg | Diminished RNA primer usage associate... | |
| 2003 | Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini | Inhibition of human immunodeficiency ... | |
| 2003 | Peter R Meyer, Suzanne E Matsuura, Dianna Zonarich, Rahul R Chopra, Eric Pendarvis, Holly Z Bazmi, John W Mellors, Walter A Scott | Relationship between 3'-azido-3'-deox... | |
| 2003 | Eisuke Murakami, Joy Y Feng, Harold R Lee, Jeremiah Hanes, Kenneth A Johnson, Karen S Anderson | Characterization of novel reverse tra... | |
| 2003 | María-Cruz Bonache, Cristina Chamorro, Esther Lobatón, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, Ana San-Félix | Structure-activity relationship studi... | |
| 2003 | Bruno Marchand, Matthias Götte | Site-specific footprinting reveals di... | |
| 2003 | Cathryn A Shaw-Reid, Vandna Munshi, Pia Graham, Abigail Wolfe, Marc Witmer, Renee Danzeisen, David B Olsen, Steven S Carroll, Mark Embrey, John S Wai, Michael D Miller, James L Cole, Daria J Hazuda | Inhibition of HIV-1 ribonuclease H by... | |
| 2003 | Boulbaba Selmi, Jerome Deval, Karine Alvarez, Joelle Boretto, Simon Sarfati, Catherine Guerreiro, Bruno Canard | The Y181C substitution in 3'-azido-3'... | |
| 2003 | Marie L Coté, Mark Pflomm, Millie M Georgiadis | Staying straight with A-tracts: a DNA... | |
| 2003 | Giuseppina Blanca, Fausto Baldanti, Stefania Paolucci, Alexander Yu Skoblov, Lyubov Victorova, Ulrich Hübscher, Giuseppe Gerna, Silvio Spadari, Giovanni Maga | Nevirapine resistance mutation at cod... | |
| 2003 | Qian Zhao, Hong Lu, Dominique Schols, Erik De Clercq, Shibo Jiang | Development of a cell-based enzyme-li... | |
| 2003 | Mélanie Girouard, Karidia Diallo, Bruno Marchand, Suzanne McCormick, Matthias Götte | Mutations E44D and V118I in the rever... | |
| 2003 | Evguenia S Svarovskaia, Sara R Cheslock, Wen-Hui Zhang, Wei-Shau Hu, Vinay K Pathak | Retroviral mutation rates and reverse... | |
| 2003 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Mutation of amino acids in the connec... | |
| 2003 | Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes | Mutations in the 5' end of the human ... | |
| 2003 | Sanjay U C Sankatsing, Gerrit J Weverling, Monika Peeters, Gerben van't Klooster, Boris Gruzdev, Aza Rakhmanova, Sven A Danner, Suzanne Jurriaans, Jan M Prins, Joep M A Lange | TMC125 exerts similar initial antivir... | |
| 2003 | Martin Stürmer, Schlomo Staszewski, Hans-Wilhelm Doerr, Brendan A Larder, Stuart Bloor, Kurt Hertogs | Correlation of phenotypic zidovudine ... | |
| 2003 | Harold R Lee, Jeremiah Hanes, Kenneth A Johnson | Toxicity of nucleoside analogues used... | |
| 2003 | Giuseppina Blanca, Igor V Shevelev, Kristijan Ramadan, Giuseppe Villani, Silvio Spadari, Ulrich Hübscher, Giovanni Maga | Human DNA polymerase lambda diverged ... | |
| 2003 | Angelo Ranise, Andrea Spallarossa, Silvia Schenone, Olga Bruno, Francesco Bondavalli, Laura Vargiu, Tiziana Marceddu, Massimo Mura, Paolo La Colla, Alessandra Pani | Design, synthesis, SAR, and molecular... | |
| 2003 | Klaus Klumpp, Julie Qi Hang, Surendran Rajendran, Yanli Yang, Andre Derosier, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin | Two-metal ion mechanism of RNA cleava... | |
| 2003 | Yongseok Choi, Clifford George, Maria J Comin, Joseph J Barchi, Hak Sung Kim, Kenneth A Jacobson, Jan Balzarini, Hiroyuki Mitsuya, Paul L Boyer, Stephen H Hughes, Victor E Marquez | A conformationally locked analogue of... | |
| 2003 | Marie-Pierre Golinelli, Stephen H Hughes | Secondary structure in the nucleic ac... | |
| 2003 | Stefania Paolucci, Fausto Baldanti, Marco Tinelli, Giovanni Maga, Giuseppe Gerna | Detection of a new HIV-1 reverse tran... | |
| 2003 | J Gerardo García-Lerma, Hamish MacInnes, Diane Bennett, Patrick Reid, Soumya Nidtha, Hillard Weinstock, Jonathan E Kaplan, Walid Heneine | A novel genetic pathway of human immu... | |
| 2003 | Lingling Shen, Jianhua Shen, Xiaomin Luo, Feng Cheng, Yechun Xu, Kaixian Chen, Edward Arnold, Jianping Ding, Hualiang Jiang | Steered molecular dynamics simulation... | |
| 2003 | Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini | Novel human immunodeficiency virus (H... | |
| 2003 | Marilyn B Kroeger Smith, Sandra Ruby, Stanislav Horouzhenko, Bryan Buckingham, Julia Richardson, Ina Puleri, Emily Potts, William L Jorgensen, Edward Arnold, Weiming Zhang, Stephen H Hughes, Christopher J Michejda, Richard H Smith | HIV-1 reverse transcriptase variants:... | |
| 2003 | Irene M Lagoja, Christophe Pannecouque, Arthur Van Aerschot, Myriam Witvrouw, Zeger Debyser, Jan Balzarini, Piet Herdewijn, Erik De Clercq | N-aminoimidazole derivatives inhibiti... | |
| 2003 | Koyo Ariyoshi, Masakazu Matsuda, Hideka Miura, Sachiko Tateishi, Kaneo Yamada, Wataru Sugiura | Patterns of point mutations associate... | |
| 2003 | Jan Balzarini, Erik De Clercq, Beata Kaminska, Andrzej Orzeszko | Synthesis and antiviral activity of s... | |
| 2002 | Joke Snoeck, Sonia Van Dooren, Kristel Van Laethem, Inge Derdelinckx, Eric Van Wijngaerden, Erik De Clercq, Anne-Mieke Vandamme | Prevalence and origin of HIV-1 group ... | |
| 2002 | Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg | Co-receptor usage and HIV-1 intra-cla... | |
| 2002 | A Geoffrey Skillman, Karl W Maurer, Diana C Roe, Margaret J Stauber, Dolan Eargle, Todd J A Ewing, Angelika Muscate, Elisabeth Davioud-Charvet, Maxine V Medaglia, Robert J Fisher, Edward Arnold, Hong Qiang Gao, Robert W Buckheit, Paul L Boyer, Stephen H Hughes, Irwin D Kuntz, George L Kenyon | A novel mechanism for inhibition of H... | |
| 2002 | Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg | Polymorphisms of cytotoxic T-lymphocy... | |
| 2002 | Bluma G Brenner, Dan Turner, Mark A. Wainberg | HIV-1 drug resistance: can we overcome? | |
| 2002 | Patrick K O'Neil, Guoli Sun, Hong Yu, Yacov Ron, Joseph P Dougherty, Bradley D Preston | Mutational analysis of HIV-1 long ter... | |
| 2002 | R Masciari, L Cosco, M C Diaco, Dora N Della, T Ferraro, T Raimondi, B Ruperti, E Santandrea | HIV-1: a case of RT67 deletion in a m... | |
| 2002 | Brigitte Montes, Michel Segondy | Prevalence of the mutational pattern ... | |
| 2002 | Yven Van Herrewege, Lieve Penne, Chris Vereecken, Katrien Fransen, Guido van der Groen, Luc Kestens, Jan Balzarini, Guido Vanham | Activity of reverse transcriptase inh... | |
| 2002 | Janina Cramer, Michael Strerath, Andreas Marx, Tobias Restle | Exploring the effects of active site ... | RT,Associated condition,All properties |
| 2002 | Timothy S Fisher, Vinayaka R Prasad | Substitutions of Phe61 located in the... | RT,Associated condition,All properties |
| 2002 | Karen S Anderson | Perspectives on the molecular mechani... | RT,Associated condition,All properties |
| 2002 | Christopher J Hollowood, Steven V Ley, Shigeo Yamanoi | Synthesis of taurospongin A: a potent... | |
| 2002 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | The M184V mutation reduces the select... | |
| 2002 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Nucleoside analog resistance caused b... | |
| 2002 | Robert L Lobato, Eun-Young Kim, Ronald M Kagan, Thomas C Merigan | Genotypic and phenotypic analysis of ... | |
| 2002 | Laurent Andréoletti, Laurence Weiss, Ali Si-Mohamed, Christophe Piketty, Thierry Prazuck, Gérard Calamy, Jean-Elie Malkin, Mathieu Matta, François-Xavier Mbopi-Kéou, François Clavel, Michel D Kazatchkine, Laurent Bélec | Multidrug-resistant HIV-1 RNA and pro... | |
| 2002 | Kirsten L White, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Michael D Miller, Lisa K Naeger | Molecular mechanisms of resistance to... | |
| 2002 | P Richard Harrigan, Mahboob Salim, David K Stammers, Brian Wynhoven, Zabrina L Brumme, Paula McKenna, Brendan A Larder, S D Kemp | A mutation in the 3' region of the hu... | |
| 2002 | Peter R Meyer, Suzanne E Matsuura, Adviye A Tolun, Ingrid Pfeifer, Antero G So, John W Mellors, Walter A Scott | Effects of specific zidovudine resist... | |
| 2002 | Dominique Arion, Nicolas Sluis-Cremer, Kyung-Lyum Min, Michael E Abram, Ronald S Fletcher, Michael A. Parniak | Mutational analysis of Tyr-501 of HIV... | |
| 2002 | Esther Lobatón, Fátima Rodríguez-Barrios, Federico Gago, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez | Synthesis of 3' '-substituted TSAO de... | |
| 2002 | Nobuyuki Kasai, Yoshiyuki Mizushina, Fumio Sugawara, Kengo Sakaguchi | Three-dimensional structural model an... | |
| 2002 | Yoshiyuki Mizushina, Chikako Murakami, Keisuke Ohta, Hirosato Takikawa, Kenji Mori, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi | Selective inhibition of the activitie... | |
| 2002 | Marie-Pierre Golinelli, Stephen H Hughes | Nontemplated nucleotide addition by H... | |
| 2002 | Stefano Aquaro, Raffaele Caliò, Jan Balzarini, Maria Concetta Bellocchi, Enrico Garaci, CF Perno | Macrophages and HIV infection: therap... | |
| 2002 | Jason W Rausch, Daniela Lener, Jennifer T Miller, John G Julias, Stephen H Hughes, Stuart F J Le Grice | Altering the RNase H primer grip of h... | |
| 2002 | Marie-Pierre Golinelli, Stephen H Hughes | Nontemplated base addition by HIV-1 R... | |
| 2002 | Marinela Perpelescu, Jun'ichi Kobayashi, Miho Furuta, Yasutomo Ito, Shunji Izuta, Masaharu Takemura, Motoshi Suzuki, Shonen Yoshida | Novel phenalenone derivatives from a ... | |
| 2002 | N McLellan, Xin Wei, Bruno Marchand, Mark A. Wainberg, Matthias Götte | Nonradioactive detection of retrovira... | |
| 2002 | Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg | The M184V mutation in HIV-1 reverse t... | |
| 2002 | Adrienne M Woodside, F Peter Guengerich | Misincorporation and stalling at O(6)... | |
| 2002 | Adrienne M Woodside, F Peter Guengerich | Effect of the O6 substituent on misin... | |
| 2002 | Adrian S Ray, Aravind Basavapathruni, Karen S Anderson | Mechanistic studies to understand the... | |
| 2002 | Phillip P Chamberlain, Jingshan Ren, Charles E Nichols, L Douglas, Johan Lennerstrand, Brendan A Larder, David I Stuart, David K Stammers | Crystal structures of Zidovudine- or ... | |
| 2002 | Mickael Rigourd, Chantal Ehresmann, Michael A. Parniak, Bernard Ehresmann, Roland Marquet | Primer unblocking and rescue of DNA s... | |
| 2002 | Dimitrios Motakis, Michael A. Parniak | A tight-binding mode of inhibition is... | |
| 2002 | Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak | Destabilization of the HIV-1 reverse ... | |
| 2002 | Joeri Auwerx, Thomas W North, Bradley D Preston, George J Klarmann, Erik De Clercq, Jan Balzarini | Chimeric human immunodeficiency virus... | |
| 2002 | Antonio Mas, Blanca M Vázquez-Alvarez, Esteban Domingo, L Menéndez-Arias | Multidrug-resistant HIV-1 reverse tra... | |
| 2002 | Louis M Mansky | HIV mutagenesis and the evolution of ... | |
| 2002 | Lisa K Naeger, Nicolas A Margot, Michael D Miller | ATP-dependent removal of nucleoside r... | |
| 2002 | John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Mutations in the RNase H domain of HI... | |
| 2002 | Jingshan Ren, Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, David I Stuart, David K Stammers | Structure of HIV-2 reverse transcript... | |
| 2002 | L Menéndez-Arias | Molecular basis of fidelity of DNA sy... | |
| 2002 | Janice D Pata, Bradford R King, Thomas A Steitz | Assembly, purification and crystalliz... | |
| 2002 | Qingli Shi, Kamalendra Singh, Aashish Srivastava, Neerja Kaushik, Mukund J Modak | Lysine 152 of MuLV reverse transcript... | |
| 2002 | Stefan G Sarafianos, Arthur D Clark, Kalyan Das, Steve Tuske, Jens J Birktoft, Palanichamy Ilankumaran, Andagar R Ramesha, Jane M Sayer, Donald M Jerina, Paul L Boyer, Stephen H Hughes, Edward Arnold | Structures of HIV-1 reverse transcrip... | |
| 2002 | Michael Strerath, Janina Cramer, Tobias Restle, Andreas Marx | Implications of active site constrain... | |
| 2002 | Fabienne Brulé, Roland Marquet, Liwei Rong, Mark A. Wainberg, Bernard P Roques, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann | Structural and functional properties ... | |
| 2002 | Giuseppe Campiani, Anna Ramunno, Giovanni Maga, Vito Nacci, Caterina Fattorusso, Bruno Catalanotti, Elena Morelli, Ettore Novellino | Non-nucleoside HIV-1 reverse transcri... | |
| 2002 | Giovanni Maga, Silvio Spadari | Combinations against combinations: as... | |
| 2002 | Jimmy Lindberg, Snaevar Sigurdsson, Seved Löwgren, Hans O Andersson, Christer Sahlberg, Rolf Noréen, Kerstin Fridborg, Haijiang Zhang, Torsten Unge | Structural basis for the inhibitory e... | |
| 2002 | Erik De Clercq | Highlights in the development of new ... | |
| 2002 | Erik De Clercq | New anti-HIV agents and targets. | |
| 2002 | Wim Pluymers, Godwin Pais, Bénédicte Van Maele, Christophe Pannecouque, Valery Fikkert, Terrence R Burke, Erik De Clercq, Myriam Witvrouw, Nouri Neamati, Zeger Debyser | Inhibition of human immunodeficiency ... | |
| 2002 | Koen K A Van Rompay, Tim B Matthews, Joanne Higgins, Don R Canfield, Ross P Tarara, Mark A. Wainberg, Raymond F Schinazi, Niels C Pedersen, Thomas W North | Virulence and reduced fitness of simi... | |
| 2002 | Zeger Debyser, Peter Cherepanov, Bénédicte Van Maele, Erik De Clercq, Myriam Witvrouw | In search of authentic inhibitors of ... | |
| 2002 | Christophe Pannecouque, Wim Pluymers, Bénédicte Van Maele, Victor Tetz, Peter Cherepanov, Erik De Clercq, Myriam Witvrouw, Zeger Debyser | New class of HIV integrase inhibitors... | |
| 2002 | Erik De Clercq | New developments in anti-HIV chemothe... | |
| 2001 | Fátima Rodríguez-Barrios, C Pérez, Esther Lobatón, Sonsoles Velázquez, Cristina Chamorro, Ana San-Félix, María-Jesús Pérez-Pérez, María-José Camarasa, H Pelemans, Jan Balzarini, Federico Gago | Identification of a putative binding ... | |
| 2001 | Jan Balzarini, María-José Camarasa, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, CF Perno, Erik De Clercq, J N Anderson, Anna Karlsson | Exploitation of the low fidelity of h... | |
| 2001 | K E Squires | An introduction to nucleoside and nuc... | |
| 2001 | Johan Lennerstrand, Kurt Hertogs, David K Stammers, Brendan A Larder | Correlation between viral resistance ... | |
| 2001 | L Menéndez-Arias, A Abraha, ME Quiñones-Mateu, Antonio Mas, M J Camarasa, E J Arts | Functional characterization of chimer... | |
| 2001 | Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Paul L Boyer, Paul Lewi, Paul A J Janssen, Jörg-Peter Kleim, M Rösner, Stephen H Hughes, Edward Arnold | The Lys103Asn mutation of HIV-1 RT: a... | |
| 2001 | H Pelemans, Robert Esnouf, K L Min, M Parniak, Erik De Clercq, Jan Balzarini | Mutations at amino acid positions 63,... | |
| 2001 | Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | RNase H cleavage of the 5' end of the... | |
| 2001 | Stephen H Hughes | Molecular matchmaking: NNRTIs can enh... | |
| 2001 | Cristina Chamorro, Esther Lobatón, María-Cruz Bonache, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, Ana San-Félix, María-José Camarasa | Identification of a novel family of n... | |
| 2001 | Jan Balzarini, Erik De Clercq | Rapid alternation of drug therapy is ... | |
| 2001 | Z Sevilya, S Loya, Stephen H Hughes, A Hizi | The ribonuclease H activity of the re... | |
| 2001 | Lisa K Naeger, Michael D Miller | Mechanisms of HIV-1 nucleoside revers... | |
| 2001 | A Martinez, C Gil, A Castro, C Perez, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq | Anti-HIV-1 activity of benzothiadiazi... | |
| 2001 | Donald W Ludovici, Michael J Kukla, P G Grous, S Krishnan, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Erik De Clercq, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | Elena N Peletskaya, Paul L Boyer, Alex A Kogon, Patrick K Clark, Heiko Kroth, Jane M Sayer, Donald M Jerina, Stephen H Hughes | Cross-linking of the fingers subdomai... | |
| 2001 | I A Drachkova, Irina O Petruseva, I V Safronov, A L Zakharenko, G V Shishkin, Olga I Lavrik, Svetlana N Khodyreva | [Reagents for modification of protein... | |
| 2001 | G Tachedjian, M Orlova, Stefan G Sarafianos, Edward Arnold, S P Goff | Nonnucleoside reverse transcriptase i... | |
| 2001 | Phillip A Furman, J Jeffrey, L L Kiefer, Joy Y Feng, Karen S Anderson, K Borroto-Esoda, E Hill, William C Copeland, Chung K Chu, J P Sommadossi, I Liberman, Raymond F Schinazi, George R Painter | Mechanism of action of 1-beta-D-2,6-d... | |
| 2001 | Masanori Kameoka, Liwei Rong, Matthias Götte, Chen Liang, Rodney S Russell, Mark A. Wainberg | Role for human immunodeficiency virus... | |
| 2001 | Donald W Ludovici, Robert W Kavash, Michael J Kukla, Chih Y Ho, Hong Ye, B L De Corte, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, H E Moereels, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Paul J Lewi, Kalyan Das, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | Paul L Boyer, Hong Qiang Gao, Patrick K Clark, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | YADD mutants of human immunodeficienc... | |
| 2001 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Selective excision of AZTMP by drug-r... | |
| 2001 | J Y Wang, Hong Ling, Wei Wen Yang, R Craigie | Structure of a two-domain fragment of... | |
| 2001 | Alba Chimirri, Pietro Monforte, Angela Rao, Maria Zappalà, Anna-Maria Monforte, G De Sarro, Christophe Pannecouque, Myriam Witvrouw, Jan Balzarini, Erik De Clercq | Synthesis, biological activity, pharm... | |
| 2001 | J L Hammond, D L Koontz, Holly Z Bazmi, J R Beadle, S E Hostetler, G D Kini, Kathy A Aldern, Douglas D Richman, Karl Y Hostetler, John W Mellors | Alkylglycerol prodrugs of phosphonofo... | |
| 2001 | V Molteni, J Greenwald, D Rhodes, Y Hwang, W Kwiatkowski, F D Bushman, J S Siegel, S Choe | Identification of a small-molecule bi... | |
| 2001 | Erik De Clercq | New developments in anti-HIV chemothe... | |
| 2001 | Jennifer T Miller, Bernard Ehresmann, Ulrich Hübscher, Stuart F J Le Grice | A novel interaction of tRNA(Lys,3) wi... | |
| 2001 | Erik De Clercq, Dominique Schols | Inhibition of HIV infection by CXCR4 ... | |
| 2001 | Taurai Tasara, Giovanni Maga, Michael O Hottiger, Ulrich Hübscher | HIV-1 reverse transcriptase and integ... | |
| 2001 | Giovanni Maga, Anna Ramunno, Vito Nacci, Giada A Locatelli, Silvio Spadari, Isabella Fiorini, Fausto Baldanti, Stefania Paolucci, Maurizio Zavattoni, Alberto Bergamini, Bruno Galletti, S Muck, Ulrich Hubscher, Gianluca Giorgi, G Guiso, S Caccia, Giuseppe Campiani | The stereoselective targeting of a sp... | |
| 2001 | Giuseppe Campiani, F Aiello, M Fabbrini, Elena Morelli, Anna Ramunno, S Armaroli, Vito Nacci, A Garofalo, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, L Ventura, B Bongiovanni, M Capozzi, F Bolacchi, Stefano Marini, Massimo Coletta, G Guiso, S Caccia | Quinoxalinylethylpyridylthioureas (QX... | |
| 2001 | Hiroshi Ohrui, Hiroyuki Mitsuya | 4'-C-substituted-2'-deoxynucleosides:... | |
| 2001 | M Madrid, J A Lukin, J D Madura, Jianping Ding, Edward Arnold | Molecular dynamics of HIV-1 reverse t... | |
| 2001 | Ei-Ichi Kodama, Satoru Kohgo, Kenji Kitano, H Machida, Hiroyuki Gatanaga, S Shigeta, Masao Matsuoka, Hiroshi Ohrui, Hiroyuki Mitsuya | 4'-Ethynyl nucleoside analogs: potent... | |
| 2001 | J E Fitzgibbon, B DiCola, Edward Arnold, Kalyan Das, B E Sha, J C Pottage, R Nahass, S Gaur, J F John | HIV-1 reverse transcriptase mutations... | |
| 2001 | Wim Pluymers, Erik De Clercq, Zeger Debyser | HIV-1 integration as a target for ant... | |
| 2001 | Stefan G Sarafianos, Kalyan Das, C Tantillo, Arthur D Clark, Jianping Ding, J M Whitcomb, Paul L Boyer, Stephen H Hughes, Edward Arnold | Crystal structure of HIV-1 reverse tr... | |
| 2001 | Jingshan Ren, C Nichols, L Bird, P Chamberlain, Kurt L Weaver, S Short, David I Stuart, David K Stammers | Structural mechanisms of drug resista... | |
| 2001 | R Hobi, Ulrich Hübscher, K Neftel, E Alteri, B Poncioni, M R Walker, K Woods-Cook, P Schneider, J K Lazdins | Anti-HIV-1 activity in vitro of cefta... | |
| 2001 | Liwei Rong, Chen Liang, M Hsu, Xiaofeng Guo, Bernard P Roques, Mark A. Wainberg | HIV-1 nucleocapsid protein and the se... | |
| 2001 | Donald W Ludovici, B L De Corte, Michael J Kukla, Hong Ye, Chih Y Ho, Mark A Lichtenstein, Robert W Kavash, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Kalyan Das, Edward Arnold, Paul A J Janssen | Evolution of anti-HIV drug candidates... | |
| 2001 | Li Fan, Laurie S Kaguni | Multiple regions of subunit interacti... | |
| 2001 | G H Kijak, S E Pampuro, M M Avila, C Zala, P Cahn, Mark A. Wainberg, H Salomón | Resistance profiles to antiretroviral... | |
| 2001 | A L Zakharenko, Dmitry M Kolpashchikov, Svetlana N Khodyreva, Olga I Lavrik, L Menéndez-Arias | Investigation of the dNTP-binding sit... | |
| 2001 | M D Driscoll, Marie-Pierre Golinelli, Stephen H Hughes | In vitro analysis of human immunodefi... | |
| 2001 | Paul L Boyer, Hong Qiang Gao, P Frank, Patrick K Clark, Stephen H Hughes | The basic loop of the RNase H domain ... | |
| 2001 | H Pelemans, A Aertsen, Kristel Van Laethem, A-M Vandamme, Erik De Clercq, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, María-José Camarasa, Jan Balzarini | Site-directed mutagenesis of human im... | |
| 2001 | M Lavigne, L Polomack, H Buc | Structures of complexes formed by HIV... | |
| 2001 | M Gutiérrez-Rivas, L Menéndez-Arias | A mutation in the primer grip region ... | |
| 2001 | Joseph H Chan, J S Hong, R N Hunter , G F Orr, Jill R Cowan, D B Sherman, S M Sparks, B E Reitter, C Webster Andrews, Richard J Hazen, M St Clair, Lawrence R Boone, Robert G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, R J Ott, Jingshan Ren, A Hopkins, David I Stuart, David K Stammers | 2-Amino-6-arylsulfonylbenzonitriles a... | |
| 2001 | Matthias Götte, Masanori Kameoka, N McLellan, Luciano Cellai, Mark A. Wainberg | Analysis of efficiency and fidelity o... | |
| 2001 | Catherine Isel, Chantal Ehresmann, P Walter, Bernard Ehresmann, Roland Marquet | The emergence of different resistance... | |
| 2000 | H Pelemans, Robert Esnouf, Erik De Clercq, Jan Balzarini | Mutational analysis of trp-229 of hum... | |
| 2000 | Jan Balzarini | Evaluation of Compounds Against Recom... | |
| 2000 | A-M Vandamme, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Kristel Van Laethem, J C Schmit, J Desmyter, Erik De Clercq | Evaluating Clinical Isolates for Thei... | |
| 2000 | N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of hum... | |
| 2000 | Matthias Götte, Dominique Arion, Michael A. Parniak, Mark A. Wainberg | The M184V mutation in the reverse tra... | |
| 2000 | L T Bacheler, E D Anton, P Kudish, D Baker, J Bunville, K Krakowski, L Bolling, M Aujay, X V Wang, D Ellis, M F Becker, A L Lasut, H J George, D R Spalding, G Hollis, K Abremski | Human immunodeficiency virus type 1 m... | |
| 2000 | V Miller, M Ait-Khaled, C Stone, P Griffin, D Mesogiti, A Cutrell, R Harrigan, Schlomo Staszewski, C Katlama, G Pearce, M Tisdale | HIV-1 reverse transcriptase (RT) geno... | |
| 2000 | A J Brown, H M Precious, Jeannette M Whitcomb, J K Wong, M Quigg, Wei Huang, E S Daar, R T D'Aquila, P H Keiser, E Connick, Nicholas S Hellmann, Christos J Petropoulos, Douglas D Richman, S J Little | Reduced susceptibility of human immun... | |
| 2000 | Kristel Van Laethem, J C Schmit, H Pelemans, Jan Balzarini, Myriam Witvrouw, María-Jesús Pérez-Pérez, María-José Camarasa, R M Esnouf, Stefano Aquaro, A Cenci, CF Perno, P Hermans, S Sprecher, L Ruiz, B Clotet, Eric Van Wijngaerden, M Van Ranst, J Desmyter, Erik De Clercq, A-M Vandamme | Presence of 2',5'-Bis-O-(tert-butyldi... | |
| 2000 | Hong Qiang Gao, Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | The role of steric hindrance in 3TC r... | |
| 2000 | C de Mendoza, V Soriano, C Briones, O Gallego, P Barreiro, A Alvarez, J González-Lahoz | Emergence of zidovudine resistance in... | |
| 2000 | P Bonfanti, I Faggion, S La Seta Catamancio, M Violin, C Balotta, S Rusconi | Response to antiretroviral therapy in... | |
| 2000 | Dominique Arion, Nicolas Sluis-Cremer, Michael A. Parniak | Mechanism by which phosphonoformic ac... | |
| 2000 | F S Shah, Kenneth A Curr, Monica E Hamburgh, M Parniak, Hiroyuki Mitsuya, J G Arnez, Vinayaka R Prasad | Differential influence of nucleoside ... | |
| 2000 | Christos J Petropoulos, N T Parkin, K L Limoli, Y S Lie, Terri Wrin, Wei Huang, H Tian, D Smith, G A Winslow, D J Capon, Jeannette M Whitcomb | A novel phenotypic drug susceptibilit... | |
| 2000 | Matthias Götte, Mark A. Wainberg | Biochemical mechanisms involved in ov... | |
| 2000 | G J Latham, E Forgacs, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd | Vertical-scanning mutagenesis of a cr... | |
| 2000 | S Najmudin, Marie L Coté, D Sun, S Yohannan, Sherwin P Montano, J Gu, Millie M Georgiadis | Crystal structures of an N-terminal f... | |
| 2000 | Nicolas Sluis-Cremer, G I Dmitrienko, Jan Balzarini, María-José Camarasa, Michael A. Parniak | Human immunodeficiency virus type 1 r... | |
| 2000 | Michael A. Parniak, Nicolas Sluis-Cremer | Inhibitors of HIV-1 reverse transcrip... | |
| 2000 | Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak | Molecular mechanisms of HIV-1 resista... | |
| 2000 | E P Coakley, J M Gillis, S M Hammer | Phenotypic and genotypic resistance p... | |
| 2000 | Neerja Kaushik, T T Talele, P K Pandey, D Harris, P N Yadav, V N Pandey | Role of glutamine 151 of human immuno... | |
| 2000 | Nicolas Sluis-Cremer, Dominique Arion, Neerja Kaushik, H Lim, Michael A. Parniak | Mutational analysis of Lys65 of HIV-1... | |
| 2000 | K K Weiss, S J Isaacs, N H Tran, Elinor T Adman, Baek Kim | Molecular architecture of the mutagen... | |
| 2000 | C E Cases-Gonzalez, M Gutierrez-Rivas, L Menéndez-Arias | Coupling ribose selection to fidelity... | |
| 2000 | Lawrence A Loeb, J I Mullins | Lethal mutagenesis of HIV by mutageni... | |
| 2000 | H Salomon, Mark A. Wainberg, Bluma G Brenner, Yudong Quan, D Rouleau, P Coté, R LeBlanc, E Lefebvre, Bonnie Spira, C Tsoukas, Rafick-Pierre Sekaly, Brian Conway, D Mayers, Jean-Pierre Routy | Prevalence of HIV-1 resistant to anti... | |
| 2000 | A Khorchid, H Javanbakht, S Wise, R Halwani, Michael A. Parniak, Mark A. Wainberg, Lawrence Kleiman | Sequences within Pr160gag-pol affecti... | |
| 2000 | Bluma G Brenner, Mark A. Wainberg, H Salomon, D Rouleau, A Dascal, Bonnie Spira, Rafick-Pierre Sekaly, Brian Conway, Jean-Pierre Routy | Resistance to antiretroviral drugs in... | |
| 2000 | N Richard, H Salomon, Maureen Oliveira, R Rando, T Mansour, Z Gu, Mark A. Wainberg | Selection of resistance-conferring mu... | |
| 2000 | Paul L Boyer, Stephen H Hughes | Effects of amino acid substitutions a... | |
| 2000 | L Mu, Stefan G Sarafianos, Marc C Nicklaus, P Russ, Maqbool A Siddiqui, H Ford, Hiroyuki Mitsuya, R Le, Eiichi N Kodama, Chris Meier, T Knispel, L Anderson, Joseph J Barchi, Victor E Marquez | Interactions of conformationally bias... | |
| 2000 | Jingshan Ren, C Nichols, Louise E Bird, Tsuyoshi Fujiwara, H Sugimoto, David I Stuart, David K Stammers | Binding of the second generation non-... | |
| 2000 | Jingshan Ren, John Milton, Kurt L Weaver, Steven A Short, David I Stuart, David K Stammers | Structural basis for the resilience o... | |
| 2000 | Giuseppe Campiani, M Fabbrini, Elena Morelli, Vito Nacci, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, C Fracasso, S Caccia | Non-nucleoside HIV-1 reverse transcri... | |
| 2000 | K Nozawa, Motoshi Suzuki, Masaharu Takemura, Shonen Yoshida | In vitro expansion of mammalian telom... | |
| 2000 | Mickael Rigourd, J M Lanchy, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann, Roland Marquet | Inhibition of the initiation of HIV-1... | |
| 2000 | W R Davis, J Tomsho, S Nikam, E M Cook, D Somand, J A Peliska | Inhibition of HIV-1 reverse transcrip... | |
| 2000 | Ming Yu, W Kabat, Jian Wang | [Rapid detection of drug resistant HI... | |
| 2000 | T Imamichi, T Sinha, H Imamichi, Y M Zhang, J A Metcalf, J Falloon, H C Lane | High-level resistance to 3'-azido-3'-... | |
| 2000 | Neerja Kaushik, K Chowdhury, V N Pandey, Mukund J Modak | Valine of the YVDD motif of moloney m... | |
| 2000 | D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando | Drug resistance and drug combination ... | |
| 2000 | Myriam Witvrouw, Valery Fikkert, Wim Pluymers, B Matthews, K Mardel, Dominique Schols, J Raff, Zeger Debyser, Erik De Clercq, G Holan, Christophe Pannecouque | Polyanionic (i.e., polysulfonate) den... | |
| 2000 | A Casimiro-Garcia, Erik De Clercq, Christophe Pannecouque, Myriam Witvrouw, T L Stup, J A Turpin, Robert W Buckheit, Mark Cushman | Synthesis and anti-HIV activity of co... | |
| 2000 | Erik De Clercq | Current lead natural products for the... | |
| 2000 | Holly Z Bazmi, J L Hammond, S C Cavalcanti, Chung K Chu, Raymond F Schinazi, John W Mellors | In vitro selection of mutations in th... | |
| 2000 | K Van Vaerenbergh, Kristel Van Laethem, J Albert, Charles A B Boucher, B Clotet, M Floridia, J Gerstoft, B Hejdeman, C Nielsen, Christophe Pannecouque, L Perrin, M F Pirillo, L Ruiz, J C Schmit, F Schneider, A Schoolmeester, Rob Schuurman, H J Stellbrink, L Stuyver, J Van Lunzen, Barbara Van Remoortel, Eric Van Wijngaerden, S Vella, Myriam Witvrouw, Sabine Yerly, Erik De Clercq, J Destmyer, Anne-Mieke Vandamme | Prevalence and characteristics of mul... | |
| 2000 | Kamalendra Singh, Neerja Kaushik, J Jin, M Madhusudanan, Mukund J Modak | Role of Q190 of MuLV RT in ddNTP resi... | |
| 2000 | Myriam Witvrouw, Christophe Pannecouque, J Desmyter, Erik De Clercq, Koen Andries | In vitro evaluation of the effect of ... | |
| 2000 | H Jonckheere, Erik De Clercq, J Anné | Fidelity analysis of HIV-1 reverse tr... | |
| 2000 | H Jonckheere, J Anné, Erik De Clercq | The HIV-1 reverse transcription (RT) ... | |
| 2000 | Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Analysis of mutations at positions 11... | |
| 2000 | Jan Balzarini, Erik De Clercq, A Carbonez, V Burt, Jörg-Peter Kleim | Long-term exposure of HIV type 1-infe... | |
| 2000 | Antonio Mas, M Parera, C Briones, V Soriano, Miguel Angel Martínez, Esteban Domingo, L Menéndez-Arias | Role of a dipeptide insertion between... | |
| 2000 | Peter R Meyer, Suzanne E Matsuura, Raymond F Schinazi, Antero G So, Walter A Scott | Differential removal of thymidine nuc... | |
| 2000 | Jingshan Ren, J Diprose, J Warren, R M Esnouf, Louise E Bird, Shinji Ikemizu, M Slater, John Milton, Jan Balzarini, David I Stuart, David K Stammers | Phenylethylthiazolylthiourea (PETT) n... | |
| 2000 | T V Rao, M T Haber, Jane M Sayer, Donald M Jerina | Incorporation of 4-thiothymidine into... | |
| 2000 | Kurt Hertogs, Stuart Bloor, V De Vroey, C van Den Eynde, Pascale Dehertogh, A van Cauwenberge, Martin Stürmer, T Alcorn, S Wegner, M van Houtte, V Miller, Brendan A Larder | A novel human immunodeficiency virus ... | |
| 2000 | P Richard Harrigan, C Stone, P Griffin, I Nájera, Stuart Bloor, S Kemp, M Tisdale, Brendan A Larder | Resistance profile of the human immun... | |
| 1999 | M Madrid, A Jacobo-Molina, Jianping Ding, Edward Arnold | Major subdomain rearrangement in HIV-... | |
| 1999 | M E Arranz, J A Díaz, S T Ingate, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, S Vega | Synthesis and anti-HIV activity of 1,... | |
| 1999 | Andrew L Hopkins, Jingshan Ren, Hiromichi Tanaka, Masanori Baba, M Okamato, David I Stuart, David K Stammers | Design of MKC-442 (emivirine) analogu... | |
| 1999 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, David I Stuart, David K Stammers | Crystallographic analysis of the bind... | |
| 1999 | Neerja Kaushik, Kamalendra Singh, I Alluru, Mukund J Modak | Tyrosine 222, a member of the YXDD mo... | |
| 1999 | Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari | Molecular basis for the enantioselect... | |
| 1999 | Junxing Shi, J J McAtee, S Schlueter Wirtz, P Tharnish, A Juodawlkis, Dennis C Liotta, Raymond F Schinazi | Synthesis and biological evaluation o... | |
| 1999 | Thomas A Steitz | DNA polymerases: structural diversity... | |
| 1999 | Paul L Boyer, J Lisziewicz, F Lori, Stephen H Hughes | Analysis of amino insertion mutations... | |
| 1999 | L L Furge, F Peter Guengerich | Explanation of pre-steady-state kinet... | |
| 1999 | Yudong Quan, Dimitrios Motakis, R Buckheit, Z Q Xu, M T Flavin, Michael A. Parniak, Mark A. Wainberg | Sensitivity and resistance to (+)-cal... | |
| 1999 | Z Gu, Mark A. Wainberg, N Nguyen-Ba, L L'Heureux, J M de Muys, T L Bowlin, R F Rando | Mechanism of action and in vitro acti... | |
| 1999 | J M de Muys, H Gourdeau, N Nguyen-Ba, D L Taylor, P S Ahmed, T Mansour, C Locas, N Richard, Mark A. Wainberg, R F Rando | Anti-human immunodeficiency virus typ... | |
| 1999 | Brendan A Larder, Stuart Bloor, S D Kemp, Kurt Hertogs, R L Desmet, V Miller, M Sturmer, Schlomo Staszewski, Jingshan Ren, David K Stammers, David I Stuart, Rudi Pauwels | A family of insertion mutations betwe... | |
| 1999 | Yudong Quan, Liwei Rong, Chen Liang, Mark A. Wainberg | Reverse transcriptase inhibitors can ... | |
| 1999 | H Rübsamen-Waigmann, E Huguenel, A Shah, A Paessens, H J Ruoff, H von Briesen, A Immelmann, U Dietrich, Mark A. Wainberg | Resistance mutations selected in vivo... | |
| 1999 | S Cen, Yangxin Huang, A Khorchid, J L Darlix, Mark A. Wainberg, Lawrence Kleiman | The role of Pr55(gag) in the annealin... | |
| 1999 | G Borkow, Dominique Arion, Mark A. Wainberg, Michael A. Parniak | The thiocarboxanilide nonnucleoside i... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Arthur D Clark, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Lamivudine (3TC) resistance in HIV-1 ... | |
| 1999 | Lawrence A Loeb, J M Essigmann, F Kazazi, Jun Zhang, K D Rose, J I Mullins | Lethal mutagenesis of HIV with mutage... | |
| 1999 | P F Lin, C J González, B Griffith, G Friedland, V Calvez, F Ferchal, Raymond F Schinazi, D H Shepp, A B Ashraf, Mark A. Wainberg, V Soriano, John W Mellors, R J Colonno | Stavudine resistance: an update on su... | |
| 1999 | Katarzyna Bebenek, J C Boyer, Thomas A Kunkel | The base substitution fidelity of HIV... | |
| 1999 | M Wisniewski, C Palaniappan, Z Fu, Stuart F J Le Grice, P Fay, Robert A Bambara | Mutations in the primer grip region o... | |
| 1999 | M D Powell, William A Beard, Katarzyna Bebenek, K J Howard, Stuart F J Le Grice, Thomas A Darden, Thomas A Kunkel, Samuel H Wilson, J G Levin | Residues in the alphaH and alphaI hel... | |
| 1999 | Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | Action of a new mammalian DNA polymer... | |
| 1999 | Dominique Arion, Michael A. Parniak | HIV resistance to zidovudine: the rol... | |
| 1999 | Peter R Meyer, Suzanne E Matsuura, A M Mian, Antero G So, Walter A Scott | A mechanism of AZT resistance: an inc... | |
| 1999 | Matthias Götte, Xincang Li, Mark A. Wainberg | HIV-1 reverse transcription: a brief ... | |
| 1999 | Mark A. Wainberg, Michael D Miller, Yudong Quan, H Salomon, A S Mulato, P D Lamy, Nicolas A Margot, K E Anton, J M Cherrington | In vitro selection and characterizati... | |
| 1999 | N Richar, Yudong Quan, H Salomon, M Hsu, J Bedard, P Richard Harrigan, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg | Selection and characterization of HIV... | |
| 1999 | D A Lewis, Katarzyna Bebenek, William A Beard, Samuel H Wilson, Thomas A Kunkel | Uniquely altered DNA replication fide... | |
| 1999 | J Izopet, A Bicart-See, C Pasquier, K Sandres, E Bonnet, B Marchou, J Puel, P Massip | Mutations conferring resistance to zi... | |
| 1999 | I Pellegrin, J Izopet, J Reynes, M Denayrolles, Brigitte Montes, J L Pellegrin, P Massip, J Puel, H Fleury, Michel Segondy | Emergence of zidovudine and multidrug... | |
| 1999 | H Idriss, S Kawa, Z Damuni, E B Thompson, Samuel H Wilson | HIV-1 reverse transcriptase is phosph... | |
| 1999 | A Rakik, M Ait-Khaled, P Griffin, T A Thomas, M Tisdale, Jörg-Peter Kleim | A novel genotype encoding a single am... | |
| 1999 | Baek Kim, J C Ayran, S G Sagar, Elinor T Adman, S M Fuller, N H Tran, J Horrigan | New human immunodeficiency virus, typ... | |
| 1999 | Alexandra Vaisman, Susan E Lim, S M Patrick, William C Copeland, David C Hinkle, J J Turchi, Stephen G Chaney | Effect of DNA polymerases and high mo... | |
| 1999 | Zucai Suo, S J Lippard, Kenneth A Johnson | Single d(GpG)/cis-diammineplatinum(II... | |
| 1999 | Stefan G Sarafianos, Kalyan Das, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold | Touching the heart of HIV-1 drug resi... | |
| 1999 | Matthias Götte, G Maier, A M Onori, Luciano Cellai, Mark A. Wainberg, H Heumann | Temporal coordination between initiat... | |
| 1999 | Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes | Similarities and differences in the R... | |
| 1999 | Sylvie Doublié, M R Sawaya, Tom Ellenberger | An open and closed case for all polym... | |
| 1999 | Y Goldgur, R Craigie, G H Cohen, Tsuyoshi Fujiwara, T Yoshinaga, T Fujishita, H Sugimoto, T Endo, H Murai, D R Davies | Structure of the HIV-1 integrase cata... | |
| 1999 | T Szyperski, Matthias Götte, M Billeter, E Perola, Luciano Cellai, H Heumann, K Wüthrich | NMR structure of the chimeric hybrid ... | |
| 1999 | Jan Balzarini | Suppression of resistance to drugs ta... | |
| 1999 | J J de Jong, J Goudsmit, V V Lukashov, M E Hillebrand, E Baan, R Huismans, Sven A Danner, J H ten Veen, F de Wolf, Suzanne Jurriaans | Insertion of two amino acids combined... | |
| 1999 | Sonsoles Velázquez, V Tuñón, M L Jimeno, Cristina Chamorro, Erik De Clercq, Jan Balzarini, María-José Camarasa | Potential multifunctional inhibitors ... | |
| 1999 | Myriam Witvrouw, Christophe Pannecouque, Erik De Clercq, E Fernández-Alvarez, J L Marco | Inhibition of human immunodeficiency ... | |
| 1999 | Michael D Miller, K E Anton, A S Mulato, P D Lamy, J M Cherrington | Human immunodeficiency virus type 1 e... | |
| 1999 | Myriam Witvrouw, Christophe Pannecouque, Kristel Van Laethem, J Desmyter, Erik De Clercq, Anne-Mieke Vandamme | Activity of non-nucleoside reverse tr... | |
| 1999 | Taurai Tasara, Mario Amacker, Ulrich Hübscher | Intramolecular chimeras of the p51 su... | |
| 1999 | Andreas Marx, M Spichty, Mario Amacker, U Schwitter, Ulrich Hübscher, Thomas A Bickle, Giovanni Maga, Bernd Giese | Probing interactions between HIV-1 re... | |
| 1999 | Giuseppe Campiani, Elena Morelli, M Fabbrini, Vito Nacci, Giovanni Greco, Ettore Novellino, Anna Ramunno, Giovanni Maga, Silvio Spadari, G Caliendo, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, A Nacca, S Caccia | Pyrrolobenzoxazepinone derivatives as... | |
| 1999 | Joy Y Feng, Karen S Anderson | Mechanistic studies comparing the inc... | |
| 1999 | M Högberg, Christer Sahlberg, P Engelhardt, Rolf Noréen, J Kangasmetsä, N G Johansson, Bo Oberg, L Vrang, Haijiang Zhang, B L Sahlberg, Torsten Unge, S Lövgren, Kerstin Fridborg, K Bäckbro | Urea-PETT compounds as a new class of... | |
| 1998 | Tsuyoshi Fujiwara, Akira Sato, M el-Farrash, S Miki, K Abe, Y Isaka, M Kodama, Y Wu, L B Chen, H Harada, H Sugimoto, Masami Hatanaka, Y Hinuma | S-1153 inhibits replication of known ... | |
| 1998 | A Acel, B E Udashkin, Mark A. Wainberg, E A Faust | Efficient gap repair catalyzed in vit... | |
| 1998 | F J Palella, K M Delaney, A C Moorman, M O Loveless, J Fuhrer, G A Satten, D J Aschman, S D Holmberg | Declining morbidity and mortality amo... | |
| 1998 | C Tamalet, J Izopet, N Koch, J Fantini, N Yahi | Stable rearrangements of the beta3-be... | |
| 1998 | C Katlama, M A Valantin, S Matheron, A Coutellier, V Calvez, D Descamps, C Longuet, M Bonmarchand, R Tubiana, M De Sa, R Lancar, Henri Agut, F Brun-Vezinet, D Costagliola | Efficacy and tolerability of stavudin... | |
| 1998 | Akitsu Ogawa, Takashi Murate, Shunji Izuta, Masaharu Takemura, Kyoji Furuta, Jun'ichi Kobayashi, T Kamikawa, Y Nimura, Shonen Yoshida | Sulfated glycoglycerolipid from archa... | |
| 1998 | Zucai Suo, Kenneth A Johnson | Selective inhibition of HIV-1 reverse... | |
| 1998 | Zucai Suo, Kenneth A Johnson | DNA secondary structure effects on DN... | |
| 1998 | Monica E Hamburgh, William C Drosopoulos, Vinayaka R Prasad | The influence of 3TC-resistance mutat... | |
| 1998 | Jianping Ding, Kalyan Das, Y Hsiou, Stefan G Sarafianos, Arthur D Clark, A Jacobo-Molina, C Tantillo, Stephen H Hughes, Edward Arnold | Structure and functional implications... | |
| 1998 | Hao Huang, R Chopra, G L Verdine, S C Harrison | Structure of a covalently trapped cat... | |
| 1998 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, J Warren, Jan Balzarini, David I Stuart, David K Stammers | Crystal structures of HIV-1 reverse t... | |
| 1998 | Jingshan Ren, R M Esnouf, Andrew L Hopkins, E Yvonne Jones, I Kirby, J Keeling, C K Ross, Brendan A Larder, David I Stuart, David K Stammers | 3'-Azido-3'-deoxythymidine drug resis... | |
| 1998 | Joachim Jaeger, Tobias Restle, Thomas A Steitz | The structure of HIV-1 reverse transc... | |
| 1998 | Y Hsiou, Kalyan Das, Jianping Ding, Arthur D Clark, Jörg-Peter Kleim, M Rösner, I Winkler, G Riess, Stephen H Hughes, Edward Arnold | Structures of Tyr188Leu mutant and wi... | |
| 1998 | S W Graves, Allison A Johnson, Kenneth A Johnson | Expression, purification, and initial... | Processivity,Kd,Vmax,All properties |
| 1998 | Baek Kim, T R Hathaway, Lawrence A Loeb | Fidelity of mutant HIV-1 reverse tran... | |
| 1998 | D Harris, P N Yadav, V N Pandey | Loss of polymerase activity due to Ty... | |
| 1998 | D Harris, Neerja Kaushik, P K Pandey, P N Yadav, V N Pandey | Functional analysis of amino acid res... | |
| 1998 | Matthias Götte, G Maier, H J Gross, H Heumann | Localization of the active site of HI... | |
| 1998 | G Tachedjian, John W Mellors, H Bazmi, J Mills | Impaired fitness of foscarnet-resista... | |
| 1998 | Dominique Arion, Neerja Kaushik, Suzanne McCormick, G Borkow, Michael A. Parniak | Phenotypic mechanism of HIV-1 resista... | |
| 1998 | Bruno Canard, S R Sarfati, Charles C Richardson | Enhanced binding of azidothymidine-re... | |
| 1998 | Peter R Meyer, Suzanne E Matsuura, Antero G So, Walter A Scott | Unblocking of chain-terminated primer... | |
| 1998 | Joseph A Vaccaro, Karen S Anderson | Implication of the tRNA initiation st... | |
| 1998 | M A Winters, K L Coolley, Y A Girard, D J Levee, H Hamdan, R W Shafer, D A Katzenstein, T C Merigan | A 6-basepair insert in the reverse tr... | |
| 1998 | Michael D Miller, P D Lamy, M D Fuller, A S Mulato, Nicolas A Margot, T Cihlar, J M Cherrington | Human immunodeficiency virus type 1 r... | |
| 1998 | Mark Cushman, A Casimiro-Garcia, E Hejchman, J A Ruell, M Huang, C A Schaeffer, K Williamson, W G Rice, Robert W Buckheit | New alkenyldiarylmethanes with enhanc... | |
| 1998 | L M Demeter, P M Meehan, G Morse, M A Fischl, M Para, W Powderly, J Leedom, J Holden-Wiltse, C Greisberger, K Wood, J Timpone, L K Wathen, T Nevin, L Resnick, D H Batts, R C Reichman | Phase I study of atevirdine mesylate ... | |
| 1998 | Myriam Witvrouw, M E Arranz, Christophe Pannecouque, R Declercq, H Jonckheere, J C Schmit, A-M Vandamme, J A Diaz, S T Ingate, J Desmyter, Robert Esnouf, L Van Meervelt, S Vega, Jan Balzarini, Erik De Clercq | 1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,... | |
| 1998 | H Pelemans, R M Esnouf, Michael A. Parniak, A-M Vandamme, Erik De Clercq, Jan Balzarini | A proline-to-histidine substitution a... | |
| 1998 | H Togashi, Yoshiyuki Mizushina, Masaharu Takemura, Fumio Sugawara, Hiroyuki Koshino, Y Esumi, J Uzawa, H Kumagai, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | 4-Hydroxy-17-methylincisterol, an inh... | |
| 1998 | Yoshiyuki Mizushina, L Hanashima, Tsuyoshi Yamaguchi, Masaharu Takemura, Fumio Sugawara, Mineo Saneyoshi, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | A mushroom fruiting body-inducing sub... | |
| 1998 | Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi | Sulfoquinovosyldiacylglycerol, KM043,... | |
| 1998 | M Nakayabu, S Miwa, Motoshi Suzuki, Shunji Izuta, G Sobue, Shonen Yoshida | Mismatched nucleotides may facilitate... | |
| 1998 | H J Einolf, N Schnetz-Boutaud, F Peter Guengerich | Steady-state and pre-steady-state kin... | |
| 1998 | Silvio Spadari, Giovanni Maga, A Verri, Federico Focher | Molecular basis for the antiviral and... | |
| 1998 | William A Beard, Katarzyna Bebenek, Thomas A Darden, Lin Li, Rajendra Prasad, Thomas A Kunkel, Samuel H Wilson | Vertical-scanning mutagenesis of a cr... | |
| 1998 | I Choudhury, Jianhong Wang, A B Rabson, S Stein, S Pooyan, S Stein, M J Leibowitz | Inhibition of HIV-1 replication by a ... | |
| 1998 | Andreas Marx, Mario Amacker, M Stucki, Ulrich Hübscher, Thomas A Bickle, Bernd Giese | 4'-Acylated thymidine 5'-triphosphate... | |
| 1998 | M von Janta-Lipinski, B Costisella, H Ochs, Ulrich Hübscher, P Hafkemeyer, E Matthes | Newly synthesized L-enantiomers of 3'... | |
| 1998 | Mario Amacker, Ulrich Hübscher | Chimeric HIV-1 and feline immunodefic... | |
| 1998 | Hong Qiang Gao, Paul L Boyer, Edward Arnold, Stephen H Hughes | Effects of mutations in the polymeras... | |
| 1998 | D V Nissley, Paul L Boyer, D J Garfinkel, Stephen H Hughes, J N Strathern | Hybrid Ty1/HIV-1 elements used to det... | |
| 1998 | Paul L Boyer, Hong Qiang Gao, Stephen H Hughes | A mutation at position 190 of human i... | |
| 1998 | Yudong Quan, P Inouye, Chen Liang, Liwei Rong, Matthias Götte, Mark A. Wainberg | Dominance of the E89G substitution in... | |
| 1998 | H Salomon, Julio S G Montaner, A Belmonte, Mark A. Wainberg | Diminished HIV-1 sensitivity to stavu... | |
| 1998 | Yudong Quan, Chen Liang, P Inouye, Mark A. Wainberg | Enhanced impairment of chain elongati... | |
| 1998 | E Cherry, Chen Liang, Liwei Rong, Yudong Quan, P Inouye, Xincang Li, N Morin, M Kotler, Mark A. Wainberg | Characterization of human immunodefic... | |
| 1998 | William C Drosopoulos, Lisa F Rezende, Mark A. Wainberg, Vinayaka R Prasad | Virtues of being faithful: can we lim... | |
| 1998 | E Cherry, N Morin, Mark A. Wainberg | Effect of HIV constructs containing p... | |
| 1998 | P Inouye, E Cherry, M Hsu, S Zolla-Pazner, Mark A. Wainberg | Neutralizing antibodies directed agai... | |
| 1998 | Yudong Quan, Z Gu, Xincang Li, Chen Liang, Michael A. Parniak, Mark A. Wainberg | Endogenous reverse transcriptase assa... | |
| 1998 | H Kwon, N Pelletier, C DeLuca, P Genin, S Cisternas, R Lin, Mark A. Wainberg, J Hiscott | Inducible expression of IkappaBalpha ... | |
| 1998 | M Wasner, Dominique Arion, G Borkow, A Noronha, A H Uddin, Michael A. Parniak, Masad J Damha | Physicochemical and biochemical prope... | |
| 1998 | Cristina Chamorro, María-José Camarasa, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, Ana San Félix | An approach towards the synthesis of ... | |
| 1998 | Sonsoles Velázquez, Cristina Chamorro, María-Jesús Pérez-Pérez, R Alvarez, M L Jimeno, A Martín-Domenech, C Pérez, Federico Gago, Erik De Clercq, Jan Balzarini, Ana San-Félix, María-José Camarasa | Abasic analogues of TSAO-T as the fir... | |
| 1998 | Erik De Clercq | The role of non-nucleoside reverse tr... | |
| 1998 | J C Schmit, L Ruiz, L Stuyver, Kristel Van Laethem, I Vanderlinden, T Puig, R Rossau, J Desmyter, Erik De Clercq, B Clotet, A-M Vandamme | Comparison of the LiPA HIV-1 RT test,... | |
| 1998 | Erik De Clercq | New perspectives for the treatment of... | |
| 1998 | H Jonckheere, Myriam Witvrouw, Erik De Clercq, J Anné | Lamivudine resistance of HIV type 1 d... | |
| 1998 | Kamalendra Singh, Mukund J Modak | A unified DNA- and dNTP-binding mode ... | |
| 1997 | Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, Koen Andries, Robert W Buckheit, Richard H Smith | Molecular modeling of HIV-1 reverse t... | |
| 1997 | Robert W Buckheit, M J Snow, V Fliakas-Boltz, T L Kinjerski, J D Russell, L A Pallansch, W G Brouwer, S S Yang | Highly potent oxathiin carboxanilide ... | |
| 1997 | E Forgacs, G Latham, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd | Probing structure/function relationsh... | |
| 1997 | Myriam Witvrouw, Jan Balzarini, Christophe Pannecouque, S Jhaumeer-Laulloo, J A Esté, Dominique Schols, Peter Cherepanov, J C Schmit, Zeger Debyser, A-M Vandamme, J Desmyter, S R Ramadas, Erik De Clercq | SRR-SB3, a disulfide-containing macro... | |
| 1997 | Jianping Ding, Stephen H Hughes, Edward Arnold | Protein-nucleic acid interactions and... | |
| 1997 | H Pelemans, Robert Esnouf, A Dunkler, Michael A. Parniak, A-M Vandamme, Anna Karlsson, Erik De Clercq, Jörg-Peter Kleim, Jan Balzarini | Characteristics of the Pro225His muta... | |
| 1997 | Jörg-Peter Kleim, I Winkler, M Rösner, R Kirsch, H Rübsamen-Waigmann, A Paessens, G Riess | In vitro selection for different muta... | |
| 1997 | Stefano Aquaro, CF Perno, Emanuela Balestra, Jan Balzarini, A Cenci, M Francesconi, S Panti, F Serra, N Villani, Raffaele Caliò | Inhibition of replication of HIV in p... | |
| 1997 | Jan Balzarini, H Pelemans, G Riess, M Roesner, I Winkler, Erik De Clercq, Jörg-Peter Kleim | Zidovudine-resistant human immunodefi... | |
| 1997 | Erik De Clercq | Development of resistance of human im... | |
| 1997 | Erik De Clercq | In search of a selective antiviral ch... | |
| 1997 | M Tanaka, R V Srinivas, Takayuki Ueno, M F Kavlick, F K Hui, A Fridland, J S Driscoll, Hiroyuki Mitsuya | In vitro induction of human immunodef... | |
| 1997 | Yoshiyuki Mizushina, Shonen Yoshida, Akio Matsukage, Kengo Sakaguchi | The inhibitory action of fatty acids ... | |
| 1997 | L L Furge, F Peter Guengerich | Analysis of nucleotide insertion and ... | |
| 1997 | A De Antoni, A Foli, J Lisziewicz, F Lori | Mutations in the pol gene of human im... | |
| 1997 | Giovanni Maga, Mario Amacker, N Ruel, Ulrich Hübscher, Silvio Spadari | Resistance to nevirapine of HIV-1 rev... | |
| 1997 | I V Safronov, N V Shcherbik, Svetlana N Khodyreva, V A Vlasov, M I Dobrikov, G V Shishkin, Olga I Lavrik | [New photoreactive N(4)-substituted d... | |
| 1997 | Myriam Witvrouw, Erik De Clercq | Sulfated polysaccharides extracted fr... | |
| 1997 | H Hara, T Fujihashi, T Sakata, A Kaji, H Kaji | Tetrahydronaphthalene lignan compound... | |
| 1997 | B P Burnett, Charles S McHenry | Posttranscriptional modification of r... | |
| 1997 | Bruno Canard, R Sarfati, Charles C Richardson | Binding of RNA template to a complex ... | |
| 1997 | W Keulen, N K Back, A van Wijk, Charles A B Boucher, Ben Berkhout | Initial appearance of the 184Ile vari... | |
| 1997 | A Hizi, Ashwini S Kamath-Loeb, K D Rose, Lawrence A Loeb | Mutagenesis by human immunodeficiency... | |
| 1997 | Ashwini S Kamath-Loeb, A Hizi, Hironori Kasai, Lawrence A Loeb | Incorporation of the guanosine tripho... | |
| 1997 | G Borkow, Dominique Arion, A Noronha, M Scartozzi, Masad J Damha, Michael A. Parniak | Inhibitory potency of R-region specif... | |
| 1997 | M Hsu, P Inouye, L Rezende, N Richard, Zhongjie Li, Vinayaka R Prasad, Mark A. Wainberg | Higher fidelity of RNA-dependent DNA ... | |
| 1997 | Chen Liang, Liwei Rong, N Morin, E Cherry, Yangxin Huang, Lawrence Kleiman, Mark A. Wainberg | The roles of the human immunodeficien... | |
| 1997 | F Lori, A G Malykh, A Foli, R Maserati, A De Antoni, L Minoli, D Padrini, A Degli Antoni, E Barchi, H Jessen, Mark A. Wainberg, R C Gallo, J Lisziewicz | Combination of a drug targeting the c... | |
| 1997 | Chen Liang, Xincang Li, Liwei Rong, P Inouye, Yudong Quan, Lawrence Kleiman, Mark A. Wainberg | The importance of the A-rich loop in ... | |
| 1997 | Mark A. Wainberg | Increased fidelity of drug-selected M... | |
| 1997 | J Mak, A Khorchid, Q Cao, Yangxin Huang, I Lowy, Michael A. Parniak, Vinayaka R Prasad, Mark A. Wainberg, Lawrence Kleiman | Effects of mutations in Pr160gag-pol ... | |
| 1997 | M D Powell, M Ghosh, P S Jacques, K J Howard, Stuart F J Le Grice, J G Levin | Alanine-scanning mutations in the "pr... | |
| 1997 | C Palaniappan, M Wisniewski, P S Jacques, Stuart F J Le Grice, P J Fay, Robert A Bambara | Mutations within the primer grip regi... | |
| 1997 | Neerja Kaushik, D Harris, N Rege, Mukund J Modak, P N Yadav, V N Pandey | Role of glutamine-151 of human immuno... | |
| 1997 | G Gao, M Orlova, Millie M Georgiadis, W A Hendrickson, S P Goff | Conferring RNA polymerase activity to... | |
| 1997 | Jan Balzarini, Erik De Clercq, K Uberla | SIV/HIV-1 hybrid virus expressing the... | |
| 1997 | R M Esnouf, David I Stuart, Erik De Clercq, E Schwartz, Jan Balzarini | Models which explain the inhibition o... | |
| 1997 | J Barnard, G Borkow, Michael A. Parniak | The thiocarboxanilide nonnucleoside U... | |
| 1997 | M Tisdale, T Alnadaf, D Cousens | Combination of mutations in human imm... | |
| 1997 | Takayuki Ueno, Hiroyuki Mitsuya | Comparative enzymatic study of HIV-1 ... | |
| 1997 | T Rubinek, M Bakhanashvili, R Taube, O Avidan, A Hizi | The fidelity of 3' misinsertion and m... | |
| 1997 | S Loya, Hong Qiang Gao, O Avidan, Paul L Boyer, Stephen H Hughes, A Hizi | Subunit-specific mutagenesis of the c... | |
| 1997 | Y M Lin, H Anderson, M T Flavin, Y H Pai, E Mata-Greenwood, T Pengsuparp, J M Pezzuto, Raymond F Schinazi, Stephen H Hughes, F C Chen | In vitro anti-HIV activity of biflavo... | |
| 1997 | S G Kerr, Karen S Anderson | Pre-steady-state kinetic characteriza... | |
| 1997 | G Borkow, Ronald S Fletcher, J Barnard, Dominique Arion, Dimitrios Motakis, G I Dmitrienko, Michael A. Parniak | Inhibition of the ribonuclease H and ... | |
| 1997 | G Borkow, J Barnard, T M Nguyen, A Belmonte, Mark A. Wainberg, Michael A. Parniak | Chemical barriers to human immunodefi... | |
| 1997 | R Krebs, U Immendörfer, S H Thrall, B M Wöhrl, R S Goody | Single-step kinetics of HIV-1 reverse... | |
| 1997 | R M Esnouf, Jingshan Ren, Andrew L Hopkins, C K Ross, E Yvonne Jones, David K Stammers, David I Stuart | Unique features in the structure of t... | |
| 1997 | W Tong, C D Lu, S K Sharma, S Matsuura, Antero G So, Walter A Scott | Nucleotide-induced stable complex for... | |
| 1997 | Zucai Suo, Kenneth A Johnson | Effect of RNA secondary structure on ... | |
| 1997 | Zucai Suo, Kenneth A Johnson | RNA secondary structure switching dur... | |
| 1997 | Zucai Suo, Kenneth A Johnson | Effect of RNA secondary structure on ... | |
| 1997 | M A Winters, R W Shafer, R A Jellinger, G Mamtora, T Gingeras, T C Merigan | Human immunodeficiency virus type 1 r... | |
| 1997 | Mario Amacker, M Hottiger, R Mossi, Ulrich Hübscher | HIV-1 nucleocapsid protein and replic... | |
| 1997 | Thomas Roth, Marshall L Morningstar, Paul L Boyer, Stephen H Hughes, Robert W Buckheit, Christopher J Michejda | Synthesis and biological activity of ... | |
| 1996 | T Pengsuparp, M Serit, Stephen H Hughes, D D Soejarto, J M Pezzuto | Specific inhibition of human immunode... | |
| 1996 | Zeger Debyser, Erik De Clercq | Chemical crosslinking of the subunits... | |
| 1996 | Rudi Pauwels, Erik De Clercq | Development of vaginal microbicides f... | |
| 1996 | M G Davis, J E Wilson, N A VanDraanen, W H Miller, George A Freeman, S M Daluge, F L Boyd, A E Aulabaugh, George R Painter, Lawrence R Boone | DNA polymerase activity of hepatitis ... | |
| 1996 | B M Moore, Ke Li, Michael B Doughty | Deoxyadenosine-based DNA polymerase p... | |
| 1996 | Mark A. Wainberg, M Hsu, Z Gu, G Borkow, Michael A. Parniak | Effectiveness of 3TC in HIV clinical ... | |
| 1996 | Zhongjie Li, A Shalom, Yangxin Huang, J Mak, E Arts, Mark A. Wainberg, Lawrence Kleiman | Multiple forms of tRNA(Lys3) in HIV-1. | |
| 1996 | Dominique Arion, R Harada, Xincang Li, Mark A. Wainberg, Michael A. Parniak | HIV-1 reverse transcriptase shows no ... | |
| 1996 | Neerja Kaushik, N Rege, P N Yadav, Stefan G Sarafianos, Mukund J Modak, V N Pandey | Biochemical analysis of catalytically... | |
| 1996 | Jörg-Peter Kleim, M Rösner, I Winkler, A Paessens, R Kirsch, Y Hsiou, Edward Arnold, G Riess | Selective pressure of a quinoxaline n... | |
| 1996 | M Hottiger, Ulrich Hübscher | Human Immunodeficiency Virus type 1 r... | |
| 1996 | D L Winslow, S Garber, C Reid, H Scarnati, D Baker, M M Rayner, E D Anton | Selection conditions affect the evolu... | |
| 1996 | Jan Balzarini, W G Brouwer, D C Dao, E M Osika, Erik De Clercq | Identification of novel thiocarboxani... | |
| 1996 | Xincang Li, Yudong Quan, E.J. Arts, Zhongjie Li, Bradley D Preston, H de Rocquigny, Bernard P Roques, J L Darlix, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg | Human immunodeficiency virus Type 1 n... | |
| 1996 | J M Cherrington, M D Fuller, A S Mulato, S J Allen, S C Kunder, M A Ussery, Z Lesnikowski, Raymond F Schinazi, J P Sommadossi, M S Chen | Comparative kinetic analyses of inter... | |
| 1996 | D Bellarosa, G Antonelli, F Bambacioni, D Giannotti, G Viti, R Nannicini, A Giachetti, F Dianzani, Myriam Witvrouw, Rudi Pauwels, J Desmyter, Erik De Clercq | New arylpyrido-diazepine and -thiodia... | |
| 1996 | Dominique Arion, Ronald S Fletcher, G Borkow, María-José Camarasa, Jan Balzarini, G I Dmitrienko, Michael A. Parniak | Differences in the inhibition of huma... | |
| 1996 | H Jonckheere, K De Vreese, Zeger Debyser, J Vandekerckhove, Jan Balzarini, J Desmyter, Erik De Clercq, J Anné | A two plasmid co-expression system in... | |
| 1996 | S Ingate, Erik De Clercq, Jan Balzarini, María-José Camarasa | Novel L-lyxo and 5'-deoxy-5'-modified... | |
| 1996 | William A Beard, Dana T Minnick, C L Wade, Rajendra Prasad, R L Won, A Kumar, Thomas A Kunkel, Samuel H Wilson | Role of the "helix clamp" in HIV-1 re... | |
| 1996 | Mark A. Wainberg, L Lewis, H Salomon, Z Gu, A Keller, Nick Cammack, J Goldsmith, J Church, Bonnie Spira, S Wheeler, P Pizzo | Resistance to (-)-2',3'-dideoxy-3'-th... | |
| 1996 | Z Gu, Xincang Li, Yudong Quan, Michael A. Parniak, Mark A. Wainberg | Studies of neutralizing monoclonal an... | |
| 1996 | Mark A. Wainberg, William C Drosopoulos, H Salomon, M Hsu, G Borkow, M Parniak, Z Gu, Q Song, J Manne, S Islam, G Castriota, Vinayaka R Prasad | Enhanced fidelity of 3TC-selected mut... | |
| 1996 | Ronald S Fletcher, G Holleschak, Eva Nagy, Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak | Single-step purification of recombina... | |
| 1996 | E.J. Arts, J P Marois, Z Gu, Stuart F J Le Grice, Mark A. Wainberg | Effects of 3'-deoxynucleoside 5'-trip... | |
| 1996 | Jan Balzarini, O Wedgwood, J Kruining, H Pelemans, R Heijtink, Erik De Clercq, Christopher McGuigan | Anti-HIV and anti-HBV activity and re... | |
| 1996 | Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak | The K65R mutation confers increased D... | RT,Cloned or native,Full length or truncated,Extension from RNA primer,All properties |
| 1996 | L Hong, A Treharne, J A Hartsuck, S Foundling, J Tang | Crystal structures of complexes of a ... | |
| 1996 | M Evers, C Poujade, F Soler, Y Ribeill, C James, Y Lelièvre, J C Gueguen, D Reisdorf, I Morize, Rudi Pauwels, Erik De Clercq, Y Hénin, Anne Bousseau, J F Mayaux, J B Le Pecq, N Dereu | Betulinic acid derivatives: a new cla... | |
| 1996 | F Soler, C Poujade, M Evers, J C Carry, Y Hénin, Anne Bousseau, T Huet, Rudi Pauwels, Erik De Clercq, J F Mayaux, J B Le Pecq, N Dereu | Betulinic acid derivatives: a new cla... | |
| 1996 | L M Mansky | Forward mutation rate of human immuno... | |
| 1996 | Jan Balzarini, H Pelemans, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson | Marked inhibitory activity of non-nuc... | |
| 1996 | J E Wilson, A Aulabaugh, B Caligan, S McPherson, J K Wakefield, S Jablonski, C D Morrow, J E Reardon, Phillip A Furman | Human immunodeficiency virus type-1 r... | |
| 1996 | Baek Kim, T R Hathaway, Lawrence A Loeb | Human immunodeficiency virus reverse ... | |
| 1996 | J Ji, N J Clegg, K R Peterson, A L Jackson, C D Laird, Lawrence A Loeb | In vitro expansion of GGC:GCC repeats... | |
| 1996 | CF Perno, Emanuela Balestra, Stefano Aquaro, S Panti, A Cenci, G Lazzarino, B Tavazzi, D Di Pierro, Jan Balzarini, R Calio | Potent inhibition of human immunodefi... | |
| 1996 | J A Esté, K De Vreese, Myriam Witvrouw, J C Schmit, A-M Vandamme, J Anné, J Desmyter, G W Henson, G Bridger, Erik De Clercq | Antiviral activity of the bicyclam de... | |
| 1996 | Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Stephen H Hughes, Edward Arnold | Structure of unliganded HIV-1 reverse... | |
| 1996 | D J Hooker, G Tachedjian, A E Solomon, A D Gurusinghe, S Land, C Birch, J L Anderson, B M Roy, Edward Arnold, N J Deacon | An in vivo mutation from leucine to t... | |
| 1996 | V N Pandey, Neerja Kaushik, N Rege, Stefan G Sarafianos, P N Yadav, Mukund J Modak | Role of methionine 184 of human immun... | |
| 1996 | N K Back, Monique Nijhuis, W Keulen, Charles A B Boucher, B O Oude Essink, A B van Kuilenburg, A H van Gennip, Ben Berkhout | Reduced replication of 3TC-resistant ... | |
| 1996 | R A Olmsted, D E Slade, L A Kopta, S M Poppe, T J Poel, S W Newport, K B Rank, C Biles, R A Morge, T J Dueweke, Y Yagi, D L Romero, R C Thomas, S K Sharma, W G Tarpley | (Alkylamino) piperidine bis(heteroary... | |
| 1996 | Edward Arnold, Kalyan Das, Jianping Ding, P N Yadav, Y Hsiou, Paul L Boyer, Stephen H Hughes | Targeting HIV reverse transcriptase f... | |
| 1996 | A Foli, K M Sogocio, B Anderson, M Kavlick, M W Saville, Mark A. Wainberg, Z Gu, J M Cherrington, Hiroyuki Mitsuya, R Yarchoan | In vitro selection and molecular char... | |
| 1996 | G Yang, Q Song, M Charles, William C Drosopoulos, Edward Arnold, Vinayaka R Prasad | Use of chimeric human immunodeficienc... | |
| 1996 | H D Sun, S X Qiu, L Z Lin, Z Y Wang, Z W Lin, T Pengsuparp, J M Pezzuto, H H Fong, G A Cordell, N R Farnsworth | Nigranoic acid, a triterpenoid from S... | |
| 1996 | Andrew L Hopkins, Jingshan Ren, R M Esnouf, B E Willcox, E Yvonne Jones, C Ross, T Miyasaka, R T Walker, Hiromichi Tanaka, David K Stammers, David I Stuart | Complexes of HIV-1 reverse transcript... | |
| 1996 | P Richard Harrigan, I Kinghorn, Stuart Bloor, S D Kemp, I Nájera, A Kohli, Brendan A Larder | Significance of amino acid variation ... | |
| 1996 | A M Martín-Hernández, Esteban Domingo, L Menéndez-Arias | Human immunodeficiency virus type 1 r... | |
| 1996 | Yudong Quan, Z Gu, Xincang Li, Zhongjie Li, C D Morrow, Mark A. Wainberg | Endogenous reverse transcription assa... | |
| 1996 | A K Iversen, R W Shafer, K Wehrly, M A Winters, J I Mullins, B Chesebro, T C Merigan | Multidrug-resistant human immunodefic... | |
| 1996 | Olga I Lavrik, Rajendra Prasad, William A Beard, I V Safronov, M I Dobrikov, Deepak K Srivastava, G V Shishkin, T G Wood, Samuel H Wilson | dNTP binding to HIV-1 reverse transcr... | |
| 1996 | J M Cherrington, A S Mulato, M D Fuller, M S Chen | Novel mutation (K70E) in human immuno... | |
| 1996 | R A Spence, Karen S Anderson, Kenneth A Johnson | HIV-1 reverse transcriptase resistanc... | |
| 1996 | G Tachedjian, J Mellors, H Bazmi, C Birch, J Mills | Zidovudine resistance is suppressed b... | |
| 1996 | William C Drosopoulos, Vinayaka R Prasad | Increased polymerase fidelity of E89G... | |
| 1996 | Yangxin Huang, A Shalom, Zhongjie Li, Jiong Wang, J Mak, Mark A. Wainberg, Lawrence Kleiman | Effects of modifying the tRNA(3Lys) a... | |
| 1996 | Kalyan Das, Jianping Ding, Y Hsiou, Arthur D Clark, H Moereels, Luc Koymans, Koen Andries, Rudi Pauwels, Paul A J Janssen, Paul L Boyer, Patrick K Clark, Richard H Smith, Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Edward Arnold | Crystal structures of 8-Cl and 9-Cl T... | |
| 1996 | Stefan G Sarafianos, U Kortz, M T Pope, Mukund J Modak | Mechanism of polyoxometalate-mediated... | |
| 1996 | Charles A B Boucher, W Keulen, T van Bommel, Monique Nijhuis, D de Jong, M D de Jong, P Schipper, N K Back | Human immunodeficiency virus type 1 d... | |
| 1996 | Michael J Lutz, H A Held, M Hottiger, Ulrich Hübscher, Steven A Benner | Differential discrimination of DNA po... | |
| 1996 | Erik De Clercq | Chemotherapy of human immunodeficienc... | |
| 1995 | Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak | Glutamine 151 participates in the sub... | |
| 1995 | Jan Balzarini | Novel concepts in the treatment of hu... | |
| 1995 | D W Rodgers, S J Gamblin, B A Harris, S Ray, J S Culp, B Hellmig, D J Woolf, C Debouck, S C Harrison | The structure of unliganded reverse t... | |
| 1995 | Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak | Site-directed mutagenesis of arginine... | |
| 1995 | Y Törnevik, B Ullman, Jan Balzarini, B Wahren, Staffan Eriksson | Cytotoxicity of 3'-azido-3'-deoxythym... | |
| 1995 | M Sala, S Wain-Hobson, F Schaeffer | Human immunodeficiency virus type 1 r... | |
| 1995 | L M Mansky, H M Temin | Lower in vivo mutation rate of human ... | |
| 1995 | P N Yadav, J S Yadav, Mukund J Modak | Nucleoside drug resistance in HIV-1 r... | |
| 1995 | N M Gray, C L Marr, C R Penn, J M Cameron, R C Bethell | The intracellular phosphorylation of ... | |
| 1995 | R A Spence, W M Kati, Karen S Anderson, Kenneth A Johnson | Mechanism of inhibition of HIV-1 reve... | |
| 1995 | R R Vyas, A K Basu | DNA polymerase action on an oligonucl... | |
| 1995 | Baek Kim, Lawrence A Loeb | Human immunodeficiency virus reverse ... | |
| 1995 | Z Gu, Yudong Quan, Zhongjie Li, E.J. Arts, Mark A. Wainberg | Effects of non-nucleoside inhibitors ... | |
| 1995 | M I Anazodo, H Salomon, A D Friesen, Mark A. Wainberg, J A Wright | Antiviral activity and protection of ... | |
| 1995 | E.J. Arts, Zhongjie Li, Mark A. Wainberg | Analysis of Primer Extension and the ... | |
| 1995 | V McKiel, Z Gu, Mark A. Wainberg, J Hiscott | Inhibition of human immunodeficiency ... | |
| 1995 | Ronald S Fletcher, Dominique Arion, G Borkow, Mark A. Wainberg, G I Dmitrienko, Michael A. Parniak | Synergistic inhibition of HIV-1 rever... | |
| 1995 | Mark A. Wainberg, Z Gu | Targeting HIV reverse transcriptase i... | |
| 1995 | R J Germinario, T DeSantis, Mark A. Wainberg | Insulin-like growth factor 1 and insu... | |
| 1995 | Z Gu, E.J. Arts, Michael A. Parniak, Mark A. Wainberg | Mutated K65R recombinant reverse tran... | |
| 1995 | M I Anazodo, Mark A. Wainberg, A D Friesen, J A Wright | Sequence-specific inhibition of gene ... | |
| 1995 | Mark A. Wainberg, Z Gu, H Salomon, E.J. Arts, Lawrence Kleiman, Michael A. Parniak, N Morin | [Molecular basis and clinical signifi... | |
| 1995 | M Ghosh, K J Howard, Craig E Cameron, Stephen J Benkovic, Stephen H Hughes, Stuart F J Le Grice | Truncating alpha-helix E' of p66 huma... | |
| 1995 | T Shirasaka, M F Kavlick, Takayuki Ueno, W Y Gao, E Kojima, M L Alcaide, S Chokekijchai, B M Roy, Edward Arnold, R Yarchoan | Emergence of human immunodeficiency v... | |
| 1995 | Brendan A Larder, S D Kemp, P Richard Harrigan | Potential mechanism for sustained ant... | |
| 1995 | Rob Schuurman, Monique Nijhuis, R van Leeuwen, P Schipper, D de Jong, P Collis, Sven A Danner, J Mulder, C Loveday, C Christopherson | Rapid changes in human immunodeficien... | |
| 1995 | K Rittinger, G Divita, R S Goody | Human immunodeficiency virus reverse ... | |
| 1995 | Matthias Götte, S Fackler, T Hermann, E Perola, Luciano Cellai, H J Gross, Stuart F J Le Grice, H Heumann | HIV-1 reverse transcriptase-associate... | |
| 1995 | Ronald S Fletcher, K Syed, S Mithani, G I Dmitrienko, Michael A. Parniak | Carboxanilide derivative non-nucleosi... | |
| 1995 | M Jaju, William A Beard, Samuel H Wilson | Human immunodeficiency virus type 1 r... | |
| 1995 | Hongxing Zhang, Yang Zhang, T Spicer, D Henrard, B J Poiesz | Nascent human immunodeficiency virus ... | |
| 1995 | Silvio Spadari, Giovanni Maga, A Verri, A Bendiscioli, L Tondelli, M Capobianco, F Colonna, A Garbesi, Federico Focher | Lack of stereospecificity of some cel... | |
| 1995 | Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari | Stereospecificity of human DNA polyme... | |
| 1995 | Baek Kim, Lawrence A Loeb | A screen in Escherichia coli for nucl... | |
| 1995 | Edward Arnold, Jianping Ding, Stephen H Hughes, Z Hostomsky | Structures of DNA and RNA polymerases... | |
| 1995 | Katarzyna Bebenek, William A Beard, J R Casas-Finet, H R Kim, Thomas A Darden, Samuel H Wilson, Thomas A Kunkel | Reduced frameshift fidelity and proce... | |
| 1995 | B M Wöhrl, C Tantillo, Edward Arnold, Stuart F J Le Grice | An expanded model of replicating huma... | |
| 1995 | P H Patel, A Jacobo-Molina, Jianping Ding, C Tantillo, Art D Clark, R Raag, R G Nanni, Stephen H Hughes, Edward Arnold | Insights into DNA polymerization mech... | |
| 1995 | Jörg-Peter Kleim, R Bender, R Kirsch, C Meichsner, A Paessens, M Rösner, H Rübsamen-Waigmann, R Kaiser, M Wichers, K E Schneweis | Preclinical evaluation of HBY 097, a ... | |
| 1995 | Marilyn B Kroeger Smith, C A Rouzer, L A Taneyhill, N A Smith, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, H Moereels, Luc Koymans, Edward Arnold | Molecular modeling studies of HIV-1 r... | |
| 1995 | Robert W Buckheit, V Fliakas-Boltz, S Yeagy-Bargo, O Weislow, D L Mayers, Paul L Boyer, Stephen H Hughes, B C Pan, S H Chu, J P Bader | Resistance to 1-[(2-hydroxyethoxy)met... | |
| 1995 | Haijiang Zhang, L Vrang, K Bäckbro, P Lind, Christer Sahlberg, Torsten Unge, Bo Oberg | Inhibition of human immunodeficiency ... | |
| 1995 | Robert W Buckheit, T L Kinjerski, V Fliakas-Boltz, J D Russell, T L Stup, L A Pallansch, W G Brouwer, D C Dao, W A Harrison, R J Schultz | Structure-activity and cross-resistan... | |
| 1995 | Jan Balzarini, María-Jesús Pérez-Pérez, S Vélazquez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson | Suppression of the breakthrough of hu... | |
| 1995 | M Hottiger, K Gramatikoff, O Georgiev, C Chaponnier, W Schaffner, Ulrich Hübscher | The large subunit of HIV-1 reverse tr... | |
| 1995 | J Horlacher, M Hottiger, Vladimir N Podust, Ulrich Hübscher, Steven A Benner | Recognition by viral and cellular DNA... | |
| 1995 | S D Young, S F Britcher, L O Tran, L S Payne, W C Lumma, T A Lyle, J R Huff, P S Anderson, David B Olsen, Steven S Carroll | L-743, 726 (DMP-266): a novel, highly... | |
| 1995 | Katarzyna Bebenek, Thomas A Kunkel | Analyzing fidelity of DNA polymerases. | Frameshift Error Rate,Overall Error Rate,All properties |
| 1995 | G Tachedjian, D J Hooker, A D Gurusinghe, H Bazmi, N J Deacon, J Mellors, C Birch, J Mills | Characterisation of foscarnet-resista... | |
| 1995 | Takayuki Ueno, T Shirasaka, Hiroyuki Mitsuya | Enzymatic characterization of human i... | |
| 1995 | John W Mellors, Holly Z Bazmi, Raymond F Schinazi, B M Roy, Y Hsiou, Edward Arnold, J Weir, D L Mayers | Novel mutations in reverse transcript... | |
| 1995 | Jingshan Ren, R Esnouf, E Garman, D Somers, C Ross, I Kirby, J Keeling, G Darby, Y Jones, David I Stuart | High resolution structures of HIV-1 R... | |
| 1995 | Jianping Ding, Kalyan Das, H Moereels, Luc Koymans, Koen Andries, Paul A J Janssen, Stephen H Hughes, Edward Arnold | Structure of HIV-1 RT/TIBO R 86183 co... | |
| 1995 | R Esnouf, Jingshan Ren, C Ross, Y Jones, D Stammers, David I Stuart | Mechanism of inhibition of HIV-1 reve... | |
| 1995 | Jingshan Ren, R Esnouf, A Hopkins, C Ross, Y Jones, D Stammers, David I Stuart | The structure of HIV-1 reverse transc... | |
| 1995 | Jianping Ding, Kalyan Das, C Tantillo, Weiming Zhang, Arthur D Clark, S Jessen, Xiaoqing Lu, Y Hsiou, A Jacobo-Molina, Koen Andries | Structure of HIV-1 reverse transcript... | |
| 1995 | Erik De Clercq, Jan Balzarini | Knocking out human immunodeficiency v... | |
| 1995 | Jan Balzarini, M Weeger, María-José Camarasa, Erik De Clercq, K Uberla | Sensitivity/resistance profile of a s... | |
| 1995 | Jan Balzarini, W G Brouwer, E E Felauer, Erik De Clercq, Anna Karlsson | Activity of various thiocarboxanilide... | |
| 1995 | Sonsoles Velázquez, R Alvarez, Ana San-Félix, M L Jimeno, Erik De Clercq, Jan Balzarini, María-José Camarasa | Synthesis and anti-HIV activity of [A... | |
| 1995 | Jan Balzarini, Masanori Baba, Erik De Clercq | Differential activities of 1-[(2-hydr... | |
| 1994 | Jan Balzarini, Anna Karlsson, C Meichsner, A Paessens, G Riess, Erik De Clercq, Jörg-Peter Kleim | Resistance pattern of human immunodef... | |
| 1994 | Torsten Unge, S Knight, R Bhikhabhai, S Lövgren, Z Dauter, K Wilson, B Strandberg | 2.2 A resolution structure of the ami... | |
| 1994 | Jianping Ding, A Jacobo-Molina, C Tantillo, Xiaoqing Lu, R G Nanni, Edward Arnold | Buried surface analysis of HIV-1 reve... | |
| 1994 | S F Lacey, Brendan A Larder | Novel mutation (V75T) in human immuno... | |
| 1994 | T Hermann, T Meier, Matthias Götte, H Heumann | The 'helix clamp' in HIV-1 reverse tr... | |
| 1994 | Rudi Pauwels, Koen Andries, Zeger Debyser, Michael J Kukla, Dominique Schols, H J Breslin, R Woestenborghs, J Desmyter, M A Janssen, Erik De Clercq | New tetrahydroimidazo[4,5,1-jk][1,4]-... | |
| 1994 | P S Jacques, B M Wöhrl, M Ottmann, J L Darlix, Stuart F J Le Grice | Mutating the "primer grip" of p66 HIV... | |
| 1994 | Erik De Clercq | How to overcome resistance of HIV-1 t... | |
| 1994 | Erik De Clercq | New developments in the chemotherapy ... | |
| 1994 | Masanori Baba, S Shigeta, S Yuasa, H Takashima, K Sekiya, M Ubasawa, Hiromichi Tanaka, T Miyasaka, R T Walker, Erik De Clercq | Preclinical evaluation of MKC-442, a ... | |
| 1994 | Erik De Clercq | HIV resistance to reverse transcripta... | |
| 1994 | J Mak, M Jiang, Mark A. Wainberg, M L Hammarskjöld, D Rekosh, Lawrence Kleiman | Role of Pr160gag-pol in mediating the... | |
| 1994 | Z Gu, Q Gao, H Fang, Michael A. Parniak, Bluma G Brenner, Mark A. Wainberg | Identification of novel mutations tha... | |
| 1994 | S Zinnen, J C Hsieh, P Modrich | Misincorporation and mispaired primer... | |
| 1994 | E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg | Mature reverse transcriptase (p66/p51... | |
| 1994 | Paul L Boyer, C Tantillo, A Jacobo-Molina, R G Nanni, Jianping Ding, Edward Arnold, Stephen H Hughes | Sensitivity of wild-type human immuno... | |
| 1994 | L Mercure, B J Brenner, D Phaneuf, C Tsoukas, Mark A. Wainberg | Effect of 3'-azido-3'-deoxythymidine ... | |
| 1994 | E.J. Arts, Xincang Li, Z Gu, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg | Comparison of deoxyoligonucleotide an... | |
| 1994 | S J Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, A J Chirino, J M Friedman, P A Rice, Thomas A Steitz | Structure of the binding site for non... | |
| 1994 | V W Byrnes, E A Emini, W A Schleif, J H Condra, C L Schneider, W J Long, J A Wolfgang, D J Graham, L Gotlib, A J Schlabach | Susceptibilities of human immunodefic... | |
| 1994 | M Smith, H Salomon, Mark A. Wainberg | Development and significance of nucle... | |
| 1994 | E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg | DNA found in human immunodeficiency v... | |
| 1994 | Z Gu, Ronald S Fletcher, E.J. Arts, Mark A. Wainberg, Michael A. Parniak | The K65R mutant reverse transcriptase... | |
| 1994 | P N Yadav, J S Yadav, Edward Arnold, Mukund J Modak | A computer-assisted analysis of conse... | |
| 1994 | M R Sawaya, H Pelletier, A Kumar, Samuel H Wilson, J Kraut | Crystal structure of rat DNA polymera... | |
| 1994 | Jan Balzarini, Jörg-Peter Kleim, G Riess, María-José Camarasa, Erik De Clercq, Anna Karlsson | Sensitivity of (138 Glu-->Lys) mutate... | |
| 1994 | J Ji, Lawrence A Loeb | Fidelity of HIV-1 reverse transcripta... | |
| 1994 | H Jonckheere, J M Taymans, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, J Desmyter, Erik De Clercq, J Anné | Resistance of HIV-1 reverse transcrip... | |
| 1994 | M H Nguyen, Raymond F Schinazi, C Shi, N M Goudgaon, P M McKenna, John W Mellors | Resistance of human immunodeficiency ... | |
| 1994 | A-M Vandamme, Zeger Debyser, Rudi Pauwels, K De Vreese, P Goubau, M Youle, B Gazzard, P A Stoffels, G F Cauwenbergh, J Anne | Characterization of HIV-1 strains iso... | |
| 1994 | S Loya, M Bakhanashvili, R Tal, Stephen H Hughes, Paul L Boyer, A Hizi | Enzymatic properties of two mutants o... | |
| 1994 | Jan Balzarini, Anna Karlsson, V V Sardana, E A Emini, María-José Camarasa, Erik De Clercq | Human immunodeficiency virus 1 (HIV-1... | |
| 1994 | G Gosselin, Raymond F Schinazi, J P Sommadossi, C Mathé, M C Bergogne, A M Aubertin, A Kirn, J L Imbach | Anti-human immunodeficiency virus act... | |
| 1994 | Myron F Goodman, H Cai, Linda B Bloom, R Eritja | Nucleotide insertion and primer exten... | |
| 1994 | Paul L Boyer, Andrea L Ferris, Patrick K Clark, J Whitmer, P Frank, C Tantillo, Edward Arnold, Stephen H Hughes | Mutational analysis of the fingers an... | |
| 1994 | J Ji, Jean-Sébastien Hoffmann, L Loeb | Mutagenicity and pausing of HIV rever... | |
| 1994 | I Kang, Jing-Houng Wang | Design of structure-based reverse tra... | |
| 1994 | C Tantillo, Jianping Ding, A Jacobo-Molina, R G Nanni, Paul L Boyer, Stephen H Hughes, Rudi Pauwels, Koen Andries, Paul A J Janssen, Edward Arnold | Locations of anti-AIDS drug binding s... | |
| 1994 | M Hottiger, Vladimir N Podust, R L Thimmig, C McHenry, Ulrich Hübscher | Strand displacement activity of the h... | |
| 1994 | William A Beard, Samuel H Wilson | Site-directed mutagenesis of HIV reve... | |
| 1994 | Douglas D Richman, D Havlir, J Corbeil, D Looney, C Ignacio, S A Spector, J Sullivan, S Cheeseman, K Barringer, D Pauletti | Nevirapine resistance mutations of hu... | |
| 1994 | H Pelletier, M R Sawaya, A Kumar, Samuel H Wilson, J Kraut | Structures of ternary complexes of ra... | |
| 1994 | M D Delahunty, Samuel H Wilson, R L Karpel | Studies on primer binding of HIV-1 re... | |
| 1994 | M A Fisher, P N Yadav, J Yadav, D Kristol, Edward Arnold, Mukund J Modak | Identification of a pharmacophore for... | |
| 1994 | T Rubinek, S Loya, M Shaharabany, Stephen H Hughes, Patrick K Clark, A Hizi | The catalytic properties of the rever... | |
| 1994 | S V Doronin, M I Dobrikov, M Buckle, P Roux, H Buc, Olga I Lavrik | Affinity modification of human immuno... | |
| 1994 | J Jäger, S J Smerdon, Jianhong Wang, D C Boisvert, Thomas A Steitz | Comparison of three different crystal... | |
| 1994 | A Okruszek, M Olesiak, Jan Balzarini | The synthesis of nucleoside 5'-O-(1,1... | |
| 1994 | Paul L Boyer, Jianping Ding, Edward Arnold, Stephen H Hughes | Subunit specificity of mutations that... | |
| 1993 | G T Tan, A Wickramasinghe, S Verma, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan | Sulfonic acid polymers are potent inh... | |
| 1993 | A Hizi, R Tal, M Shaharabany, M J Currens, M R Boyd, Stephen H Hughes, James B McMahon | Specific inhibition of the reverse tr... | |
| 1993 | R L Thimmig, Charles S McHenry | Human immunodeficiency virus reverse ... | |
| 1993 | H Cai, Linda B Bloom, R Eritja, Myron F Goodman | Kinetics of deoxyribonucleotide inser... | |
| 1993 | S St Luce, E Arts, R Geleziunas, S Bour, Mark A. Wainberg | Infection of human monocyte-derived m... | |
| 1993 | Xincang Li, E Amandoron, Mark A. Wainberg, Michael A. Parniak | Generation and characterization of mu... | |
| 1993 | Mark A. Wainberg, H Salomon, Bonnie Spira, L Mercure, J Wainberg, K Nagai, Z Bentwich, J Montaner | HIV resistance to anti-viral drugs. | |
| 1993 | Mark A. Wainberg, Z Gu, Q Gao, E Arts, R Geleziunas, S Bour, R Beaulieu, C Tsoukas, J Singer, J Montaner | Clinical correlates and molecular bas... | |
| 1993 | R Goel, William A Beard, A Kumar, J R Casas-Finet, M P Strub, S J Stahl, M S Lewis, Katarzyna Bebenek, S P Becerra, Thomas A Kunkel | Structure/function studies of HIV-1(1... | |
| 1993 | J Abbotts, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson | Mechanism of HIV-1 reverse transcript... | |
| 1993 | Katarzyna Bebenek, J Abbotts, Samuel H Wilson, Thomas A Kunkel | Error-prone polymerization by HIV-1 r... | |
| 1993 | S P Becerra, A Kumar, Samuel H Wilson | Expression of polypeptides of human i... | |
| 1993 | A Kumar, H R Kim, Robert W Sobol, S P Becerra, B J Lee, D L Hatfield, R J Suhadolnik, Samuel H Wilson | Mapping of nucleic acid binding in pr... | |
| 1993 | William A Beard, Samuel H Wilson | Kinetic analysis of template.primer i... | |
| 1993 | Robert W Sobol, W L Fisher, N L Reichenbach, A Kumar, William A Beard, Samuel H Wilson, R Charubala, W Pfleiderer, R J Suhadolnik | HIV-1 reverse transcriptase: inhibiti... | |
| 1993 | C T Wang, Yongqing Zhang, J McDermott, E Barklis | Conditional infectivity of a human im... | |
| 1993 | Svetlana N Khodyreva, Vladimir N Podust, D S Sergeev, E M Ivanova, E I Frolova, A A Koshkin, T S Godovikova, V F Zarytova, Miria Ricchetti, Olga I Lavrik | Comparison of interactions of 5'-deri... | |
| 1993 | S Kawa, A Kumar, J S Smith, S P Becerra, William A Beard, Samuel H Wilson, E B Thompson | Expression and purification of the HI... | |
| 1993 | T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley | A mutation in reverse transcriptase o... | |
| 1993 | Jörg-Peter Kleim, R Bender, U M Billhardt, C Meichsner, G Riess, M Rösner, I Winkler, A Paessens | Activity of a novel quinoxaline deriv... | |
| 1993 | G Maass, U Immendoerfer, B Koenig, U Leser, B Mueller, R Goody, E Pfaff | Viral resistance to the thiazolo-iso-... | |
| 1993 | Jan Balzarini, Anna Karlsson, A-M Vandamme, María-Jesús Pérez-Pérez, Haijiang Zhang, L Vrang, Bo Oberg, K Bäckbro, Torsten Unge, Ana San-Félix | Human immunodeficiency virus type 1 (... | |
| 1993 | Jan Balzarini, Sonsoles Velazquez, A San-Felix, Anna Karlsson, M J Perez-Perez, María-José Camarasa, Erik De Clercq | Human immunodeficiency virus type 1-s... | |
| 1993 | Jan Balzarini, Anna Karlsson, Erik De Clercq | Human immunodeficiency virus type 1 d... | |
| 1993 | M S Saag, E A Emini, O L Laskin, J Douglas, W I Lapidus, W A Schleif, R J Whitley, C Hildebrand, V W Byrnes, John C Kappes | A short-term clinical evaluation of L... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, L Vrang, J Walbers, Haijiang Zhang, Bo Oberg, A-M Vandamme, María-José Camarasa, Erik De Clercq | HIV-1-specific reverse transcriptase ... | |
| 1993 | John W Mellors, G J Im, Enzo Tramontano, S R Winkler, D J Medina, Ginger E Dutschman, Holly Z Bazmi, G Piras, C J Gonzalez, Yung-Chi Cheng | A single conservative amino acid subs... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, W G Tarpley, Erik De Clercq | Treatment of human immunodeficiency v... | |
| 1993 | Kristin A Eckert, Thomas A Kunkel | Fidelity of DNA synthesis catalyzed b... | Cloned or native,Full length or truncated,Specific Activity,3-5' exo,Nucleotide Substitution Rate,All properties |
| 1993 | M Tisdale, S D Kemp, N R Parry, Brendan A Larder | Rapid in vitro selection of human imm... | |
| 1993 | J L Martin, J E Wilson, R L Haynes, Phillip A Furman | Mechanism of resistance of human immu... | |
| 1993 | Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg | The same mutation that encodes low-le... | |
| 1993 | Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, Erik De Clercq | Knocking-out concentrations of HIV-1-... | |
| 1993 | J C Hsieh, S Zinnen, P Modrich | Kinetic mechanism of the DNA-dependen... | |
| 1993 | A Jacobo-Molina, Jianping Ding, R G Nanni, Arthur D Clark, Xiaoqing Lu, C Tantillo, R L Williams, G Kamer, Andrea L Ferris, Patrick K Clark | Crystal structure of human immunodefi... | |
| 1993 | W Y Gao, A Cara, R C Gallo, F Lori | Low levels of deoxynucleotides in per... | |
| 1993 | Johan Neyts, F Stals, C Bruggeman, Erik De Clercq | Activity of the anti-HIV agent 9-(2-p... | |
| 1993 | Erik De Clercq | HIV-1-specific RT inhibitors: highly ... | |
| 1993 | Zeger Debyser, K De Vreese, P P Knops-Gerrits, V Baekelandt, R Bhikhabhai, B Strandberg, Rudi Pauwels, J Anné, J Desmyter, Erik De Clercq | Kinetics of different human immunodef... | |
| 1993 | Erik De Clercq | Antiviral agents: characteristic acti... | |
| 1993 | Thomas A Steitz, S Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, J M Friedman, Lorena S Beese, P A Rice | Two DNA polymerases: HIV reverse tran... | |
| 1993 | D Chattopadhyay, B C Finzel, S H Munson, D B Evans, S K Sharma, N A Strakalaitus, D P Brunner, F M Eckenrode, Z Dauter, C Betzel, H M Einspahr | Crystallographic analyses of an activ... | |
| 1993 | Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors | Characterization of human immunodefic... | |
| 1993 | M S Chen, R T Suttmann, E Papp, P D Cannon, M J McRoberts, C Bach, William C Copeland, Teresa S-F Wang | Selective action of 4'-azidothymidine... | |
| 1993 | R Sousa, Y J Chung, J P Rose, B C Wang | Crystal structure of bacteriophage T7... | |
| 1993 | Myron F Goodman, S Creighton, Linda B Bloom, John Petruska | Biochemical basis of DNA replication ... | |
| 1993 | Paul L Boyer, M J Currens, James B McMahon, M R Boyd, Stephen H Hughes | Analysis of nonnucleoside drug-resist... | |
| 1992 | Paul L Boyer, Andrea L Ferris, Stephen H Hughes | Mutational analysis of the fingers do... | |
| 1992 | M Jiang, J Mak, Mark A. Wainberg, Michael A. Parniak, E Cohen, Lawrence Kleiman | Variable tRNA content in HIV-1IIIB. | |
| 1992 | J C Boyer, Katarzyna Bebenek, Thomas A Kunkel | Unequal human immunodeficiency virus ... | |
| 1992 | F Boulerice, R Geleziunas, S Bour, H L Li, M D'Addario, A Roulston, J Hiscott, Mark A. Wainberg | Differential susceptibilities of U-93... | |
| 1992 | Mark A. Wainberg, R G Margolese | Strategies in the treatment of AIDS a... | |
| 1992 | A Hosmalin, S Kumar, D Barnd, R Houghten, G E Smith, Stephen H Hughes, J A Berzofsky | Immunization with soluble protein-pul... | |
| 1992 | S Loya, R Tal, Stephen H Hughes, A Hizi | The effects of cysteine mutations on ... | |
| 1992 | William C Copeland, M S Chen, Teresa S-F Wang | Human DNA polymerases alpha and beta ... | |
| 1992 | I I Fedorov, E M Kazmina, N A Novicov, Galina V Gurskaya, A V Bochkarev, M V Jasko, L S Victorova, M K Kukhanova, Jan Balzarini, Erik De Clercq | 3'-C-branched 2'-deoxy-5-methyluridin... | |
| 1992 | N Yamamoto, Dominique Schols, Erik De Clercq, Zeger Debyser, Rudi Pauwels, Jan Balzarini, H Nakashima, Masanori Baba, M Hosoya, Robert Snoeck | Mechanism of anti-human immunodeficie... | |
| 1992 | G T Tan, J F Miller, A D Kinghorn, Stephen H Hughes, J M Pezzuto | HIV-1 and HIV-2 reverse transcriptase... | |
| 1992 | Zeger Debyser, K De Vreese, Rudi Pauwels, N Yamamoto, J Anné, Erik De Clercq, J Desmyter | Differential inhibitory effects of TI... | |
| 1992 | Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, Masanori Baba, J Desmyter, Erik De Clercq | Kinetics of inhibition of endogenous ... | |
| 1992 | K De Vreese, Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, J Desmyter, Erik De Clercq, J Anné | Resistance of human immunodeficiency ... | |
| 1992 | Erik De Clercq | HIV inhibitors targeted at the revers... | |
| 1992 | Erik De Clercq | New perspectives for the chemotherapy... | |
| 1992 | Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Y Engelborghs, Paul A J Janssen, Erik De Clercq | Allosteric inhibition of human immuno... | |
| 1992 | Zeger Debyser, Rudi Pauwels, Koen Andries, Erik De Clercq | Specific HIV-1 reverse transcriptase ... | |
| 1992 | J P Ji, Lawrence A Loeb | Fidelity of HIV-1 reverse transcripta... | |
| 1992 | M M Huang, Norman Arnheim, Myron F Goodman | Extension of base mispairs by Taq DNA... | |
| 1992 | Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg | Novel mutation in the human immunodef... | |
| 1992 | Z Hostomsky, Z Hostomska, T B Fu, J Taylor | Reverse transcriptase of human immuno... | |
| 1992 | P Kellam, Charles A B Boucher, Brendan A Larder | Fifth mutation in human immunodeficie... | |
| 1992 | S F Lacey, J E Reardon, E S Furfine, Thomas A Kunkel, Katarzyna Bebenek, Kristin A Eckert, S D Kemp, Brendan A Larder | Biochemical studies on the reverse tr... | |
| 1992 | Brendan A Larder | 3'-Azido-3'-deoxythymidine resistance... | |
| 1992 | Edward Arnold, A Jacobo-Molina, R G Nanni, R L Williams, Xiaoqing Lu, Jianping Ding, Art D Clark, A Zhang, Andrea L Ferris, Patrick K Clark | Structure of HIV-1 reverse transcript... | |
| 1992 | L A Kohlstaedt, Thomas A Steitz | Reverse transcriptase of human immuno... | |
| 1992 | Tsuyoshi Yamaguchi, Shunji Izuta, Motoshi Suzuki, Shonen Yoshida, Akio Matsukage, Mineo Saneyoshi | Inhibitory effects of 2'-deoxy-5-styr... | |
| 1992 | J J DeStefano, R G Buiser, L M Mallaber, P J Fay, Robert A Bambara | Parameters that influence processive ... | RT,Full length or truncated,Specific Activity,Processivity,Molecular Weight,RNase H,All properties |
| 1992 | A Basu, K K Ahluwalia, S Basu, Mukund J Modak | Identification of the primer binding ... | |
| 1992 | J A Coates, Nick Cammack, H J Jenkinson, I M Mutton, B A Pearson, R Storer, J M Cameron, C R Penn | The separated enantiomers of 2'-deoxy... | |
| 1992 | J A Coates, Nick Cammack, H J Jenkinson, A J Jowett, M I Jowett, B A Pearson, C R Penn, P L Rouse, K C Viner, J M Cameron | (-)-2'-deoxy-3'-thiacytidine is a pot... | |
| 1992 | D L Mayers, F E McCutchan, E E Sanders-Buell, L I Merritt, S Dilworth, A K Fowler, C A Marks, N M Ruiz, Douglas D Richman, C R Roberts | Characterization of HIV isolates aris... | |
| 1992 | John W Mellors, Ginger E Dutschman, G J Im, Enzo Tramontano, S R Winkler, Yung-Chi Cheng | In vitro selection and molecular char... | |
| 1992 | R L Mitina, S V Doronin, M I Dobrikov, D R Tabatadze, A S Levina, Olga I Lavrik | Human immunodeficiency virus type 1 r... | |
| 1992 | W M Kati, Kenneth A Johnson, L F Jerva, Karen S Anderson | Mechanism and fidelity of HIV reverse... | |
| 1992 | G T Tan, A Wickramasinghe, S Verma, R Singh, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan | Potential anti-AIDS naphthalenesulfon... | |
| 1992 | Hong Yu, Myron F Goodman | Comparison of HIV-1 and avian myelobl... | |
| 1992 | V V Sardana, E A Emini, L Gotlib, D J Graham, D W Lineberger, W J Long, A J Schlabach, J A Wolfgang, J H Condra | Functional analysis of HIV-1 reverse ... | |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velazquez, María-José Camarasa, Erik De Clercq | [2',5'-Bis-O-(tert-butyldimethylsilyl... | |
| 1992 | J E Reardon | Human immunodeficiency virus reverse ... | |
| 1992 | M Bakhanashvili, A Hizi | Fidelity of the reverse transcriptase... | RT,3-5' exo,All properties |
| 1992 | J A Peliska, Stephen J Benkovic | Mechanism of DNA strand transfer reac... | |
| 1992 | M B Vasudevachari, C Battista, H C Lane, M C Psallidopoulos, B Zhao, J Cook, J R Palmer, D L Romero, W G Tarpley, N P Salzman | Prevention of the spread of HIV-1 inf... | |
| 1992 | A Basu, S Basu, Mukund J Modak | Structure-activity analyses of HIV-1 ... | |
| 1992 | Q Gao, Z X Gu, Michael A. Parniak, X G Li, Mark A. Wainberg | In vitro selection of variants of hum... | |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Dominique Schols, CF Perno, A-M Vandamme, María-José Camarasa, Erik De Clercq | 2',5'-Bis-O-(tert-butyldimethylsilyl)... | |
| 1992 | Shunji Izuta, N Shimada, Masatoshi Kitagawa, Motoshi Suzuki, K Kojima, Shonen Yoshida | Inhibitory effects of triphosphate de... | |
| 1992 | L A Kohlstaedt, Jianhong Wang, J M Friedman, P A Rice, Thomas A Steitz | Crystal structure at 3.5 A resolution... | |
| 1992 | J Abbotts, Samuel H Wilson | Inhibitors of HIV-1 reverse transcrip... | |
| 1992 | Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, I C Bathurst, P J Barr, Erik De Clercq | Kinetics of inhibition of human immun... | |
| 1992 | Alberto Bergamini, CF Perno, Jan Balzarini, M Capozzi, Luciana Marinelli, G Milanese, C D Pesce, R Calió, G Rocchi | Selective inhibition of HIV replicati... | |
| 1992 | L Ding, Jan Balzarini, Dominique Schols, B Meunier, Erik De Clercq | Anti-human immunodeficiency virus eff... | |
| 1992 | V Gopalakrishnan, J A Peliska, Stephen J Benkovic | Human immunodeficiency virus type 1 r... | RT,Terminal Transferase,RNase H,All properties |
| 1992 | C S Crumpacker | Mechanism of action of foscarnet agai... | |
| 1991 | D Richman, C K Shih, I Lowy, J Rose, P Prodanovich, S Goff, J Griffin | Human immunodeficiency virus type 1 m... | |
| 1991 | Jan Balzarini, Antonin Holy, J Jindrich, H Dvorakova, Z Hao, Robert Snoeck, Piet Herdewijn, D G Johns, Erik De Clercq | 9-[(2RS)-3-fluoro-2-phosphonylmethoxy... | |
| 1991 | P Hafkemeyer, K Neftel, R Hobi, A Pfaltz, H Lutz, K Lüthi, Federico Focher, Silvio Spadari, Ulrich Hübscher | HP 0.35, a cephalosporin degradation ... | RT,RNase H,All properties |
| 1991 | R S Goody, B Müller, Tobias Restle | Factors contributing to the inhibitio... | |
| 1991 | Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Michael Kukla, Paul A J Janssen, Erik De Clercq | An antiviral target on reverse transc... | |
| 1991 | E S Furfine, J E Reardon | Reverse transcriptase.RNase H from th... | RT,All properties |
| 1991 | Brendan A Larder, K E Coates, S D Kemp | Zidovudine-resistant human immunodefi... | |
| 1991 | E B Kopp, J J Miglietta, A G Shrutkowski, C K Shih, P M Grob, M T Skoog | Steady state kinetics and inhibition ... | KM,kcat,All properties |
| 1991 | M H St Clair, J L Martin, G Tudor-Williams, M C Bach, C L Vavro, D M King, P Kellam, S D Kemp, Brendan A Larder | Resistance to ddI and sensitivity to ... | |
| 1991 | A DeVico, R C Montelaro, R C Gallo, M G Sarngadharan | Purification and partial characteriza... | RT,Full length or truncated,3-5' exo,Nucleotide Substitution Rate,RNase H,All properties |
| 1991 | J H Nunberg, W A Schleif, E J Boots, J A O'Brien, J C Quintero, J M Hoffman, E A Emini, M E Goldman | Viral resistance to human immunodefic... | |
| 1991 | Olga I Lavrik | Oligonucleotides and their derivative... | |
| 1991 | S P Becerra, A Kumar, M S Lewis, S G Widen, J Abbotts, E M Karawya, Stephen H Hughes, J Shiloach, Samuel H Wilson, M S Lewis | Protein-protein interactions of HIV-1... | |
| 1991 | Robert W Sobol, R J Suhadolnik, A Kumar, B J Lee, D L Hatfield, Samuel H Wilson | Localization of a polynucleotide bind... | |
| 1991 | J G Baillon, N T Nashed, A Kumar, Samuel H Wilson, Donald M Jerina | A leucine zipper-like motif may media... | |
| 1991 | J Abbotts, M Jaju, Samuel H Wilson | Thermodynamics of A:G mismatch poly(d... | |
| 1991 | A Hizi, R Tal, Stephen H Hughes | Mutational analysis of the DNA polyme... | |
| 1991 | A S De Groot, M Clerici, A Hosmalin, Stephen H Hughes, D Barnd, C W Hendrix, R Houghten, G M Shearer, J A Berzofsky | Human immunodeficiency virus reverse ... | |
| 1991 | Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, R T Walker, S Mori | Highly potent and selective inhibitio... | |
| 1991 | Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, H Nakashima, S Mori | Potent and selective inhibition of hu... | |
| 1991 | Erik De Clercq | Chemotherapy of the acquired immune d... | |
| 1991 | Mark Cushman, S Kanamathareddy, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen | Synthesis and anti-HIV activities of ... | |
| 1991 | Mark Cushman, P L Wang, S H Chang, C Wild, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen | Preparation and anti-HIV activities o... | |
| 1991 | G T Tan, A D Kinghorn, Stephen H Hughes, J M Pezzuto | Psychotrine and its O-methyl ether ar... | |
| 1991 | P R Johnson, T E Hamm, S Goldstein, S Kitov, V M Hirsch | The genetic fate of molecularly clone... | |
| 1991 | Mark A. Wainberg, R Rooke, M Tremblay, Xincang Li, Michael A. Parniak, Q Gao, X J Yao, C Tsoukas, J Montaner, M Fanning, J Ruedy | Clinical significance and characteriz... | |
| 1991 | F Boulerice, X G Li, A Lvovich, Mark A. Wainberg | Recovery of infectious human immunode... | |
| 1991 | A Jacobo-Molina, Edward Arnold | HIV reverse transcriptase structure-f... | |
| 1991 | K B Frank, G J Noll, E V Connell, I S Sim | Kinetic interaction of human immunode... | |
| 1991 | Stuart F J Le Grice, T Naas, B Wohlgensinger, O Schatz | Subunit-selective mutagenesis indicat... | |
| 1991 | J E Reardon, E S Furfine, N Cheng | Human immunodeficiency virus reverse ... | |
| 1991 | M Tisdale, T Schulze, Brendan A Larder, K Moelling | Mutations within the RNase H domain o... | |
| 1990 | A M Barber, A Hizi, J V Maizel, Stephen H Hughes | HIV-1 reverse transcriptase: structur... | |
| 1990 | M Ricchetti, H Buc | Reverse transcriptases and genomic va... | |
| 1990 | A Hizi, Stephen H Hughes, M Shaharabany | Mutational analysis of the ribonuclea... | |
| 1990 | Stuart F J Le Grice, F Grüninger-Leitch | Rapid purification of homodimer and h... | |
| 1990 | M Tremblay, K Numazaki, X G Li, M Gornitsky, J Hiscott, Mark A. Wainberg | Resistance to infection by HIV-1 of p... | |
| 1990 | W E Müller, E Matthes, P Reuter, R Wenger, K Friese, Y Kuchino, H C Schröder | Effect of nonviable preparations from... | |
| 1990 | Mark A. Wainberg, Bonnie Spira, G Bleau, R Thomas | Inactivation of human immunodeficienc... | |
| 1990 | M Tremblay, K Numazaki, H Goldman, Mark A. Wainberg | Infection of human thymic lymphocytes... | |
| 1990 | A I Glukhov, S A Gordeev, S V Vinogradov, V I Kiselev, V M Kramarov, O I Kiselev, E S Severin | Amplification of DNA sequences of Eps... | |
| 1990 | Padmini S Kedar, J Abbotts, T Kovács, K Lesiak, P Torrence, Samuel H Wilson | Mechanism of HIV reverse transcriptas... | |
| 1990 | S P Becerra, G M Clore, A M Gronenborn, A R Karlström, S J Stahl, Samuel H Wilson, P T Wingfield | Purification and characterization of ... | |
| 1990 | Andrea L Ferris, A Hizi, S D Showalter, S Pichuantes, L Babe, C S Craik, Stephen H Hughes | Immunologic and proteolytic analysis ... | |
| 1990 | V J Merluzzi, K D Hargrave, M Labadia, K Grozinger, M Skoog, J C Wu, C K Shih, K Eckner, S Hattox, J Adams | Inhibition of HIV-1 replication by a ... | |
| 1990 | K J Williams, Lawrence A Loeb, M Fry | Synthesis of DNA by human immunodefic... | |
| 1990 | J E Reardon, W H Miller | Human immunodeficiency virus reverse ... | KM,kcat,All properties |
| 1990 | Brendan A Larder, B Chesebro, Douglas D Richman | Susceptibilities of zidovudine-suscep... | |
| 1990 | Z Hao, D A Cooney, D Farquhar, CF Perno, K Zhang, R Masood, Y Wilson, N R Hartman, Jan Balzarini, D G Johns | Potent DNA chain termination activity... | |
| 1990 | Erik De Clercq | Selective virus inhibitors. | |
| 1990 | R Rooke, M Tremblay, Mark A. Wainberg | AZT (zidovudine) may act postintegrat... | |
| 1990 | Erik De Clercq | Targets and strategies for the antivi... | |
| 1990 | F Boulerice, Mark A. Wainberg | Inhibition by AZT of HIV-1 replicatio... | |
| 1989 | Fred W Perrino, Bradley D Preston, L L Sandell, Lawrence A Loeb | Extension of mismatched 3' termini of... | |
| 1989 | Erik De Clercq | Potential drugs for the treatment of ... | |
| 1989 | M Ito, Masanori Baba, A Sato, K Hirabayashi, F Tanabe, S Shigeta, Erik De Clercq | Tumor necrosis factor enhances replic... | |
| 1989 | Brendan A Larder, S D Kemp | Multiple mutations in HIV-1 reverse t... | |
| 1989 | A Basu, R S Tirumalai, Mukund J Modak | Substrate binding in human immunodefi... | |
| 1989 | H E Huber, J M McCoy, J S Seehra, Charles C Richardson | Human immunodeficiency virus 1 revers... | Processivity,3-5' exo,5-3' exo,KM,Kd,RNase H,All properties |
| 1989 | C Majumdar, C A Stein, J S Cohen, S Broder, Samuel H Wilson | Stepwise mechanism of HIV reverse tra... | |
| 1989 | Masanori Baba, Hiromichi Tanaka, Erik De Clercq, Rudi Pauwels, Jan Balzarini, Dominique Schols, H Nakashima, CF Perno, R T Walker, T Miyasaka | Highly specific inhibition of human i... | |
| 1989 | M Tremblay, M Gornitsky, Mark A. Wainberg | Active replication of human immunodef... | |
| 1989 | B Müller, Tobias Restle, S Weiss, M Gautel, G Sczakiel, R S Goody | Co-expression of the subunits of the ... | |
| 1989 | Dominique Schols, Masanori Baba, Rudi Pauwels, Erik De Clercq | Flow cytometric method to demonstrate... | |
| 1989 | K Numazaki, X Q Bai, H Goldman, I Wong, Bonnie Spira, Mark A. Wainberg | Infection of cultured human thymic ep... | |
| 1989 | M Tremblay, Mark A. Wainberg | Susceptibility of EBV-carrying B cell... | |
| 1989 | A Hizi, A Barber, Stephen H Hughes | Effects of small insertions on the RN... | |
| 1989 | Masanori Baba, Dominique Schols, H Nakashima, Rudi Pauwels, G Parmentier, D K Meijer, Erik De Clercq | Selective activity of several cholic ... | |
| 1988 | Bradley D Preston, B J Poiesz, Lawrence A Loeb | Fidelity of HIV-1 reverse transcriptase. | |
| 1988 | E M Wondrak, J Löwer, R Kurth | Inhibition of HIV-1 RNA-dependent DNA... | |
| 1988 | A Hizi, C McGill, Stephen H Hughes | Expression of soluble, enzymatically ... | |
| 1988 | M Tremblay, L Fitz-Gibbon, Mark A. Wainberg | Heterogeneity of HIV-1 replication an... | |
| 1988 | Sujit Roy, L Fitz-Gibbon, L Poulin, Mark A. Wainberg | Infection of human monocytes/macropha... | |
| 1988 | J D Roberts, Katarzyna Bebenek, Thomas A Kunkel | The accuracy of reverse transcriptase... | |
| 1988 | Masanori Baba, Dominique Schols, Rudi Pauwels, Jan Balzarini, Erik De Clercq | Fuchsin acid selectively inhibits hum... | |
| 1988 | Masanori Baba, Rudi Pauwels, Jan Balzarini, J Arnout, J Desmyter, Erik De Clercq | Mechanism of inhibitory effect of dex... | |
| 1988 | Erik De Clercq | Perspectives for the chemotherapy of ... | |
| 1987 | Brendan A Larder, D J Purifoy, K L Powell, G Darby | Site-specific mutagenesis of AIDS vir... | |
| 1987 | M Ito, H Nakashima, Masanori Baba, Rudi Pauwels, Erik De Clercq, S Shigeta, N Yamamoto | Inhibitory effect of glycyrrhizin on ... | |
| 1986 | M S Johnson, M A McClure, D F Feng, J Gray, R F Doolittle | Computer analysis of retroviral pol g... | |
| 1986 | F di Marzo Veronese, T D Copeland, A L DeVico, R Rahman, S Oroszlan, R C Gallo, M G Sarngadharan | Characterization of highly immunogeni... | |
| 1986 | H A Blough, Rudi Pauwels, Erik De Clercq, J Cogniaux, S Sprecher-Goldberger, L Thiry | Glycosylation inhibitors block the ex... | |
| 1986 | M M Lightfoote, J E Coligan, T M Folks, A S Fauci, M A Martin, S Venkatesan | Structural characterization of revers... | |
| 1985 | A D Hoffman, B Banapour, J A Levy | Characterization of the AIDS-associat... |
DNA sequence:
Protein information: Uniprot Q8Q292 search for HIV RT at UniProt
Sequence information: NCBI nucleotides European nucleotide archive