Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism.

Sawaya MR, Prasad R, Wilson SH, Kraut J, Pelletier H
Biochemistry (1997), Volume 36, Page 11205
PubMed entry Publisher's site

Polymerases:

Human Pol beta

Topics:

Historical Protein Properties (MW, pI, ...), Structure and Structure/Function, Nucleotide Incorporation, Exonuclease Activity, Source / Purification

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
Human Pol beta Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Nick Extension Yes, via strand displacement
Human Pol beta Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Molecular Weight 39kD
Human Pol beta Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. 3-5' Exonuclease (proofreading) No
Human Pol beta Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. 5-3' Exonuclease No
Human Pol beta Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Full length or truncated Full length
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Structures:

1BPX 1BPY 1BPZ

Version:20240415

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