Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism.

Polymerases:

Topics:

Historical Protein Properties (MW, pI, ...), Structure and Structure/Function, Nucleotide Incorporation, Exonuclease Activity, Source / Purification

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
Human Pol beta Sawaya MR1997 Nick Extension Yes, via strand displacement
Human Pol beta Sawaya MR1997 Molecular Weight 39kD
Human Pol beta Sawaya MR1997 3-5' Exonuclease (proofreading) No
Human Pol beta Sawaya MR1997 5-3' Exonuclease No
Human Pol beta Sawaya MR1997 Full length or truncated Full length

Entry validated by:

Structures:

1BPX 1BPY 1BPZ
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