The M184V mutation in HIV-1 reverse transcriptase reduces the restoration of wild-type replication by attenuated viruses.

Wei X, Liang C, Götte M, Wainberg MA
AIDS (London, England) (2002), Volume 16, Page 2391
PubMed entry

Abstract:

To study the ability of HIV constructs containing the M184V ...
To study the ability of HIV constructs containing the M184V substitution in reverse transcriptase (RT), which causes resistance to lamivudine, to evolve mutations that compensate for deletions within the HIV genome.

Polymerases:

HIV RT

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