show help

Masutani C

Author page

This page provides a summary of the entries in Polbase associated with this author.

The publication history graph presents the number of publications in Polbase by this author over time.

The polymerase chart indicates which polymerases this author has published on.

Polbase automatically discovers many polymerase papers as they are published. Some relevant papers are not included because the algorithm is designed to reduce background. Please contribute to polbase by adding your missing DNA polymerase papers.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Missing references?

Publications:

Title Authors Year Journal
A cyclobutane thymine-N4-methylcytosine dimer is resistant to hydrolysis but strongly blocks DNA synthesis. Masutani C 2013 Nucleic acids research
Structure and mechanism of human DNA polymerase η Masutani C 2011 Nature
Photosensitized [2 + 2] cycloaddition of N-acetylated cytosine affords stereoselective formation of cyclobutane pyrimidine dimer. Masutani C 2011 Nucleic acids research
Structure and mechanism of human DNA polymerase eta. Masutani C 2010 Nature
Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions. Masutani C 2010 PLoS genetics
The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells. Masutani C 2010 Molecular cell
Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana. Masutani C 2010 Journal of nucleic acids
Polymerization by DNA polymerase eta is blocked by cis-diamminedichloroplatinum(II) 1,3-d(GpTpG) cross-link: implications for cytotoxic effects in nucleotide excision repair-negative tumor cells. Masutani C 2010 Carcinogenesis
Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells. Masutani C 2009 DNA repair
A novel interaction between human DNA polymerase eta and MutLalpha. Masutani C 2009 Biochem Biophys Res Commun
Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus. Masutani C 2009 The Journal of biological chemistry
Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases. Masutani C 2009 Bioorganic & medicinal chemistry
Specificity of mutations induced by incorporation of oxidized dNTPs into DNA by human DNA polymerase eta. Masutani C 2008 DNA repair
Translesion synthesis across the (6-4) photoproduct and its Dewar valence isomer by the Y-family and engineered DNA polymerases. Masutani C 2008 Nucleic acids symposium series (2004)
Use of RNAi in C. elegans. Masutani C 2008 Methods in molecular biology (Clifton, N.J.)
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes. Masutani C 2007 The Journal of biological chemistry
Efficient and erroneous incorporation of oxidized DNA precursors by human DNA polymerase eta. Masutani C 2007 Biochemistry
2-Hydroxy-2'-deoxyadenosine 5'-triphosphate enhances A.T --> C.G mutations caused by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate by suppressing its degradation upon replication in a HeLa extract. Masutani C 2007 Biochemistry
A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase eta activity. Masutani C 2007 The Journal of biological chemistry
UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota. Masutani C 2006 Molecular and cellular biology
Deficiency of the Caenorhabditis elegans DNA polymerase eta homologue increases sensitivity to UV radiation during germ-line development. Masutani C 2006 Cell Struct Funct
A human DNA polymerase eta complex containing Rad18, Rad6 and Rev1; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest. Masutani C 2006 Genes Cells
Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification. Masutani C 2005 Proceedings of the National Academy of Sciences of the United States of America
Dual roles for DNA polymerase eta in homologous DNA recombination and translesion DNA synthesis. Masutani C 2005 Molecular cell
Error-prone translesion synthesis by human DNA polymerase eta on DNA-containing deoxyadenosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Masutani C 2005 The Journal of biological chemistry
Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. Masutani C 2004 Nature
Translesion synthesis past estrogen-derived DNA adducts by human DNA polymerases eta and kappa. Masutani C 2004 Biochemistry
Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity. Masutani C 2004 Molecular and cellular biology
Chemical synthesis and translesion replication of a cis-syn cyclobutane thymine-uracil dimer. Masutani C 2004 Nucleic acids research
High-efficiency bypass of DNA damage by human DNA polymerase Q. Masutani C 2004 The EMBO journal
DNA binding properties of human DNA polymerase eta: implications for fidelity and polymerase switching of translesion synthesis. Masutani C 2004 Genes Cells
Erroneous incorporation of oxidized DNA precursors by Y-family DNA polymerases. Masutani C 2003 EMBO reports
8-Hydroxyguanine in a mutational hotspot of the c-Ha-ras gene causes misreplication, 'action-at-a-distance' mutagenesis and inhibition of replication. Masutani C 2003 Nucleic acids research
129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation. Masutani C 2003 J Exp Med
Identification and characterization of an intermediate in the alkali degradation of (6-4) photoproduct-containing DNA. Masutani C 2003 The Journal of biological chemistry
Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts. Masutani C 2002 The Journal of biological chemistry
[DNA polymerase eta: from a DNA repair-deficient genetic disease to the discovery of a novel DNA polymerase]. Masutani C 2002 Seikagaku
Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients. Masutani C 2002 Proceedings of the National Academy of Sciences of the United States of America
Translesion synthesis by human DNA polymerase eta across thymine glycol lesions. Masutani C 2002 Biochemistry
Proofreading of DNA polymerase eta-dependent replication errors. Masutani C 2001 The Journal of biological chemistry
Oxygen free radical damage to DNA. Translesion synthesis by human DNA polymerase eta and resistance to exonuclease action at cyclopurine deoxynucleoside residues. Masutani C 2001 The Journal of biological chemistry
Mutagenic and nonmutagenic bypass of DNA lesions by Drosophila DNA polymerases dpoleta and dpoliota. Masutani C 2001 The Journal of biological chemistry
Error rate and specificity of human and murine DNA polymerase eta. Masutani C 2001 Journal of molecular biology
Low fidelity DNA synthesis by human DNA polymerase-eta. Masutani C 2000 Nature
Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa. Masutani C 2000 Genes Dev
Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase eta. Masutani C 2000 Nucleic acids research
Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase eta. Masutani C 2000 Biochemistry
Genomic structure, chromosomal localization and identification of mutations in the xeroderma pigmentosum variant (XPV) gene. Masutani C 2000 Oncogene
Xeroderma pigmentosum variant: from a human genetic disorder to a novel DNA polymerase. Masutani C 2000 Cold Spring Harbor symposia on quantitative biology
Mechanisms of accurate translesion synthesis by human DNA polymerase eta. Masutani C 2000 The EMBO journal
Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. Masutani C 1999 The EMBO journal
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta. Masutani C 1999 Nature
8-Hydroxyadenine (7,8-dihydro-8-oxoadenine) induces misincorporation in in vitro DNA synthesis and mutations in NIH 3T3 cells. Masutani C 1995 Nucleic acids research
Stimulation of DNA synthesis by mouse DNA helicase B in a DNA replication system containing eukaryotic replication origins. Masutani C 1995 Biochemistry
Comparison of incorporation and extension of nucleotides in vitro opposite 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in hot spots of the c-Ha-ras gene. Masutani C 1995 Japanese journal of cancer research : Gann
Cyclobutane thymine dimers in a ras proto-oncogene hot spot activate the gene by point mutation. Masutani C 1993 Nucleic acids research
Mouse DNA primase plays the principal role in determination of permissiveness for polyomavirus DNA replication. Masutani C 1991 Journal of virology
DNA primase stimulatory factor from mouse FM3A cells has an RNase H activity. Purification of the factor and analysis of the stimulation. Masutani C 1990 The Journal of biological chemistry
DNA primase-DNA polymerase alpha assembly from mouse FM3A cells. Purification of constituting enzymes, reconstitution, and analysis of RNA priming as coupled to DNA synthesis. Masutani C 1989 The Journal of biological chemistry

Version:20241218

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.