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Polymerase: Human Pol kappa

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Polymerase	Reference	Property	Result	Context
Human Pol kappa	Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene.	3-5' Exonuclease (proofreading)	No
Human Pol kappa	Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene.	Cloned or native	Insect cells
Human Pol kappa	Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene.	Template lesions	Bypasses	Reaction: Nucleotide incorporation
Human Pol kappa	Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene.	Tagged	Yes
Human Pol kappa	Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene.	Tag Name	GST
Human Pol kappa	Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene.	Full length or truncated	Full length
Human Pol kappa	Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene.	Processivity	1bp
Human Pol kappa	Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.	3-5' Exonuclease (proofreading)	No
Human Pol kappa	Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.	Cloned or native	Native organism
Human Pol kappa	Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.	Tagged	Yes
Human Pol kappa	Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.	Tag Name	GST, His
Human Pol kappa	Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.	Nucleotide Substitution Rate	0.0058 errors/bp
Human Pol kappa	Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.	Full length or truncated	Full length
Human Pol kappa	Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.	Processivity	25bp
Human Pol kappa	Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.	Gap Filling	Yes
Human Pol kappa	Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates.	3-5' Exonuclease (proofreading)	No
Human Pol kappa	Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates.	Nucleotide Substitution Rate	0.0066 errors/bp
Human Pol kappa	Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates.	Full length or truncated	Full length
Human Pol kappa	The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases.	Frameshift Error Rate	0.0018 errors/bp	Technique: M13mp2 forward mutation assay
Human Pol kappa	The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases.	Nucleotide Substitution Rate	0.0058 errors/bp	Technique: M13mp2 forward mutation assay
Human Pol kappa	Replication, Repair and Translesion Polymerase Bypass of N6-Oxopropenyl-2'-deoxyadenosine.	Template lesions	Bypasses	Reaction: Nucleotide incorporation; Substrate: dTTP; DNA lesion: OPdA