T4 D219A

From bacteriophage T4
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Welcome to the Polymerase Page

This page presents all the information in Polbase for T4 D219A.

Mutants:

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Structures/Sequence:

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Mutant of: T4 (D219A)

T4 D219A is a family B enzyme from bacteriophage T4.

Selected Properties for T4 D219A:

 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (2) no data no data 4.0e-05-7.6e+02 errors/bp, Mutation frequency (relative to WT) (4) 1.2e-05 errors/bp (1)
Year Authors Title Results by property
2008 Linda J Reha-Krantz Recent patents of gene sequences rela...
2007 Dina Tleugabulova, Linda J Reha-Krantz Probing DNA polymerase-DNA interactio... 3-5' exo,All properties
2006 Matthew Hogg, Wendy Cooper, Linda J Reha-Krantz, Susan S Wallace Kinetics of error generation in homol... Kd,kcat,All properties
2004 Charles E Jones, Timothy C Mueser, Nancy G Nossal Bacteriophage T4 32 protein is requir...
2003 Emmanuelle Delagoutte, Peter H von Hippel Function and assembly of the bacterio... Kd,All properties
2001 Emmanuelle Delagoutte, Peter H von Hippel Molecular mechanisms of the functiona... Vmax,All properties
2001 M Bhagwat, Nancy G Nossal Bacteriophage T4 RNase H removes both... RNase H,All properties
2000 Paul D Chastain, Alexander M Makhov, Nancy G Nossal, Jack D Griffith Analysis of the Okazaki fragment dist...
1999 E Elisseeva, Subhrangsu S Mandal, Linda J Reha-Krantz Mutational and pH studies of the 3' -...
1998 D J Sexton, B F Kaboord, Anthony J Berdis, T E Carver, Stephen J Benkovic Dissecting the order of bacteriophage...
1998 Linda J Reha-Krantz Regulation of DNA polymerase exonucle...
1998 L C Kroutil, M W Frey, B F Kaboord, Thomas A Kunkel, Stephen J Benkovic Effect of accessory proteins on T4 DN... 3-5' exo,5-3' exo,Nucleotide Substitution Rate,Overall Error Rate,All properties
1998 P Soumillion, D J Sexton, Stephen J Benkovic Clamp subunit dissociation dictates b...
1996 A K Abdus Sattar, T C Lin, C Jones, William H Konigsberg Functional consequences and exonuclea... KM,kcat,All properties
1996 D J Sexton, T E Carver, Anthony J Berdis, Stephen J Benkovic Protein-protein and protein-DNA inter...
1993 M W Frey, Nancy G Nossal, T L Capson, Stephen J Benkovic Construction and characterization of ... Nucleotide Substitution Rate,Kd,kcat,All properties
1993 Linda J Reha-Krantz, R L Nonay Genetic and biochemical studies of ba... Nucleotide Substitution Rate,All properties

Version:20240425

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