Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Sweeney ZK, Dunn JP, Li Y, Heilek GM, Dunten PW, Elworthy TR, Han X, Harris SF, Hirschfeld DR, Hogg JH, Huber W, Kaiser AC, Kertesz DJ, Kim W, Mirzadegan T, Roepel MG, Saito YD, Silva TM, Swallow S, Tracy JL, Villasenor A, Vora H, Zhou AS, Klumpp K
Bioorganic & medicinal chemistry letters (2008), Volume 18, Page 4352
Abstract:
Polymerases:
Topics:
Structure and Structure/Function, Reverse Transcriptase
Status:
| new | topics/pols set | partial results | complete | validated |
Results:
| Polymerase | Reference | Property | Result | Context |
|---|---|---|---|---|
| HIV RT | Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase. | Reverse Transcriptase Activity | Yes |