Bioorganic & medicinal chemistry letters

(Bioorg Med Chem Lett) ISSNs: , 1464-3405

References in Bioorganic & medicinal chemistry letters:

Title Authors Year
7-Alkyl-N(2)-substituted-3-deazaguanines. Synthesis, DNA polymerase III inhibition and antibacterial activity. Xu WC, Wright GE, Brown NC, Long ZY, Zhi CX, Dvoskin S, Gambino JJ, Barnes MH, Butler MM 2011
N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Mitchell ML, Son JC, Guo H, Im YA, Cho EJ, Wang J, Hayes J, Wang M, Paul A, Lansdon EB, Chen JM, Graupe D, Rhodes G, He GX, Geleziunas R, Xu L, Kim CU 2010
Novel non-nucleobase inhibitors of Staphylococcus aureus DNA polymerase IIIC. Rose Y, Ciblat S, Reddy R, Belley AC, Dietrich E, Lehoux D, McKay GA, Poirier H, Far AR, Delorme D 2006
Photoregulation of DNA polymerase I (Klenow) with caged fluorescent oligodeoxynucleotides. Tang X, Richards JL, Peritz AE, Dmochowski IJ 2005
Evolution of anti-HIV drug candidates. Part 2: Diaryltriazine (DATA) analogues. Ludovici DW, Kavash RW, Kukla MJ, Ho CY, Ye H, De Corte BL, Andries K, De Béthune MP, Azijn H, Pauwels R, Moereels HE, Heeres J, Koymans LM, De Jonge MR, Van Aken KJ, Daeyaert FF, Lewi PJ, Das K, Arnold E, Janssen PA 2001
Evolution of anti-HIV drug candidates. Part 1: From alpha-anilinophenylacetamide (alpha-APA) to imidoyl thiourea (ITU). Ludovici DW, Kukla MJ, Grous PG, Krishnan S, Andries K, De Béthune MP, Azijn H, Pauwels R, De Clercq E, Arnold E, Janssen PA 2001
Enzymatic synthesis of labeled DNA by PCR using new fluorescent thymidine nucleotide analogue and superthermophilic KOD dash DNA polymerase. Obayashi T, Masud MM, Ozaki AN, Ozaki H, Kuwahara M, Sawai H 2002
Inhibition of multi-drug resistant HIV-1 reverse transcriptase by nucleoside β-triphosphates. Dash C, Ahmadibeni Y, Hanley MJ, Pandhare J, Gotte M, Le Grice SF, Parang K 2011
Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs). Zhao Z, Wolkenberg SE, Sanderson PE, Lu M, Munshi V, Moyer G, Feng M, Carella AV, Ecto LT, Gabryelski LJ, Lai MT, Prasad SG, Yan Y, McGaughey GB, Miller MD, Lindsley CW, Hartman GD, Vacca JP, Williams TM 2008
Nucleosides and nucleotides. 183. Synthesis of 4'alpha-branched thymidines as a new type of antiviral agent. Sugimoto I, Shuto S, Mori S, Shigeta S, Matsuda A 1999
Effects of 8-chlorodeoxyadenosine on DNA synthesis by the Klenow fragment of DNA polymerase I. Chen LS, Bahr MH, Sheppard TL 2003
Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase--structure-activity relationships and crystallographic analysis. Kirschberg TA, Balakrishnan M, Huang W, Hluhanich R, Kutty N, Liclican AC, McColl DJ, Squires NH, Lansdon EB 2008
Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol. Pungitore CR, León LG, García C, Martín VS, Tonn CE, Padrón JM 2007
7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase. Larsen SD, Zhang Z, DiPaolo BA, Manninen PR, Rohrer DC, Hageman MJ, Hopkins TA, Knechtel ML, Oien NL, Rush BD, Schwende FJ, Stefanski KJ, Wieber JL, Wilkinson KF, Zamora KM, Wathen MW, Brideau RJ 2007
Synthetic analogues of the manzamenones and plakoridines which inhibit DNA polymerase. Doncaster JR, Etchells LL, Kershaw NM, Nakamura R, Ryan H, Takeuchi R, Sakaguchi K, Sardarian A, Whitehead RC 2006
Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants. Su DS, Lim JJ, Tinney E, Wan BL, Young MB, Anderson KD, Rudd D, Munshi V, Bahnck C, Felock PJ, Lu M, Lai MT, Touch S, Moyer G, Distefano DJ, Flynn JA, Liang Y, Sanchez R, Prasad S, Yan Y, Perlow-Poehnelt RA, Torrent M, Miller MD, Vacca JP, Williams TM, Anthony NJ 2009
Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses. Kertesz DJ, Brotherton-Pleiss C, Yang M, Wang Z, Lin X, Qiu Z, Hirschfeld DR, Gleason SK, Mirzadegan T, Dunten PW, Harris SF, Villaseñor AG, Hang JQ, Heilek GM, Klumpp K 2010
Incorporation of 4-thiothymidine into DNA by the Klenow fragment and HIV-1 reverse transcriptase. Rao TV, Haber MT, Sayer JM, Jerina DM 2000
Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase. Sweeney ZK, Dunn JP, Li Y, Heilek GM, Dunten PW, Elworthy TR, Han X, Harris SF, Hirschfeld DR, Hogg JH, Huber W, Kaiser AC, Kertesz DJ, Kim W, Mirzadegan T, Roepel MG, Saito YD, Silva TM, Swallow S, Tracy JL, Villasenor A, Vora H, Zhou AS, Klumpp K 2008
Evolution of anti-HIV drug candidates. Part 3: Diarylpyrimidine (DAPY) analogues. Ludovici DW, De Corte BL, Kukla MJ, Ye H, Ho CY, Lichtenstein MA, Kavash RW, Andries K, De Béthune MP, Azijn H, Pauwels R, Lewi PJ, Heeres J, Koymans LM, De Jonge MR, Van Aken KJ, Daeyaert FF, Das K, Arnold E, Janssen PA 2001
The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations. Tucker TJ, Saggar S, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey GB, Liu M, Miller MD, Moyer G, Munshi V, Perlow-Poehnelt RA, Prasad S, Sanchez R, Torrent M, Vacca JP, Wan BL, Yan Y 2008
Naphthalene carboxamides as inhibitors of human cytomegalovirus DNA polymerase. Vaillancourt VA, Cudahy MM, Staley SA, Brideau RJ, Conrad SJ, Knechtel ML, Oien NL, Wieber JL, Yagi Y, Wathen MW 2000
Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III. Guiles JW, Sun X, Critchley IA, Ochsner U, Tregay M, Stone K, Bertino J, Green LS, Sabin R, Dean F, Dallmann HG, McHenry CS, Janjic N 2009
N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Mitchell ML, Son JC, Lee IY, Lee CK, Kim HS, Guo H, Wang J, Hayes J, Wang M, Paul A, Lansdon EB, Chen JM, Eisenberg G, Geleziunas R, Xu L, Kim CU 2010
Small molecule inhibitors of HIV RT Ribonuclease H. Di Grandi M, Olson M, Prashad AS, Bebernitz G, Luckay A, Mullen S, Hu Y, Krishnamurthy G, Pitts K, O'Connell J 2010
Construction of saccharide-modified DNAs by DNA polymerase. Matsui M, Nishiyama Y, Ueji S, Ebara Y 2007
Design and synthesis of novel antibacterial agents with inhibitory activity against DNA polymerase III. Ali A, Aster SD, Graham DW, Patel GF, Taylor GE, Tolman RL, Painter RE, Silver LL, Young K, Ellsworth K, Geissler W, Harris GS 2001
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains. Barreca ML, Rao A, De Luca L, Iraci N, Monforte AM, Maga G, De Clercq E, Pannecouque C, Balzarini J, Chimirri A 2007
6-Benzoyl-3-hydroxypyrimidine-2,4-diones as dual inhibitors of HIV reverse transcriptase and integrase. Tang J, Maddali K, Dreis CD, Sham YY, Vince R, Pommier Y, Wang Z 2011
Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutants. Butini S, Gemma S, Brindisi M, Borrelli G, Fiorini I, Samuele A, Karytinos A, Facchini M, Lossani A, Zanoli S, Campiani G, Novellino E, Focher F, Maga G 2011
Synthesis of pyrimidine and quinolone conjugates as a scaffold for dual inhibitors of HIV reverse transcriptase and integrase. Wang Z, Vince R 2008
Exploration of piperidine-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Phenyl derivatives with broad potency against resistant mutant viruses. Tang G, Kertesz DJ, Yang M, Lin X, Wang Z, Li W, Qiu Z, Chen J, Mei J, Chen L, Mirzadegan T, Harris SF, Villaseñor AG, Fretland J, Fitch WL, Hang JQ, Heilek GM, Klumpp K 2010
5-Alkyl-2-[(aryl and alkyloxylcarbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones as an unique HIV reverse transcriptase inhibitors of S-DABO series. He Y, Chen F, Sun G, Wang Y, De Clercq E, Balzarini J, Pannecouque C 2004
Inhibition of tubulin polymerization by select alkenyldiarylmethanes. Cullen MD, Sarkar T, Hamel E, Hartman TL, Watson KM, Buckheit RW, Pannecouque C, De Clercq E, Cushman M 2008
Identification of a novel family of nucleosides that specifically inhibit HIV-1 reverse transcriptase. Chamorro C, Lobatón E, Bonache MC, De Clercq E, Balzarini J, Velázquez S, San-Félix A, Camarasa MJ 2001
Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs. Zhan P, Li X, Li Z, Chen X, Tian Y, Chen W, Liu X, Pannecouque C, De Clercq E 2012
4'C-ethynyl-thymidine acts as a chain terminator during DNA-synthesis catalyzed by HIV-1 reverse transcriptase. Summerer D, Marx A 2005
1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Zhan P, Liu X, Cao Y, Wang Y, Pannecouque C, De Clercq E 2008
Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors. Cullen MD, Cheung YF, Houslay MD, Hartman TL, Watson KM, Buckheit RW, Pannecouque C, De Clercq E, Cushman M 2008
Extension into the entrance channel of HIV-1 reverse transcriptase-Crystallography and enhanced solubility. Bollini M, Frey KM, Cisneros JA, Spasov KA, Das K, Bauman JD, Arnold E, Anderson KS, Jorgensen WL 2013
Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Chen X, Liu X, Meng Q, Wang D, Liu H, De Clercq E, Pannecouque C, Balzarini J, Liu X 2013
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