Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations.

Lee YS, Kennedy WD, Yin YW
Cell (2009), Volume 139, Page 312
PubMed entry Publisher's site

Abstract:

Human mitochondrial DNA polymerase (Pol gamma) is the sole replicase ...

Polymerases:

Topics:

Structure and Structure/Function, Source / Purification

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
Human Pol gamma Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. Polymerase Catalytic Residue Amino Acids D890,D1135
Human Pol gamma Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. Cloned or native Cloned in E. coli
Human Pol gamma Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. Tagged Yes
Human Pol gamma Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. Tag Name His
Human Pol gamma Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. Full length or truncated Truncated

Entry validated by:

Structures:

3IKL