Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation.
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Sugawara F
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2013
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Molecular medicine reports
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Characterization of marine X-family DNA polymerases and comparative analysis of base excision repair proteins.
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Sugawara F
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2011
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Biochemical and biophysical research communications
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A sulfoglycolipid beta-sulfoquinovosyldiacylglycerol (betaSQDG) binds to Met1-Arg95 region of murine DNA polymerase lambda (Mmpol lambda) and inhibits its nuclear transit.
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Sugawara F
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2010
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Protein Eng Des Sel
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β-Sitosteryl (6'-O-linoleoyl)-glucoside of soybean (Glycine max L.) crude extract inhibits Y-family DNA polymerases.
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Sugawara F
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2010
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Journal of oleo science
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Purified canola lutein selectively inhibits specific isoforms of mammalian DNA polymerases and reduces inflammatory response.
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Sugawara F
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2010
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Lipids
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The relationship between the molecular structure of natural acetogenins and their inhibitory activities which affect DNA polymerase, DNA topoisomerase and human cancer cell growth.
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Sugawara F
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2010
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Experimental and therapeutic medicine
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Inhibitory effects of diacylglyceride phospholipids on DNA polymerase and topoisomerase activities, and human cancer cell growth.
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Sugawara F
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2010
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Medicinal chemistry (Shāriqah (United Arab Emirates))
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Inhibitory effects of docosyl p-coumarate on DNA topoisomerase activity and human cancer cell growth.
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Sugawara F
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2010
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International journal of oncology
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Inhibitory effect of somatostatin Peptide analogues on DNA polymerase activity and human cancer cell proliferation.
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Sugawara F
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2010
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Anticancer Res
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The inhibitory action of kohamaic acid A derivatives on mammalian DNA polymerase beta.
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Sugawara F
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2009
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Molecules
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3-O-methylfunicone, a selective inhibitor of mammalian Y-family DNA polymerases from an Australian sea salt fungal strain.
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Sugawara F
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2009
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Marine drugs
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Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases.
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Sugawara F
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2009
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Bioorganic & medicinal chemistry
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Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth.
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Sugawara F
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2009
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Cancer Lett
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Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase alpha inhibitors.
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Sugawara F
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2009
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Bioorg Med Chem
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Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells.
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Sugawara F
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2008
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Molecules
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1-deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae.
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Sugawara F
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2008
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Bioorganic & medicinal chemistry
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The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase alpha.
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Sugawara F
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2008
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Int J Mol Med
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Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp.
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Sugawara F
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2008
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Bioorganic & medicinal chemistry
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Hymenoic acid, a novel specific inhibitor of human DNA polymerase lambda from a fungus of Hymenochaetaceae sp.
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Sugawara F
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2008
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Bioorg Med Chem
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Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp.
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Sugawara F
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2007
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Bioorg Med Chem
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Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.
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Sugawara F
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2007
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Biochem Biophys Res Commun
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Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases.
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Sugawara F
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2007
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Organic & biomolecular chemistry
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Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda.
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Sugawara F
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2006
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Genes Cells
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Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta.
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Sugawara F
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2006
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Biochem Biophys Res Commun
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Inhibitory effect of sulfoquinovosyl diacylglycerol on prokaryotic DNA polymerase I activity and cell growth of Escherichia coli.
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Sugawara F
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2006
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J Oleo Sci
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Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster.
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Sugawara F
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2006
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The FEBS journal
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5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase.
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Sugawara F
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2006
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Arch Biochem Biophys
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Sulfo-quinovosyl-acyl-glycerol (SQAG), a eukaryotic DNA polymerase inhibitor and anti-cancer agent.
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Sugawara F
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2005
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Curr Med Chem Anticancer Agents
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Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin.
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Sugawara F
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2005
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Biochimica et biophysica acta
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Mammalian mitotic centromere-associated kinesin (MCAK): a new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents.
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Sugawara F
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2005
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The FEBS journal
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Effective form of sulfoquinovosyldiacyglycerol (SQDG) vesicles for DNA polymerase inhibition.
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Sugawara F
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2005
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Colloids Surf B Biointerfaces
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Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors.
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Sugawara F
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2005
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Life Sci
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Affinity capture of a mammalian DNA polymerase beta by inhibitors immobilized to resins used in solid-phase organic synthesis.
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Sugawara F
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2005
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Bioconjug Chem
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Monoacetylcurcumin: a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography.
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Sugawara F
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2005
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Biochem Biophys Res Commun
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Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta.
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Sugawara F
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2005
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FEBS J
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Structural analysis of catechin derivatives as mammalian DNA polymerase inhibitors.
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Sugawara F
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2005
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Biochem Biophys Res Commun
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Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.
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Sugawara F
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2005
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Int J Mol Med
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Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors.
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Sugawara F
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2004
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Bioorganic & medicinal chemistry
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Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.
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Sugawara F
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2004
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Bioorg Med Chem
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Molecular design of cholesterols as inhibitors of DNA polymerase alpha.
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Sugawara F
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2004
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J Med Chem
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Taxol derivatives are selective inhibitors of DNA polymerase alpha.
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Sugawara F
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2004
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Bioorg Med Chem
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Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.
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Sugawara F
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2004
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Biochemistry
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The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression.
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Sugawara F
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2004
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Biochimica et biophysica acta
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Inhibitory action of emulsified sulfoquinovosyl acylglycerol on mammalian DNA polymerases.
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Sugawara F
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2003
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Lipids
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Analysis of cell cycle regulation by 1-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride (SQMG), an inhibitor of eukaryotic DNA polymerases.
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Sugawara F
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2003
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Biochemical pharmacology
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Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.
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Sugawara F
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2003
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Biochem Pharmacol
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The inhibitory action of pyrrolidine alkaloid, 1,4-dideoxy-1,4-imino-D-ribitol, on eukaryotic DNA polymerases.
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Sugawara F
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2003
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Biochemical and biophysical research communications
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Inhibition of DNA polymerases and DNA topoisomerase II by triterpenes produced by plant callus.
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Sugawara F
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2003
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Biochemical and biophysical research communications
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Molecular action mode of Hippospongic acid A, an inhibitor of gastrulation of starfish embryos.
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Sugawara F
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2003
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Journal of biochemistry
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Effects of glycolipids from spinach on mammalian DNA polymerases.
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Sugawara F
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2003
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Biochemical pharmacology
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A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid.
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Sugawara F
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2003
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Biochimica et biophysica acta
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Flavonoid glycoside: a new inhibitor of eukaryotic DNA polymerase alpha and a new carrier for inhibitor-affinity chromatography.
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Sugawara F
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2003
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Biochem Biophys Res Commun
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A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor.
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Sugawara F
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2003
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Biochem J
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[Structural homology between molecular probes binding site of DNA polymerase beta and DNA topoisomerase II].
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Sugawara F
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2002
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Tanpakushitsu Kakusan Koso
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Actions of derivatives of dehydroaltenusin, a new mammalian DNA polymerase alpha-specific inhibitor.
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Sugawara F
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2002
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Biochem Pharmacol
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A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda.
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Sugawara F
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2002
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The Journal of biological chemistry
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Selective inhibition of the activities of both eukaryotic DNA polymerases and DNA topoisomerases by elenic acid.
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Sugawara F
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2002
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Biochemical pharmacology
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Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases.
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Sugawara F
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2002
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Biochimica et biophysica acta
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Three-dimensional structural model analysis of the binding site of an inhibitor, nervonic acid, of both DNA polymerase beta and HIV-1 reverse transcriptase.
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Sugawara F
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2002
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Journal of biochemistry
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Petasiphenol: a DNA polymerase lambda inhibitor.
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Sugawara F
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2002
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Biochemistry
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Structure-function relationship of synthetic sulfoquinovosyl-acylglycerols as mammalian DNA polymerase inhibitors.
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Sugawara F
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2002
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Arch Biochem Biophys
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Three-dimensional structural model analysis of the binding site of lithocholic acid, an inhibitor of DNA polymerase beta and DNA topoisomerase II.
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Sugawara F
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2001
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J Biochem
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Specific interaction between an oligosaccharide on the tumor cell surface and the novel antitumor agents, sulfoquinovosylacylglycerols.
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Sugawara F
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2001
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Biochemical and biophysical research communications
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Galactosyldiacylglycerol, a mammalian DNA polymerase alpha-specific inhibitor from a sea alga, Petalonia bingbamiae.
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Sugawara F
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2001
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Biol Pharm Bull
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Structure of lithocholic acid binding to the N-terminal 8-kDa domain of DNA polymerase beta.
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Sugawara F
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2000
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Biochemistry
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Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, selectively inhibits the activities of mammalian DNA polymerases and human DNA topoisomerase II.
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Sugawara F
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2000
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Biochemical and biophysical research communications
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Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase.
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Sugawara F
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2000
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Biochem J
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Structure-activity relationship of a novel group of mammalian DNA polymerase inhibitors, synthetic sulfoquinovosylacylglycerols.
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Sugawara F
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2000
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Jpn J Cancer Res
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Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II.
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Sugawara F
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2000
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Journal of molecular biology
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Dehydroaltenusin, a mammalian DNA polymerase alpha inhibitor.
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Sugawara F
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2000
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The Journal of biological chemistry
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Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: inhibitory action on cell proliferation.
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Sugawara F
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2000
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Mutation research
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Differentiation of rat pheochromocytoma cells by fomitellic acids, specific DNA polymerase inhibitors.
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Sugawara F
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2000
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Life Sci
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Action of a new mammalian DNA polymerase inhibitor, sulfoquinovosyldiacylglycerol.
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Sugawara F
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1999
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Biol Pharm Bull
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Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum.
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Sugawara F
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1999
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Bioorganic & medicinal chemistry
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Mode analysis of a fatty acid molecule binding to the N-terminal 8-kDa domain of DNA polymerase beta. A 1:1 complex and binding surface.
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Sugawara F
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1999
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The Journal of biological chemistry
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The cyanogenic glucoside, prunasin (D-mandelonitrile-beta-D-glucoside), is a novel inhibitor of DNA polymerase beta.
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Sugawara F
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1999
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J Biochem
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An ergosterol peroxide, a natural product that selectively enhances the inhibitory effect of linoleic acid on DNA polymerase beta.
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Sugawara F
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1998
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Biol Pharm Bull
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Fomitellic acids, triterpenoid inhibitors of eukaryotic DNA polymerases from a basidiomycete, Fomitella fraxinea.
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Sugawara F
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1998
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Journal of natural products
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Studies on inhibitors of mammalian DNA polymerase alpha and beta: sulfolipids from a pteridophyte, Athyrium niponicum.
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Sugawara F
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1998
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Biochemical pharmacology
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Sulfoquinovosyldiacylglycerol, KM043, a new potent inhibitor of eukaryotic DNA polymerases and HIV-reverse transcriptase type 1 from a marine red alga, Gigartina tenella.
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Sugawara F
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1998
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Chemical & pharmaceutical bulletin
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A mushroom fruiting body-inducing substance inhibits activities of replicative DNA polymerases.
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Sugawara F
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1998
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Biochemical and biophysical research communications
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The inhibitory effect of novel triterpenoid compounds, fomitellic acids, on DNA polymerase beta.
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Sugawara F
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1998
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Biochem J
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4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro.
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Sugawara F
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1998
|
Biochemical pharmacology
|
A 5'-monophosphate form of bredinin selectively inhibits the activities of mammalian DNA polymerases in vitro.
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Sugawara F
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1998
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International journal of molecular medicine
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